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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138325697
log Bayes Factor = 2.99756
Chromosome 1   position 194,689,514  (GRCh37) Explore rs138325697 on Ensembl!
Variant rs138325697 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
# Top node
0.998 0.002 0.000
K70-K77 Diseases of liver
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.986 0.014 0.000
K70 Alcoholic liver disease
0.985 0.015 0.000
S00-S09 Injuries to the head
0.981 0.019 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.974 0.026 0.000
S01 Open wound of head
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.968 0.032 0.000
K80 Cholelithiasis
0.968 0.032 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.963 0.037 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.945 0.055 0.000
K81 Cholecystitis
0.943 0.057 0.000
K70.9 Alcoholic liver disease, unspecified
0.934 0.066 0.000
K76 Other diseases of liver
0.927 0.073 0.000
K02 Dental caries
0.927 0.073 0.000
M54 Dorsalgia
0.923 0.077 0.000
M06 Other rheumatoid arthritis
0.918 0.082 0.000
M45-M49 Spondylopathies
0.910 0.090 0.000
K70.3 Alcoholic cirrhosis of liver
0.905 0.095 0.000
Chapter VII Diseases of the eye and adnexa
0.903 0.097 0.000
M06.9 Rheumatoid arthritis, unspecified
0.895 0.105 0.000
S01.8 Open wound of other parts of head
0.893 0.107 0.000
K02.9 Dental caries, unspecified
0.893 0.107 0.000
S00 Superficial injury of head
0.884 0.116 0.000
K74 Fibrosis and cirrhosis of liver
0.879 0.121 0.000
O60-O75 Complications of labour and delivery
0.879 0.121 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.878 0.122 0.000
M20-M25 Other joint disorders
0.878 0.122 0.000
K05 Gingivitis and periodontal diseases
0.875 0.125 0.000
K35-K38 Diseases of appendix
0.873 0.127 0.000
Chapter VIII Diseases of the ear and mastoid process
0.871 0.129 0.000
K81.1 Chronic cholecystitis
0.864 0.136 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.863 0.137 0.000
Chapter VI Diseases of the nervous system
0.863 0.137 0.000
M50 Cervical disk disorders
0.853 0.147 0.000
M54.3 Sciatica
0.850 0.150 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.850 0.150 0.000
K76.6 Portal hypertension
0.836 0.164 0.000
M25 Other joint disorders, not elsewhere classified
0.832 0.168 0.000
S01.1 Open wound of eyelid and periocular area
0.825 0.175 0.000
S01.2 Open wound of nose
0.824 0.176 0.000
M47 Spondylosis
0.802 0.198 0.000
M25.7 Osteophyte
0.801 0.199 0.000
S01.9 Open wound of head, part unspecified
0.797 0.203 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.793 0.207 0.000
G90-G99 Other disorders of the nervous system
0.792 0.208 0.000
K14 Diseases of tongue
0.791 0.209 0.000
K70.0 Alcoholic fatty liver
0.790 0.209 0.000
K81.0 Acute cholecystitis
0.790 0.210 0.000
S06 Intracranial injury
0.785 0.215 0.000
M54.1 Radiculopathy
0.784 0.215 0.000
S00.1 Contusion of eyelid and periocular area
0.784 0.216 0.000
K04 Diseases of pulp and periapical tissues
0.783 0.217 0.000
M65-M68 Disorders of synovium and tendon
0.782 0.218 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.782 0.218 0.000
M86-M90 Other osteopathies
0.781 0.219 0.000
S01.5 Open wound of lip and oral cavity
0.779 0.221 0.000
K05.3 Chronic periodontitis
0.778 0.222 0.000
K74.6 Other and unspecified cirrhosis of liver
0.778 0.222 0.000
S70-S79 Injuries to the hip and thigh
0.774 0.226 0.000
H10-H13 Disorders of conjunctiva
0.771 0.229 0.000
K72 Hepatic failure, not elsewhere classified
0.770 0.230 0.000
Chapter II Neoplasms
0.770 0.230 0.000
M54.36 Sciatica (Lumbar region)
0.767 0.233 0.000
H04 Disorders of lachrymal system
0.767 0.233 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.766 0.234 0.000
K83 Other diseases of biliary tract
0.760 0.239 0.000
M15-M19 Arthrosis
0.760 0.240 0.000
M54.9 Dorsalgia, unspecified
0.760 0.240 0.000
M25.77 Osteophyte (Ankle and foot)
0.757 0.243 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.756 0.244 0.000
M48 Other spondylopathies
0.755 0.245 0.000
K70.1 Alcoholic hepatitis
0.755 0.245 0.000
K76.9 Liver disease, unspecified
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.750 0.250 0.000
H00 Hordeolum and chalazion
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
K01 Embedded and impacted teeth
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.746 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.745 0.255 0.000
M53 Other dorsopathies, not elsewhere classified
0.743 0.257 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.743 0.257 0.000
K81.9 Cholecystitis, unspecified
0.742 0.258 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.741 0.259 0.000
M91-M94 Chondropathies
0.741 0.259 0.000
O66 Other obstructed labour
0.739 0.261 0.000
K37 Unspecified appendicitis
0.738 0.262 0.000
S01.3 Open wound of ear
0.733 0.267 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.733 0.267 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.730 0.270 0.000
S01.0 Open wound of scalp
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
K86 Other diseases of pancreas
0.727 0.273 0.000
M35 Other systemic involvement of connective tissue
0.726 0.274 0.000
M50.2 Other cervical disk displacement
0.726 0.274 0.000
G30-G32 Other degenerative diseases of the nervous system
0.725 0.275 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
H80-H83 Diseases of inner ear
0.717 0.283 0.000
Chapter XX External causes of morbidity and mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.285 0.000
K75 Other inflammatory liver diseases
0.715 0.285 0.000
K73 Chronic hepatitis, not elsewhere classified
0.715 0.285 0.000
K71 Toxic liver disease
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
H90-H95 Other disorders of ear
0.713 0.287 0.000
O48 Prolonged pregnancy
0.711 0.288 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.710 0.290 0.000
K35 Acute appendicitis
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.293 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.707 0.293 0.000
K70.4 Alcoholic hepatic failure
0.706 0.293 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.706 0.293 0.000
C51-C58 Malignant neoplasms of female genital organs
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S05 Injury of eye and orbit
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
S60-S69 Injuries to the wrist and hand
0.704 0.296 0.000
M06.0 Seronegative rheumatoid arthritis
0.701 0.299 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.700 0.300 0.000
S50-S59 Injuries to the elbow and forearm
0.700 0.300 0.000
M54.6 Pain in thoracic spine
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
K10 Other diseases of jaws
0.698 0.301 0.000
K09 Cysts of oral region, not elsewhere classified
0.698 0.301 0.000
K03 Other diseases of hard tissues of teeth
0.698 0.301 0.000
K00 Disorders of tooth development and eruption
0.698 0.301 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.698 0.301 0.000
H25-H28 Disorders of lens
0.698 0.302 0.000
T79-T79 Certain early complications of trauma
0.696 0.303 0.000
S01.7 Multiple open wounds of head
0.696 0.304 0.000
S01.4 Open wound of cheek and temporomandibular area
0.696 0.304 0.000
K80.4 Calculus of bile duct with cholecystitis
0.696 0.304 0.000
K90-K93 Other diseases of the digestive system
0.696 0.304 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.696 0.304 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.694 0.306 0.000
M50.0 Cervical disk disorder with myelopathy
0.694 0.306 0.000
K80.3 Calculus of bile duct with cholangitis
0.694 0.306 0.000
K80.8 Other cholelithiasis
0.694 0.306 0.000
M05 Seropositive rheumatoid arthritis
0.693 0.307 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.307 0.000
S02 Fracture of skull and facial bones
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.308 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
K05.6 Periodontal disease, unspecified
0.691 0.309 0.000
T66-T78 Other and unspecified effects of external causes
0.691 0.309 0.000
M46 Other inflammatory spondylopathies
0.690 0.310 0.000
K74.0 Hepatic fibrosis
0.690 0.310 0.000
M25.76 Osteophyte (Lower leg)
0.687 0.313 0.000
O42 Premature rupture of membranes
0.687 0.313 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.686 0.313 0.000
M54.16 Radiculopathy (Lumbar region)
0.685 0.315 0.000
O36 Maternal care for other known or suspected foetal problems
0.684 0.316 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.682 0.318 0.000
K65-K67 Diseases of peritoneum
0.681 0.318 0.000
S90-S99 Injuries to the ankle and foot
0.679 0.320 0.000
M54.37 Sciatica (Lumbosacral region)
0.679 0.321 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.321 0.000
M12 Other specific arthropathies
0.678 0.321 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.321 0.000
M08 Juvenile arthritis
0.678 0.321 0.000
S00.0 Superficial injury of scalp
0.678 0.322 0.000
S00.8 Superficial injury of other parts of head
0.678 0.322 0.000
O85-O92 Complications predominantly related to the puerperium
0.678 0.322 0.000
H00.1 Chalazion
0.678 0.322 0.000
M17 Gonarthrosis [arthrosis of knee]
0.677 0.323 0.000
O61 Failed induction of labour
0.677 0.323 0.000
K81.8 Other cholecystitis
0.676 0.324 0.000
M13 Other arthritis
0.673 0.327 0.000
K12 Stomatitis and related lesions
0.671 0.329 0.000
K07 Dentofacial anomalies [including malocclusion]
0.671 0.329 0.000
M47.2 Other spondylosis with radiculopathy
0.669 0.331 0.000
M25.4 Effusion of joint
0.669 0.331 0.000
D00-D09 In situ neoplasms
0.668 0.332 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.666 0.333 0.000
K76.7 Hepatorenal syndrome
0.665 0.335 0.000
K76.5 Hepatic veno-occlusive disease
0.665 0.335 0.000
K76.4 Peliosis hepatis
0.665 0.335 0.000
K76.3 Infarction of liver
0.665 0.335 0.000
K76.2 Central haemorrhagic necrosis of liver
0.665 0.335 0.000
K76.1 Chronic passive congestion of liver
0.665 0.335 0.000
K02.8 Other dental caries
0.664 0.335 0.000
K02.5 Caries with pulp exposure
0.664 0.335 0.000
K02.4 Odontoclasia
0.664 0.335 0.000
K02.3 Arrested dental caries
0.664 0.335 0.000
K02.2 Caries of cementum
0.664 0.335 0.000
K02.1 Caries of dentin
0.664 0.335 0.000
K02.0 Caries limited to enamel
0.664 0.335 0.000
K11 Diseases of salivary glands
0.662 0.338 0.000
O41 Other disorders of amniotic fluid and membranes
0.662 0.338 0.000
M54.8 Other dorsalgia
0.662 0.338 0.000
M54.4 Lumbago with sciatica
0.662 0.338 0.000
M54.0 Panniculitis affecting regions of neck and back
0.662 0.338 0.000
O62 Abnormalities of forces of labour
0.661 0.339 0.000
M21 Other acquired deformities of limbs
0.661 0.339 0.000
M11 Other crystal arthropathies
0.660 0.340 0.000
M24 Other specific joint derangements
0.659 0.341 0.000
H04.1 Other disorders of lachrymal gland
0.659 0.341 0.000
M06.8 Other specified rheumatoid arthritis
0.658 0.341 0.000
M06.4 Inflammatory polyarthropathy
0.658 0.341 0.000
M06.3 Rheumatoid nodule
0.658 0.341 0.000
M06.2 Rheumatoid bursitis
0.658 0.341 0.000
M06.1 Adult-onset Still's disease
0.658 0.341 0.000
H55-H59 Other disorders of eye and adnexa
0.656 0.344 0.000
O30 Multiple gestation
0.655 0.345 0.000
K83.0 Cholangitis
0.655 0.345 0.000
K85 Acute pancreatitis
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.652 0.348 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.651 0.349 0.000
C64-C68 Malignant neoplasms of urinary tract
0.651 0.349 0.000
G93 Other disorders of brain
0.650 0.350 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.650 0.350 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.649 0.351 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.648 0.352 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.648 0.352 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.646 0.354 0.000
D60-D64 Aplastic and other anaemias
0.645 0.354 0.000
M10 Gout
0.645 0.355 0.000
M07 Psoriatic and enteropathic arthropathies
0.645 0.355 0.000
M48.0 Spinal stenosis
0.644 0.356 0.000
K08 Other disorders of teeth and supporting structures
0.644 0.356 0.000
C54 Malignant neoplasm of corpus uteri
0.643 0.357 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.642 0.358 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.641 0.358 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.641 0.358 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.641 0.358 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.641 0.358 0.000
O75.8 Other specified complications of labour and delivery
0.641 0.359 0.000
O70 Perineal laceration during delivery
0.640 0.360 0.000
M65 Synovitis and tenosynovitis
0.640 0.360 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.640 0.360 0.000
K14.9 Disease of tongue, unspecified
0.639 0.361 0.000
H65-H75 Diseases of middle ear and mastoid
0.639 0.361 0.000
M54.39 Sciatica (Site unspecified)
0.639 0.361 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.638 0.362 0.000
M31 Other necrotising vasculopathies
0.638 0.362 0.000
M54.2 Cervicalgia
0.636 0.364 0.000
M40-M43 Deforming dorsopathies
0.635 0.364 0.000
S00.7 Multiple superficial injuries of head
0.634 0.366 0.000
S00.5 Superficial injury of lip and oral cavity
0.634 0.366 0.000
S00.4 Superficial injury of ear
0.634 0.366 0.000
S00.3 Superficial injury of nose
0.634 0.366 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.634 0.366 0.000
K04.6 Periapical abscess with sinus
0.634 0.366 0.000
O47 False labour
0.634 0.366 0.000
O63 Long labour
0.633 0.367 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.632 0.368 0.000
H10 Conjunctivitis
0.631 0.369 0.000
K74.5 Biliary cirrhosis, unspecified
0.630 0.370 0.000
K74.4 Secondary biliary cirrhosis
0.630 0.370 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.630 0.370 0.000
K74.1 Hepatic sclerosis
0.630 0.370 0.000
O74 Complications of anaesthesia during labour and delivery
0.630 0.370 0.000
O73 Retained placenta and membranes, without haemorrhage
0.630 0.370 0.000
O71 Other obstetric trauma
0.630 0.370 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.630 0.370 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.630 0.370 0.000
O60 Preterm delivery
0.630 0.370 0.000
O45 Premature separation of placenta [abruptio placentae]
0.630 0.370 0.000
O44 Placenta praevia
0.630 0.370 0.000
O43 Placental disorders
0.630 0.370 0.000
O33 Maternal care for known or suspected disproportion
0.630 0.370 0.000
O31 Complications specific to multiple gestation
0.630 0.370 0.000
O40 Polyhydramnios
0.630 0.370 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.630 0.370 0.000
S00.9 Superficial injury of head, part unspecified
0.629 0.370 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.629 0.370 0.000
M34 Systemic sclerosis
0.629 0.370 0.000
M33 Dermatopolymyositis
0.629 0.370 0.000
M32 Systemic lupus erythematosus
0.629 0.370 0.000
M30 Polyarteritis nodosa and related conditions
0.629 0.370 0.000
H60-H62 Diseases of external ear
0.629 0.371 0.000
H01 Other inflammation of eyelid
0.628 0.371 0.000
H43-H45 Disorders of vitreous body and globe
0.628 0.372 0.000
M47.8 Other spondylosis
0.627 0.372 0.000
K05.2 Acute periodontitis
0.627 0.373 0.000
K05.5 Other periodontal diseases
0.627 0.373 0.000
K05.4 Periodontosis
0.627 0.373 0.000
K05.1 Chronic gingivitis
0.627 0.373 0.000
K05.0 Acute gingivitis
0.627 0.373 0.000
M89 Other disorders of bone
0.627 0.373 0.000
H53-H54 Visual disturbances and blindness
0.626 0.374 0.000
K38 Other diseases of appendix
0.626 0.374 0.000
K36 Other appendicitis
0.626 0.374 0.000
M35.0 Sicca syndrome [Sjogren]
0.624 0.376 0.000
H11 Other disorders of conjunctiva
0.623 0.377 0.000
K35.8 Acute appendicitis, other and unspecified
0.623 0.377 0.000
S72 Fracture of femur
0.622 0.378 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.379 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.620 0.380 0.000
M50.1 Cervical disk disorder with radiculopathy
0.620 0.380 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.620 0.380 0.000
H04.2 Epiphora
0.619 0.381 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.619 0.381 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.619 0.381 0.000
M45 Ankylosing spondylitis
0.618 0.382 0.000
O72 Postpartum haemorrhage
0.617 0.383 0.000
M47.1 Other spondylosis with myelopathy
0.616 0.384 0.000
G30 Alzheimer's disease
0.616 0.384 0.000
G96 Other disorders of central nervous system
0.615 0.384 0.000
K14.0 Glossitis
0.614 0.386 0.000
H25 Senile cataract
0.613 0.387 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.612 0.388 0.000
M50.9 Cervical disk disorder, unspecified
0.612 0.388 0.000
M50.8 Other cervical disk disorders
0.612 0.388 0.000
G95 Other diseases of spinal cord
0.610 0.389 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.610 0.390 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.609 0.390 0.000
M54.35 Sciatica (Thoracolumbar region)
0.609 0.390 0.000
M54.34 Sciatica-Thoracic
0.609 0.390 0.000
M54.33 Sciatica-Cervicothoracic
0.609 0.390 0.000
M54.32 Sciatica-Cervical
0.609 0.390 0.000
M54.31 Sciatica-Occipit-atl-axl
0.609 0.390 0.000
M54.30 Sciatica (Multiple sites in spine)
0.609 0.390 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.609 0.391 0.000
H05 Disorders of orbit
0.609 0.391 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.609 0.391 0.000
D10-D36 Benign neoplasms
0.609 0.391 0.000
M50.3 Other cervical disk degeneration
0.608 0.392 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.607 0.392 0.000
K72.9 Hepatic failure, unspecified
0.607 0.393 0.000
S09 Other and unspecified injuries of head
0.604 0.396 0.000
K74.3 Primary biliary cirrhosis
0.603 0.397 0.000
S06.5 Traumatic subdural haemorrhage
0.601 0.399 0.000
M51 Other intervertebral disk disorders
0.601 0.399 0.000
C54.1 Endometrium
0.599 0.401 0.000
M22 Disorders of patella
0.599 0.401 0.000
M23 Internal derangement of knee
0.597 0.403 0.000
M25.9 Joint disorder, unspecified
0.596 0.403 0.000
M25.8 Other specified joint disorders
0.596 0.403 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.596 0.403 0.000
M25.3 Other instability of joint
0.596 0.403 0.000
M25.2 Flail joint
0.596 0.403 0.000
M25.1 Fistula of joint
0.596 0.403 0.000
M25.0 Haemarthrosis
0.596 0.403 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.596 0.404 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.596 0.404 0.000
H92 Otalgia and effusion of ear
0.596 0.404 0.000
L40-L45 Papulosquamous disorders
0.595 0.405 0.000
M47.9 Spondylosis, unspecified
0.594 0.406 0.000
H83 Other diseases of inner ear
0.594 0.406 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.593 0.407 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.592 0.408 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.592 0.408 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.591 0.409 0.000
S06.2 Diffuse brain injury
0.591 0.409 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.591 0.409 0.000
O00-O08 Pregnancy with abortive outcome
0.590 0.410 0.000
K86.3 Pseudocyst of pancreas
0.588 0.412 0.000
K01.1 Impacted teeth
0.583 0.417 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.582 0.417 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.580 0.420 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.579 0.421 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.579 0.421 0.000
W00-W19 Falls
0.578 0.422 0.000
M17.1 Other primary gonarthrosis
0.578 0.422 0.000
D55-D59 Haemolytic anaemias
0.578 0.422 0.000
S12 Fracture of neck
0.577 0.423 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.577 0.423 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.575 0.425 0.000
M25.79 Osteophyte (Site unspecified)
0.575 0.425 0.000
M25.74 Osteophyte (Hand)
0.575 0.425 0.000
M25.73 Osteophyte (Forearm)
0.575 0.425 0.000
M25.72 Osteophyte (Upper arm)
0.575 0.425 0.000
M25.71 Osteophyte (Shoulder region)
0.575 0.425 0.000
M25.70 Osteophyte (Multiple sites)
0.575 0.425 0.000
K04.8 Radicular cyst
0.574 0.426 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.574 0.426 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.573 0.427 0.000
K04.7 Periapical abscess without sinus
0.573 0.427 0.000
G12 Spinal muscular atrophy and related syndromes
0.571 0.429 0.000
O80-O84 Delivery
0.571 0.429 0.000
H80 Otosclerosis
0.570 0.430 0.000
O36.8 Maternal care for other specified foetal problems
0.570 0.430 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.569 0.431 0.000
M17.5 Other secondary gonarthrosis
0.569 0.431 0.000
G72 Other myopathies
0.569 0.431 0.000
L60-L75 Disorders of skin appendages
0.568 0.432 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.568 0.432 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.568 0.432 0.000
G91 Hydrocephalus
0.568 0.432 0.000
G90 Disorders of autonomic nervous system
0.568 0.432 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.568 0.432 0.000
G92 Toxic encephalopathy
0.568 0.432 0.000
K14.6 Glossodynia
0.567 0.432 0.000
K14.5 Plicated tongue
0.567 0.432 0.000
K14.4 Atrophy of tongue papillae
0.567 0.432 0.000
K14.3 Hypertrophy of tongue papillae
0.567 0.432 0.000
K14.2 Median rhomboid glossitis
0.567 0.432 0.000
K14.1 Geographic tongue
0.567 0.432 0.000
T17 Foreign body in respiratory tract
0.566 0.433 0.000
T92 Sequelae of injuries of upper limb
0.565 0.434 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.564 0.436 0.000
M25.78 Osteophyte (Other)
0.564 0.436 0.000
S32 Fracture of lumbar spine and pelvis
0.563 0.437 0.000
S06.9 Intracranial injury, unspecified
0.563 0.437 0.000
S06.8 Other intracranial injuries
0.563 0.437 0.000
S06.7 Intracranial injury with prolonged coma
0.563 0.437 0.000
S06.4 Epidural haemorrhage
0.563 0.437 0.000
S06.3 Focal brain injury
0.563 0.437 0.000
S06.1 Traumatic cerebral oedema
0.563 0.437 0.000
S06.0 Concussion
0.563 0.437 0.000
H90 Conductive and sensorineural hearing loss
0.563 0.437 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.563 0.437 0.000
M54.19 Radiculopathy (Site unspecified)
0.562 0.437 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.562 0.437 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.562 0.437 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.562 0.437 0.000
M54.14 Radiculopathy (Thoracic region)
0.562 0.437 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.562 0.437 0.000
M54.12 Radiculopathy (Cervical region)
0.562 0.437 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.562 0.437 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.562 0.437 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.561 0.438 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.561 0.438 0.000
K04.3 Abnormal hard tissue formation in pulp
0.561 0.438 0.000
K04.2 Pulp degeneration
0.561 0.438 0.000
K04.1 Necrosis of pulp
0.561 0.438 0.000
K04.0 Pulpitis
0.561 0.438 0.000
H02 Other disorders of eyelid
0.561 0.439 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.561 0.439 0.000
M66 Spontaneous rupture of synovium and tendon
0.561 0.439 0.000
M90 Osteopathies in diseases classified elsewhere
0.560 0.440 0.000
M88 Paget's disease of bone [osteitis deformans]
0.560 0.440 0.000
M86 Osteomyelitis
0.560 0.440 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.559 0.441 0.000
M87 Osteonecrosis
0.558 0.441 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.558 0.442 0.000
M94 Other disorders of cartilage
0.557 0.443 0.000
G20-G26 Extrapyramidal and movement disorders
0.557 0.443 0.000
S80-S89 Injuries to the knee and lower leg
0.556 0.443 0.000
C56 Malignant neoplasm of ovary
0.556 0.444 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.556 0.444 0.000
K04.5 Chronic apical periodontitis
0.555 0.445 0.000
S79 Other and unspecified injuries of hip and thigh
0.555 0.445 0.000
S78 Traumatic amputation of hip and thigh
0.555 0.445 0.000
S77 Crushing injury of hip and thigh
0.555 0.445 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.555 0.445 0.000
S75 Injury of blood vessels at hip and thigh level
0.555 0.445 0.000
S74 Injury of nerves at hip and thigh level
0.555 0.445 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.555 0.445 0.000
S71 Open wound of hip and thigh
0.555 0.445 0.000
S70 Superficial injury of hip and thigh
0.555 0.445 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.555 0.445 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.554 0.446 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.553 0.447 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.552 0.448 0.000
K72.1 Chronic hepatic failure
0.552 0.448 0.000
K72.0 Acute and subacute hepatic failure
0.552 0.448 0.000
M19 Other arthrosis
0.552 0.448 0.000
H40-H42 Glaucoma
0.552 0.448 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.552 0.448 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.552 0.448 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.552 0.448 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.552 0.448 0.000
M25.47 Effusion of joint (Ankle and foot)
0.551 0.448 0.000
M84 Disorders of continuity of bone
0.551 0.449 0.000
S69 Other and unspecified injuries of wrist and hand
0.550 0.450 0.000
H04.9 Disorder of lachrymal system, unspecified
0.550 0.450 0.000
H04.8 Other disorders of lachrymal system
0.550 0.450 0.000
H04.6 Other changes in lachrymal passages
0.550 0.450 0.000
H04.4 Chronic inflammation of lachrymal passages
0.550 0.450 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.550 0.450 0.000
H04.0 Dacryoadenitis
0.550 0.450 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.549 0.450 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.549 0.451 0.000
Q80-Q89 Other congenital malformations
0.549 0.451 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.549 0.451 0.000
Q50-Q56 Congenital malformations of genital organs
0.549 0.451 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.549 0.451 0.000
Q35-Q37 Cleft lip and cleft palate
0.549 0.451 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.549 0.451 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.549 0.451 0.000
Q00-Q07 Congenital malformations of the nervous system
0.549 0.451 0.000
O32.1 Maternal care for breech presentation
0.549 0.451 0.000
O70.1 Second degree perineal laceration during delivery
0.549 0.451 0.000
K14.8 Other diseases of tongue
0.548 0.452 0.000
M54.5 Low back pain
0.548 0.452 0.000
S62 Fracture at wrist and hand level
0.547 0.453 0.000
H18 Other disorders of cornea
0.547 0.453 0.000
K83.9 Disease of biliary tract, unspecified
0.545 0.455 0.000
K83.5 Biliary cyst
0.545 0.455 0.000
K83.4 Spasm of sphincter of Oddi
0.545 0.455 0.000
K83.3 Fistula of bile duct
0.545 0.455 0.000
K83.2 Perforation of bile duct
0.545 0.455 0.000
M15 Polyarthrosis
0.545 0.455 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.545 0.455 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.545 0.455 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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