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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs149773673
log Bayes Factor = 6.57833
Chromosome 13   position 104,749,836  (GRCh37) Explore rs149773673 on Ensembl!
Variant rs149773673 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.990 0.010 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.977 0.023 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.969 0.031 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.962 0.038 0.000
Chapter XIV Diseases of the genitourinary system
0.954 0.046 0.000
R10 Abdominal and pelvic pain
0.948 0.052 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.927 0.073 0.000
Chapter X Diseases of the respiratory system
0.925 0.075 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.923 0.077 0.000
R10.4 Other and unspecified abdominal pain
0.909 0.091 0.000
Z92 Personal history of medical treatment
0.903 0.097 0.000
R50-R69 General symptoms and signs
0.896 0.104 0.000
Chapter VI Diseases of the nervous system
0.888 0.112 0.000
J40-J47 Chronic lower respiratory diseases
0.878 0.122 0.000
K80 Cholelithiasis
0.876 0.124 0.000
M70-M79 Other soft tissue disorders
0.875 0.125 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.872 0.128 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.864 0.136 0.000
K29 Gastritis and duodenitis
0.862 0.138 0.000
Z88.0 Personal history of allergy to penicillin
0.862 0.138 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.862 0.138 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.861 0.139 0.000
K20 Oesophagitis
0.858 0.142 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.852 0.148 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.851 0.149 0.000
R00 Abnormalities of heart beat
0.851 0.149 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.850 0.150 0.000
N30-N39 Other diseases of urinary system
0.849 0.151 0.000
N17-N19 Renal failure
0.848 0.152 0.000
Z80 Family history of malignant neoplasm
0.848 0.152 0.000
R55 Syncope and collapse
0.841 0.159 0.000
K21 Gastro-oesophageal reflux disease
0.832 0.168 0.000
Chapter I Certain infectious and parasitic diseases
0.829 0.171 0.000
M20-M25 Other joint disorders
0.827 0.173 0.000
R10.3 Pain localised to other parts of lower abdomen
0.821 0.179 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.820 0.180 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.816 0.184 0.000
J45 Asthma
0.812 0.188 0.000
K22 Other diseases of oesophagus
0.811 0.189 0.000
Chapter II Neoplasms
0.808 0.192 0.000
M75 Shoulder lesions
0.808 0.192 0.000
E70-E90 Metabolic disorders
0.806 0.194 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.806 0.194 0.000
R15 Faecal incontinence
0.805 0.195 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.804 0.196 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.788 0.212 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.782 0.218 0.000
M50-M54 Other dorsopathies
0.776 0.224 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.775 0.225 0.000
N40-N51 Diseases of male genital organs
0.770 0.230 0.000
G40-G47 Episodic and paroxysmal disorders
0.764 0.236 0.000
J45.9 Asthma, unspecified
0.764 0.236 0.000
M15-M19 Arthrosis
0.762 0.237 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.762 0.238 0.000
R94 Abnormal results of function studies
0.762 0.238 0.000
R19.4 Change in bowel habit
0.761 0.239 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.754 0.245 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.752 0.248 0.000
K70-K77 Diseases of liver
0.750 0.249 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.750 0.249 0.000
R00.2 Palpitations
0.748 0.252 0.000
M45-M49 Spondylopathies
0.745 0.255 0.000
Chapter V Mental and behavioural disorders
0.745 0.255 0.000
R12 Heartburn
0.745 0.255 0.000
Chapter VII Diseases of the eye and adnexa
0.741 0.259 0.000
K90-K93 Other diseases of the digestive system
0.741 0.259 0.000
Chapter VIII Diseases of the ear and mastoid process
