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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs141853578
log Bayes Factor = 7.78323
Chromosome 4   position 110,685,820  (GRCh37) Explore rs141853578 on Ensembl!
Variant rs141853578 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.990 0.010 0.000
I25 Chronic ischaemic heart disease
0.981 0.019 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.976 0.024 0.000
R50-R69 General symptoms and signs
0.950 0.050 0.000
Chapter XIV Diseases of the genitourinary system
0.950 0.050 0.000
Z86 Personal history of certain other diseases
0.927 0.073 0.000
Chapter VII Diseases of the eye and adnexa
0.926 0.074 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.924 0.076 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.923 0.077 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.908 0.092 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.904 0.096 0.000
I25.1 Atherosclerotic heart disease
0.903 0.097 0.000
Chapter V Mental and behavioural disorders
0.903 0.097 0.000
I30-I52 Other forms of heart disease
0.902 0.098 0.000
R07 Pain in throat and chest
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.900 0.100 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.899 0.101 0.000
N30-N39 Other diseases of urinary system
0.882 0.118 0.000
Z92 Personal history of medical treatment
0.879 0.121 0.000
Chapter X Diseases of the respiratory system
0.878 0.122 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.870 0.130 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.866 0.134 0.000
H30-H36 Disorders of choroid and retina
0.862 0.138 0.000
I22 Subsequent myocardial infarction
0.852 0.148 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.838 0.162 0.000
I25.2 Old myocardial infarction
0.836 0.164 0.000
Chapter II Neoplasms
0.834 0.166 0.000
Chapter XI Diseases of the digestive system
0.831 0.169 0.000
R69 Unknown and unspecified causes of morbidity
0.829 0.171 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.828 0.172 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.825 0.175 0.000
R07.4 Chest pain, unspecified
0.819 0.181 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.815 0.185 0.000
R05 Cough
0.814 0.186 0.000
Chapter XX External causes of morbidity and mortality
0.814 0.186 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.814 0.186 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.813 0.187 0.000
Z86.7 Personal history of diseases of the circulatory system
0.806 0.194 0.000
I47 Paroxysmal tachycardia
0.800 0.200 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.798 0.202 0.000
R04 Haemorrhage from respiratory passages
0.797 0.203 0.000
Z86.4 Personal history of psychoactive substance abuse
0.796 0.204 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.794 0.206 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.792 0.208 0.000
R50 Fever of unknown origin
0.789 0.211 0.000
Z85 Personal history of malignant neoplasm
0.788 0.212 0.000
K55-K64 Other diseases of intestines
0.783 0.217 0.000
H35 Other retinal disorders
0.783 0.217 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.780 0.220 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.780 0.220 0.000
N39 Other disorders of urinary system
0.780 0.220 0.000
Z86.0 Personal history of other neoplasms
0.774 0.226 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.771 0.229 0.000
Z96 Presence of other functional implants
0.769 0.231 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.764 0.236 0.000
I21 Acute myocardial infarction
0.763 0.237 0.000
N17-N19 Renal failure
0.763 0.237 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.757 0.243 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.755 0.245 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.753 0.246 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.753 0.247 0.000
E70-E90 Metabolic disorders
0.753 0.247 0.000
R19.4 Change in bowel habit
0.753 0.247 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.751 0.249 0.000
R63 Symptoms and signs concerning food and fluid intake
0.751 0.249 0.000
E00-E07 Disorders of thyroid gland
0.750 0.250 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.749 0.251 0.000
R53 Malaise and fatigue
0.749 0.251 0.000
R18 Ascites
0.749 0.251 0.000
F30-F39 Mood [affective] disorders
0.747 0.253 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.746 0.254 0.000
R55 Syncope and collapse
0.743 0.256 0.000
Chapter VI Diseases of the nervous system
0.743 0.257 0.000
N20-N23 Urolithiasis
0.740 0.260 0.000
N40-N51 Diseases of male genital organs
0.739 0.261 0.000
Z98 Other postsurgical states
0.738 0.262 0.000
J40-J47 Chronic lower respiratory diseases
0.737 0.263 0.000
I50 Heart failure
0.733 0.267 0.000
N32 Other disorders of bladder
0.732 0.268 0.000
M05-M14 Inflammatory polyarthropathies
0.730 0.270 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.729 0.271 0.000
R12 Heartburn
0.727 0.273 0.000
M20-M25 Other joint disorders
0.727 0.273 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.727 0.273 0.000
K62 Other diseases of anus and rectum
0.726 0.274 0.000
R07.3 Other chest pain
0.725 0.275 0.000
Chapter VIII Diseases of the ear and mastoid process
0.722 0.278 0.000
Chapter I Certain infectious and parasitic diseases
0.721 0.279 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
R47-R49 Symptoms and signs involving speech and voice
0.717 0.283 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.717 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.716 0.283 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.716 0.284 0.000
R00 Abnormalities of heart beat
0.714 0.286 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.714 0.286 0.000
I60-I69 Cerebrovascular diseases
0.714 0.286 0.000
I05-I09 Chronic rheumatic heart diseases
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.713 0.287 0.000
Z97 Presence of other devices
0.713 0.287 0.000
Z94 Transplanted organ and tissue status
0.713 0.287 0.000
Z93 Artificial opening status
0.713 0.287 0.000
Z89 Acquired absence of limb
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z83 Family history of other specific disorders
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
H25-H28 Disorders of lens
0.711 0.288 0.000
M15-M19 Arthrosis
0.711 0.289 0.000
Z13 Special screening examination for other diseases and disorders
0.710 0.290 0.000
I24 Other acute ischaemic heart diseases
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
Z87 Personal history of other diseases and conditions
0.709 0.291 0.000
Z53.8 Procedure not carried out for other reasons
0.706 0.294 0.000
N39.0 Urinary tract infection, site not specified
0.706 0.294 0.000
R79 Other abnormal findings of blood chemistry
0.705 0.295 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.703 0.296 0.000
I25.6 Silent myocardial ischaemia
0.703 0.297 0.000
I25.5 Ischaemic cardiomyopathy
0.703 0.297 0.000
I25.4 Coronary artery aneurysm
0.703 0.297 0.000
I25.3 Aneurysm of heart
0.703 0.297 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.703 0.297 0.000
R42 Dizziness and giddiness
0.702 0.298 0.000
Z02 Examination and encounter for administrative purposes
0.701 0.299 0.000
I20 Angina pectoris
0.700 0.300 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.700 0.300 0.000
R01 Cardiac murmurs and other cardiac sounds
0.700 0.300 0.000
R02 Gangrene, not elsewhere classified
0.700 0.300 0.000
E10-E14 Diabetes mellitus
0.699 0.301 0.000
D10-D36 Benign neoplasms
0.698 0.301 0.000
M45-M49 Spondylopathies
0.698 0.302 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.697 0.303 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.695 0.305 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.693 0.307 0.000
K62.5 Haemorrhage of anus and rectum
0.686 0.314 0.000
I47.1 Supraventricular tachycardia
0.684 0.316 0.000
N35 Urethral stricture
0.684 0.316 0.000
Z92.3 Personal history of irradiation
0.682 0.318 0.000
R68 Other general symptoms and signs
0.681 0.319 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.681 0.319 0.000
R62 Lack of expected normal physiological development
0.681 0.319 0.000
R61 Hyperhidrosis
0.681 0.319 0.000
R60 Oedema, not elsewhere classified
0.681 0.319 0.000
R59 Enlarged lymph nodes
0.681 0.319 0.000
R57 Shock, not elsewhere classified
0.681 0.319 0.000
R56 Convulsions, not elsewhere classified
0.681 0.319 0.000
R52 Pain, not elsewhere classified
0.681 0.319 0.000
R64 Cachexia
0.681 0.319 0.000
R58 Haemorrhage, not elsewhere classified
0.681 0.319 0.000
R54 Senility
0.681 0.319 0.000
N99-N99 Other disorders of the genitourinary system
0.681 0.319 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.681 0.319 0.000
N60-N64 Disorders of breast
0.681 0.319 0.000
N25-N29 Other disorders of kidney and ureter
0.681 0.319 0.000
N10-N16 Renal tubulo-interstitial diseases
0.681 0.319 0.000
N00-N08 Glomerular diseases
0.681 0.319 0.000
J95-J99 Other diseases of the respiratory system
0.681 0.319 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.681 0.319 0.000
H33 Retinal detachments and breaks
0.681 0.319 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.679 0.321 0.000
H35.3 Degeneration of macula and posterior pole
0.679 0.321 0.000
Z53.0 Procedure not carried out because of contraindication
0.679 0.321 0.000
R06 Abnormalities of breathing
0.675 0.324 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.674 0.326 0.000
R50.9 Fever, unspecified
0.674 0.326 0.000
Z80 Family history of malignant neoplasm
0.673 0.327 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.670 0.329 0.000
H36 Retinal disorders in diseases classified elsewhere
0.669 0.330 0.000
M50-M54 Other dorsopathies
0.668 0.332 0.000
J09-J18 Influenza and pneumonia
0.666 0.334 0.000
R07.2 Precordial pain
0.666 0.334 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.666 0.334 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.665 0.335 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.665 0.335 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.665 0.335 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.665 0.335 0.000
H55-H59 Other disorders of eye and adnexa
0.664 0.336 0.000
H53-H54 Visual disturbances and blindness
0.664 0.336 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.664 0.336 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.664 0.336 0.000
H43-H45 Disorders of vitreous body and globe
0.664 0.336 0.000
H40-H42 Glaucoma
0.664 0.336 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.664 0.336 0.000
H10-H13 Disorders of conjunctiva
0.664 0.336 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.664 0.336 0.000
H35.8 Other specified retinal disorders
0.663 0.337 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.662 0.338 0.000
Z10 Routine general health check-up of defined subpopulation
0.662 0.338 0.000
Z04 Examination and observation for other reasons
0.662 0.338 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.662 0.338 0.000
R30-R39 Symptoms and signs involving the urinary system
0.658 0.341 0.000
I47.2 Ventricular tachycardia
0.658 0.342 0.000
J20-J22 Other acute lower respiratory infections
0.657 0.342 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.654 0.346 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.654 0.346 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.651 0.349 0.000
Z95.4 Presence of other heart-valve replacement
0.651 0.349 0.000
Z95.3 Presence of xenogenic heart valve
0.651 0.349 0.000
Z95.2 Presence of prosthetic heart valve
0.651 0.349 0.000
Z95.0 Presence of cardiac pacemaker
0.651 0.349 0.000
Z95.1 Presence of aortocoronary bypass graft
0.649 0.351 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.648 0.352 0.000
M91-M94 Chondropathies
0.648 0.352 0.000
M86-M90 Other osteopathies
0.648 0.352 0.000
M80-M85 Disorders of bone density and structure
0.648 0.352 0.000
M65-M68 Disorders of synovium and tendon
0.648 0.352 0.000
M60-M63 Disorders of muscles
0.648 0.352 0.000
M40-M43 Deforming dorsopathies
0.648 0.352 0.000
M00-M03 Infectious arthropathies
0.648 0.352 0.000
F99-F99 Unspecified mental disorder
0.647 0.353 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.647 0.353 0.000
F80-F89 Disorders of psychological development
0.647 0.353 0.000
F70-F79 Mental retardation
0.647 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.647 0.353 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.647 0.353 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.647 0.353 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.647 0.353 0.000
R07.1 Chest pain on breathing
0.646 0.353 0.000
R07.0 Pain in throat
0.646 0.353 0.000
I52 Other heart disorders in diseases classified elsewhere
0.646 0.353 0.000
I51 Complications and ill-defined descriptions of heart disease
0.646 0.353 0.000
I49 Other cardiac arrhythmias
0.646 0.353 0.000
I48 Atrial fibrillation and flutter
0.646 0.353 0.000
I46 Cardiac arrest
0.646 0.353 0.000
I45 Other conduction disorders
0.646 0.353 0.000
I44 Atrioventricular and left bundle-branch block
0.646 0.353 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.646 0.353 0.000
I42 Cardiomyopathy
0.646 0.353 0.000
I41 Myocarditis in diseases classified elsewhere
0.646 0.353 0.000
I40 Acute myocarditis
0.646 0.353 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.646 0.353 0.000
I37 Pulmonary valve disorders
0.646 0.353 0.000
I36 Nonrheumatic tricuspid valve disorders
0.646 0.353 0.000
I35 Nonrheumatic aortic valve disorders
0.646 0.353 0.000
I34 Nonrheumatic mitral valve disorders
0.646 0.353 0.000
I33 Acute and subacute endocarditis
0.646 0.353 0.000
I32 Pericarditis in diseases classified elsewhere
0.646 0.353 0.000
I31 Other diseases of pericardium
0.646 0.353 0.000
I30 Acute pericarditis
0.646 0.353 0.000
I38 Endocarditis, valve unspecified
0.646 0.353 0.000
R04.0 Epistaxis
0.645 0.354 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.645 0.355 0.000
E50-E64 Other nutritional deficiencies
0.645 0.355 0.000
E40-E46 Malnutrition
0.645 0.355 0.000
E20-E35 Disorders of other endocrine glands
0.645 0.355 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.645 0.355 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.644 0.355 0.000
R17 Unspecified jaundice
0.644 0.355 0.000
R15 Faecal incontinence
0.644 0.355 0.000
R14 Flatulence and related conditions
0.644 0.355 0.000
R51 Headache
0.642 0.358 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.641 0.359 0.000
M70-M79 Other soft tissue disorders
0.640 0.359 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.639 0.361 0.000
J90-J94 Other diseases of pleura
0.637 0.363 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.637 0.363 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.636 0.364 0.000
F32 Depressive episode
0.635 0.364 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.635 0.365 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.634 0.366 0.000
N37 Urethral disorders in diseases classified elsewhere
0.632 0.368 0.000
N36 Other disorders of urethra
0.632 0.368 0.000
N34 Urethritis and urethral syndrome
0.632 0.368 0.000
N33 Bladder disorders in diseases classified elsewhere
0.632 0.368 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.632 0.368 0.000
N30 Cystitis
0.632 0.368 0.000
Z47 Other orthopaedic follow-up care
0.632 0.368 0.000
Z92.9 Personal history of medical treatment, unspecified
0.630 0.370 0.000
Z92.8 Personal history of other medical treatment
0.630 0.370 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.630 0.370 0.000
Z92.5 Personal history of rehabilitation measures
0.630 0.370 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.630 0.370 0.000
Z92.0 Personal history of contraception
0.630 0.370 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.629 0.371 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.629 0.371 0.000
J60-J70 Lung diseases due to external agents
0.629 0.371 0.000
J00-J06 Acute upper respiratory infections
0.629 0.371 0.000
E65-E68 Obesity and other hyperalimentation
0.629 0.371 0.000
K70-K77 Diseases of liver
0.628 0.372 0.000
Z46 Fitting and adjustment of other devices
0.628 0.372 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.627 0.373 0.000
N32.8 Other specified disorders of bladder
0.625 0.375 0.000
Z60 Problems related to social environment
0.624 0.376 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.623 0.376 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.623 0.376 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.623 0.376 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.623 0.376 0.000
Z82.3 Family history of stroke
0.623 0.376 0.000
Z82.2 Family history of deafness and hearing loss
0.623 0.376 0.000
Z82.1 Family history of blindness and visual loss
0.623 0.376 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.623 0.376 0.000
Z96.1 Presence of intraocular lens
0.623 0.377 0.000
Z54 Convalescence
0.621 0.379 0.000
Z52 Donors of organs and tissues
0.621 0.379 0.000
Z50 Care involving use of rehabilitation procedures
0.621 0.379 0.000
Z49 Care involving dialysis
0.621 0.379 0.000
Z48 Other surgical follow-up care
0.621 0.379 0.000
Z45 Adjustment and management of implanted device
0.621 0.379 0.000
Z44 Fitting and adjustment of external prosthetic device
0.621 0.379 0.000
Z43 Attention to artificial openings
0.621 0.379 0.000
Z42 Follow-up care involving plastic surgery
0.621 0.379 0.000
Z41 Procedures for purposes other than remedying health state
0.621 0.379 0.000
Z40 Prophylactic surgery
0.621 0.379 0.000
H34 Retinal vascular occlusions
0.618 0.382 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.618 0.382 0.000
H31 Other disorders of choroid
0.618 0.382 0.000
H30 Chorioretinal inflammation
0.618 0.382 0.000
K50-K52 Noninfective enteritis and colitis
0.618 0.382 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.617 0.383 0.000
K57 Diverticular disease of intestine
0.614 0.386 0.000
K60 Fissure and fistula of anal and rectal regions
0.614 0.386 0.000
Z12 Special screening examination for neoplasms
0.614 0.386 0.000
E03 Other hypothyroidism
0.614 0.386 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.614 0.386 0.000
R10 Abdominal and pelvic pain
0.612 0.388 0.000
I50.1 Left ventricular failure
0.612 0.388 0.000
J45 Asthma
0.611 0.389 0.000
I22.8 Subsequent myocardial infarction of other sites
0.611 0.389 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.611 0.389 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.611 0.389 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.611 0.389 0.000
J30-J39 Other diseases of upper respiratory tract
0.610 0.390 0.000
R63.4 Abnormal weight loss
0.608 0.392 0.000
R04.2 Haemoptysis
0.607 0.393 0.000
M19 Other arthrosis
0.606 0.394 0.000
C50-C50 Malignant neoplasm of breast
0.601 0.398 0.000
R46 Symptoms and signs involving appearance and behaviour
0.601 0.399 0.000
R45 Symptoms and signs involving emotional state
0.601 0.399 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.601 0.399 0.000
R43 Disturbances of smell and taste
0.601 0.399 0.000
R40 Somnolence, stupor and coma
0.601 0.399 0.000
M13 Other arthritis
0.600 0.400 0.000
K58 Irritable bowel syndrome
0.600 0.400 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.598 0.402 0.000
D00-D09 In situ neoplasms
0.598 0.402 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.598 0.402 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.598 0.402 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.598 0.402 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.598 0.402 0.000
C64-C68 Malignant neoplasms of urinary tract
0.598 0.402 0.000
C51-C58 Malignant neoplasms of female genital organs
0.598 0.402 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.598 0.402 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.598 0.402 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.598 0.402 0.000
C15-C26 Malignant neoplasms of digestive organs
0.598 0.402 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.598 0.402 0.000
H25 Senile cataract
0.598 0.402 0.000
N17 Acute renal failure
0.597 0.403 0.000
K65-K67 Diseases of peritoneum
0.596 0.404 0.000
K35-K38 Diseases of appendix
0.596 0.404 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.594 0.406 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.594 0.406 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.594 0.406 0.000
R77 Other abnormalities of plasma proteins
0.594 0.406 0.000
R76 Other abnormal immunological findings in serum
0.594 0.406 0.000
R74 Abnormal serum enzyme levels
0.594 0.406 0.000
R73 Elevated blood glucose level
0.594 0.406 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.594 0.406 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.594 0.406 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.594 0.406 0.000
R71 Abnormality of red blood cells
0.594 0.406 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.591 0.409 0.000
Z01.8 Other specified special examinations
0.591 0.409 0.000
N41 Inflammatory diseases of prostate
0.591 0.409 0.000
N20 Calculus of kidney and ureter
0.590 0.410 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.590 0.410 0.000
N18 Chronic renal failure
0.588 0.412 0.000
D60-D64 Aplastic and other anaemias
0.587 0.413 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.585 0.415 0.000
R94 Abnormal results of function studies
0.584 0.416 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.584 0.416 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.584 0.416 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.584 0.416 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.584 0.416 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.584 0.416 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.584 0.416 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.584 0.416 0.000
Y35-Y36 Legal intervention and operations of war
0.584 0.416 0.000
Y10-Y34 Event of undetermined intent
0.584 0.416 0.000
Y00-Y09 Assault
0.584 0.416 0.000
X85-X99 Assault
0.584 0.416 0.000
X60-X84 Intentional self-harm
0.584 0.416 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.584 0.416 0.000
X50-X57 Overexertion, travel and privation
0.584 0.416 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.584 0.416 0.000
X30-X39 Exposure to forces of nature
0.584 0.416 0.000
X20-X29 Contact with venomous animals and plants
0.584 0.416 0.000
X10-X19 Contact with heat and hot substances
0.584 0.416 0.000
X00-X09 Exposure to smoke, fire and flames
0.584 0.416 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.584 0.416 0.000
W75-W84 Other accidental threats to breathing
0.584 0.416 0.000
W65-W74 Accidental drowning and submersion
0.584 0.416 0.000
W50-W64 Exposure to animate mechanical forces
0.584 0.416 0.000
W20-W49 Exposure to inanimate mechanical forces
0.584 0.416 0.000
W00-W19 Falls
0.584 0.416 0.000
V98-V99 Other and unspecified transport accidents
0.584 0.416 0.000
V95-V97 Air and space transport accidents
0.584 0.416 0.000
V90-V94 Water transport accidents
0.584 0.416 0.000
V80-V89 Other land transport accidents
0.584 0.416 0.000
V70-V79 Bus occupant injured in transport accident
0.584 0.416 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.584 0.416 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.584 0.416 0.000
V40-V49 Car occupant injured in transport accident
0.584 0.416 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.584 0.416 0.000
V20-V29 Motorcycle rider injured in transport accident
0.584 0.416 0.000
V10-V19 Pedal cyclist injured in transport accident
0.584 0.416 0.000
V01-V09 Pedestrian injured in transport accident
0.584 0.416 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.583 0.416 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.583 0.416 0.000
R19.6 Halitosis
0.583 0.416 0.000
R19.5 Other fecal abnormalities
0.583 0.416 0.000
R19.3 Abdominal rigidity
0.583 0.416 0.000
R19.2 Visible peristalsis
0.583 0.416 0.000
R19.1 Abnormal bowel sounds
0.583 0.416 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.583 0.416 0.000
R03.1 Nonspecific low blood-pressure reading
0.583 0.417 0.000
R21 Rash and other nonspecific skin eruption
0.583 0.417 0.000
C60-C63 Malignant neoplasms of male genital organs
0.582 0.418 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.581 0.419 0.000
F10.1 Harmful use
0.580 0.420 0.000
D50-D53 Nutritional anaemias
0.579 0.421 0.000
R13 Dysphagia
0.579 0.421 0.000
I21.9 Acute myocardial infarction, unspecified
0.576 0.424 0.000
I10-I15 Hypertensive diseases
0.575 0.424 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.574 0.426 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.574 0.426 0.000
Z53.9 Procedure not carried out, unspecified reason
0.574 0.426 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.574 0.426 0.000
I47.0 Reentry ventricular arrhythmia
0.574 0.426 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.573 0.426 0.000
Z72 Problems related to lifestyle
0.573 0.426 0.000
K90-K93 Other diseases of the digestive system
0.573 0.427 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.572 0.428 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.572 0.428 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.572 0.428 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.572 0.428 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.572 0.428 0.000
R04.1 Haemorrhage from throat
0.572 0.428 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.569 0.430 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.569 0.430 0.000
Z09.4 Follow-up examination after treatment of fracture
0.569 0.430 0.000
Z09.3 Follow-up examination after psychotherapy
0.569 0.430 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.569 0.430 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.569 0.430 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.568 0.432 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.568 0.432 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.568 0.432 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.568 0.432 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.568 0.432 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.568 0.432 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.568 0.432 0.000
F11 Mental and behavioural disorders due to use of opioids
0.568 0.432 0.000
S60-S69 Injuries to the wrist and hand
0.567 0.433 0.000
I95 Hypotension
0.567 0.433 0.000
F10.2 Dependence syndrome
0.566 0.434 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.566 0.434 0.000
R50.8 Other specified fever
0.566 0.434 0.000
R50.2 Drug-induced fever
0.566 0.434 0.000
R50.1 Persistent fever
0.566 0.434 0.000
R50.0 Fever with chills
0.566 0.434 0.000
J47 Bronchiectasis
0.566 0.434 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.565 0.435 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.565 0.435 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.565 0.435 0.000
Z85.6 Personal history of leukaemia
0.565 0.435 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.565 0.435 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.565 0.435 0.000
N39.3 Stress incontinence
0.562 0.438 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.561 0.438 0.000
K61 Abscess of anal and rectal regions
0.561 0.438 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.561 0.438 0.000
K55 Vascular disorders of intestine
0.561 0.438 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.561 0.439 0.000
H35.9 Retinal disorder, unspecified
0.561 0.439 0.000
H35.7 Separation of retinal layers
0.561 0.439 0.000
H35.6 Retinal haemorrhage
0.561 0.439 0.000
H35.5 Hereditary retinal dystrophy
0.561 0.439 0.000
H35.4 Peripheral retinal degeneration
0.561 0.439 0.000
H35.2 Other proliferative retinopathy
0.561 0.439 0.000
H35.1 Retinopathy of prematurity
0.561 0.439 0.000
H35.0 Background retinopathy and retinal vascular changes
0.561 0.439 0.000
Z65 Problems related to other psychosocial circumstances
0.560 0.440 0.000
Z64 Problems related to certain psychosocial circumstances
0.560 0.440 0.000
Z63 Other problems related to primary support group, including family circumstances
0.560 0.440 0.000
Z62 Other problems related to upbringing
0.560 0.440 0.000
Z61 Problems related to negative life events in childhood
0.560 0.440 0.000
Z59 Problems related to housing and economic circumstances
0.560 0.440 0.000
Z58 Problems related to physical environment
0.560 0.440 0.000
Z57 Occupational exposure to risk-factors
0.560 0.440 0.000
Z56 Problems related to employment and unemployment
0.560 0.440 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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