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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs148428208
log Bayes Factor = 4.46774
Chromosome 1   position 185,566,551  (GRCh37) Explore rs148428208 on Ensembl!
Variant rs148428208 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I20 Angina pectoris
0.994 0.006 0.000
H25-H28 Disorders of lens
0.986 0.014 0.000
I20.0 Unstable angina
0.977 0.023 0.000
Chapter XXI Factors influencing health status and contact with health services
0.966 0.034 0.000
H40-H42 Glaucoma
0.945 0.055 0.000
H26 Other cataract
0.943 0.057 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.943 0.057 0.000
Chapter X Diseases of the respiratory system
0.943 0.057 0.000
H25 Senile cataract
0.930 0.070 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.928 0.072 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.918 0.082 0.000
I20.9 Angina pectoris, unspecified
0.917 0.083 0.000
J40-J47 Chronic lower respiratory diseases
0.917 0.083 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.912 0.088 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.912 0.088 0.000
H40 Glaucoma
0.907 0.093 0.000
J44 Other chronic obstructive pulmonary disease
0.901 0.099 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.900 0.100 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.894 0.106 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.886 0.114 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.883 0.117 0.000
E70-E90 Metabolic disorders
0.883 0.117 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.882 0.118 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.881 0.119 0.000
H26.9 Cataract, unspecified
0.876 0.124 0.000
I25 Chronic ischaemic heart disease
0.862 0.138 0.000
H25.1 Senile nuclear cataract
0.861 0.139 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.854 0.146 0.000
M20-M25 Other joint disorders
0.846 0.154 0.000
H40.9 Glaucoma, unspecified
0.836 0.164 0.000
H26.8 Other specified cataract
0.833 0.167 0.000
Z72 Problems related to lifestyle
0.832 0.168 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.831 0.169 0.000
I20.8 Other forms of angina pectoris
0.827 0.173 0.000
H30-H36 Disorders of choroid and retina
0.825 0.175 0.000
I30-I52 Other forms of heart disease
0.821 0.179 0.000
I71 Aortic aneurysm and dissection
0.811 0.189 0.000
M23 Internal derangement of knee
0.811 0.189 0.000
Z72.0 Tobacco use
0.809 0.191 0.000
Z60 Problems related to social environment
0.808 0.192 0.000
Chapter VI Diseases of the nervous system
0.808 0.192 0.000
I60-I69 Cerebrovascular diseases
0.802 0.198 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.799 0.201 0.000
Chapter V Mental and behavioural disorders
0.798 0.202 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.797 0.203 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.797 0.203 0.000
M05-M14 Inflammatory polyarthropathies
0.795 0.205 0.000
Chapter VIII Diseases of the ear and mastoid process
0.787 0.213 0.000
Z95.0 Presence of cardiac pacemaker
0.783 0.217 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.777 0.223 0.000
H25.9 Senile cataract, unspecified
0.768 0.232 0.000
I21 Acute myocardial infarction
0.768 0.232 0.000
I24 Other acute ischaemic heart diseases
0.765 0.235 0.000
E78.0 Pure hypercholesterolaemia
0.764 0.236 0.000
M70-M79 Other soft tissue disorders
0.764 0.236 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.762 0.238 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.761 0.238 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.758 0.242 0.000
L20-L30 Dermatitis and eczema
0.754 0.246 0.000
Z60.2 Living alone
0.753 0.247 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.751 0.249 0.000
J47 Bronchiectasis
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.747 0.253 0.000
M23.3 Other meniscus derangements
0.746 0.254 0.000
I05-I09 Chronic rheumatic heart diseases
0.742 0.257 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.742 0.258 0.000
I74 Arterial embolism and thrombosis
0.738 0.262 0.000
I25.1 Atherosclerotic heart disease
0.738 0.262 0.000
I80 Phlebitis and thrombophlebitis
0.735 0.265 0.000
J90-J94 Other diseases of pleura
0.735 0.265 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.734 0.266 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.733 0.267 0.000
H25.8 Other senile cataract
0.733 0.267 0.000
L60-L75 Disorders of skin appendages
0.731 0.269 0.000
Z83 Family history of other specific disorders
0.728 0.272 0.000
H40.1 Primary open-angle glaucoma
0.725 0.275 0.000
L03 Cellulitis
0.724 0.276 0.000
M65-M68 Disorders of synovium and tendon
0.723 0.277 0.000
H40.2 Primary angle-closure glaucoma
0.721 0.279 0.000
H40.0 Glaucoma suspect
0.719 0.281 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.718 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
H55-H59 Other disorders of eye and adnexa
0.715 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.284 0.000
H10-H13 Disorders of conjunctiva
0.715 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.284 0.000
I22 Subsequent myocardial infarction
0.715 0.284 0.000
H35 Other retinal disorders
0.715 0.285 0.000
Z95.1 Presence of aortocoronary bypass graft
0.714 0.286 0.000
I20.1 Angina pectoris with documented spasm
0.713 0.287 0.000
E50-E64 Other nutritional deficiencies
0.712 0.288 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.709 0.291 0.000
E10-E14 Diabetes mellitus
0.707 0.293 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.707 0.293 0.000
H27 Other disorders of lens
0.707 0.293 0.000
I84 Haemorrhoids
0.706 0.294 0.000
M50-M54 Other dorsopathies
0.703 0.297 0.000
L40-L45 Papulosquamous disorders
0.702 0.298 0.000
E78.5 Hyperlipidaemia, unspecified
0.702 0.298 0.000
M13 Other arthritis
0.700 0.300 0.000
Z57 Occupational exposure to risk-factors
0.700 0.300 0.000
Z73 Problems related to life-management difficulty
0.697 0.303 0.000
M80-M85 Disorders of bone density and structure
0.695 0.305 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.694 0.306 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.693 0.306 0.000
E83 Disorders of mineral metabolism
0.693 0.307 0.000
J95-J99 Other diseases of the respiratory system
0.691 0.309 0.000
M45-M49 Spondylopathies
0.689 0.310 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.688 0.312 0.000
I77 Other disorders of arteries and arterioles
0.687 0.313 0.000
J00-J06 Acute upper respiratory infections
0.686 0.314 0.000
E20-E35 Disorders of other endocrine glands
0.685 0.315 0.000
Z94 Transplanted organ and tissue status
0.685 0.315 0.000
I83 Varicose veins of lower extremities
0.685 0.315 0.000
J43 Emphysema
0.683 0.317 0.000
Z75 Problems related to medical facilities and other health care
0.681 0.318 0.000
Z93 Artificial opening status
0.681 0.319 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.679 0.321 0.000
J60-J70 Lung diseases due to external agents
0.678 0.322 0.000
H42 Glaucoma in diseases classified elsewhere
0.678 0.322 0.000
H53-H54 Visual disturbances and blindness
0.677 0.323 0.000
H26.3 Drug-induced cataract
0.676 0.324 0.000
H26.2 Complicated cataract
0.676 0.324 0.000
H26.1 Traumatic cataract
0.676 0.324 0.000
H26.0 Infantile, juvenile and presenile cataract
0.676 0.324 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.324 0.000
M91-M94 Chondropathies
0.676 0.324 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
M60-M63 Disorders of muscles
0.676 0.324 0.000
M00-M03 Infectious arthropathies
0.676 0.324 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.676 0.324 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.676 0.324 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.676 0.324 0.000
E86 Volume depletion
0.676 0.324 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.675 0.325 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.675 0.325 0.000
M31 Other necrotising vasculopathies
0.672 0.328 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.670 0.330 0.000
Z99.3 Dependence on wheelchair
0.669 0.331 0.000
H25.2 Senile cataract, morgagnian type
0.667 0.333 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.667 0.333 0.000
L50-L54 Urticaria and erythema
0.666 0.334 0.000
E40-E46 Malnutrition
0.665 0.335 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.665 0.335 0.000
Z95.4 Presence of other heart-valve replacement
0.663 0.337 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.661 0.339 0.000
M40-M43 Deforming dorsopathies
0.661 0.339 0.000
I46 Cardiac arrest
0.658 0.342 0.000
L10-L14 Bullous disorders
0.658 0.342 0.000
J41 Simple and mucopurulent chronic bronchitis
0.657 0.343 0.000
J46 Status asthmaticus
0.657 0.343 0.000
J42 Unspecified chronic bronchitis
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.657 0.343 0.000
I21.4 Acute subendocardial myocardial infarction
0.657 0.343 0.000
J09-J18 Influenza and pneumonia
0.654 0.345 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.654 0.346 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.654 0.346 0.000
I78 Diseases of capillaries
0.654 0.346 0.000
I72 Other aneurysm
0.654 0.346 0.000
I70 Atherosclerosis
0.654 0.346 0.000
Z97 Presence of other devices
0.654 0.346 0.000
Z89 Acquired absence of limb
0.654 0.346 0.000
Z84 Family history of other conditions
0.654 0.346 0.000
Z81 Family history of mental and behavioural disorders
0.654 0.346 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.653 0.347 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.652 0.348 0.000
H26.4 After-cataract
0.651 0.349 0.000
H40.8 Other glaucoma
0.650 0.349 0.000
H40.6 Glaucoma secondary to drugs
0.650 0.349 0.000
H40.5 Glaucoma secondary to other eye disorders
0.650 0.349 0.000
H40.4 Glaucoma secondary to eye inflammation
0.650 0.349 0.000
H40.3 Glaucoma secondary to eye trauma
0.650 0.349 0.000
I69 Sequelae of cerebrovascular disease
0.651 0.349 0.000
I51 Complications and ill-defined descriptions of heart disease
0.647 0.353 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.647 0.353 0.000
M79.8 Other specified soft tissue disorders
0.646 0.354 0.000
J40 Bronchitis, not specified as acute or chronic
0.646 0.354 0.000
Z76 Persons encountering health services in other circumstances
0.645 0.354 0.000
Z74 Problems related to care-provider dependency
0.645 0.354 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.645 0.354 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.645 0.354 0.000
I63 Cerebral infarction
0.645 0.354 0.000
E10 Insulin-dependent diabetes mellitus
0.645 0.355 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.641 0.359 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.641 0.359 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.641 0.359 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.641 0.359 0.000
Z82.2 Family history of deafness and hearing loss
0.641 0.359 0.000
Z82.1 Family history of blindness and visual loss
0.641 0.359 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.641 0.359 0.000
H65-H75 Diseases of middle ear and mastoid
0.640 0.360 0.000
G40-G47 Episodic and paroxysmal disorders
0.638 0.361 0.000
I73 Other peripheral vascular diseases
0.638 0.362 0.000
M23.8 Other internal derangements of knee
0.636 0.363 0.000
Z65 Problems related to other psychosocial circumstances
0.635 0.365 0.000
Z64 Problems related to certain psychosocial circumstances
0.635 0.365 0.000
Z63 Other problems related to primary support group, including family circumstances
0.635 0.365 0.000
Z62 Other problems related to upbringing
0.635 0.365 0.000
Z61 Problems related to negative life events in childhood
0.635 0.365 0.000
Z59 Problems related to housing and economic circumstances
0.635 0.365 0.000
Z58 Problems related to physical environment
0.635 0.365 0.000
Z56 Problems related to employment and unemployment
0.635 0.365 0.000
Z55 Problems related to education and literacy
0.635 0.365 0.000
I45 Other conduction disorders
0.635 0.365 0.000
Z80 Family history of malignant neoplasm
0.635 0.365 0.000
E00-E07 Disorders of thyroid gland
0.634 0.366 0.000
I47 Paroxysmal tachycardia
0.634 0.366 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.633 0.367 0.000
I88 Nonspecific lymphadenitis
0.633 0.367 0.000
I87 Other disorders of veins
0.633 0.367 0.000
I86 Varicose veins of other sites
0.633 0.367 0.000
I85 Oesophageal varices
0.633 0.367 0.000
I82 Other venous embolism and thrombosis
0.633 0.367 0.000
I81 Portal vein thrombosis
0.633 0.367 0.000
E88 Other metabolic disorders
0.633 0.367 0.000
E85 Amyloidosis
0.633 0.367 0.000
E84 Cystic fibrosis
0.633 0.367 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.633 0.367 0.000
E79 Disorders of purine and pyrimidine metabolism
0.633 0.367 0.000
E77 Disorders of glycoprotein metabolism
0.633 0.367 0.000
E76 Disorders of glycosaminoglycan metabolism
0.633 0.367 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.633 0.367 0.000
E74 Other disorders of carbohydrate metabolism
0.633 0.367 0.000
E73 Lactose intolerance
0.633 0.367 0.000
E72 Other disorders of amino-acid metabolism
0.633 0.367 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.633 0.367 0.000
E70 Disorders of aromatic amino-acid metabolism
0.633 0.367 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.633 0.367 0.000
M13.9 Arthritis, unspecified
0.632 0.368 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.632 0.368 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.632 0.368 0.000
Z95.3 Presence of xenogenic heart valve
0.632 0.368 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.629 0.371 0.000
I21.9 Acute myocardial infarction, unspecified
0.628 0.372 0.000
L03.1 Cellulitis of other parts of limb
0.627 0.373 0.000
M79.6 Pain in limb
0.627 0.373 0.000
I84.8 Unspecified haemorrhoids with other complications
0.626 0.374 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.625 0.375 0.000
I44 Atrioventricular and left bundle-branch block
0.623 0.377 0.000
Z86 Personal history of certain other diseases
0.622 0.378 0.000
H35.8 Other specified retinal disorders
0.622 0.378 0.000
I49 Other cardiac arrhythmias
0.619 0.381 0.000
H34 Retinal vascular occlusions
0.618 0.382 0.000
I25.6 Silent myocardial ischaemia
0.618 0.382 0.000
I25.5 Ischaemic cardiomyopathy
0.618 0.382 0.000
I25.4 Coronary artery aneurysm
0.618 0.382 0.000
I25.3 Aneurysm of heart
0.618 0.382 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.618 0.382 0.000
Z82.3 Family history of stroke
0.617 0.383 0.000
I25.2 Old myocardial infarction
0.616 0.384 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.614 0.386 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.612 0.388 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.612 0.388 0.000
L03.8 Cellulitis of other sites
0.612 0.388 0.000
I31 Other diseases of pericardium
0.611 0.389 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.607 0.393 0.000
J30-J39 Other diseases of upper respiratory tract
0.607 0.393 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.606 0.394 0.000
M34 Systemic sclerosis
0.606 0.394 0.000
M33 Dermatopolymyositis
0.606 0.394 0.000
M32 Systemic lupus erythematosus
0.606 0.394 0.000
M30 Polyarteritis nodosa and related conditions
0.606 0.394 0.000
M24 Other specific joint derangements
0.606 0.394 0.000
M22 Disorders of patella
0.606 0.394 0.000
M21 Other acquired deformities of limbs
0.606 0.394 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.605 0.395 0.000
L30 Other dermatitis
0.605 0.395 0.000
M07 Psoriatic and enteropathic arthropathies
0.604 0.396 0.000
Z85 Personal history of malignant neoplasm
0.603 0.397 0.000
H25.0 Senile incipient cataract
0.603 0.397 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.602 0.398 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.601 0.398 0.000
M35 Other systemic involvement of connective tissue
0.601 0.399 0.000
E10.9 Without complications
0.601 0.399 0.000
I24.8 Other forms of acute ischaemic heart disease
0.597 0.403 0.000
Z72.9 Problem related to lifestyle, unspecified
0.596 0.404 0.000
Z72.8 Other problems related to lifestyle
0.596 0.404 0.000
Z72.6 Gambling and betting
0.596 0.404 0.000
Z72.5 High-risk sexual behaviour
0.596 0.404 0.000
Z72.4 Inappropriate diet and eating habits
0.596 0.404 0.000
Z72.3 Lack of physical exercise
0.596 0.404 0.000
Z72.2 Drug use
0.596 0.404 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.596 0.404 0.000
E78.8 Other disorders of lipoprotein metabolism
0.596 0.404 0.000
E78.6 Lipoprotein deficiency
0.596 0.404 0.000
E78.4 Other hyperlipidaemia
0.596 0.404 0.000
E78.3 Hyperchylomicronaemia
0.596 0.404 0.000
E78.2 Mixed hyperlipidaemia
0.596 0.404 0.000
E78.1 Pure hyperglyceridaemia
0.596 0.404 0.000
I95 Hypotension
0.592 0.408 0.000
F30-F39 Mood [affective] disorders
0.592 0.408 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.591 0.409 0.000
H31 Other disorders of choroid
0.591 0.409 0.000
H30 Chorioretinal inflammation
0.591 0.409 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.591 0.409 0.000
I52 Other heart disorders in diseases classified elsewhere
0.589 0.411 0.000
I48 Atrial fibrillation and flutter
0.589 0.411 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.589 0.411 0.000
I41 Myocarditis in diseases classified elsewhere
0.589 0.411 0.000
I40 Acute myocarditis
0.589 0.411 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.589 0.411 0.000
I37 Pulmonary valve disorders
0.589 0.411 0.000
I36 Nonrheumatic tricuspid valve disorders
0.589 0.411 0.000
I33 Acute and subacute endocarditis
0.589 0.411 0.000
I32 Pericarditis in diseases classified elsewhere
0.589 0.411 0.000
I30 Acute pericarditis
0.589 0.411 0.000
I38 Endocarditis, valve unspecified
0.589 0.411 0.000
H60-H62 Diseases of external ear
0.587 0.413 0.000
S80-S89 Injuries to the knee and lower leg
0.586 0.413 0.000
J92 Pleural plaque
0.586 0.414 0.000
G90-G99 Other disorders of the nervous system
0.586 0.414 0.000
L29 Pruritus
0.586 0.414 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.585 0.415 0.000
E89.0 Postprocedural hypothyroidism
0.585 0.415 0.000
I84.1 Internal haemorrhoids with other complications
0.585 0.415 0.000
Z83.7 Family history of diseases of the digestive system
0.584 0.416 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.581 0.418 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.581 0.418 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.581 0.418 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.581 0.418 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.581 0.418 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.581 0.418 0.000
I71.0 Dissection of aorta [any part]
0.581 0.418 0.000
M23.9 Internal derangement of knee, unspecified
0.581 0.419 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.581 0.419 0.000
M23.5 Chronic instability of knee
0.581 0.419 0.000
M23.4 Loose body in knee
0.581 0.419 0.000
M23.1 Discoid meniscus (congenital)
0.581 0.419 0.000
M23.0 Cystic meniscus
0.581 0.419 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.581 0.419 0.000
Z60.9 Problem related to social environment, unspecified
0.580 0.420 0.000
Z60.8 Other problems related to social environment
0.580 0.420 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.580 0.420 0.000
Z60.4 Social exclusion and rejection
0.580 0.420 0.000
Z60.3 Acculturation difficulty
0.580 0.420 0.000
Z60.1 Atypical parenting situation
0.580 0.420 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.580 0.420 0.000
E55 Vitamin D deficiency
0.579 0.421 0.000
G70-G73 Diseases of myoneural junction and muscle
0.579 0.421 0.000
G30-G32 Other degenerative diseases of the nervous system
0.579 0.421 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.579 0.421 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.579 0.421 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.579 0.421 0.000
I42 Cardiomyopathy
0.579 0.421 0.000
Z99.2 Dependence on renal dialysis
0.579 0.421 0.000
M50 Cervical disk disorders
0.578 0.422 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.578 0.422 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.577 0.423 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.575 0.425 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.575 0.425 0.000
I62 Other nontraumatic intracranial haemorrhage
0.575 0.425 0.000
I61 Intracerebral haemorrhage
0.575 0.425 0.000
I60 Subarachnoid haemorrhage
0.575 0.425 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.573 0.427 0.000
Z96 Presence of other functional implants
0.573 0.427 0.000
F99-F99 Unspecified mental disorder
0.572 0.427 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.572 0.427 0.000
F80-F89 Disorders of psychological development
0.572 0.427 0.000
F70-F79 Mental retardation
0.572 0.427 0.000
F60-F69 Disorders of adult personality and behaviour
0.572 0.427 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.572 0.427 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.572 0.427 0.000
D80-D89 Certain disorders involving the immune mechanism
0.572 0.428 0.000
D55-D59 Haemolytic anaemias
0.572 0.428 0.000
L05 Pilonidal cyst
0.572 0.428 0.000
L04 Acute lymphadenitis
0.572 0.428 0.000
L01 Impetigo
0.572 0.428 0.000
L00 Staphylococcal scalded skin syndrome
0.572 0.428 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.571 0.429 0.000
H43 Disorders of vitreous body
0.571 0.429 0.000
M14 Arthropathies in other diseases classified elsewhere
0.570 0.430 0.000
M12 Other specific arthropathies
0.570 0.430 0.000
M11 Other crystal arthropathies
0.570 0.430 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.570 0.430 0.000
M08 Juvenile arthritis
0.570 0.430 0.000
M05 Seropositive rheumatoid arthritis
0.570 0.430 0.000
H33 Retinal detachments and breaks
0.570 0.430 0.000
Chapter XX External causes of morbidity and mortality
0.569 0.431 0.000
Z86.7 Personal history of diseases of the circulatory system
0.568 0.432 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.568 0.432 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.566 0.434 0.000
Z57.2 Occupational exposure to dust
0.566 0.434 0.000
J93 Pneumothorax
0.562 0.437 0.000
H50 Other strabismus
0.559 0.440 0.000
I35 Nonrheumatic aortic valve disorders
0.558 0.441 0.000
I08 Multiple valve diseases
0.558 0.442 0.000
D61 Other aplastic anaemias
0.557 0.443 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.557 0.443 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.557 0.443 0.000
Z99.8 Dependence on other enabling machines and devices
0.557 0.443 0.000
Z99.4 Dependence on artificial heart
0.557 0.443 0.000
Z99.1 Dependence on respirator
0.557 0.443 0.000
Z99.0 Dependence on aspirator
0.557 0.443 0.000
L08 Other local infections of skin and subcutaneous tissue
0.557 0.443 0.000
G35 Multiple sclerosis
0.556 0.443 0.000
H90-H95 Other disorders of ear
0.555 0.445 0.000
M10 Gout
0.555 0.445 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.554 0.446 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.552 0.448 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.552 0.448 0.000
H36 Retinal disorders in diseases classified elsewhere
0.551 0.448 0.000
I46.9 Cardiac arrest, unspecified
0.551 0.449 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.550 0.449 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.550 0.449 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.550 0.449 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.549 0.451 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.548 0.452 0.000
I24.1 Dressler's syndrome
0.548 0.452 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.548 0.452 0.000
M31.6 Other giant cell arteritis
0.548 0.452 0.000
M77 Other enthesopathies
0.548 0.452 0.000
M76 Enthesopathies of lower limb, excluding foot
0.548 0.452 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.548 0.452 0.000
M71 Other bursopathies
0.548 0.452 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.548 0.452 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.547 0.453 0.000
Z95.2 Presence of prosthetic heart valve
0.547 0.453 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.547 0.453 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.547 0.453 0.000
I99 Other and unspecified disorders of circulatory system
0.547 0.453 0.000
E83.5 Disorders of calcium metabolism
0.546 0.454 0.000
L40 Psoriasis
0.546 0.454 0.000
H35.3 Degeneration of macula and posterior pole
0.546 0.454 0.000
S50-S59 Injuries to the elbow and forearm
0.545 0.455 0.000
M65 Synovitis and tenosynovitis
0.545 0.455 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.545 0.455 0.000
Z98 Other postsurgical states
0.543 0.456 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.544 0.456 0.000
Q80-Q89 Other congenital malformations
0.544 0.456 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.544 0.456 0.000
Q60-Q64 Congenital malformations of the urinary system
0.544 0.456 0.000
Q50-Q56 Congenital malformations of genital organs
0.544 0.456 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.544 0.456 0.000
Q35-Q37 Cleft lip and cleft palate
0.544 0.456 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.544 0.456 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.544 0.456 0.000
Q00-Q07 Congenital malformations of the nervous system
0.544 0.456 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.543 0.457 0.000
H52 Disorders of refraction and accommodation
0.543 0.457 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.543 0.457 0.000
O00-O08 Pregnancy with abortive outcome
0.543 0.457 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.542 0.458 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.542 0.458 0.000
M67 Other disorders of synovium and tendon
0.542 0.458 0.000
L28 Lichen simplex chronicus and prurigo
0.540 0.459 0.000
L27 Dermatitis due to substances taken internally
0.540 0.459 0.000
L25 Unspecified contact dermatitis
0.540 0.459 0.000
L24 Irritant contact dermatitis
0.540 0.459 0.000
L23 Allergic contact dermatitis
0.540 0.459 0.000
L21 Seborrhoeic dermatitis
0.540 0.459 0.000
L20 Atopic dermatitis
0.540 0.459 0.000
L26 Exfoliative dermatitis
0.540 0.459 0.000
L22 Diaper [napkin] dermatitis
0.540 0.459 0.000
G81 Hemiplegia
0.540 0.460 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.539 0.461 0.000
Z83.5 Family history of eye and ear disorders
0.539 0.461 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.539 0.461 0.000
T79-T79 Certain early complications of trauma
0.539 0.461 0.000
T66-T78 Other and unspecified effects of external causes
0.539 0.461 0.000
T33-T35 Frostbite
0.539 0.461 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.539 0.461 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.539 0.461 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.539 0.461 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.539 0.461 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.539 0.461 0.000
T00-T07 Injuries involving multiple body regions
0.539 0.461 0.000
S90-S99 Injuries to the ankle and foot
0.539 0.461 0.000
S10-S19 Injuries to the neck
0.539 0.461 0.000
H80-H83 Diseases of inner ear
0.538 0.461 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.538 0.462 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.537 0.463 0.000
H44 Disorders of globe
0.537 0.463 0.000
M13.98 Arthritis, unspecified (Other)
0.537 0.463 0.000
I34 Nonrheumatic mitral valve disorders
0.537 0.463 0.000
H51 Other disorders of binocular movement
0.535 0.465 0.000
H49 Paralytic strabismus
0.535 0.465 0.000
H72 Perforation of tympanic membrane
0.535 0.465 0.000
Chapter XIV Diseases of the genitourinary system
0.535 0.465 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.535 0.465 0.000
M23.37 Other meniscus derangements-Capsular lig
0.535 0.465 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.535 0.465 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.535 0.465 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.535 0.465 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.535 0.465 0.000
Z93.3 Colostomy status
0.534 0.465 0.000
I63.9 Cerebral infarction, unspecified
0.533 0.467 0.000
G47 Sleep disorders
0.533 0.467 0.000
I09 Other rheumatic heart diseases
0.532 0.467 0.000
I07 Rheumatic tricuspid valve diseases
0.532 0.467 0.000
I06 Rheumatic aortic valve diseases
0.532 0.467 0.000
I05 Rheumatic mitral valve diseases
0.532 0.467 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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