TreeWAS – Variant ID: rs140711597

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K20-K31 Diseases of oesophagus, stomach and duodenum	0.924	0.076	0.000
K29 Gastritis and duodenitis	0.921	0.079	0.000
Chapter XI Diseases of the digestive system	0.921	0.079	0.000
K21 Gastro-oesophageal reflux disease	0.909	0.091	0.000
K29.7 Gastritis, unspecified	0.901	0.099	0.000
K70-K77 Diseases of liver	0.885	0.115	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.877	0.123	0.000
K29.6 Other gastritis	0.868	0.132	0.000
# Top node	0.866	0.134	0.000
K35-K38 Diseases of appendix	0.861	0.139	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.860	0.140	0.000
K22 Other diseases of oesophagus	0.844	0.156	0.000
Chapter VI Diseases of the nervous system	0.828	0.172	0.000
Chapter VII Diseases of the eye and adnexa	0.828	0.172	0.000
Chapter XX External causes of morbidity and mortality	0.827	0.173	0.000
Chapter I Certain infectious and parasitic diseases	0.827	0.173	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.825	0.175	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.818	0.182	0.000
Chapter VIII Diseases of the ear and mastoid process	0.805	0.195	0.000
A00-A09 Intestinal infectious diseases	0.801	0.199	0.000
K40-K46 Hernia	0.798	0.202	0.000
K29.4 Chronic atrophic gastritis	0.797	0.203	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.797	0.203	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.796	0.204	0.000
A04 Other bacterial intestinal infections	0.795	0.205	0.000
A04.8 Other specified bacterial intestinal infections	0.793	0.207	0.000
K44 Diaphragmatic hernia	0.792	0.208	0.000
K04 Diseases of pulp and periapical tissues	0.791	0.209	0.000
K70 Alcoholic liver disease	0.790	0.210	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.787	0.213	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.783	0.217	0.000
M70-M79 Other soft tissue disorders	0.778	0.222	0.000
H65-H75 Diseases of middle ear and mastoid	0.778	0.222	0.000
G62 Other polyneuropathies	0.764	0.236	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.756	0.244	0.000
K35 Acute appendicitis	0.754	0.246	0.000
H25-H28 Disorders of lens	0.754	0.246	0.000
K22.5 Diverticulum of oesophagus, acquired	0.753	0.247	0.000
Chapter V Mental and behavioural disorders	0.749	0.251	0.000
K74 Fibrosis and cirrhosis of liver	0.745	0.254	0.000
K29.0 Acute haemorrhagic gastritis	0.745	0.255	0.000
G62.9 Polyneuropathy, unspecified	0.743	0.257	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.732	0.268	0.000
H72 Perforation of tympanic membrane	0.731	0.269	0.000
K90-K93 Other diseases of the digestive system	0.731	0.269	0.000
H25 Senile cataract	0.729	0.271	0.000
M20-M25 Other joint disorders	0.726	0.274	0.000
K04.5 Chronic apical periodontitis	0.726	0.274	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.725	0.275	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.725	0.275	0.000
K29.5 Chronic gastritis, unspecified	0.724	0.276	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.720	0.280	0.000
M23 Internal derangement of knee	0.713	0.287	0.000
K73 Chronic hepatitis, not elsewhere classified	0.712	0.288	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.712	0.288	0.000
K75 Other inflammatory liver diseases	0.711	0.289	0.000
K01 Embedded and impacted teeth	0.711	0.289	0.000
H25.1 Senile nuclear cataract	0.710	0.290	0.000
K36 Other appendicitis	0.703	0.297	0.000
K65-K67 Diseases of peritoneum	0.699	0.301	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.698	0.302	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.697	0.303	0.000
K38 Other diseases of appendix	0.696	0.304	0.000
K22.7 Barrett's oesophagus	0.693	0.307	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.688	0.312	0.000
K11 Diseases of salivary glands	0.688	0.312	0.000
H10-H13 Disorders of conjunctiva	0.681	0.319	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.676	0.324	0.000
K14 Diseases of tongue	0.676	0.324	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.674	0.326	0.000
G51 Facial nerve disorders	0.669	0.331	0.000
K00 Disorders of tooth development and eruption	0.668	0.332	0.000
K70.9 Alcoholic liver disease, unspecified	0.667	0.333	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.666	0.334	0.000
K09 Cysts of oral region, not elsewhere classified	0.664	0.336	0.000
K28 Gastrojejunal ulcer	0.662	0.338	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.662	0.338	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.662	0.338	0.000
K29.9 Gastroduodenitis, unspecified	0.661	0.339	0.000
K29.2 Alcoholic gastritis	0.661	0.339	0.000
K35.9 Acute appendicitis, unspecified	0.660	0.340	0.000
Chapter XXII Codes for special purposes	0.659	0.341	0.000
K74.6 Other and unspecified cirrhosis of liver	0.659	0.341	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.653	0.347	0.000
K72 Hepatic failure, not elsewhere classified	0.651	0.348	0.000
B15-B19 Viral hepatitis	0.650	0.349	0.000
M65-M68 Disorders of synovium and tendon	0.650	0.350	0.000
V10-V19 Pedal cyclist injured in transport accident	0.650	0.350	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.649	0.351	0.000
M23.3 Other meniscus derangements	0.648	0.352	0.000
W00-W19 Falls	0.648	0.352	0.000
Chapter X Diseases of the respiratory system	0.647	0.353	0.000
H43-H45 Disorders of vitreous body and globe	0.644	0.356	0.000
M91-M94 Chondropathies	0.644	0.356	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.639	0.360	0.000
K37 Unspecified appendicitis	0.639	0.361	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.638	0.361	0.000
Y40 Systemic antibiotics	0.637	0.363	0.000
H73 Other disorders of tympanic membrane	0.635	0.365	0.000
K77 Liver disorders in diseases classified elsewhere	0.635	0.365	0.000
K71 Toxic liver disease	0.635	0.365	0.000
J95-J99 Other diseases of the respiratory system	0.634	0.366	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.632	0.368	0.000
F17.1 Harmful use	0.631	0.369	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.630	0.370	0.000
K04.8 Radicular cyst	0.630	0.370	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.629	0.371	0.000
M79.1 Myalgia	0.627	0.372	0.000
B65-B83 Helminthiases	0.627	0.373	0.000
W50-W64 Exposure to animate mechanical forces	0.625	0.375	0.000
M79.8 Other specified soft tissue disorders	0.624	0.376	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.623	0.377	0.000
K22.2 Oesophageal obstruction	0.623	0.377	0.000
Y44 Agents primarily affecting blood constituents	0.622	0.378	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.621	0.379	0.000
G70-G73 Diseases of myoneural junction and muscle	0.621	0.379	0.000
J98 Other respiratory disorders	0.620	0.380	0.000
K70.1 Alcoholic hepatitis	0.620	0.380	0.000
K26 Duodenal ulcer	0.619	0.381	0.000
K29.3 Chronic superficial gastritis	0.619	0.381	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.618	0.381	0.000
K29.8 Duodenitis	0.618	0.382	0.000
G61 Inflammatory polyneuropathy	0.618	0.382	0.000
A80-A89 Viral infections of the central nervous system	0.618	0.382	0.000
K03 Other diseases of hard tissues of teeth	0.617	0.383	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.617	0.383	0.000
K76 Other diseases of liver	0.616	0.384	0.000
M75 Shoulder lesions	0.616	0.384	0.000
X20-X29 Contact with venomous animals and plants	0.616	0.384	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.614	0.386	0.000
M40-M43 Deforming dorsopathies	0.612	0.388	0.000
G58 Other mononeuropathies	0.611	0.389	0.000
J98.1 Pulmonary collapse	0.611	0.389	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.610	0.389	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.610	0.390	0.000
M23.8 Other internal derangements of knee	0.610	0.390	0.000
H25.0 Senile incipient cataract	0.607	0.393	0.000
K10 Other diseases of jaws	0.607	0.393	0.000
K75.0 Abscess of liver	0.606	0.394	0.000
X60-X84 Intentional self-harm	0.605	0.394	0.000
K22.3 Perforation of oesophagus	0.605	0.395	0.000
K22.0 Achalasia of cardia	0.605	0.395	0.000
V80-V89 Other land transport accidents	0.605	0.395	0.000
M21 Other acquired deformities of limbs	0.604	0.395	0.000
H55-H59 Other disorders of eye and adnexa	0.604	0.396	0.000
K70.0 Alcoholic fatty liver	0.604	0.396	0.000
M24 Other specific joint derangements	0.603	0.397	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.602	0.398	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.600	0.400	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.599	0.401	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.599	0.401	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.598	0.402	0.000
K92 Other diseases of digestive system	0.595	0.405	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.595	0.405	0.000
H69 Other disorders of Eustachian tube	0.595	0.405	0.000
K08 Other disorders of teeth and supporting structures	0.594	0.406	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.594	0.406	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.593	0.406	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.593	0.407	0.000
Y35-Y36 Legal intervention and operations of war	0.593	0.407	0.000
Y10-Y34 Event of undetermined intent	0.593	0.407	0.000
Y00-Y09 Assault	0.593	0.407	0.000
X85-X99 Assault	0.593	0.407	0.000
X50-X57 Overexertion, travel and privation	0.593	0.407	0.000
X30-X39 Exposure to forces of nature	0.593	0.407	0.000
X10-X19 Contact with heat and hot substances	0.593	0.407	0.000
X00-X09 Exposure to smoke, fire and flames	0.593	0.407	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.593	0.407	0.000
W75-W84 Other accidental threats to breathing	0.593	0.407	0.000
W65-W74 Accidental drowning and submersion	0.593	0.407	0.000
V98-V99 Other and unspecified transport accidents	0.593	0.407	0.000
V95-V97 Air and space transport accidents	0.593	0.407	0.000
V90-V94 Water transport accidents	0.593	0.407	0.000
V70-V79 Bus occupant injured in transport accident	0.593	0.407	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.593	0.407	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.593	0.407	0.000
V40-V49 Car occupant injured in transport accident	0.593	0.407	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.593	0.407	0.000
V01-V09 Pedestrian injured in transport accident	0.593	0.407	0.000
B99-B99 Other infectious diseases	0.593	0.407	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.593	0.407	0.000
B50-B64 Protozoal diseases	0.593	0.407	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.593	0.407	0.000
A75-A79 Rickettsioses	0.593	0.407	0.000
A70-A74 Other diseases caused by chlamydiae	0.593	0.407	0.000
A65-A69 Other spirochaetal diseases	0.593	0.407	0.000
A20-A28 Certain zoonotic bacterial diseases	0.593	0.407	0.000
A15-A19 Tuberculosis	0.593	0.407	0.000
B25-B34 Other viral diseases	0.593	0.407	0.000
M77 Other enthesopathies	0.592	0.407	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.590	0.410	0.000
K66 Other disorders of peritoneum	0.590	0.410	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.590	0.410	0.000
H53-H54 Visual disturbances and blindness	0.589	0.411	0.000
H60-H62 Diseases of external ear	0.589	0.411	0.000
K73.9 Chronic hepatitis, unspecified	0.588	0.411	0.000
H65 Nonsuppurative otitis media	0.587	0.413	0.000
H74 Other disorders of middle ear and mastoid	0.587	0.413	0.000
M60-M63 Disorders of muscles	0.587	0.413	0.000
M00-M03 Infectious arthropathies	0.587	0.413	0.000
K70.3 Alcoholic cirrhosis of liver	0.582	0.418	0.000
K70.4 Alcoholic hepatic failure	0.582	0.418	0.000
Y52 Agents primarily affecting the cardiovascular system	0.581	0.419	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.581	0.419	0.000
H40-H42 Glaucoma	0.580	0.420	0.000
V20-V29 Motorcycle rider injured in transport accident	0.580	0.420	0.000
K01.1 Impacted teeth	0.580	0.420	0.000
K31 Other diseases of stomach and duodenum	0.579	0.421	0.000
M72 Fibroblastic disorders	0.579	0.421	0.000
K38.8 Other specified diseases of appendix	0.578	0.422	0.000
G51.0 Bell's palsy	0.577	0.423	0.000
W20-W49 Exposure to inanimate mechanical forces	0.576	0.424	0.000
G57 Mononeuropathies of lower limb	0.576	0.424	0.000
A07 Other protozoal intestinal diseases	0.574	0.426	0.000
A06 Amoebiasis	0.574	0.426	0.000
A05 Other bacterial foodborne intoxications	0.574	0.426	0.000
A03 Shigellosis	0.574	0.426	0.000
A02 Other Salmonella infections	0.574	0.426	0.000
A01 Typhoid and paratyphoid fevers	0.574	0.426	0.000
A00 Cholera	0.574	0.426	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.574	0.426	0.000
H11 Other disorders of conjunctiva	0.574	0.426	0.000
B35-B49 Mycoses	0.573	0.427	0.000
M23.5 Chronic instability of knee	0.572	0.427	0.000
K45 Other abdominal hernia	0.572	0.428	0.000
G54 Nerve root and plexus disorders	0.571	0.428	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.571	0.428	0.000
G52 Disorders of other cranial nerves	0.571	0.428	0.000
G60 Hereditary and idiopathic neuropathy	0.571	0.429	0.000
G64 Other disorders of peripheral nervous system	0.571	0.429	0.000
M65 Synovitis and tenosynovitis	0.571	0.429	0.000
K30 Dyspepsia	0.571	0.429	0.000
A04.9 Bacterial intestinal infection, unspecified	0.570	0.430	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.570	0.430	0.000
A04.4 Other intestinal Escherichia coli infections	0.570	0.430	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.570	0.430	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.570	0.430	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.570	0.430	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.570	0.430	0.000
M23.0 Cystic meniscus	0.569	0.431	0.000
K22.1 Ulcer of oesophagus	0.569	0.431	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.569	0.431	0.000
K44.1 Diaphragmatic hernia with gangrene	0.568	0.432	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.567	0.433	0.000
K04.3 Abnormal hard tissue formation in pulp	0.567	0.433	0.000
K04.2 Pulp degeneration	0.567	0.433	0.000
K04.1 Necrosis of pulp	0.567	0.433	0.000
K04.0 Pulpitis	0.567	0.433	0.000
M71 Other bursopathies	0.567	0.433	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.567	0.433	0.000
M95.0 Acquired deformity of nose	0.565	0.435	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.564	0.436	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.564	0.436	0.000
M05-M14 Inflammatory polyarthropathies	0.563	0.437	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.563	0.437	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.562	0.438	0.000
K11.9 Disease of salivary gland, unspecified	0.561	0.439	0.000
K22.4 Dyskinesia of oesophagus	0.560	0.439	0.000
H20 Iridocyclitis	0.559	0.441	0.000
K04.7 Periapical abscess without sinus	0.559	0.441	0.000
M76 Enthesopathies of lower limb, excluding foot	0.558	0.442	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.558	0.442	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.557	0.442	0.000
H70 Mastoiditis and related conditions	0.557	0.442	0.000
H68 Eustachian salpingitis and obstruction	0.557	0.442	0.000
H67 Otitis media in diseases classified elsewhere	0.557	0.442	0.000
H30-H36 Disorders of choroid and retina	0.556	0.444	0.000
H71 Cholesteatoma of middle ear	0.555	0.445	0.000
K75.4 Autoimmune hepatitis	0.554	0.446	0.000
M86-M90 Other osteopathies	0.553	0.446	0.000
G56 Mononeuropathies of upper limb	0.553	0.447	0.000
M79.18 Myalgia (Other)	0.552	0.448	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.552	0.448	0.000
Q00-Q07 Congenital malformations of the nervous system	0.551	0.448	0.000
K04.6 Periapical abscess with sinus	0.551	0.449	0.000
K14.9 Disease of tongue, unspecified	0.550	0.450	0.000
G50 Disorders of trigeminal nerve	0.550	0.450	0.000
Y44.2 Anticoagulants	0.548	0.452	0.000
H72.8 Other perforations of tympanic membrane	0.548	0.452	0.000
G62.2 Polyneuropathy due to other toxic agents	0.548	0.452	0.000
G62.1 Alcoholic polyneuropathy	0.548	0.452	0.000
G62.0 Drug-induced polyneuropathy	0.548	0.452	0.000
K01.0 Embedded teeth	0.547	0.453	0.000
K05 Gingivitis and periodontal diseases	0.546	0.453	0.000
K11.5 Sialolithiasis	0.546	0.454	0.000
H66 Suppurative and unspecified otitis media	0.544	0.456	0.000
K02 Dental caries	0.544	0.456	0.000
F45 Somatoform disorders	0.542	0.458	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.542	0.458	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.542	0.458	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.541	0.459	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.541	0.459	0.000
H27 Other disorders of lens	0.541	0.459	0.000
H02 Other disorders of eyelid	0.539	0.461	0.000
K35.3 Acute appendicitis with localized peritonitis	0.538	0.462	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.538	0.462	0.000
F41 Other anxiety disorders	0.537	0.463	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.537	0.463	0.000
F70-F79 Mental retardation	0.537	0.463	0.000
F60-F69 Disorders of adult personality and behaviour	0.537	0.463	0.000
M75.4 Impingement syndrome of shoulder	0.536	0.464	0.000
K22.9 Disease of oesophagus, unspecified	0.535	0.465	0.000
Y83.6 Removal of other organ (partial) (total)	0.535	0.465	0.000
K74.5 Biliary cirrhosis, unspecified	0.534	0.465	0.000
K74.4 Secondary biliary cirrhosis	0.534	0.465	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.534	0.465	0.000
K74.1 Hepatic sclerosis	0.534	0.465	0.000
K74.0 Hepatic fibrosis	0.534	0.465	0.000
F99-F99 Unspecified mental disorder	0.534	0.466	0.000
H25.9 Senile cataract, unspecified	0.534	0.466	0.000
H73.8 Other specified disorders of tympanic membrane	0.534	0.466	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.533	0.467	0.000
W13 Fall from, out of or through building or structure	0.533	0.467	0.000
Y83.3 Surgical operation with formation of external stoma	0.532	0.468	0.000
M79.6 Pain in limb	0.532	0.468	0.000
Y83.4 Other reconstructive surgery	0.532	0.468	0.000
F80-F89 Disorders of psychological development	0.531	0.469	0.000
K00.6 Disturbances in tooth eruption	0.530	0.470	0.000
G62.8 Other specified polyneuropathies	0.530	0.470	0.000
Y40.9 Systemic antibiotic, unspecified	0.530	0.470	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.529	0.471	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.529	0.471	0.000
M80-M85 Disorders of bone density and structure	0.528	0.472	0.001
Q60-Q64 Congenital malformations of the urinary system	0.528	0.472	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.528	0.472	0.000
H90-H95 Other disorders of ear	0.528	0.472	0.000
X59 Exposure to unspecified factor	0.528	0.472	0.000
M79.5 Residual foreign body in soft tissue	0.526	0.474	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.525	0.475	0.000
H21 Other disorders of iris and ciliary body	0.525	0.475	0.000
H72.2 Other marginal perforations of tympanic membrane	0.524	0.476	0.000
H72.1 Attic perforation of tympanic membrane	0.524	0.476	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.524	0.476	0.000
K07 Dentofacial anomalies [including malocclusion]	0.524	0.476	0.000
M21.1 Varus deformity, not elsewhere classified	0.523	0.477	0.000
K13 Other diseases of lip and oral mucosa	0.523	0.477	0.000
Y40.0 Penicillins	0.523	0.477	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.523	0.477	0.000
B17 Other acute viral hepatitis	0.522	0.477	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.523	0.477	0.000
H25.2 Senile cataract, morgagnian type	0.522	0.477	0.000
G30-G32 Other degenerative diseases of the nervous system	0.520	0.479	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.520	0.480	0.000
M34 Systemic sclerosis	0.520	0.480	0.000
M33 Dermatopolymyositis	0.520	0.480	0.000
M32 Systemic lupus erythematosus	0.520	0.480	0.000
M30 Polyarteritis nodosa and related conditions	0.520	0.480	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.520	0.480	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.520	0.480	0.000
K06.1 Gingival enlargement	0.520	0.480	0.000
K06.0 Gingival recession	0.520	0.480	0.000
Y59 Other and unspecified vaccines and biological substances	0.520	0.480	0.000
Y58 Bacterial vaccines	0.520	0.480	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.520	0.480	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.520	0.480	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.520	0.480	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.520	0.480	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.520	0.480	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.520	0.480	0.000
Y48 Anaesthetics and therapeutic gases	0.520	0.480	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.520	0.480	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.520	0.480	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.520	0.480	0.000
K27 Peptic ulcer, site unspecified	0.519	0.480	0.001
J95 Postprocedural respiratory disorders, not elsewhere classified	0.518	0.482	0.000
K09.2 Other cysts of jaw	0.518	0.482	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.518	0.482	0.000
K14.0 Glossitis	0.517	0.483	0.000
M99 Biomechanical lesions, not elsewhere classified	0.517	0.483	0.000
Y83.9 Surgical procedure, unspecified	0.515	0.485	0.000
J09-J18 Influenza and pneumonia	0.514	0.486	0.000
F40 Phobic anxiety disorders	0.514	0.486	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.513	0.487	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.513	0.487	0.000
K66.0 Peritoneal adhesions	0.513	0.487	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.513	0.487	0.000
M94 Other disorders of cartilage	0.512	0.488	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.512	0.488	0.000
W07 Fall involving chair	0.511	0.489	0.000
M23.9 Internal derangement of knee, unspecified	0.511	0.489	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.511	0.489	0.000
M23.4 Loose body in knee	0.511	0.489	0.000
M23.1 Discoid meniscus (congenital)	0.511	0.489	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.511	0.489	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.511	0.489	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.511	0.489	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.511	0.489	0.000
M79.9 Soft tissue disorder, unspecified	0.510	0.490	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.510	0.490	0.000
M79.3 Panniculitis, unspecified	0.510	0.490	0.000
M79.2 Neuralgia and neuritis, unspecified	0.510	0.490	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.510	0.490	0.000
K75.2 Nonspecific reactive hepatitis	0.510	0.490	0.000
K75.1 Phlebitis of portal vein	0.510	0.490	0.000
H18 Other disorders of cornea	0.509	0.491	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.508	0.492	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.507	0.493	0.000
K35.8 Acute appendicitis, other and unspecified	0.507	0.493	0.000
G90-G99 Other disorders of the nervous system	0.507	0.493	0.000
H05 Disorders of orbit	0.506	0.494	0.000
H72.0 Central perforation of tympanic membrane	0.506	0.494	0.000
M75.1 Rotator cuff syndrome	0.506	0.494	0.000
K42 Umbilical hernia	0.506	0.494	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.505	0.494	0.000
K26.4 Chronic or unspecified with haemorrhage	0.505	0.494	0.000
H54 Blindness and low vision	0.505	0.495	0.000
K12 Stomatitis and related lesions	0.504	0.496	0.000
K74.3 Primary biliary cirrhosis	0.502	0.498	0.000
G56.2 Lesion of ulnar nerve	0.501	0.499	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.501	0.499	0.000
G61.8 Other inflammatory polyneuropathies	0.501	0.499	0.000
K46 Unspecified abdominal hernia	0.501	0.499	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.500	0.500	0.000
Q80-Q89 Other congenital malformations	0.500	0.500	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.500	0.500	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.500	0.500	0.000
Q35-Q37 Cleft lip and cleft palate	0.500	0.500	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.500	0.500	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.500	0.500	0.000
K38.9 Disease of appendix, unspecified	0.499	0.501	0.000
K38.3 Fistula of appendix	0.499	0.501	0.000
K38.2 Diverticulum of appendix	0.499	0.501	0.000
K38.1 Appendicular concretions	0.499	0.501	0.000
K38.0 Hyperplasia of appendix	0.499	0.501	0.000
A08 Viral and other specified intestinal infections	0.499	0.501	0.000
F43 Reaction to severe stress, and adjustment disorders	0.499	0.501	0.000
H43 Disorders of vitreous body	0.498	0.502	0.000
H80-H83 Diseases of inner ear	0.498	0.502	0.000
M31 Other necrotising vasculopathies	0.497	0.503	0.000
F30-F39 Mood [affective] disorders	0.495	0.505	0.000
Y57 Other and unspecified drugs and medicaments	0.494	0.506	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.494	0.506	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.494	0.506	0.000
H17 Corneal scars and opacities	0.494	0.506	0.000
H16 Keratitis	0.494	0.506	0.000
H15 Disorders of sclera	0.494	0.506	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.493	0.506	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.493	0.507	0.000
K11.8 Other diseases of salivary glands	0.493	0.507	0.000
K11.7 Disturbances of salivary secretion	0.493	0.507	0.000
K11.6 Mucocele of salivary gland	0.493	0.507	0.000
K11.4 Fistula of salivary gland	0.493	0.507	0.000
K11.3 Abscess of salivary gland	0.493	0.507	0.000
K11.1 Hypertrophy of salivary gland	0.493	0.507	0.000
K11.0 Atrophy of salivary gland	0.493	0.507	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.493	0.507	0.000
H10 Conjunctivitis	0.492	0.508	0.000
M65.3 Trigger finger	0.490	0.510	0.000
M07 Psoriatic and enteropathic arthropathies	0.489	0.511	0.000
K92.0 Haematemesis	0.489	0.511	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.488	0.512	0.000
G35 Multiple sclerosis	0.488	0.512	0.000
K41 Femoral hernia	0.487	0.512	0.000
M79.10 Myalgia (Multiple sites)	0.486	0.514	0.000
K14.6 Glossodynia	0.485	0.515	0.000
K14.5 Plicated tongue	0.485	0.515	0.000
K14.4 Atrophy of tongue papillae	0.485	0.515	0.000
K14.3 Hypertrophy of tongue papillae	0.485	0.515	0.000
K14.2 Median rhomboid glossitis	0.485	0.515	0.000
K14.1 Geographic tongue	0.485	0.515	0.000
K72.9 Hepatic failure, unspecified	0.484	0.516	0.000
Q50-Q56 Congenital malformations of genital organs	0.484	0.516	0.000
G20-G26 Extrapyramidal and movement disorders	0.484	0.516	0.000
B80 Enterobiasis	0.483	0.516	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.483	0.516	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.483	0.516	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.483	0.516	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.483	0.516	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.483	0.516	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.483	0.516	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.483	0.516	0.000
F11 Mental and behavioural disorders due to use of opioids	0.483	0.516	0.000
M43 Other deforming dorsopathies	0.483	0.517	0.000
K09.0 Developmental odontogenic cysts	0.482	0.518	0.000
G71 Primary disorders of muscles	0.482	0.518	0.000
A30-A49 Other bacterial diseases	0.482	0.518	0.000
H44 Disorders of globe	0.480	0.520	0.000
W55 Bitten or struck by other mammals	0.480	0.520	0.000
G51.9 Disorder of facial nerve, unspecified	0.480	0.520	0.000
G51.8 Other disorders of facial nerve	0.480	0.520	0.000
G51.4 Facial myokymia	0.480	0.520	0.000
G51.3 Clonic hemifacial spasm	0.480	0.520	0.000
G51.2 Melkersson's syndrome	0.480	0.520	0.000
G51.1 Geniculate ganglionitis	0.480	0.520	0.000
K00.9 Disorder of tooth development, unspecified	0.479	0.521	0.000
K00.8 Other disorders of tooth development	0.479	0.521	0.000
K00.7 Teething syndrome	0.479	0.521	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.479	0.521	0.000
K00.4 Disturbances in tooth formation	0.479	0.521	0.000
K00.3 Mottled teeth	0.479	0.521	0.000
K00.2 Abnormalities of size and form of teeth	0.479	0.521	0.000
K00.1 Supernumerary teeth	0.479	0.521	0.000
K00.0 Anodontia	0.479	0.521	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.479	0.521	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.479	0.521	0.000
F48 Other neurotic disorders	0.477	0.523	0.000
F44 Dissociative [conversion] disorders	0.477	0.523	0.000
F42 Obsessive-compulsive disorder	0.477	0.523	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.477	0.523	0.000
H01 Other inflammation of eyelid	0.476	0.523	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations