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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138243
log Bayes Factor = 13.8285
Chromosome 22   position 50,564,750  (GRCh37) Explore rs138243 on Ensembl!
Variant rs138243 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
H43-H45 Disorders of vitreous body and globe
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.984 0.016 0.000
H30-H36 Disorders of choroid and retina
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.982 0.018 0.000
N17-N19 Renal failure
0.982 0.018 0.000
E10-E14 Diabetes mellitus
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
E10 Insulin-dependent diabetes mellitus
0.976 0.024 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.972 0.028 0.000
D50-D53 Nutritional anaemias
0.971 0.029 0.000
H43 Disorders of vitreous body
0.970 0.030 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.966 0.034 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.963 0.037 0.000
Chapter XX External causes of morbidity and mortality
0.963 0.037 0.000
D50 Iron deficiency anaemia
0.962 0.038 0.000
Chapter XI Diseases of the digestive system
0.956 0.044 0.000
E10.9 Without complications
0.951 0.049 0.000
H02 Other disorders of eyelid
0.948 0.052 0.000
Chapter VI Diseases of the nervous system
0.942 0.058 0.000
K90-K93 Other diseases of the digestive system
0.937 0.063 0.000
H44 Disorders of globe
0.935 0.065 0.000
N18 Chronic renal failure
0.934 0.066 0.000
D50.9 Iron deficiency anaemia, unspecified
0.933 0.067 0.000
H34 Retinal vascular occlusions
0.931 0.069 0.000
T81 Complications of procedures, not elsewhere classified
0.929 0.071 0.000
E20-E35 Disorders of other endocrine glands
0.928 0.072 0.000
Chapter I Certain infectious and parasitic diseases
0.923 0.077 0.000
H43.8 Other disorders of vitreous body
0.914 0.086 0.000
H02.8 Other specified disorders of eyelid
0.913 0.087 0.000
N99-N99 Other disorders of the genitourinary system
0.907 0.093 0.000
M50-M54 Other dorsopathies
0.903 0.097 0.000
N19 Unspecified renal failure
0.902 0.098 0.000
Chapter VIII Diseases of the ear and mastoid process
0.901 0.099 0.000
M15-M19 Arthrosis
0.900 0.100 0.000
H35 Other retinal disorders
0.898 0.102 0.000
Chapter IX Diseases of the circulatory system
0.890 0.110 0.000
E85 Amyloidosis
0.890 0.110 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.889 0.111 0.000
K50-K52 Noninfective enteritis and colitis
0.889 0.111 0.000
K70-K77 Diseases of liver
0.887 0.113 0.000
D80-D89 Certain disorders involving the immune mechanism
0.886 0.114 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.885 0.115 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.882 0.118 0.000
K92 Other diseases of digestive system
0.880 0.120 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.877 0.122 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.875 0.125 0.000
T91 Sequelae of injuries of neck and trunk
0.871 0.129 0.000
M50 Cervical disk disorders
0.864 0.136 0.000
H34.8 Other retinal vascular occlusions
0.864 0.136 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.863 0.137 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.863 0.137 0.000
N17 Acute renal failure
0.863 0.137 0.000
T90 Sequelae of injuries of head
0.862 0.138 0.000
H02.3 Blepharochalasis
0.861 0.139 0.000
G90-G99 Other disorders of the nervous system
0.861 0.139 0.000
E87.7 Fluid overload
0.859 0.141 0.000
S50-S59 Injuries to the elbow and forearm
0.859 0.141 0.000
I60-I69 Cerebrovascular diseases
0.857 0.143 0.000
H80-H83 Diseases of inner ear
0.855 0.145 0.000
T93 Sequelae of injuries of lower limb
0.853 0.147 0.000
N60-N64 Disorders of breast
0.851 0.149 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.848 0.152 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.846 0.154 0.000
I10-I15 Hypertensive diseases
0.846 0.154 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.844 0.156 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.843 0.157 0.000
K65-K67 Diseases of peritoneum
0.843 0.157 0.000
H02.4 Ptosis of eyelid
0.840 0.160 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.839 0.161 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.837 0.163 0.000
K51 Ulcerative colitis
0.835 0.165 0.000
H43.1 Vitreous haemorrhage
0.834 0.166 0.000
H44.2 Degenerative myopia
0.834 0.166 0.000
T86 Failure and rejection of transplanted organs and tissues
0.832 0.168 0.000
E83 Disorders of mineral metabolism
0.830 0.170 0.000
I12 Hypertensive renal disease
0.830 0.170 0.000
M16 Coxarthrosis [arthrosis of hip]
0.829 0.171 0.000
E10.4 With neurological complications
0.829 0.171 0.000
D50.8 Other iron deficiency anaemias
0.826 0.174 0.000
N18.3 Chronic kidney disease, stage 3
0.825 0.175 0.000
G62 Other polyneuropathies
0.824 0.176 0.000
H44.0 Purulent endophthalmitis
0.824 0.176 0.000
E10.1 With ketoacidosis
0.824 0.176 0.000
I63 Cerebral infarction
0.824 0.176 0.000
T79-T79 Certain early complications of trauma
0.823 0.177 0.000
K92.0 Haematemesis
0.822 0.178 0.000
N18.4 Chronic kidney disease, stage 4
0.820 0.180 0.000
Chapter X Diseases of the respiratory system
0.818 0.182 0.000
M50.0 Cervical disk disorder with myelopathy
0.817 0.183 0.000
H02.5 Other disorders affecting eyelid function
0.817 0.183 0.000
E87.0 Hyperosmolality and hypernatraemia
0.815 0.185 0.000
M70-M79 Other soft tissue disorders
0.814 0.186 0.000
D86 Sarcoidosis
0.813 0.187 0.000
N00-N08 Glomerular diseases
0.813 0.187 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.812 0.188 0.000
H35.0 Background retinopathy and retinal vascular changes
0.809 0.191 0.000
K75 Other inflammatory liver diseases
0.808 0.192 0.000
E86 Volume depletion
0.808 0.192 0.000
K92.1 Melaena
0.807 0.193 0.000
H43.3 Other vitreous opacities
0.806 0.194 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.805 0.195 0.000
N18.2 Chronic kidney disease, stage 2
0.805 0.195 0.000
H55-H59 Other disorders of eye and adnexa
0.803 0.197 0.000
S40-S49 Injuries to the shoulder and upper arm
0.801 0.199 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.799 0.201 0.000
E78.0 Pure hypercholesterolaemia
0.798 0.202 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.798 0.202 0.000
E78.1 Pure hyperglyceridaemia
0.797 0.203 0.000
H53-H54 Visual disturbances and blindness
0.797 0.203 0.000
H35.8 Other specified retinal disorders
0.795 0.205 0.000
I12.0 Hypertensive renal disease with renal failure
0.795 0.205 0.000
E78.2 Mixed hyperlipidaemia
0.793 0.207 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.792 0.208 0.000
M65-M68 Disorders of synovium and tendon
0.791 0.209 0.000
T66-T78 Other and unspecified effects of external causes
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.790 0.210 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.790 0.210 0.000
H83 Other diseases of inner ear
0.788 0.212 0.000
X60-X84 Intentional self-harm
0.787 0.213 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.787 0.213 0.000
E10.3 With ophthalmic complications
0.786 0.214 0.000
H34.2 Other retinal artery occlusions
0.786 0.214 0.000
N40-N51 Diseases of male genital organs
0.784 0.216 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.779 0.221 0.000
K91.3 Postoperative intestinal obstruction
0.779 0.221 0.000
M17 Gonarthrosis [arthrosis of knee]
0.779 0.221 0.000
N17.9 Acute renal failure, unspecified
0.777 0.223 0.000
T92 Sequelae of injuries of upper limb
0.776 0.224 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.776 0.224 0.000
E27 Other disorders of adrenal gland
0.774 0.226 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.770 0.230 0.000
E10.5 With peripheral circulatory complications
0.769 0.231 0.000
A80-A89 Viral infections of the central nervous system
0.769 0.231 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.767 0.233 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.767 0.233 0.000
G62.9 Polyneuropathy, unspecified
0.766 0.234 0.000
K52 Other non-infective gastro-enteritis and colitis
0.765 0.235 0.000
E85.4 Organ-limited amyloidosis
0.764 0.236 0.000
T98 Sequelae of other and unspecified effects of external causes
0.763 0.237 0.000
G30-G32 Other degenerative diseases of the nervous system
0.763 0.237 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.763 0.237 0.000
T91.3 Sequelae of injury of spinal cord
0.761 0.239 0.000
H33 Retinal detachments and breaks
0.759 0.241 0.000
K75.8 Other specified inflammatory liver diseases
0.759 0.241 0.000
D52 Folate deficiency anaemia
0.758 0.241 0.000
T87 Complications peculiar to reattachment and amputation
0.758 0.242 0.000
M17.9 Gonarthrosis, unspecified
0.756 0.244 0.000
M50.2 Other cervical disk displacement
0.756 0.244 0.000
J20-J22 Other acute lower respiratory infections
0.756 0.244 0.000
E78.5 Hyperlipidaemia, unspecified
0.754 0.246 0.000
K51.8 Other ulcerative colitis
0.754 0.246 0.000
N18.0 End-stage renal disease
0.753 0.247 0.000
N63 Unspecified lump in breast
0.753 0.247 0.000
H10-H13 Disorders of conjunctiva
0.751 0.249 0.000
E10.2 With renal complications
0.751 0.249 0.000
M80-M85 Disorders of bone density and structure
0.750 0.250 0.000
K73 Chronic hepatitis, not elsewhere classified
0.750 0.250 0.000
I12.9 Hypertensive renal disease without renal failure
0.750 0.250 0.000
E87.6 Hypokalaemia
0.749 0.251 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.749 0.251 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.748 0.252 0.000
M51 Other intervertebral disk disorders
0.748 0.252 0.000
Y83.6 Removal of other organ (partial) (total)
0.747 0.253 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.746 0.254 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.746 0.254 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
B95-B98 Bacterial, viral and other infectious agents
0.742 0.258 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.742 0.258 0.000
E87.3 Alkalosis
0.741 0.259 0.000
N45 Orchitis and epididymitis
0.741 0.259 0.000
K81 Cholecystitis
0.740 0.260 0.000
H83.0 Labyrinthitis
0.740 0.260 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.739 0.261 0.000
G82 Paraplegia and tetraplegia
0.739 0.261 0.000
W20-W49 Exposure to inanimate mechanical forces
0.738 0.261 0.000
H81 Disorders of vestibular function
0.738 0.262 0.000
E24 Cushing's syndrome
0.737 0.263 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
G93 Other disorders of brain
0.736 0.264 0.000
E22 Hyperfunction of pituitary gland
0.734 0.266 0.000
E00-E07 Disorders of thyroid gland
0.734 0.266 0.000
M86-M90 Other osteopathies
0.733 0.267 0.000
E85.9 Amyloidosis, unspecified
0.732 0.268 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.732 0.268 0.000
S20-S29 Injuries to the thorax
0.732 0.268 0.000
Y86 Sequelae of other accidents
0.731 0.269 0.000
T86.0 Bone-marrow transplant rejection
0.729 0.271 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.728 0.271 0.000
H01 Other inflammation of eyelid
0.728 0.272 0.000
K65 Peritonitis
0.728 0.272 0.000
Y57 Other and unspecified drugs and medicaments
0.728 0.272 0.000
S50 Superficial injury of forearm
0.728 0.272 0.000
G83 Other paralytic syndromes
0.727 0.273 0.000
M16.1 Other primary coxarthrosis
0.727 0.273 0.000
Chapter V Mental and behavioural disorders
0.726 0.274 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.725 0.275 0.000
M40-M43 Deforming dorsopathies
0.725 0.275 0.000
M60-M63 Disorders of muscles
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.720 0.279 0.000
T31 Burns classified according to extent of body surface involved
0.720 0.280 0.000
M16.9 Coxarthrosis, unspecified
0.720 0.280 0.000
H36 Retinal disorders in diseases classified elsewhere
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.285 0.000
D86.9 Sarcoidosis, unspecified
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.713 0.286 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.712 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.712 0.288 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.711 0.289 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.711 0.289 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
K80 Cholelithiasis
0.707 0.293 0.000
N25-N29 Other disorders of kidney and ureter
0.707 0.293 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
T95 Sequelae of burns, corrosions and frostbite
0.706 0.294 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.706 0.294 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.706 0.294 0.000
T90.8 Sequelae of other specified injuries of head
0.705 0.295 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.705 0.295 0.000
H31 Other disorders of choroid
0.705 0.295 0.000
H30 Chorioretinal inflammation
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.703 0.297 0.000
K90 Intestinal malabsorption
0.703 0.297 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.702 0.298 0.000
T88.5 Other complications of anaesthesia
0.701 0.299 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.701 0.299 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
E10.8 With unspecified complications
0.700 0.300 0.000
E10.7 With multiple complications
0.700 0.300 0.000
E10.6 With other specified complications
0.700 0.300 0.000
E10.0 With coma
0.700 0.300 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.699 0.301 0.000
E78.8 Other disorders of lipoprotein metabolism
0.697 0.303 0.000
E78.6 Lipoprotein deficiency
0.697 0.303 0.000
E78.4 Other hyperlipidaemia
0.697 0.303 0.000
E78.3 Hyperchylomicronaemia
0.697 0.303 0.000
B25-B34 Other viral diseases
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
D53 Other nutritional anaemias
0.696 0.304 0.000
K51.9 Ulcerative colitis, unspecified
0.696 0.304 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.696 0.304 0.000
H43.9 Disorder of vitreous body, unspecified
0.696 0.304 0.000
H43.2 Crystalline deposits in vitreous body
0.696 0.304 0.000
H43.0 Vitreous prolapse
0.696 0.304 0.000
N60 Benign mammary dysplasia
0.695 0.305 0.000
T93.2 Sequelae of other fractures of lower limb
0.694 0.306 0.000
G95 Other diseases of spinal cord
0.694 0.306 0.000
E29 Testicular dysfunction
0.694 0.306 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.693 0.307 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.693 0.307 0.000
H05 Disorders of orbit
0.693 0.307 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.693 0.307 0.000
M05-M14 Inflammatory polyarthropathies
0.692 0.307 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.692 0.308 0.000
I69 Sequelae of cerebrovascular disease
0.691 0.309 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
E87.4 Mixed disorder of acid-base balance
0.690 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.690 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.309 0.000
Y10-Y34 Event of undetermined intent
0.690 0.309 0.000
Y00-Y09 Assault
0.690 0.309 0.000
X85-X99 Assault
0.690 0.309 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.309 0.000
X50-X57 Overexertion, travel and privation
0.690 0.309 0.000
X30-X39 Exposure to forces of nature
0.690 0.309 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.309 0.000
X10-X19 Contact with heat and hot substances
0.690 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.309 0.000
W75-W84 Other accidental threats to breathing
0.690 0.309 0.000
W65-W74 Accidental drowning and submersion
0.690 0.309 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.309 0.000
V95-V97 Air and space transport accidents
0.690 0.309 0.000
V90-V94 Water transport accidents
0.690 0.309 0.000
V80-V89 Other land transport accidents
0.690 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.309 0.000
D50.1 Sideropenic dysphagia
0.690 0.310 0.000
B35-B49 Mycoses
0.690 0.310 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.689 0.311 0.000
J00-J06 Acute upper respiratory infections
0.689 0.311 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.688 0.312 0.000
I61 Intracerebral haemorrhage
0.688 0.312 0.000
D68 Other coagulation defects
0.687 0.313 0.000
H35.7 Separation of retinal layers
0.686 0.314 0.000
Y40 Systemic antibiotics
0.686 0.314 0.000
E83.5 Disorders of calcium metabolism
0.685 0.315 0.000
M19 Other arthrosis
0.685 0.315 0.000
N41 Inflammatory diseases of prostate
0.684 0.316 0.000
S90-S99 Injuries to the ankle and foot
0.683 0.316 0.000
E65-E68 Obesity and other hyperalimentation
0.683 0.317 0.000
K81.0 Acute cholecystitis
0.681 0.319 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.680 0.320 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.679 0.320 0.000
H02.2 Lagophthalmos
0.679 0.320 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
A00-A09 Intestinal infectious diseases
0.679 0.321 0.000
I63.9 Cerebral infarction, unspecified
0.678 0.322 0.000
M77 Other enthesopathies
0.677 0.323 0.000
J40-J47 Chronic lower respiratory diseases
0.677 0.323 0.000
Y83.3 Surgical operation with formation of external stoma
0.676 0.324 0.000
E28 Ovarian dysfunction
0.676 0.324 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.676 0.324 0.000
E87.2 Acidosis
0.675 0.324 0.000
N61 Inflammatory disorders of breast
0.675 0.325 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.675 0.325 0.000
H00 Hordeolum and chalazion
0.674 0.326 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.673 0.327 0.000
S51 Open wound of forearm
0.673 0.327 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.327 0.000
K66 Other disorders of peritoneum
0.673 0.327 0.000
G62.0 Drug-induced polyneuropathy
0.673 0.327 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.672 0.328 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.672 0.328 0.000
B15-B19 Viral hepatitis
0.672 0.328 0.000
N30-N39 Other diseases of urinary system
0.672 0.328 0.000
H44.9 Disorder of globe, unspecified
0.670 0.330 0.000
H44.8 Other disorders of globe
0.670 0.330 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.670 0.330 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.670 0.330 0.000
H44.5 Degenerated conditions of globe
0.670 0.330 0.000
H44.4 Hypotony of eye
0.670 0.330 0.000
H44.3 Other degenerative disorders of globe
0.670 0.330 0.000
H44.1 Other endophthalmitis
0.670 0.330 0.000
N18.8 Other chronic renal failure
0.670 0.330 0.000
N18.1 Chronic kidney disease, stage 1
0.670 0.330 0.000
J22 Unspecified acute lower respiratory infection
0.669 0.331 0.000
E03 Other hypothyroidism
0.669 0.331 0.000
H34.9 Retinal vascular occlusion, unspecified
0.668 0.332 0.000
H34.1 Central retinal artery occlusion
0.668 0.332 0.000
H34.0 Transient retinal artery occlusion
0.668 0.332 0.000
M50.3 Other cervical disk degeneration
0.667 0.333 0.000
N03 Chronic nephritic syndrome
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.667 0.333 0.000
K72 Hepatic failure, not elsewhere classified
0.667 0.333 0.000
A30-A49 Other bacterial diseases
0.666 0.334 0.000
Y45.1 Salicylates
0.666 0.334 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.666 0.334 0.000
T81.9 Unspecified complication of procedure
0.666 0.334 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.666 0.334 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.666 0.334 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.666 0.334 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.665 0.334 0.000
E34 Other endocrine disorders
0.665 0.334 0.000
E32 Diseases of thymus
0.665 0.334 0.000
E31 Polyglandular dysfunction
0.665 0.334 0.000
E30 Disorders of puberty, not elsewhere classified
0.665 0.334 0.000
E26 Hyperaldosteronism
0.665 0.334 0.000
E25 Adrenogenital disorders
0.665 0.334 0.000
E20 Hypoparathyroidism
0.665 0.334 0.000
E13 Other specified diabetes mellitus
0.664 0.336 0.000
E23 Hypofunction and other disorders of pituitary gland
0.663 0.337 0.000
H35.6 Retinal haemorrhage
0.663 0.337 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.663 0.337 0.000
T88.4 Failed or difficult intubation
0.663 0.337 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.663 0.337 0.000
H57 Other disorders of eye and adnexa
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.662 0.338 0.000
B65-B83 Helminthiases
0.662 0.338 0.000
B50-B64 Protozoal diseases
0.662 0.338 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.662 0.338 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.662 0.338 0.000
A75-A79 Rickettsioses
0.662 0.338 0.000
A70-A74 Other diseases caused by chlamydiae
0.662 0.338 0.000
A65-A69 Other spirochaetal diseases
0.662 0.338 0.000
A20-A28 Certain zoonotic bacterial diseases
0.662 0.338 0.000
A15-A19 Tuberculosis
0.662 0.338 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.662 0.338 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.660 0.340 0.000
S60-S69 Injuries to the wrist and hand
0.660 0.340 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.660 0.340 0.000
G70-G73 Diseases of myoneural junction and muscle
0.659 0.340 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.659 0.341 0.000
T90.9 Sequelae of unspecified injury of head
0.659 0.341 0.000
A87 Viral meningitis
0.658 0.342 0.000
K92.9 Disease of digestive system, unspecified
0.658 0.342 0.000
H35.9 Retinal disorder, unspecified
0.657 0.343 0.000
H65-H75 Diseases of middle ear and mastoid
0.657 0.343 0.000
Q80-Q89 Other congenital malformations
0.657 0.343 0.000
R47-R49 Symptoms and signs involving speech and voice
0.655 0.345 0.000
T90.5 Sequelae of intracranial injury
0.654 0.346 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.654 0.346 0.000
I63.8 Other cerebral infarction
0.652 0.347 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.652 0.348 0.000
D86.1 Sarcoidosis of lymph nodes
0.652 0.348 0.000
D51 Vitamin B12 deficiency anaemia
0.651 0.349 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.651 0.349 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.650 0.349 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
K65.0 Acute peritonitis
0.649 0.351 0.000
H60-H62 Diseases of external ear
0.649 0.351 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.648 0.352 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.648 0.352 0.000
Y83.5 Amputation of limb(s)
0.647 0.353 0.000
N99.0 Postprocedural renal failure
0.646 0.354 0.000
M15 Polyarthrosis
0.646 0.354 0.000
J20 Acute bronchitis
0.645 0.355 0.000
G83.4 Cauda equina syndrome
0.645 0.355 0.000
Y85 Sequelae of transport accidents
0.644 0.356 0.000
H35.5 Hereditary retinal dystrophy
0.644 0.356 0.000
H35.2 Other proliferative retinopathy
0.644 0.356 0.000
H35.1 Retinopathy of prematurity
0.644 0.356 0.000
G63.2 Diabetic polyneuropathy
0.643 0.357 0.000
H52 Disorders of refraction and accommodation
0.642 0.357 0.000
K74 Fibrosis and cirrhosis of liver
0.642 0.358 0.000
G93.3 Postviral fatigue syndrome
0.642 0.358 0.000
T78 Adverse effects, not elsewhere classified
0.642 0.358 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.360 0.000
G30 Alzheimer's disease
0.640 0.360 0.000
G96 Other disorders of central nervous system
0.639 0.361 0.000
K91.4 Colostomy and enterostomy malfunction
0.639 0.361 0.000
S42 Fracture of shoulder and upper arm
0.639 0.361 0.000
H81.0 Meniere's disease
0.639 0.361 0.000
I00-I02 Acute rheumatic fever
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.638 0.362 0.000
E85.8 Other amyloidosis
0.638 0.362 0.000
E85.3 Secondary systemic amyloidosis
0.638 0.362 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.638 0.362 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.638 0.362 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.638 0.362 0.000
G60 Hereditary and idiopathic neuropathy
0.638 0.362 0.000
G64 Other disorders of peripheral nervous system
0.638 0.362 0.000
I05-I09 Chronic rheumatic heart diseases
0.637 0.363 0.000
D86.0 Sarcoidosis of lung
0.637 0.363 0.000
Q60-Q64 Congenital malformations of the urinary system
0.636 0.363 0.000
T31.0 Burns involving less than 10% of body surface
0.636 0.364 0.000
K77 Liver disorders in diseases classified elsewhere
0.636 0.364 0.000
K71 Toxic liver disease
0.636 0.364 0.000
S40 Superficial injury of shoulder and upper arm
0.635 0.364 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.635 0.365 0.000
D84 Other immunodeficiencies
0.635 0.365 0.000
D83 Common variable immunodeficiency
0.635 0.365 0.000
D82 Immunodeficiency associated with other major defects
0.635 0.365 0.000
D81 Combined immunodeficiencies
0.635 0.365 0.000
D80 Immunodeficiency with predominantly antibody defects
0.635 0.365 0.000
M51.2 Other specified intervertebral disk displacement
0.635 0.365 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.635 0.365 0.000
T88.9 Complication of surgical and medical care, unspecified
0.635 0.365 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.635 0.365 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.635 0.365 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.635 0.365 0.000
T88.2 Shock due to anaesthesia
0.635 0.365 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.635 0.365 0.000
T88.0 Infection following immunisation
0.635 0.365 0.000
K85 Acute pancreatitis
0.633 0.367 0.000
T90.4 Sequelae of injury of eye and orbit
0.632 0.367 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.632 0.368 0.000
N04 Nephrotic syndrome
0.632 0.368 0.000
J02 Acute pharyngitis
0.631 0.369 0.000
G61 Inflammatory polyneuropathy
0.631 0.369 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.631 0.369 0.000
E83.4 Disorders of magnesium metabolism
0.631 0.369 0.000
K92.8 Other specified diseases of digestive system
0.631 0.369 0.000
H54 Blindness and low vision
0.631 0.369 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.631 0.369 0.000
N48 Other disorders of penis
0.631 0.369 0.000
M53 Other dorsopathies, not elsewhere classified
0.630 0.370 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.629 0.371 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.629 0.371 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.629 0.371 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.629 0.371 0.000
T83.2 Mechanical complication of graft of urinary organ
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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