0.739 0.261 0.000
K29.8 Duodenitis
0.737 0.263 0.000
Z86 Personal history of certain other diseases
0.736 0.264 0.000
N18 Chronic renal failure
0.735 0.265 0.000
Z87 Personal history of other diseases and conditions
0.734 0.266 0.000
R53 Malaise and fatigue
0.734 0.266 0.000
Z96 Presence of other functional implants
0.731 0.269 0.000
M75.4 Impingement syndrome of shoulder
0.730 0.270 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.729 0.271 0.000
N20-N23 Urolithiasis
0.727 0.273 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.726 0.274 0.000
K29.7 Gastritis, unspecified
0.726 0.274 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.723 0.277 0.000
J44 Other chronic obstructive pulmonary disease
0.723 0.277 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.723 0.277 0.000
R00.0 Tachycardia, unspecified
0.723 0.277 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.719 0.281 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.716 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.716 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
R47-R49 Symptoms and signs involving speech and voice
0.716 0.284 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.716 0.284 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.716 0.284 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.716 0.284 0.000
Z98 Other postsurgical states
0.716 0.284 0.000
Z97 Presence of other devices
0.716 0.284 0.000
Z94 Transplanted organ and tissue status
0.716 0.284 0.000
Z93 Artificial opening status
0.716 0.284 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z83 Family history of other specific disorders
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
J90-J94 Other diseases of pleura
0.716 0.284 0.000
N19 Unspecified renal failure
0.714 0.286 0.000
K35-K38 Diseases of appendix
0.710 0.290 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.710 0.290 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.708 0.292 0.000
K65-K67 Diseases of peritoneum
0.707 0.293 0.000
K50-K52 Noninfective enteritis and colitis
0.705 0.294 0.000
E78.0 Pure hypercholesterolaemia
0.704 0.296 0.000
Z46 Fitting and adjustment of other devices
0.704 0.296 0.000
Chapter XX External causes of morbidity and mortality
0.703 0.297 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.700 0.299 0.000
R18 Ascites
0.700 0.299 0.000
R17 Unspecified jaundice
0.700 0.299 0.000
R14 Flatulence and related conditions
0.700 0.299 0.000
R04 Haemorrhage from respiratory passages
0.697 0.303 0.000
M20 Acquired deformities of fingers and toes
0.696 0.304 0.000
Z80.3 Family history of malignant neoplasm of breast
0.696 0.304 0.000
Z95.0 Presence of cardiac pacemaker
0.696 0.304 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.696 0.304 0.000
Z88.5 Personal history of allergy to narcotic agent
0.696 0.304 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.696 0.304 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.696 0.304 0.000
Z88.2 Personal history of allergy to sulphonamides
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
M91-M94 Chondropathies
0.695 0.305 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.695 0.305 0.000
M60-M63 Disorders of muscles
0.695 0.305 0.000
M40-M43 Deforming dorsopathies
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
N32 Other disorders of bladder
0.694 0.305 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.692 0.308 0.000
K40-K46 Hernia
0.691 0.309 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.691 0.309 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.691 0.309 0.000
R94.5 Abnormal results of liver function studies
0.691 0.309 0.000
K28 Gastrojejunal ulcer
0.690 0.310 0.000
K27 Peptic ulcer, site unspecified
0.690 0.310 0.000
K26 Duodenal ulcer
0.690 0.310 0.000
K25 Gastric ulcer
0.690 0.310 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.690 0.310 0.000
R06 Abnormalities of breathing
0.689 0.311 0.000
M80-M85 Disorders of bone density and structure
