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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs141527659
log Bayes Factor = 22.6507
Chromosome 8   position 130,875,935  (GRCh37) Explore rs141527659 on Ensembl!
Variant rs141527659 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
Z95.1 Presence of aortocoronary bypass graft
0.971 0.029 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.970 0.030 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.968 0.032 0.000
I35 Nonrheumatic aortic valve disorders
0.966 0.034 0.000
I50 Heart failure
0.961 0.039 0.000
I47 Paroxysmal tachycardia
0.957 0.043 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.955 0.045 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.954 0.046 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.953 0.047 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.952 0.048 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.948 0.052 0.000
M20 Acquired deformities of fingers and toes
0.947 0.053 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.945 0.055 0.000
M45-M49 Spondylopathies
0.941 0.059 0.000
Z45 Adjustment and management of implanted device
0.937 0.063 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.934 0.066 0.000
K55-K64 Other diseases of intestines
0.931 0.069 0.000
M80-M85 Disorders of bone density and structure
0.930 0.070 0.000
M35 Other systemic involvement of connective tissue
0.926 0.074 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.925 0.075 0.000
I25.1 Atherosclerotic heart disease
0.924 0.076 0.000
I34 Nonrheumatic mitral valve disorders
0.924 0.076 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.917 0.083 0.000
I24 Other acute ischaemic heart diseases
0.915 0.085 0.000
R50-R69 General symptoms and signs
0.915 0.085 0.000
K70-K77 Diseases of liver
0.914 0.086 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.910 0.090 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.910 0.090 0.000
I60-I69 Cerebrovascular diseases
0.909 0.091 0.000
Z95.2 Presence of prosthetic heart valve
0.906 0.094 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.904 0.096 0.000
Z50 Care involving use of rehabilitation procedures
0.904 0.096 0.000
Z45.2 Adjustment and management of vascular access device
0.903 0.097 0.000
S60-S69 Injuries to the wrist and hand
0.902 0.098 0.000
I50.0 Congestive heart failure
0.900 0.100 0.000
I47.1 Supraventricular tachycardia
0.898 0.102 0.000
Z95.0 Presence of cardiac pacemaker
0.898 0.102 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.894 0.106 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.891 0.109 0.000
M35.3 Polymyalgia rheumatica
0.889 0.111 0.000
R50 Fever of unknown origin
0.889 0.111 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.889 0.111 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.888 0.112 0.000
I35.0 Aortic (valve) stenosis
0.886 0.114 0.000
R56 Convulsions, not elsewhere classified
0.885 0.115 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.881 0.119 0.000
Z95.4 Presence of other heart-valve replacement
0.878 0.122 0.000
I22 Subsequent myocardial infarction
0.878 0.122 0.000
Z94 Transplanted organ and tissue status
0.875 0.125 0.000
M47 Spondylosis
0.872 0.128 0.000
M15-M19 Arthrosis
0.872 0.128 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.872 0.128 0.000
I71 Aortic aneurysm and dissection
0.866 0.134 0.000
R56.8 Other and unspecified convulsions
0.863 0.137 0.000
Z85 Personal history of malignant neoplasm
0.861 0.139 0.000
I51 Complications and ill-defined descriptions of heart disease
0.861 0.139 0.000
I67 Other cerebrovascular diseases
0.858 0.142 0.000
M23 Internal derangement of knee
0.858 0.142 0.000
F10.0 Acute intoxication
0.858 0.142 0.000
O60-O75 Complications of labour and delivery
0.856 0.144 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.855 0.145 0.000
Y95 Nosocomial condition
0.854 0.146 0.000
I45 Other conduction disorders
0.851 0.149 0.000
R55 Syncope and collapse
0.850 0.150 0.000
I73 Other peripheral vascular diseases
0.849 0.151 0.000
Z97 Presence of other devices
0.847 0.152 0.000
M16 Coxarthrosis [arthrosis of hip]
0.847 0.153 0.000
I10-I15 Hypertensive diseases
0.847 0.153 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.844 0.156 0.000
T39.1 4-Aminophenol derivatives
0.844 0.156 0.000
R52 Pain, not elsewhere classified
0.843 0.157 0.000
F10.3 Withdrawal state
0.841 0.159 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.840 0.160 0.000
M20.1 Hallux valgus (acquired)
0.839 0.161 0.000
M81 Osteoporosis without pathological fracture
0.838 0.162 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.836 0.164 0.000
R50.9 Fever, unspecified
