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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs140900046
log Bayes Factor = 0.434575
Chromosome 19   position 56,111,075  (GRCh37) Explore rs140900046 on Ensembl!
Variant rs140900046 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.621 0.379 0.000
Chapter VII Diseases of the eye and adnexa
0.621 0.379 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.612 0.388 0.000
Chapter VI Diseases of the nervous system
0.606 0.394 0.000
H25-H28 Disorders of lens
0.599 0.401 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.596 0.404 0.000
H26 Other cataract
0.589 0.411 0.000
S20-S29 Injuries to the thorax
0.589 0.411 0.000
Chapter V Mental and behavioural disorders
0.581 0.419 0.000
H26.9 Cataract, unspecified
0.565 0.435 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.551 0.449 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.547 0.453 0.000
H30-H36 Disorders of choroid and retina
0.545 0.455 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.536 0.464 0.000
F30-F39 Mood [affective] disorders
0.535 0.465 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.534 0.466 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.533 0.467 0.000
Chapter I Certain infectious and parasitic diseases
0.533 0.467 0.000
M15-M19 Arthrosis
0.531 0.469 0.000
E10-E14 Diabetes mellitus
0.528 0.472 0.000
M05-M14 Inflammatory polyarthropathies
0.528 0.472 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.527 0.473 0.000
M45-M49 Spondylopathies
0.527 0.473 0.000
S40-S49 Injuries to the shoulder and upper arm
0.526 0.474 0.000
M19 Other arthrosis
0.522 0.478 0.000
M19.9 Arthrosis, unspecified
0.516 0.484 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.515 0.485 0.000
G20-G26 Extrapyramidal and movement disorders
0.513 0.487 0.000
F32 Depressive episode
0.512 0.488 0.000
H26.4 After-cataract
0.507 0.493 0.000
S22.4 Multiple fractures of ribs
0.506 0.493 0.000
H43-H45 Disorders of vitreous body and globe
0.504 0.496 0.000
E11 Non-insulin-dependent diabetes mellitus
0.502 0.498 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.501 0.499 0.000
Chapter XXII Codes for special purposes
0.501 0.499 0.000
G90-G99 Other disorders of the nervous system
0.499 0.501 0.000
F32.9 Depressive episode, unspecified
0.496 0.504 0.000
Chapter IX Diseases of the circulatory system
0.494 0.506 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.492 0.508 0.000
G56 Mononeuropathies of upper limb
0.490 0.510 0.000
I30-I52 Other forms of heart disease
0.488 0.512 0.000
S00-S09 Injuries to the head
0.488 0.512 0.000
H36 Retinal disorders in diseases classified elsewhere
0.487 0.513 0.000
M50-M54 Other dorsopathies
0.484 0.516 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.484 0.516 0.000
M47 Spondylosis
0.483 0.517 0.000
H26.8 Other specified cataract
0.481 0.519 0.000
S27 Injury of other and unspecified intrathoracic organs
0.479 0.521 0.000
M80-M85 Disorders of bone density and structure
0.478 0.522 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.476 0.524 0.000
S22.40 Multiple fractures of ribs (closed)
0.475 0.525 0.000
S20 Superficial injury of thorax
0.474 0.526 0.000
S42 Fracture of shoulder and upper arm
0.473 0.527 0.000
S80-S89 Injuries to the knee and lower leg
0.471 0.529 0.000
S32 Fracture of lumbar spine and pelvis
0.468 0.532 0.000
G30-G32 Other degenerative diseases of the nervous system
0.465 0.535 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.465 0.535 0.000
Chapter XX External causes of morbidity and mortality
0.463 0.537 0.000
A30-A49 Other bacterial diseases
0.462 0.538 0.000
H55-H59 Other disorders of eye and adnexa
0.462 0.538 0.000
G56.0 Carpal tunnel syndrome
0.461 0.539 0.000
E50-E64 Other nutritional deficiencies
0.461 0.539 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.460 0.540 0.000
T66-T78 Other and unspecified effects of external causes
0.458 0.542 0.000
H50 Other strabismus
0.458 0.542 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.457 0.543 0.000
S90-S99 Injuries to the ankle and foot
0.456 0.543 0.000
