TreeWAS – Variant ID: rs148743497

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.999	0.001
E70-E90 Metabolic disorders	0.998	0.002
N17-N19 Renal failure	0.998	0.002
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.996	0.004
N17 Acute renal failure	0.995	0.005
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.994	0.006
Chapter VII Diseases of the eye and adnexa	0.994	0.006
E87 Other disorders of fluid, electrolyte and acid-base balance	0.994	0.006
I20-I25 Ischaemic heart diseases	0.993	0.007
Chapter XXI Factors influencing health status and contact with health services	0.993	0.007
N17.9 Acute renal failure, unspecified	0.993	0.007
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.992	0.008
I30-I52 Other forms of heart disease	0.992	0.008
I70-I79 Diseases of arteries, arterioles and capillaries	0.991	0.009
Y83.1 Surgical operation with implant of artificial internal device	0.990	0.010
Chapter I Certain infectious and parasitic diseases	0.989	0.011
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.985	0.015
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.984	0.016
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.981	0.019
Z92 Personal history of medical treatment	0.976	0.024
J44 Other chronic obstructive pulmonary disease	0.976	0.024
Chapter XII Diseases of the skin and subcutaneous tissue	0.974	0.026
Z40-Z54 Persons encountering health services for specific procedures and health care	0.972	0.028
J09-J18 Influenza and pneumonia	0.971	0.029
I44 Atrioventricular and left bundle-branch block	0.969	0.031
H30-H36 Disorders of choroid and retina	0.964	0.036
C79 Secondary malignant neoplasm of other sites	0.964	0.036
J43 Emphysema	0.963	0.037
I73 Other peripheral vascular diseases	0.959	0.041
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.958	0.042
S00-S09 Injuries to the head	0.957	0.043
C78.7 Secondary malignant neoplasm of liver	0.956	0.044
J80-J84 Other respiratory diseases principally affecting the interstitium	0.955	0.045
N30-N39 Other diseases of urinary system	0.952	0.048
J18 Pneumonia, organism unspecified	0.952	0.048
I24 Other acute ischaemic heart diseases	0.949	0.051
Z92.3 Personal history of irradiation	0.949	0.051
Z51 Other medical care	0.949	0.051
Z98 Other postsurgical states	0.944	0.056
E87.5 Hyperkalaemia	0.943	0.057
T85 Complications of other internal prosthetic devices, implants and grafts	0.941	0.059
S70-S79 Injuries to the hip and thigh	0.941	0.059
I10-I15 Hypertensive diseases	0.939	0.061
J43.9 Emphysema, unspecified	0.939	0.061
I44.0 Atrioventricular block, first degree	0.937	0.063
N18 Chronic renal failure	0.934	0.066
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.934	0.066
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.931	0.069
L00-L08 Infections of the skin and subcutaneous tissue	0.929	0.071
Z92.6 Personal history of chemotherapy for neoplastic disease	0.927	0.073
C15-C26 Malignant neoplasms of digestive organs	0.924	0.076
A00-A09 Intestinal infectious diseases	0.923	0.077
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.922	0.078
I50 Heart failure	0.916	0.084
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.915	0.085
Z93 Artificial opening status	0.914	0.086
Z45 Adjustment and management of implanted device	0.914	0.086
H35 Other retinal disorders	0.913	0.087
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.911	0.089
J18.1 Lobar pneumonia, unspecified	0.911	0.089
E87.1 Hypo-osmolality and hyponatraemia	0.907	0.093
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.905	0.095
J20-J22 Other acute lower respiratory infections	0.903	0.097
D37-D48 Neoplasms of uncertain or unknown behaviour	0.903	0.097
M80-M85 Disorders of bone density and structure	0.899	0.101
I25 Chronic ischaemic heart disease	0.898	0.102
C18 Malignant neoplasm of colon	0.898	0.102
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.897	0.103
L03 Cellulitis	0.896	0.104
E83 Disorders of mineral metabolism	0.895	0.105
L80-L99 Other disorders of the skin and subcutaneous tissue	0.893	0.107
I73.9 Peripheral vascular disease, unspecified	0.892	0.108
Z98.0 Intestinal bypass and anastomosis status	0.892	0.108
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.891	0.109
Z43 Attention to artificial openings	0.889	0.111
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.888	0.112
I20 Angina pectoris	0.887	0.113
I44.2 Atrioventricular block, complete	0.884	0.116
C77.3 Axillary and upper limb lymph nodes	0.883	0.117
I22 Subsequent myocardial infarction	0.883	0.117
Y43 Primarily systemic agents	0.881	0.119
I77 Other disorders of arteries and arterioles	0.879	0.121
M20-M25 Other joint disorders	0.879	0.121
A30-A49 Other bacterial diseases	0.875	0.125
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.871	0.129
S80-S89 Injuries to the knee and lower leg	0.871	0.129
Z94 Transplanted organ and tissue status	0.871	0.129
E00-E07 Disorders of thyroid gland	0.869	0.131
J47 Bronchiectasis	0.869	0.131
C78.0 Secondary malignant neoplasm of lung	0.868	0.132
I20.9 Angina pectoris, unspecified	0.866	0.134
I73.0 Raynaud's syndrome	0.864	0.136
S01 Open wound of head	0.863	0.137
H25-H28 Disorders of lens	0.860	0.140
A09.9 Gastroenteritis and colitis of unspecified origin	0.860	0.140
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.859	0.141
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.858	0.142
L03.1 Cellulitis of other parts of limb	0.858	0.142
M86-M90 Other osteopathies	0.857	0.143
H35.8 Other specified retinal disorders	0.855	0.145
E50-E64 Other nutritional deficiencies	0.855	0.145
M05-M14 Inflammatory polyarthropathies	0.853	0.147
Y83.8 Other surgical procedures	0.853	0.147
I25.9 Chronic ischaemic heart disease, unspecified	0.853	0.147
N31.8 Other neuromuscular dysfunction of bladder	0.851	0.149
I12 Hypertensive renal disease	0.851	0.149
E88 Other metabolic disorders	0.848	0.152
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.848	0.152
I50.0 Congestive heart failure	0.846	0.154
I24.9 Acute ischaemic heart disease, unspecified	0.844	0.156
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.844	0.156
R50-R69 General symptoms and signs	0.843	0.157
I24.8 Other forms of acute ischaemic heart disease	0.842	0.158
N25-N29 Other disorders of kidney and ureter	0.841	0.159
E87.2 Acidosis	0.840	0.160
J84 Other interstitial pulmonary diseases	0.839	0.161
Y83.0 Surgical operation with transplant of whole organ	0.839	0.161
I05-I09 Chronic rheumatic heart diseases	0.838	0.162
E86 Volume depletion	0.838	0.162
S72 Fracture of femur	0.837	0.163
J60-J70 Lung diseases due to external agents	0.836	0.164
J90-J94 Other diseases of pleura	0.835	0.165
T81 Complications of procedures, not elsewhere classified	0.834	0.166
N18.9 Chronic renal failure, unspecified	0.833	0.167
N70-N77 Inflammatory diseases of female pelvic organs	0.831	0.169
S60-S69 Injuries to the wrist and hand	0.830	0.170
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.829	0.171
N35 Urethral stricture	0.829	0.171
J18.9 Pneumonia, unspecified	0.828	0.172
B15-B19 Viral hepatitis	0.828	0.172
Y43.3 Other antineoplastic drugs	0.825	0.175
Z51.9 Medical care, unspecified	0.825	0.175
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.824	0.176
E20-E35 Disorders of other endocrine glands	0.822	0.178
J80 Adult respiratory distress syndrome	0.822	0.178
H43-H45 Disorders of vitreous body and globe	0.820	0.180
B35-B49 Mycoses	0.819	0.181
I71 Aortic aneurysm and dissection	0.819	0.181
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.818	0.181
Z45.2 Adjustment and management of vascular access device	0.818	0.182
C18.2 Ascending colon	0.817	0.183
M10 Gout	0.816	0.184
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.816	0.184
Z93.1 Gastrostomy status	0.815	0.185
J22 Unspecified acute lower respiratory infection	0.815	0.185
E10-E14 Diabetes mellitus	0.815	0.185
E87.3 Alkalosis	0.813	0.187
C79.2 Secondary malignant neoplasm of skin	0.812	0.188
M50-M54 Other dorsopathies	0.812	0.188
H25 Senile cataract	0.811	0.189
C50-C50 Malignant neoplasm of breast	0.810	0.189
N19 Unspecified renal failure	0.810	0.190
M81 Osteoporosis without pathological fracture	0.810	0.190
Z98.1 Arthrodesis status	0.809	0.191
I10 Essential (primary) hypertension	0.809	0.191
T84.0 Mechanical complication of internal joint prosthesis	0.808	0.192
T86 Failure and rejection of transplanted organs and tissues	0.807	0.193
Z51.5 Palliative care	0.807	0.193
S00 Superficial injury of head	0.807	0.193
Z47 Other orthopaedic follow-up care	0.806	0.194
T85.4 Mechanical complication of breast prosthesis and implant	0.805	0.195
J44.8 Other specified chronic obstructive pulmonary disease	0.805	0.195
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.802	0.198
R63 Symptoms and signs concerning food and fluid intake	0.802	0.198
J81 Pulmonary oedema	0.800	0.200
H36 Retinal disorders in diseases classified elsewhere	0.796	0.204
C18.7 Sigmoid colon	0.796	0.204
Z51.3 Blood transfusion without reported diagnosis	0.796	0.204
Y51 Drugs primarily affecting the autonomic nervous system	0.795	0.205
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.794	0.206
I77.1 Stricture of artery	0.794	0.206
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.793	0.207
I50.9 Heart failure, unspecified	0.792	0.208
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.791	0.209
Z92.4 Personal history of major surgery, not elsewhere classified	0.791	0.209
I74 Arterial embolism and thrombosis	0.790	0.210
M10.9 Gout, unspecified	0.790	0.210
M70-M79 Other soft tissue disorders	0.789	0.211
J95-J99 Other diseases of the respiratory system	0.788	0.212
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.788	0.212
Z95 Presence of cardiac and vascular implants and grafts	0.788	0.212
R53 Malaise and fatigue	0.788	0.212
Chapter VIII Diseases of the ear and mastoid process	0.787	0.213
T66-T78 Other and unspecified effects of external causes	0.787	0.213
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.787	0.213
S50-S59 Injuries to the elbow and forearm	0.786	0.214
Z92.1 Personal history of long-term (current) use of anticoagulants	0.784	0.216
H10-H13 Disorders of conjunctiva	0.783	0.217
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.783	0.217
S79 Other and unspecified injuries of hip and thigh	0.782	0.218
B25-B34 Other viral diseases	0.782	0.218
Z94.0 Kidney transplant status	0.781	0.219
Z51.0 Radiotherapy session	0.780	0.220
L97 Ulcer of lower limb, not elsewhere classified	0.780	0.220
I22.9 Subsequent myocardial infarction of unspecified site	0.779	0.221
I51 Complications and ill-defined descriptions of heart disease	0.779	0.221
A41 Other septicaemia	0.779	0.221
S06 Intracranial injury	0.778	0.222
E87.0 Hyperosmolality and hypernatraemia	0.778	0.222
D70-D77 Other diseases of blood and blood-forming organs	0.778	0.222
H33 Retinal detachments and breaks	0.778	0.222
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.778	0.222
R00 Abnormalities of heart beat	0.777	0.223
H25.8 Other senile cataract	0.776	0.224
Y84.2 Radiological procedure and radiotherapy	0.776	0.224
D00-D09 In situ neoplasms	0.775	0.225
Y83.2 Surgical operation with anastomosis, bypass or graft	0.775	0.225
M25 Other joint disorders, not elsewhere classified	0.774	0.226
S01.8 Open wound of other parts of head	0.774	0.226
E87.6 Hypokalaemia	0.772	0.228
I35 Nonrheumatic aortic valve disorders	0.771	0.228
Z45.8 Adjustment and management of other implanted devices	0.771	0.229
C60-C63 Malignant neoplasms of male genital organs	0.771	0.229
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.769	0.230
Z51.1 Chemotherapy session for neoplasm	0.769	0.231
Z43.6 Attention to other artificial openings of urinary tract	0.769	0.231
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.769	0.231
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.769	0.231
N00-N08 Glomerular diseases	0.769	0.231
H53-H54 Visual disturbances and blindness	0.766	0.233
I12.0 Hypertensive renal disease with renal failure	0.765	0.235
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.764	0.236
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.762	0.238
S70 Superficial injury of hip and thigh	0.762	0.238
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.761	0.239
M10.99 Gout, unspecified (Site unspecified)	0.761	0.239
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.761	0.239
