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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139338093
log Bayes Factor = 17.683
Chromosome 16   position 84,778,766  (GRCh37) Explore rs139338093 on Ensembl!
Variant rs139338093 is part of Cluster X0021

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
I73 Other peripheral vascular diseases
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.990 0.010 0.000
I73.9 Peripheral vascular disease, unspecified
0.990 0.010 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.986 0.014 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.980 0.020 0.000
I30-I52 Other forms of heart disease
0.978 0.022 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.977 0.023 0.000
N30-N39 Other diseases of urinary system
0.975 0.025 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.973 0.027 0.000
N10-N16 Renal tubulo-interstitial diseases
0.969 0.031 0.000
N30 Cystitis
0.966 0.034 0.000
M23 Internal derangement of knee
0.964 0.036 0.000
Chapter II Neoplasms
0.962 0.038 0.000
T81 Complications of procedures, not elsewhere classified
0.956 0.044 0.000
Chapter I Certain infectious and parasitic diseases
0.955 0.045 0.000
Chapter X Diseases of the respiratory system
0.953 0.047 0.000
M70-M79 Other soft tissue disorders
0.951 0.049 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.947 0.053 0.000
J95-J99 Other diseases of the respiratory system
0.946 0.054 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.943 0.057 0.000
M23.3 Other meniscus derangements
0.942 0.058 0.000
J98 Other respiratory disorders
0.942 0.058 0.000
I71 Aortic aneurysm and dissection
0.940 0.060 0.000
I46 Cardiac arrest
0.935 0.065 0.000
Z37 Outcome of delivery
0.935 0.065 0.000
J98.1 Pulmonary collapse
0.933 0.067 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.932 0.068 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.931 0.069 0.000
I35 Nonrheumatic aortic valve disorders
0.930 0.070 0.000
N13 Obstructive and reflux uropathy
0.926 0.074 0.000
N17-N19 Renal failure
0.924 0.076 0.000
I73.0 Raynaud's syndrome
0.922 0.078 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.921 0.079 0.000
O20 Haemorrhage in early pregnancy
0.917 0.083 0.000
C15-C26 Malignant neoplasms of digestive organs
0.916 0.084 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.910 0.090 0.000
Z37.0 Single live birth
0.908 0.092 0.000
C51-C58 Malignant neoplasms of female genital organs
0.900 0.100 0.000
O26.8 Other specified pregnancy-related conditions
0.899 0.101 0.000
Z29 Need for other prophylactic measures
0.896 0.103 0.000
O80-O84 Delivery
0.894 0.106 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.893 0.107 0.000
Y83.8 Other surgical procedures
0.891 0.109 0.000
I35.0 Aortic (valve) stenosis
0.891 0.109 0.000
M79.6 Pain in limb
0.888 0.112 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
M24 Other specific joint derangements
0.888 0.112 0.000
O60-O75 Complications of labour and delivery
0.887 0.113 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.884 0.116 0.000
M22 Disorders of patella
0.882 0.118 0.000
S00-S09 Injuries to the head
0.881 0.119 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.880 0.120 0.000
M50-M54 Other dorsopathies
0.877 0.123 0.000
I46.0 Cardiac arrest with successful resuscitation
0.875 0.125 0.000
Z34 Supervision of normal pregnancy
0.872 0.128 0.000
Z35 Supervision of high-risk pregnancy
0.870 0.130 0.000
A30-A49 Other bacterial diseases
0.869 0.131 0.000
N30.2 Other chronic cystitis
0.868 0.132 0.000
J98.4 Other disorders of lung
0.867 0.133 0.000
N13.3 Other and unspecified hydronephrosis
0.863 0.137 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.860 0.140 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.859 0.141 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.143 0.000
N18 Chronic renal failure
0.854 0.146 0.000
E70-E90 Metabolic disorders
0.854 0.146 0.000
E00-E07 Disorders of thyroid gland
0.853 0.147 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.850 0.150 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.849 0.151 0.000
I60-I69 Cerebrovascular diseases
0.847 0.153 0.000
N30.1 Interstitial cystitis (chronic)
0.847 0.153 0.000
M54 Dorsalgia
0.846 0.154 0.000
N30.9 Cystitis, unspecified
0.845 0.155 0.000
I34 Nonrheumatic mitral valve disorders
0.844 0.156 0.000
Chapter XXII Codes for special purposes
0.843 0.157 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.843 0.157 0.000
O80 Single spontaneous delivery
0.843 0.157 0.000
I77 Other disorders of arteries and arterioles
0.842 0.158 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.841 0.159 0.000
I74 Arterial embolism and thrombosis
0.840 0.160 0.000
O20.0 Threatened abortion
0.839 0.161 0.000
C56 Malignant neoplasm of ovary
0.839 0.161 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.839 0.161 0.000
N00-N08 Glomerular diseases
0.838 0.162 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.836 0.164 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.835 0.164 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.835 0.165 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.834 0.166 0.000
M80-M85 Disorders of bone density and structure
0.833 0.167 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.832 0.168 0.000
S70-S79 Injuries to the hip and thigh
0.832 0.168 0.000
S01 Open wound of head
0.831 0.169 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.830 0.170 0.000
M54.5 Low back pain
0.828 0.172 0.000
Chapter V Mental and behavioural disorders
0.827 0.173 0.000
C64-C68 Malignant neoplasms of urinary tract
0.827 0.173 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.825 0.175 0.000
N30.3 Trigonitis
0.823 0.177 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.822 0.178 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.822 0.178 0.000
B95-B98 Bacterial, viral and other infectious agents
0.820 0.180 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.820 0.180 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
M79.66 Pain in limb (Lower leg)
0.818 0.182 0.000
Z85 Personal history of malignant neoplasm
0.817 0.183 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.817 0.183 0.000
I49 Other cardiac arrhythmias
0.815 0.185 0.000
M47 Spondylosis
0.814 0.186 0.000
W20-W49 Exposure to inanimate mechanical forces
0.814 0.186 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.813 0.187 0.000
M79.67 Pain in limb (Ankle and foot)
0.810 0.190 0.000
W00-W19 Falls
0.808 0.192 0.000
Z29.2 Other prophylactic chemotherapy
0.804 0.196 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.801 0.199 0.000
M35 Other systemic involvement of connective tissue
0.801 0.199 0.000
I46.9 Cardiac arrest, unspecified
0.800 0.200 0.000
S90-S99 Injuries to the ankle and foot
0.800 0.200 0.000
I47 Paroxysmal tachycardia
0.799 0.201 0.000
J09-J18 Influenza and pneumonia
0.798 0.202 0.000
M21 Other acquired deformities of limbs
0.796 0.204 0.000
M24.1 Other articular cartilage disorders
0.795 0.205 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.206 0.000
M47.8 Other spondylosis
0.792 0.208 0.000
N13.4 Hydroureter
0.792 0.208 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.791 0.209 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.791 0.209 0.000
C18 Malignant neoplasm of colon
0.789 0.211 0.000
O80.0 Spontaneous vertex delivery
0.787 0.213 0.000
N18.3 Chronic kidney disease, stage 3
0.786 0.214 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.785 0.215 0.000
Z39 Postpartum care and examination
0.783 0.217 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.782 0.218 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.782 0.218 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.782 0.218 0.000
N30.0 Acute cystitis
0.781 0.219 0.000
Y83.6 Removal of other organ (partial) (total)
0.781 0.219 0.000
M54.57 Low back pain (Lumbosacral region)
0.781 0.219 0.000
A41 Other septicaemia
0.781 0.219 0.000
J00-J06 Acute upper respiratory infections
0.780 0.220 0.000
S40-S49 Injuries to the shoulder and upper arm
0.779 0.221 0.000
S50-S59 Injuries to the elbow and forearm
0.779 0.221 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.779 0.221 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.777 0.223 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.777 0.223 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.775 0.225 0.000
Y83.5 Amputation of limb(s)
0.775 0.225 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.773 0.227 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.773 0.227 0.000
N17 Acute renal failure
0.772 0.228 0.000
T87 Complications peculiar to reattachment and amputation
0.771 0.229 0.000
E05.9 Thyrotoxicosis, unspecified
0.769 0.231 0.000
L50-L54 Urticaria and erythema
0.769 0.231 0.000
N36 Other disorders of urethra
0.769 0.231 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.768 0.232 0.000
M25 Other joint disorders, not elsewhere classified
0.768 0.232 0.000
E86 Volume depletion
0.768 0.232 0.000
S10-S19 Injuries to the neck
0.767 0.233 0.000
I70 Atherosclerosis
0.767 0.233 0.000
N25-N29 Other disorders of kidney and ureter
0.766 0.234 0.000
I71.0 Dissection of aorta [any part]
0.766 0.234 0.000
M91-M94 Chondropathies
0.765 0.234 0.000
I67 Other cerebrovascular diseases
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.764 0.236 0.000
M86-M90 Other osteopathies
0.764 0.236 0.000
M71 Other bursopathies
0.764 0.236 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.764 0.236 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.762 0.237 0.000
N99-N99 Other disorders of the genitourinary system
0.762 0.238 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.762 0.238 0.000
C44 Other malignant neoplasms of skin
0.760 0.240 0.000
V10-V19 Pedal cyclist injured in transport accident
0.759 0.241 0.000
S01.8 Open wound of other parts of head
0.758 0.242 0.000
I36 Nonrheumatic tricuspid valve disorders
0.758 0.242 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.758 0.242 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.758 0.242 0.000
M22.2 Patellofemoral disorders
0.757 0.243 0.000
O26.9 Pregnancy-related condition, unspecified
0.756 0.244 0.000
T66-T78 Other and unspecified effects of external causes
0.755 0.245 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.755 0.245 0.000
M00-M03 Infectious arthropathies
0.755 0.245 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.755 0.245 0.000
Z22 Carrier of infectious disease
0.755 0.245 0.000
Z36 Antenatal screening
0.753 0.247 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.753 0.247 0.000
A15-A19 Tuberculosis
0.753 0.247 0.000
Z34.8 Supervision of other normal pregnancy
0.752 0.248 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.249 0.000
S20-S29 Injuries to the thorax
0.750 0.250 0.000
M31 Other necrotising vasculopathies
0.749 0.251 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.748 0.251 0.000
M34 Systemic sclerosis
0.748 0.252 0.000
I42 Cardiomyopathy
0.746 0.254 0.000
V20-V29 Motorcycle rider injured in transport accident
0.745 0.255 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.743 0.257 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.743 0.257 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.742 0.258 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.742 0.258 0.000
O41 Other disorders of amniotic fluid and membranes
0.741 0.259 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.740 0.260 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.740 0.260 0.000
C20 Malignant neoplasm of rectum
0.739 0.261 0.000
C16 Malignant neoplasm of stomach
0.738 0.262 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.738 0.262 0.000
M79.9 Soft tissue disorder, unspecified
0.735 0.265 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.733 0.267 0.000
I35.1 Aortic (valve) insufficiency
0.733 0.267 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.732 0.268 0.000
M20 Acquired deformities of fingers and toes
0.731 0.269 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.731 0.269 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.730 0.270 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.729 0.271 0.000
I20-I25 Ischaemic heart diseases
0.728 0.272 0.000
M76 Enthesopathies of lower limb, excluding foot
0.728 0.272 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
E10-E14 Diabetes mellitus
0.726 0.274 0.000
Z29.8 Other specified prophylactic measures
0.726 0.274 0.000
S01.0 Open wound of scalp
0.723 0.277 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.722 0.278 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.722 0.278 0.000
M47.82 Other spondylosis (Cervical region)
0.722 0.278 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.721 0.279 0.000
C18.7 Sigmoid colon
0.721 0.279 0.000
O00-O08 Pregnancy with abortive outcome
0.721 0.279 0.000
A00-A09 Intestinal infectious diseases
0.720 0.280 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.720 0.280 0.000
O16 Unspecified maternal hypertension
0.720 0.280 0.000
I67.9 Cerebrovascular disease, unspecified
0.720 0.280 0.000
M77 Other enthesopathies
0.719 0.281 0.000
Z90.7 Acquired absence of genital organ(s)
0.719 0.281 0.000
M54.56 Low back pain (Lumbar region)
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
O23 Infections of genito-urinary tract in pregnancy
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
N10 Acute tubulo-interstitial nephritis
0.716 0.284 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.716 0.284 0.000
N03 Chronic nephritic syndrome
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
I73.8 Other specified peripheral vascular diseases
0.715 0.285 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
I34.0 Mitral (valve) insufficiency
0.714 0.286 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.713 0.287 0.000
Z89 Acquired absence of limb
0.713 0.287 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.712 0.288 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.711 0.289 0.000
O21 Excessive vomiting in pregnancy
0.709 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.708 0.292 0.000
Y83.0 Surgical operation with transplant of whole organ
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.707 0.293 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.707 0.293 0.000
T86 Failure and rejection of transplanted organs and tissues
0.707 0.293 0.000
O29 Complications of anaesthesia during pregnancy
0.707 0.293 0.000
O28 Abnormal findings on antenatal screening of mother
0.707 0.293 0.000
O24 Diabetes mellitus in pregnancy
0.707 0.293 0.000
O22 Venous complications in pregnancy
0.707 0.293 0.000
O25 Malnutrition in pregnancy
0.707 0.293 0.000
O72 Postpartum haemorrhage
0.706 0.294 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.706 0.294 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.705 0.294 0.000
Z29.1 Prophylactic immunotherapy
0.705 0.295 0.000
Z63 Other problems related to primary support group, including family circumstances
0.704 0.296 0.000
E83 Disorders of mineral metabolism
0.704 0.296 0.000
I51 Complications and ill-defined descriptions of heart disease
0.704 0.296 0.000
M54.50 Low back pain (Multiple sites in spine)
0.703 0.297 0.000
S70 Superficial injury of hip and thigh
0.703 0.297 0.000
M46 Other inflammatory spondylopathies
0.703 0.297 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.702 0.297 0.000
I72 Other aneurysm
0.702 0.297 0.000
Z38 Liveborn infants according to place of birth
0.702 0.298 0.000
Z32 Pregnancy examination and test
0.702 0.298 0.000
Z31 Procreative management
0.702 0.298 0.000
C53 Malignant neoplasm of cervix uteri
0.702 0.298 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.298 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.701 0.299 0.000
I48 Atrial fibrillation and flutter
0.701 0.299 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.701 0.299 0.000
I41 Myocarditis in diseases classified elsewhere
0.701 0.299 0.000
I40 Acute myocarditis
0.701 0.299 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.701 0.299 0.000
I32 Pericarditis in diseases classified elsewhere
0.701 0.299 0.000
I30 Acute pericarditis
0.701 0.299 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.701 0.299 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.701 0.299 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.701 0.299 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.700 0.300 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.700 0.300 0.000
Z29.0 Isolation
0.700 0.300 0.000
J90-J94 Other diseases of pleura
0.700 0.300 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.699 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.699 0.301 0.000
N33 Bladder disorders in diseases classified elsewhere
0.699 0.301 0.000
M47.86 Other spondylosis (Lumbar region)
0.699 0.301 0.000
Z90.3 Acquired absence of part of stomach
0.698 0.302 0.000
I45 Other conduction disorders
0.698 0.302 0.000
M35.0 Sicca syndrome [Sjogren]
0.696 0.304 0.000
A49 Bacterial infection of unspecified site
0.696 0.304 0.000
Y83.9 Surgical procedure, unspecified
0.696 0.304 0.000
C79 Secondary malignant neoplasm of other sites
0.695 0.305 0.000
M25.4 Effusion of joint
0.695 0.305 0.000
T92 Sequelae of injuries of upper limb
0.695 0.305 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.695 0.305 0.000
N15 Other renal tubulo-interstitial diseases
0.695 0.305 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.695 0.305 0.000
N11 Chronic tubulo-interstitial nephritis
0.695 0.305 0.000
O43 Placental disorders
0.694 0.306 0.000
L53 Other erythematous conditions
0.694 0.306 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.693 0.306 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.693 0.306 0.000
T93 Sequelae of injuries of lower limb
0.693 0.307 0.000
N30.4 Irradiation cystitis
0.692 0.308 0.000
L03 Cellulitis
0.692 0.308 0.000
I25 Chronic ischaemic heart disease
0.692 0.308 0.000
O47 False labour
0.691 0.308 0.000
M23.9 Internal derangement of knee, unspecified
0.691 0.309 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.691 0.309 0.000
M23.5 Chronic instability of knee
0.691 0.309 0.000
M23.1 Discoid meniscus (congenital)
0.691 0.309 0.000
M23.0 Cystic meniscus
0.691 0.309 0.000
S02 Fracture of skull and facial bones
0.691 0.309 0.000
Chapter VII Diseases of the eye and adnexa
0.691 0.309 0.000
M79.8 Other specified soft tissue disorders
0.690 0.309 0.000
M24.0 Loose body in joint
0.690 0.310 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.690 0.310 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.690 0.310 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.690 0.310 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.689 0.311 0.000
Y83.3 Surgical operation with formation of external stoma
0.689 0.311 0.000
J40-J47 Chronic lower respiratory diseases
0.689 0.311 0.000
O42 Premature rupture of membranes
0.686 0.314 0.000
I35.8 Other aortic valve disorders
0.686 0.314 0.000
T81.9 Unspecified complication of procedure
0.686 0.314 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.686 0.314 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.686 0.314 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.686 0.314 0.000
M22.8 Other disorders of patella
0.685 0.315 0.000
B99-B99 Other infectious diseases
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.315 0.000
A75-A79 Rickettsioses
0.685 0.315 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.315 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.315 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.684 0.315 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.684 0.316 0.000
F03 Unspecified dementia
0.684 0.316 0.000
L81 Other disorders of pigmentation
0.683 0.317 0.000
N18.8 Other chronic renal failure
0.682 0.318 0.000
M23.8 Other internal derangements of knee
0.682 0.318 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.318 0.000
W22 Striking against or struck by other objects
0.682 0.318 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.680 0.320 0.000
N35 Urethral stricture
0.680 0.320 0.000
N30.8 Other cystitis
0.680 0.320 0.000
Z34.0 Supervision of normal first pregnancy
0.680 0.320 0.000
M79.0 Rheumatism, unspecified
0.680 0.320 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.679 0.321 0.000
Z28 Immunisation not carried out
0.679 0.321 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.679 0.321 0.000
Z26 Need for immunisation against other single infectious diseases
0.679 0.321 0.000
Z25 Need for immunisation against other single viral diseases
0.679 0.321 0.000
Z24 Need for immunisation against certain single viral diseases
0.679 0.321 0.000
Z23 Need for immunisation against single bacterial diseases
0.679 0.321 0.000
Z20 Contact with and exposure to communicable diseases
0.679 0.321 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.679 0.321 0.000
I77.1 Stricture of artery
0.678 0.322 0.000
J96 Respiratory failure, not elsewhere classified
0.678 0.322 0.000
M79.1 Myalgia
0.678 0.322 0.000
M54.9 Dorsalgia, unspecified
0.678 0.322 0.000
T82.3 Mechanical complication of other vascular grafts
0.678 0.322 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.677 0.323 0.000
W07 Fall involving chair
0.677 0.323 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.677 0.323 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.676 0.324 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.676 0.324 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.676 0.324 0.000
O26.5 Maternal hypotension syndrome
0.676 0.324 0.000
O26.4 Herpes gestationis
0.676 0.324 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.676 0.324 0.000
O26.2 Pregnancy care of habitual aborter
0.676 0.324 0.000
O26.1 Low weight gain in pregnancy
0.676 0.324 0.000
O26.0 Excessive weight gain in pregnancy
0.676 0.324 0.000
M23.37 Other meniscus derangements-Capsular lig
0.676 0.324 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.676 0.324 0.000
M79.60 Pain in limb (Multiple sites)
0.675 0.324 0.000
J98.9 Respiratory disorder, unspecified
0.675 0.325 0.000
J98.6 Disorders of diaphragm
0.675 0.325 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.675 0.325 0.000
J98.3 Compensatory emphysema
0.675 0.325 0.000
J98.2 Interstitial emphysema
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
O80.8 Other single spontaneous delivery
0.675 0.325 0.000
Z97 Presence of other devices
0.675 0.325 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.674 0.326 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.674 0.326 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.674 0.326 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.674 0.326 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.674 0.326 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.673 0.327 0.000
C18.6 Descending colon
0.673 0.327 0.000
M22.4 Chondromalacia patellae
0.673 0.327 0.000
L20-L30 Dermatitis and eczema
0.672 0.328 0.000
I46.1 Sudden cardiac death, so described
0.671 0.329 0.000
Z37.9 Outcome of delivery unspecified
0.670 0.329 0.000
Z37.7 Other multiple births, all stillborn
0.670 0.329 0.000
Z37.6 Other multiple births, some liveborn
0.670 0.329 0.000
Z37.5 Other multiple births, all liveborn
0.670 0.329 0.000
Z37.4 Twins, both stillborn
0.670 0.329 0.000
Z37.3 Twins, one liveborn and one stillborn
0.670 0.329 0.000
Z37.1 Single stillbirth
0.670 0.329 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.670 0.330 0.000
A41.9 Septicaemia, unspecified
0.670 0.330 0.000
M72 Fibroblastic disorders
0.670 0.330 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.670 0.330 0.000
C44.6 Skin of upper limb, including shoulder
0.669 0.331 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.669 0.331 0.000
S01.2 Open wound of nose
0.669 0.331 0.000
I60 Subarachnoid haemorrhage
0.668 0.332 0.000
C80 Malignant neoplasm without specification of site
0.668 0.332 0.000
I34.1 Mitral (valve) prolapse
0.667 0.333 0.000
O44 Placenta praevia
0.665 0.335 0.000
I78 Diseases of capillaries
0.665 0.335 0.000
C54 Malignant neoplasm of corpus uteri
0.664 0.336 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.664 0.336 0.000
N13.8 Other obstructive and reflux uropathy
0.664 0.336 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.664 0.336 0.000
N13.6 Pyonephrosis
0.664 0.336 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.664 0.336 0.000
T82.1 Mechanical complication of cardiac electronic device
0.664 0.336 0.000
N17.9 Acute renal failure, unspecified
0.663 0.337 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.662 0.338 0.000
Q60-Q64 Congenital malformations of the urinary system
0.662 0.338 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.662 0.338 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.660 0.340 0.000
M79.5 Residual foreign body in soft tissue
0.660 0.340 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.660 0.340 0.000
M79.3 Panniculitis, unspecified
0.660 0.340 0.000
M79.2 Neuralgia and neuritis, unspecified
0.660 0.340 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.660 0.340 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.659 0.341 0.000
I49.8 Other specified cardiac arrhythmias
0.658 0.342 0.000
O20.8 Other haemorrhage in early pregnancy
0.658 0.342 0.000
Z39.1 Care and examination of lactating mother
0.657 0.343 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.657 0.343 0.000
C21 Malignant neoplasm of anus and anal canal
0.657 0.343 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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