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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs145669774
log Bayes Factor = 5.67804
Chromosome 3   position 185,545,502  (GRCh37) Explore rs145669774 on Ensembl!
Variant rs145669774 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.989 0.011 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
Chapter X Diseases of the respiratory system
0.976 0.024 0.000
Chapter XIV Diseases of the genitourinary system
0.976 0.024 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.971 0.029 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.971 0.029 0.000
I60-I69 Cerebrovascular diseases
0.964 0.036 0.000
N17-N19 Renal failure
0.952 0.048 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.928 0.072 0.000
N18 Chronic renal failure
0.926 0.074 0.000
D60-D64 Aplastic and other anaemias
0.924 0.076 0.000
N40-N51 Diseases of male genital organs
0.920 0.080 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.920 0.080 0.000
I63 Cerebral infarction
0.915 0.085 0.000
J95-J99 Other diseases of the respiratory system
0.898 0.102 0.000
I51 Complications and ill-defined descriptions of heart disease
0.897 0.103 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.890 0.110 0.000
D64 Other anaemias
0.889 0.111 0.000
Chapter V Mental and behavioural disorders
0.888 0.112 0.000
I44 Atrioventricular and left bundle-branch block
0.887 0.113 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.885 0.115 0.000
Chapter XX External causes of morbidity and mortality
0.883 0.117 0.000
I47 Paroxysmal tachycardia
0.880 0.120 0.000
O60-O75 Complications of labour and delivery
0.873 0.127 0.000
E65-E68 Obesity and other hyperalimentation
0.871 0.129 0.000
D64.9 Anaemia, unspecified
0.864 0.136 0.000
I63.9 Cerebral infarction, unspecified
0.859 0.141 0.000
I50 Heart failure
0.853 0.147 0.000
N48 Other disorders of penis
0.850 0.150 0.000
J98 Other respiratory disorders
0.842 0.158 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.840 0.160 0.000
I51.7 Cardiomegaly
0.838 0.162 0.000
E66 Obesity
0.835 0.165 0.000
J40-J47 Chronic lower respiratory diseases
0.833 0.167 0.000
I34 Nonrheumatic mitral valve disorders
0.831 0.169 0.000
N18.9 Chronic renal failure, unspecified
0.831 0.169 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.830 0.170 0.000
N50 Other disorders of male genital organs
0.830 0.170 0.000
M05-M14 Inflammatory polyarthropathies
0.829 0.171 0.000
A30-A49 Other bacterial diseases
0.827 0.173 0.000
S20-S29 Injuries to the thorax
0.827 0.173 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.826 0.174 0.000
N10-N16 Renal tubulo-interstitial diseases
0.826 0.174 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.826 0.174 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.825 0.175 0.000
M15-M19 Arthrosis
0.823 0.177 0.000
N00-N08 Glomerular diseases
0.820 0.180 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.820 0.180 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
I46 Cardiac arrest
0.805 0.195 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.803 0.197 0.000
B95-B98 Bacterial, viral and other infectious agents
0.800 0.200 0.000
M45-M49 Spondylopathies
0.798 0.202 0.000
E66.9 Obesity, unspecified
0.798 0.202 0.000
Chapter VI Diseases of the nervous system
0.793 0.207 0.000
I67 Other cerebrovascular diseases
0.792 0.207 0.000
N99-N99 Other disorders of the genitourinary system
0.789 0.211 0.000
M19 Other arthrosis
0.788 0.212 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.785 0.215 0.000
J90-J94 Other diseases of pleura
0.781 0.219 0.000
S60-S69 Injuries to the wrist and hand
0.780 0.220 0.000
J09-J18 Influenza and pneumonia
0.778 0.222 0.000
D80-D89 Certain disorders involving the immune mechanism
0.775 0.225 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.775 0.225 0.000
L03 Cellulitis
0.775 0.225 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.774 0.226 0.000
I69 Sequelae of cerebrovascular disease
0.774 0.226 0.000
M20-M25 Other joint disorders
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.773 0.227 0.000
E10-E14 Diabetes mellitus
0.773 0.227 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.770 0.230 0.000
I30 Acute pericarditis
0.770 0.230 0.000
I47.1 Supraventricular tachycardia
0.766 0.234 0.000
N18.4 Chronic kidney disease, stage 4
0.766 0.234 0.000
N19 Unspecified renal failure
0.765 0.235 0.000
M19.9 Arthrosis, unspecified
0.763 0.237 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.763 0.237 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.762 0.238 0.000