M54 Dorsalgia	0.761	0.239
R00.2 Palpitations	0.760	0.240
J18.0 Bronchopneumonia, unspecified	0.760	0.240
C71 Malignant neoplasm of brain	0.758	0.242
Y83.4 Other reconstructive surgery	0.758	0.242
E83.5 Disorders of calcium metabolism	0.757	0.243
L02 Cutaneous abscess, furuncle and carbuncle	0.757	0.243
I45 Other conduction disorders	0.757	0.243
J00-J06 Acute upper respiratory infections	0.756	0.244
R63.4 Abnormal weight loss	0.755	0.245
M60-M63 Disorders of muscles	0.755	0.245
I46 Cardiac arrest	0.751	0.249
T88 Other complications of surgical and medical care, not elsewhere classified	0.751	0.249
S40-S49 Injuries to the shoulder and upper arm	0.751	0.249
M91-M94 Chondropathies	0.751	0.249
J84.1 Other interstitial pulmonary diseases with fibrosis	0.749	0.251
S20-S29 Injuries to the thorax	0.749	0.251
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.748	0.252
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.747	0.253
H35.3 Degeneration of macula and posterior pole	0.747	0.253
C18.4 Transverse colon	0.747	0.253
T85.2 Mechanical complication of intraocular lens	0.746	0.253
N36 Other disorders of urethra	0.746	0.254
X60-X84 Intentional self-harm	0.746	0.254
M81.9 Osteoporosis, unspecified	0.746	0.254
M35 Other systemic involvement of connective tissue	0.745	0.255
S02 Fracture of skull and facial bones	0.744	0.256
Chapter XXII Codes for special purposes	0.743	0.257
Z43.3 Attention to colostomy	0.743	0.257
I38 Endocarditis, valve unspecified	0.741	0.258
N35.9 Urethral stricture, unspecified	0.741	0.259
C79.8 Secondary malignant neoplasm of other specified sites	0.741	0.259
Z93.4 Other artificial openings of gastro-intestinal tract status	0.741	0.259
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.741	0.259
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.741	0.259
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.740	0.260
N18.4 Chronic kidney disease, stage 4	0.740	0.260
D80-D89 Certain disorders involving the immune mechanism	0.740	0.260
N99-N99 Other disorders of the genitourinary system	0.739	0.261
I72 Other aneurysm	0.739	0.261
L82 Seborrhoeic keratosis	0.739	0.261
Z51.2 Other chemotherapy	0.739	0.261
Z93.5 Cystostomy status	0.738	0.262
L03.0 Cellulitis of finger and toe	0.738	0.262
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.738	0.262
M54.9 Dorsalgia, unspecified	0.737	0.263
I95-I99 Other and unspecified disorders of the circulatory system	0.737	0.263
L50-L54 Urticaria and erythema	0.737	0.263
C64-C68 Malignant neoplasms of urinary tract	0.736	0.264
C78.2 Secondary malignant neoplasm of pleura	0.736	0.264
E87.7 Fluid overload	0.735	0.265
J44.9 Chronic obstructive pulmonary disease, unspecified	0.735	0.265
D60-D64 Aplastic and other anaemias	0.735	0.265
I42 Cardiomyopathy	0.735	0.265
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.735	0.265
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.734	0.266
M84 Disorders of continuity of bone	0.733	0.266
Y60-Y69 Misadventures to patients during surgical and medical care	0.733	0.267
Z49 Care involving dialysis	0.733	0.267
H55-H59 Other disorders of eye and adnexa	0.732	0.267
L89 Decubitus ulcer	0.732	0.268
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.732	0.268
D45 Polycythaemia vera	0.730	0.270
E55 Vitamin D deficiency	0.729	0.271
N28 Other disorders of kidney and ureter, not elsewhere classified	0.728	0.272
Z96 Presence of other functional implants	0.725	0.275
N18.0 End-stage renal disease	0.724	0.276
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.724	0.276
M79 Other soft tissue disorders, not elsewhere classified	0.723	0.277
Z92.0 Personal history of contraception	0.723	0.277
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.723	0.277
J42 Unspecified chronic bronchitis	0.722	0.278
W20-W49 Exposure to inanimate mechanical forces	0.721	0.279
E83.3 Disorders of phosphorus metabolism	0.721	0.279
J69 Pneumonitis due to solids and liquids	0.718	0.281
H40-H42 Glaucoma	0.718	0.281
R50 Fever of unknown origin	0.718	0.282
E83.1 Disorders of iron metabolism	0.717	0.283
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.717	0.283
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
Y00-Y09 Assault	0.717	0.283
X85-X99 Assault	0.717	0.283
X58-X59 Accidental exposure to other and unspecified factors	0.717	0.283
X50-X57 Overexertion, travel and privation	0.717	0.283
X40-X49 Accidental poisoning by and exposure to noxious substances	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X20-X29 Contact with venomous animals and plants	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
W50-W64 Exposure to animate mechanical forces	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V80-V89 Other land transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V40-V49 Car occupant injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V20-V29 Motorcycle rider injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
R52 Pain, not elsewhere classified	0.717	0.283
T87 Complications peculiar to reattachment and amputation	0.716	0.283
T80 Complications following infusion, transfusion and therapeutic injection	0.716	0.283
N18.2 Chronic kidney disease, stage 2	0.716	0.284
Y84.8 Other medical procedures	0.716	0.284
E85 Amyloidosis	0.716	0.284
E84 Cystic fibrosis	0.716	0.284
E79 Disorders of purine and pyrimidine metabolism	0.716	0.284
E77 Disorders of glycoprotein metabolism	0.716	0.284
E76 Disorders of glycosaminoglycan metabolism	0.716	0.284
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.716	0.284
E74 Other disorders of carbohydrate metabolism	0.716	0.284
E73 Lactose intolerance	0.716	0.284
E72 Other disorders of amino-acid metabolism	0.716	0.284
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.716	0.284
E70 Disorders of aromatic amino-acid metabolism	0.716	0.284
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.716	0.284
Z45.1 Adjustment and management of infusion pump	0.716	0.284
C77.4 Inguinal and lower limb lymph nodes	0.715	0.285
J41 Simple and mucopurulent chronic bronchitis	0.714	0.285
J46 Status asthmaticus	0.714	0.285
N17.8 Other acute renal failure	0.713	0.287
N17.2 Acute renal failure with medullary necrosis	0.713	0.287
N17.1 Acute renal failure with acute cortical necrosis	0.713	0.287
N17.0 Acute renal failure with tubular necrosis	0.713	0.287
Y83.5 Amputation of limb(s)	0.713	0.287
T84.1 Mechanical complication of internal fixation device of bones of limb	0.713	0.287
H46-H48 Disorders of optic nerve and visual pathways	0.713	0.287
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.713	0.287
E87.4 Mixed disorder of acid-base balance	0.713	0.287
I23 Certain current complications following acute myocardial infarction	0.712	0.288
S90-S99 Injuries to the ankle and foot	0.712	0.288
B18 Chronic viral hepatitis	0.712	0.288
E65-E68 Obesity and other hyperalimentation	0.712	0.288
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.711	0.289
C78.4 Secondary malignant neoplasm of small intestine	0.711	0.289
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.711	0.289
C78.1 Secondary malignant neoplasm of mediastinum	0.711	0.289
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.289
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I37 Pulmonary valve disorders	0.711	0.289
I36 Nonrheumatic tricuspid valve disorders	0.711	0.289
I33 Acute and subacute endocarditis	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
I30 Acute pericarditis	0.711	0.289
J40 Bronchitis, not specified as acute or chronic	0.711	0.289
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.710	0.290
I70 Atherosclerosis	0.710	0.290
C80 Malignant neoplasm without specification of site	0.710	0.290
T15-T19 Effects of foreign body entering through natural orifice	0.709	0.291
S72.3 Fracture of shaft of femur	0.709	0.291
B99-B99 Other infectious diseases	0.709	0.291
B90-B94 Sequelae of infectious and parasitic diseases	0.709	0.291
B85-B89 Pediculosis, acariasis and other infestations	0.709	0.291
B65-B83 Helminthiases	0.709	0.291
B50-B64 Protozoal diseases	0.709	0.291
B20-B24 Human immunodeficiency virus [HIV] disease	0.709	0.291
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.709	0.291
A80-A89 Viral infections of the central nervous system	0.709	0.291
A75-A79 Rickettsioses	0.709	0.291
A70-A74 Other diseases caused by chlamydiae	0.709	0.291
A65-A69 Other spirochaetal diseases	0.709	0.291
A50-A64 Infections with a predominantly sexual mode of transmission	0.709	0.291
A20-A28 Certain zoonotic bacterial diseases	0.709	0.291
A15-A19 Tuberculosis	0.709	0.291
E07 Other disorders of thyroid	0.708	0.292
C34 Malignant neoplasm of bronchus and lung	0.707	0.293
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.706	0.294
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.706	0.294
T84.3 Mechanical complication of other bone devices, implants and grafts	0.706	0.294
T84.2 Mechanical complication of internal fixation device of other bones	0.706	0.294
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.705	0.295
M00-M03 Infectious arthropathies	0.705	0.295
Y57 Other and unspecified drugs and medicaments	0.705	0.295
J93 Pneumothorax	0.705	0.295
B95-B98 Bacterial, viral and other infectious agents	0.704	0.296
Z95.5 Presence of coronary angioplasty implant and graft	0.704	0.296
Z89 Acquired absence of limb	0.703	0.296
Z84 Family history of other conditions	0.703	0.296
Z81 Family history of mental and behavioural disorders	0.703	0.296
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.703	0.297
Z47.8 Other specified orthopaedic follow-up care	0.702	0.298
L03.2 Cellulitis of face	0.702	0.298
J20 Acute bronchitis	0.701	0.299
N30 Cystitis	0.701	0.299
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.700	0.300
M89 Other disorders of bone	0.700	0.300
Z92.9 Personal history of medical treatment, unspecified	0.699	0.300
Z92.8 Personal history of other medical treatment	0.699	0.300
Z92.5 Personal history of rehabilitation measures	0.699	0.300
H34 Retinal vascular occlusions	0.698	0.302
L10-L14 Bullous disorders	0.698	0.302
B37 Candidiasis	0.698	0.302
Z54 Convalescence	0.697	0.303
Z52 Donors of organs and tissues	0.697	0.303
Z44 Fitting and adjustment of external prosthetic device	0.697	0.303
C25 Malignant neoplasm of pancreas	0.696	0.304
J17 Pneumonia in diseases classified elsewhere	0.696	0.304
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.696	0.304
J15 Bacterial pneumonia, not elsewhere classified	0.696	0.304
J12 Viral pneumonia, not elsewhere classified	0.696	0.304
J11 Influenza, virus not identified	0.696	0.304
J10 Influenza due to identified influenza virus	0.696	0.304
J14 Pneumonia due to Haemophilus influenzae	0.696	0.304
J09 Influenza due to certain identified influenza virus	0.696	0.304
H43 Disorders of vitreous body	0.696	0.304
I44.6 Other and unspecified fascicular block	0.695	0.305
I44.5 Left posterior fascicular block	0.695	0.305
I44.4 Left anterior fascicular block	0.695	0.305
I44.3 Other and unspecified atrioventricular block	0.695	0.305
E05 Thyrotoxicosis [hyperthyroidism]	0.694	0.306
C77.5 Intrapelvic lymph nodes	0.693	0.306
Z93.3 Colostomy status	0.692	0.308
M81.99 Osteoporosis, unspecified (Site unspecified)	0.692	0.308
H32 Chorioretinal disorders in diseases classified elsewhere	0.691	0.308
H31 Other disorders of choroid	0.691	0.308
H30 Chorioretinal inflammation	0.691	0.308
I22.1 Subsequent myocardial infarction of inferior wall	0.691	0.309
C79.6 Secondary malignant neoplasm of ovary	0.691	0.309
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.691	0.309
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.691	0.309
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.691	0.309
E14 Unspecified diabetes mellitus	0.691	0.309
J43.8 Other emphysema	0.690	0.309
J43.2 Centrilobular emphysema	0.690	0.309
J43.1 Panlobular emphysema	0.690	0.309
J43.0 MacLeod's syndrome	0.690	0.309
S80 Superficial injury of lower leg	0.690	0.310
S32 Fracture of lumbar spine and pelvis	0.690	0.310
C77.1 Intrathoracic lymph nodes	0.688	0.312
I73.8 Other specified peripheral vascular diseases	0.687	0.313
I73.1 Thromboangiitis obliterans [Buerger]	0.687	0.313
Y59 Other and unspecified vaccines and biological substances	0.687	0.313
Y58 Bacterial vaccines	0.687	0.313
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.687	0.313

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations