TreeWAS – Variant ID: rs142944815

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.997	0.003
Chapter VII Diseases of the eye and adnexa	0.978	0.022
Chapter II Neoplasms	0.969	0.031
Chapter IX Diseases of the circulatory system	0.963	0.037
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.958	0.042
D10-D36 Benign neoplasms	0.950	0.050
Chapter XI Diseases of the digestive system	0.944	0.056
I30-I52 Other forms of heart disease	0.909	0.091
Chapter X Diseases of the respiratory system	0.905	0.095
R50-R69 General symptoms and signs	0.894	0.106
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.890	0.110
K20-K31 Diseases of oesophagus, stomach and duodenum	0.884	0.116
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.879	0.121
I60-I69 Cerebrovascular diseases	0.871	0.129
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.867	0.133
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.865	0.135
D24 Benign neoplasm of breast	0.865	0.135
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.864	0.136
H40-H42 Glaucoma	0.848	0.152
J30-J39 Other diseases of upper respiratory tract	0.844	0.156
K22 Other diseases of oesophagus	0.843	0.157
H53-H54 Visual disturbances and blindness	0.839	0.161
Chapter XV Pregnancy, childbirth and the puerperium	0.837	0.163
R69 Unknown and unspecified causes of morbidity	0.831	0.169
Chapter XII Diseases of the skin and subcutaneous tissue	0.827	0.173
H25-H28 Disorders of lens	0.820	0.180
I20-I25 Ischaemic heart diseases	0.795	0.205
D12.3 Transverse colon	0.795	0.205
R42 Dizziness and giddiness	0.793	0.207
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.790	0.210
Chapter VIII Diseases of the ear and mastoid process	0.784	0.216
C15-C26 Malignant neoplasms of digestive organs	0.783	0.217
R63 Symptoms and signs concerning food and fluid intake	0.783	0.217
I50 Heart failure	0.781	0.219
J40-J47 Chronic lower respiratory diseases	0.779	0.221
I44 Atrioventricular and left bundle-branch block	0.771	0.229
D50-D53 Nutritional anaemias	0.768	0.232
K50-K52 Noninfective enteritis and colitis	0.764	0.236
D23 Other benign neoplasms of skin	0.763	0.237
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.762	0.238
K22.1 Ulcer of oesophagus	0.762	0.238
C50-C50 Malignant neoplasm of breast	0.761	0.239
R47-R49 Symptoms and signs involving speech and voice	0.756	0.244
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.754	0.246
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.754	0.246
H40 Glaucoma	0.754	0.246
Chapter XX External causes of morbidity and mortality	0.751	0.249
M20-M25 Other joint disorders	0.746	0.253
I51 Complications and ill-defined descriptions of heart disease	0.742	0.258
D18 Haemangioma and lymphangioma, any site	0.742	0.258
C64-C68 Malignant neoplasms of urinary tract	0.741	0.259
K35-K38 Diseases of appendix	0.741	0.259
Chapter XIV Diseases of the genitourinary system	0.740	0.259
K22.7 Barrett's oesophagus	0.736	0.264
H02 Other disorders of eyelid	0.734	0.266
I63 Cerebral infarction	0.731	0.269
D12.8 Rectum	0.730	0.270
K90-K93 Other diseases of the digestive system	0.729	0.271
H30-H36 Disorders of choroid and retina	0.724	0.276
D12.0 Caecum	0.717	0.283
Chapter XXII Codes for special purposes	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
D00-D09 In situ neoplasms	0.713	0.287
I35 Nonrheumatic aortic valve disorders	0.712	0.288
K31 Other diseases of stomach and duodenum	0.711	0.289
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.710	0.290
M50-M54 Other dorsopathies	0.708	0.292
I25 Chronic ischaemic heart disease	0.707	0.293
H00 Hordeolum and chalazion	0.707	0.293
D25 Leiomyoma of uterus	0.705	0.295
R30-R39 Symptoms and signs involving the urinary system	0.705	0.295
R63.4 Abnormal weight loss	0.704	0.295