0.688 0.312 0.000
M05-M14 Inflammatory polyarthropathies
0.688 0.312 0.000
Chapter IX Diseases of the circulatory system
0.687 0.313 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.685 0.315 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.684 0.316 0.000
N99-N99 Other disorders of the genitourinary system
0.684 0.316 0.000
N60-N64 Disorders of breast
0.684 0.316 0.000
N25-N29 Other disorders of kidney and ureter
0.684 0.316 0.000
N10-N16 Renal tubulo-interstitial diseases
0.684 0.316 0.000
N00-N08 Glomerular diseases
0.684 0.316 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.684 0.316 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.684 0.316 0.000
G47 Sleep disorders
0.682 0.317 0.000
R10.2 Pelvic and perineal pain
0.679 0.320 0.000
R10.0 Acute abdomen
0.679 0.320 0.000
B95-B98 Bacterial, viral and other infectious agents
0.678 0.322 0.000
Z42 Follow-up care involving plastic surgery
0.677 0.323 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.677 0.323 0.000
J47 Bronchiectasis
0.677 0.323 0.000
K22.1 Ulcer of oesophagus
0.674 0.326 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.673 0.327 0.000
K29.5 Chronic gastritis, unspecified
0.671 0.329 0.000
Z85 Personal history of malignant neoplasm
0.670 0.330 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.669 0.331 0.000
M75.1 Rotator cuff syndrome
0.666 0.334 0.000
Z13 Special screening examination for other diseases and disorders
0.665 0.334 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.664 0.335 0.000
R01 Cardiac murmurs and other cardiac sounds
0.664 0.335 0.000
R05 Cough
0.664 0.335 0.000
R02 Gangrene, not elsewhere classified
0.664 0.335 0.000
Z88.6 Personal history of allergy to analgesic agent
0.664 0.336 0.000
J95-J99 Other diseases of the respiratory system
0.663 0.337 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.663 0.337 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.663 0.337 0.000
J60-J70 Lung diseases due to external agents
0.663 0.337 0.000
J00-J06 Acute upper respiratory infections
0.663 0.337 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.663 0.337 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.662 0.338 0.000
K86 Other diseases of pancreas
0.662 0.338 0.000
K85 Acute pancreatitis
0.662 0.338 0.000
K83 Other diseases of biliary tract
0.662 0.338 0.000
K82 Other diseases of gallbladder
0.662 0.338 0.000
K81 Cholecystitis
0.662 0.338 0.000
J30-J39 Other diseases of upper respiratory tract
0.654 0.346 0.000
Z95.1 Presence of aortocoronary bypass graft
0.651 0.349 0.000
C60-C63 Malignant neoplasms of male genital organs
0.651 0.349 0.000
Z92.9 Personal history of medical treatment, unspecified
0.648 0.352 0.000
Z92.8 Personal history of other medical treatment
0.648 0.352 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.648 0.352 0.000
Z92.5 Personal history of rehabilitation measures
0.648 0.352 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.648 0.352 0.000
Z92.3 Personal history of irradiation
0.648 0.352 0.000
Z92.0 Personal history of contraception
0.648 0.352 0.000
K31 Other diseases of stomach and duodenum
0.646 0.354 0.000
N39 Other disorders of urinary system
0.646 0.354 0.000
R07 Pain in throat and chest
0.646 0.354 0.000
N35 Urethral stricture
0.644 0.356 0.000
Z86.7 Personal history of diseases of the circulatory system
0.643 0.357 0.000
R68 Other general symptoms and signs
0.643 0.357 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.643 0.357 0.000
R62 Lack of expected normal physiological development
0.643 0.357 0.000
R61 Hyperhidrosis
0.643 0.357 0.000
R60 Oedema, not elsewhere classified
0.643 0.357 0.000
R59 Enlarged lymph nodes
0.643 0.357 0.000
R57 Shock, not elsewhere classified
0.643 0.357 0.000
R56 Convulsions, not elsewhere classified
0.643 0.357 0.000
R52 Pain, not elsewhere classified
0.643 0.357 0.000
R64 Cachexia
0.643 0.357 0.000
R58 Haemorrhage, not elsewhere classified
0.643 0.357 0.000
R54 Senility
