TreeWAS – Variant ID: rs139704751

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.986	0.014
Chapter VI Diseases of the nervous system	0.968	0.032
Chapter IV Endocrine, nutritional and metabolic diseases	0.960	0.040
Chapter XXI Factors influencing health status and contact with health services	0.945	0.055
Chapter XII Diseases of the skin and subcutaneous tissue	0.943	0.057
Chapter XI Diseases of the digestive system	0.933	0.067
Z00-Z13 Persons encountering health services for examination and investigation	0.920	0.080
Chapter X Diseases of the respiratory system	0.917	0.083
Chapter I Certain infectious and parasitic diseases	0.917	0.083
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.913	0.086
J30-J39 Other diseases of upper respiratory tract	0.903	0.097
Z03 Medical observation and evaluation for suspected diseases and conditions	0.891	0.109
K90-K93 Other diseases of the digestive system	0.888	0.112
Chapter II Neoplasms	0.885	0.115
G40-G47 Episodic and paroxysmal disorders	0.873	0.127
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.867	0.133
Z03.4 Observation for suspected myocardial infarction	0.867	0.133
E65-E68 Obesity and other hyperalimentation	0.863	0.137
K92 Other diseases of digestive system	0.858	0.142
R94 Abnormal results of function studies	0.858	0.142
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.856	0.144
L60-L75 Disorders of skin appendages	0.855	0.145
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.850	0.150
Chapter XV Pregnancy, childbirth and the puerperium	0.846	0.154
G50-G59 Nerve, nerve root and plexus disorders	0.836	0.164
E20-E35 Disorders of other endocrine glands	0.834	0.166
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.829	0.171
L80-L99 Other disorders of the skin and subcutaneous tissue	0.828	0.172
Chapter VIII Diseases of the ear and mastoid process	0.825	0.175
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.824	0.176
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.822	0.178
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.819	0.181
R07 Pain in throat and chest	0.819	0.181
J34 Other disorders of nose and nasal sinuses	0.818	0.182
E10-E14 Diabetes mellitus	0.817	0.183
Z13 Special screening examination for other diseases and disorders	0.817	0.183
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.816	0.184
K92.0 Haematemesis	0.814	0.186
B25-B34 Other viral diseases	0.808	0.191
R13 Dysphagia	0.807	0.193
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.803	0.197
D10-D36 Benign neoplasms	0.803	0.197
R47-R49 Symptoms and signs involving speech and voice	0.801	0.199
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.799	0.201
J32 Chronic sinusitis	0.796	0.204
B95-B98 Bacterial, viral and other infectious agents	0.794	0.206
E66 Obesity	0.794	0.206
Z60 Problems related to social environment	0.792	0.208
L72 Follicular cysts of skin and subcutaneous tissue	0.792	0.208
R94.5 Abnormal results of liver function studies	0.789	0.211
J33 Nasal polyp	0.788	0.212
G40 Epilepsy	0.770	0.230
E10 Insulin-dependent diabetes mellitus	0.767	0.233
M20-M25 Other joint disorders	0.759	0.241
Z13.9 Special screening examination, unspecified	0.753	0.247
J34.8 Other specified disorders of nose and nasal sinuses	0.749	0.251
G35-G37 Demyelinating diseases of the central nervous system	0.747	0.253
Z60.2 Living alone	0.747	0.253
R07.3 Other chest pain	0.747	0.253
G43 Migraine	0.745	0.255
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.744	0.256
L91 Hypertrophic disorders of skin	0.744	0.256
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.740	0.260
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.739	0.261
B34 Viral infection of unspecified site	0.731	0.269
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.730	0.270
L40-L45 Papulosquamous disorders	0.728	0.272
J80-J84 Other respiratory diseases principally affecting the interstitium	0.727	0.273
D00-D09 In situ neoplasms	0.727	0.273
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.726	0.274
K92.2 Gastro-intestinal haemorrhage, unspecified	0.724	0.276
G20-G26 Extrapyramidal and movement disorders	0.723	0.277
E50-E64 Other nutritional deficiencies	0.720	0.280
R94.3 Abnormal results of cardiovascular function studies	0.720	0.280
D22 Melanocytic naevi	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z03.5 Observation for other suspected cardiovascular diseases	0.716	0.284
R93 Abnormal findings on diagnostic imaging of other body structures	0.716	0.284
L72.0 Epidermal cyst	0.714	0.286
K35-K38 Diseases of appendix	0.713	0.287
G56 Mononeuropathies of upper limb	0.711	0.289
J32.9 Chronic sinusitis, unspecified	0.709	0.291
Chapter V Mental and behavioural disorders	0.709	0.291
R95-R99 Ill-defined and unknown causes of mortality	0.707	0.293
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.707	0.293
K83 Other diseases of biliary tract	0.706	0.294
Chapter VII Diseases of the eye and adnexa	0.704	0.296
D37-D48 Neoplasms of uncertain or unknown behaviour	0.704	0.296
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.702	0.298
R05 Cough	0.702	0.298
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.702	0.298
O00-O08 Pregnancy with abortive outcome	0.699	0.301
K55-K64 Other diseases of intestines	0.695	0.305
L90 Atrophic disorders of skin	0.695	0.305
G70-G73 Diseases of myoneural junction and muscle	0.694	0.306
G30-G32 Other degenerative diseases of the nervous system	0.694	0.306
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.694	0.306
G00-G09 Inflammatory diseases of the central nervous system	0.694	0.306
E66.8 Other obesity	0.694	0.306
K86 Other diseases of pancreas	0.694	0.306
H65-H75 Diseases of middle ear and mastoid	0.691	0.309
R18 Ascites	0.690	0.310
E10.9 Without complications	0.689	0.311
E40-E46 Malnutrition	0.688	0.312
R12 Heartburn	0.688	0.312
R07.4 Chest pain, unspecified	0.688	0.312
K40-K46 Hernia	0.686	0.314
C50-C50 Malignant neoplasm of breast	0.685	0.315
B35-B49 Mycoses	0.685	0.315
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.685	0.315
L20-L30 Dermatitis and eczema	0.684	0.316
K50-K52 Noninfective enteritis and colitis	0.684	0.316
L91.8 Other hypertrophic disorders of skin	0.683	0.317
Chapter XIV Diseases of the genitourinary system	0.683	0.317
E66.9 Obesity, unspecified	0.683	0.317
Z87 Personal history of other diseases and conditions	0.682	0.318
Z09.8 Follow-up examination after other treatment for other conditions	0.682	0.318
S00-S09 Injuries to the head	0.681	0.319
G62 Other polyneuropathies	0.680	0.319
O94-O99 Other obstetric conditions, not elsewhere classified	0.679	0.321
E70-E90 Metabolic disorders	0.678	0.322
R30-R39 Symptoms and signs involving the urinary system	0.678	0.322
M20 Acquired deformities of fingers and toes	0.677	0.323
L50-L54 Urticaria and erythema	0.676	0.324
L10-L14 Bullous disorders	0.676	0.324
J33.9 Nasal polyp, unspecified	0.675	0.325
B34.9 Viral infection, unspecified	0.675	0.325
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.673	0.327
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.671	0.329
J00-J06 Acute upper respiratory infections	0.670	0.329
R20 Disturbances of skin sensation	0.670	0.329
G57 Mononeuropathies of lower limb	0.670	0.330
R49 Voice disturbances	0.669	0.331
K70-K77 Diseases of liver	0.668	0.332
D27 Benign neoplasm of ovary	0.667	0.333
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.667	0.333
R01 Cardiac murmurs and other cardiac sounds	0.667	0.333
L97 Ulcer of lower limb, not elsewhere classified	0.667	0.333
Z09.2 Follow-up examination after chemotherapy for other conditions	0.665	0.335
M45-M49 Spondylopathies	0.662	0.338
L72.1 Trichilemmal cyst	0.661	0.339
G90-G99 Other disorders of the nervous system	0.661	0.339
D23 Other benign neoplasms of skin	0.661	0.339
J30 Vasomotor and allergic rhinitis	0.660	0.339
R41 Other symptoms and signs involving cognitive functions and awareness	0.660	0.340
G80-G83 Cerebral palsy and other paralytic syndromes	0.660	0.340
C15-C26 Malignant neoplasms of digestive organs	0.660	0.340
Z11 Special screening examination for infectious and parasitic diseases	0.659	0.340
Z10 Routine general health check-up of defined subpopulation	0.659	0.340
A30-A49 Other bacterial diseases	0.659	0.341
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.657	0.342
J60-J70 Lung diseases due to external agents	0.657	0.342
B99-B99 Other infectious diseases	0.657	0.342
B90-B94 Sequelae of infectious and parasitic diseases	0.657	0.342
B85-B89 Pediculosis, acariasis and other infestations	0.657	0.342
B65-B83 Helminthiases	0.657	0.342
B50-B64 Protozoal diseases	0.657	0.342
B20-B24 Human immunodeficiency virus [HIV] disease	0.657	0.342
B15-B19 Viral hepatitis	0.657	0.342
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.657	0.342
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.657	0.342
A80-A89 Viral infections of the central nervous system	0.657	0.342
A75-A79 Rickettsioses	0.657	0.342
A70-A74 Other diseases caused by chlamydiae	0.657	0.342
A65-A69 Other spirochaetal diseases	0.657	0.342
A50-A64 Infections with a predominantly sexual mode of transmission	0.657	0.342
A20-A28 Certain zoonotic bacterial diseases	0.657	0.342
A15-A19 Tuberculosis	0.657	0.342
R90 Abnormal findings on diagnostic imaging of central nervous system	0.655	0.345
R92 Abnormal findings on diagnostic imaging of breast	0.655	0.345
G43.9 Migraine, unspecified	0.654	0.346
E21.3 Hyperparathyroidism, unspecified	0.652	0.348
K92.1 Melaena	0.650	0.350
G63 Polyneuropathy in diseases classified elsewhere	0.650	0.350
J95-J99 Other diseases of the respiratory system	0.650	0.350
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.649	0.351
J39 Other diseases of upper respiratory tract	0.647	0.353
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.647	0.353
J37 Chronic laryngitis and laryngotracheitis	0.647	0.353
J35 Chronic diseases of tonsils and adenoids	0.647	0.353
J36 Peritonsillar abscess	0.647	0.353
K65-K67 Diseases of peritoneum	0.641	0.359
K85 Acute pancreatitis	0.639	0.361
Z03.9 Observation for suspected disease or condition, unspecified	0.639	0.361
Z03.6 Observation for suspected toxic effect from ingested substance	0.639	0.361
Z03.3 Observation for suspected nervous system disorder	0.639	0.361
Z03.2 Observation for suspected mental and behavioural disorders	0.639	0.361
Z03.1 Observation for suspected malignant neoplasm	0.639	0.361
Z03.0 Observation for suspected tuberculosis	0.639	0.361
M25 Other joint disorders, not elsewhere classified	0.638	0.362
G40.9 Epilepsy, unspecified	0.638	0.362
E10.4 With neurological complications	0.638	0.362
K93 Disorders of other digestive organs in diseases classified elsewhere	0.636	0.364
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.635	0.365
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.635	0.365
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.635	0.365
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.635	0.365
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.635	0.365
C40-C41 Malignant neoplasms of bone and articular cartilage	0.635	0.365
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.635	0.365
L00-L08 Infections of the skin and subcutaneous tissue	0.633	0.367
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.631	0.369
E00-E07 Disorders of thyroid gland	0.630	0.370
R40 Somnolence, stupor and coma	0.629	0.371
K90 Intestinal malabsorption	0.629	0.371
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.628	0.372
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.628	0.372
G46 Vascular syndromes of brain in cerebrovascular diseases	0.626	0.374
G44 Other headache syndromes	0.626	0.374
G41 Status epilepticus	0.626	0.374
Z04 Examination and observation for other reasons	0.626	0.374
S50-S59 Injuries to the elbow and forearm	0.626	0.374
R15 Faecal incontinence	0.625	0.375
J34.3 Hypertrophy of nasal turbinates	0.624	0.376
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.622	0.378
R02 Gangrene, not elsewhere classified	0.622	0.378
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.622	0.378
G56.0 Carpal tunnel syndrome	0.619	0.381
E67 Other hyperalimentation	0.619	0.381
E68 Sequelae of hyperalimentation	0.619	0.381
E65 Localised adiposity	0.619	0.381
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.619	0.381
K58 Irritable bowel syndrome	0.619	0.381
O60-O75 Complications of labour and delivery	0.618	0.382
R07.2 Precordial pain	0.618	0.382
J90-J94 Other diseases of pleura	0.617	0.382
R14 Flatulence and related conditions	0.617	0.383
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.616	0.384
Z95 Presence of cardiac and vascular implants and grafts	0.616	0.384
Z90 Acquired absence of organs, not elsewhere classified	0.616	0.384
K92.9 Disease of digestive system, unspecified	0.615	0.384
K92.8 Other specified diseases of digestive system	0.615	0.384
R94.8 Abnormal results of function studies of other organs and systems	0.615	0.385
R94.7 Abnormal results of other endocrine function studies	0.615	0.385
R94.6 Abnormal results of thyroid function studies	0.615	0.385
R94.4 Abnormal results of kidney function studies	0.615	0.385
R94.2 Abnormal results of pulmonary function studies	0.615	0.385
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.615	0.385
R94.0 Abnormal results of function studies of central nervous system	0.615	0.385
D22.5 Melanocytic naevi of trunk	0.615	0.385
Z65 Problems related to other psychosocial circumstances	0.614	0.386
Z64 Problems related to certain psychosocial circumstances	0.614	0.386
Z63 Other problems related to primary support group, including family circumstances	0.614	0.386
Z62 Other problems related to upbringing	0.614	0.386
Z61 Problems related to negative life events in childhood	0.614	0.386
Z59 Problems related to housing and economic circumstances	0.614	0.386
Z58 Problems related to physical environment	0.614	0.386
Z57 Occupational exposure to risk-factors	0.614	0.386
Z56 Problems related to employment and unemployment	0.614	0.386
Z55 Problems related to education and literacy	0.614	0.386
L75 Apocrine sweat disorders	0.613	0.387
L74 Eccrine sweat disorders	0.613	0.387
L73 Other follicular disorders	0.613	0.387
L71 Rosacea	0.613	0.387
L70 Acne	0.613	0.387
L68 Hypertrichosis	0.613	0.387
L67 Hair colour and hair shaft abnormalities	0.613	0.387
L66 Cicatricial alopecia [scarring hair loss]	0.613	0.387
L65 Other nonscarring hair loss	0.613	0.387
L64 Androgenic alopecia	0.613	0.387
L63 Alopecia areata	0.613	0.387
L62 Nail disorders in diseases classified elsewhere	0.613	0.387
L60 Nail disorders	0.613	0.387
R04 Haemorrhage from respiratory passages	0.613	0.387
Z70-Z76 Persons encountering health services in other circumstances	0.612	0.388
G45 Transient cerebral ischaemic attacks and related syndromes	0.611	0.388
H90-H95 Other disorders of ear	0.609	0.391
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.609	0.391
R17 Unspecified jaundice	0.609	0.391
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.609	0.391
J33.0 Polyp of nasal cavity	0.609	0.391
R26 Abnormalities of gait and mobility	0.608	0.392
K81 Cholecystitis	0.607	0.393
D17 Benign lipomatous neoplasm	0.607	0.393
O85-O92 Complications predominantly related to the puerperium	0.606	0.393
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.606	0.393
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.606	0.394
J31.0 Chronic rhinitis	0.606	0.394
M05-M14 Inflammatory polyarthropathies	0.606	0.394
C64-C68 Malignant neoplasms of urinary tract	0.605	0.395
R42 Dizziness and giddiness	0.604	0.396
M20.4 Other hammer toe(s) (acquired)	0.604	0.396
S90-S99 Injuries to the ankle and foot	0.601	0.399
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.600	0.400
L90.5 Scar conditions and fibrosis of skin	0.600	0.400
G59 Mononeuropathy in diseases classified elsewhere	0.599	0.401
G58 Other mononeuropathies	0.599	0.401
G54 Nerve root and plexus disorders	0.599	0.401
G53 Cranial nerve disorders in diseases classified elsewhere	0.599	0.401
G52 Disorders of other cranial nerves	0.599	0.401
G50 Disorders of trigeminal nerve	0.599	0.401
E35 Disorders of endocrine glands in diseases classified elsewhere	0.598	0.402
E34 Other endocrine disorders	0.598	0.402
E32 Diseases of thymus	0.598	0.402
E31 Polyglandular dysfunction	0.598	0.402
E30 Disorders of puberty, not elsewhere classified	0.598	0.402
E29 Testicular dysfunction	0.598	0.402
E28 Ovarian dysfunction	0.598	0.402
E27 Other disorders of adrenal gland	0.598	0.402
E26 Hyperaldosteronism	0.598	0.402
E25 Adrenogenital disorders	0.598	0.402
E24 Cushing's syndrome	0.598	0.402
E23 Hypofunction and other disorders of pituitary gland	0.598	0.402
E22 Hyperfunction of pituitary gland	0.598	0.402
E20 Hypoparathyroidism	0.598	0.402
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.598	0.402
R91 Abnormal findings on diagnostic imaging of lung	0.597	0.403
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.596	0.403
E21.0 Primary hyperparathyroidism	0.596	0.403
E10.3 With ophthalmic complications	0.596	0.404
J32.0 Chronic maxillary sinusitis	0.596	0.404
S60-S69 Injuries to the wrist and hand	0.596	0.404
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.594	0.406
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.594	0.406
L95 Vasculitis limited to skin, not elsewhere classified	0.594	0.406
L94 Other localised connective tissue disorders	0.594	0.406
L93 Lupus erythematosus	0.594	0.406
L92 Granulomatous disorders of skin and subcutaneous tissue	0.594	0.406
L89 Decubitus ulcer	0.594	0.406
L87 Transepidermal elimination disorders	0.594	0.406
L85 Other epidermal thickening	0.594	0.406
L81 Other disorders of pigmentation	0.594	0.406
L88 Pyoderma gangrenosum	0.594	0.406
L86 Keratoderma in diseases classified elsewhere	0.594	0.406
L84 Corns and callosities	0.594	0.406
L83 Acanthosis nigricans	0.594	0.406
L80 Vitiligo	0.594	0.406
H80-H83 Diseases of inner ear	0.592	0.408
H60-H62 Diseases of external ear	0.592	0.408
N20-N23 Urolithiasis	0.591	0.409
J81 Pulmonary oedema	0.590	0.409
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.590	0.409
M91-M94 Chondropathies	0.590	0.409
M86-M90 Other osteopathies	0.590	0.409
M65-M68 Disorders of synovium and tendon	0.590	0.409
M60-M63 Disorders of muscles	0.590	0.409
M00-M03 Infectious arthropathies	0.590	0.409
M23 Internal derangement of knee	0.590	0.410
C60-C63 Malignant neoplasms of male genital organs	0.590	0.410
R21 Rash and other nonspecific skin eruption	0.589	0.410
G61 Inflammatory polyneuropathy	0.589	0.411
G60 Hereditary and idiopathic neuropathy	0.589	0.411
G64 Other disorders of peripheral nervous system	0.589	0.411
G35 Multiple sclerosis	0.589	0.411
J33.8 Other polyp of sinus	0.587	0.413
R46 Symptoms and signs involving appearance and behaviour	0.587	0.413
R45 Symptoms and signs involving emotional state	0.587	0.413
R44 Other symptoms and signs involving general sensations and perceptions	0.587	0.413
R43 Disturbances of smell and taste	0.587	0.413
R07.1 Chest pain on breathing	0.587	0.413
R07.0 Pain in throat	0.587	0.413
Z09.0 Follow-up examination after surgery for other conditions	0.586	0.414
J34.1 Cyst and mucocele of nose and nasal sinus	0.586	0.414
J34.0 Abscess, furuncle and carbuncle of nose	0.586	0.414
E13 Other specified diabetes mellitus	0.586	0.414
E12 Malnutrition-related diabetes mellitus	0.586	0.414
M40-M43 Deforming dorsopathies	0.586	0.414
Z13.8 Special screening examination for other specified diseases and disorders	0.586	0.414
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.586	0.414
Z13.5 Special screening examination for eye and ear disorders	0.586	0.414
Z13.4 Special screening examination for certain developmental disorders in childhood	0.586	0.414
Z13.3 Special screening examination for mental and behavioural disorders	0.586	0.414
Z13.2 Special screening examination for nutritional disorders	0.586	0.414
Z13.1 Special screening examination for diabetes mellitus	0.586	0.414
R23 Other skin changes	0.585	0.415
Z03.8 Observation for other suspected diseases and conditions	0.585	0.415
D07 Carcinoma in situ of other and unspecified genital organs	0.584	0.416
D22.3 Melanocytic naevi of other and unspecified parts of face	0.582	0.418
C43-C44 Melanoma and other malignant neoplasms of skin	0.581	0.418
O20-O29 Other maternal disorders predominantly related to pregnancy	0.580	0.420
G51 Facial nerve disorders	0.580	0.420
Z87.4 Personal history of diseases of the genito-urinary system	0.580	0.420
B33 Other viral diseases, not elsewhere classified	0.580	0.420
B30 Viral conjunctivitis	0.580	0.420
B27 Infectious mononucleosis	0.580	0.420
B26 Mumps	0.580	0.420
B25 Cytomegaloviral disease	0.580	0.420
G62.9 Polyneuropathy, unspecified	0.579	0.421
D24 Benign neoplasm of breast	0.579	0.421
A00-A09 Intestinal infectious diseases	0.579	0.421
Z02 Examination and encounter for administrative purposes	0.578	0.422
T36-T50 Poisoning by drugs, medicaments and biological substances	0.576	0.424
Z09.7 Follow-up examination after combined treatment for other conditions	0.575	0.424
Z09.4 Follow-up examination after treatment of fracture	0.575	0.424
Z09.3 Follow-up examination after psychotherapy	0.575	0.424
Z09.1 Follow-up examination after radiotherapy for other conditions	0.575	0.424
D36 Benign neoplasm of other and unspecified sites	0.575	0.425
D35 Benign neoplasm of other and unspecified endocrine glands	0.575	0.425
D33 Benign neoplasm of brain and other parts of central nervous system	0.575	0.425
D32 Benign neoplasm of meninges	0.575	0.425
D31 Benign neoplasm of eye and adnexa	0.575	0.425
D30 Benign neoplasm of urinary organs	0.575	0.425
D29 Benign neoplasm of male genital organs	0.575	0.425
D28 Benign neoplasm of other and unspecified female genital organs	0.575	0.425
D26 Other benign neoplasms of uterus	0.575	0.425
D21 Other benign neoplasms of connective and other soft tissue	0.575	0.425
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.575	0.425
D19 Benign neoplasm of mesothelial tissue	0.575	0.425
D16 Benign neoplasm of bone and articular cartilage	0.575	0.425
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.575	0.425
D14 Benign neoplasm of middle ear and respiratory system	0.575	0.425
D11 Benign neoplasm of major salivary glands	0.575	0.425
D10 Benign neoplasm of mouth and pharynx	0.575	0.425
D34 Benign neoplasm of thyroid gland	0.575	0.425
K86.8 Other specified diseases of pancreas	0.575	0.425
O80-O84 Delivery	0.575	0.425
M80-M85 Disorders of bone density and structure	0.575	0.425
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.574	0.425
R47 Speech disturbances, not elsewhere classified	0.574	0.425
S40-S49 Injuries to the shoulder and upper arm	0.574	0.426
R49.0 Dysphonia	0.574	0.426
G47 Sleep disorders	0.574	0.426
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.573	0.426
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.573	0.427
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.572	0.427
T79-T79 Certain early complications of trauma	0.572	0.427
T66-T78 Other and unspecified effects of external causes	0.572	0.427
T33-T35 Frostbite	0.572	0.427
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.572	0.427
T26-T28 Burns and corrosions confined to eye and internal organs	0.572	0.427
T20-T25 Burns and corrosions of external body surface, specified by site	0.572	0.427
T15-T19 Effects of foreign body entering through natural orifice	0.572	0.427
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.572	0.427
T00-T07 Injuries involving multiple body regions	0.572	0.427
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.572	0.427
S20-S29 Injuries to the thorax	0.572	0.427
S10-S19 Injuries to the neck	0.572	0.427
J34.2 Deviated nasal septum	0.572	0.428
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.571	0.429
J32.8 Other chronic sinusitis	0.570	0.429
J32.4 Chronic pansinusitis	0.570	0.429
J32.3 Chronic sphenoidal sinusitis	0.570	0.429
J32.2 Chronic ethmoidal sinusitis	0.570	0.429
J32.1 Chronic frontal sinusitis	0.570	0.429
C34 Malignant neoplasm of bronchus and lung	0.570	0.430
M47 Spondylosis	0.570	0.430
B97 Viral agents as the cause of diseases classified to other chapters	0.569	0.430
E66.2 Extreme obesity with alveolar hypoventilation	0.569	0.430
E66.1 Drug-induced obesity	0.569	0.430
E66.0 Obesity due to excess calories	0.569	0.430
G25 Other extrapyramidal and movement disorders	0.568	0.432
K83.1 Obstruction of bile duct	0.568	0.432
Z60.9 Problem related to social environment, unspecified	0.568	0.432
Z60.8 Other problems related to social environment	0.568	0.432
Z60.5 Target of perceived adverse discrimination and persecution	0.568	0.432
Z60.4 Social exclusion and rejection	0.568	0.432
Z60.3 Acculturation difficulty	0.568	0.432
Z60.1 Atypical parenting situation	0.568	0.432
Z60.0 Problems of adjustment to life-cycle transitions	0.568	0.432
K83.0 Cholangitis	0.568	0.432
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.568	0.432
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.568	0.432
L72.2 Steatocystoma multiplex	0.568	0.432
Z87.1 Personal history of diseases of the digestive system	0.567	0.433
Z93 Artificial opening status	0.566	0.434
J33.1 Polypoid sinus degeneration	0.565	0.435
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.565	0.435
L40 Psoriasis	0.563	0.436
M50-M54 Other dorsopathies	0.563	0.436
D05 Carcinoma in situ of breast	0.563	0.437
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.563	0.437
H30-H36 Disorders of choroid and retina	0.563	0.437
R79 Other abnormal findings of blood chemistry	0.563	0.437
Z90.7 Acquired absence of genital organ(s)	0.563	0.437
K56 Paralytic ileus and intestinal obstruction without hernia	0.562	0.438
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.562	0.438
K43 Ventral hernia	0.562	0.438
O00 Ectopic pregnancy	0.562	0.438
S80-S89 Injuries to the knee and lower leg	0.561	0.439
K80 Cholelithiasis	0.560	0.440
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.559	0.441
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.558	0.442
Z94 Transplanted organ and tissue status	0.556	0.444
H72 Perforation of tympanic membrane	0.555	0.445
K35 Acute appendicitis	0.555	0.445
K59 Other functional intestinal disorders	0.555	0.445
K58.9 Irritable bowel syndrome without diarrhoea	0.554	0.446
D23.3 Skin of other and unspecified parts of face	0.554	0.446
Z12 Special screening examination for neoplasms	0.553	0.446
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.553	0.447
N10-N16 Renal tubulo-interstitial diseases	0.553	0.447
M20.1 Hallux valgus (acquired)	0.553	0.447
G40.8 Other epilepsy	0.552	0.448
G40.7 Petit mal, unspecified, without grand mal seizures	0.552	0.448
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.552	0.448
G40.5 Special epileptic syndromes	0.552	0.448
G40.4 Other generalised epilepsy and epileptic syndromes	0.552	0.448
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.552	0.448
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.552	0.448
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.552	0.448
G57.6 Lesion of plantar nerve	0.551	0.449
M25.5 Pain in joint	0.551	0.449
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.551	0.449
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.550	0.450
E10.8 With unspecified complications	0.550	0.450
E10.7 With multiple complications	0.550	0.450
E10.6 With other specified complications	0.550	0.450

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations