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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142176337
log Bayes Factor = 1.89382
Chromosome 18   position 57,581,487  (GRCh37) Explore rs142176337 on Ensembl!
Variant rs142176337 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.985 0.015 0.000
I20-I25 Ischaemic heart diseases
0.980 0.020 0.000
I51 Complications and ill-defined descriptions of heart disease
0.975 0.025 0.000
# Top node
0.974 0.026 0.000
I51.7 Cardiomegaly
0.966 0.034 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.944 0.056 0.000
Chapter XX External causes of morbidity and mortality
0.941 0.059 0.000
I25 Chronic ischaemic heart disease
0.934 0.066 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.928 0.072 0.000
I20 Angina pectoris
0.919 0.081 0.000
I50 Heart failure
0.908 0.092 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.897 0.103 0.000
Chapter X Diseases of the respiratory system
0.880 0.120 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.880 0.120 0.000
I44 Atrioventricular and left bundle-branch block
0.874 0.126 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.869 0.131 0.000
Chapter XXI Factors influencing health status and contact with health services
0.867 0.133 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.860 0.140 0.000
J40-J47 Chronic lower respiratory diseases
0.858 0.142 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.848 0.152 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.844 0.156 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.838 0.162 0.000
J44 Other chronic obstructive pulmonary disease
0.834 0.166 0.000
I20.0 Unstable angina
0.832 0.168 0.000
I49 Other cardiac arrhythmias
0.830 0.170 0.000
I21 Acute myocardial infarction
0.826 0.174 0.000
I25.1 Atherosclerotic heart disease
0.825 0.175 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.818 0.182 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.818 0.182 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.818 0.182 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.818 0.182 0.000
S00-S09 Injuries to the head
0.818 0.182 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.812 0.188 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
Chapter I Certain infectious and parasitic diseases
0.801 0.199 0.000
I20.9 Angina pectoris, unspecified
0.797 0.203 0.000
I45 Other conduction disorders
0.797 0.203 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.795 0.205 0.000
I24 Other acute ischaemic heart diseases
0.793 0.207 0.000
I35 Nonrheumatic aortic valve disorders
0.789 0.211 0.000
I25.2 Old myocardial infarction
0.785 0.215 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.782 0.218 0.000
I50.1 Left ventricular failure
0.780 0.220 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.772 0.228 0.000
I50.9 Heart failure, unspecified
0.768 0.232 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.765 0.235 0.000
I44.7 Left bundle-branch block, unspecified
0.762 0.238 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.758 0.242 0.000
I05-I09 Chronic rheumatic heart diseases
0.757 0.243 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.755 0.244 0.000
O00-O08 Pregnancy with abortive outcome
0.754 0.246 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.751 0.249 0.000
I21.9 Acute myocardial infarction, unspecified
0.751 0.249 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.750 0.250 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.749 0.251 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.748 0.252 0.000
I47 Paroxysmal tachycardia
0.747 0.253 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.741 0.259 0.000
I25.5 Ischaemic cardiomyopathy
0.739 0.261 0.000
I51.8 Other ill-defined heart diseases
0.735 0.265 0.000
S60-S69 Injuries to the wrist and hand
0.735 0.265 0.000
V10-V19 Pedal cyclist injured in transport accident
0.731 0.269 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
L60-L75 Disorders of skin appendages
0.725 0.275 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.723 0.277 0.000
I34 Nonrheumatic mitral valve disorders
0.722 0.278 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.722 0.278 0.000
J30-J39 Other diseases of upper respiratory tract
0.718 0.282 0.000
I51.9 Heart disease, unspecified
0.717 0.283 0.000
J45 Asthma
0.716 0.284 0.000
Y83.4 Other reconstructive surgery
0.714 0.286 0.000
Chapter VI Diseases of the nervous system
0.709 0.291 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
I31 Other diseases of pericardium
0.707 0.293 0.000
I30 Acute pericarditis
0.707 0.293 0.000
I38 Endocarditis, valve unspecified
0.707 0.293 0.000
I00-I02 Acute rheumatic fever
0.706 0.294 0.000
I23 Certain current complications following acute myocardial infarction
0.703 0.297 0.000
I22 Subsequent myocardial infarction
0.703 0.297 0.000
I50.0 Congestive heart failure
0.702 0.298 0.000
T82.1 Mechanical complication of cardiac electronic device
0.700 0.300 0.000
I51.6 Cardiovascular disease, unspecified
0.699 0.301 0.000
I51.5 Myocardial degeneration
0.699 0.301 0.000
I51.4 Myocarditis, unspecified
0.699 0.301 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.699 0.301 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.699 0.301 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.699 0.301 0.000
I51.0 Cardiac septal defect, acquired
0.699 0.301 0.000
Chapter XXII Codes for special purposes
0.698 0.302 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.698 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
S80-S89 Injuries to the knee and lower leg
0.695 0.305 0.000
I49.5 Sick sinus syndrome
0.694 0.306 0.000
A00-A09 Intestinal infectious diseases
0.694 0.306 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.692 0.308 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.691 0.309 0.000
D60-D64 Aplastic and other anaemias
0.689 0.311 0.000
W00-W19 Falls
0.689 0.311 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.687 0.313 0.000
I46 Cardiac arrest
0.686 0.314 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.685 0.315 0.000
T79-T79 Certain early complications of trauma
0.685 0.315 0.000
T66-T78 Other and unspecified effects of external causes
0.685 0.315 0.000
T33-T35 Frostbite
0.685 0.315 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.685 0.315 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.685 0.315 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.685 0.315 0.000
T00-T07 Injuries involving multiple body regions
0.685 0.315 0.000
S10-S19 Injuries to the neck
0.685 0.315 0.000
S01 Open wound of head
0.684 0.316 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.681 0.318 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.680 0.320 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.677 0.323 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.677 0.323 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.677 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.323 0.000
T86 Failure and rejection of transplanted organs and tissues
0.677 0.323 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.677 0.323 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.325 0.000
Y35-Y36 Legal intervention and operations of war
0.675 0.325 0.000
Y10-Y34 Event of undetermined intent
0.675 0.325 0.000
Y00-Y09 Assault
0.675 0.325 0.000
X85-X99 Assault
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.675 0.325 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.675 0.325 0.000
X50-X57 Overexertion, travel and privation
0.675 0.325 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.675 0.325 0.000
X30-X39 Exposure to forces of nature
0.675 0.325 0.000
X20-X29 Contact with venomous animals and plants
0.675 0.325 0.000
X10-X19 Contact with heat and hot substances
0.675 0.325 0.000
X00-X09 Exposure to smoke, fire and flames
0.675 0.325 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.675 0.325 0.000
W75-W84 Other accidental threats to breathing
0.675 0.325 0.000
W65-W74 Accidental drowning and submersion
0.675 0.325 0.000
W50-W64 Exposure to animate mechanical forces
0.675 0.325 0.000
W20-W49 Exposure to inanimate mechanical forces
0.675 0.325 0.000
V98-V99 Other and unspecified transport accidents
0.675 0.325 0.000
V95-V97 Air and space transport accidents
0.675 0.325 0.000
V90-V94 Water transport accidents
0.675 0.325 0.000
V80-V89 Other land transport accidents
0.675 0.325 0.000
V70-V79 Bus occupant injured in transport accident
0.675 0.325 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.675 0.325 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.675 0.325 0.000
V40-V49 Car occupant injured in transport accident
0.675 0.325 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
V01-V09 Pedestrian injured in transport accident
0.675 0.325 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.674 0.326 0.000
S00 Superficial injury of head
0.672 0.328 0.000
I44.2 Atrioventricular block, complete
0.669 0.330 0.000
I25.6 Silent myocardial ischaemia
0.669 0.331 0.000
I25.4 Coronary artery aneurysm
0.669 0.331 0.000
I25.3 Aneurysm of heart
0.669 0.331 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.669 0.331 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.667 0.333 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.665 0.334 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.665 0.334 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.665 0.334 0.000
O80-O84 Delivery
0.665 0.335 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.665 0.335 0.000
S20-S29 Injuries to the thorax
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.662 0.338 0.000
Chapter VIII Diseases of the ear and mastoid process
0.662 0.338 0.000
J46 Status asthmaticus
0.662 0.338 0.000
I44.0 Atrioventricular block, first degree
0.662 0.338 0.000
I45.1 Other and unspecified right bundle-branch block
0.661 0.339 0.000
J33 Nasal polyp
0.660 0.340 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.660 0.340 0.000
I24.8 Other forms of acute ischaemic heart disease
0.659 0.341 0.000
I20.1 Angina pectoris with documented spasm
0.659 0.341 0.000
A30-A49 Other bacterial diseases
0.657 0.343 0.000
D50-D53 Nutritional anaemias
0.656 0.344 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.655 0.345 0.000
I47.2 Ventricular tachycardia
0.648 0.352 0.000
S40-S49 Injuries to the shoulder and upper arm
0.646 0.354 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.645 0.355 0.000
I49.3 Ventricular premature depolarisation
0.644 0.356 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.643 0.357 0.000
A04 Other bacterial intestinal infections
0.642 0.358 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.641 0.359 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.641 0.359 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.640 0.360 0.000
J40 Bronchitis, not specified as acute or chronic
0.640 0.360 0.000
I20.8 Other forms of angina pectoris
0.636 0.364 0.000
I42 Cardiomyopathy
0.634 0.365 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.631 0.369 0.000
O85-O92 Complications predominantly related to the puerperium
0.631 0.369 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.631 0.369 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.631 0.369 0.000
Z03.4 Observation for suspected myocardial infarction
0.630 0.370 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.628 0.372 0.000
I44.6 Other and unspecified fascicular block
0.626 0.373 0.000
I44.5 Left posterior fascicular block
0.626 0.373 0.000
I44.4 Left anterior fascicular block
0.626 0.373 0.000
I44.3 Other and unspecified atrioventricular block
0.626 0.373 0.000
Y83.3 Surgical operation with formation of external stoma
0.625 0.375 0.000
S02 Fracture of skull and facial bones
0.625 0.375 0.000
Y83.9 Surgical procedure, unspecified
0.623 0.377 0.000
Y83.5 Amputation of limb(s)
0.623 0.377 0.000
Y83.0 Surgical operation with transplant of whole organ
0.623 0.377 0.000
Z01.9 Special examination, unspecified
0.622 0.378 0.000
I44.1 Atrioventricular block, second degree
0.622 0.378 0.000
J95-J99 Other diseases of the respiratory system
0.620 0.380 0.000
Z12 Special screening examination for neoplasms
0.619 0.381 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.617 0.383 0.000
J60-J70 Lung diseases due to external agents
0.617 0.383 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.616 0.383 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.616 0.383 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.616 0.383 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.616 0.383 0.000
T82.3 Mechanical complication of other vascular grafts
0.616 0.383 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.616 0.383 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.616 0.383 0.000
J41 Simple and mucopurulent chronic bronchitis
0.615 0.385 0.000
J42 Unspecified chronic bronchitis
0.615 0.385 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.614 0.386 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.608 0.392 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.608 0.392 0.000
L60 Nail disorders
0.607 0.393 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.606 0.394 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.605 0.395 0.000
Z10 Routine general health check-up of defined subpopulation
0.605 0.395 0.000
L50-L54 Urticaria and erythema
0.604 0.396 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.604 0.396 0.000
Chapter V Mental and behavioural disorders
0.603 0.397 0.000
Z01.8 Other specified special examinations
0.602 0.398 0.000
L20-L30 Dermatitis and eczema
0.600 0.400 0.000
O04 Medical abortion
0.599 0.401 0.000
J45.9 Asthma, unspecified
0.598 0.402 0.000
S50-S59 Injuries to the elbow and forearm
0.598 0.402 0.000
J33.9 Nasal polyp, unspecified
0.597 0.403 0.000
S69 Other and unspecified injuries of wrist and hand
0.596 0.404 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.596 0.404 0.000
I49.8 Other specified cardiac arrhythmias
0.595 0.405 0.000
I49.4 Other and unspecified premature depolarisation
0.595 0.405 0.000
I49.2 Junctional premature depolarisation
0.595 0.405 0.000
I49.1 Atrial premature depolarisation
0.595 0.405 0.000
I49.0 Ventricular fibrillation and flutter
0.595 0.405 0.000
J00-J06 Acute upper respiratory infections
0.595 0.405 0.000
O02 Other abnormal products of conception
0.595 0.405 0.000
I08 Multiple valve diseases
0.593 0.407 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.592 0.408 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.592 0.408 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.592 0.408 0.000
I35.1 Aortic (valve) insufficiency
0.592 0.408 0.000
Y52 Agents primarily affecting the cardiovascular system
0.591 0.409 0.000
Z03.3 Observation for suspected nervous system disorder
0.591 0.409 0.000
Y86 Sequelae of other accidents
0.590 0.410 0.000
S01.8 Open wound of other parts of head
0.588 0.412 0.000
Z42 Follow-up care involving plastic surgery
0.587 0.413 0.000
B25-B34 Other viral diseases
0.587 0.413 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.587 0.413 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.587 0.413 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.587 0.413 0.000
Z09.4 Follow-up examination after treatment of fracture
0.587 0.413 0.000
Z09.3 Follow-up examination after psychotherapy
0.587 0.413 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.587 0.413 0.000
S08 Traumatic amputation of part of head
0.586 0.414 0.000
S07 Crushing injury of head
0.586 0.414 0.000
S06 Intracranial injury
0.586 0.414 0.000
S05 Injury of eye and orbit
0.586 0.414 0.000
S04 Injury of cranial nerves
0.586 0.414 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.586 0.414 0.000
D51 Vitamin B12 deficiency anaemia
0.586 0.414 0.000
I49.9 Cardiac arrhythmia, unspecified
0.586 0.414 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.584 0.416 0.000
L10-L14 Bullous disorders
0.582 0.418 0.000
O00 Ectopic pregnancy
0.582 0.418 0.000
Z45 Adjustment and management of implanted device
0.581 0.419 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.580 0.420 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.579 0.421 0.000
S62 Fracture at wrist and hand level
0.578 0.422 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.577 0.423 0.000
D80-D89 Certain disorders involving the immune mechanism
0.575 0.425 0.000
D55-D59 Haemolytic anaemias
0.575 0.425 0.000
B99-B99 Other infectious diseases
0.574 0.425 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.574 0.425 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.574 0.425 0.000
B65-B83 Helminthiases
0.574 0.425 0.000
B50-B64 Protozoal diseases
0.574 0.425 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.574 0.425 0.000
B15-B19 Viral hepatitis
0.574 0.425 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.574 0.425 0.000
A80-A89 Viral infections of the central nervous system
0.574 0.425 0.000
A75-A79 Rickettsioses
0.574 0.425 0.000
A70-A74 Other diseases caused by chlamydiae
0.574 0.425 0.000
A65-A69 Other spirochaetal diseases
0.574 0.425 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.574 0.425 0.000
A20-A28 Certain zoonotic bacterial diseases
0.574 0.425 0.000
A15-A19 Tuberculosis
0.574 0.425 0.000
Z04 Examination and observation for other reasons
0.574 0.426 0.000
Y40 Systemic antibiotics
0.574 0.426 0.000
Z03.8 Observation for other suspected diseases and conditions
0.574 0.426 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.573 0.426 0.000
I45.9 Conduction disorder, unspecified
0.571 0.428 0.000
I45.8 Other specified conduction disorders
0.571 0.428 0.000
I45.6 Preexcitation syndrome
0.571 0.428 0.000
I45.5 Other specified heart block
0.571 0.428 0.000
I45.4 Nonspecific intraventricular block
0.571 0.428 0.000
I45.3 Trifascicular block
0.571 0.428 0.000
I45.2 Bifascicular block
0.571 0.428 0.000
I45.0 Right fascicular block
0.571 0.428 0.000
I35.0 Aortic (valve) stenosis
0.570 0.430 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.569 0.431 0.000
I24.1 Dressler's syndrome
0.569 0.431 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.569 0.431 0.000
Y85 Sequelae of transport accidents
0.567 0.433 0.000
I35.9 Aortic valve disorder, unspecified
0.566 0.434 0.000
I35.8 Other aortic valve disorders
0.566 0.434 0.000
E50-E64 Other nutritional deficiencies
0.564 0.436 0.000
Z34 Supervision of normal pregnancy
0.564 0.436 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.563 0.437 0.000
Z02 Examination and encounter for administrative purposes
0.563 0.437 0.000
G20-G26 Extrapyramidal and movement disorders
0.561 0.439 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.561 0.439 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.561 0.439 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.560 0.440 0.000
T31 Burns classified according to extent of body surface involved
0.560 0.440 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.560 0.440 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.559 0.440 0.000
O36 Maternal care for other known or suspected foetal problems
0.557 0.443 0.000
O60-O75 Complications of labour and delivery
0.556 0.444 0.000
A41 Other septicaemia
0.554 0.446 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.554 0.446 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.554 0.446 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.554 0.446 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.554 0.446 0.000
T85.2 Mechanical complication of intraocular lens
0.554 0.446 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.554 0.446 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.554 0.446 0.000
J47 Bronchiectasis
0.552 0.448 0.000
Z22 Carrier of infectious disease
0.552 0.448 0.000
S00.0 Superficial injury of scalp
0.551 0.449 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.548 0.452 0.000
A04.5 Campylobacter enteritis
0.547 0.453 0.000
O03 Spontaneous abortion
0.547 0.453 0.000
J43 Emphysema
0.546 0.454 0.000
A04.8 Other specified bacterial intestinal infections
0.545 0.455 0.000
Z40 Prophylactic surgery
0.543 0.457 0.000
I09 Other rheumatic heart diseases
0.543 0.457 0.000
I07 Rheumatic tricuspid valve diseases
0.543 0.457 0.000
I06 Rheumatic aortic valve diseases
0.543 0.457 0.000
I05 Rheumatic mitral valve diseases
0.543 0.457 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.542 0.458 0.000
Z01.7 Laboratory examination
0.542 0.458 0.000
Z01.6 Radiological examination, not elsewhere classified
0.542 0.458 0.000
Z01.4 Gynaecological examination (general)(routine)
0.542 0.458 0.000
Z01.3 Examination of blood pressure
0.542 0.458 0.000
Z01.2 Dental examination
0.542 0.458 0.000
Z01.1 Examination of ears and hearing
0.542 0.458 0.000
Z01.0 Examination of eyes and vision
0.542 0.458 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.541 0.459 0.000
O07 Failed attempted abortion
0.541 0.459 0.000
O06 Unspecified abortion
0.541 0.459 0.000
O05 Other abortion
0.541 0.459 0.000
O01 Hydatidiform mole
0.541 0.459 0.000
J45.0 Predominantly allergic asthma
0.540 0.460 0.000
I34.0 Mitral (valve) insufficiency
0.540 0.460 0.000
A08 Viral and other specified intestinal infections
0.539 0.461 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.539 0.461 0.000
Q80-Q89 Other congenital malformations
0.539 0.461 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.539 0.461 0.000
Q60-Q64 Congenital malformations of the urinary system
0.539 0.461 0.000
Q50-Q56 Congenital malformations of genital organs
0.539 0.461 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.539 0.461 0.000
Q35-Q37 Cleft lip and cleft palate
0.539 0.461 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.539 0.461 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.539 0.461 0.000
Q00-Q07 Congenital malformations of the nervous system
0.539 0.461 0.000
Y89 Sequelae of other external causes
0.537 0.462 0.000
Y88 Sequelae of surgical and medical care as external cause
0.537 0.462 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.537 0.462 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.537 0.462 0.000
Y59 Other and unspecified vaccines and biological substances
0.537 0.463 0.000
Y58 Bacterial vaccines
0.537 0.463 0.000
Y57 Other and unspecified drugs and medicaments
0.537 0.463 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.537 0.463 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.537 0.463 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.537 0.463 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.537 0.463 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.537 0.463 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.537 0.463 0.000
Y48 Anaesthetics and therapeutic gases
0.537 0.463 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.537 0.463 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.537 0.463 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.537 0.463 0.000
Y44 Agents primarily affecting blood constituents
0.537 0.463 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.537 0.463 0.000
J84 Other interstitial pulmonary diseases
0.537 0.463 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.536 0.464 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.536 0.464 0.000
Z03.0 Observation for suspected tuberculosis
0.536 0.464 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.535 0.464 0.000
I47.0 Reentry ventricular arrhythmia
0.535 0.464 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.535 0.464 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.535 0.465 0.000
D64 Other anaemias
0.533 0.467 0.000
J35 Chronic diseases of tonsils and adenoids
0.533 0.467 0.000
G40-G47 Episodic and paroxysmal disorders
0.532 0.468 0.000
J33.8 Other polyp of sinus
0.531 0.468 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.531 0.469 0.000
O97 Death from sequelae of direct obstetric causes
0.531 0.469 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.531 0.469 0.000
O95 Obstetric death of unspecified cause
0.531 0.469 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.531 0.469 0.000
Y83.6 Removal of other organ (partial) (total)
0.531 0.469 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.531 0.469 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.530 0.470 0.000
L72.0 Epidermal cyst
0.530 0.470 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.527 0.473 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.527 0.473 0.000
S68 Traumatic amputation of wrist and hand
0.527 0.473 0.000
S67 Crushing injury of wrist and hand
0.527 0.473 0.000
S65 Injury of blood vessels at wrist and hand level
0.527 0.473 0.000
S64 Injury of nerves at wrist and hand level
0.527 0.473 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.527 0.473 0.000
S60 Superficial injury of wrist and hand
0.527 0.473 0.000
D62 Acute posthaemorrhagic anaemia
0.526 0.473 0.000
S00.9 Superficial injury of head, part unspecified
0.526 0.474 0.000
H65-H75 Diseases of middle ear and mastoid
0.525 0.475 0.000
E20-E35 Disorders of other endocrine glands
0.524 0.476 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.524 0.476 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.524 0.476 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.524 0.476 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.524 0.476 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.524 0.476 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.524 0.476 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.524 0.476 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.524 0.476 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.524 0.476 0.000
B35-B49 Mycoses
0.524 0.476 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.524 0.476 0.000
I84 Haemorrhoids
0.522 0.478 0.000
Z48 Other surgical follow-up care
0.522 0.478 0.000
L60.0 Ingrowing nail
0.522 0.478 0.000
Z03.1 Observation for suspected malignant neoplasm
0.521 0.479 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.520 0.480 0.000
T32 Corrosions classified according to extent of body surface involved
0.520 0.480 0.000
T30 Burn and corrosion, body region unspecified
0.520 0.480 0.000
T29 Burns and corrosions of multiple body regions
0.520 0.480 0.000
I21.4 Acute subendocardial myocardial infarction
0.520 0.480 0.000
L75 Apocrine sweat disorders
0.520 0.480 0.000
L74 Eccrine sweat disorders
0.520 0.480 0.000
L73 Other follicular disorders
0.520 0.480 0.000
L71 Rosacea
0.520 0.480 0.000
L70 Acne
0.520 0.480 0.000
L68 Hypertrichosis
0.520 0.480 0.000
L67 Hair colour and hair shaft abnormalities
0.520 0.480 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.520 0.480 0.000
L65 Other nonscarring hair loss
0.520 0.480 0.000
L64 Androgenic alopecia
0.520 0.480 0.000
L63 Alopecia areata
0.520 0.480 0.000
L62 Nail disorders in diseases classified elsewhere
0.520 0.480 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.518 0.481 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.518 0.482 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.518 0.482 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.518 0.482 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.517 0.483 0.000
J39 Other diseases of upper respiratory tract
0.515 0.485 0.000
J37 Chronic laryngitis and laryngotracheitis
0.515 0.485 0.000
J36 Peritonsillar abscess
0.515 0.485 0.000
J45.8 Mixed asthma
0.513 0.487 0.000
J45.1 Nonallergic asthma
0.513 0.487 0.000
Z35 Supervision of high-risk pregnancy
0.511 0.489 0.000
O80 Single spontaneous delivery
0.511 0.489 0.000
S92 Fracture of foot, except ankle
0.510 0.489 0.000
M20-M25 Other joint disorders
0.510 0.490 0.000
I77 Other disorders of arteries and arterioles
0.510 0.490 0.000
I34.1 Mitral (valve) prolapse
0.510 0.490 0.000
G70-G73 Diseases of myoneural junction and muscle
0.508 0.491 0.000
G30-G32 Other degenerative diseases of the nervous system
0.508 0.491 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.508 0.491 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.508 0.491 0.000
S82 Fracture of lower leg, including ankle
0.508 0.491 0.000
I60-I69 Cerebrovascular diseases
0.508 0.492 0.000
W19 Unspecified fall
0.508 0.492 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.508 0.492 0.000
I71 Aortic aneurysm and dissection
0.507 0.493 0.000
I30.9 Acute pericarditis, unspecified
0.507 0.493 0.000
I30.8 Other forms of acute pericarditis
0.507 0.493 0.000
I30.1 Infective pericarditis
0.507 0.493 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.507 0.493 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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