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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs141308780
log Bayes Factor = 0.577437
Chromosome 15   position 84,260,542  (GRCh37) Explore rs141308780 on Ensembl!
Variant rs141308780 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.727 0.273 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.724 0.276 0.000
Chapter VI Diseases of the nervous system
0.719 0.281 0.000
Chapter XX External causes of morbidity and mortality
0.710 0.290 0.000
M20-M25 Other joint disorders
0.706 0.294 0.000
Chapter VIII Diseases of the ear and mastoid process
0.703 0.297 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.699 0.301 0.000
G40-G47 Episodic and paroxysmal disorders
0.695 0.305 0.000
M05-M14 Inflammatory polyarthropathies
0.684 0.316 0.000
M23 Internal derangement of knee
0.683 0.317 0.000
M23.3 Other meniscus derangements
0.677 0.323 0.000
G40 Epilepsy
0.664 0.336 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.652 0.348 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.651 0.349 0.000
M35 Other systemic involvement of connective tissue
0.646 0.354 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.642 0.358 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.634 0.366 0.000
H65-H75 Diseases of middle ear and mastoid
0.627 0.373 0.000
M13 Other arthritis
0.626 0.374 0.000
E70-E90 Metabolic disorders
0.625 0.375 0.000
G30-G32 Other degenerative diseases of the nervous system
0.623 0.376 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.619 0.381 0.000
G40.9 Epilepsy, unspecified
0.617 0.383 0.000
W20-W49 Exposure to inanimate mechanical forces
0.613 0.387 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.603 0.397 0.000
T31 Burns classified according to extent of body surface involved
0.601 0.399 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.600 0.400 0.000
M45-M49 Spondylopathies
0.599 0.401 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.598 0.402 0.000
M50-M54 Other dorsopathies
0.596 0.404 0.000
G20-G26 Extrapyramidal and movement disorders
0.594 0.406 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.590 0.410 0.000
H90-H95 Other disorders of ear
0.589 0.411 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.585 0.415 0.000
M13.9 Arthritis, unspecified
0.584 0.416 0.000
M06 Other rheumatoid arthritis
0.583 0.417 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.581 0.419 0.000
H60-H62 Diseases of external ear
0.580 0.420 0.000
M35.3 Polymyalgia rheumatica
0.578 0.422 0.000
S00-S09 Injuries to the head
0.574 0.426 0.000
H80-H83 Diseases of inner ear
0.572 0.428 0.000
T31.0 Burns involving less than 10% of body surface
0.571 0.429 0.000
G90-G99 Other disorders of the nervous system
0.570 0.430 0.000
H65 Nonsuppurative otitis media
0.568 0.432 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.567 0.433 0.000
M86-M90 Other osteopathies
0.566 0.434 0.000
M22 Disorders of patella
0.565 0.435 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.564 0.436 0.000
M40-M43 Deforming dorsopathies
0.563 0.436 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.560 0.440 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.559 0.441 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.552 0.448 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.552 0.448 0.000
S20-S29 Injuries to the thorax
0.551 0.448 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.550 0.450 0.000
M65-M68 Disorders of synovium and tendon
0.548 0.452 0.000
G43 Migraine
0.548 0.452 0.000
S50-S59 Injuries to the elbow and forearm
0.543 0.457 0.000
M00-M03 Infectious arthropathies
0.543 0.457 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.537 0.463 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.537 0.463 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.536 0.464 0.000
X60-X84 Intentional self-harm
0.535 0.464 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.534 0.466 0.000
T79-T79 Certain early complications of trauma
0.534 0.466 0.000
Chapter I Certain infectious and parasitic diseases
0.534 0.466 0.000
M35.0 Sicca syndrome [Sjogren]
