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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs140838333
log Bayes Factor = 15.8559
Chromosome 2   position 46,460,880  (GRCh37) Explore rs140838333 on Ensembl!
Variant rs140838333 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
Z51.5 Palliative care
0.998 0.002 0.000
Z51 Other medical care
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
N60-N64 Disorders of breast
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.995 0.005 0.000
C79 Secondary malignant neoplasm of other sites
0.988 0.012 0.000
M15-M19 Arthrosis
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.987 0.013 0.000
Z86 Personal history of certain other diseases
0.987 0.013 0.000
N40-N51 Diseases of male genital organs
0.985 0.015 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.981 0.019 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.973 0.027 0.000
S80-S89 Injuries to the knee and lower leg
0.968 0.032 0.000
M20-M25 Other joint disorders
0.965 0.035 0.000
M17 Gonarthrosis [arthrosis of knee]
0.962 0.038 0.000
Z86.4 Personal history of psychoactive substance abuse
0.961 0.039 0.000
D60-D64 Aplastic and other anaemias
0.961 0.039 0.000
N63 Unspecified lump in breast
0.960 0.040 0.000
D64 Other anaemias
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.953 0.047 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.950 0.050 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.949 0.051 0.000
D64.9 Anaemia, unspecified
0.947 0.053 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.944 0.056 0.000
Z85 Personal history of malignant neoplasm
0.943 0.057 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.936 0.064 0.000
I21 Acute myocardial infarction
0.935 0.065 0.000
Z92 Personal history of medical treatment
0.934 0.066 0.000
M25.5 Pain in joint
0.932 0.068 0.000
M17.1 Other primary gonarthrosis
0.928 0.072 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
C78.7 Secondary malignant neoplasm of liver
0.922 0.078 0.000
S40-S49 Injuries to the shoulder and upper arm
0.920 0.080 0.000
N48 Other disorders of penis
0.919 0.081 0.000
C34 Malignant neoplasm of bronchus and lung
0.912 0.088 0.000
I30-I52 Other forms of heart disease
0.912 0.088 0.000
N60 Benign mammary dysplasia
0.912 0.088 0.000
Chapter XX External causes of morbidity and mortality
0.912 0.088 0.000
Z95.1 Presence of aortocoronary bypass graft
0.911 0.089 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.908 0.092 0.000
Z86.7 Personal history of diseases of the circulatory system
0.907 0.093 0.000
C64-C68 Malignant neoplasms of urinary tract
0.904 0.096 0.000
Z86.0 Personal history of other neoplasms
0.898 0.102 0.000
E70-E90 Metabolic disorders
0.897 0.103 0.000
N00-N08 Glomerular diseases
0.896 0.103 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.895 0.105 0.000
I50 Heart failure
0.894 0.106 0.000
Z92.3 Personal history of irradiation
0.891 0.109 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.891 0.109 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.891 0.109 0.000
N41 Inflammatory diseases of prostate
0.889 0.111 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.889 0.111 0.000
Z45 Adjustment and management of implanted device
0.888 0.112 0.000
C34.9 Bronchus or lung, unspecified
0.888 0.112 0.000
S82 Fracture of lower leg, including ankle
0.887 0.113 0.000
M25.56 Pain in joint (Lower leg)
0.886 0.114 0.000
I60-I69 Cerebrovascular diseases
0.886 0.114 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.882 0.118 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.882 0.118 0.000
T92 Sequelae of injuries of upper limb
0.881 0.119 0.000
M19 Other arthrosis
0.879 0.121 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.878 0.122 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.874 0.126 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.873 0.127 0.000
N64 Other disorders of breast
0.872 0.128 0.000
M25.7 Osteophyte
0.872 0.128 0.000
I50.1 Left ventricular failure
0.871 0.129 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.867 0.133 0.000
I47 Paroxysmal tachycardia
0.864 0.136 0.000
E86 Volume depletion
0.862 0.138 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.860 0.140 0.000
Z51.8 Other specified medical care
0.860 0.140 0.000
Z95.2 Presence of prosthetic heart valve
0.857 0.143 0.000
N17-N19 Renal failure
0.857 0.143 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.848 0.152 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.848 0.152 0.000
I21.4 Acute subendocardial myocardial infarction
0.847 0.153 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.838 0.162 0.000
Z40 Prophylactic surgery
0.837 0.163 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.837 0.163 0.000
M17.9 Gonarthrosis, unspecified
0.836 0.164 0.000
Chapter VIII Diseases of the ear and mastoid process
0.836 0.164 0.000
Chapter XI Diseases of the digestive system
0.835 0.165 0.000
I05-I09 Chronic rheumatic heart diseases
0.830 0.170 0.000
S90-S99 Injuries to the ankle and foot
0.830 0.170 0.000
N62 Hypertrophy of breast
0.830 0.170 0.000
Chapter I Certain infectious and parasitic diseases
0.827 0.173 0.000
Z93 Artificial opening status
0.826 0.174 0.000
N41.1 Chronic prostatitis
0.825 0.175 0.000
M18 Arthrosis of first carpometacarpal joint
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
N43 Hydrocele and spermatocele
0.824 0.176 0.000
C51-C58 Malignant neoplasms of female genital organs
0.823 0.176 0.000
I24 Other acute ischaemic heart diseases
0.822 0.178 0.000
Z51.0 Radiotherapy session
0.822 0.178 0.000
T92.1 Sequelae of fracture of arm
0.821 0.179 0.000
K70-K77 Diseases of liver
0.820 0.180 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.820 0.180 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.820 0.180 0.000
N45 Orchitis and epididymitis
0.818 0.182 0.000
S42 Fracture of shoulder and upper arm
0.817 0.183 0.000
I22 Subsequent myocardial infarction
0.815 0.185 0.000
N60.0 Solitary cyst of breast
0.814 0.186 0.000
Z84 Family history of other conditions
0.814 0.186 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.812 0.188 0.000
I63 Cerebral infarction
0.811 0.189 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.810 0.190 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.808 0.192 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.807 0.193 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.807 0.193 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.807 0.193 0.000
M24 Other specific joint derangements
0.806 0.194 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.806 0.194 0.000
L03 Cellulitis
0.805 0.195 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.802 0.198 0.000
O60-O75 Complications of labour and delivery
0.801 0.199 0.000
N48.6 Balanitis xerotica obliterans
0.801 0.199 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.800 0.200 0.000
C79.6 Secondary malignant neoplasm of ovary
0.800 0.200 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.800 0.200 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.798 0.202 0.000
N60.8 Other benign mammary dysplasias
0.798 0.202 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.797 0.203 0.000
D00-D09 In situ neoplasms
0.796 0.204 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.793 0.207 0.000
N03 Chronic nephritic syndrome
0.789 0.211 0.000
M22 Disorders of patella
0.787 0.213 0.000
M25.74 Osteophyte (Hand)
0.786 0.214 0.000
N48.2 Other inflammatory disorders of penis
0.786 0.214 0.000
Z90.7 Acquired absence of genital organ(s)
0.785 0.215 0.000
I50.9 Heart failure, unspecified
0.782 0.218 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
I63.9 Cerebral infarction, unspecified
0.780 0.220 0.000
S80 Superficial injury of lower leg
0.779 0.221 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.778 0.222 0.000
N18 Chronic renal failure
0.777 0.223 0.000
Z60 Problems related to social environment
0.777 0.223 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.775 0.225 0.000
A30-A49 Other bacterial diseases
0.775 0.225 0.000
M19.9 Arthrosis, unspecified
0.775 0.225 0.000
Z46 Fitting and adjustment of other devices
0.774 0.226 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.773 0.227 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.773 0.227 0.000
K75 Other inflammatory liver diseases
0.773 0.227 0.000
I47.1 Supraventricular tachycardia
0.771 0.229 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.768 0.232 0.000
M91-M94 Chondropathies
0.767 0.233 0.000
Z47 Other orthopaedic follow-up care
0.765 0.235 0.000
I25.2 Old myocardial infarction
0.765 0.235 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.763 0.237 0.000
I25.5 Ischaemic cardiomyopathy
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.762 0.238 0.000
C78.0 Secondary malignant neoplasm of lung
0.762 0.238 0.000
M70-M79 Other soft tissue disorders
0.761 0.239 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.760 0.240 0.000
M25.52 Pain in joint (Upper arm)
0.760 0.240 0.000
M25.77 Osteophyte (Ankle and foot)
0.757 0.243 0.000
Z92.8 Personal history of other medical treatment
0.756 0.244 0.000
E00-E07 Disorders of thyroid gland
0.754 0.246 0.000
I60 Subarachnoid haemorrhage
0.754 0.246 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.754 0.246 0.000
M25.57 Pain in joint (Ankle and foot)
0.754 0.246 0.000
S82.4 Fracture of fibula alone
0.753 0.247 0.000
C50-C50 Malignant neoplasm of breast
0.753 0.247 0.000
S42.2 Fracture of upper end of humerus
0.753 0.247 0.000
K35-K38 Diseases of appendix
0.752 0.248 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.751 0.249 0.000
Z42 Follow-up care involving plastic surgery
0.751 0.249 0.000
L03.1 Cellulitis of other parts of limb
0.750 0.250 0.000
Z51.2 Other chemotherapy
0.749 0.251 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.749 0.251 0.000
Z45.8 Adjustment and management of other implanted devices
0.748 0.252 0.000
D50-D53 Nutritional anaemias
0.748 0.252 0.000
N48.4 Impotence of organic origin
0.748 0.252 0.000
S83.2 Tear of meniscus, current
0.747 0.252 0.000
C77.5 Intrapelvic lymph nodes
0.747 0.253 0.000
N10-N16 Renal tubulo-interstitial diseases
0.746 0.254 0.000
D61 Other aplastic anaemias
0.745 0.255 0.000
M65-M68 Disorders of synovium and tendon
0.744 0.256 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.744 0.256 0.000
K74 Fibrosis and cirrhosis of liver
0.743 0.257 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.743 0.257 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.742 0.258 0.000
Z81 Family history of mental and behavioural disorders
0.740 0.260 0.000
C56 Malignant neoplasm of ovary
0.738 0.262 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.738 0.262 0.000
N30-N39 Other diseases of urinary system
0.737 0.263 0.000
Z49 Care involving dialysis
0.736 0.264 0.000
M21 Other acquired deformities of limbs
0.736 0.264 0.000
N60.2 Fibroadenosis of breast
0.735 0.265 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.735 0.265 0.000
C67 Malignant neoplasm of bladder
0.734 0.266 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.732 0.268 0.000
S82.3 Fracture of lower end of tibia
0.731 0.269 0.000
I25.3 Aneurysm of heart
0.730 0.270 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.730 0.270 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.729 0.271 0.000
N64.8 Other specified disorders of breast
0.727 0.272 0.000
A41 Other septicaemia
0.727 0.273 0.000
N40 Hyperplasia of prostate
0.727 0.273 0.000
D80-D89 Certain disorders involving the immune mechanism
0.726 0.274 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.725 0.275 0.000
I45 Other conduction disorders
0.724 0.275 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.724 0.276 0.000
C80 Malignant neoplasm without specification of site
0.724 0.276 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.724 0.276 0.000
S82.2 Fracture of shaft of tibia
0.723 0.277 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.722 0.278 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.722 0.278 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.722 0.278 0.000
Y00-Y09 Assault
0.721 0.279 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.721 0.279 0.000
S20-S29 Injuries to the thorax
0.720 0.280 0.000
M34 Systemic sclerosis
0.718 0.282 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.718 0.282 0.000
M25.50 Pain in joint (Multiple sites)
0.717 0.283 0.000
N17 Acute renal failure
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M35 Other systemic involvement of connective tissue
0.716 0.284 0.000
E20-E35 Disorders of other endocrine glands
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
M25.76 Osteophyte (Lower leg)
0.715 0.285 0.000
M19.94 Arthrosis, unspecified (Hand)
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
Y86 Sequelae of other accidents
0.714 0.286 0.000
E16 Other disorders of pancreatic internal secretion
0.713 0.287 0.000
Z93.3 Colostomy status
0.713 0.287 0.000
N99-N99 Other disorders of the genitourinary system
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.712 0.288 0.000
Z90.1 Acquired absence of breast(s)
0.712 0.288 0.000
N03.9 Unspecified
0.712 0.288 0.000
M80-M85 Disorders of bone density and structure
0.712 0.288 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.711 0.289 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.710 0.290 0.000
C34.3 Lower lobe, bronchus or lung
0.710 0.290 0.000
Z85.6 Personal history of leukaemia
0.709 0.291 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.709 0.291 0.000
N02 Recurrent and persistent haematuria
0.709 0.291 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.708 0.292 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.708 0.292 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.708 0.292 0.000
N43.3 Hydrocele, unspecified
0.708 0.292 0.000
Z51.3 Blood transfusion without reported diagnosis
0.708 0.292 0.000
M15 Polyarthrosis
0.708 0.292 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.708 0.292 0.000
Z60.2 Living alone
0.708 0.292 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
S42.20 Fracture of upper end of humerus (closed)
0.706 0.294 0.000
Z29 Need for other prophylactic measures
0.706 0.294 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.706 0.294 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.706 0.294 0.000
N46 Male infertility
0.706 0.294 0.000
N44 Torsion of testis
0.706 0.294 0.000
Z95.0 Presence of cardiac pacemaker
0.706 0.294 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.704 0.296 0.000
N18.3 Chronic kidney disease, stage 3
0.704 0.296 0.000
N61 Inflammatory disorders of breast
0.703 0.296 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.703 0.297 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.703 0.297 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.703 0.297 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.703 0.297 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.702 0.298 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.702 0.298 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.701 0.299 0.000
Z95.3 Presence of xenogenic heart valve
0.701 0.299 0.000
Z95.4 Presence of other heart-valve replacement
0.699 0.301 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.699 0.301 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.699 0.301 0.000
M19.0 Primary arthrosis of other joints
0.698 0.302 0.000
C79.2 Secondary malignant neoplasm of skin
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.698 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.303 0.000
K09 Cysts of oral region, not elsewhere classified
0.696 0.304 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.696 0.304 0.000
Z56 Problems related to employment and unemployment
0.695 0.304 0.000
L89 Decubitus ulcer
0.694 0.306 0.000
S88 Traumatic amputation of lower leg
0.694 0.306 0.000
S87 Crushing injury of lower leg
0.694 0.306 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.306 0.000
S85 Injury of blood vessels at lower leg level
0.694 0.306 0.000
S84 Injury of nerves at lower leg level
0.694 0.306 0.000
C77.8 Lymph nodes of multiple regions
0.694 0.306 0.000
E80.4 Gilbert's syndrome
0.693 0.307 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M30 Polyarteritis nodosa and related conditions
0.692 0.308 0.000
C77.4 Inguinal and lower limb lymph nodes
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.690 0.310 0.000
M17.5 Other secondary gonarthrosis
0.690 0.310 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.690 0.310 0.000
M17.3 Other posttraumatic gonarthrosis
0.690 0.310 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.690 0.310 0.000
E03 Other hypothyroidism
0.689 0.311 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.689 0.311 0.000
M31 Other necrotising vasculopathies
0.689 0.311 0.000
C91 Lymphoid leukaemia
0.689 0.311 0.000
I35 Nonrheumatic aortic valve disorders
0.688 0.312 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.688 0.312 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.687 0.313 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.686 0.314 0.000
N04 Nephrotic syndrome
0.686 0.314 0.000
E40-E46 Malnutrition
0.685 0.314 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.685 0.315 0.000
Z84.2 Family history of other diseases of the genito-urinary system
0.685 0.315 0.000
T79-T79 Certain early complications of trauma
0.685 0.315 0.000
N64.4 Mastodynia
0.684 0.315 0.000
K76 Other diseases of liver
0.684 0.316 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.684 0.316 0.000
M86-M90 Other osteopathies
0.684 0.316 0.000
D51 Vitamin B12 deficiency anaemia
0.684 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.684 0.316 0.000
D64.8 Other specified anaemias
0.683 0.317 0.000
D64.4 Congenital dyserythropoietic anaemia
0.683 0.317 0.000
D64.3 Other sideroblastic anaemias
0.683 0.317 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.683 0.317 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.683 0.317 0.000
D64.0 Hereditary sideroblastic anaemia
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
M25.2 Flail joint
0.683 0.317 0.000
M25.1 Fistula of joint
0.683 0.317 0.000
M25.0 Haemarthrosis
0.683 0.317 0.000
N32 Other disorders of bladder
0.682 0.318 0.000
H90-H95 Other disorders of ear
0.682 0.318 0.000
C34.0 Main bronchus
0.681 0.319 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.680 0.320 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.680 0.320 0.000
C32 Malignant neoplasm of larynx
0.680 0.320 0.000
C31 Malignant neoplasm of accessory sinuses
0.680 0.320 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.680 0.320 0.000
C37 Malignant neoplasm of thymus
0.680 0.320 0.000
C33 Malignant neoplasm of trachea
0.680 0.320 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.678 0.322 0.000
Z92.0 Personal history of contraception
0.677 0.322 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.323 0.000
L03.0 Cellulitis of finger and toe
0.676 0.324 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.676 0.324 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.676 0.324 0.000
M16 Coxarthrosis [arthrosis of hip]
0.676 0.324 0.000
Z47.8 Other specified orthopaedic follow-up care
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
Z93.6 Other artificial openings of urinary tract status
0.674 0.325 0.000
I07 Rheumatic tricuspid valve diseases
0.674 0.326 0.000
M22.4 Chondromalacia patellae
0.674 0.326 0.000
M50-M54 Other dorsopathies
0.674 0.326 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.673 0.327 0.000
O63 Long labour
0.672 0.328 0.000
Y84.2 Radiological procedure and radiotherapy
0.672 0.328 0.000
N18.9 Chronic renal failure, unspecified
0.672 0.328 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.671 0.328 0.000
M25.8 Other specified joint disorders
0.671 0.329 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.670 0.329 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.670 0.329 0.000
Z97 Presence of other devices
0.670 0.330 0.000
Z92.9 Personal history of medical treatment, unspecified
0.669 0.330 0.000
Z92.5 Personal history of rehabilitation measures
0.669 0.330 0.000
Y84.6 Urinary catheterisation
0.669 0.331 0.000
S89 Other and unspecified injuries of lower leg
0.669 0.331 0.000
M25.59 Pain in joint (Site unspecified)
0.668 0.331 0.000
M25.58 Pain in joint (Other)
0.668 0.331 0.000
C78.2 Secondary malignant neoplasm of pleura
0.668 0.332 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.668 0.332 0.000
S70-S79 Injuries to the hip and thigh
0.667 0.332 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.667 0.333 0.000
H80-H83 Diseases of inner ear
0.666 0.334 0.000
S81 Open wound of lower leg
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
Z90.8 Acquired absence of other organs
0.665 0.335 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.665 0.335 0.000
K75.8 Other specified inflammatory liver diseases
0.665 0.335 0.000
X60-X84 Intentional self-harm
0.664 0.336 0.000
K75.4 Autoimmune hepatitis
0.664 0.336 0.000
S82.8 Fractures of other parts of lower leg
0.664 0.336 0.000
Z22 Carrier of infectious disease
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.337 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.337 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.662 0.338 0.000
L50-L54 Urticaria and erythema
0.662 0.338 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.661 0.339 0.000
Z45.1 Adjustment and management of infusion pump
0.661 0.339 0.000
I46 Cardiac arrest
0.661 0.339 0.000
M40-M43 Deforming dorsopathies
0.660 0.340 0.000
O46.9 Antepartum haemorrhage, unspecified
0.660 0.340 0.000
S48 Traumatic amputation of shoulder and upper arm
0.659 0.340 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.659 0.340 0.000
S44 Injury of nerves at shoulder and upper arm level
0.659 0.340 0.000
S41 Open wound of shoulder and upper arm
0.659 0.340 0.000
S47 Crushing injury of shoulder and upper arm
0.659 0.340 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.659 0.341 0.000
N48.9 Disorder of penis, unspecified
0.659 0.341 0.000
N48.5 Ulcer of penis
0.659 0.341 0.000
N48.3 Priapism
0.659 0.341 0.000
C77.0 Lymph nodes of head, face and neck
0.659 0.341 0.000
O00-O08 Pregnancy with abortive outcome
0.659 0.341 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.658 0.342 0.000
I05 Rheumatic mitral valve diseases
0.658 0.342 0.000
K04 Diseases of pulp and periapical tissues
0.658 0.342 0.000
I22.8 Subsequent myocardial infarction of other sites
0.658 0.342 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.657 0.343 0.000
S82.40 Fracture of fibula alone (closed)
0.657 0.343 0.000
N64.1 Fat necrosis of breast
0.657 0.343 0.000
N48.1 Balanoposthitis
0.657 0.343 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.656 0.344 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.655 0.345 0.000
S40 Superficial injury of shoulder and upper arm
0.655 0.345 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.655 0.345 0.000
C34.8 Overlapping lesion of bronchus and lung
0.654 0.346 0.000
C34.2 Middle lobe, bronchus or lung
0.654 0.346 0.000
I52 Other heart disorders in diseases classified elsewhere
0.654 0.346 0.000
I48 Atrial fibrillation and flutter
0.654 0.346 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.654 0.346 0.000
I41 Myocarditis in diseases classified elsewhere
0.654 0.346 0.000
I40 Acute myocarditis
0.654 0.346 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.654 0.346 0.000
I37 Pulmonary valve disorders
0.654 0.346 0.000
I36 Nonrheumatic tricuspid valve disorders
0.654 0.346 0.000
I32 Pericarditis in diseases classified elsewhere
0.654 0.346 0.000
I30 Acute pericarditis
0.654 0.346 0.000
N60.9 Benign mammary dysplasia, unspecified
0.654 0.346 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.654 0.346 0.000
Y10-Y34 Event of undetermined intent
0.654 0.346 0.000
X85-X99 Assault
0.654 0.346 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.654 0.346 0.000
X50-X57 Overexertion, travel and privation
0.654 0.346 0.000
X30-X39 Exposure to forces of nature
0.654 0.346 0.000
X10-X19 Contact with heat and hot substances
0.654 0.346 0.000
X00-X09 Exposure to smoke, fire and flames
0.654 0.346 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.346 0.000
W75-W84 Other accidental threats to breathing
0.654 0.346 0.000
W65-W74 Accidental drowning and submersion
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.346 0.000
V98-V99 Other and unspecified transport accidents
0.654 0.346 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
V90-V94 Water transport accidents
0.654 0.346 0.000
V80-V89 Other land transport accidents
0.654 0.346 0.000
V70-V79 Bus occupant injured in transport accident
0.654 0.346 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.346 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.654 0.346 0.000
V40-V49 Car occupant injured in transport accident
0.654 0.346 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.654 0.346 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.346 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.652 0.348 0.000
L08 Other local infections of skin and subcutaneous tissue
0.652 0.348 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.652 0.348 0.000
I38 Endocarditis, valve unspecified
0.652 0.348 0.000
N48.0 Leukoplakia of penis
0.651 0.349 0.000
L10-L14 Bullous disorders
0.651 0.349 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.650 0.350 0.000
O47 False labour
0.650 0.350 0.000
K74.6 Other and unspecified cirrhosis of liver
0.650 0.350 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.648 0.352 0.000
C66 Malignant neoplasm of ureter
0.648 0.352 0.000
C65 Malignant neoplasm of renal pelvis
0.648 0.352 0.000
I47.2 Ventricular tachycardia
0.648 0.352 0.000
Z90.5 Acquired absence of kidney
0.647 0.353 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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