I50.0 Congestive heart failure
0.759 0.241 0.000
N18.0 End-stage renal disease
0.758 0.242 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.756 0.244 0.000
A41 Other septicaemia
0.755 0.245 0.000
S00-S09 Injuries to the head
0.753 0.247 0.000
O36 Maternal care for other known or suspected foetal problems
0.753 0.247 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.250 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.748 0.252 0.000
O72 Postpartum haemorrhage
0.746 0.254 0.000
N13 Obstructive and reflux uropathy
0.745 0.255 0.000
Chapter II Neoplasms
0.744 0.256 0.000
N18.5 Chronic kidney disease, stage 5
0.743 0.256 0.000
E20-E35 Disorders of other endocrine glands
0.741 0.259 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.740 0.260 0.000
Chapter XXII Codes for special purposes
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.737 0.263 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.736 0.264 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
I44.6 Other and unspecified fascicular block
0.735 0.265 0.000
N18.3 Chronic kidney disease, stage 3
0.735 0.265 0.000
N50.8 Other specified disorders of male genital organs
0.735 0.265 0.000
N43 Hydrocele and spermatocele
0.734 0.266 0.000
I44.0 Atrioventricular block, first degree
0.733 0.266 0.000
J20-J22 Other acute lower respiratory infections
0.733 0.267 0.000
O80-O84 Delivery
0.730 0.270 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.729 0.271 0.000
S80-S89 Injuries to the knee and lower leg
0.727 0.273 0.000
S50-S59 Injuries to the elbow and forearm
0.726 0.274 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.726 0.274 0.000
M13 Other arthritis
0.722 0.278 0.000
I38 Endocarditis, valve unspecified
0.722 0.278 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.717 0.283 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
I47.2 Ventricular tachycardia
0.715 0.285 0.000
S70-S79 Injuries to the hip and thigh
0.713 0.287 0.000
J60-J70 Lung diseases due to external agents
0.713 0.287 0.000
J98.1 Pulmonary collapse
0.713 0.287 0.000
N48.4 Impotence of organic origin
0.712 0.288 0.000
Chapter XI Diseases of the digestive system
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.709 0.291 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.709 0.291 0.000
Chapter VIII Diseases of the ear and mastoid process
0.709 0.291 0.000
L03.1 Cellulitis of other parts of limb
0.707 0.293 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.707 0.293 0.000
T33-T35 Frostbite
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.293 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
S10-S19 Injuries to the neck
0.707 0.293 0.000
T81 Complications of procedures, not elsewhere classified
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I37 Pulmonary valve disorders
0.706 0.294 0.000
I36 Nonrheumatic tricuspid valve disorders
0.706 0.294 0.000
I33 Acute and subacute endocarditis
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
E10 Insulin-dependent diabetes mellitus
0.704 0.296 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
W20-W49 Exposure to inanimate mechanical forces
0.701 0.299 0.000
I42 Cardiomyopathy
0.701 0.299 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.697 0.303 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.697 0.303 0.000
S40-S49 Injuries to the shoulder and upper arm
0.697 0.303 0.000
N17 Acute renal failure
0.697 0.303 0.000
D55-D59 Haemolytic anaemias
0.696 0.304 0.000
O85-O92 Complications predominantly related to the puerperium
0.696 0.304 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.696 0.304 0.000
I44.1 Atrioventricular block, second degree
0.695 0.305 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.694 0.306 0.000
T86 Failure and rejection of transplanted organs and tissues
0.694 0.306 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.693 0.307 0.000
I05-I09 Chronic rheumatic heart diseases
0.692 0.308 0.000
N48.2 Other inflammatory disorders of penis
0.692 0.308 0.000
B35-B49 Mycoses
0.692 0.308 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.691 0.309 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.691 0.309 0.000
I62 Other nontraumatic intracranial haemorrhage
0.691 0.309 0.000
J98.4 Other disorders of lung
0.691 0.309 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.686 0.314 0.000
I34.1 Mitral (valve) prolapse
0.685 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.685 0.315 0.000
M19.94 Arthrosis, unspecified (Hand)
0.684 0.316 0.000
D68 Other coagulation defects
0.683 0.317 0.000
F30-F39 Mood [affective] disorders
0.683 0.317 0.000
I50.1 Left ventricular failure
0.682 0.317 0.000
M47 Spondylosis
0.681 0.319 0.000
F99-F99 Unspecified mental disorder
0.680 0.320 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
I67.9 Cerebrovascular disease, unspecified
0.679 0.321 0.000
I31 Other diseases of pericardium
0.679 0.321 0.000
T78 Adverse effects, not elsewhere classified
0.678 0.322 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.677 0.323 0.000
I46.0 Cardiac arrest with successful resuscitation
0.676 0.324 0.000
E66.8 Other obesity
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.673 0.327 0.000
M91-M94 Chondropathies
0.673 0.327 0.000
M86-M90 Other osteopathies
0.673 0.327 0.000
M60-M63 Disorders of muscles
0.673 0.327 0.000
M00-M03 Infectious arthropathies
0.673 0.327 0.000
N48.6 Balanitis xerotica obliterans
0.673 0.327 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.328 0.000
S32 Fracture of lumbar spine and pelvis
0.672 0.328 0.000
N50.1 Vascular disorders of male genital organs
0.669 0.330 0.000
A41.9 Septicaemia, unspecified
0.668 0.332 0.000
J40 Bronchitis, not specified as acute or chronic
0.667 0.333 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.667 0.333 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.665 0.335 0.000
B99-B99 Other infectious diseases
0.665 0.335 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.665 0.335 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.665 0.335 0.000
B65-B83 Helminthiases
0.665 0.335 0.000
B50-B64 Protozoal diseases
0.665 0.335 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.665 0.335 0.000
B15-B19 Viral hepatitis
0.665 0.335 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.665 0.335 0.000
A80-A89 Viral infections of the central nervous system
0.665 0.335 0.000
A75-A79 Rickettsioses
0.665 0.335 0.000
A70-A74 Other diseases caused by chlamydiae
0.665 0.335 0.000
A65-A69 Other spirochaetal diseases
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.665 0.335 0.000
A20-A28 Certain zoonotic bacterial diseases
0.665 0.335 0.000
A15-A19 Tuberculosis
0.665 0.335 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.665 0.335 0.000
N25-N29 Other disorders of kidney and ureter
0.664 0.336 0.000
N18.8 Other chronic renal failure
0.664 0.336 0.000
N18.2 Chronic kidney disease, stage 2
0.664 0.336 0.000
N18.1 Chronic kidney disease, stage 1
0.664 0.336 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.663 0.337 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.663 0.337 0.000
D62 Acute posthaemorrhagic anaemia
0.663 0.337 0.000
F17.1 Harmful use
0.662 0.338 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.661 0.339 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.660 0.340 0.000
M23 Internal derangement of knee
0.660 0.340 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.660 0.340 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.660 0.340 0.000
N46 Male infertility
0.660 0.340 0.000
N44 Torsion of testis
0.660 0.340 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
K35-K38 Diseases of appendix
0.660 0.340 0.000
I51.8 Other ill-defined heart diseases
0.658 0.342 0.000
I63.8 Other cerebral infarction
0.656 0.344 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.656 0.344 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.656 0.344 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.656 0.344 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.656 0.344 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.656 0.344 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.656 0.344 0.000
D69 Purpura and other haemorrhagic conditions
0.656 0.344 0.000
I61 Intracerebral haemorrhage
0.655 0.345 0.000
I34.0 Mitral (valve) insufficiency
0.655 0.345 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.655 0.345 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.654 0.345 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.653 0.347 0.000
O26.8 Other specified pregnancy-related conditions
0.653 0.347 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.653 0.347 0.000
N13.3 Other and unspecified hydronephrosis
0.652 0.348 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.652 0.348 0.000
N48.1 Balanoposthitis
0.651 0.348 0.000
Y95 Nosocomial condition
0.651 0.349 0.000
M05 Seropositive rheumatoid arthritis
0.650 0.350 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.650 0.350 0.000
J42 Unspecified chronic bronchitis
0.649 0.351 0.000
I49 Other cardiac arrhythmias
0.646 0.354 0.000
M13.9 Arthritis, unspecified
0.645 0.355 0.000
I44.7 Left bundle-branch block, unspecified
0.645 0.355 0.000
I35 Nonrheumatic aortic valve disorders
0.645 0.355 0.000
S01 Open wound of head
0.644 0.356 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.644 0.356 0.000
J96 Respiratory failure, not elsewhere classified
0.644 0.356 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.644 0.356 0.000
I51.6 Cardiovascular disease, unspecified
0.643 0.356 0.000
I51.5 Myocardial degeneration
0.643 0.356 0.000
I51.4 Myocarditis, unspecified
0.643 0.356 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.643 0.356 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.643 0.356 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.643 0.356 0.000
I51.0 Cardiac septal defect, acquired
0.643 0.356 0.000
N45 Orchitis and epididymitis
0.643 0.357 0.000
E10.9 Without complications
0.642 0.358 0.000
N03 Chronic nephritic syndrome
0.642 0.358 0.000
O00-O08 Pregnancy with abortive outcome
0.642 0.358 0.000
L89 Decubitus ulcer
0.641 0.359 0.000
M25 Other joint disorders, not elsewhere classified
0.640 0.360 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.640 0.360 0.000
M40-M43 Deforming dorsopathies
0.638 0.362 0.000
L50-L54 Urticaria and erythema
0.638 0.362 0.000
L10-L14 Bullous disorders
0.638 0.362 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.638 0.362 0.000
D64.8 Other specified anaemias
0.637 0.362 0.000
D64.4 Congenital dyserythropoietic anaemia
0.637 0.362 0.000
D64.3 Other sideroblastic anaemias
0.637 0.362 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.637 0.362 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.637 0.362 0.000
D64.0 Hereditary sideroblastic anaemia
0.637 0.362 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.636 0.363 0.000
F80-F89 Disorders of psychological development
0.636 0.363 0.000
F70-F79 Mental retardation
0.636 0.363 0.000
F60-F69 Disorders of adult personality and behaviour
0.636 0.363 0.000
I44.5 Left posterior fascicular block
0.636 0.364 0.000
I44.4 Left anterior fascicular block
0.636 0.364 0.000
I44.3 Other and unspecified atrioventricular block
0.636 0.364 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.636 0.364 0.000
D61 Other aplastic anaemias
0.636 0.364 0.000
M06 Other rheumatoid arthritis
0.636 0.364 0.000
J18 Pneumonia, organism unspecified
0.635 0.365 0.000
A00-A09 Intestinal infectious diseases
0.635 0.365 0.000
I60 Subarachnoid haemorrhage
0.635 0.365 0.000
D86 Sarcoidosis
0.635 0.365 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.635 0.365 0.000
T87 Complications peculiar to reattachment and amputation
0.635 0.365 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.635 0.365 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.635 0.365 0.000
L08 Other local infections of skin and subcutaneous tissue
0.635 0.365 0.000
N60-N64 Disorders of breast
0.635 0.365 0.000
I44.2 Atrioventricular block, complete
0.634 0.365 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.633 0.367 0.000
Y35-Y36 Legal intervention and operations of war
0.633 0.367 0.000
Y10-Y34 Event of undetermined intent
0.633 0.367 0.000
Y00-Y09 Assault
0.633 0.367 0.000
X85-X99 Assault
0.633 0.367 0.000
X60-X84 Intentional self-harm
0.633 0.367 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.633 0.367 0.000
X50-X57 Overexertion, travel and privation
0.633 0.367 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.633 0.367 0.000
X30-X39 Exposure to forces of nature
0.633 0.367 0.000
X20-X29 Contact with venomous animals and plants
0.633 0.367 0.000
X10-X19 Contact with heat and hot substances
0.633 0.367 0.000
X00-X09 Exposure to smoke, fire and flames
0.633 0.367 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.633 0.367 0.000
W75-W84 Other accidental threats to breathing
0.633 0.367 0.000
W65-W74 Accidental drowning and submersion
0.633 0.367 0.000
W50-W64 Exposure to animate mechanical forces
0.633 0.367 0.000
V98-V99 Other and unspecified transport accidents
0.633 0.367 0.000
V95-V97 Air and space transport accidents
0.633 0.367 0.000
V90-V94 Water transport accidents
0.633 0.367 0.000
V80-V89 Other land transport accidents
0.633 0.367 0.000
V70-V79 Bus occupant injured in transport accident
0.633 0.367 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.633 0.367 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.633 0.367 0.000
V40-V49 Car occupant injured in transport accident
0.633 0.367 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.633 0.367 0.000
V20-V29 Motorcycle rider injured in transport accident
0.633 0.367 0.000
V01-V09 Pedestrian injured in transport accident
0.633 0.367 0.000
O36.6 Maternal care for excessive foetal growth
0.633 0.367 0.000
N42 Other disorders of prostate
0.632 0.368 0.000
J47 Bronchiectasis
0.631 0.369 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.631 0.369 0.000
I47.0 Reentry ventricular arrhythmia
0.631 0.369 0.000
L20-L30 Dermatitis and eczema
0.630 0.370 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.629 0.371 0.000
V10-V19 Pedal cyclist injured in transport accident
0.628 0.372 0.000
N48.8 Other specified disorders of penis
0.627 0.373 0.000
G90-G99 Other disorders of the nervous system
0.627 0.373 0.000
K35 Acute appendicitis
0.627 0.373 0.000
N76 Other inflammation of vagina and vulva
0.626 0.374 0.000
O74 Complications of anaesthesia during labour and delivery
0.626 0.374 0.000
O73 Retained placenta and membranes, without haemorrhage
0.626 0.374 0.000
O71 Other obstetric trauma
0.626 0.374 0.000
O66 Other obstructed labour
0.626 0.374 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.626 0.374 0.000
O62 Abnormalities of forces of labour
0.626 0.374 0.000
O61 Failed induction of labour
0.626 0.374 0.000
O60 Preterm delivery
0.626 0.374 0.000
J46 Status asthmaticus
0.626 0.374 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.625 0.374 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.625 0.375 0.000
J45 Asthma
0.625 0.375 0.000
O42 Premature rupture of membranes
0.625 0.375 0.000
E67 Other hyperalimentation
0.624 0.376 0.000
E68 Sequelae of hyperalimentation
0.624 0.376 0.000
E65 Localised adiposity
0.624 0.376 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.623 0.377 0.000
N70 Salpingitis and oophoritis
0.622 0.378 0.000
M22 Disorders of patella
0.622 0.378 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.621 0.379 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.621 0.379 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.620 0.380 0.000
I51.9 Heart disease, unspecified
0.617 0.383 0.000
M81 Osteoporosis without pathological fracture
0.617 0.383 0.000
I30.9 Acute pericarditis, unspecified
0.617 0.383 0.000
E50-E64 Other nutritional deficiencies
0.616 0.384 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.616 0.384 0.000
I45 Other conduction disorders
0.615 0.384 0.000
S62 Fracture at wrist and hand level
0.614 0.386 0.000
B25-B34 Other viral diseases
0.612 0.388 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.612 0.388 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.611 0.389 0.000
I10-I15 Hypertensive diseases
0.611 0.389 0.000
J91 Pleural effusion in conditions classified elsewhere
0.610 0.390 0.000
N48.9 Disorder of penis, unspecified
0.609 0.391 0.000
N48.5 Ulcer of penis
0.609 0.391 0.000
N48.3 Priapism
0.609 0.391 0.000
N48.0 Leukoplakia of penis
0.609 0.391 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.607 0.393 0.000
M85 Other disorders of bone density and structure
0.606 0.393 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.606 0.394 0.000
S64 Injury of nerves at wrist and hand level
0.606 0.394 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.605 0.394 0.000
M48 Other spondylopathies
0.605 0.395 0.000
Q50-Q56 Congenital malformations of genital organs
0.605 0.395 0.000
N73 Other female pelvic inflammatory diseases
0.605 0.395 0.000
J98.9 Respiratory disorder, unspecified
0.604 0.396 0.000
J98.8 Other specified respiratory disorders
0.604 0.396 0.000
J98.6 Disorders of diaphragm
0.604 0.396 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.604 0.396 0.000
J98.3 Compensatory emphysema
0.604 0.396 0.000
J98.2 Interstitial emphysema
0.604 0.396 0.000
N02 Recurrent and persistent haematuria
0.603 0.396 0.000
J84 Other interstitial pulmonary diseases
0.603 0.397 0.000
J43 Emphysema
0.603 0.397 0.000
L05 Pilonidal cyst
0.602 0.398 0.000
L04 Acute lymphadenitis
0.602 0.398 0.000
L01 Impetigo
0.602 0.398 0.000
L00 Staphylococcal scalded skin syndrome
0.602 0.398 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.602 0.398 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.602 0.398 0.000
S27 Injury of other and unspecified intrathoracic organs
0.602 0.398 0.000
T93 Sequelae of injuries of lower limb
0.601 0.399 0.000
D70 Agranulocytosis
0.601 0.399 0.000
N43.3 Hydrocele, unspecified
0.600 0.400 0.000
W00-W19 Falls
0.599 0.401 0.000
M23.3 Other meniscus derangements
0.599 0.401 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.599 0.401 0.000
E66.1 Drug-induced obesity
0.599 0.401 0.000
E66.0 Obesity due to excess calories