0.643 0.357 0.000
J20-J22 Other acute lower respiratory infections
0.642 0.358 0.000
E65-E68 Obesity and other hyperalimentation
0.641 0.359 0.000
A00-A09 Intestinal infectious diseases
0.640 0.360 0.000
Z53.8 Procedure not carried out for other reasons
0.639 0.361 0.000
R10.1 Pain localised to upper abdomen
0.637 0.362 0.000
R69 Unknown and unspecified causes of morbidity
0.636 0.364 0.000
G90-G99 Other disorders of the nervous system
0.636 0.364 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.636 0.364 0.000
G70-G73 Diseases of myoneural junction and muscle
0.636 0.364 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.636 0.364 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.636 0.364 0.000
G30-G32 Other degenerative diseases of the nervous system
0.636 0.364 0.000
G20-G26 Extrapyramidal and movement disorders
0.636 0.364 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.636 0.364 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.636 0.364 0.000
J43 Emphysema
0.630 0.370 0.000
J41 Simple and mucopurulent chronic bronchitis
0.630 0.370 0.000
J46 Status asthmaticus
0.630 0.370 0.000
J42 Unspecified chronic bronchitis
0.630 0.370 0.000
J40 Bronchitis, not specified as acute or chronic
0.630 0.370 0.000
K22.7 Barrett's oesophagus
0.629 0.371 0.000
M51 Other intervertebral disk disorders
0.629 0.371 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.629 0.371 0.000
K80.3 Calculus of bile duct with cholangitis
0.628 0.372 0.000
K80.8 Other cholelithiasis
0.628 0.372 0.000
K80.4 Calculus of bile duct with cholecystitis
0.628 0.372 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.628 0.372 0.000
M77 Other enthesopathies
0.627 0.372 0.000
M76 Enthesopathies of lower limb, excluding foot
0.627 0.372 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.627 0.372 0.000
M72 Fibroblastic disorders
0.627 0.372 0.000
M71 Other bursopathies
0.627 0.372 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.627 0.372 0.000
M25 Other joint disorders, not elsewhere classified
0.627 0.373 0.000
K55-K64 Other diseases of intestines
0.626 0.374 0.000
R50 Fever of unknown origin
0.626 0.374 0.000
N18.3 Chronic kidney disease, stage 3
0.626 0.374 0.000
M17 Gonarthrosis [arthrosis of knee]
0.626 0.374 0.000
E50-E64 Other nutritional deficiencies
0.625 0.375 0.000
E40-E46 Malnutrition
0.625 0.375 0.000
E20-E35 Disorders of other endocrine glands
0.625 0.375 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.625 0.375 0.000
G47.3 Sleep apnoea
0.624 0.376 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.619 0.381 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.618 0.382 0.000
K29.9 Gastroduodenitis, unspecified
0.618 0.382 0.000
K29.4 Chronic atrophic gastritis
0.618 0.382 0.000
K29.3 Chronic superficial gastritis
0.618 0.382 0.000
K29.2 Alcoholic gastritis
0.618 0.382 0.000
K29.1 Other acute gastritis
0.618 0.382 0.000
K29.0 Acute haemorrhagic gastritis
0.618 0.382 0.000
Z54 Convalescence
0.618 0.382 0.000
Z52 Donors of organs and tissues
0.618 0.382 0.000
Z50 Care involving use of rehabilitation procedures
0.618 0.382 0.000
Z49 Care involving dialysis
0.618 0.382 0.000
Z48 Other surgical follow-up care
0.618 0.382 0.000
Z47 Other orthopaedic follow-up care
0.618 0.382 0.000
Z45 Adjustment and management of implanted device
0.618 0.382 0.000
Z44 Fitting and adjustment of external prosthetic device
0.618 0.382 0.000
Z43 Attention to artificial openings
0.618 0.382 0.000
Z41 Procedures for purposes other than remedying health state
0.618 0.382 0.000
Z40 Prophylactic surgery
0.618 0.382 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.617 0.383 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.617 0.383 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.617 0.383 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.617 0.383 0.000
M23 Internal derangement of knee
0.615 0.385 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.612 0.388 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.612 0.388 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.610 0.390 0.000
R19.6 Halitosis
0.610 0.390 0.000
R19.5 Other fecal abnormalities
0.610 0.390 0.000
R19.3 Abdominal rigidity
0.610 0.390 0.000
R19.2 Visible peristalsis
0.610 0.390 0.000
R19.1 Abnormal bowel sounds
0.610 0.390 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.610 0.390 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.610 0.390 0.000
R00.1 Bradycardia, unspecified
0.610 0.390 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.610 0.390 0.000
Z95.4 Presence of other heart-valve replacement
0.610 0.390 0.000
Z95.3 Presence of xenogenic heart valve
0.610 0.390 0.000
Z95.2 Presence of prosthetic heart valve
0.610 0.390 0.000
N37 Urethral disorders in diseases classified elsewhere
0.608 0.391 0.000
N36 Other disorders of urethra
0.608 0.391 0.000
N34 Urethritis and urethral syndrome
0.608 0.391 0.000
N33 Bladder disorders in diseases classified elsewhere
0.608 0.391 0.000
N30 Cystitis
0.608 0.391 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.608 0.392 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.608 0.392 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.608 0.392 0.000
Z80.6 Family history of leukaemia
0.608 0.392 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.608 0.392 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.608 0.392 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.608 0.392 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.608 0.392 0.000
R30-R39 Symptoms and signs involving the urinary system
0.606 0.394 0.000
G56 Mononeuropathies of upper limb
0.606 0.394 0.000
Z90.1 Acquired absence of breast(s)
0.601 0.398 0.000
R42 Dizziness and giddiness
0.601 0.399 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.600 0.400 0.000
Z37 Outcome of delivery
0.599 0.401 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.598 0.402 0.000
B99-B99 Other infectious diseases
0.595 0.405 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.595 0.405 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.595 0.405 0.000
B65-B83 Helminthiases
0.595 0.405 0.000
B50-B64 Protozoal diseases
0.595 0.405 0.000
B35-B49 Mycoses
0.595 0.405 0.000
B25-B34 Other viral diseases
0.595 0.405 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.595 0.405 0.000
B15-B19 Viral hepatitis
0.595 0.405 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.595 0.405 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.595 0.405 0.000
A80-A89 Viral infections of the central nervous system
0.595 0.405 0.000
A75-A79 Rickettsioses
0.595 0.405 0.000
A70-A74 Other diseases caused by chlamydiae
0.595 0.405 0.000
A65-A69 Other spirochaetal diseases
0.595 0.405 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.595 0.405 0.000
A30-A49 Other bacterial diseases
0.595 0.405 0.000
A20-A28 Certain zoonotic bacterial diseases
0.595 0.405 0.000
A15-A19 Tuberculosis
0.595 0.405 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.593 0.407 0.000
M35 Other systemic involvement of connective tissue
0.593 0.407 0.000
M34 Systemic sclerosis
0.593 0.407 0.000
M33 Dermatopolymyositis
0.593 0.407 0.000
M32 Systemic lupus erythematosus
0.593 0.407 0.000
M31 Other necrotising vasculopathies
0.593 0.407 0.000
M30 Polyarteritis nodosa and related conditions
0.593 0.407 0.000
M24 Other specific joint derangements
0.593 0.407 0.000
M22 Disorders of patella
0.593 0.407 0.000
M21 Other acquired deformities of limbs
0.593 0.407 0.000
R63 Symptoms and signs concerning food and fluid intake
0.592 0.408 0.000
J09-J18 Influenza and pneumonia
0.591 0.408 0.000
Z46.6 Fitting and adjustment of urinary device
0.590 0.410 0.000
N40 Hyperplasia of prostate
0.590 0.410 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.589 0.411 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.588 0.412 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.588 0.412 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.588 0.412 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.588 0.412 0.000
Z82.3 Family history of stroke
0.588 0.412 0.000
Z82.2 Family history of deafness and hearing loss
0.588 0.412 0.000
Z82.1 Family history of blindness and visual loss
0.588 0.412 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.588 0.412 0.000
E10-E14 Diabetes mellitus
0.587 0.413 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.585 0.415 0.000
Z91.7 Personal history of female genital mutilation
0.585 0.415 0.000
Z91.6 Personal history of other physical trauma
0.585 0.415 0.000
Z91.5 Personal history of self-harm
0.585 0.415 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.585 0.415 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.585 0.415 0.000
Z91.2 Personal history of poor personal hygiene
0.585 0.415 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.585 0.415 0.000
N32.8 Other specified disorders of bladder
0.584 0.416 0.000
D10-D36 Benign neoplasms
0.584 0.416 0.000
I30-I52 Other forms of heart disease
0.583 0.417 0.000
C50-C50 Malignant neoplasm of breast
0.582 0.417 0.000
J45.8 Mixed asthma
0.582 0.418 0.000
J45.1 Nonallergic asthma
0.582 0.418 0.000
J45.0 Predominantly allergic asthma
0.582 0.418 0.000
K22.9 Disease of oesophagus, unspecified
0.581 0.418 0.000
K22.8 Other specified diseases of oesophagus
0.581 0.418 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.581 0.418 0.000
K22.5 Diverticulum of oesophagus, acquired
0.581 0.418 0.000
K22.4 Dyskinesia of oesophagus
0.581 0.418 0.000
K22.3 Perforation of oesophagus
0.581 0.418 0.000
K22.2 Oesophageal obstruction
0.581 0.418 0.000
K22.0 Achalasia of cardia
0.581 0.418 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.580 0.420 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.580 0.420 0.000
E78.5 Hyperlipidaemia, unspecified
0.580 0.420 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.580 0.420 0.000
D00-D09 In situ neoplasms
0.580 0.420 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.580 0.420 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.580 0.420 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.580 0.420 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.580 0.420 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.580 0.420 0.000
C64-C68 Malignant neoplasms of urinary tract
0.580 0.420 0.000
C51-C58 Malignant neoplasms of female genital organs
0.580 0.420 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.580 0.420 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.580 0.420 0.000
C15-C26 Malignant neoplasms of digestive organs
0.580 0.420 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.580 0.420 0.000
N18.9 Chronic renal failure, unspecified
0.579 0.420 0.000
M75.8 Other shoulder lesions
0.579 0.421 0.000
M75.9 Shoulder lesion, unspecified
0.579 0.421 0.000
M75.5 Bursitis of shoulder
0.579 0.421 0.000
M75.3 Calcific tendinitis of shoulder
0.579 0.421 0.000
M75.2 Bicipital tendinitis
0.579 0.421 0.000
M75.0 Adhesive capsulitis of shoulder
0.579 0.421 0.000
K76 Other diseases of liver
0.579 0.421 0.000
N50 Other disorders of male genital organs
0.579 0.421 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.578 0.422 0.000
E88 Other metabolic disorders
0.578 0.422 0.000
E85 Amyloidosis
0.578 0.422 0.000
E84 Cystic fibrosis
0.578 0.422 0.000
E83 Disorders of mineral metabolism
0.578 0.422 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.578 0.422 0.000
E79 Disorders of purine and pyrimidine metabolism
0.578 0.422 0.000
E77 Disorders of glycoprotein metabolism
0.578 0.422 0.000
E76 Disorders of glycosaminoglycan metabolism
0.578 0.422 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.578 0.422 0.000
E74 Other disorders of carbohydrate metabolism
0.578 0.422 0.000
E73 Lactose intolerance
0.578 0.422 0.000
E72 Other disorders of amino-acid metabolism
0.578 0.422 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.578 0.422 0.000
E70 Disorders of aromatic amino-acid metabolism
0.578 0.422 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.578 0.422 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.578 0.422 0.000
Z90.8 Acquired absence of other organs
0.577 0.423 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.577 0.423 0.000
Z90.5 Acquired absence of kidney
0.577 0.423 0.000
Z90.3 Acquired absence of part of stomach
0.577 0.423 0.000
Z90.2 Acquired absence of lung [part of]
0.577 0.423 0.000
Z90.0 Acquired absence of part of head and neck
0.577 0.423 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.574 0.425 0.000
E86 Volume depletion
0.573 0.427 0.000
M19 Other arthrosis
0.573 0.427 0.000
R79 Other abnormal findings of blood chemistry
0.573 0.427 0.000
M20.4 Other hammer toe(s) (acquired)
0.571 0.429 0.000
M17.1 Other primary gonarthrosis
0.571 0.429 0.000
M54 Dorsalgia
0.570 0.430 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.569 0.431 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.569 0.431 0.000
M47 Spondylosis
0.569 0.431 0.000
R11 Nausea and vomiting
0.568 0.431 0.000
K43 Ventral hernia
0.567 0.433 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.566 0.433 0.000
J90 Pleural effusion, not elsewhere classified
0.565 0.435 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.565 0.435 0.000
Z10 Routine general health check-up of defined subpopulation
0.565 0.435 0.000
Z04 Examination and observation for other reasons
0.565 0.435 0.000
Z02 Examination and encounter for administrative purposes
0.565 0.435 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.565 0.435 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.565 0.435 0.000
N20 Calculus of kidney and ureter
0.564 0.435 0.000
K92 Other diseases of digestive system
0.562 0.438 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.560 0.439 0.000
N17 Acute renal failure
0.560 0.440 0.000
M20.5 Other deformities of toe(s) (acquired)
0.560 0.440 0.000
Z96.6 Presence of orthopaedic joint implants
0.559 0.440 0.000
R13 Dysphagia
0.557 0.442 0.000
F30-F39 Mood [affective] disorders
0.557 0.443 0.000
M53 Other dorsopathies, not elsewhere classified
0.556 0.443 0.000
M50 Cervical disk disorders
0.556 0.443 0.000
R46 Symptoms and signs involving appearance and behaviour
0.556 0.444 0.000
R45 Symptoms and signs involving emotional state
0.556 0.444 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.556 0.444 0.000
R43 Disturbances of smell and taste
0.556 0.444 0.000
R40 Somnolence, stupor and coma
0.556 0.444 0.000
M48 Other spondylopathies
0.553 0.446 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.552 0.448 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.552 0.448 0.000
N48 Other disorders of penis
0.552 0.448 0.000
N45 Orchitis and epididymitis
0.552 0.448 0.000
N43 Hydrocele and spermatocele
0.552 0.448 0.000
N42 Other disorders of prostate
0.552 0.448 0.000
N41 Inflammatory diseases of prostate
0.552 0.448 0.000
N46 Male infertility
0.552 0.448 0.000
N44 Torsion of testis
0.552 0.448 0.000
H90-H95 Other disorders of ear
0.551 0.448 0.000
E00-E07 Disorders of thyroid gland
0.551 0.449 0.000
N39.0 Urinary tract infection, site not specified
0.551 0.449 0.000
N73 Other female pelvic inflammatory diseases
0.550 0.449 0.000
H25-H28 Disorders of lens
0.550 0.450 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.548 0.452 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.548 0.452 0.000
G44 Other headache syndromes
0.548 0.452 0.000
G43 Migraine
0.548 0.452 0.000
G41 Status epilepticus
0.548 0.452 0.000
M18 Arthrosis of first carpometacarpal joint
0.547 0.453 0.000
M15 Polyarthrosis
0.547 0.453 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.546 0.454 0.000
L50-L54 Urticaria and erythema
0.546 0.454 0.000
L40-L45 Papulosquamous disorders
0.546 0.454 0.000
L20-L30 Dermatitis and eczema
0.546 0.454 0.000
L10-L14 Bullous disorders
0.546 0.454 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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