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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16895802
log Bayes Factor = 8.13994
Chromosome 4   position 17,815,889  (GRCh37) Explore rs16895802 on Ensembl!
Variant rs16895802 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.978 0.022 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.950 0.050 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.941 0.059 0.000
K55-K64 Other diseases of intestines
0.932 0.068 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.927 0.073 0.000
E70-E90 Metabolic disorders
0.926 0.074 0.000
Chapter VII Diseases of the eye and adnexa
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.916 0.084 0.000
E11 Non-insulin-dependent diabetes mellitus
0.915 0.085 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.913 0.087 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
I44 Atrioventricular and left bundle-branch block
0.908 0.092 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.907 0.093 0.000
I34 Nonrheumatic mitral valve disorders
0.906 0.094 0.000
I35 Nonrheumatic aortic valve disorders
0.904 0.096 0.000
K90-K93 Other diseases of the digestive system
0.903 0.097 0.000
K22 Other diseases of oesophagus
0.899 0.101 0.000
R30-R39 Symptoms and signs involving the urinary system
0.892 0.108 0.000
I10-I15 Hypertensive diseases
0.892 0.108 0.000
Z95.0 Presence of cardiac pacemaker
0.888 0.112 0.000
E10 Insulin-dependent diabetes mellitus
0.885 0.115 0.000
Z98 Other postsurgical states
0.873 0.127 0.000
Chapter XIV Diseases of the genitourinary system
0.869 0.131 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.867 0.133 0.000
I20-I25 Ischaemic heart diseases
0.864 0.136 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.860 0.140 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.858 0.142 0.000
Z93 Artificial opening status
0.857 0.143 0.000
Z86 Personal history of certain other diseases
0.848 0.152 0.000
I35.0 Aortic (valve) stenosis
0.847 0.153 0.000
E78.0 Pure hypercholesterolaemia
0.845 0.155 0.000
Z95.1 Presence of aortocoronary bypass graft
0.839 0.161 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.836 0.164 0.000
K60 Fissure and fistula of anal and rectal regions
0.836 0.164 0.000
K22.7 Barrett's oesophagus
0.835 0.165 0.000
K22.1 Ulcer of oesophagus
0.832 0.168 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.830 0.170 0.000
E14 Unspecified diabetes mellitus
0.829 0.171 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.829 0.171 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.828 0.172 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.826 0.174 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.826 0.174 0.000
I10 Essential (primary) hypertension
0.825 0.175 0.000
Z02 Examination and encounter for administrative purposes
0.824 0.176 0.000
R39 Other symptoms and signs involving the urinary system
0.823 0.177 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.820 0.180 0.000
I44.0 Atrioventricular block, first degree
0.818 0.182 0.000
I34.0 Mitral (valve) insufficiency
0.812 0.188 0.000
K70-K77 Diseases of liver
0.812 0.188 0.000
Chapter VI Diseases of the nervous system
0.811 0.189 0.000
K90 Intestinal malabsorption
0.808 0.192 0.000
Z95.4 Presence of other heart-valve replacement
0.806 0.194 0.000
I25 Chronic ischaemic heart disease
0.804 0.196 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.803 0.197 0.000
Z97 Presence of other devices
0.801 0.199 0.000
K50-K52 Noninfective enteritis and colitis
0.800 0.200 0.000
I51 Complications and ill-defined descriptions of heart disease
0.800 0.200 0.000
E11.9 Without complications
0.796 0.204 0.000
H53-H54 Visual disturbances and blindness
0.793 0.207 0.000
K59 Other functional intestinal disorders
0.791 0.209 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.790 0.210 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.789 0.211 0.000
Z98.0 Intestinal bypass and anastomosis status
0.779 0.221 0.000
E20-E35 Disorders of other endocrine glands
0.779 0.221 0.000
S60-S69 Injuries to the wrist and hand
0.778 0.222 0.000
K31 Other diseases of stomach and duodenum
0.777 0.223 0.000
H25-H28 Disorders of lens
0.777 0.223 0.000
I05-I09 Chronic rheumatic heart diseases
0.777 0.223 0.000
E10.9 Without complications
0.776 0.223 0.000
I45 Other conduction disorders
0.774 0.226 0.000
E11.5 With peripheral circulatory complications
0.774 0.226 0.000
K65-K67 Diseases of peritoneum
0.773 0.227 0.000
H90-H95 Other disorders of ear
0.772 0.228 0.000
K61 Abscess of anal and rectal regions
0.770 0.230 0.000
Z86.4 Personal history of psychoactive substance abuse
0.769 0.231 0.000
Chapter XX External causes of morbidity and mortality
0.768 0.232 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.765 0.235 0.000
N30-N39 Other diseases of urinary system
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.764 0.236 0.000
Z02.8 Other examinations for administrative purposes
0.760 0.240 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.756 0.244 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.755 0.245 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.755 0.245 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.754 0.246 0.000
R20 Disturbances of skin sensation
0.752 0.248 0.000
Z83 Family history of other specific disorders
0.750 0.250 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.750 0.250 0.000
R35 Polyuria
0.750 0.250 0.000
N40-N51 Diseases of male genital organs
0.749 0.251 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.749 0.251 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.748 0.252 0.000
H65-H75 Diseases of middle ear and mastoid
0.747 0.253 0.000
E50-E64 Other nutritional deficiencies
0.747 0.253 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.746 0.254 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.745 0.255 0.000
Z87 Personal history of other diseases and conditions
0.745 0.255 0.000
K90.0 Coeliac disease
0.740 0.260 0.000
I34.1 Mitral (valve) prolapse
0.737 0.263 0.000
K60.3 Anal fistula
0.732 0.268 0.000
E10.3 With ophthalmic complications
0.731 0.269 0.000
K22.9 Disease of oesophagus, unspecified
0.729 0.271 0.000
I49 Other cardiac arrhythmias
0.729 0.271 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.728 0.272 0.000
I44.2 Atrioventricular block, complete
0.727 0.273 0.000
Chapter I Certain infectious and parasitic diseases
0.727 0.273 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.724 0.276 0.000
E14.9 Without complications
0.722 0.278 0.000
I50 Heart failure
0.722 0.278 0.000
Z96 Presence of other functional implants
0.722 0.278 0.000
H25 Senile cataract
0.720 0.280 0.000
K56.6 Other and unspecified intestinal obstruction
0.719 0.281 0.000
R32 Unspecified urinary incontinence
0.718 0.282 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
K35-K38 Diseases of appendix
0.714 0.286 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.714 0.286 0.000
Z04 Examination and observation for other reasons
0.712 0.287 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.712 0.287 0.000
Z94 Transplanted organ and tissue status
0.712 0.287 0.000
Z89 Acquired absence of limb
0.712 0.287 0.000
Z84 Family history of other conditions
0.712 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.287 0.000
E40-E46 Malnutrition
0.712 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I46 Cardiac arrest
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I42 Cardiomyopathy
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I33 Acute and subacute endocarditis
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
I31 Other diseases of pericardium
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
I38 Endocarditis, valve unspecified
0.712 0.288 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.711 0.289 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.709 0.291 0.000
K50 Crohn's disease [regional enteritis]
0.708 0.292 0.000
Z95.3 Presence of xenogenic heart valve
0.708 0.292 0.000
Chapter II Neoplasms
0.708 0.292 0.000
Z93.3 Colostomy status
0.708 0.292 0.000
E11.3 With ophthalmic complications
0.707 0.293 0.000
Z43 Attention to artificial openings
0.707 0.293 0.000
Z50 Care involving use of rehabilitation procedures
0.707 0.293 0.000
H30-H36 Disorders of choroid and retina
0.707 0.293 0.000
L20-L30 Dermatitis and eczema
0.706 0.294 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.706 0.294 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.705 0.295 0.000
H60-H62 Diseases of external ear
0.705 0.295 0.000
E86 Volume depletion
0.704 0.296 0.000
E83 Disorders of mineral metabolism
0.704 0.296 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.701 0.299 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.700 0.300 0.000
H53 Visual disturbances
0.698 0.301 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.698 0.302 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.698 0.302 0.000
Z93.2 Ileostomy status
0.697 0.303 0.000
N32 Other disorders of bladder
0.695 0.305 0.000
I83 Varicose veins of lower extremities
0.694 0.306 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
E11.4 With neurological complications
0.692 0.308 0.000
L03 Cellulitis
0.692 0.308 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.691 0.309 0.000
K63 Other diseases of intestine
0.690 0.310 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.688 0.312 0.000
Z95.2 Presence of prosthetic heart valve
0.688 0.312 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.685 0.315 0.000
I47 Paroxysmal tachycardia
0.685 0.315 0.000
K40-K46 Hernia
0.684 0.316 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.684 0.316 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.684 0.316 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.681 0.319 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.681 0.319 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.680 0.320 0.000
I51.7 Cardiomegaly
0.679 0.321 0.000
K31.7 Polyp of stomach and duodenum
0.679 0.321 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.679 0.321 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.679 0.321 0.000
K60.2 Anal fissure, unspecified
0.678 0.322 0.000
L50-L54 Urticaria and erythema
0.677 0.323 0.000
M45-M49 Spondylopathies
0.673 0.327 0.000
S00-S09 Injuries to the head
0.672 0.328 0.000
M50-M54 Other dorsopathies
0.671 0.329 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.668 0.332 0.000
K55 Vascular disorders of intestine
0.668 0.332 0.000
R47-R49 Symptoms and signs involving speech and voice
0.666 0.333 0.000
M15-M19 Arthrosis
0.666 0.334 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.665 0.335 0.000
K28 Gastrojejunal ulcer
0.665 0.335 0.000
K27 Peptic ulcer, site unspecified
0.665 0.335 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.665 0.335 0.000
I44.7 Left bundle-branch block, unspecified
0.664 0.336 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.664 0.336 0.000
E88 Other metabolic disorders
0.664 0.336 0.000
E85 Amyloidosis
0.664 0.336 0.000
E84 Cystic fibrosis
0.664 0.336 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.664 0.336 0.000
E79 Disorders of purine and pyrimidine metabolism
0.664 0.336 0.000
E77 Disorders of glycoprotein metabolism
0.664 0.336 0.000
E76 Disorders of glycosaminoglycan metabolism
0.664 0.336 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.664 0.336 0.000
E74 Other disorders of carbohydrate metabolism
0.664 0.336 0.000
E73 Lactose intolerance
0.664 0.336 0.000
E72 Other disorders of amino-acid metabolism
0.664 0.336 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.664 0.336 0.000
E70 Disorders of aromatic amino-acid metabolism
0.664 0.336 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.664 0.336 0.000
H55-H59 Other disorders of eye and adnexa
0.664 0.336 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.664 0.336 0.000
H43-H45 Disorders of vitreous body and globe
0.664 0.336 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.664 0.336 0.000
H10-H13 Disorders of conjunctiva
0.664 0.336 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.663 0.337 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.663 0.337 0.000
K20 Oesophagitis
0.662 0.338 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.661 0.339 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.661 0.339 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.660 0.340 0.000
R21 Rash and other nonspecific skin eruption
0.660 0.340 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.660 0.340 0.000
H80-H83 Diseases of inner ear
0.658 0.342 0.000
L10-L14 Bullous disorders
0.656 0.343 0.000
E11.8 With unspecified complications
0.656 0.344 0.000
E11.7 With multiple complications
0.656 0.344 0.000
E11.6 With other specified complications
0.656 0.344 0.000
E11.2 With renal complications
0.656 0.344 0.000
E11.1 With ketoacidosis
0.656 0.344 0.000
E11.0 With coma
0.656 0.344 0.000
N41 Inflammatory diseases of prostate
0.656 0.344 0.000
R39.1 Other difficulties with micturition
0.655 0.345 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.655 0.345 0.000
Z10 Routine general health check-up of defined subpopulation
0.655 0.345 0.000
Z90.3 Acquired absence of part of stomach
0.653 0.347 0.000
I24 Other acute ischaemic heart diseases
0.652 0.348 0.000
I44.6 Other and unspecified fascicular block
0.651 0.349 0.000
I44.5 Left posterior fascicular block
0.651 0.349 0.000
I44.4 Left anterior fascicular block
0.651 0.349 0.000
I44.3 Other and unspecified atrioventricular block
0.651 0.349 0.000
I44.1 Atrioventricular block, second degree
0.651 0.349 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.650 0.350 0.000
T79-T79 Certain early complications of trauma
0.650 0.350 0.000
T66-T78 Other and unspecified effects of external causes
0.650 0.350 0.000
T33-T35 Frostbite
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.650 0.350 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.650 0.350 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.650 0.350 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.650 0.350 0.000
T00-T07 Injuries involving multiple body regions
0.650 0.350 0.000
S90-S99 Injuries to the ankle and foot
0.650 0.350 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.650 0.350 0.000
S10-S19 Injuries to the neck
0.650 0.350 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.649 0.350 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.649 0.350 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.649 0.350 0.000
Chapter X Diseases of the respiratory system
0.649 0.351 0.000
I35.9 Aortic valve disorder, unspecified
0.648 0.351 0.000
I35.8 Other aortic valve disorders
0.648 0.351 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.648 0.351 0.000
K91.4 Colostomy and enterostomy malfunction
0.648 0.352 0.000
I60-I69 Cerebrovascular diseases
0.648 0.352 0.000
E00-E07 Disorders of thyroid gland
0.647 0.353 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.647 0.353 0.000
K59.8 Other specified functional intestinal disorders
0.647 0.353 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.645 0.355 0.000
K22.5 Diverticulum of oesophagus, acquired
0.645 0.355 0.000
K22.4 Dyskinesia of oesophagus
0.645 0.355 0.000
K22.3 Perforation of oesophagus
0.645 0.355 0.000
K22.0 Achalasia of cardia
0.645 0.355 0.000
N45 Orchitis and epididymitis
0.644 0.356 0.000
G20-G26 Extrapyramidal and movement disorders
0.643 0.357 0.000
Z98.8 Other specified postsurgical states
0.643 0.357 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.641 0.359 0.000
Z53.0 Procedure not carried out because of contraindication
0.641 0.359 0.000
H00 Hordeolum and chalazion
0.640 0.360 0.000
R36 Urethral discharge
0.640 0.360 0.000
R34 Anuria and oliguria
0.640 0.360 0.000
I15 Secondary hypertension
0.639 0.361 0.000
I13 Hypertensive heart and renal disease
0.639 0.361 0.000
I11 Hypertensive heart disease
0.639 0.361 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.639 0.361 0.000
N25-N29 Other disorders of kidney and ureter
0.639 0.361 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.638 0.362 0.000
L40-L45 Papulosquamous disorders
0.638 0.362 0.000
R50-R69 General symptoms and signs
0.638 0.362 0.000
N10-N16 Renal tubulo-interstitial diseases
0.638 0.362 0.000
K21 Gastro-oesophageal reflux disease
0.638 0.362 0.000
K59.0 Constipation
0.635 0.365 0.000
K30 Dyspepsia
0.635 0.365 0.000
E10.8 With unspecified complications
0.634 0.366 0.000
E10.7 With multiple complications
0.634 0.366 0.000
E10.6 With other specified complications
0.634 0.366 0.000
E10.5 With peripheral circulatory complications
0.634 0.366 0.000
E10.4 With neurological complications
0.634 0.366 0.000
E10.2 With renal complications
0.634 0.366 0.000
E10.1 With ketoacidosis
0.634 0.366 0.000
E10.0 With coma
0.634 0.366 0.000
K74 Fibrosis and cirrhosis of liver
0.634 0.366 0.000
H25.8 Other senile cataract
0.634 0.366 0.000
K61.3 Ischiorectal abscess
0.633 0.367 0.000
I85 Oesophageal varices
0.633 0.367 0.000
N99-N99 Other disorders of the genitourinary system
0.633 0.367 0.000
L60-L75 Disorders of skin appendages
0.633 0.367 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.633 0.367 0.000
S40-S49 Injuries to the shoulder and upper arm
0.632 0.368 0.000
I80 Phlebitis and thrombophlebitis
0.631 0.369 0.000
K26 Duodenal ulcer
0.631 0.369 0.000
K76 Other diseases of liver
0.631 0.369 0.000
R20.2 Paraesthesia of skin
0.630 0.370 0.000
Z48 Other surgical follow-up care
0.628 0.371 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.628 0.372 0.000
M65-M68 Disorders of synovium and tendon
0.628 0.372 0.000
N20-N23 Urolithiasis
0.627 0.373 0.000
Z96.1 Presence of intraocular lens
0.626 0.374 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.626 0.374 0.000
Z98.1 Arthrodesis status
0.626 0.374 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.625 0.375 0.000
I35.1 Aortic (valve) insufficiency
0.625 0.375 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.624 0.375 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.623 0.377 0.000
N00-N08 Glomerular diseases
0.623 0.377 0.000
Z46 Fitting and adjustment of other devices
0.622 0.377 0.000
L08 Other local infections of skin and subcutaneous tissue
0.622 0.378 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.622 0.378 0.000
E78.8 Other disorders of lipoprotein metabolism
0.622 0.378 0.000
E78.6 Lipoprotein deficiency
0.622 0.378 0.000
E78.4 Other hyperlipidaemia
0.622 0.378 0.000
E78.3 Hyperchylomicronaemia
0.622 0.378 0.000
E78.2 Mixed hyperlipidaemia
0.622 0.378 0.000
E78.1 Pure hyperglyceridaemia
0.622 0.378 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.621 0.379 0.000
Z03.8 Observation for other suspected diseases and conditions
0.620 0.380 0.000
R33 Retention of urine
0.620 0.380 0.000
I23 Certain current complications following acute myocardial infarction
0.620 0.380 0.000
I22 Subsequent myocardial infarction
0.620 0.380 0.000
I08 Multiple valve diseases
0.618 0.381 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.618 0.382 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.618 0.382 0.000
I45.1 Other and unspecified right bundle-branch block
0.618 0.382 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.617 0.383 0.000
R23 Other skin changes
0.617 0.383 0.000
H93 Other disorders of ear, not elsewhere classified
0.616 0.384 0.000
Z54 Convalescence
0.615 0.385 0.000
Z52 Donors of organs and tissues
0.615 0.385 0.000
Z49 Care involving dialysis
0.615 0.385 0.000
Z44 Fitting and adjustment of external prosthetic device
0.615 0.385 0.000
Z40 Prophylactic surgery
0.615 0.385 0.000
S70-S79 Injuries to the hip and thigh
0.614 0.385 0.000
Z93.9 Artificial opening status, unspecified
0.614 0.386 0.000
Z93.8 Other artificial opening status
0.614 0.386 0.000
Z93.6 Other artificial openings of urinary tract status
0.614 0.386 0.000
Z93.5 Cystostomy status
0.614 0.386 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.614 0.386 0.000
Z93.1 Gastrostomy status
0.614 0.386 0.000
Z93.0 Tracheostomy status
0.614 0.386 0.000
Z12 Special screening examination for neoplasms
0.614 0.386 0.000
K66 Other disorders of peritoneum
0.613 0.387 0.000
R30 Pain associated with micturition
0.611 0.388 0.000
H04 Disorders of lachrymal system
0.611 0.389 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.609 0.391 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.608 0.392 0.000
R26 Abnormalities of gait and mobility
0.608 0.392 0.000
H90 Conductive and sensorineural hearing loss
0.608 0.392 0.000
S62 Fracture at wrist and hand level
0.608 0.392 0.000
L82 Seborrhoeic keratosis
0.607 0.393 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.605 0.395 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.604 0.395 0.000
H02 Other disorders of eyelid
0.604 0.395 0.000
L90 Atrophic disorders of skin
0.604 0.396 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.603 0.397 0.000
Z51 Other medical care
0.602 0.398 0.000
I12 Hypertensive renal disease
0.601 0.399 0.000
M20-M25 Other joint disorders
0.600 0.400 0.000
S50-S59 Injuries to the elbow and forearm
0.600 0.400 0.000
K56.7 Ileus, unspecified
0.599 0.400 0.000
K56.4 Other impaction of intestine
0.599 0.400 0.000
K56.3 Gallstone ileus
0.599 0.400 0.000
K56.2 Volvulus
0.599 0.400 0.000
K56.1 Intussusception
0.599 0.400 0.000
K56.0 Paralytic ileus
0.599 0.400 0.000
K60.5 Anorectal fistula
0.599 0.401 0.000
K60.4 Rectal fistula
0.599 0.401 0.000
K60.1 Chronic anal fissure
0.599 0.401 0.000
K60.0 Acute anal fissure
0.599 0.401 0.000
Z03.4 Observation for suspected myocardial infarction
0.598 0.401 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.598 0.402 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.597 0.403 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.597 0.403 0.000
N32.0 Bladder-neck obstruction
0.597 0.403 0.000
Z41 Procedures for purposes other than remedying health state
0.595 0.405 0.000
K70 Alcoholic liver disease
0.594 0.405 0.000
E14.8 With unspecified complications
0.594 0.406 0.000
E14.7 With multiple complications
0.594 0.406 0.000
E14.6 With other specified complications
0.594 0.406 0.000
E14.5 With peripheral circulatory complications
0.594 0.406 0.000
E14.4 With neurological complications
0.594 0.406 0.000
E14.3 With ophthalmic complications
0.594 0.406 0.000
E14.2 Withrenal complications
0.594 0.406 0.000
E14.1 With ketoacidosis
0.594 0.406 0.000
E14.0 With coma
0.594 0.406 0.000
N30 Cystitis
0.594 0.406 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.594 0.406 0.000
I88 Nonspecific lymphadenitis
0.594 0.406 0.000
I87 Other disorders of veins
0.594 0.406 0.000
I86 Varicose veins of other sites
0.594 0.406 0.000
I82 Other venous embolism and thrombosis
0.594 0.406 0.000
I81 Portal vein thrombosis
0.594 0.406 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.594 0.406 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.594 0.406 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.594 0.406 0.000
M91-M94 Chondropathies
0.594 0.406 0.000
M86-M90 Other osteopathies
0.594 0.406 0.000
M60-M63 Disorders of muscles
0.594 0.406 0.000
M00-M03 Infectious arthropathies
0.594 0.406 0.000
N36 Other disorders of urethra
0.593 0.407 0.000
L05 Pilonidal cyst
0.593 0.407 0.000
L04 Acute lymphadenitis
0.593 0.407 0.000
L01 Impetigo
0.593 0.407 0.000
L00 Staphylococcal scalded skin syndrome
0.593 0.407 0.000
I25.2 Old myocardial infarction
0.592 0.408 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.592 0.408 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.592 0.408 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.592 0.408 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.592 0.408 0.000
Z82.3 Family history of stroke
0.592 0.408 0.000
Z82.2 Family history of deafness and hearing loss
0.592 0.408 0.000
Z82.1 Family history of blindness and visual loss
0.592 0.408 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.592 0.408 0.000
M05-M14 Inflammatory polyarthropathies
0.591 0.408 0.000
K50.9 Crohn's disease, unspecified
0.591 0.409 0.000
K62 Other diseases of anus and rectum
0.591 0.409 0.000
Z02.9 Examination for administrative purposes, unspecified
0.591 0.409 0.000
Z02.7 Issue of medical certificate
0.591 0.409 0.000
Z02.6 Examination for insurance purposes
0.591 0.409 0.000
Z02.5 Examination for participation in sport
0.591 0.409 0.000
Z02.4 Examination for driving licence
0.591 0.409 0.000
Z02.3 Examination for recruitment to armed forces
0.591 0.409 0.000
Z02.2 Examination for admission to residential institution
0.591 0.409 0.000
Z02.1 Pre-employment examination
0.591 0.409 0.000
Z02.0 Examination for admission to educational institution
0.591 0.409 0.000
M17 Gonarthrosis [arthrosis of knee]
0.591 0.409 0.000
R39.2 Extrarenal uraemia
0.590 0.409 0.000
R39.0 Extravasation of urine
0.590 0.409 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.590 0.410 0.000
K42 Umbilical hernia
0.590 0.410 0.000
H91 Other hearing loss
0.589 0.411 0.000
M40-M43 Deforming dorsopathies
0.588 0.411 0.000
Z00.0 General medical examination
0.588 0.411 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.588 0.412 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.588 0.412 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.588 0.412 0.000
Z03.3 Observation for suspected nervous system disorder
0.588 0.412 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.588 0.412 0.000
Z03.0 Observation for suspected tuberculosis
0.588 0.412 0.000
Chapter V Mental and behavioural disorders
0.588 0.412 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.587 0.413 0.000
E65-E68 Obesity and other hyperalimentation
0.586 0.413 0.000
Z47 Other orthopaedic follow-up care
0.586 0.414 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.584 0.416 0.000
K61.0 Anal abscess
0.584 0.416 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.584 0.416 0.000
H65 Nonsuppurative otitis media
0.584 0.416 0.000
G90-G99 Other disorders of the nervous system
0.583 0.417 0.000
K77 Liver disorders in diseases classified elsewhere
0.582 0.418 0.000
K75 Other inflammatory liver diseases
0.582 0.418 0.000
K73 Chronic hepatitis, not elsewhere classified
0.582 0.418 0.000
K72 Hepatic failure, not elsewhere classified
0.582 0.418 0.000
K71 Toxic liver disease
0.582 0.418 0.000
Z53.9 Procedure not carried out, unspecified reason
0.582 0.418 0.000
I95 Hypotension
0.582 0.418 0.000
T63 Toxic effect of contact with venomous animals
0.581 0.419 0.000
G70-G73 Diseases of myoneural junction and muscle
0.581 0.419 0.000
G30-G32 Other degenerative diseases of the nervous system
0.581 0.419 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.581 0.419 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.581 0.419 0.000
Z60 Problems related to social environment
0.580 0.420 0.000
K90.9 Intestinal malabsorption, unspecified
0.579 0.421 0.000
K90.8 Other intestinal malabsorption
0.579 0.421 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.579 0.421 0.000
K90.3 Pancreatic steatorrhoea
0.579 0.421 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.579 0.421 0.000
K90.1 Tropical sprue
0.579 0.421 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.579 0.421 0.000
K05 Gingivitis and periodontal diseases
0.577 0.423 0.000
N60-N64 Disorders of breast
0.576 0.424 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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