0.599 0.401 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.598 0.402 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.598 0.402 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.598 0.402 0.000
M65-M68 Disorders of synovium and tendon
0.597 0.403 0.000
J41 Simple and mucopurulent chronic bronchitis
0.597 0.403 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.597 0.403 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.596 0.404 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.596 0.404 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.596 0.404 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.596 0.404 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.595 0.405 0.000
O97 Death from sequelae of direct obstetric causes
0.595 0.405 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.595 0.405 0.000
O95 Obstetric death of unspecified cause
0.595 0.405 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.595 0.405 0.000
N50.9 Disorder of male genital organs, unspecified
0.595 0.405 0.000
N50.0 Atrophy of testis
0.595 0.405 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.595 0.405 0.000
E29 Testicular dysfunction
0.594 0.406 0.000
K70-K77 Diseases of liver
0.594 0.406 0.000
M14 Arthropathies in other diseases classified elsewhere
0.594 0.406 0.000
M12 Other specific arthropathies
0.594 0.406 0.000
M11 Other crystal arthropathies
0.594 0.406 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.594 0.406 0.000
M08 Juvenile arthritis
0.594 0.406 0.000
M07 Psoriatic and enteropathic arthropathies
0.594 0.406 0.000
A49 Bacterial infection of unspecified site
0.593 0.407 0.000
A48 Other bacterial diseases, not elsewhere classified
0.593 0.407 0.000
A44 Bartonellosis
0.593 0.407 0.000
A43 Nocardiosis
0.593 0.407 0.000
A42 Actinomycosis
0.593 0.407 0.000
A40 Streptococcal septicaemia
0.593 0.407 0.000
A39 Meningococcal infection
0.593 0.407 0.000
A37 Whooping cough
0.593 0.407 0.000
A36 Diphtheria
0.593 0.407 0.000
A32 Listeriosis
0.593 0.407 0.000
A31 Infection due to other mycobacteria
0.593 0.407 0.000
A30 Leprosy [Hansen's disease]
0.593 0.407 0.000
A46 Erysipelas
0.593 0.407 0.000
A38 Scarlet fever
0.593 0.407 0.000
A35 Other tetanus
0.593 0.407 0.000
A34 Obstetrical tetanus
0.593 0.407 0.000
A33 Tetanus neonatorum
0.593 0.407 0.000
S29 Other and unspecified injuries of thorax
0.593 0.407 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.593 0.407 0.000
S26 Injury of heart
0.593 0.407 0.000
S25 Injury of blood vessels of thorax
0.593 0.407 0.000
S24 Injury of nerves and spinal cord at thorax level
0.593 0.407 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.593 0.407 0.000
S21 Open wound of thorax
0.593 0.407 0.000
S20 Superficial injury of thorax
0.593 0.407 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.593 0.407 0.000
D67 Hereditary factor IX deficiency
0.592 0.408 0.000
D66 Hereditary factor VIII deficiency
0.592 0.408 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.592 0.408 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.592 0.408 0.000
N15 Other renal tubulo-interstitial diseases
0.592 0.408 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.592 0.408 0.000
N11 Chronic tubulo-interstitial nephritis
0.592 0.408 0.000
N10 Acute tubulo-interstitial nephritis
0.592 0.408 0.000
O45 Premature separation of placenta [abruptio placentae]
0.592 0.408 0.000
O44 Placenta praevia
0.592 0.408 0.000
O43 Placental disorders
0.592 0.408 0.000
O41 Other disorders of amniotic fluid and membranes
0.592 0.408 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.592 0.408 0.000
O33 Maternal care for known or suspected disproportion
0.592 0.408 0.000
O31 Complications specific to multiple gestation
0.592 0.408 0.000
O30 Multiple gestation
0.592 0.408 0.000
O40 Polyhydramnios
0.592 0.408 0.000
L03.0 Cellulitis of finger and toe
0.592 0.408 0.000
O29 Complications of anaesthesia during pregnancy
0.591 0.408 0.000
O28 Abnormal findings on antenatal screening of mother
0.591 0.408 0.000
O24 Diabetes mellitus in pregnancy
0.591 0.408 0.000
O23 Infections of genito-urinary tract in pregnancy
0.591 0.408 0.000
O22 Venous complications in pregnancy
0.591 0.408 0.000
O21 Excessive vomiting in pregnancy
0.591 0.408 0.000
O25 Malnutrition in pregnancy
0.591 0.408 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.591 0.409 0.000
M15 Polyarthrosis
0.590 0.410 0.000
S22.0 Fracture of thoracic vertebra
0.590 0.410 0.000
O48 Prolonged pregnancy
0.590 0.410 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.588 0.411 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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