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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16838078
log Bayes Factor = 13.5832
Chromosome 1   position 157,069,261  (GRCh37) Explore rs16838078 on Ensembl!
Variant rs16838078 is part of Cluster X0120

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
Z87 Personal history of other diseases and conditions
0.998 0.002 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.998 0.002 0.000
D25 Leiomyoma of uterus
0.997 0.003 0.000
D25.9 Leiomyoma of uterus, unspecified
0.997 0.003 0.000
M54 Dorsalgia
0.997 0.003 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
M45-M49 Spondylopathies
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
R94 Abnormal results of function studies
0.983 0.017 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.977 0.023 0.000
Z92 Personal history of medical treatment
0.973 0.027 0.000
M54.9 Dorsalgia, unspecified
0.972 0.028 0.000
R94.5 Abnormal results of liver function studies
0.961 0.039 0.000
Z83 Family history of other specific disorders
0.955 0.045 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.954 0.046 0.000
M48 Other spondylopathies
0.953 0.047 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.951 0.049 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.951 0.049 0.000
Z87.1 Personal history of diseases of the digestive system
0.942 0.058 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.941 0.059 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.939 0.061 0.000
Z12 Special screening examination for neoplasms
0.936 0.063 0.000
M54.3 Sciatica
0.933 0.067 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.933 0.067 0.000
M48.0 Spinal stenosis
0.932 0.068 0.000
Z04 Examination and observation for other reasons
0.928 0.072 0.000
Z83.7 Family history of diseases of the digestive system
0.927 0.073 0.000
F17.1 Harmful use
0.924 0.076 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.922 0.078 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.921 0.079 0.000
S60-S69 Injuries to the wrist and hand
0.917 0.083 0.000
Z92.3 Personal history of irradiation
0.916 0.084 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.908 0.092 0.000
Chapter XIV Diseases of the genitourinary system
0.907 0.093 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.906 0.094 0.000
N40-N51 Diseases of male genital organs
0.905 0.095 0.000
E00-E07 Disorders of thyroid gland
0.900 0.100 0.000
N50 Other disorders of male genital organs
0.897 0.103 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.895 0.105 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.893 0.107 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.893 0.107 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.892 0.108 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.891 0.109 0.000
C51-C58 Malignant neoplasms of female genital organs
0.889 0.110 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.888 0.112 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.888 0.112 0.000
Chapter I Certain infectious and parasitic diseases
0.887 0.113 0.000
N50.8 Other specified disorders of male genital organs
0.887 0.113 0.000
M48.06 Spinal stenosis (Lumbar region)
0.886 0.114 0.000
F30-F39 Mood [affective] disorders
0.885 0.115 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.882 0.118 0.000
Z93 Artificial opening status
0.882 0.118 0.000
D18 Haemangioma and lymphangioma, any site
0.881 0.119 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.879 0.121 0.000
C80 Malignant neoplasm without specification of site
0.876 0.124 0.000
C79 Secondary malignant neoplasm of other sites
0.875 0.125 0.000
D00-D09 In situ neoplasms
0.875 0.125 0.000
D12.8 Rectum
0.874 0.126 0.000
A30-A49 Other bacterial diseases
0.871 0.129 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.867 0.133 0.000
M54.1 Radiculopathy
0.866 0.134 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.866 0.134 0.000
D12.2 Ascending colon
0.864 0.136 0.000
S61 Open wound of wrist and hand
0.861 0.139 0.000
E03 Other hypothyroidism
0.858 0.142 0.000
M54.2 Cervicalgia
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.854 0.146 0.000
F10.1 Harmful use
0.852 0.148 0.000
N41 Inflammatory diseases of prostate
0.850 0.150 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.848 0.152 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.847 0.153 0.000
M40-M43 Deforming dorsopathies
0.846 0.154 0.000
F10.0 Acute intoxication
0.845 0.155 0.000
Z98 Other postsurgical states
0.843 0.157 0.000
M54.36 Sciatica (Lumbar region)
0.838 0.162 0.000
S00-S09 Injuries to the head
0.837 0.163 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.836 0.164 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.834 0.166 0.000
D12.3 Transverse colon
0.833 0.167 0.000
N72 Inflammatory disease of cervix uteri
0.830 0.170 0.000
Z04.1 Examination and observation following transport accident
0.826 0.174 0.000
R87 Abnormal findings in specimens from female genital organs
0.826 0.174 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.824 0.176 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.824 0.176 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.819 0.181 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.818 0.182 0.000
Z04.8 Examination and observation for other specified reasons
0.817 0.183 0.000
R94.4 Abnormal results of kidney function studies
0.817 0.183 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.816 0.184 0.000
M80-M85 Disorders of bone density and structure
0.816 0.184 0.000
R94.3 Abnormal results of cardiovascular function studies
0.816 0.184 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.815 0.185 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.815 0.185 0.000
M47 Spondylosis
0.815 0.185 0.000
E03.9 Hypothyroidism, unspecified
0.813 0.187 0.000
A41 Other septicaemia
0.813 0.187 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.811 0.189 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.809 0.191 0.000
M53 Other dorsopathies, not elsewhere classified
0.809 0.191 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.808 0.192 0.000
M54.39 Sciatica (Site unspecified)
0.807 0.193 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.807 0.193 0.000
Z93.2 Ileostomy status
0.806 0.194 0.000
Z03.8 Observation for other suspected diseases and conditions
0.805 0.195 0.000
Z03.4 Observation for suspected myocardial infarction
0.804 0.196 0.000
D36 Benign neoplasm of other and unspecified sites
0.803 0.197 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.802 0.198 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.802 0.198 0.000
D29 Benign neoplasm of male genital organs
0.800 0.200 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.797 0.203 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.796 0.204 0.000
C77.2 Intra-abdominal lymph nodes
0.796 0.204 0.000
D18.0 Haemangioma, any site
0.796 0.204 0.000
D12.6 Colon, unspecified
0.796 0.204 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
C54 Malignant neoplasm of corpus uteri
0.795 0.205 0.000
Z83.5 Family history of eye and ear disorders
0.794 0.206 0.000
F32 Depressive episode
0.793 0.207 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.792 0.207 0.000
N50.0 Atrophy of testis
0.792 0.208 0.000
M15-M19 Arthrosis
0.790 0.210 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.788 0.212 0.000
C15-C26 Malignant neoplasms of digestive organs
0.787 0.213 0.000
N45 Orchitis and epididymitis
0.786 0.214 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.786 0.214 0.000
D32 Benign neoplasm of meninges
0.785 0.215 0.000
C77.4 Inguinal and lower limb lymph nodes
0.783 0.217 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.783 0.217 0.000
R90.0 Intracranial space-occupying lesion
0.782 0.218 0.000
D12.7 Rectosigmoid junction
0.781 0.219 0.000
M51 Other intervertebral disk disorders
0.780 0.220 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.780 0.220 0.000
R41.3 Other amnesia
0.778 0.222 0.000
Z87.8 Personal history of other specified conditions
0.777 0.223 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.774 0.226 0.000
M46 Other inflammatory spondylopathies
0.774 0.226 0.000
M48.02 Spinal stenosis (Cervical region)
0.774 0.226 0.000
Z13 Special screening examination for other diseases and disorders
0.773 0.227 0.000
R25 Abnormal involuntary movements
0.773 0.227 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.773 0.227 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.770 0.230 0.000
S80-S89 Injuries to the knee and lower leg
0.767 0.233 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.767 0.233 0.000
D46 Myelodysplastic syndromes
0.765 0.235 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.765 0.235 0.000
Z94 Transplanted organ and tissue status
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.762 0.237 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.762 0.238 0.000
S20-S29 Injuries to the thorax
0.759 0.241 0.000
M54.22 Cervicalgia (Cervical region)
0.758 0.242 0.000
N76 Other inflammation of vagina and vulva
0.756 0.244 0.000
A46 Erysipelas
0.755 0.245 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.755 0.245 0.000
F32.9 Depressive episode, unspecified
0.754 0.246 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.754 0.246 0.000
S61.0 Open wound of finger(s) without damage to nail
0.754 0.246 0.000
Chapter XX External causes of morbidity and mortality
0.754 0.246 0.000
D17 Benign lipomatous neoplasm
0.754 0.246 0.000
C77.5 Intrapelvic lymph nodes
0.753 0.247 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.753 0.247 0.000
E04 Other non-toxic goitre
0.752 0.248 0.000
S02 Fracture of skull and facial bones
0.751 0.249 0.000
Z92.8 Personal history of other medical treatment
0.751 0.249 0.000
E07 Other disorders of thyroid
0.751 0.249 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.751 0.249 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.750 0.250 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.749 0.250 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.749 0.251 0.000
M20-M25 Other joint disorders
0.748 0.252 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.747 0.253 0.000
Z98.1 Arthrodesis status
0.746 0.254 0.000
M00-M03 Infectious arthropathies
0.746 0.254 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.746 0.254 0.000
N41.1 Chronic prostatitis
0.745 0.255 0.000
R87.6 Abnormal cytological findings
0.744 0.256 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.744 0.256 0.000
M45 Ankylosing spondylitis
0.744 0.256 0.000
S40-S49 Injuries to the shoulder and upper arm
0.744 0.256 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.743 0.257 0.000
M54.4 Lumbago with sciatica
0.740 0.260 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.739 0.261 0.000
Z93.1 Gastrostomy status
0.738 0.262 0.000
Z87.0 Personal history of diseases of the respiratory system
0.738 0.262 0.000
R40 Somnolence, stupor and coma
0.738 0.262 0.000
Z57 Occupational exposure to risk-factors
0.737 0.263 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.736 0.264 0.000
S61.8 Open wound of other parts of wrist and hand
0.735 0.265 0.000
F31 Bipolar affective disorder
0.734 0.266 0.000
D26 Other benign neoplasms of uterus
0.732 0.268 0.000
Z93.8 Other artificial opening status
0.731 0.269 0.000
R20 Disturbances of skin sensation
0.731 0.269 0.000
M54.16 Radiculopathy (Lumbar region)
0.730 0.270 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.730 0.270 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.729 0.271 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.728 0.272 0.000
R41.0 Disorientation, unspecified
0.727 0.273 0.000
D12.9 Anus and anal canal
0.727 0.273 0.000
C54.1 Endometrium
0.727 0.273 0.000
N42 Other disorders of prostate
0.725 0.275 0.000
D04 Carcinoma in situ of skin
0.724 0.276 0.000
C92 Myeloid leukaemia
0.723 0.277 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.723 0.277 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.722 0.277 0.000
D05 Carcinoma in situ of breast
0.722 0.278 0.000
N70 Salpingitis and oophoritis
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.721 0.279 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.721 0.279 0.000
M70-M79 Other soft tissue disorders
0.721 0.279 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.721 0.279 0.000
M41 Scoliosis
0.721 0.279 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.720 0.280 0.000
D41.4 Bladder
0.720 0.280 0.000
Z89 Acquired absence of limb
0.719 0.281 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.718 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.284 0.000
D30 Benign neoplasm of urinary organs
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.284 0.000
B35-B49 Mycoses
0.715 0.285 0.000
C77.8 Lymph nodes of multiple regions
0.715 0.285 0.000
M54.8 Other dorsalgia
0.714 0.285 0.000
M54.6 Pain in thoracic spine
0.714 0.285 0.000
M54.0 Panniculitis affecting regions of neck and back
0.714 0.285 0.000
C80.9 Malignant neoplasm, unspecified
0.714 0.286 0.000
C78.2 Secondary malignant neoplasm of pleura
0.713 0.287 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
Z96 Presence of other functional implants
0.712 0.288 0.000
M05-M14 Inflammatory polyarthropathies
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.712 0.288 0.000
M47.2 Other spondylosis with radiculopathy
0.711 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.711 0.289 0.000
D27 Benign neoplasm of ovary
0.711 0.289 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.290 0.000
F70-F79 Mental retardation
0.709 0.290 0.000
M49 Spondylopathies in diseases classified elsewhere
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.705 0.295 0.000
R94.7 Abnormal results of other endocrine function studies
0.705 0.295 0.000
R94.6 Abnormal results of thyroid function studies
0.705 0.295 0.000
R94.2 Abnormal results of pulmonary function studies
0.705 0.295 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.705 0.295 0.000
R94.0 Abnormal results of function studies of central nervous system
0.705 0.295 0.000
Z98.0 Intestinal bypass and anastomosis status
0.704 0.296 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.704 0.296 0.000
N43 Hydrocele and spermatocele
0.703 0.297 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.297 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.297 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.297 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.702 0.297 0.000
F11 Mental and behavioural disorders due to use of opioids
0.702 0.297 0.000
Z92.0 Personal history of contraception
0.702 0.298 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.701 0.299 0.000
D12.1 Appendix
0.701 0.299 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
F60-F69 Disorders of adult personality and behaviour
0.699 0.301 0.000
D25.1 Intramural leiomyoma of uterus
0.699 0.301 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.301 0.000
M54.12 Radiculopathy (Cervical region)
0.698 0.301 0.000
C81 Hodgkin's disease
0.698 0.302 0.000
Z92.9 Personal history of medical treatment, unspecified
0.698 0.302 0.000
Z92.5 Personal history of rehabilitation measures
0.698 0.302 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.698 0.302 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.697 0.303 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.697 0.303 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.697 0.303 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.697 0.303 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.697 0.303 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.697 0.303 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.697 0.303 0.000
D25.0 Submucous leiomyoma of uterus
0.696 0.304 0.000
E05.9 Thyrotoxicosis, unspecified
0.695 0.305 0.000
Z01.6 Radiological examination, not elsewhere classified
0.694 0.306 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.694 0.306 0.000
E03.8 Other specified hypothyroidism
0.693 0.307 0.000
A49 Bacterial infection of unspecified site
0.693 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.692 0.308 0.000
R86 Abnormal findings in specimens from male genital organs
0.692 0.308 0.000
R20.2 Paraesthesia of skin
0.689 0.311 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.689 0.311 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.689 0.311 0.000
F10.4 Withdrawal state with delirium
0.688 0.312 0.000
A48 Other bacterial diseases, not elsewhere classified
0.687 0.313 0.000
Z57.2 Occupational exposure to dust
0.687 0.313 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.687 0.313 0.000
D12.4 Descending colon
0.686 0.314 0.000
D45 Polycythaemia vera
0.686 0.314 0.000
Z83.6 Family history of diseases of the respiratory system
0.684 0.315 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.684 0.315 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.684 0.315 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.684 0.315 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.684 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.684 0.316 0.000
R29.6 Tendency to fall, not elsewhere classified
0.684 0.316 0.000
A41.9 Septicaemia, unspecified
0.683 0.317 0.000
M48.9 Spondylopathy, unspecified
0.683 0.317 0.000
M48.8 Other specified spondylopathies
0.683 0.317 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.683 0.317 0.000
M48.4 Fatigue fracture of vertebra
0.683 0.317 0.000
M48.3 Traumatic spondylopathy
0.683 0.317 0.000
M48.2 Kissing spine
0.683 0.317 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.683 0.317 0.000
S92 Fracture of foot, except ankle
0.683 0.317 0.000
S32 Fracture of lumbar spine and pelvis
0.683 0.317 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.682 0.318 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.682 0.318 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.682 0.318 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.682 0.318 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.682 0.318 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.682 0.318 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.682 0.318 0.000
D10 Benign neoplasm of mouth and pharynx
0.681 0.319 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.681 0.319 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.319 0.000
S09 Other and unspecified injuries of head
0.680 0.320 0.000
M48.09 Spinal stenosis (Site unspecified)
0.679 0.320 0.000
C53 Malignant neoplasm of cervix uteri
0.679 0.321 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.679 0.321 0.000
M19 Other arthrosis
0.678 0.322 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.678 0.322 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.677 0.323 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.677 0.323 0.000
S70-S79 Injuries to the hip and thigh
0.676 0.324 0.000
F10.3 Withdrawal state
0.676 0.324 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.675 0.325 0.000
R46 Symptoms and signs involving appearance and behaviour
0.675 0.325 0.000
R43 Disturbances of smell and taste
0.675 0.325 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.674 0.326 0.000
Z04.9 Examination and observation for unspecified reason
0.674 0.326 0.000
N73 Other female pelvic inflammatory diseases
0.674 0.326 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.674 0.326 0.000
F17.9 Unspecified mental and behavioural disorder
0.673 0.326 0.000
F17.8 Other mental and behavioural disorders
0.673 0.326 0.000
F17.7 Residual and late-onset psychotic disorder
0.673 0.326 0.000
F17.6 Amnesic syndrome
0.673 0.326 0.000
F17.5 Psychotic disorder
0.673 0.326 0.000
F17.4 Withdrawal state with delirium
0.673 0.326 0.000
F17.3 Withdrawal state
0.673 0.326 0.000
F17.0 Acute intoxication
0.673 0.326 0.000
R41.2 Retrograde amnesia
0.674 0.326 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.673 0.327 0.000
C77.0 Lymph nodes of head, face and neck
0.672 0.327 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.672 0.328 0.000
E04.9 Non-toxic goitre, unspecified
0.672 0.328 0.000
M54.5 Low back pain
0.672 0.328 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.671 0.328 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.671 0.328 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.671 0.328 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.671 0.328 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.671 0.328 0.000
Z12.3 Special screening examination for neoplasm of breast
0.671 0.328 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.671 0.328 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.671 0.328 0.000
Chapter VIII Diseases of the ear and mastoid process
0.671 0.329 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.669 0.331 0.000
M54.37 Sciatica (Lumbosacral region)
0.669 0.331 0.000
M54.35 Sciatica (Thoracolumbar region)
0.669 0.331 0.000
M54.34 Sciatica-Thoracic
0.669 0.331 0.000
M54.33 Sciatica-Cervicothoracic
0.669 0.331 0.000
M54.32 Sciatica-Cervical
0.669 0.331 0.000
M54.31 Sciatica-Occipit-atl-axl
0.669 0.331 0.000
M54.30 Sciatica (Multiple sites in spine)
0.669 0.331 0.000
F10.9 Unspecified mental and behavioural disorder
0.669 0.331 0.000
F10.8 Other mental and behavioural disorders
0.669 0.331 0.000
F10.7 Residual and late-onset psychotic disorder
0.669 0.331 0.000
F10.6 Amnesic syndrome
0.669 0.331 0.000
F10.5 Psychotic disorder
0.669 0.331 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.668 0.332 0.000
D41.0 Kidney
0.668 0.332 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.668 0.332 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.668 0.332 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.668 0.332 0.000
M48.04 Spinal stenosis (Thoracic region)
0.668 0.332 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.668 0.332 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.668 0.332 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.668 0.332 0.000
A40 Streptococcal septicaemia
0.668 0.332 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.668 0.332 0.000
D09 Carcinoma in situ of other and unspecified sites
0.666 0.334 0.000
S69 Other and unspecified injuries of wrist and hand
0.666 0.334 0.000
Z04.6 General psychiatric examination, requested by authority
0.665 0.334 0.000
Z04.5 Examination and observation following other inflicted injury
0.665 0.334 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.665 0.334 0.000
Z04.2 Examination and observation following work accident
0.665 0.334 0.000
Z04.0 Blood-alcohol and blood-drug test
0.665 0.334 0.000
D48.7 Other specified sites
0.664 0.336 0.000
R45 Symptoms and signs involving emotional state
0.664 0.336 0.000
R27 Other lack of coordination
0.663 0.337 0.000
Z03.3 Observation for suspected nervous system disorder
0.663 0.337 0.000
R87.7 Abnormal histological findings
0.662 0.338 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.661 0.339 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.661 0.339 0.000
Z03.0 Observation for suspected tuberculosis
0.661 0.339 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.661 0.339 0.000
S00 Superficial injury of head
0.660 0.340 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.658 0.342 0.000
D29.1 Prostate
0.658 0.342 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.657 0.343 0.000
S65 Injury of blood vessels at wrist and hand level
0.657 0.343 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.657 0.343 0.000
N41.0 Acute prostatitis
0.656 0.344 0.000
D11 Benign neoplasm of major salivary glands
0.655 0.345 0.000
C77.1 Intrathoracic lymph nodes
0.654 0.346 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.654 0.346 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.346 0.000
D48.1 Connective and other soft tissue
0.653 0.347 0.000
Z00.0 General medical examination
0.653 0.347 0.000
Z96.8 Presence of other specified functional implants
0.653 0.347 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.651 0.349 0.000
E40-E46 Malnutrition
0.651 0.349 0.000
D12.0 Caecum
0.651 0.349 0.000
Z02 Examination and encounter for administrative purposes
0.650 0.350 0.000
T85.2 Mechanical complication of intraocular lens
0.650 0.350 0.000
M50 Cervical disk disorders
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.650 0.350 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.649 0.350 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.649 0.350 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.649 0.350 0.000
R83 Abnormal findings in cerebrospinal fluid
0.649 0.350 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.649 0.350 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.649 0.351 0.000
N46 Male infertility
0.649 0.351 0.000
N44 Torsion of testis
0.649 0.351 0.000
M18 Arthrosis of first carpometacarpal joint
0.647 0.353 0.000
C90.0 Multiple myeloma
0.647 0.353 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.646 0.354 0.000
E00 Congenital iodine-deficiency syndrome
0.646 0.354 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.646 0.354 0.000
S64 Injury of nerves at wrist and hand level
0.646 0.354 0.000
E07.9 Disorder of thyroid, unspecified
0.644 0.356 0.000
R80 Isolated proteinuria
0.644 0.356 0.000
S67 Crushing injury of wrist and hand
0.643 0.356 0.000
N50.9 Disorder of male genital organs, unspecified
0.643 0.357 0.000
F52.2 Failure of genital response
0.643 0.357 0.000
Z90.8 Acquired absence of other organs
0.642 0.358 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
R29.4 Clicking hip
0.642 0.358 0.000
R29.3 Abnormal posture
0.642 0.358 0.000
R29.2 Abnormal reflex
0.642 0.358 0.000
R29.1 Meningismus
0.642 0.358 0.000
R29.0 Tetany
0.642 0.358 0.000
Z97 Presence of other devices
0.641 0.359 0.000
N76.0 Acute vaginitis
0.641 0.359 0.000
D32.0 Cerebral meninges
0.640 0.360 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.640 0.360 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.639 0.361 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.639 0.361 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.639 0.361 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.639 0.361 0.000
R41.1 Anterograde amnesia
0.639 0.361 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.639 0.361 0.000
S02.1 Fracture of base of skull
0.639 0.361 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.638 0.362 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.638 0.362 0.000
C51 Malignant neoplasm of vulva
0.638 0.362 0.000
C58 Malignant neoplasm of placenta
0.638 0.362 0.000
C52 Malignant neoplasm of vagina
0.638 0.362 0.000
M84 Disorders of continuity of bone
0.638 0.362 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.637 0.363 0.000
C95 Leukaemia of unspecified cell type
0.637 0.363 0.000
C94 Other leukaemias of specified cell type
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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