0.834 0.166 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.834 0.166 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.831 0.169 0.000
K50-K52 Noninfective enteritis and colitis
0.830 0.170 0.000
I50.1 Left ventricular failure
0.828 0.172 0.000
I05-I09 Chronic rheumatic heart diseases
0.828 0.172 0.000
T81 Complications of procedures, not elsewhere classified
0.828 0.172 0.000
K60 Fissure and fistula of anal and rectal regions
0.824 0.176 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.824 0.176 0.000
Chapter VI Diseases of the nervous system
0.823 0.177 0.000
M16.9 Coxarthrosis, unspecified
0.821 0.179 0.000
S62 Fracture at wrist and hand level
0.821 0.179 0.000
Z48 Other surgical follow-up care
0.820 0.180 0.000
K59 Other functional intestinal disorders
0.819 0.181 0.000
Chapter VII Diseases of the eye and adnexa
0.817 0.183 0.000
I47.2 Ventricular tachycardia
0.817 0.183 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.816 0.184 0.000
A80-A89 Viral infections of the central nervous system
0.813 0.187 0.000
I34.1 Mitral (valve) prolapse
0.813 0.187 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.810 0.190 0.000
M20.4 Other hammer toe(s) (acquired)
0.810 0.190 0.000
F30-F39 Mood [affective] disorders
0.807 0.193 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.807 0.193 0.000
A30-A49 Other bacterial diseases
0.807 0.193 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.806 0.194 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.802 0.198 0.000
I77 Other disorders of arteries and arterioles
0.800 0.200 0.000
K35-K38 Diseases of appendix
0.799 0.200 0.000
S00 Superficial injury of head
0.799 0.201 0.000
I34.0 Mitral (valve) insufficiency
0.794 0.206 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.793 0.207 0.000
M20.5 Other deformities of toe(s) (acquired)
0.793 0.207 0.000
I25.3 Aneurysm of heart
0.793 0.207 0.000
M50-M54 Other dorsopathies
0.792 0.208 0.000
K80 Cholelithiasis
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.792 0.208 0.000
I67.9 Cerebrovascular disease, unspecified
0.792 0.208 0.000
S20-S29 Injuries to the thorax
0.790 0.210 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.790 0.210 0.000
I73.9 Peripheral vascular disease, unspecified
0.789 0.211 0.000
Chapter II Neoplasms
0.788 0.212 0.000
M47.8 Other spondylosis
0.787 0.213 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.787 0.213 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.787 0.213 0.000
M70-M79 Other soft tissue disorders
0.787 0.213 0.000
Z51 Other medical care
0.785 0.215 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.785 0.215 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
I20 Angina pectoris
0.784 0.216 0.000
R50.0 Fever with chills
0.784 0.216 0.000
K76 Other diseases of liver
0.782 0.218 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.781 0.219 0.000
I31 Other diseases of pericardium
0.780 0.220 0.000
M31 Other necrotising vasculopathies
0.778 0.221 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.778 0.222 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.776 0.224 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.775 0.225 0.000
M48 Other spondylopathies
0.775 0.225 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.774 0.226 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.773 0.227 0.000
Z93 Artificial opening status
0.773 0.227 0.000
M81.9 Osteoporosis, unspecified
0.772 0.228 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.772 0.228 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.771 0.229 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.771 0.229 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.770 0.230 0.000
I21 Acute myocardial infarction
0.770 0.230 0.000
W20-W49 Exposure to inanimate mechanical forces
0.770 0.230 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.768 0.232 0.000
K74 Fibrosis and cirrhosis of liver
0.768 0.232 0.000
I33 Acute and subacute endocarditis
0.767 0.233 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.767 0.233 0.000
S10-S19 Injuries to the neck
0.766 0.234 0.000
M34 Systemic sclerosis
0.766 0.234 0.000
K60.3 Anal fistula
0.766 0.234 0.000
Z50.1 Other physical therapy
0.763 0.237 0.000
W00-W19 Falls
0.762 0.238 0.000
S00.8 Superficial injury of other parts of head
0.762 0.238 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.762 0.238 0.000
F80-F89 Disorders of psychological development
0.761 0.239 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.761 0.239 0.000
Z51.1 Chemotherapy session for neoplasm
0.761 0.239 0.000
F10.2 Dependence syndrome
0.760 0.240 0.000
H53-H54 Visual disturbances and blindness
0.760 0.240 0.000
K81 Cholecystitis
0.758 0.242 0.000
I35.1 Aortic (valve) insufficiency
0.758 0.242 0.000
Z45.1 Adjustment and management of infusion pump
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.756 0.244 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.756 0.244 0.000
K59.0 Constipation
0.755 0.245 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.755 0.245 0.000
I51.9 Heart disease, unspecified
0.754 0.246 0.000
I24.8 Other forms of acute ischaemic heart disease
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.753 0.247 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.753 0.247 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.752 0.247 0.000
Z50.2 Alcohol rehabilitation
0.752 0.248 0.000
Z95.3 Presence of xenogenic heart valve
0.751 0.249 0.000
M85 Other disorders of bone density and structure
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.750 0.250 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.748 0.252 0.000
Z94.4 Liver transplant status
0.745 0.255 0.000
R52.9 Pain, unspecified
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.743 0.256 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.743 0.257 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.743 0.257 0.000
F10.4 Withdrawal state with delirium
0.742 0.257 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.742 0.258 0.000
A00-A09 Intestinal infectious diseases
0.742 0.258 0.000
M16.0 Primary coxarthrosis, bilateral
0.741 0.259 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.739 0.261 0.000
M91-M94 Chondropathies
0.739 0.261 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.737 0.263 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.737 0.263 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.736 0.264 0.000
I74 Arterial embolism and thrombosis
0.735 0.265 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
M24 Other specific joint derangements
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.732 0.268 0.000
I70 Atherosclerosis
0.732 0.268 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.732 0.268 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.732 0.268 0.000
M22 Disorders of patella
0.731 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.729 0.271 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.729 0.271 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.728 0.272 0.000
T88.4 Failed or difficult intubation
0.728 0.272 0.000
M25 Other joint disorders, not elsewhere classified
0.728 0.272 0.000
O36 Maternal care for other known or suspected foetal problems
0.727 0.273 0.000
Y83.8 Other surgical procedures
0.726 0.274 0.000
M23.4 Loose body in knee
0.725 0.275 0.000
K11 Diseases of salivary glands
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
Z43 Attention to artificial openings
0.724 0.276 0.000
I67.2 Cerebral atherosclerosis
0.723 0.277 0.000
K62 Other diseases of anus and rectum
0.722 0.278 0.000
I42 Cardiomyopathy
0.722 0.278 0.000
Z74 Problems related to care-provider dependency
0.722 0.278 0.000
F10.1 Harmful use
0.722 0.278 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.721 0.279 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.279 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.720 0.279 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.719 0.281 0.000
S32 Fracture of lumbar spine and pelvis
0.719 0.281 0.000
M80 Osteoporosis with pathological fracture
0.719 0.281 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.718 0.281 0.000
M47.86 Other spondylosis (Lumbar region)
0.718 0.282 0.000
Z50.5 Speech therapy
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T82.1 Mechanical complication of cardiac electronic device
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K90-K93 Other diseases of the digestive system
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
K25 Gastric ulcer
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.716 0.284 0.000
I12 Hypertensive renal disease
0.716 0.284 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.716 0.284 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.715 0.285 0.000
Z89 Acquired absence of limb
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.714 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
M21 Other acquired deformities of limbs
0.714 0.286 0.000
Z73 Problems related to life-management difficulty
0.713 0.286 0.000
Z49 Care involving dialysis
0.713 0.287 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
H53 Visual disturbances
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
K22 Other diseases of oesophagus
0.708 0.292 0.000
S70-S79 Injuries to the hip and thigh
0.708 0.292 0.000
S62.6 Fracture of other finger
0.708 0.292 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.705 0.295 0.000
K75 Other inflammatory liver diseases
0.705 0.295 0.000
Z48.0 Attention to surgical dressings and sutures
0.705 0.295 0.000
I08 Multiple valve diseases
0.705 0.295 0.000
K55 Vascular disorders of intestine
0.705 0.295 0.000
I50.9 Heart failure, unspecified
0.704 0.296 0.000
E70-E90 Metabolic disorders
0.702 0.298 0.000
F99-F99 Unspecified mental disorder
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
F60-F69 Disorders of adult personality and behaviour
0.702 0.298 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
S40-S49 Injuries to the shoulder and upper arm
0.701 0.299 0.000
I45.1 Other and unspecified right bundle-branch block
0.700 0.300 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.700 0.300 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.699 0.301 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.699 0.301 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.699 0.301 0.000
Z94.0 Kidney transplant status
0.699 0.301 0.000
G40-G47 Episodic and paroxysmal disorders
0.698 0.301 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.698 0.302 0.000
Z50.8 Care involving use of rehabilitation procedures
0.698 0.302 0.000
I78 Diseases of capillaries
0.697 0.303 0.000
Z97.8 Presence of other specified devices
0.697 0.303 0.000
R59 Enlarged lymph nodes
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.696 0.304 0.000
I72 Other aneurysm
0.696 0.304 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.695 0.304 0.000
M47.2 Other spondylosis with radiculopathy
0.695 0.305 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
K61 Abscess of anal and rectal regions
0.694 0.306 0.000
Z54 Convalescence
0.694 0.306 0.000
Z52 Donors of organs and tissues
0.694 0.306 0.000
Z44 Fitting and adjustment of external prosthetic device
0.694 0.306 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.694 0.306 0.000
Z45.8 Adjustment and management of other implanted devices
0.692 0.308 0.000
I35.9 Aortic valve disorder, unspecified
0.692 0.308 0.000
I35.8 Other aortic valve disorders
0.692 0.308 0.000
Z75 Problems related to medical facilities and other health care
0.690 0.309 0.000
S80-S89 Injuries to the knee and lower leg
0.690 0.310 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.688 0.312 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.688 0.312 0.000
S62.3 Fracture of other metacarpal bone
0.687 0.312 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.686 0.314 0.000
I47.0 Reentry ventricular arrhythmia
0.686 0.314 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.686 0.314 0.000
I49 Other cardiac arrhythmias
0.685 0.315 0.000
I69 Sequelae of cerebrovascular disease
0.685 0.315 0.000
R50.8 Other specified fever
0.685 0.315 0.000
I61 Intracerebral haemorrhage
0.685 0.315 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.685 0.315 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.684 0.316 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.684 0.316 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.684 0.316 0.000
T82.3 Mechanical complication of other vascular grafts
0.684 0.316 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.684 0.316 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.684 0.316 0.000
A87 Viral meningitis
0.684 0.316 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.683 0.316 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.683 0.316 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.683 0.316 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.683 0.316 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.683 0.316 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.683 0.316 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.683 0.316 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.683 0.316 0.000
T36 Poisoning by systemic antibiotics
0.683 0.316 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.682 0.318 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.682 0.318 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.682 0.318 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.682 0.318 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.682 0.318 0.000
Z96 Presence of other functional implants
0.682 0.318 0.000
H10-H13 Disorders of conjunctiva
0.682 0.318 0.000
K51 Ulcerative colitis
0.682 0.318 0.000
K56.7 Ileus, unspecified
0.681 0.319 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.680 0.320 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.680 0.320 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.680 0.320 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.680 0.320 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.680 0.320 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.680 0.320 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.680 0.320 0.000
F11 Mental and behavioural disorders due to use of opioids
0.680 0.320 0.000
M20.3 Other deformity of hallux (acquired)
0.679 0.321 0.000
M20.0 Deformity of finger(s)
0.679 0.321 0.000
K85 Acute pancreatitis
0.678 0.322 0.000
I21.4 Acute subendocardial myocardial infarction
0.678 0.322 0.000
M20.2 Hallux rigidus
0.677 0.322 0.000
R63 Symptoms and signs concerning food and fluid intake
0.677 0.323 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.677 0.323 0.000
K31 Other diseases of stomach and duodenum
0.677 0.323 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.677 0.323 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.677 0.323 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.677 0.323 0.000
K62.0 Anal polyp
0.677 0.323 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.677 0.323 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.676 0.324 0.000
R52.1 Chronic intractable pain
0.676 0.324 0.000
I63 Cerebral infarction
0.676 0.324 0.000
M47.9 Spondylosis, unspecified
0.675 0.324 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.326 0.000
M46 Other inflammatory spondylopathies
0.674 0.326 0.000
M45 Ankylosing spondylitis
0.674 0.326 0.000
S09 Other and unspecified injuries of head
0.674 0.326 0.000
S02 Fracture of skull and facial bones
0.673 0.327 0.000
Z90.0 Acquired absence of part of head and neck
0.672 0.328 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.671 0.328 0.000
Z45.3 Adjustment and management of implanted hearing device
0.671 0.328 0.000
Y84.8 Other medical procedures
0.671 0.329 0.000
R81 Glycosuria
0.671 0.329 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.670 0.330 0.000
I31.3 Pericardial effusion (noninflammatory)
0.670 0.330 0.000
A41 Other septicaemia
0.670 0.330 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
F10.9 Unspecified mental and behavioural disorder
0.670 0.330 0.000
F10.8 Other mental and behavioural disorders
0.670 0.330 0.000
F10.7 Residual and late-onset psychotic disorder
0.670 0.330 0.000
F10.6 Amnesic syndrome
0.670 0.330 0.000
F10.5 Psychotic disorder
0.670 0.330 0.000
K01 Embedded and impacted teeth
0.669 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.669 0.331 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.669 0.331 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.668 0.332 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.668 0.332 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.668 0.332 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.668 0.332 0.000
K72 Hepatic failure, not elsewhere classified
0.668 0.332 0.000
K20 Oesophagitis
0.668 0.332 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.667 0.332 0.000
Z51.5 Palliative care
0.667 0.333 0.000
R52.2 Other chronic pain
0.667 0.333 0.000
M84 Disorders of continuity of bone
0.666 0.333 0.000
M83 Adult osteomalacia
0.666 0.333 0.000
M82 Osteoporosis in diseases classified elsewhere
0.666 0.333 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.666 0.334 0.000
K12 Stomatitis and related lesions
0.666 0.334 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.665 0.335 0.000
F32 Depressive episode
0.665 0.335 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.664 0.336 0.000
M35.8 Other specified systemic involvement of connective tissue
0.664 0.336 0.000
M35.7 Hypermobility syndrome
0.664 0.336 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.664 0.336 0.000
M35.5 Multifocal fibrosclerosis
0.664 0.336 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.664 0.336 0.000
M35.2 Behcet's disease
0.664 0.336 0.000
M35.1 Other overlap syndromes
0.664 0.336 0.000
R04 Haemorrhage from respiratory passages
0.664 0.336 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.663 0.337 0.000
O85-O92 Complications predominantly related to the puerperium
0.663 0.337 0.000
Chapter VIII Diseases of the ear and mastoid process
0.663 0.337 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.662 0.338 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.662 0.338 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.662 0.338 0.000
Z85.6 Personal history of leukaemia
0.662 0.338 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.338 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.660 0.340 0.000
Z86 Personal history of certain other diseases
0.658 0.342 0.000
S68 Traumatic amputation of wrist and hand
0.657 0.343 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.657 0.343 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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