I50.0 Congestive heart failure	0.704	0.296
J33 Nasal polyp	0.702	0.298
H55-H59 Other disorders of eye and adnexa	0.701	0.298
H46-H48 Disorders of optic nerve and visual pathways	0.701	0.298
H43-H45 Disorders of vitreous body and globe	0.701	0.298
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.701	0.298
H10-H13 Disorders of conjunctiva	0.701	0.298
I64 Stroke, not specified as haemorrhage or infarction	0.700	0.300
R56 Convulsions, not elsewhere classified	0.699	0.300
D60-D64 Aplastic and other anaemias	0.698	0.302
D37-D48 Neoplasms of uncertain or unknown behaviour	0.695	0.305
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.695	0.305
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.695	0.305
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.695	0.305
C51-C58 Malignant neoplasms of female genital organs	0.695	0.305
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.695	0.305
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.695	0.305
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.693	0.307
I31 Other diseases of pericardium	0.693	0.307
I95-I99 Other and unspecified disorders of the circulatory system	0.691	0.309
I05-I09 Chronic rheumatic heart diseases	0.690	0.310
I00-I02 Acute rheumatic fever	0.690	0.310
I70-I79 Diseases of arteries, arterioles and capillaries	0.690	0.310
H25 Senile cataract	0.690	0.310
R61 Hyperhidrosis	0.690	0.310
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.689	0.311
D80-D89 Certain disorders involving the immune mechanism	0.689	0.311
I42 Cardiomyopathy	0.688	0.311
D50 Iron deficiency anaemia	0.688	0.312
J80-J84 Other respiratory diseases principally affecting the interstitium	0.687	0.313
R95-R99 Ill-defined and unknown causes of mortality	0.687	0.313
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.687	0.313
H54 Blindness and low vision	0.685	0.315
H53 Visual disturbances	0.684	0.315
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.684	0.316
Chapter IV Endocrine, nutritional and metabolic diseases	0.684	0.316
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.683	0.317
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.683	0.317
D17 Benign lipomatous neoplasm	0.681	0.318
M45-M49 Spondylopathies	0.681	0.319
D36 Benign neoplasm of other and unspecified sites	0.681	0.319
D35 Benign neoplasm of other and unspecified endocrine glands	0.681	0.319
D33 Benign neoplasm of brain and other parts of central nervous system	0.681	0.319
D32 Benign neoplasm of meninges	0.681	0.319
D31 Benign neoplasm of eye and adnexa	0.681	0.319
D30 Benign neoplasm of urinary organs	0.681	0.319
D29 Benign neoplasm of male genital organs	0.681	0.319
D28 Benign neoplasm of other and unspecified female genital organs	0.681	0.319
D26 Other benign neoplasms of uterus	0.681	0.319
D21 Other benign neoplasms of connective and other soft tissue	0.681	0.319
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.681	0.319
D19 Benign neoplasm of mesothelial tissue	0.681	0.319
D16 Benign neoplasm of bone and articular cartilage	0.681	0.319
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.681	0.319
D14 Benign neoplasm of middle ear and respiratory system	0.681	0.319
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.681	0.319
D11 Benign neoplasm of major salivary glands	0.681	0.319
D10 Benign neoplasm of mouth and pharynx	0.681	0.319
D34 Benign neoplasm of thyroid gland	0.681	0.319
J44 Other chronic obstructive pulmonary disease	0.679	0.321
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.676	0.323
Chapter V Mental and behavioural disorders	0.673	0.327
I67 Other cerebrovascular diseases	0.669	0.331
K30 Dyspepsia	0.669	0.331
D12.5 Sigmoid colon	0.667	0.333
D12.2 Ascending colon	0.667	0.333
J32 Chronic sinusitis	0.662	0.338
L40-L45 Papulosquamous disorders	0.662	0.338
K22.8 Other specified diseases of oesophagus	0.660	0.340
I49 Other cardiac arrhythmias	0.660	0.340
J34 Other disorders of nose and nasal sinuses	0.658	0.342
K08 Other disorders of teeth and supporting structures	0.656	0.344
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.654	0.346
K20 Oesophagitis	0.653	0.347
I69 Sequelae of cerebrovascular disease	0.652	0.348
I52 Other heart disorders in diseases classified elsewhere	0.652	0.348
I48 Atrial fibrillation and flutter	0.652	0.348
I46 Cardiac arrest	0.652	0.348
I43 Cardiomyopathy in diseases classified elsewhere	0.652	0.348
I41 Myocarditis in diseases classified elsewhere	0.652	0.348
I40 Acute myocarditis	0.652	0.348
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.652	0.348
I37 Pulmonary valve disorders	0.652	0.348
I36 Nonrheumatic tricuspid valve disorders	0.652	0.348
I33 Acute and subacute endocarditis	0.652	0.348
I32 Pericarditis in diseases classified elsewhere	0.652	0.348
I30 Acute pericarditis	0.652	0.348
I38 Endocarditis, valve unspecified	0.652	0.348
C43-C44 Melanoma and other malignant neoplasms of skin	0.652	0.348
Chapter VI Diseases of the nervous system	0.651	0.349
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.649	0.351
J60-J70 Lung diseases due to external agents	0.649	0.351
J00-J06 Acute upper respiratory infections	0.649	0.351
R41 Other symptoms and signs involving cognitive functions and awareness	0.649	0.351
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.649	0.351
O60-O75 Complications of labour and delivery	0.648	0.352
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.647	0.353
O94-O99 Other obstetric conditions, not elsewhere classified	0.647	0.353
K51 Ulcerative colitis	0.646	0.354
J09-J18 Influenza and pneumonia	0.645	0.355
J40 Bronchitis, not specified as acute or chronic	0.645	0.355
M05-M14 Inflammatory polyarthropathies	0.645	0.355
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.643	0.357
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.642	0.358
M40-M43 Deforming dorsopathies	0.641	0.359
R68 Other general symptoms and signs	0.641	0.359
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.641	0.359
R62 Lack of expected normal physiological development	0.641	0.359
R60 Oedema, not elsewhere classified	0.641	0.359
R57 Shock, not elsewhere classified	0.641	0.359
R52 Pain, not elsewhere classified	0.641	0.359
R64 Cachexia	0.641	0.359
R58 Haemorrhage, not elsewhere classified	0.641	0.359
R54 Senility	0.641	0.359
O80-O84 Delivery	0.641	0.359
K55-K64 Other diseases of intestines	0.641	0.359
L60-L75 Disorders of skin appendages	0.640	0.360
K26 Duodenal ulcer	0.640	0.360
K65-K67 Diseases of peritoneum	0.639	0.360
C18 Malignant neoplasm of colon	0.638	0.362
D12.9 Anus and anal canal	0.638	0.362
D12.7 Rectosigmoid junction	0.638	0.362
D12.4 Descending colon	0.638	0.362
D12.1 Appendix	0.638	0.362
R53 Malaise and fatigue	0.638	0.362
H40.9 Glaucoma, unspecified	0.636	0.364
K28 Gastrojejunal ulcer	0.634	0.366
K27 Peptic ulcer, site unspecified	0.634	0.366
K23 Disorders of oesophagus in diseases classified elsewhere	0.634	0.366
H04 Disorders of lachrymal system	0.633	0.367
K70-K77 Diseases of liver	0.632	0.367
L20-L30 Dermatitis and eczema	0.632	0.368
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.631	0.369
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.630	0.370
D55-D59 Haemolytic anaemias	0.630	0.370
I44.0 Atrioventricular block, first degree	0.628	0.372
N25-N29 Other disorders of kidney and ureter	0.627	0.372
D22 Melanocytic naevi	0.627	0.373
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.626	0.374
I68 Cerebrovascular disorders in diseases classified elsewhere	0.625	0.375
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.625	0.375
I62 Other nontraumatic intracranial haemorrhage	0.625	0.375
I61 Intracerebral haemorrhage	0.625	0.375
I60 Subarachnoid haemorrhage	0.625	0.375
M20 Acquired deformities of fingers and toes	0.624	0.376
D27 Benign neoplasm of ovary	0.624	0.376
I25.9 Chronic ischaemic heart disease, unspecified	0.624	0.376
H02.4 Ptosis of eyelid	0.622	0.378
R87 Abnormal findings in specimens from female genital organs	0.622	0.378
R46 Symptoms and signs involving appearance and behaviour	0.621	0.378
R45 Symptoms and signs involving emotional state	0.621	0.378
R44 Other symptoms and signs involving general sensations and perceptions	0.621	0.378
R43 Disturbances of smell and taste	0.621	0.378
R40 Somnolence, stupor and coma	0.621	0.378
I44.7 Left bundle-branch block, unspecified	0.621	0.379
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.620	0.379
H05 Disorders of orbit	0.620	0.379
H03 Disorders of eyelid in diseases classified elsewhere	0.620	0.379
H01 Other inflammation of eyelid	0.620	0.379
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.619	0.380
M91-M94 Chondropathies	0.619	0.380
M86-M90 Other osteopathies	0.619	0.380
M60-M63 Disorders of muscles	0.619	0.380
M00-M03 Infectious arthropathies	0.619	0.380
I34 Nonrheumatic mitral valve disorders	0.619	0.381
M65-M68 Disorders of synovium and tendon	0.619	0.381
N80-N98 Noninflammatory disorders of female genital tract	0.619	0.381
H26 Other cataract	0.616	0.384
K40-K46 Hernia	0.616	0.384
H25.1 Senile nuclear cataract	0.615	0.385
M80-M85 Disorders of bone density and structure	0.615	0.385
K02 Dental caries	0.615	0.385
C50 Malignant neoplasm of breast	0.611	0.388
R47 Speech disturbances, not elsewhere classified	0.611	0.389
O00-O08 Pregnancy with abortive outcome	0.611	0.389
I51.8 Other ill-defined heart diseases	0.611	0.389
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.611	0.389
H42 Glaucoma in diseases classified elsewhere	0.608	0.392
H80-H83 Diseases of inner ear	0.607	0.392
I47 Paroxysmal tachycardia	0.607	0.393
J39 Other diseases of upper respiratory tract	0.605	0.395
J37 Chronic laryngitis and laryngotracheitis	0.605	0.395
J35 Chronic diseases of tonsils and adenoids	0.605	0.395
J30 Vasomotor and allergic rhinitis	0.605	0.395
J36 Peritonsillar abscess	0.605	0.395
Chapter I Certain infectious and parasitic diseases	0.605	0.395
H40.0 Glaucoma suspect	0.605	0.395
I25.2 Old myocardial infarction	0.605	0.395
K22.9 Disease of oesophagus, unspecified	0.605	0.395
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.605	0.395
K22.5 Diverticulum of oesophagus, acquired	0.605	0.395
K22.4 Dyskinesia of oesophagus	0.605	0.395
K22.3 Perforation of oesophagus	0.605	0.395
K22.0 Achalasia of cardia	0.605	0.395
K25 Gastric ulcer	0.604	0.395
J95-J99 Other diseases of the respiratory system	0.602	0.398
W00-W19 Falls	0.602	0.398
J33.9 Nasal polyp, unspecified	0.600	0.399
O85-O92 Complications predominantly related to the puerperium	0.600	0.400
O20-O29 Other maternal disorders predominantly related to pregnancy	0.600	0.400
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.600	0.400
R50 Fever of unknown origin	0.597	0.403
D23.7 Skin of lower limb, including hip	0.597	0.403
K35 Acute appendicitis	0.595	0.405
M31 Other necrotising vasculopathies	0.595	0.405
J47 Bronchiectasis	0.595	0.405
I45 Other conduction disorders	0.593	0.407
H00.1 Chalazion	0.593	0.407
L50-L54 Urticaria and erythema	0.593	0.407
L10-L14 Bullous disorders	0.593	0.407
M70-M79 Other soft tissue disorders	0.592	0.407
D18.0 Haemangioma, any site	0.592	0.408
K22.2 Oesophageal obstruction	0.591	0.408
H90-H95 Other disorders of ear	0.591	0.409
K04 Diseases of pulp and periapical tissues	0.588	0.411
D23.1 Skin of eyelid, including canthus	0.588	0.412
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.588	0.412
H27 Other disorders of lens	0.588	0.412
D50.8 Other iron deficiency anaemias	0.587	0.413
R21 Rash and other nonspecific skin eruption	0.587	0.413
N70-N77 Inflammatory diseases of female pelvic organs	0.586	0.413
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.585	0.415
M24 Other specific joint derangements	0.584	0.416
N99-N99 Other disorders of the genitourinary system	0.581	0.418
C20 Malignant neoplasm of rectum	0.580	0.420
K29 Gastritis and duodenitis	0.580	0.420
Q20-Q28 Congenital malformations of the circulatory system	0.580	0.420
H40.2 Primary angle-closure glaucoma	0.579	0.421
M54 Dorsalgia	0.578	0.422
D50.9 Iron deficiency anaemia, unspecified	0.577	0.423
H54.0 Blindness, both eyes	0.575	0.425
R33 Retention of urine	0.574	0.426
H53.2 Diplopia	0.574	0.426
I35.0 Aortic (valve) stenosis	0.571	0.429
I24 Other acute ischaemic heart diseases	0.570	0.430
I23 Certain current complications following acute myocardial infarction	0.570	0.430
I22 Subsequent myocardial infarction	0.570	0.430
R59 Enlarged lymph nodes	0.570	0.430
N10-N16 Renal tubulo-interstitial diseases	0.570	0.430
D64 Other anaemias	0.569	0.431
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.569	0.431
C64 Malignant neoplasm of kidney, except renal pelvis	0.568	0.431
R20 Disturbances of skin sensation	0.568	0.432
K14 Diseases of tongue	0.567	0.433
K13 Other diseases of lip and oral mucosa	0.567	0.433
K12 Stomatitis and related lesions	0.567	0.433
K11 Diseases of salivary glands	0.567	0.433
K10 Other diseases of jaws	0.567	0.433
K09 Cysts of oral region, not elsewhere classified	0.567	0.433
K07 Dentofacial anomalies [including malocclusion]	0.567	0.433
K06 Other disorders of gingiva and edentulous alveolar ridge	0.567	0.433
K05 Gingivitis and periodontal diseases	0.567	0.433
K03 Other diseases of hard tissues of teeth	0.567	0.433
K00 Disorders of tooth development and eruption	0.567	0.433
R55 Syncope and collapse	0.565	0.435
H65-H75 Diseases of middle ear and mastoid	0.562	0.438
H60-H62 Diseases of external ear	0.562	0.438
K51.9 Ulcerative colitis, unspecified	0.562	0.438
C26 Malignant neoplasm of other and ill-defined digestive organs	0.562	0.438
C25 Malignant neoplasm of pancreas	0.562	0.438
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.562	0.438
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.562	0.438
C21 Malignant neoplasm of anus and anal canal	0.562	0.438
C17 Malignant neoplasm of small intestine	0.562	0.438
C16 Malignant neoplasm of stomach	0.562	0.438
C15 Malignant neoplasm of oesophagus	0.562	0.438
C23 Malignant neoplasm of gallbladder	0.562	0.438
C19 Malignant neoplasm of rectosigmoid junction	0.562	0.438
R63.8 Other symptoms and signs concerning food and fluid intake	0.562	0.438
R63.6 Insufficient intake of food and water due to self neglect	0.562	0.438
R63.5 Abnormal weight gain	0.562	0.438
R63.3 Feeding difficulties and mismanagement	0.562	0.438
R63.2 Polyphagia	0.562	0.438
R63.1 Polydipsia	0.562	0.438
R63.0 Anorexia	0.562	0.438
K08.3 Retained dental root	0.561	0.439
R56.8 Other and unspecified convulsions	0.560	0.440
K31.8 Other specified diseases of stomach and duodenum	0.560	0.440
I50.9 Heart failure, unspecified	0.560	0.440
R30 Pain associated with micturition	0.559	0.441
I20 Angina pectoris	0.559	0.441
J41 Simple and mucopurulent chronic bronchitis	0.559	0.441
J46 Status asthmaticus	0.559	0.441
J42 Unspecified chronic bronchitis	0.559	0.441
H02.8 Other specified disorders of eyelid	0.558	0.442
K90 Intestinal malabsorption	0.558	0.442
D12.6 Colon, unspecified	0.557	0.443
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.556	0.444
J38.7 Other diseases of larynx	0.554	0.446
I44.6 Other and unspecified fascicular block	0.553	0.447
I44.5 Left posterior fascicular block	0.553	0.447
I44.4 Left anterior fascicular block	0.553	0.447
I44.3 Other and unspecified atrioventricular block	0.553	0.447
I44.2 Atrioventricular block, complete	0.553	0.447
I44.1 Atrioventricular block, second degree	0.553	0.447
J43 Emphysema	0.552	0.448
D86 Sarcoidosis	0.552	0.448
I51.7 Cardiomegaly	0.551	0.449
D53 Other nutritional anaemias	0.550	0.449
D52 Folate deficiency anaemia	0.550	0.449
D51 Vitamin B12 deficiency anaemia	0.550	0.449
L00-L08 Infections of the skin and subcutaneous tissue	0.548	0.452
J20-J22 Other acute lower respiratory infections	0.548	0.452
K52 Other non-infective gastro-enteritis and colitis	0.548	0.452
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.547	0.452
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.547	0.453
D23.9 Skin, unspecified	0.547	0.453
D23.6 Skin of upper limb, including shoulder	0.547	0.453
D23.5 Skin of trunk	0.547	0.453
D23.4 Skin of scalp and neck	0.547	0.453
D23.3 Skin of other and unspecified parts of face	0.547	0.453
D23.2 Skin of ear and external auricular canal	0.547	0.453
D23.0 Skin of lip	0.547	0.453
N28 Other disorders of kidney and ureter, not elsewhere classified	0.547	0.453
R89 Abnormal findings in specimens from other organs, systems and tissues	0.546	0.453
R86 Abnormal findings in specimens from male genital organs	0.546	0.453
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.546	0.453
R84 Abnormal findings in specimens from respiratory organs and thorax	0.546	0.453
R83 Abnormal findings in cerebrospinal fluid	0.546	0.453
R51 Headache	0.546	0.454
K31.7 Polyp of stomach and duodenum	0.545	0.454
N92 Excessive, frequent and irregular menstruation	0.543	0.457
R61.9 Hyperhidrosis, unspecified	0.543	0.457
L40 Psoriasis	0.543	0.457
K92 Other diseases of digestive system	0.543	0.457
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.543	0.457
R49 Voice disturbances	0.542	0.458
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.542	0.458
C67 Malignant neoplasm of bladder	0.541	0.458
R23 Other skin changes	0.541	0.459
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.541	0.459
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.541	0.459
Q80-Q89 Other congenital malformations	0.541	0.459
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.541	0.459
Q60-Q64 Congenital malformations of the urinary system	0.541	0.459
Q50-Q56 Congenital malformations of genital organs	0.541	0.459
Q38-Q45 Other congenital malformations of the digestive system	0.541	0.459
Q35-Q37 Cleft lip and cleft palate	0.541	0.459
Q30-Q34 Congenital malformations of the respiratory system	0.541	0.459
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.541	0.459
Q00-Q07 Congenital malformations of the nervous system	0.541	0.459
H40.8 Other glaucoma	0.541	0.459
H40.6 Glaucoma secondary to drugs	0.541	0.459
H40.5 Glaucoma secondary to other eye disorders	0.541	0.459
H40.4 Glaucoma secondary to eye inflammation	0.541	0.459
H40.3 Glaucoma secondary to eye trauma	0.541	0.459
H40.1 Primary open-angle glaucoma	0.541	0.459
J38.3 Other diseases of vocal cords	0.540	0.460
L80-L99 Other disorders of the skin and subcutaneous tissue	0.539	0.461
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.539	0.461
Y60-Y69 Misadventures to patients during surgical and medical care	0.539	0.461
Y35-Y36 Legal intervention and operations of war	0.539	0.461
Y10-Y34 Event of undetermined intent	0.539	0.461
Y00-Y09 Assault	0.539	0.461
X85-X99 Assault	0.539	0.461
X60-X84 Intentional self-harm	0.539	0.461
X58-X59 Accidental exposure to other and unspecified factors	0.539	0.461
X50-X57 Overexertion, travel and privation	0.539	0.461
X40-X49 Accidental poisoning by and exposure to noxious substances	0.539	0.461
X30-X39 Exposure to forces of nature	0.539	0.461
X20-X29 Contact with venomous animals and plants	0.539	0.461
X10-X19 Contact with heat and hot substances	0.539	0.461
X00-X09 Exposure to smoke, fire and flames	0.539	0.461
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.539	0.461
W75-W84 Other accidental threats to breathing	0.539	0.461
W65-W74 Accidental drowning and submersion	0.539	0.461
W50-W64 Exposure to animate mechanical forces	0.539	0.461
W20-W49 Exposure to inanimate mechanical forces	0.539	0.461
V98-V99 Other and unspecified transport accidents	0.539	0.461
V95-V97 Air and space transport accidents	0.539	0.461
V90-V94 Water transport accidents	0.539	0.461
V80-V89 Other land transport accidents	0.539	0.461
V70-V79 Bus occupant injured in transport accident	0.539	0.461
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.539	0.461
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.539	0.461
V40-V49 Car occupant injured in transport accident	0.539	0.461
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.539	0.461
V20-V29 Motorcycle rider injured in transport accident	0.539	0.461
V10-V19 Pedal cyclist injured in transport accident	0.539	0.461
V01-V09 Pedestrian injured in transport accident	0.539	0.461
D70-D77 Other diseases of blood and blood-forming organs	0.538	0.462
M20.5 Other deformities of toe(s) (acquired)	0.538	0.462
M47 Spondylosis	0.538	0.462
I31.3 Pericardial effusion (noninflammatory)	0.537	0.462
M51 Other intervertebral disk disorders	0.536	0.464
N17-N19 Renal failure	0.536	0.464
S00-S09 Injuries to the head	0.535	0.464
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.535	0.465
M35 Other systemic involvement of connective tissue	0.535	0.465
M34 Systemic sclerosis	0.535	0.465
M33 Dermatopolymyositis	0.535	0.465
M32 Systemic lupus erythematosus	0.535	0.465
M30 Polyarteritis nodosa and related conditions	0.535	0.465
M22 Disorders of patella	0.535	0.465
M21 Other acquired deformities of limbs	0.535	0.465
C18.7 Sigmoid colon	0.534	0.465
J34.3 Hypertrophy of nasal turbinates	0.534	0.465
D17.6 Benign lipomatous neoplasm of spermatic cord	0.534	0.466
E50-E64 Other nutritional deficiencies	0.534	0.466
H35 Other retinal disorders	0.533	0.467
I51.9 Heart disease, unspecified	0.532	0.468
I51.6 Cardiovascular disease, unspecified	0.532	0.468
I51.5 Myocardial degeneration	0.532	0.468
I51.4 Myocarditis, unspecified	0.532	0.468
I51.3 Intracardiac thrombosis, not elsewhere classified	0.532	0.468
I51.2 Rupture of papillary muscle, not elsewhere classified	0.532	0.468
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.532	0.468
I51.0 Cardiac septal defect, acquired	0.532	0.468
H33 Retinal detachments and breaks	0.532	0.468
J32.9 Chronic sinusitis, unspecified	0.532	0.468
D18.1 Lymphangioma, any site	0.532	0.468
J84 Other interstitial pulmonary diseases	0.531	0.469
C68 Malignant neoplasm of other and unspecified urinary organs	0.531	0.469
C66 Malignant neoplasm of ureter	0.531	0.469
C65 Malignant neoplasm of renal pelvis	0.531	0.469
K38 Other diseases of appendix	0.531	0.469
K37 Unspecified appendicitis	0.531	0.469
K36 Other appendicitis	0.531	0.469
N00-N08 Glomerular diseases	0.531	0.469
K01 Embedded and impacted teeth	0.531	0.469
I42.0 Dilated cardiomyopathy	0.530	0.469
K21 Gastro-oesophageal reflux disease	0.530	0.470
F40-F48 Neurotic, stress-related and somatoform disorders	0.530	0.470
N81 Female genital prolapse	0.529	0.471
D05 Carcinoma in situ of breast	0.529	0.471
K63 Other diseases of intestine	0.528	0.472

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations