TreeWAS – Variant ID: rs1383808

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
# Top node	0.197	0.803
Chapter XXI Factors influencing health status and contact with health services	0.205	0.795
Chapter IX Diseases of the circulatory system	0.215	0.785
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.235	0.765
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.253	0.747
I10-I15 Hypertensive diseases	0.261	0.739
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.267	0.733
I10 Essential (primary) hypertension	0.302	0.698
I60-I69 Cerebrovascular diseases	0.302	0.698
Chapter X Diseases of the respiratory system	0.304	0.696
Z86 Personal history of certain other diseases	0.316	0.684
Chapter V Mental and behavioural disorders	0.321	0.679
I70-I79 Diseases of arteries, arterioles and capillaries	0.324	0.676
Z70-Z76 Persons encountering health services in other circumstances	0.329	0.671
Z40-Z54 Persons encountering health services for specific procedures and health care	0.329	0.671
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.337	0.662
Chapter I Certain infectious and parasitic diseases	0.343	0.657
M05-M14 Inflammatory polyarthropathies	0.344	0.656
Z92 Personal history of medical treatment	0.352	0.648
Z00-Z13 Persons encountering health services for examination and investigation	0.357	0.643
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.365	0.635
Chapter IV Endocrine, nutritional and metabolic diseases	0.369	0.631
Chapter VIII Diseases of the ear and mastoid process	0.371	0.629
Chapter VII Diseases of the eye and adnexa	0.372	0.628
Z86.7 Personal history of diseases of the circulatory system	0.374	0.626
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.383	0.617
S00-S09 Injuries to the head	0.386	0.614
Z95 Presence of cardiac and vascular implants and grafts	0.389	0.610
M20-M25 Other joint disorders	0.391	0.609
Z72 Problems related to lifestyle	0.404	0.596
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.405	0.595
M70-M79 Other soft tissue disorders	0.412	0.588
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.415	0.585
Z83 Family history of other specific disorders	0.415	0.585
Chapter XX External causes of morbidity and mortality	0.415	0.585
I30-I52 Other forms of heart disease	0.415	0.585
Z90 Acquired absence of organs, not elsewhere classified	0.416	0.584
Z50 Care involving use of rehabilitation procedures	0.416	0.584
T81 Complications of procedures, not elsewhere classified	0.417	0.583
Chapter XVI Certain conditions originating in the perinatal period	0.425	0.575
J40-J47 Chronic lower respiratory diseases	0.425	0.575
Z93 Artificial opening status	0.426	0.574
Chapter XXII Codes for special purposes	0.429	0.571
J09-J18 Influenza and pneumonia	0.429	0.571
I95-I99 Other and unspecified disorders of the circulatory system	0.430	0.570
M40-M43 Deforming dorsopathies	0.430	0.569
Z87 Personal history of other diseases and conditions	0.431	0.569
J20-J22 Other acute lower respiratory infections	0.434	0.566
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.436	0.564
I00-I02 Acute rheumatic fever	0.437	0.563
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.437	0.562
M80-M85 Disorders of bone density and structure	0.438	0.562
Chapter XII Diseases of the skin and subcutaneous tissue	0.438	0.562
I05-I09 Chronic rheumatic heart diseases	0.439	0.561
Z80 Family history of malignant neoplasm	0.442	0.558
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.442	0.557
I15 Secondary hypertension	0.443	0.557
M91-M94 Chondropathies	0.444	0.556
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.446	0.553
Z89 Acquired absence of limb	0.447	0.552
E70-E90 Metabolic disorders	0.448	0.552
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.449	0.551
I64 Stroke, not specified as haemorrhage or infarction	0.449	0.551
S90-S99 Injuries to the ankle and foot	0.449	0.551
M00-M03 Infectious arthropathies	0.450	0.549
Z72.0 Tobacco use	0.452	0.548
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.452	0.547
Z81 Family history of mental and behavioural disorders	0.454	0.546
I69 Sequelae of cerebrovascular disease	0.454	0.546
Z84 Family history of other conditions	0.454	0.546
F40-F48 Neurotic, stress-related and somatoform disorders	0.455	0.545
I13 Hypertensive heart and renal disease	0.455	0.545
M86-M90 Other osteopathies	0.456	0.544
Z97 Presence of other devices	0.456	0.544
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.457	0.543
Z94 Transplanted organ and tissue status	0.457	0.542
Z98 Other postsurgical states	0.458	0.542
M65-M68 Disorders of synovium and tendon	0.458	0.542
T66-T78 Other and unspecified effects of external causes	0.458	0.542
I11 Hypertensive heart disease	0.459	0.541
I73 Other peripheral vascular diseases	0.459	0.541
M13 Other arthritis	0.459	0.541
I67 Other cerebrovascular diseases	0.459	0.541
S80-S89 Injuries to the knee and lower leg	0.459	0.540
T20-T25 Burns and corrosions of external body surface, specified by site	0.461	0.539
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.463	0.537
I62 Other nontraumatic intracranial haemorrhage	0.464	0.536
M60-M63 Disorders of muscles	0.464	0.536
Z92.1 Personal history of long-term (current) use of anticoagulants	0.464	0.536
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.466	0.534
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.466	0.534
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.467	0.533
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.467	0.532
Chapter XI Diseases of the digestive system	0.468	0.532
M50-M54 Other dorsopathies	0.469	0.531
Z86.0 Personal history of other neoplasms	0.470	0.530
M06 Other rheumatoid arthritis	0.471	0.529
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.472	0.528
Z42 Follow-up care involving plastic surgery	0.473	0.527
S60-S69 Injuries to the wrist and hand	0.473	0.527
T33-T35 Frostbite	0.474	0.526
T26-T28 Burns and corrosions confined to eye and internal organs	0.474	0.526
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.474	0.526
Z13 Special screening examination for other diseases and disorders	0.476	0.524
T00-T07 Injuries involving multiple body regions	0.477	0.523
S70-S79 Injuries to the hip and thigh	0.478	0.522
T79-T79 Certain early complications of trauma	0.481	0.519
M45-M49 Spondylopathies	0.481	0.519
Z86.1 Personal history of infectious and parasitic diseases	0.481	0.519
F30-F39 Mood [affective] disorders	0.481	0.518
Z88.1 Personal history of allergy to other antibiotic agents	0.481	0.518
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.482	0.518
S40-S49 Injuries to the shoulder and upper arm	0.482	0.517
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.484	0.516
S10-S19 Injuries to the neck	0.484	0.515
I61 Intracerebral haemorrhage	0.484	0.515
T88 Other complications of surgical and medical care, not elsewhere classified	0.485	0.515
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.485	0.514
T15-T19 Effects of foreign body entering through natural orifice	0.486	0.514
I77 Other disorders of arteries and arterioles	0.487	0.513
J00-J06 Acute upper respiratory infections	0.488	0.512
I12 Hypertensive renal disease	0.488	0.511
B95-B98 Bacterial, viral and other infectious agents	0.489	0.511
I63 Cerebral infarction	0.490	0.510
B25-B34 Other viral diseases	0.491	0.509
Z96 Presence of other functional implants	0.491	0.509
Z85 Personal history of malignant neoplasm	0.491	0.509
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.492	0.508
I74 Arterial embolism and thrombosis	0.492	0.508
Z54 Convalescence	0.494	0.506
S50-S59 Injuries to the elbow and forearm	0.494	0.505
Z86.6 Personal history of diseases of the nervous system and sense organs	0.494	0.505
Z47 Other orthopaedic follow-up care	0.494	0.505
R30-R39 Symptoms and signs involving the urinary system	0.497	0.503
I72 Other aneurysm	0.497	0.503
T85 Complications of other internal prosthetic devices, implants and grafts	0.497	0.503
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.497	0.503
S20-S29 Injuries to the thorax	0.497	0.502
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.497	0.502
Z49 Care involving dialysis	0.499	0.501
Chapter VI Diseases of the nervous system	0.499	0.501
Z91 Personal history of risk-factors, not elsewhere classified	0.499	0.501
I78 Diseases of capillaries	0.499	0.501
I68 Cerebrovascular disorders in diseases classified elsewhere	0.500	0.500
Z74 Problems related to care-provider dependency	0.501	0.499
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.501	0.499
I70 Atherosclerosis	0.501	0.499
Z40 Prophylactic surgery	0.502	0.498
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.506	0.494
Z92.2 Personal history of long-term (current) use of other medicaments	0.506	0.494
M05 Seropositive rheumatoid arthritis	0.506	0.493
M10 Gout	0.507	0.492
M75 Shoulder lesions	0.508	0.492
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.508	0.492
M20 Acquired deformities of fingers and toes	0.508	0.492
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.508	0.492
Z50.1 Other physical therapy	0.508	0.491
Z53 Persons encountering health services for specifie procedures, not carried out	0.509	0.491
Z92.4 Personal history of major surgery, not elsewhere classified	0.509	0.490
H30-H36 Disorders of choroid and retina	0.510	0.490
S00 Superficial injury of head	0.510	0.490
Z52 Donors of organs and tissues	0.511	0.489
B35-B49 Mycoses	0.513	0.487
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.513	0.486
F70-F79 Mental retardation	0.514	0.486
T36-T50 Poisoning by drugs, medicaments and biological substances	0.514	0.486
J30-J39 Other diseases of upper respiratory tract	0.514	0.486
B15-B19 Viral hepatitis	0.515	0.485
J60-J70 Lung diseases due to external agents	0.515	0.485
T80 Complications following infusion, transfusion and therapeutic injection	0.516	0.484
R50-R69 General symptoms and signs	0.516	0.484
B99-B99 Other infectious diseases	0.516	0.484
B65-B83 Helminthiases	0.516	0.484
R47-R49 Symptoms and signs involving speech and voice	0.516	0.484
F99-F99 Unspecified mental disorder	0.516	0.483
I60 Subarachnoid haemorrhage	0.517	0.483
T86 Failure and rejection of transplanted organs and tissues	0.517	0.483
F80-F89 Disorders of psychological development	0.517	0.483
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.517	0.483
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.517	0.483
J80-J84 Other respiratory diseases principally affecting the interstitium	0.518	0.482
F60-F69 Disorders of adult personality and behaviour	0.519	0.481
I71 Aortic aneurysm and dissection	0.519	0.481
Z70 Counselling related to sexual attitude, behaviour and orientation	0.519	0.481
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.519	0.480
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.520	0.480
Z92.8 Personal history of other medical treatment	0.520	0.480
J95-J99 Other diseases of the respiratory system	0.521	0.479
Z44 Fitting and adjustment of external prosthetic device	0.521	0.479
Z08 Follow-up examination after treatment for malignant neoplasm	0.521	0.479
A80-A89 Viral infections of the central nervous system	0.522	0.478
Z76 Persons encountering health services in other circumstances	0.522	0.478
J18 Pneumonia, organism unspecified	0.523	0.477
J90-J94 Other diseases of pleura	0.524	0.476
Z43 Attention to artificial openings	0.524	0.476
S09 Other and unspecified injuries of head	0.525	0.475
S01 Open wound of head	0.525	0.475
H65-H75 Diseases of middle ear and mastoid	0.525	0.474
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.526	0.474
J22 Unspecified acute lower respiratory infection	0.526	0.474
H90-H95 Other disorders of ear	0.526	0.474
Z45 Adjustment and management of implanted device	0.527	0.473
T81.4 Infection following a procedure, not elsewhere classified	0.527	0.473
Z35 Supervision of high-risk pregnancy	0.527	0.473
H25-H28 Disorders of lens	0.527	0.472
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.528	0.472
T87 Complications peculiar to reattachment and amputation	0.528	0.471
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.528	0.471
A75-A79 Rickettsioses	0.528	0.471
A70-A74 Other diseases caused by chlamydiae	0.528	0.471
A20-A28 Certain zoonotic bacterial diseases	0.529	0.471
B85-B89 Pediculosis, acariasis and other infestations	0.529	0.471
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.529	0.471
Z73 Problems related to life-management difficulty	0.529	0.471
A65-A69 Other spirochaetal diseases	0.529	0.471
Z90.1 Acquired absence of breast(s)	0.529	0.471
M09 Juvenile arthritis in diseases classified elsewhere	0.529	0.470
M08 Juvenile arthritis	0.530	0.470
A15-A19 Tuberculosis	0.530	0.470
B50-B64 Protozoal diseases	0.530	0.470
Z41 Procedures for purposes other than remedying health state	0.530	0.469
B20-B24 Human immunodeficiency virus [HIV] disease	0.530	0.469
M12 Other specific arthropathies	0.531	0.469
Z86.5 Personal history of other mental and behavioural disorders	0.531	0.469
B90-B94 Sequelae of infectious and parasitic diseases	0.531	0.469
M14 Arthropathies in other diseases classified elsewhere	0.531	0.469
Chapter XV Pregnancy, childbirth and the puerperium	0.531	0.468
A50-A64 Infections with a predominantly sexual mode of transmission	0.531	0.468
F00-F09 Organic, including symptomatic, mental disorders	0.531	0.468
J47 Bronchiectasis	0.532	0.468
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.533	0.467
Z75 Problems related to medical facilities and other health care	0.533	0.467
I20-I25 Ischaemic heart diseases	0.533	0.467
Z95.2 Presence of prosthetic heart valve	0.533	0.467
Z12 Special screening examination for neoplasms	0.533	0.467
M11 Other crystal arthropathies	0.534	0.466
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.534	0.466
E50-E64 Other nutritional deficiencies	0.535	0.465
H80-H83 Diseases of inner ear	0.536	0.464
M07 Psoriatic and enteropathic arthropathies	0.536	0.464
Z92.9 Personal history of medical treatment, unspecified	0.536	0.464
Z92.5 Personal history of rehabilitation measures	0.536	0.464
Z95.8 Presence of other cardiac and vascular implants and grafts	0.537	0.463
Z11 Special screening examination for infectious and parasitic diseases	0.537	0.463
A00-A09 Intestinal infectious diseases	0.537	0.463
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.537	0.462
Z03 Medical observation and evaluation for suspected diseases and conditions	0.538	0.462
Z10 Routine general health check-up of defined subpopulation	0.539	0.461
Z92.6 Personal history of chemotherapy for neoplastic disease	0.539	0.461
E78.0 Pure hypercholesterolaemia	0.539	0.461
H53-H54 Visual disturbances and blindness	0.540	0.460
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.540	0.460
Z92.0 Personal history of contraception	0.540	0.460
Z88.2 Personal history of allergy to sulphonamides	0.540	0.460
T81.8 Other complications of procedures, not elsewhere classified	0.540	0.459
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.541	0.459
H40-H42 Glaucoma	0.541	0.458
M25 Other joint disorders, not elsewhere classified	0.542	0.458
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.542	0.458
J44 Other chronic obstructive pulmonary disease	0.543	0.457
H55-H59 Other disorders of eye and adnexa	0.543	0.457
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.543	0.456
Z88.7 Personal history of allergy to serum and vaccine	0.544	0.456
R95-R99 Ill-defined and unknown causes of mortality	0.545	0.455
I50 Heart failure	0.545	0.455
M13.9 Arthritis, unspecified	0.546	0.454
Z83.7 Family history of diseases of the digestive system	0.546	0.454
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.546	0.454
R42 Dizziness and giddiness	0.546	0.453
Z88.5 Personal history of allergy to narcotic agent	0.547	0.453
Z95.0 Presence of cardiac pacemaker	0.547	0.453
H60-H62 Diseases of external ear	0.548	0.452
M15-M19 Arthrosis	0.549	0.451
Z95.4 Presence of other heart-valve replacement	0.549	0.451
Z48 Other surgical follow-up care	0.549	0.451
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.549	0.451
M43 Other deforming dorsopathies	0.550	0.450
E40-E46 Malnutrition	0.550	0.450
Z95.1 Presence of aortocoronary bypass graft	0.550	0.450
E10-E14 Diabetes mellitus	0.550	0.449
M32 Systemic lupus erythematosus	0.551	0.449
M30 Polyarteritis nodosa and related conditions	0.552	0.448
S02 Fracture of skull and facial bones	0.552	0.448
Z92.3 Personal history of irradiation	0.552	0.447
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.553	0.447
Z04 Examination and observation for other reasons	0.553	0.447
E20-E35 Disorders of other endocrine glands	0.554	0.445
M35 Other systemic involvement of connective tissue	0.554	0.445
H43-H45 Disorders of vitreous body and globe	0.555	0.445
H46-H48 Disorders of optic nerve and visual pathways	0.555	0.445
I35 Nonrheumatic aortic valve disorders	0.556	0.444
Z87.0 Personal history of diseases of the respiratory system	0.556	0.444
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.559	0.441
M23 Internal derangement of knee	0.559	0.441
Z50.8 Care involving use of rehabilitation procedures	0.559	0.440
S07 Crushing injury of head	0.559	0.440
S04 Injury of cranial nerves	0.559	0.440
S08 Traumatic amputation of part of head	0.559	0.440
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.560	0.440
T81.3 Disruption of operation wound, not elsewhere classified	0.560	0.440
S03 Dislocation, sprain and strain of joints and ligaments of head	0.560	0.440
M24 Other specific joint derangements	0.560	0.439
M81 Osteoporosis without pathological fracture	0.561	0.439
D70-D77 Other diseases of blood and blood-forming organs	0.561	0.439
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.561	0.438
H10-H13 Disorders of conjunctiva	0.561	0.438
Z02 Examination and encounter for administrative purposes	0.562	0.438
L00-L08 Infections of the skin and subcutaneous tissue	0.562	0.438
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.562	0.438
Z88.6 Personal history of allergy to analgesic agent	0.563	0.437
Z33 Pregnant state, incidental	0.563	0.437
Z32 Pregnancy examination and test	0.563	0.437
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.563	0.436
Z88.4 Personal history of allergy to anaesthetic agent	0.564	0.436
A30-A49 Other bacterial diseases	0.564	0.436
X58-X59 Accidental exposure to other and unspecified factors	0.565	0.435
M33 Dermatopolymyositis	0.565	0.435
F41 Other anxiety disorders	0.565	0.435
Z31 Procreative management	0.565	0.435
S05 Injury of eye and orbit	0.565	0.435
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.565	0.435
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.566	0.434
Z88.3 Personal history of allergy to other anti-infective agents	0.566	0.434
Z36 Antenatal screening	0.566	0.434
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.566	0.434
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.566	0.434
I80 Phlebitis and thrombophlebitis	0.566	0.434
Z46 Fitting and adjustment of other devices	0.566	0.433
M70 Soft tissue disorders related to use, overuse and pressure	0.567	0.433
M34 Systemic sclerosis	0.567	0.433
T81.7 Vascular complications following a procedure, not elsewhere classified	0.567	0.433
Z95.3 Presence of xenogenic heart valve	0.567	0.433
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.567	0.432
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.568	0.432
M21 Other acquired deformities of limbs	0.569	0.431
I42 Cardiomyopathy	0.569	0.431
Z87.4 Personal history of diseases of the genito-urinary system	0.569	0.431
Z90.8 Acquired absence of other organs	0.569	0.431
Z83.3 Family history of diabetes mellitus	0.569	0.430
M06.9 Rheumatoid arthritis, unspecified	0.570	0.430
Q38-Q45 Other congenital malformations of the digestive system	0.570	0.430
Z37 Outcome of delivery	0.570	0.430
E87 Other disorders of fluid, electrolyte and acid-base balance	0.570	0.430
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.570	0.429
L60-L75 Disorders of skin appendages	0.571	0.429
Chapter XIV Diseases of the genitourinary system	0.571	0.429
E00-E07 Disorders of thyroid gland	0.571	0.429
S06 Intracranial injury	0.571	0.429
I44 Atrioventricular and left bundle-branch block	0.571	0.428
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.572	0.428
I33 Acute and subacute endocarditis	0.572	0.428
I38 Endocarditis, valve unspecified	0.572	0.427
Z93.9 Artificial opening status, unspecified	0.573	0.427
Z72.3 Lack of physical exercise	0.573	0.427
W20-W49 Exposure to inanimate mechanical forces	0.573	0.427
Z72.6 Gambling and betting	0.573	0.427
Z72.5 High-risk sexual behaviour	0.573	0.427
Z72.9 Problem related to lifestyle, unspecified	0.573	0.427
Z72.4 Inappropriate diet and eating habits	0.573	0.427
M31 Other necrotising vasculopathies	0.573	0.427
Z72.8 Other problems related to lifestyle	0.573	0.427
F32 Depressive episode	0.573	0.427
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.573	0.427
I73.0 Raynaud's syndrome	0.573	0.427
Y00-Y09 Assault	0.574	0.426
X50-X57 Overexertion, travel and privation	0.574	0.426
Z38 Liveborn infants according to place of birth	0.574	0.426
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.574	0.426
I95 Hypotension	0.574	0.426
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.574	0.426
M71 Other bursopathies	0.574	0.426
Z99.3 Dependence on wheelchair	0.574	0.425
Z72.2 Drug use	0.575	0.425
Z90.2 Acquired absence of lung [part of]	0.575	0.424
Z93.3 Colostomy status	0.576	0.424
J46 Status asthmaticus	0.576	0.424
R31 Unspecified haematuria	0.576	0.424
Z93.0 Tracheostomy status	0.576	0.424
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.576	0.424
I34 Nonrheumatic mitral valve disorders	0.577	0.423
R41 Other symptoms and signs involving cognitive functions and awareness	0.577	0.423
Z95.5 Presence of coronary angioplasty implant and graft	0.578	0.422
L40-L45 Papulosquamous disorders	0.578	0.422
Q80-Q89 Other congenital malformations	0.578	0.422
M22 Disorders of patella	0.578	0.422
Y60-Y69 Misadventures to patients during surgical and medical care	0.578	0.421
M73 Soft tissue disorders in diseases classified elsewhere	0.579	0.421
Z42.1 Follow-up care involving plastic surgery of breast	0.579	0.421
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.579	0.421
Z39 Postpartum care and examination	0.579	0.421
M77 Other enthesopathies	0.579	0.421
J13 Pneumonia due to Streptococcus pneumoniae	0.580	0.420
Z83.0 Family history of human immunodeficiency virus [HIV]	0.580	0.420
V10-V19 Pedal cyclist injured in transport accident	0.580	0.420
Q35-Q37 Cleft lip and cleft palate	0.580	0.419
Y35-Y36 Legal intervention and operations of war	0.580	0.419
X85-X99 Assault	0.580	0.419
W65-W74 Accidental drowning and submersion	0.580	0.419
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.580	0.419
I52 Other heart disorders in diseases classified elsewhere	0.580	0.419
I48 Atrial fibrillation and flutter	0.580	0.419
I41 Myocarditis in diseases classified elsewhere	0.580	0.419
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.580	0.419
I32 Pericarditis in diseases classified elsewhere	0.580	0.419
Q30-Q34 Congenital malformations of the respiratory system	0.581	0.419
I45 Other conduction disorders	0.581	0.419
Z93.1 Gastrostomy status	0.581	0.419
X30-X39 Exposure to forces of nature	0.581	0.419
Z83.6 Family history of diseases of the respiratory system	0.581	0.419
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.581	0.419
Z83.1 Family history of other infectious and parasitic diseases	0.581	0.419
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.581	0.419
V95-V97 Air and space transport accidents	0.581	0.419
V70-V79 Bus occupant injured in transport accident	0.581	0.419
I43 Cardiomyopathy in diseases classified elsewhere	0.581	0.419
I40 Acute myocarditis	0.581	0.419
J11 Influenza, virus not identified	0.581	0.419
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.581	0.419
V98-V99 Other and unspecified transport accidents	0.581	0.419
V90-V94 Water transport accidents	0.581	0.419
Y10-Y34 Event of undetermined intent	0.581	0.419
X00-X09 Exposure to smoke, fire and flames	0.581	0.419
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.581	0.419
M76 Enthesopathies of lower limb, excluding foot	0.581	0.419
Z50.6 Orthoptic training	0.581	0.418
Z50.3 Drug rehabilitation	0.582	0.418
W75-W84 Other accidental threats to breathing	0.582	0.418
I37 Pulmonary valve disorders	0.582	0.418
X20-X29 Contact with venomous animals and plants	0.582	0.418
X10-X19 Contact with heat and hot substances	0.582	0.418
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.582	0.418
V01-V09 Pedestrian injured in transport accident	0.582	0.418
I36 Nonrheumatic tricuspid valve disorders	0.582	0.418
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.582	0.418
Q60-Q64 Congenital malformations of the urinary system	0.582	0.417
M72 Fibroblastic disorders	0.583	0.417
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.583	0.417
Q00-Q07 Congenital malformations of the nervous system	0.583	0.417
V80-V89 Other land transport accidents	0.583	0.417
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.584	0.416
Z50.4 Psychotherapy, not elsewhere classified	0.584	0.416
Z83.5 Family history of eye and ear disorders	0.584	0.416
Z90.4 Acquired absence of other parts of digestive tract	0.584	0.416
I30 Acute pericarditis	0.584	0.416
T81.9 Unspecified complication of procedure	0.584	0.416
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.584	0.416
V40-V49 Car occupant injured in transport accident	0.584	0.415
S90 Superficial injury of ankle and foot	0.585	0.415
I15.0 Renovascular hypertension	0.585	0.415
X40-X49 Accidental poisoning by and exposure to noxious substances	0.585	0.415
I67.9 Cerebrovascular disease, unspecified	0.585	0.415
I47 Paroxysmal tachycardia	0.585	0.415
I15.9 Seconday hypertension, unspecified	0.585	0.415
W50-W64 Exposure to animate mechanical forces	0.585	0.415
V20-V29 Motorcycle rider injured in transport accident	0.585	0.415
Z90.0 Acquired absence of part of head and neck	0.585	0.415
F10 Mental and behavioural disorders due to use of alcohol	0.586	0.414
J18.9 Pneumonia, unspecified	0.586	0.414
Z50.2 Alcohol rehabilitation	0.586	0.414
I31 Other diseases of pericardium	0.586	0.414
Z34 Supervision of normal pregnancy	0.586	0.414
Q20-Q28 Congenital malformations of the circulatory system	0.586	0.414
I73.9 Peripheral vascular disease, unspecified	0.586	0.414
M85 Other disorders of bone density and structure	0.586	0.413
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.587	0.413
Z72.1 Alcohol use	0.587	0.413
P90-P96 Other disorders originating in the perinatal period	0.587	0.412
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.587	0.412
P75-P78 Digestive system disorders of fetus and newborn	0.587	0.412
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.587	0.412
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.587	0.412
P35-P39 Infections specific to the perinatal period	0.587	0.412
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.587	0.412
P05-P08 Disorders related to length of gestation and fetal growth	0.587	0.412
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.587	0.412
P10-P15 Birth trauma	0.587	0.412
Z90.6 Acquired absence of other parts of urinary tract	0.587	0.412
I27 Other pulmonary heart diseases	0.588	0.412
Q50-Q56 Congenital malformations of genital organs	0.588	0.412
X60-X84 Intentional self-harm	0.588	0.412
L20-L30 Dermatitis and eczema	0.588	0.412
J41 Simple and mucopurulent chronic bronchitis	0.588	0.412
Z99.2 Dependence on renal dialysis	0.588	0.412
Z80.5 Family history of malignant neoplasm of urinary tract	0.588	0.412
Z50.5 Speech therapy	0.588	0.412
Z80.9 Family history of malignant neoplasm, unspecified	0.589	0.411
Z80.8 Family history of malignant neoplasm of other organs or systems	0.589	0.411
Z90.3 Acquired absence of part of stomach	0.589	0.411
S92 Fracture of foot, except ankle	0.589	0.411
M94 Other disorders of cartilage	0.589	0.411
Z93.8 Other artificial opening status	0.589	0.411
Z13.9 Special screening examination, unspecified	0.589	0.411
Z90.5 Acquired absence of kidney	0.589	0.411
Z85.3 Personal history of malignant neoplasm of breast	0.589	0.410
J43 Emphysema	0.590	0.410
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.590	0.409
Z90.7 Acquired absence of genital organ(s)	0.591	0.409
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.591	0.409
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.591	0.409
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.591	0.409

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations