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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138436261
log Bayes Factor = 5.43269
Chromosome 4   position 25,332,404  (GRCh37) Explore rs138436261 on Ensembl!
Variant rs138436261 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.977 0.023 0.000
H40-H42 Glaucoma
0.973 0.027 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.971 0.029 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.971 0.029 0.000
H40 Glaucoma
0.955 0.045 0.000
O60-O75 Complications of labour and delivery
0.953 0.047 0.000
Chapter IX Diseases of the circulatory system
0.948 0.052 0.000
I60-I69 Cerebrovascular diseases
0.945 0.055 0.000
I67 Other cerebrovascular diseases
0.940 0.060 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.910 0.090 0.000
O70 Perineal laceration during delivery
0.910 0.090 0.000
I67.9 Cerebrovascular disease, unspecified
0.904 0.096 0.000
S80-S89 Injuries to the knee and lower leg
0.902 0.098 0.000
M50-M54 Other dorsopathies
0.899 0.101 0.000
H40.9 Glaucoma, unspecified
0.898 0.102 0.000
O70.0 First degree perineal laceration during delivery
0.898 0.102 0.000
H53-H54 Visual disturbances and blindness
0.890 0.110 0.000
M75 Shoulder lesions
0.884 0.116 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.881 0.119 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.880 0.120 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.878 0.122 0.000
H43-H45 Disorders of vitreous body and globe
0.876 0.124 0.000
M20-M25 Other joint disorders
0.875 0.125 0.000
Chapter V Mental and behavioural disorders
0.871 0.129 0.000
M79.6 Pain in limb
0.870 0.130 0.000
I67.8 Other specified cerebrovascular diseases
0.869 0.131 0.000
G90-G99 Other disorders of the nervous system
0.864 0.136 0.000
M77 Other enthesopathies
0.860 0.140 0.000
M79.8 Other specified soft tissue disorders
0.849 0.151 0.000
H25-H28 Disorders of lens
0.842 0.158 0.000
Chapter XX External causes of morbidity and mortality
0.838 0.162 0.000
M80-M85 Disorders of bone density and structure
0.837 0.163 0.000
O36 Maternal care for other known or suspected foetal problems
0.832 0.168 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.828 0.172 0.000
H55-H59 Other disorders of eye and adnexa
0.824 0.176 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.824 0.176 0.000
M23 Internal derangement of knee
0.824 0.176 0.000
S80 Superficial injury of lower leg
0.818 0.182 0.000
M79.0 Rheumatism, unspecified
0.817 0.182 0.000
M05-M14 Inflammatory polyarthropathies
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.812 0.188 0.000
I67.1 Cerebral aneurysm, nonruptured
0.811 0.189 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.192 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.803 0.197 0.000
H54 Blindness and low vision
0.803 0.197 0.000
M23.3 Other meniscus derangements
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
O47 False labour
0.800 0.200 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
G35 Multiple sclerosis
0.790 0.210 0.000
H40.0 Glaucoma suspect
0.788 0.212 0.000
G56 Mononeuropathies of upper limb
0.785 0.215 0.000
M75.0 Adhesive capsulitis of shoulder
0.784 0.216 0.000
O41 Other disorders of amniotic fluid and membranes
0.782 0.218 0.000
O63 Long labour
0.781 0.219 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.779 0.221 0.000
H25 Senile cataract
0.778 0.222 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.775 0.225 0.000
E10-E14 Diabetes mellitus
0.772 0.228 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.771 0.229 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.770 0.230 0.000
M72 Fibroblastic disorders
0.770 0.230 0.000
H40.2 Primary angle-closure glaucoma
0.765 0.235 0.000
O36.5 Maternal care for poor foetal growth
0.765 0.235 0.000
G51 Facial nerve disorders
0.763 0.237 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.763 0.237 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
H40.8 Other glaucoma
0.762 0.238 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.760 0.240 0.000
M79.1 Myalgia
0.760 0.240 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.758 0.242 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.758 0.242 0.000
G56.2 Lesion of ulnar nerve
0.758 0.242 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.757 0.243 0.000
H40.1 Primary open-angle glaucoma
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.754 0.246 0.000
M50 Cervical disk disorders
0.752 0.248 0.000
H20 Iridocyclitis
0.750 0.250 0.000
L20-L30 Dermatitis and eczema
0.750 0.250 0.000
O48 Prolonged pregnancy
0.747 0.253 0.000
F30-F39 Mood [affective] disorders
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
H43 Disorders of vitreous body
0.746 0.254 0.000
M51 Other intervertebral disk disorders
0.746 0.254 0.000
M77.9 Enthesopathy, unspecified
0.743 0.257 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.742 0.258 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.741 0.259 0.000
S89 Other and unspecified injuries of lower leg
0.741 0.259 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.740 0.259 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.740 0.260 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.261 0.000
G93 Other disorders of brain
0.738 0.262 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.737 0.263 0.000
E11 Non-insulin-dependent diabetes mellitus
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
O42 Premature rupture of membranes
0.733 0.266 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.733 0.267 0.000
O72 Postpartum haemorrhage
0.732 0.268 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.730 0.270 0.000
M79.66 Pain in limb (Lower leg)
0.730 0.270 0.000
H10-H13 Disorders of conjunctiva
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.726 0.274 0.000
O32.1 Maternal care for breech presentation
0.726 0.274 0.000
Chapter XIV Diseases of the genitourinary system
0.725 0.275 0.000
M79.7 Fibromyalgia
0.724 0.275 0.000
H54.7 Unspecified visual loss
0.722 0.278 0.000
E65-E68 Obesity and other hyperalimentation
0.721 0.279 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.719 0.280 0.000
S60-S69 Injuries to the wrist and hand
0.719 0.281 0.000
I67.2 Cerebral atherosclerosis
0.719 0.281 0.000
M75.3 Calcific tendinitis of shoulder
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
G30-G32 Other degenerative diseases of the nervous system
0.715 0.285 0.000
H25.1 Senile nuclear cataract
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.286 0.000
M71 Other bursopathies
0.713 0.286 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.289 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.711 0.289 0.000
H44 Disorders of globe
0.709 0.291 0.000
M24 Other specific joint derangements
0.709 0.291 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.709 0.291 0.000
I60 Subarachnoid haemorrhage
0.708 0.292 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.707 0.293 0.000
O73 Retained placenta and membranes, without haemorrhage
0.704 0.296 0.000
N60-N64 Disorders of breast
0.704 0.296 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.296 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.296 0.000
Chapter I Certain infectious and parasitic diseases
0.701 0.299 0.000
T33-T35 Frostbite
0.700 0.300 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.700 0.300 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
T00-T07 Injuries involving multiple body regions
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
S81 Open wound of lower leg
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
S80.9 Superficial injury of lower leg, unspecified
0.698 0.302 0.000
H42 Glaucoma in diseases classified elsewhere
0.697 0.303 0.000
O45 Premature separation of placenta [abruptio placentae]
0.696 0.303 0.000
O44 Placenta praevia
0.696 0.303 0.000
O43 Placental disorders
0.696 0.303 0.000
O33 Maternal care for known or suspected disproportion
0.696 0.303 0.000
O31 Complications specific to multiple gestation
0.696 0.303 0.000
O40 Polyhydramnios
0.696 0.303 0.000
M79.9 Soft tissue disorder, unspecified
0.696 0.304 0.000
M79.5 Residual foreign body in soft tissue
0.696 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.696 0.304 0.000
M79.3 Panniculitis, unspecified
0.696 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.696 0.304 0.000
L30 Other dermatitis
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.305 0.000
O00-O08 Pregnancy with abortive outcome
0.694 0.306 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.694 0.306 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.307 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.692 0.308 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.691 0.309 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.690 0.310 0.000
R47-R49 Symptoms and signs involving speech and voice
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.687 0.313 0.000
M21 Other acquired deformities of limbs
0.687 0.313 0.000
M75.5 Bursitis of shoulder
0.686 0.314 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.685 0.315 0.000
G37 Other demyelinating diseases of central nervous system
0.685 0.315 0.000
O30 Multiple gestation
0.685 0.315 0.000
H40.6 Glaucoma secondary to drugs
0.685 0.315 0.000
H40.5 Glaucoma secondary to other eye disorders
0.685 0.315 0.000
H40.4 Glaucoma secondary to eye inflammation
0.685 0.315 0.000
H40.3 Glaucoma secondary to eye trauma
0.685 0.315 0.000
M75.1 Rotator cuff syndrome
0.685 0.315 0.000
M79.67 Pain in limb (Ankle and foot)
0.684 0.315 0.000
O74 Complications of anaesthesia during labour and delivery
0.684 0.316 0.000
O71 Other obstetric trauma
0.684 0.316 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.684 0.316 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.684 0.316 0.000
O62 Abnormalities of forces of labour
0.684 0.316 0.000
O61 Failed induction of labour
0.684 0.316 0.000
O60 Preterm delivery
0.684 0.316 0.000
M77.4 Metatarsalgia
0.682 0.318 0.000
H18 Other disorders of cornea
0.681 0.319 0.000
H27 Other disorders of lens
0.680 0.320 0.000
I00-I02 Acute rheumatic fever
0.680 0.320 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.678 0.322 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.677 0.322 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.323 0.000
H21 Other disorders of iris and ciliary body
0.676 0.324 0.000
I69 Sequelae of cerebrovascular disease
0.675 0.325 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.675 0.325 0.000
N62 Hypertrophy of breast
0.675 0.325 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.674 0.326 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.674 0.326 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.674 0.326 0.000
I67.5 Moyamoya disease
0.674 0.326 0.000
I67.4 Hypertensive encephalopathy
0.674 0.326 0.000
I67.3 Progressive vascular leukoencephalopathy
0.674 0.326 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.674 0.326 0.000
S80.0 Contusion of knee
0.674 0.326 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.674 0.326 0.000
G91 Hydrocephalus
0.674 0.326 0.000
M79.60 Pain in limb (Multiple sites)
0.673 0.327 0.000
O80-O84 Delivery
0.672 0.328 0.000
F60-F69 Disorders of adult personality and behaviour
0.670 0.330 0.000
O66 Other obstructed labour
0.669 0.331 0.000
H53 Visual disturbances
0.669 0.331 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.666 0.334 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.665 0.335 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.664 0.336 0.000
O63.0 Prolonged first stage (of labour)
0.662 0.338 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.659 0.341 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.658 0.342 0.000
M80 Osteoporosis with pathological fracture
0.658 0.342 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.658 0.342 0.000
R87 Abnormal findings in specimens from female genital organs
0.658 0.342 0.000
M23.9 Internal derangement of knee, unspecified
0.657 0.343 0.000
L30.9 Dermatitis, unspecified
0.657 0.343 0.000
N20-N23 Urolithiasis
0.657 0.343 0.000
G96 Other disorders of central nervous system
0.656 0.344 0.000
H52 Disorders of refraction and accommodation
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.655 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.654 0.346 0.000
M79.62 Pain in limb (Upper arm)
0.653 0.347 0.000
L29 Pruritus
0.653 0.347 0.000
H54.4 Blindness, one eye
0.653 0.347 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.653 0.347 0.000
W20-W49 Exposure to inanimate mechanical forces
0.653 0.347 0.000
G58 Other mononeuropathies
0.653 0.347 0.000
G54 Nerve root and plexus disorders
0.653 0.347 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.653 0.347 0.000
G52 Disorders of other cranial nerves
0.653 0.347 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.653 0.347 0.000
O70.9 Perineal laceration during delivery, unspecified
0.652 0.348 0.000
O70.3 Fourth degree perineal laceration during delivery
0.652 0.348 0.000
O70.2 Third degree perineal laceration during delivery
0.652 0.348 0.000
F80-F89 Disorders of psychological development
0.652 0.348 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.652 0.348 0.000
E50-E64 Other nutritional deficiencies
0.650 0.349 0.000
E11.9 Without complications
0.650 0.350 0.000
M10 Gout
0.650 0.350 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.650 0.350 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.649 0.351 0.000
M34 Systemic sclerosis
0.649 0.351 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.648 0.352 0.000
S40 Superficial injury of shoulder and upper arm
0.648 0.352 0.000
E66 Obesity
0.648 0.352 0.000
I62 Other nontraumatic intracranial haemorrhage
0.648 0.352 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.647 0.353 0.000
S88 Traumatic amputation of lower leg
0.647 0.353 0.000
S87 Crushing injury of lower leg
0.647 0.353 0.000
S86 Injury of muscle and tendon at lower leg level
0.647 0.353 0.000
S85 Injury of blood vessels at lower leg level
0.647 0.353 0.000
S84 Injury of nerves at lower leg level
0.647 0.353 0.000
O41.0 Oligohydramnios
0.646 0.354 0.000
G57 Mononeuropathies of lower limb
0.643 0.356 0.000
O36.9 Maternal care for foetal problem, unspecified
0.643 0.357 0.000
M54 Dorsalgia
0.643 0.357 0.000
H57 Other disorders of eye and adnexa
0.642 0.358 0.000
Chapter XI Diseases of the digestive system
0.642 0.358 0.000
G20-G26 Extrapyramidal and movement disorders
0.642 0.358 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.641 0.359 0.000
G51.3 Clonic hemifacial spasm
0.640 0.360 0.000
H20.0 Acute and subacute iridocyclitis
0.639 0.361 0.000
R47 Speech disturbances, not elsewhere classified
0.638 0.362 0.000
M79.69 Pain in limb (Site unspecified)
0.638 0.362 0.000
M51.2 Other specified intervertebral disk displacement
0.637 0.363 0.000
H55 Nystagmus and other irregular eye movements
0.635 0.364 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.635 0.365 0.000
M13 Other arthritis
0.635 0.365 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.634 0.366 0.000
M75.8 Other shoulder lesions
0.634 0.366 0.000
M75.9 Shoulder lesion, unspecified
0.634 0.366 0.000
M75.2 Bicipital tendinitis
0.634 0.366 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.633 0.366 0.000
E11.4 With neurological complications
0.633 0.367 0.000
G36 Other acute disseminated demyelination
0.632 0.368 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.632 0.368 0.000
I63 Cerebral infarction
0.631 0.369 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.631 0.369 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.631 0.369 0.000
H17 Corneal scars and opacities
0.631 0.369 0.000
H16 Keratitis
0.631 0.369 0.000
H15 Disorders of sclera
0.631 0.369 0.000
R20 Disturbances of skin sensation
0.630 0.370 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.630 0.370 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.630 0.370 0.000
T87 Complications peculiar to reattachment and amputation
0.630 0.370 0.000
T86 Failure and rejection of transplanted organs and tissues
0.630 0.370 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.630 0.370 0.000
S80.8 Other superficial injuries of lower leg
0.628 0.372 0.000
M50.0 Cervical disk disorder with myelopathy
0.628 0.372 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.628 0.372 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.628 0.372 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.628 0.372 0.000
M33 Dermatopolymyositis
0.628 0.372 0.000
M32 Systemic lupus erythematosus
0.628 0.372 0.000
M30 Polyarteritis nodosa and related conditions
0.628 0.372 0.000
V10-V19 Pedal cyclist injured in transport accident
0.627 0.372 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.627 0.373 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.626 0.374 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.626 0.374 0.000
S89.9 Unspecified injury of lower leg
0.625 0.375 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.624 0.376 0.000
F70-F79 Mental retardation
0.624 0.376 0.000
M79.68 Pain in limb (Other)
0.624 0.376 0.000
M79.64 Pain in limb (Hand)
0.624 0.376 0.000
M79.63 Pain in limb (Forearm)
0.624 0.376 0.000
M79.61 Pain in limb (Shoulder region)
0.624 0.376 0.000
M06 Other rheumatoid arthritis
0.623 0.377 0.000
I05-I09 Chronic rheumatic heart diseases
0.620 0.380 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.620 0.380 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.620 0.380 0.000
G90 Disorders of autonomic nervous system
0.620 0.380 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.620 0.380 0.000
G92 Toxic encephalopathy
0.620 0.380 0.000
K70-K77 Diseases of liver
0.619 0.381 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.619 0.381 0.000
R87.6 Abnormal cytological findings
0.619 0.381 0.000
I30-I52 Other forms of heart disease
0.618 0.382 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.618 0.382 0.000
S42 Fracture of shoulder and upper arm
0.618 0.382 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.617 0.383 0.000
M77.5 Other enthesopathy of foot
0.617 0.383 0.000
M77.3 Calcaneal spur
0.617 0.383 0.000
M77.2 Periarthritis of wrist
0.617 0.383 0.000
M77.0 Medial epicondylitis
0.617 0.383 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.616 0.383 0.000
V20-V29 Motorcycle rider injured in transport accident
0.616 0.384 0.000
H25.9 Senile cataract, unspecified
0.615 0.385 0.000
H43.3 Other vitreous opacities
0.614 0.386 0.000
E66.9 Obesity, unspecified
0.613 0.387 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.612 0.387 0.000
F30 Manic episode
0.612 0.388 0.000
M23.8 Other internal derangements of knee
0.611 0.389 0.000
H25.8 Other senile cataract
0.610 0.390 0.000
M50.1 Cervical disk disorder with radiculopathy
0.610 0.390 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.608 0.391 0.000
M79.88 Other specified soft tissue disorders (Other)
0.608 0.391 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.608 0.391 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.608 0.391 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.608 0.391 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.608 0.391 0.000
M79.19 Myalgia (Site unspecified)
0.608 0.392 0.000
I70 Atherosclerosis
0.608 0.392 0.000
S50-S59 Injuries to the elbow and forearm
0.608 0.392 0.000
T88.5 Other complications of anaesthesia
0.608 0.392 0.000
O72.0 Third-stage haemorrhage
0.608 0.392 0.000
E11.5 With peripheral circulatory complications
0.607 0.393 0.000
G95 Other diseases of spinal cord
0.607 0.393 0.000
H50 Other strabismus
0.607 0.393 0.000
I71 Aortic aneurysm and dissection
0.606 0.394 0.000
H20.8 Other iridocyclitis
0.606 0.394 0.000
G61 Inflammatory polyneuropathy
0.605 0.395 0.000
G40-G47 Episodic and paroxysmal disorders
0.604 0.396 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.604 0.396 0.000
M85 Other disorders of bone density and structure
0.604 0.396 0.000
M70.4 Prepatellar bursitis
0.603 0.397 0.000
H44.0 Purulent endophthalmitis
0.602 0.397 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.602 0.398 0.000
H43.1 Vitreous haemorrhage
0.602 0.398 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.601 0.399 0.000
Y35-Y36 Legal intervention and operations of war
0.601 0.399 0.000
Y10-Y34 Event of undetermined intent
0.601 0.399 0.000
Y00-Y09 Assault
0.601 0.399 0.000
X85-X99 Assault
0.601 0.399 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.601 0.399 0.000
X50-X57 Overexertion, travel and privation
0.601 0.399 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.601 0.399 0.000
X30-X39 Exposure to forces of nature
0.601 0.399 0.000
X20-X29 Contact with venomous animals and plants
0.601 0.399 0.000
X10-X19 Contact with heat and hot substances
0.601 0.399 0.000
X00-X09 Exposure to smoke, fire and flames
0.601 0.399 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.601 0.399 0.000
W75-W84 Other accidental threats to breathing
0.601 0.399 0.000
W65-W74 Accidental drowning and submersion
0.601 0.399 0.000
W50-W64 Exposure to animate mechanical forces
0.601 0.399 0.000
V98-V99 Other and unspecified transport accidents
0.601 0.399 0.000
V95-V97 Air and space transport accidents
0.601 0.399 0.000
V90-V94 Water transport accidents
0.601 0.399 0.000
V80-V89 Other land transport accidents
0.601 0.399 0.000
V70-V79 Bus occupant injured in transport accident
0.601 0.399 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.601 0.399 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.601 0.399 0.000
V40-V49 Car occupant injured in transport accident
0.601 0.399 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.601 0.399 0.000
V01-V09 Pedestrian injured in transport accident
0.601 0.399 0.000
T51 Toxic effect of alcohol
0.601 0.399 0.000
M83 Adult osteomalacia
0.600 0.400 0.000
M82 Osteoporosis in diseases classified elsewhere
0.600 0.400 0.000
M72.2 Plantar fascial fibromatosis
0.600 0.400 0.000
N23 Unspecified renal colic
0.600 0.400 0.000
T93 Sequelae of injuries of lower limb
0.599 0.401 0.000
E11.2 With renal complications
0.598 0.402 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.598 0.402 0.000
F99 Mental disorder, not otherwise specified
0.598 0.402 0.000
R26 Abnormalities of gait and mobility
0.598 0.402 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.597 0.403 0.000
O36.6 Maternal care for excessive foetal growth
0.597 0.403 0.000
O36.4 Maternal care for intra-uterine death
0.597 0.403 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.597 0.403 0.000
O36.2 Maternal care for hydrops foetalis
0.597 0.403 0.000
O36.1 Maternal care for other isoimmunisation
0.597 0.403 0.000
E40-E46 Malnutrition
0.596 0.404 0.000
S27 Injury of other and unspecified intrathoracic organs
0.596 0.404 0.000
O63.9 Long labour, unspecified
0.596 0.404 0.000
O47.9 False labour, unspecified
0.595 0.405 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.594 0.406 0.000
O32.8 Maternal care for other malpresentation of foetus
0.594 0.406 0.000
O32.6 Maternal care for compound presentation
0.594 0.406 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.594 0.406 0.000
O32.4 Maternal care for high head at term
0.594 0.406 0.000
O32.3 Maternal care for face, brow and chin presentation
0.594 0.406 0.000
O32.2 Maternal care for transverse and oblique lie
0.594 0.406 0.000
O32.0 Maternal care for unstable lie
0.594 0.406 0.000
F33 Recurrent depressive disorder
0.593 0.407 0.000
N00-N08 Glomerular diseases
0.593 0.407 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.592 0.408 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.592 0.408 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.591 0.409 0.000
M24.0 Loose body in joint
0.591 0.409 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.590 0.409 0.000
M23.5 Chronic instability of knee
0.590 0.409 0.000
M23.1 Discoid meniscus (congenital)
0.590 0.409 0.000
M23.0 Cystic meniscus
0.590 0.409 0.000
G93.0 Cerebral cysts
0.590 0.410 0.000
W00-W19 Falls
0.589 0.411 0.000
M11 Other crystal arthropathies
0.589 0.411 0.000
R25 Abnormal involuntary movements
0.589 0.411 0.000
S20 Superficial injury of thorax
0.588 0.411 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.588 0.412 0.000
M41 Scoliosis
0.588 0.412 0.000
I65.2 Occlusion and stenosis of carotid artery
0.588 0.412 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.587 0.413 0.000
M77.1 Lateral epicondylitis
0.587 0.413 0.000
I44 Atrioventricular and left bundle-branch block
0.587 0.413 0.000
K76 Other diseases of liver
0.586 0.414 0.000
S80.7 Multiple superficial injuries of lower leg
0.586 0.414 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.586 0.414 0.000
M79.08 Rheumatism, unspecified (Other)
0.586 0.414 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.586 0.414 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.586 0.414 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.586 0.414 0.000
M79.04 Rheumatism, unspecified (Hand)
0.586 0.414 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.586 0.414 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.586 0.414 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.586 0.414 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.586 0.414 0.000
O03 Spontaneous abortion
0.586 0.414 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.585 0.414 0.000
M14 Arthropathies in other diseases classified elsewhere
0.585 0.415 0.000
M12 Other specific arthropathies
0.585 0.415 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.585 0.415 0.000
M08 Juvenile arthritis
0.585 0.415 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.584 0.415 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.583 0.417 0.000
G59.0 Diabetic mononeuropathy
0.583 0.417 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.582 0.418 0.000
Y40 Systemic antibiotics
0.582 0.418 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.582 0.418 0.000
U80 Agent resistant to penicillin and related antibiotics
0.581 0.419 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.581 0.419 0.000
F31 Bipolar affective disorder
0.580 0.420 0.000
H51 Other disorders of binocular movement
0.580 0.420 0.000
H49 Paralytic strabismus
0.580 0.420 0.000
M99 Biomechanical lesions, not elsewhere classified
0.579 0.420 0.000
M05 Seropositive rheumatoid arthritis
0.579 0.421 0.000
G93.4 Encephalopathy, unspecified
0.579 0.421 0.000
E13 Other specified diabetes mellitus
0.578 0.422 0.000
G93.9 Disorder of brain, unspecified
0.578 0.422 0.000
G51.0 Bell's palsy
0.577 0.423 0.000
O64.1 Obstructed labour due to breech presentation
0.577 0.423 0.000
S29 Other and unspecified injuries of thorax
0.576 0.424 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.576 0.424 0.000
S26 Injury of heart
0.576 0.424 0.000
S25 Injury of blood vessels of thorax
0.576 0.424 0.000
S24 Injury of nerves and spinal cord at thorax level
0.576 0.424 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.576 0.424 0.000
S21 Open wound of thorax
0.576 0.424 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.576 0.424 0.000
H54.6 Unqualified visual loss, one eye
0.576 0.424 0.000
H54.5 Low vision, one eye
0.576 0.424 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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