H10-H13 Disorders of conjunctiva
0.456 0.544 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.455 0.544 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.455 0.545 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.454 0.546 0.000
S22.0 Fracture of thoracic vertebra
0.454 0.546 0.000
I42 Cardiomyopathy
0.454 0.546 0.000
E11.3 With ophthalmic complications
0.452 0.548 0.000
M10 Gout
0.452 0.548 0.000
H53-H54 Visual disturbances and blindness
0.450 0.550 0.000
E11.2 With renal complications
0.449 0.551 0.000
I38 Endocarditis, valve unspecified
0.448 0.552 0.000
G20 Parkinson's disease
0.446 0.554 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.445 0.554 0.000
H36.0 Diabetic retinopathy
0.446 0.554 0.000
M40-M43 Deforming dorsopathies
0.442 0.558 0.000
T79-T79 Certain early complications of trauma
0.442 0.558 0.000
M13 Other arthritis
0.441 0.559 0.000
I35 Nonrheumatic aortic valve disorders
0.441 0.559 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.439 0.561 0.000
T33-T35 Frostbite
0.439 0.561 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.439 0.561 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.439 0.561 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.439 0.561 0.000
T00-T07 Injuries involving multiple body regions
0.439 0.561 0.000
S10-S19 Injuries to the neck
0.439 0.561 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.437 0.563 0.000
G70-G73 Diseases of myoneural junction and muscle
0.434 0.566 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.434 0.566 0.000
E10 Insulin-dependent diabetes mellitus
0.434 0.566 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.432 0.568 0.000
M86-M90 Other osteopathies
0.432 0.568 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.429 0.570 0.000
H27 Other disorders of lens
0.429 0.570 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.428 0.572 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.427 0.572 0.000
M91-M94 Chondropathies
0.427 0.572 0.000
M60-M63 Disorders of muscles
0.427 0.572 0.000
M00-M03 Infectious arthropathies
0.427 0.572 0.000
F99-F99 Unspecified mental disorder
0.427 0.572 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.427 0.573 0.000
M47.8 Other spondylosis
0.425 0.575 0.000
I42.9 Cardiomyopathy, unspecified
0.424 0.576 0.000
S70-S79 Injuries to the hip and thigh
0.424 0.576 0.000
H21 Other disorders of iris and ciliary body
0.423 0.576 0.000
S50-S59 Injuries to the elbow and forearm
0.423 0.577 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.423 0.577 0.000
H26.3 Drug-induced cataract
0.422 0.578 0.000
H26.2 Complicated cataract
0.422 0.578 0.000
H26.1 Traumatic cataract
0.422 0.578 0.000
H26.0 Infantile, juvenile and presenile cataract
0.422 0.578 0.000
S29 Other and unspecified injuries of thorax
0.422 0.578 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.422 0.578 0.000
S26 Injury of heart
0.422 0.578 0.000
S25 Injury of blood vessels of thorax
0.422 0.578 0.000
S24 Injury of nerves and spinal cord at thorax level
0.422 0.578 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.422 0.578 0.000
S21 Open wound of thorax
0.422 0.578 0.000
B95-B98 Bacterial, viral and other infectious agents
0.421 0.579 0.000
H16 Keratitis
0.421 0.579 0.000
H18 Other disorders of cornea
0.420 0.580 0.000
B15-B19 Viral hepatitis
0.419 0.581 0.000
S32.0 Fracture of lumbar vertebra
0.418 0.582 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.417 0.583 0.000
F80-F89 Disorders of psychological development
0.417 0.583 0.000
F70-F79 Mental retardation
0.417 0.583 0.000
F60-F69 Disorders of adult personality and behaviour
0.417 0.583 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.417 0.583 0.000
M54 Dorsalgia
0.417 0.583 0.000
A00-A09 Intestinal infectious diseases
0.416 0.584 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.415 0.584 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.415 0.585 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.413 0.587 0.000
A41 Other septicaemia
0.412 0.588 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.412 0.588 0.000
I35.1 Aortic (valve) insufficiency
0.411 0.589 0.000
S06 Intracranial injury
0.409 0.590 0.000
H52 Disorders of refraction and accommodation
0.409 0.591 0.000
I51 Complications and ill-defined descriptions of heart disease
0.407 0.592 0.000
M47.9 Spondylosis, unspecified
0.406 0.594 0.000
E14 Unspecified diabetes mellitus
0.405 0.595 0.000
S42.2 Fracture of upper end of humerus
0.403 0.597 0.000
G93 Other disorders of brain
0.402 0.598 0.000
S22.3 Fracture of rib
0.402 0.598 0.000
I31 Other diseases of pericardium
0.401 0.599 0.000
S27.0 Traumatic pneumothorax
0.401 0.599 0.000
M19.0 Primary arthrosis of other joints
0.401 0.599 0.000
E53 Deficiency of other B group vitamins
0.399 0.601 0.000
M10.9 Gout, unspecified
0.398 0.602 0.000
Chapter XIV Diseases of the genitourinary system
0.397 0.603 0.000
H34 Retinal vascular occlusions
0.397 0.603 0.000
E11.4 With neurological complications
0.396 0.604 0.000
H33 Retinal detachments and breaks
0.396 0.604 0.000
M80 Osteoporosis with pathological fracture
0.396 0.604 0.000
S22.9 Fracture of bony thorax, part unspecified
0.395 0.604 0.000
S22.8 Fracture of other parts of bony thorax
0.395 0.604 0.000
S22.5 Flail chest
0.395 0.604 0.000
S22.2 Fracture of sternum
0.395 0.604 0.000
S22.1 Multiple fractures of thoracic spine
0.395 0.604 0.000
H44 Disorders of globe
0.395 0.605 0.000
G62 Other polyneuropathies
0.395 0.605 0.000
E65-E68 Obesity and other hyperalimentation
0.394 0.606 0.000
H43 Disorders of vitreous body
0.393 0.607 0.000
M07 Psoriatic and enteropathic arthropathies
0.393 0.607 0.000
E40-E46 Malnutrition
0.393 0.607 0.000
M50 Cervical disk disorders
0.392 0.608 0.000
G50 Disorders of trigeminal nerve
0.392 0.608 0.000
H35 Other retinal disorders
0.392 0.608 0.000
S81 Open wound of lower leg
0.392 0.608 0.000
M46 Other inflammatory spondylopathies
0.391 0.609 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.391 0.609 0.000
H31 Other disorders of choroid
0.391 0.609 0.000
H30 Chorioretinal inflammation
0.391 0.609 0.000
S42.1 Fracture of scapula
0.390 0.610 0.000
G95 Other diseases of spinal cord
0.387 0.613 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.386 0.614 0.000
M11 Other crystal arthropathies
0.386 0.614 0.000
M70-M79 Other soft tissue disorders
0.385 0.615 0.000
S02 Fracture of skull and facial bones
0.385 0.615 0.000
S20.2 Contusion of thorax
0.384 0.615 0.000
G58 Other mononeuropathies
0.384 0.616 0.000
G54 Nerve root and plexus disorders
0.384 0.616 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.384 0.616 0.000
G52 Disorders of other cranial nerves
0.384 0.616 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.384 0.616 0.000
F38 Other mood [affective] disorders
0.383 0.617 0.000
F34 Persistent mood [affective] disorders
0.383 0.617 0.000
F30 Manic episode
0.383 0.617 0.000
F39 Unspecified mood [affective] disorder
0.383 0.617 0.000
G91 Hydrocephalus
0.383 0.617 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.383 0.617 0.000
H20 Iridocyclitis
0.383 0.617 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.383 0.617 0.000
H17 Corneal scars and opacities
0.383 0.617 0.000
H15 Disorders of sclera
0.383 0.617 0.000
H51 Other disorders of binocular movement
0.382 0.617 0.000
H49 Paralytic strabismus
0.382 0.617 0.000
B99-B99 Other infectious diseases
0.382 0.617 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.382 0.617 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.382 0.617 0.000
B65-B83 Helminthiases
0.382 0.617 0.000
B50-B64 Protozoal diseases
0.382 0.617 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.382 0.617 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.382 0.617 0.000
A80-A89 Viral infections of the central nervous system
0.382 0.617 0.000
A75-A79 Rickettsioses
0.382 0.617 0.000
A70-A74 Other diseases caused by chlamydiae
0.382 0.617 0.000
A65-A69 Other spirochaetal diseases
0.382 0.617 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.382 0.617 0.000
A20-A28 Certain zoonotic bacterial diseases
0.382 0.617 0.000
A15-A19 Tuberculosis
0.382 0.617 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.382 0.618 0.000
V10-V19 Pedal cyclist injured in transport accident
0.381 0.619 0.000
M15 Polyarthrosis
0.380 0.619 0.000
I34 Nonrheumatic mitral valve disorders
0.380 0.620 0.000
M19.94 Arthrosis, unspecified (Hand)
0.380 0.620 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.380 0.620 0.000
I46 Cardiac arrest
0.379 0.621 0.000
M13.9 Arthritis, unspecified
0.379 0.621 0.000
E13 Other specified diabetes mellitus
0.379 0.621 0.000
E12 Malnutrition-related diabetes mellitus
0.379 0.621 0.000
M14 Arthropathies in other diseases classified elsewhere
0.378 0.621 0.000
M12 Other specific arthropathies
0.378 0.621 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.378 0.621 0.000
M08 Juvenile arthritis
0.378 0.621 0.000
M05 Seropositive rheumatoid arthritis
0.378 0.621 0.000
H50.1 Divergent concomitant strabismus
0.378 0.621 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.378 0.622 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.378 0.622 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.378 0.622 0.000
S37 Injury of urinary and pelvic organs
0.378 0.622 0.000
S36 Injury of intra-abdominal organs
0.378 0.622 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.378 0.622 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.378 0.622 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.378 0.622 0.000
S31 Open wound of abdomen, lower back and pelvis
0.378 0.622 0.000
M49 Spondylopathies in diseases classified elsewhere
0.378 0.622 0.000
M45 Ankylosing spondylitis
0.378 0.622 0.000
G61 Inflammatory polyneuropathy
0.378 0.622 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.377 0.622 0.000
S48 Traumatic amputation of shoulder and upper arm
0.377 0.622 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.377 0.622 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.377 0.622 0.000
S44 Injury of nerves at shoulder and upper arm level
0.377 0.622 0.000
S41 Open wound of shoulder and upper arm
0.377 0.622 0.000
S40 Superficial injury of shoulder and upper arm
0.377 0.622 0.000
S47 Crushing injury of shoulder and upper arm
0.377 0.622 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.377 0.623 0.000
F32.1 Moderate depressive episode
0.377 0.623 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.376 0.624 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.375 0.625 0.000
M19.8 Other specified arthrosis
0.375 0.625 0.000
M19.2 Other secondary arthrosis
0.375 0.625 0.000
M19.1 Posttraumatic arthrosis of other joints
0.375 0.625 0.000
M18 Arthrosis of first carpometacarpal joint
0.374 0.626 0.000
I05-I09 Chronic rheumatic heart diseases
0.374 0.626 0.000
M65-M68 Disorders of synovium and tendon
0.373 0.626 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.373 0.627 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.373 0.627 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.373 0.627 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.373 0.627 0.000
M54.3 Sciatica
0.372 0.628 0.000
G37 Other demyelinating diseases of central nervous system
0.371 0.629 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.370 0.630 0.000
F10.0 Acute intoxication
0.370 0.630 0.000
G40-G47 Episodic and paroxysmal disorders
0.370 0.630 0.000
M19.98 Arthrosis, unspecified (Other)
0.370 0.630 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.370 0.630 0.000
E20-E35 Disorders of other endocrine glands
0.370 0.630 0.000
G59.0 Diabetic mononeuropathy
0.370 0.630 0.000
G25 Other extrapyramidal and movement disorders
0.368 0.632 0.000
G24 Dystonia
0.368 0.632 0.000
G23 Other degenerative diseases of basal ganglia
0.368 0.632 0.000
G21 Secondary Parkinsonism
0.368 0.632 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.368 0.632 0.000
G22 Parkinsonism in diseases classified elsewhere
0.368 0.632 0.000
F32.8 Other depressive episodes
0.367 0.633 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.367 0.633 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.367 0.633 0.000
F32.0 Mild depressive episode
0.367 0.633 0.000
S22.41 Multiple fractures of ribs (open)
0.363 0.637 0.000
S60-S69 Injuries to the wrist and hand
0.363 0.637 0.000
M85 Other disorders of bone density and structure
0.362 0.638 0.000
H50.9 Strabismus, unspecified
0.362 0.638 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.361 0.639 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.360 0.640 0.000
E11.8 With unspecified complications
0.360 0.640 0.000
E11.7 With multiple complications
0.360 0.640 0.000
E11.6 With other specified complications
0.360 0.640 0.000
E11.5 With peripheral circulatory complications
0.360 0.640 0.000
E11.1 With ketoacidosis
0.360 0.640 0.000
E11.0 With coma
0.360 0.640 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.359 0.640 0.000
Q80-Q89 Other congenital malformations
0.359 0.640 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.359 0.640 0.000
Q60-Q64 Congenital malformations of the urinary system
0.359 0.640 0.000
Q50-Q56 Congenital malformations of genital organs
0.359 0.640 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.359 0.640 0.000
Q35-Q37 Cleft lip and cleft palate
0.359 0.640 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.359 0.640 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.359 0.640 0.000
Q00-Q07 Congenital malformations of the nervous system
0.359 0.640 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.359 0.640 0.000
W20-W49 Exposure to inanimate mechanical forces
0.358 0.642 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.358 0.642 0.000
G96 Other disorders of central nervous system
0.358 0.642 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.358 0.642 0.000
G90 Disorders of autonomic nervous system
0.358 0.642 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.358 0.642 0.000
G92 Toxic encephalopathy
0.358 0.642 0.000
M41 Scoliosis
0.357 0.643 0.000
G35 Multiple sclerosis
0.357 0.643 0.000
S32.5 Fracture of pubis
0.357 0.643 0.000
H25 Senile cataract
0.357 0.643 0.000
F31 Bipolar affective disorder
0.356 0.644 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.356 0.644 0.000
G30 Alzheimer's disease
0.355 0.645 0.000
E53.8 Deficiency of other specified B group vitamins
0.354 0.646 0.000
M47.2 Other spondylosis with radiculopathy
0.354 0.646 0.000
I00-I02 Acute rheumatic fever
0.354 0.646 0.000
M47.89 Other spondylosis (Site unspecified)
0.354 0.646 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.353 0.646 0.000
U80 Agent resistant to penicillin and related antibiotics
0.354 0.646 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.353 0.647 0.000
S42.20 Fracture of upper end of humerus (closed)
0.353 0.647 0.000
G51 Facial nerve disorders
0.353 0.647 0.000
G60 Hereditary and idiopathic neuropathy
0.353 0.647 0.000
G64 Other disorders of peripheral nervous system
0.353 0.647 0.000
I31.3 Pericardial effusion (noninflammatory)
0.352 0.648 0.000
S91 Open wound of ankle and foot
0.352 0.648 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.352 0.648 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.351 0.648 0.000
G56.8 Other mononeuropathies of upper limb
0.351 0.648 0.000
G56.4 Causalgia
0.351 0.648 0.000
G56.3 Lesion of radial nerve
0.351 0.648 0.000
G56.1 Other lesions of median nerve
0.351 0.648 0.000
S42.3 Fracture of shaft of humerus
0.351 0.649 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.350 0.650 0.000
I52 Other heart disorders in diseases classified elsewhere
0.350 0.650 0.000
I48 Atrial fibrillation and flutter
0.350 0.650 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.350 0.650 0.000
I41 Myocarditis in diseases classified elsewhere
0.350 0.650 0.000
I40 Acute myocarditis
0.350 0.650 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.350 0.650 0.000
I37 Pulmonary valve disorders
0.350 0.650 0.000
I36 Nonrheumatic tricuspid valve disorders
0.350 0.650 0.000
I33 Acute and subacute endocarditis
0.350 0.650 0.000
I32 Pericarditis in diseases classified elsewhere
0.350 0.650 0.000
I30 Acute pericarditis
0.350 0.650 0.000
F10.3 Withdrawal state
0.350 0.650 0.000
S08 Traumatic amputation of part of head
0.350 0.650 0.000
S07 Crushing injury of head
0.350 0.650 0.000
S05 Injury of eye and orbit
0.350 0.650 0.000
S04 Injury of cranial nerves
0.350 0.650 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.350 0.650 0.000
V20-V29 Motorcycle rider injured in transport accident
0.350 0.650 0.000
M47.86 Other spondylosis (Lumbar region)
0.350 0.650 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.349 0.650 0.000
I51.8 Other ill-defined heart diseases
0.349 0.650 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.349 0.651 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.349 0.651 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.349 0.651 0.000
S00 Superficial injury of head
0.349 0.651 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.349 0.651 0.000
F10.2 Dependence syndrome
0.349 0.651 0.000
I10-I15 Hypertensive diseases
0.348 0.652 0.000
S89 Other and unspecified injuries of lower leg
0.348 0.652 0.000
G12 Spinal muscular atrophy and related syndromes
0.348 0.652 0.000
N20-N23 Urolithiasis
0.348 0.652 0.000
T78 Adverse effects, not elsewhere classified
0.348 0.652 0.000
H54 Blindness and low vision
0.348 0.652 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.347 0.652 0.000
M53 Other dorsopathies, not elsewhere classified
0.347 0.652 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.347 0.653 0.000
H46 Optic neuritis
0.347 0.653 0.000
M47.1 Other spondylosis with myelopathy
0.347 0.653 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.347 0.653 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.346 0.654 0.000
F33 Recurrent depressive disorder
0.346 0.654 0.000
I42.0 Dilated cardiomyopathy
0.346 0.654 0.000
S42.0 Fracture of clavicle
0.345 0.655 0.000
T31 Burns classified according to extent of body surface involved
0.345 0.655 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.345 0.655 0.000
H21.8 Other specified disorders of iris and ciliary body
0.344 0.656 0.000
N00-N08 Glomerular diseases
0.344 0.656 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.344 0.656 0.000
Q28 Other congenital malformations of circulatory system
0.344 0.656 0.000
S27.9 Injury of unspecified intrathoracic organ
0.344 0.656 0.000
S27.8 Injury of other specified intrathoracic organs
0.344 0.656 0.000
S27.7 Multiple injuries of intrathoracic organs
0.344 0.656 0.000
S27.6 Injury of pleura
0.344 0.656 0.000
S27.5 Injury of thoracic trachea
0.344 0.656 0.000
S27.4 Injury of bronchus
0.344 0.656 0.000
S27.3 Other injuries of lung
0.344 0.656 0.000
S27.2 Traumatic heamopneumothorax
0.344 0.656 0.000
S27.1 Traumatic haemothorax
0.344 0.656 0.000
M84 Disorders of continuity of bone
0.343 0.657 0.000
M83 Adult osteomalacia
0.343 0.657 0.000
M82 Osteoporosis in diseases classified elsewhere
0.343 0.657 0.000
F00 Dementia in Alzheimer's disease
0.343 0.657 0.000
M48 Other spondylopathies
0.342 0.658 0.000
G36 Other acute disseminated demyelination
0.341 0.658 0.000
T93 Sequelae of injuries of lower limb
0.341 0.659 0.000
I49 Other cardiac arrhythmias
0.341 0.659 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.341 0.659 0.000
F03 Unspecified dementia
0.341 0.659 0.000
M54.39 Sciatica (Site unspecified)
0.341 0.659 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.340 0.660 0.000
H16.0 Corneal ulcer
0.340 0.660 0.000
S20.7 Multiple superficial injuries of thorax
0.340 0.660 0.000
S20.4 Other superficial injuries of back wall of thorax
0.340 0.660 0.000
S20.3 Other superficial injuries of front wall of thorax
0.340 0.660 0.000
S20.1 Other and unspecified superficial injuries of breast
0.340 0.660 0.000
S20.0 Contusion of breast
0.340 0.660 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.339 0.660 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.339 0.660 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.339 0.660 0.000
S42.4 Fracture of lower end of humerus
0.339 0.660 0.000
M10.99 Gout, unspecified (Site unspecified)
0.339 0.661 0.000
M54.2 Cervicalgia
0.339 0.661 0.000
X60-X84 Intentional self-harm
0.339 0.661 0.000
H50.0 Convergent concomitant strabismus
0.339 0.661 0.000
F01 Vascular dementia
0.338 0.662 0.000
H18.5 Hereditary corneal dystrophies
0.338 0.662 0.000
S88 Traumatic amputation of lower leg
0.338 0.662 0.000
S87 Crushing injury of lower leg
0.338 0.662 0.000
S86 Injury of muscle and tendon at lower leg level
0.338 0.662 0.000
S85 Injury of blood vessels at lower leg level
0.338 0.662 0.000
S84 Injury of nerves at lower leg level
0.338 0.662 0.000
I51.7 Cardiomegaly
0.338 0.662 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.338 0.662 0.000
B18 Chronic viral hepatitis
0.337 0.662 0.000
H11 Other disorders of conjunctiva
0.337 0.662 0.000
G56.2 Lesion of ulnar nerve
0.337 0.663 0.000
D80-D89 Certain disorders involving the immune mechanism
0.337 0.663 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.337 0.663 0.000
S80 Superficial injury of lower leg
0.336 0.664 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.336 0.664 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.336 0.664 0.000
S32.4 Fracture of acetabulum
0.336 0.664 0.000
S32.3 Fracture of ilium
0.336 0.664 0.000
S32.2 Fracture of coccyx
0.336 0.664 0.000
S32.1 Fracture of sacrum
0.336 0.664 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.336 0.664 0.000
Q23 Congenital malformations of aortic and mitral valves
0.335 0.665 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.335 0.665 0.000
M06 Other rheumatoid arthritis
0.334 0.666 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.333 0.666 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.333 0.667 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.333 0.667 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.333 0.667 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.333 0.667 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.333 0.667 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.333 0.667 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.333 0.667 0.000
F11 Mental and behavioural disorders due to use of opioids
0.333 0.667 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.333 0.667 0.000
M50.2 Other cervical disk displacement
0.332 0.668 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.332 0.668 0.000
Y35-Y36 Legal intervention and operations of war
0.332 0.668 0.000
Y10-Y34 Event of undetermined intent
0.332 0.668 0.000
Y00-Y09 Assault
0.332 0.668 0.000
X85-X99 Assault
0.332 0.668 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.332 0.668 0.000
X50-X57 Overexertion, travel and privation
0.332 0.668 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.332 0.668 0.000
X30-X39 Exposure to forces of nature
0.332 0.668 0.000
X20-X29 Contact with venomous animals and plants
0.332 0.668 0.000
X10-X19 Contact with heat and hot substances
0.332 0.668 0.000
X00-X09 Exposure to smoke, fire and flames
0.332 0.668 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.332 0.668 0.000
W75-W84 Other accidental threats to breathing
0.332 0.668 0.000
W65-W74 Accidental drowning and submersion
0.332 0.668 0.000
W50-W64 Exposure to animate mechanical forces
0.332 0.668 0.000
V98-V99 Other and unspecified transport accidents
0.332 0.668 0.000
V95-V97 Air and space transport accidents
0.332 0.668 0.000
V90-V94 Water transport accidents
0.332 0.668 0.000
V80-V89 Other land transport accidents
0.332 0.668 0.000
V70-V79 Bus occupant injured in transport accident
0.332 0.668 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.332 0.668 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.332 0.668 0.000
V40-V49 Car occupant injured in transport accident
0.332 0.668 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.332 0.668 0.000
V01-V09 Pedestrian injured in transport accident
0.332 0.668 0.000
E10.9 Without complications
0.332 0.668 0.000
E10.4 With neurological complications
0.332 0.668 0.000
A41.8 Other specified septicaemia
0.332 0.668 0.000
A48 Other bacterial diseases, not elsewhere classified
0.331 0.669 0.000
A44 Bartonellosis
0.331 0.669 0.000
A43 Nocardiosis
0.331 0.669 0.000
A42 Actinomycosis
0.331 0.669 0.000
A40 Streptococcal septicaemia
0.331 0.669 0.000
A39 Meningococcal infection
0.331 0.669 0.000
A37 Whooping cough
0.331 0.669 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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