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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142089946
log Bayes Factor = 13.9816
Chromosome 5   position 60,791,593  (GRCh37) Explore rs142089946 on Ensembl!
Variant rs142089946 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.992 0.008 0.000
D60-D64 Aplastic and other anaemias
0.989 0.011 0.000
I44.0 Atrioventricular block, first degree
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.985 0.015 0.000
I34 Nonrheumatic mitral valve disorders
0.981 0.019 0.000
I77 Other disorders of arteries and arterioles
0.977 0.023 0.000
M06 Other rheumatoid arthritis
0.976 0.024 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.975 0.025 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.972 0.028 0.000
I78 Diseases of capillaries
0.967 0.033 0.000
M72 Fibroblastic disorders
0.960 0.040 0.000
I77.1 Stricture of artery
0.960 0.040 0.000
D64 Other anaemias
0.952 0.048 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.951 0.049 0.000
D62 Acute posthaemorrhagic anaemia
0.951 0.049 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.950 0.050 0.000
M06.0 Seronegative rheumatoid arthritis
0.949 0.051 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.949 0.051 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.946 0.054 0.000
I60-I69 Cerebrovascular diseases
0.944 0.056 0.000
F41 Other anxiety disorders
0.943 0.057 0.000
D80-D89 Certain disorders involving the immune mechanism
0.939 0.061 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.939 0.061 0.000
I78.1 Naevus, nonneoplastic
0.938 0.062 0.000
F30-F39 Mood [affective] disorders
0.934 0.066 0.000
I25.2 Old myocardial infarction
0.933 0.067 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.930 0.070 0.000
R00.1 Bradycardia, unspecified
0.929 0.071 0.000
I34.1 Mitral (valve) prolapse
0.927 0.073 0.000
D64.9 Anaemia, unspecified
0.925 0.075 0.000
F41.2 Mixed anxiety and depressive disorder
0.920 0.080 0.000
I34.0 Mitral (valve) insufficiency
0.919 0.081 0.000
F00 Dementia in Alzheimer's disease
0.919 0.081 0.000
I51 Complications and ill-defined descriptions of heart disease
0.914 0.086 0.000
R00 Abnormalities of heart beat
0.914 0.086 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.908 0.092 0.000
Chapter VIII Diseases of the ear and mastoid process
0.906 0.094 0.000
I71 Aortic aneurysm and dissection
0.905 0.095 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.905 0.095 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.904 0.096 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.903 0.097 0.000
M77 Other enthesopathies
0.901 0.099 0.000
M80-M85 Disorders of bone density and structure
0.901 0.099 0.000
Y57 Other and unspecified drugs and medicaments
0.895 0.105 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.894 0.106 0.000
M72.2 Plantar fascial fibromatosis
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.885 0.115 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.883 0.117 0.000
I05-I09 Chronic rheumatic heart diseases
0.881 0.119 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.880 0.120 0.000
D86 Sarcoidosis
0.876 0.124 0.000
I35 Nonrheumatic aortic valve disorders
0.873 0.127 0.000
Y48 Anaesthetics and therapeutic gases
0.873 0.127 0.000
M06.9 Rheumatoid arthritis, unspecified
0.869 0.131 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.864 0.136 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.863 0.137 0.000
I67 Other cerebrovascular diseases
0.862 0.138 0.000
T90 Sequelae of injuries of head
0.860 0.140 0.000
M05 Seropositive rheumatoid arthritis
0.860 0.140 0.000
Y42.7 Androgens and anabolic congeners
0.859 0.141 0.000
F43 Reaction to severe stress, and adjustment disorders
0.857 0.143 0.000
F31 Bipolar affective disorder
0.857 0.143 0.000
X50-X57 Overexertion, travel and privation
0.856 0.144 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.855 0.145 0.000
M71 Other bursopathies
0.851 0.149 0.000
M79.0 Rheumatism, unspecified
0.850 0.150 0.000
M79.2 Neuralgia and neuritis, unspecified
0.847 0.153 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.846 0.153 0.000
I62 Other nontraumatic intracranial haemorrhage
0.846 0.154 0.000
M86-M90 Other osteopathies
0.843 0.157 0.000
I35.0 Aortic (valve) stenosis
0.840 0.160 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.839 0.160 0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot
0.838 0.162 0.000
H60-H62 Diseases of external ear
0.837 0.163 0.000
D86.0 Sarcoidosis of lung
0.834 0.166 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.833 0.167 0.000
E10-E14 Diabetes mellitus
0.831 0.169 0.000
F03 Unspecified dementia
0.829 0.171 0.000
I10-I15 Hypertensive diseases
0.829 0.171 0.000
D55-D59 Haemolytic anaemias
0.827 0.173 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.827 0.173 0.000
T93 Sequelae of injuries of lower limb
0.827 0.173 0.000
I51.7 Cardiomegaly
0.826 0.174 0.000
F80-F89 Disorders of psychological development
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.825 0.175 0.000
E11 Non-insulin-dependent diabetes mellitus
0.824 0.176 0.000
T43.2 Other and unspecified antidepressants
0.824 0.176 0.000
M50-M54 Other dorsopathies
0.824 0.176 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.822 0.178 0.000
I60 Subarachnoid haemorrhage
0.822 0.178 0.000
D61 Other aplastic anaemias
0.820 0.180 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.820 0.180 0.000
M80 Osteoporosis with pathological fracture
0.817 0.183 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.816 0.184 0.000
S50-S59 Injuries to the elbow and forearm
0.812 0.188 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.812 0.188 0.000
I25.3 Aneurysm of heart
0.809 0.191 0.000
F60-F69 Disorders of adult personality and behaviour
0.808 0.192 0.000
E20-E35 Disorders of other endocrine glands
0.804 0.196 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.803 0.197 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.801 0.199 0.000
I44.2 Atrioventricular block, complete
0.801 0.199 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.800 0.200 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.796 0.204 0.000
I20 Angina pectoris
0.796 0.204 0.000
M50 Cervical disk disorders
0.795 0.205 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.794 0.206 0.000
I45 Other conduction disorders
0.792 0.208 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.792 0.208 0.000
M15-M19 Arthrosis
0.791 0.209 0.000
R47-R49 Symptoms and signs involving speech and voice
0.790 0.210 0.000
R15 Faecal incontinence
0.790 0.210 0.000
I31 Other diseases of pericardium
0.789 0.211 0.000
F43.2 Adjustment disorders
0.789 0.211 0.000
I72 Other aneurysm
0.788 0.212 0.000
E11.3 With ophthalmic complications
0.787 0.213 0.000
F33 Recurrent depressive disorder
0.787 0.213 0.000
Y54.3 Benzothiadiazine derivatives
0.783 0.217 0.000
R03.1 Nonspecific low blood-pressure reading
0.783 0.217 0.000
R00.0 Tachycardia, unspecified
0.782 0.218 0.000
M79.7 Fibromyalgia
0.782 0.218 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
M76 Enthesopathies of lower limb, excluding foot
0.781 0.219 0.000
Y54.5 Other diuretics
0.781 0.219 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.780 0.220 0.000
Y54.8 Agents affecting uric acid metabolism
0.780 0.220 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.777 0.223 0.000
M18 Arthrosis of first carpometacarpal joint
0.777 0.223 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.776 0.224 0.000
F02 Dementia in other diseases classified elsewhere
0.775 0.225 0.000
I73 Other peripheral vascular diseases
0.774 0.226 0.000
H90-H95 Other disorders of ear
0.774 0.226 0.000
E70-E90 Metabolic disorders
0.773 0.227 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.773 0.227 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.773 0.227 0.000
M79.8 Other specified soft tissue disorders
0.773 0.227 0.000
Y57.5 X-ray contrast media
0.772 0.228 0.000
I46 Cardiac arrest
0.771 0.229 0.000
D50-D53 Nutritional anaemias
0.771 0.229 0.000
I25.1 Atherosclerotic heart disease
0.770 0.230 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.769 0.231 0.000
M12 Other specific arthropathies
0.768 0.232 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.767 0.233 0.000
I08 Multiple valve diseases
0.767 0.233 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.767 0.233 0.000
Chapter VII Diseases of the eye and adnexa
0.766 0.234 0.000
I67.9 Cerebrovascular disease, unspecified
0.765 0.235 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.764 0.236 0.000
M71.3 Other bursal cyst
0.762 0.238 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.761 0.239 0.000
I44.6 Other and unspecified fascicular block
0.761 0.239 0.000
H60 Otitis externa
0.758 0.242 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.758 0.242 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.758 0.242 0.000
M77.9 Enthesopathy, unspecified
0.758 0.242 0.000
Y48.3 Local anaesthetics
0.757 0.243 0.000
I70 Atherosclerosis
0.757 0.243 0.000
T90.4 Sequelae of injury of eye and orbit
0.757 0.243 0.000
M07 Psoriatic and enteropathic arthropathies
0.755 0.245 0.000
M77.0 Medial epicondylitis
0.755 0.245 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.755 0.245 0.000
I38 Endocarditis, valve unspecified
0.755 0.245 0.000
Chapter VI Diseases of the nervous system
0.752 0.248 0.000
F45 Somatoform disorders
0.752 0.248 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.752 0.248 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.751 0.249 0.000
T91 Sequelae of injuries of neck and trunk
0.750 0.250 0.000
T92 Sequelae of injuries of upper limb
0.750 0.250 0.000
F31.9 Bipolar affective disorder, unspecified
0.749 0.251 0.000
I25.5 Ischaemic cardiomyopathy
0.749 0.251 0.000
Y54.4 Loop [high-ceiling] diuretics
0.748 0.252 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.748 0.252 0.000
E86 Volume depletion
0.748 0.252 0.000
I23 Certain current complications following acute myocardial infarction
0.748 0.252 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.748 0.252 0.000
D80 Immunodeficiency with predominantly antibody defects
0.746 0.254 0.000
I10 Essential (primary) hypertension
0.746 0.254 0.000
X20-X29 Contact with venomous animals and plants
0.746 0.254 0.000
M50.2 Other cervical disk displacement
0.745 0.255 0.000
E11.5 With peripheral circulatory complications
0.745 0.255 0.000
R19.4 Change in bowel habit
0.745 0.255 0.000
W50-W64 Exposure to animate mechanical forces
0.744 0.256 0.000
T90.9 Sequelae of unspecified injury of head
0.744 0.256 0.000
Y57.9 Drug or medicament, unspecified
0.743 0.257 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.743 0.257 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
M84 Disorders of continuity of bone
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.739 0.261 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.739 0.261 0.000
D83 Common variable immunodeficiency
0.737 0.263 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.736 0.264 0.000
I77.8 Other specified disorders of arteries and arterioles
0.736 0.264 0.000
M06.3 Rheumatoid nodule
0.735 0.265 0.000
Y00-Y09 Assault
0.735 0.265 0.000
M77.1 Lateral epicondylitis
0.734 0.266 0.000
I51.6 Cardiovascular disease, unspecified
0.733 0.267 0.000
I77.6 Arteritis, unspecified
0.731 0.269 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.730 0.270 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.729 0.271 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.728 0.272 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.727 0.273 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.727 0.273 0.000
E11.4 With neurological complications
0.727 0.273 0.000
X51 Travel and motion
0.726 0.274 0.000
H90 Conductive and sensorineural hearing loss
0.724 0.276 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.724 0.276 0.000
V20-V29 Motorcycle rider injured in transport accident
0.722 0.278 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.722 0.278 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.721 0.279 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.721 0.279 0.000
Q60-Q64 Congenital malformations of the urinary system
0.721 0.279 0.000
I99 Other and unspecified disorders of circulatory system
0.721 0.279 0.000
I20.9 Angina pectoris, unspecified
0.720 0.280 0.000
I77.0 Arteriovenous fistula, acquired
0.718 0.281 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.719 0.281 0.000
M60-M63 Disorders of muscles
0.718 0.281 0.000
R01 Cardiac murmurs and other cardiac sounds
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.284 0.000
Y58 Bacterial vaccines
0.715 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.284 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.715 0.284 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.284 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.715 0.285 0.000
Y42.5 Other oestrogens and progestogens
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.714 0.286 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.713 0.287 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.712 0.288 0.000
I22 Subsequent myocardial infarction
0.712 0.288 0.000
I67.1 Cerebral aneurysm, nonruptured
0.711 0.289 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.289 0.000
I44.5 Left posterior fascicular block
0.711 0.289 0.000
I44.4 Left anterior fascicular block
0.711 0.289 0.000
R02 Gangrene, not elsewhere classified
0.710 0.290 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.290 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
M45-M49 Spondylopathies
0.707 0.293 0.000
I67.8 Other specified cerebrovascular diseases
0.707 0.293 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.704 0.296 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.703 0.297 0.000
I77.5 Necrosis of artery
0.701 0.299 0.000
I77.4 Coeliac artery compression syndrome
0.701 0.299 0.000
I77.3 Arterial fibromuscular dysplasia
0.701 0.299 0.000
I77.2 Rupture of artery
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.700 0.300 0.000
M06.8 Other specified rheumatoid arthritis
0.700 0.300 0.000
M06.2 Rheumatoid bursitis
0.700 0.300 0.000
M06.1 Adult-onset Still's disease
0.700 0.300 0.000
F48 Other neurotic disorders
0.699 0.301 0.000
F44 Dissociative [conversion] disorders
0.699 0.301 0.000
D61.9 Aplastic anaemia, unspecified
0.699 0.301 0.000
I25.4 Coronary artery aneurysm
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.303 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.697 0.303 0.000
F09 Unspecified organic or symptomatic mental disorder
0.697 0.303 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.697 0.303 0.000
M89 Other disorders of bone
0.696 0.303 0.000
F33.9 Recurrent depressive disorder, unspecified
0.696 0.304 0.000
H65-H75 Diseases of middle ear and mastoid
0.695 0.305 0.000
M85 Other disorders of bone density and structure
0.694 0.306 0.000
M06.4 Inflammatory polyarthropathy
0.694 0.306 0.000
F42 Obsessive-compulsive disorder
0.694 0.306 0.000
I78.9 Disease of capillaries, unspecified
0.693 0.307 0.000
I78.8 Other diseases of capillaries
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.693 0.307 0.000
D58 Other hereditary haemolytic anaemias
0.692 0.308 0.000
D50 Iron deficiency anaemia
0.692 0.308 0.000
M00-M03 Infectious arthropathies
0.691 0.309 0.000
F30 Manic episode
0.690 0.310 0.000
F81 Specific developmental disorders of scholastic skills
0.690 0.310 0.000
T14 Injury of unspecified body region
0.689 0.311 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.689 0.311 0.000
M72.9 Fibroblastic disorder, unspecified
0.688 0.311 0.000
M72.8 Other fibroblastic disorders
0.688 0.311 0.000
M72.6 Necrotizing fasciitis
0.688 0.311 0.000
M72.5 Fasciitis, not elsewhere classified
0.688 0.311 0.000
M72.4 Pseudosarcomatous fibromatosis
0.688 0.311 0.000
M72.3 Nodular fasciitis
0.688 0.311 0.000
M72.1 Knuckle pads
0.688 0.311 0.000
I07 Rheumatic tricuspid valve diseases
0.688 0.312 0.000
M10 Gout
0.687 0.313 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.687 0.313 0.000
R14 Flatulence and related conditions
0.686 0.314 0.000
I73.0 Raynaud's syndrome
0.685 0.315 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.685 0.315 0.000
H61 Other disorders of external ear
0.685 0.315 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.685 0.315 0.000
H90.5 Sensorineural hearing loss, unspecified
0.684 0.316 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.684 0.316 0.000
M91-M94 Chondropathies
0.684 0.316 0.000
T93.2 Sequelae of other fractures of lower limb
0.683 0.317 0.000
D64.8 Other specified anaemias
0.682 0.318 0.000
D64.4 Congenital dyserythropoietic anaemia
0.682 0.318 0.000
D64.3 Other sideroblastic anaemias
0.682 0.318 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.682 0.318 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.682 0.318 0.000
D64.0 Hereditary sideroblastic anaemia
0.682 0.318 0.000
Y54.9 Mineral salts, not elsewhere classified
0.682 0.318 0.000
Y54.7 Agents affecting calcification
0.682 0.318 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.682 0.318 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.682 0.318 0.000
Y54.0 Mineralocorticoids
0.682 0.318 0.000
Y48.4 Anaesthetic, unspecified
0.682 0.318 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.681 0.319 0.000
Y46.4 Iminostilbenes
0.681 0.319 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.680 0.320 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.680 0.320 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.680 0.320 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.680 0.320 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.680 0.320 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.680 0.320 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.680 0.320 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.680 0.320 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.680 0.320 0.000
T33-T35 Frostbite
0.680 0.320 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.680 0.320 0.000
T00-T07 Injuries involving multiple body regions
0.680 0.320 0.000
M79.1 Myalgia
0.680 0.320 0.000
H40-H42 Glaucoma
0.680 0.320 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.680 0.320 0.000
M79.9 Soft tissue disorder, unspecified
0.678 0.322 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.678 0.322 0.000
M79.3 Panniculitis, unspecified
0.678 0.322 0.000
R12 Heartburn
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.677 0.323 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.677 0.323 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.677 0.323 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.676 0.324 0.000
F41.8 Other specified anxiety disorders
0.676 0.324 0.000
F41.3 Other mixed anxiety disorders
0.676 0.324 0.000
F41.1 Generalised anxiety disorder
0.675 0.325 0.000
S70-S79 Injuries to the hip and thigh
0.675 0.325 0.000
E11.2 With renal complications
0.675 0.325 0.000
M71.38 Other bursal cyst (Other)
0.675 0.325 0.000
S12 Fracture of neck
0.675 0.325 0.000
E23 Hypofunction and other disorders of pituitary gland
0.674 0.326 0.000
D84 Other immunodeficiencies
0.674 0.326 0.000
D82 Immunodeficiency associated with other major defects
0.674 0.326 0.000
D81 Combined immunodeficiencies
0.674 0.326 0.000
Y42.9 Other and unspecified hormone antagonists
0.673 0.327 0.000
Y42.4 Oral contraceptives
0.673 0.327 0.000
Y42.2 Antithyroid drugs
0.673 0.327 0.000
Y42.1 Thyroid hormones and substitutes
0.673 0.327 0.000
F01 Vascular dementia
0.673 0.327 0.000
T45.0 Antiallergic and antiemetic drugs
0.672 0.328 0.000
I45.1 Other and unspecified right bundle-branch block
0.672 0.328 0.000
F60 Specific personality disorders
0.671 0.329 0.000
I51.9 Heart disease, unspecified
0.671 0.329 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.671 0.329 0.000
D86.1 Sarcoidosis of lymph nodes
0.670 0.330 0.000
Y46.2 Hydantoin derivatives
0.670 0.330 0.000
F38 Other mood [affective] disorders
0.670 0.330 0.000
F34 Persistent mood [affective] disorders
0.670 0.330 0.000
F39 Unspecified mood [affective] disorder
0.670 0.330 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.668 0.332 0.000
X50 Overexertion and strenuous or repetitive movements
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.666 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.666 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.666 0.333 0.000
F50 Eating disorders
0.666 0.334 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.665 0.335 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.663 0.336 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.663 0.337 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.663 0.337 0.000
I51.0 Cardiac septal defect, acquired
0.661 0.339 0.000
Q50-Q56 Congenital malformations of genital organs
0.661 0.339 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.661 0.339 0.000
Y86 Sequelae of other accidents
0.661 0.339 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.660 0.340 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.660 0.340 0.000
I33 Acute and subacute endocarditis
0.659 0.341 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.659 0.341 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.659 0.341 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.659 0.341 0.000
I15 Secondary hypertension
0.657 0.343 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.657 0.343 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.656 0.344 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.656 0.344 0.000
I71.0 Dissection of aorta [any part]
0.656 0.344 0.000
I36 Nonrheumatic tricuspid valve disorders
0.656 0.344 0.000
I46.9 Cardiac arrest, unspecified
0.656 0.344 0.000
I51.5 Myocardial degeneration
0.655 0.344 0.000
I51.4 Myocarditis, unspecified
0.655 0.344 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.655 0.344 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.655 0.344 0.000
M50.0 Cervical disk disorder with myelopathy
0.655 0.345 0.000
T13 Other injuries of lower limb, level unspecified
0.654 0.346 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.654 0.346 0.000
E27 Other disorders of adrenal gland
0.654 0.346 0.000
R47 Speech disturbances, not elsewhere classified
0.654 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
M88 Paget's disease of bone [osteitis deformans]
0.653 0.347 0.000
S50 Superficial injury of forearm
0.653 0.347 0.000
F99-F99 Unspecified mental disorder
0.652 0.347 0.000
M11 Other crystal arthropathies
0.652 0.348 0.000
M79.79 Fibromyalgia (Site unspecified)
0.652 0.348 0.000
R49 Voice disturbances
0.651 0.349 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.651 0.349 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.651 0.349 0.000
M77.02 Medial epicondylitis (Upper arm)
0.651 0.349 0.000
I44.3 Other and unspecified atrioventricular block
0.650 0.350 0.000
I47 Paroxysmal tachycardia
0.650 0.350 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.649 0.351 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.649 0.351 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.649 0.351 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.649 0.351 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.649 0.351 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.649 0.351 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.649 0.351 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.649 0.351 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.649 0.351 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.649 0.351 0.000
T36 Poisoning by systemic antibiotics
0.649 0.351 0.000
T92.1 Sequelae of fracture of arm
0.648 0.352 0.000
M90 Osteopathies in diseases classified elsewhere
0.648 0.352 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.646 0.354 0.000
M77.5 Other enthesopathy of foot
0.646 0.354 0.000
M77.3 Calcaneal spur
0.646 0.354 0.000
M77.2 Periarthritis of wrist
0.646 0.354 0.000
M83 Adult osteomalacia
0.646 0.354 0.000
H60.9 Otitis externa, unspecified
0.643 0.357 0.000
I37 Pulmonary valve disorders
0.643 0.357 0.000
S11 Open wound of neck
0.642 0.358 0.000
Y57.8 Other drugs and medicaments
0.642 0.358 0.000
Y57.7 Vitamins, not elsewhere classified
0.642 0.358 0.000
Y57.6 Other diagnostic agents
0.642 0.358 0.000
Y57.4 Pharmaceutical excipients
0.642 0.358 0.000
Y57.3 Alcohol deterrents
0.642 0.358 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.642 0.358 0.000
Y57.1 Lipotropic drugs
0.642 0.358 0.000
Y57.0 Appetite depressants [anorectics]
0.642 0.358 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.642 0.358 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.642 0.358 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.641 0.359 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.641 0.359 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.641 0.359 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.641 0.359 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.641 0.359 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.641 0.359 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.641 0.359 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.641 0.359 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.641 0.359 0.000
Y51.0 Anticholinesterase agents
0.641 0.359 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.640 0.360 0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)
0.639 0.361 0.000
I05 Rheumatic mitral valve diseases
0.639 0.361 0.000
H65 Nonsuppurative otitis media
0.638 0.362 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.638 0.362 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.638 0.362 0.000
M72.29 Plantar fascial fibromatosis-Site unspec
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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