0.531 0.469 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.530 0.470 0.000
M80-M85 Disorders of bone density and structure
0.530 0.470 0.000
E20-E35 Disorders of other endocrine glands
0.529 0.471 0.000
M11 Other crystal arthropathies
0.529 0.471 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.528 0.472 0.000
M21 Other acquired deformities of limbs
0.527 0.473 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.527 0.473 0.000
E83 Disorders of mineral metabolism
0.527 0.473 0.000
G30 Alzheimer's disease
0.522 0.477 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.521 0.478 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.521 0.479 0.000
T18 Foreign body in alimentary tract
0.520 0.480 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.520 0.480 0.000
W25 Contact with sharp glass
0.519 0.481 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.519 0.481 0.000
M91-M94 Chondropathies
0.519 0.481 0.000
M60-M63 Disorders of muscles
0.519 0.481 0.000
M31 Other necrotising vasculopathies
0.519 0.481 0.000
T17 Foreign body in respiratory tract
0.518 0.482 0.000
E88 Other metabolic disorders
0.518 0.482 0.000
G70-G73 Diseases of myoneural junction and muscle
0.516 0.484 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.516 0.484 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.513 0.487 0.000
Chapter XXII Codes for special purposes
0.513 0.487 0.000
M06.0 Seronegative rheumatoid arthritis
0.512 0.488 0.000
S60-S69 Injuries to the wrist and hand
0.510 0.490 0.000
M05 Seropositive rheumatoid arthritis
0.509 0.490 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.509 0.491 0.000
Y35-Y36 Legal intervention and operations of war
0.509 0.491 0.000
Y10-Y34 Event of undetermined intent
0.509 0.491 0.000
Y00-Y09 Assault
0.509 0.491 0.000
X85-X99 Assault
0.509 0.491 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.509 0.491 0.000
X50-X57 Overexertion, travel and privation
0.509 0.491 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.509 0.491 0.000
X30-X39 Exposure to forces of nature
0.509 0.491 0.000
X20-X29 Contact with venomous animals and plants
0.509 0.491 0.000
X10-X19 Contact with heat and hot substances
0.509 0.491 0.000
X00-X09 Exposure to smoke, fire and flames
0.509 0.491 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.509 0.491 0.000
W75-W84 Other accidental threats to breathing
0.509 0.491 0.000
W65-W74 Accidental drowning and submersion
0.509 0.491 0.000
W50-W64 Exposure to animate mechanical forces
0.509 0.491 0.000
V98-V99 Other and unspecified transport accidents
0.509 0.491 0.000
V95-V97 Air and space transport accidents
0.509 0.491 0.000
V90-V94 Water transport accidents
0.509 0.491 0.000
V80-V89 Other land transport accidents
0.509 0.491 0.000
V70-V79 Bus occupant injured in transport accident
0.509 0.491 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.509 0.491 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.509 0.491 0.000
V40-V49 Car occupant injured in transport accident
0.509 0.491 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.509 0.491 0.000
V20-V29 Motorcycle rider injured in transport accident
0.509 0.491 0.000
V01-V09 Pedestrian injured in transport accident
0.509 0.491 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.508 0.492 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.507 0.493 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.506 0.494 0.000
M34 Systemic sclerosis
0.506 0.494 0.000
M33 Dermatopolymyositis
0.506 0.494 0.000
M32 Systemic lupus erythematosus
0.506 0.494 0.000
M30 Polyarteritis nodosa and related conditions
0.506 0.494 0.000
M51 Other intervertebral disk disorders
0.504 0.496 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.503 0.496 0.000
Chapter V Mental and behavioural disorders
0.502 0.498 0.000
S70-S79 Injuries to the hip and thigh
0.502 0.498 0.000
M48 Other spondylopathies
0.501 0.499 0.000
T33-T35 Frostbite
0.501 0.499 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.501 0.499 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.501 0.499 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.501 0.499 0.000
T00-T07 Injuries involving multiple body regions
0.501 0.499 0.000
S10-S19 Injuries to the neck
0.501 0.499 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.501 0.499 0.000
M25 Other joint disorders, not elsewhere classified
0.500 0.500 0.000
G44 Other headache syndromes
0.500 0.500 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.498 0.502 0.000
G41 Status epilepticus
0.498 0.502 0.000
H65.3 Chronic mucoid otitis media
0.497 0.503 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.496 0.504 0.000
V10-V19 Pedal cyclist injured in transport accident
0.496 0.504 0.000
Y84.8 Other medical procedures
0.495 0.505 0.000
H92 Otalgia and effusion of ear
0.494 0.506 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.493 0.507 0.000
T66-T78 Other and unspecified effects of external causes
0.493 0.507 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.492 0.508 0.000
M14 Arthropathies in other diseases classified elsewhere
0.491 0.509 0.000
M12 Other specific arthropathies
0.491 0.509 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.491 0.509 0.000
M08 Juvenile arthritis
0.491 0.509 0.000
O60-O75 Complications of labour and delivery
0.491 0.509 0.000
M23.9 Internal derangement of knee, unspecified
0.489 0.510 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.489 0.510 0.000
M23.5 Chronic instability of knee
0.489 0.510 0.000
M23.4 Loose body in knee
0.489 0.510 0.000
M23.1 Discoid meniscus (congenital)
0.489 0.510 0.000
M23.0 Cystic meniscus
0.489 0.510 0.000
S90-S99 Injuries to the ankle and foot
0.488 0.511 0.000
H61 Other disorders of external ear
0.488 0.512 0.000
H73 Other disorders of tympanic membrane
0.487 0.513 0.000
Y86 Sequelae of other accidents
0.487 0.513 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.486 0.514 0.000
M23.37 Other meniscus derangements-Capsular lig
0.486 0.514 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.486 0.514 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.486 0.514 0.000
E10-E14 Diabetes mellitus
0.485 0.515 0.000
M07 Psoriatic and enteropathic arthropathies
0.483 0.517 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.481 0.519 0.000
S00 Superficial injury of head
0.481 0.519 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.479 0.521 0.000
Q60-Q64 Congenital malformations of the urinary system
0.478 0.522 0.000
G40.8 Other epilepsy
0.476 0.524 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.476 0.524 0.000
G40.5 Special epileptic syndromes
0.476 0.524 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.476 0.524 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.476 0.524 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.476 0.524 0.000
Y88 Sequelae of surgical and medical care as external cause
0.475 0.525 0.000
Y40 Systemic antibiotics
0.474 0.525 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.475 0.525 0.000
W44 Foreign body entering into or through eye or natural orifice
0.474 0.526 0.000
G20 Parkinson's disease
0.472 0.528 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.472 0.528 0.000
G82 Paraplegia and tetraplegia
0.471 0.529 0.000
G47 Sleep disorders
0.471 0.529 0.000
Y83.6 Removal of other organ (partial) (total)
0.467 0.533 0.000
E40-E46 Malnutrition
0.467 0.533 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.467 0.533 0.000
G95 Other diseases of spinal cord
0.466 0.534 0.000
Y84.6 Urinary catheterisation
0.465 0.535 0.000
M24 Other specific joint derangements
0.465 0.535 0.000
B35-B49 Mycoses
0.465 0.535 0.000
M54 Dorsalgia
0.465 0.535 0.000
E87.7 Fluid overload
0.465 0.535 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.463 0.537 0.000
M35.8 Other specified systemic involvement of connective tissue
0.463 0.537 0.000
M35.7 Hypermobility syndrome
0.463 0.537 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.463 0.537 0.000
M35.5 Multifocal fibrosclerosis
0.463 0.537 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.463 0.537 0.000
M35.2 Behcet's disease
0.463 0.537 0.000
M35.1 Other overlap syndromes
0.463 0.537 0.000
M65 Synovitis and tenosynovitis
0.462 0.538 0.000
H65.4 Other chronic nonsuppurative otitis media
0.462 0.538 0.000
T32 Corrosions classified according to extent of body surface involved
0.460 0.540 0.000
T30 Burn and corrosion, body region unspecified
0.460 0.540 0.000
T29 Burns and corrosions of multiple body regions
0.460 0.540 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.460 0.540 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.459 0.541 0.000
H83 Other diseases of inner ear
0.456 0.544 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.456 0.544 0.000
M45 Ankylosing spondylitis
0.455 0.545 0.000
W29 Contact with other powered hand tools and household machinery
0.455 0.545 0.000
Q80-Q89 Other congenital malformations
0.454 0.545 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.454 0.546 0.000
S01 Open wound of head
0.452 0.548 0.000
W25.9 Unspecified place
0.452 0.548 0.000
G30.9 Alzheimer's disease, unspecified
0.450 0.550 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.450 0.550 0.000
H74 Other disorders of middle ear and mastoid
0.450 0.550 0.000
H70 Mastoiditis and related conditions
0.450 0.550 0.000
H69 Other disorders of Eustachian tube
0.450 0.550 0.000
H68 Eustachian salpingitis and obstruction
0.450 0.550 0.000
H67 Otitis media in diseases classified elsewhere
0.450 0.550 0.000
H71 Cholesteatoma of middle ear
0.450 0.550 0.000
G25 Other extrapyramidal and movement disorders
0.450 0.550 0.000
T18.1 Foreign body in oesophagus
0.449 0.551 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.449 0.551 0.000
M13.8 Other specified arthritis
0.449 0.551 0.000
M13.1 Monoarthritis, not elsewhere classified
0.449 0.551 0.000
M13.0 Polyarthritis, unspecified
0.449 0.551 0.000
E85 Amyloidosis
0.448 0.552 0.000
E84 Cystic fibrosis
0.448 0.552 0.000
E79 Disorders of purine and pyrimidine metabolism
0.448 0.552 0.000
E77 Disorders of glycoprotein metabolism
0.448 0.552 0.000
E76 Disorders of glycosaminoglycan metabolism
0.448 0.552 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.448 0.552 0.000
E74 Other disorders of carbohydrate metabolism
0.448 0.552 0.000
E73 Lactose intolerance
0.448 0.552 0.000
E72 Other disorders of amino-acid metabolism
0.448 0.552 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.448 0.552 0.000
E70 Disorders of aromatic amino-acid metabolism
0.448 0.552 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.448 0.552 0.000
E83.4 Disorders of magnesium metabolism
0.448 0.552 0.000
G24 Dystonia
0.448 0.552 0.000
M10 Gout
0.448 0.552 0.000
M90 Osteopathies in diseases classified elsewhere
0.447 0.553 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.447 0.553 0.000
T17.2 Foreign body in pharynx
0.446 0.554 0.000
H90 Conductive and sensorineural hearing loss
0.446 0.554 0.000
E87.6 Hypokalaemia
0.445 0.554 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.445 0.555 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.445 0.555 0.000
Y52 Agents primarily affecting the cardiovascular system
0.445 0.555 0.000
G81 Hemiplegia
0.444 0.556 0.000
S09 Other and unspecified injuries of head
0.444 0.556 0.000
T19 Foreign body in genito-urinary tract
0.444 0.556 0.000
T15 Foreign body on external eye
0.444 0.556 0.000
T16 Foreign body in ear
0.444 0.556 0.000
S62 Fracture at wrist and hand level
0.444 0.556 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.443 0.557 0.000
H93 Other disorders of ear, not elsewhere classified
0.443 0.557 0.000
O70 Perineal laceration during delivery
0.443 0.557 0.000
G43.9 Migraine, unspecified
0.442 0.558 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.442 0.558 0.000
M22.4 Chondromalacia patellae
0.441 0.559 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.440 0.559 0.000
H66 Suppurative and unspecified otitis media
0.440 0.560 0.000
Y85 Sequelae of transport accidents
0.440 0.560 0.000
S40-S49 Injuries to the shoulder and upper arm
0.440 0.560 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.440 0.560 0.000
W46 Contact with hypodermic needle
0.440 0.560 0.000
W45 Foreign body or object entering through skin
0.440 0.560 0.000
W43 Exposure to vibration
0.440 0.560 0.000
W42 Exposure to noise
0.440 0.560 0.000
W41 Exposure to high-pressure jet
0.440 0.560 0.000
W40 Explosion of other materials
0.440 0.560 0.000
W39 Discharge of firework
0.440 0.560 0.000
W38 Explosion and rupture of other specified pressurised devices
0.440 0.560 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.440 0.560 0.000
W36 Explosion and rupture of gas cylinder
0.440 0.560 0.000
W35 Explosion and rupture of boiler
0.440 0.560 0.000
W34 Discharge from other and unspecified firearms
0.440 0.560 0.000
W33 Rifle, shotgun and larger firearm discharge
0.440 0.560 0.000
W32 Handgun discharge
0.440 0.560 0.000
W31 Contact with other and unspecified machinery
0.440 0.560 0.000
W30 Contact with agricultural machinery
0.440 0.560 0.000
W28 Contact with powered lawn mower
0.440 0.560 0.000
W27 Contact with nonpowered hand tool
0.440 0.560 0.000
W26 Contact with knife, sword or dagger
0.440 0.560 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.440 0.560 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.440 0.560 0.000
W22 Striking against or struck by other objects
0.440 0.560 0.000
W21 Striking against or struck by sports equipment
0.440 0.560 0.000
W20 Struck by thrown, projected or falling object
0.440 0.560 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.439 0.561 0.000
E86 Volume depletion
0.438 0.562 0.000
O85-O92 Complications predominantly related to the puerperium
0.436 0.564 0.000
M22.8 Other disorders of patella
0.436 0.564 0.000
H72 Perforation of tympanic membrane
0.435 0.564 0.000
R21 Rash and other nonspecific skin eruption
0.435 0.565 0.000
E87.5 Hyperkalaemia
0.435 0.565 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.434 0.566 0.000
H61.0 Perichondritis of external ear
0.433 0.567 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.433 0.567 0.000
E87.2 Acidosis
0.432 0.568 0.000
G35 Multiple sclerosis
0.432 0.568 0.000
E13 Other specified diabetes mellitus
0.432 0.568 0.000
M48.0 Spinal stenosis
0.432 0.568 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.432 0.568 0.000
T31.9 Burns involving 90% or more of body surface
0.431 0.569 0.000
T31.8 Burns involving 80-89% of body surface
0.431 0.569 0.000
T31.7 Burns involving 70-79% of body surface
0.431 0.569 0.000
T31.6 Burns involving 60-69% of body surface
0.431 0.569 0.000
T31.5 Burns involving 50-59% of body surface
0.431 0.569 0.000
T31.4 Burns involving 40-49% of body surface
0.431 0.569 0.000
T31.3 Burns involving 30-39% of body surface
0.431 0.569 0.000
T31.2 Burns involving 20-29% of body surface
0.431 0.569 0.000
T31.1 Burns involving 10-19% of body surface
0.431 0.569 0.000
Y89 Sequelae of other external causes
0.430 0.570 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.430 0.570 0.000
H80 Otosclerosis
0.430 0.570 0.000
M46 Other inflammatory spondylopathies
0.429 0.571 0.000
M49 Spondylopathies in diseases classified elsewhere
0.429 0.571 0.000
Y59 Other and unspecified vaccines and biological substances
0.429 0.571 0.000
Y58 Bacterial vaccines
0.429 0.571 0.000
Y57 Other and unspecified drugs and medicaments
0.429 0.571 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.429 0.571 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.429 0.571 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.429 0.571 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.429 0.571 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.429 0.571 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.429 0.571 0.000
Y48 Anaesthetics and therapeutic gases
0.429 0.571 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.429 0.571 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.429 0.571 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.429 0.571 0.000
M41 Scoliosis
0.429 0.571 0.000
Y44 Agents primarily affecting blood constituents
0.428 0.572 0.000
M53 Other dorsopathies, not elsewhere classified
0.427 0.573 0.000
M43 Other deforming dorsopathies
0.427 0.573 0.000
L40-L45 Papulosquamous disorders
0.427 0.573 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.426 0.573 0.000
G96 Other disorders of central nervous system
0.426 0.574 0.000
G23 Other degenerative diseases of basal ganglia
0.426 0.574 0.000
G21 Secondary Parkinsonism
0.426 0.574 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.426 0.574 0.000
G22 Parkinsonism in diseases classified elsewhere
0.426 0.574 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.425 0.575 0.000
H92.0 Otalgia
0.425 0.575 0.000
S32 Fracture of lumbar spine and pelvis
0.424 0.576 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.424 0.576 0.000
G45.4 Transient global amnesia
0.423 0.576 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.423 0.577 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.423 0.577 0.000
Q50-Q56 Congenital malformations of genital organs
0.423 0.577 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.423 0.577 0.000
Q35-Q37 Cleft lip and cleft palate
0.423 0.577 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.423 0.577 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.423 0.577 0.000
Q00-Q07 Congenital malformations of the nervous system
0.423 0.577 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.423 0.577 0.000
H60 Otitis externa
0.422 0.577 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.422 0.578 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.422 0.578 0.000
W00-W19 Falls
0.421 0.579 0.000
H81 Disorders of vestibular function
0.421 0.579 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.420 0.580 0.000
M87 Osteonecrosis
0.420 0.580 0.000
G83 Other paralytic syndromes
0.419 0.581 0.000
G80 Infantile cerebral palsy
0.419 0.581 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.419 0.581 0.000
M13.98 Arthritis, unspecified (Other)
0.419 0.581 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.419 0.581 0.000
M13.93 Arthritis, unspecified (Forearm)
0.419 0.581 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.419 0.581 0.000
L20-L30 Dermatitis and eczema
0.418 0.581 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.418 0.582 0.000
B95-B98 Bacterial, viral and other infectious agents
0.418 0.582 0.000
S50 Superficial injury of forearm
0.418 0.582 0.000
M06.8 Other specified rheumatoid arthritis
0.418 0.582 0.000
M06.4 Inflammatory polyarthropathy
0.418 0.582 0.000
M06.3 Rheumatoid nodule
0.418 0.582 0.000
M06.2 Rheumatoid bursitis
0.418 0.582 0.000
M06.1 Adult-onset Still's disease
0.418 0.582 0.000
M11.2 Other chondrocalcinosis
0.418 0.582 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.418 0.582 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.417 0.583 0.000
M86 Osteomyelitis
0.417 0.583 0.000
M25.8 Other specified joint disorders
0.417 0.583 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.416 0.583 0.000
E87.4 Mixed disorder of acid-base balance
0.416 0.583 0.000
E87.3 Alkalosis
0.416 0.583 0.000
E87.0 Hyperosmolality and hypernatraemia
0.416 0.583 0.000
M54.3 Sciatica
0.416 0.583 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.416 0.584 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.416 0.584 0.000
M47 Spondylosis
0.414 0.586 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.413 0.586 0.000
M51.2 Other specified intervertebral disk displacement
0.413 0.587 0.000
M00 Pyogenic arthritis
0.412 0.587 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.413 0.587 0.000
S08 Traumatic amputation of part of head
0.412 0.588 0.000
S07 Crushing injury of head
0.412 0.588 0.000
S05 Injury of eye and orbit
0.412 0.588 0.000
S04 Injury of cranial nerves
0.412 0.588 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.412 0.588 0.000
M06.9 Rheumatoid arthritis, unspecified
0.411 0.589 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.411 0.589 0.000
Y43 Primarily systemic agents
0.411 0.589 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.411 0.589 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.410 0.590 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.410 0.590 0.000
M25.7 Osteophyte
0.409 0.591 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.409 0.591 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.409 0.591 0.000
G90 Disorders of autonomic nervous system
0.409 0.591 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.409 0.591 0.000
G92 Toxic encephalopathy
0.409 0.591 0.000
S06 Intracranial injury
0.407 0.593 0.000
H65.2 Chronic serous otitis media
0.407 0.593 0.000
H65.1 Other acute nonsuppurative otitis media
0.407 0.593 0.000
H65.0 Acute serous otitis media
0.407 0.593 0.000
M88 Paget's disease of bone [osteitis deformans]
0.406 0.594 0.000
S52 Fracture of forearm
0.406 0.594 0.000
G12 Spinal muscular atrophy and related syndromes
0.406 0.594 0.000
M13.94 Arthritis, unspecified (Hand)
0.405 0.595 0.000
M22.1 Recurrent subluxation of patella
0.405 0.595 0.000
M22.9 Disorder of patella, unspecified
0.405 0.595 0.000
M22.3 Other derangements of patella
0.405 0.595 0.000
M22.2 Patellofemoral disorders
0.405 0.595 0.000
M22.0 Recurrent dislocation of patella
0.405 0.595 0.000
R27 Other lack of coordination
0.405 0.595 0.000
O70.0 First degree perineal laceration during delivery
0.405 0.595 0.000
Y84.9 Medical procedure, unspecified
0.404 0.596 0.000
Y84.7 Blood-sampling
0.404 0.596 0.000
Y84.5 Insertion of gastric or duodenal sound
0.404 0.596 0.000
Y84.4 Aspiration of fluid
0.404 0.596 0.000
Y84.3 Shock therapy
0.404 0.596 0.000
Y84.1 Kidney dialysis
0.404 0.596 0.000
M42 Spinal osteochondrosis
0.404 0.596 0.000
M40 Kyphosis and lordosis
0.404 0.596 0.000
S62.6 Fracture of other finger
0.404 0.596 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.404 0.596 0.000
G93 Other disorders of brain
0.404 0.596 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.402 0.598 0.000
G45.3 Amaurosis fugax
0.402 0.598 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.402 0.598 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.402 0.598 0.000
G45.0 Vertebro-basilar artery syndrome
0.402 0.598 0.000
B37 Candidiasis
0.402 0.598 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.401 0.599 0.000
S37 Injury of urinary and pelvic organs
0.401 0.599 0.000
S36 Injury of intra-abdominal organs
0.401 0.599 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.401 0.599 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.401 0.599 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.401 0.599 0.000
S31 Open wound of abdomen, lower back and pelvis
0.401 0.599 0.000
F60-F69 Disorders of adult personality and behaviour
0.401 0.599 0.000
R25 Abnormal involuntary movements
0.400 0.599 0.000
E00-E07 Disorders of thyroid gland
0.400 0.600 0.000
Y95 Nosocomial condition
0.400 0.600 0.000
M51.8 Other specified intervertebral disk disorders
0.400 0.600 0.000
M21.3 Wrist or foot drop (acquired)
0.400 0.600 0.000
M85 Other disorders of bone density and structure
0.399 0.600 0.000
E78.0 Pure hypercholesterolaemia
0.399 0.601 0.000
Y84.2 Radiological procedure and radiotherapy
0.398 0.602 0.000
Q61 Cystic kidney disease
0.398 0.602 0.000
O00-O08 Pregnancy with abortive outcome
0.397 0.602 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.397 0.603 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.397 0.603 0.000
H91 Other hearing loss
0.397 0.603 0.000
E83.5 Disorders of calcium metabolism
0.397 0.603 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.396 0.603 0.000
E22 Hyperfunction of pituitary gland
0.396 0.604 0.000
S27 Injury of other and unspecified intrathoracic organs
0.396 0.604 0.000
S80-S89 Injuries to the knee and lower leg
0.395 0.604 0.000
G37 Other demyelinating diseases of central nervous system
0.396 0.604 0.000
G36 Other acute disseminated demyelination
0.396 0.604 0.000
S29 Other and unspecified injuries of thorax
0.395 0.604 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.395 0.604 0.000
S26 Injury of heart
0.395 0.604 0.000
S25 Injury of blood vessels of thorax
0.395 0.604 0.000
S24 Injury of nerves and spinal cord at thorax level
0.395 0.604 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.395 0.604 0.000
S21 Open wound of thorax
0.395 0.604 0.000
S20 Superficial injury of thorax
0.395 0.604 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.395 0.605 0.000
E13.9 Without complications
0.394 0.606 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.393 0.607 0.000
M66 Spontaneous rupture of synovium and tendon
0.393 0.607 0.000
G43.8 Other migraine
0.393 0.607 0.000
G43.3 Complicated migraine
0.393 0.607 0.000
G43.2 Status migrainosus
0.393 0.607 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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