TreeWAS – Variant ID: rs16914920

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.998	0.002
S60-S69 Injuries to the wrist and hand	0.997	0.003
M70-M79 Other soft tissue disorders	0.996	0.004
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.993	0.007
O60-O75 Complications of labour and delivery	0.991	0.009
M20-M25 Other joint disorders	0.990	0.010
T81 Complications of procedures, not elsewhere classified	0.986	0.014
M05-M14 Inflammatory polyarthropathies	0.981	0.019
M25 Other joint disorders, not elsewhere classified	0.978	0.022
C15-C26 Malignant neoplasms of digestive organs	0.975	0.025
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.974	0.026
O48 Prolonged pregnancy	0.974	0.026
Chapter IV Endocrine, nutritional and metabolic diseases	0.968	0.032
M75 Shoulder lesions	0.964	0.036
S64 Injury of nerves at wrist and hand level	0.960	0.040
M79 Other soft tissue disorders, not elsewhere classified	0.958	0.042
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.954	0.046
O63 Long labour	0.947	0.053
M06 Other rheumatoid arthritis	0.942	0.058
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.939	0.061
C78.7 Secondary malignant neoplasm of liver	0.932	0.068
S64.4 Injury of digital nerve of other finger	0.929	0.071
O68 Labour and delivery complicated by foetal stress [distress]	0.921	0.079
M25.5 Pain in joint	0.920	0.080
Chapter VII Diseases of the eye and adnexa	0.920	0.080
M75.5 Bursitis of shoulder	0.915	0.085
M06.9 Rheumatoid arthritis, unspecified	0.914	0.086
O80-O84 Delivery	0.913	0.087
T81.4 Infection following a procedure, not elsewhere classified	0.910	0.090
C79 Secondary malignant neoplasm of other sites	0.909	0.091
C78.0 Secondary malignant neoplasm of lung	0.908	0.092
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.908	0.092
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.908	0.092
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.906	0.094
C18 Malignant neoplasm of colon	0.902	0.098
M79.8 Other specified soft tissue disorders	0.901	0.099
C78.2 Secondary malignant neoplasm of pleura	0.895	0.105
S66 Injury of muscle and tendon at wrist and hand level	0.891	0.109
O85-O92 Complications predominantly related to the puerperium	0.889	0.111
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.886	0.114
E20-E35 Disorders of other endocrine glands	0.882	0.118
Chapter XIV Diseases of the genitourinary system	0.869	0.131
C79.8 Secondary malignant neoplasm of other specified sites	0.867	0.133
O42 Premature rupture of membranes	0.861	0.139
O47 False labour	0.861	0.139
T86 Failure and rejection of transplanted organs and tissues	0.859	0.141
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.856	0.144
S00-S09 Injuries to the head	0.853	0.147
M25.51 Pain in joint (Shoulder region)	0.853	0.147
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.853	0.147
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.852	0.148
Chapter I Certain infectious and parasitic diseases	0.851	0.149
M05 Seropositive rheumatoid arthritis	0.847	0.153
S61 Open wound of wrist and hand	0.845	0.155
O00-O08 Pregnancy with abortive outcome	0.837	0.163
M25.50 Pain in joint (Multiple sites)	0.837	0.163
M25.9 Joint disorder, unspecified	0.836	0.163
O63.9 Long labour, unspecified	0.834	0.166
M77 Other enthesopathies	0.831	0.169
N10-N16 Renal tubulo-interstitial diseases	0.828	0.172
M31 Other necrotising vasculopathies	0.826	0.174
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.825	0.175
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.824	0.176
M24 Other specific joint derangements	0.824	0.176
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.822	0.178
M25.8 Other specified joint disorders	0.821	0.179
M79.86 Other specified soft tissue disorders (Lower leg)	0.821	0.179
M25.52 Pain in joint (Upper arm)	0.820	0.180
O20-O29 Other maternal disorders predominantly related to pregnancy	0.818	0.182
N60-N64 Disorders of breast	0.817	0.183
O82 Single delivery by Caesarean section	0.815	0.185
M07 Psoriatic and enteropathic arthropathies	0.815	0.185
O63.0 Prolonged first stage (of labour)	0.812	0.188
C20 Malignant neoplasm of rectum	0.811	0.189
M65-M68 Disorders of synovium and tendon	0.809	0.191
S20-S29 Injuries to the thorax	0.808	0.192
N00-N08 Glomerular diseases	0.808	0.192
O64 Obstructed labour due to malposition and malpresentation of foetus	0.807	0.193
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.804	0.196
H25-H28 Disorders of lens	0.804	0.196
C19 Malignant neoplasm of rectosigmoid junction	0.803	0.197
E10-E14 Diabetes mellitus	0.802	0.198
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.801	0.199
H55-H59 Other disorders of eye and adnexa	0.800	0.199
C77.1 Intrathoracic lymph nodes	0.800	0.200
O63.1 Prolonged second stage (of labour)	0.800	0.200
C18.7 Sigmoid colon	0.798	0.202
M10 Gout	0.797	0.202
M23 Internal derangement of knee	0.797	0.203
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.796	0.204
O94-O99 Other obstetric conditions, not elsewhere classified	0.795	0.205
Chapter VIII Diseases of the ear and mastoid process	0.795	0.205
T81.8 Other complications of procedures, not elsewhere classified	0.795	0.205
M75.3 Calcific tendinitis of shoulder	0.793	0.207
C16 Malignant neoplasm of stomach	0.792	0.208
N13 Obstructive and reflux uropathy	0.791	0.209
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.790	0.210
M25.4 Effusion of joint	0.789	0.211
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.788	0.212
O32 Maternal care for known or suspected malpresentation of foetus	0.787	0.213
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.786	0.214
M79.7 Fibromyalgia	0.784	0.216
C51-C58 Malignant neoplasms of female genital organs	0.781	0.219
M75.4 Impingement syndrome of shoulder	0.781	0.219
C60-C63 Malignant neoplasms of male genital organs	0.780	0.220
S68 Traumatic amputation of wrist and hand	0.779	0.221
M79.1 Myalgia	0.774	0.225
E70-E90 Metabolic disorders	0.773	0.227
S40-S49 Injuries to the shoulder and upper arm	0.771	0.229
T20-T25 Burns and corrosions of external body surface, specified by site	0.771	0.229
C18.6 Descending colon	0.771	0.229
S00 Superficial injury of head	0.770	0.230
E16 Other disorders of pancreatic internal secretion	0.770	0.230
D37-D48 Neoplasms of uncertain or unknown behaviour	0.770	0.230
O81 Single delivery by forceps and vacuum extractor	0.769	0.231
M76 Enthesopathies of lower limb, excluding foot	0.769	0.231
C77.9 Lymph node, unspecified	0.767	0.233
M21 Other acquired deformities of limbs	0.766	0.233
O86 Other puerperal infections	0.764	0.235
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.764	0.236
E87 Other disorders of fluid, electrolyte and acid-base balance	0.764	0.236
T93 Sequelae of injuries of lower limb	0.763	0.237
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.762	0.238
M79.84 Other specified soft tissue disorders (Hand)	0.757	0.243
O43 Placental disorders	0.756	0.243
T88 Other complications of surgical and medical care, not elsewhere classified	0.756	0.244
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.756	0.244
C77.5 Intrapelvic lymph nodes	0.755	0.245
B15-B19 Viral hepatitis	0.754	0.246
N61 Inflammatory disorders of breast	0.754	0.246
M75.9 Shoulder lesion, unspecified	0.753	0.247
C15 Malignant neoplasm of oesophagus	0.752	0.247
O41 Other disorders of amniotic fluid and membranes	0.752	0.248
Chapter V Mental and behavioural disorders	0.751	0.249
S67 Crushing injury of wrist and hand	0.751	0.249
M05.9 Seropositive rheumatoid arthritis, unspecified	0.751	0.249
M25.6 Stiffness of joint, not elsewhere classified	0.747	0.252
O47.1 False labour at or after 37 completed weeks of gestation	0.747	0.253
O03 Spontaneous abortion	0.747	0.253
O82.1 Delivery by emergency Caesarean section	0.745	0.255
O69 Labour and delivery complicated by umbilical cord complications	0.745	0.255
C79.7 Secondary malignant neoplasm of adrenal gland	0.744	0.256
M70 Soft tissue disorders related to use, overuse and pressure	0.743	0.257
O66 Other obstructed labour	0.742	0.258
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.740	0.260
M22 Disorders of patella	0.740	0.260
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.739	0.261
S90-S99 Injuries to the ankle and foot	0.737	0.263
S69 Other and unspecified injuries of wrist and hand	0.737	0.263
C77.4 Inguinal and lower limb lymph nodes	0.736	0.264
T90 Sequelae of injuries of head	0.735	0.265
M25.96 Joint disorder, unspecified (Lower leg)	0.735	0.265
T92 Sequelae of injuries of upper limb	0.733	0.267
O72 Postpartum haemorrhage	0.732	0.268
M71 Other bursopathies	0.731	0.269
C18.1 Appendix	0.730	0.270
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.729	0.271
N20-N23 Urolithiasis	0.729	0.271
O87 Venous complications in the puerperium	0.728	0.271
M75.1 Rotator cuff syndrome	0.728	0.272
M25.7 Osteophyte	0.728	0.272
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.728	0.272
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.728	0.272
T80 Complications following infusion, transfusion and therapeutic injection	0.728	0.272
E27 Other disorders of adrenal gland	0.726	0.274
C71 Malignant neoplasm of brain	0.725	0.274
C18.4 Transverse colon	0.724	0.276
H53-H54 Visual disturbances and blindness	0.723	0.277
N60 Benign mammary dysplasia	0.723	0.277
S64.3 Injury of digital nerve of thumb	0.723	0.277
S61.8 Open wound of other parts of wrist and hand	0.722	0.278
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.720	0.280
M91-M94 Chondropathies	0.720	0.280
O46 Antepartum haemorrhage, not elsewhere classified	0.719	0.280
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.719	0.280
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
M79.0 Rheumatism, unspecified	0.717	0.283
H10-H13 Disorders of conjunctiva	0.716	0.284
M23.2 Derangement of meniscus due to old tear or injury	0.716	0.284
C78.4 Secondary malignant neoplasm of small intestine	0.716	0.284
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.716	0.284
C78.1 Secondary malignant neoplasm of mediastinum	0.716	0.284
T87 Complications peculiar to reattachment and amputation	0.715	0.284
S65 Injury of blood vessels at wrist and hand level	0.715	0.285
M73 Soft tissue disorders in diseases classified elsewhere	0.714	0.286
T86.0 Bone-marrow transplant rejection	0.714	0.286
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.714	0.286
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.713	0.287
C77.2 Intra-abdominal lymph nodes	0.713	0.287
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.713	0.287
O45 Premature separation of placenta [abruptio placentae]	0.712	0.288
O44 Placenta praevia	0.712	0.288
O35 Maternal care for known or suspected foetal abnormality and damage	0.712	0.288
O33 Maternal care for known or suspected disproportion	0.712	0.288
O31 Complications specific to multiple gestation	0.712	0.288
O40 Polyhydramnios	0.712	0.288
S60 Superficial injury of wrist and hand	0.712	0.288
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.711	0.289
E16.2 Hypoglycaemia, unspecified	0.711	0.289
O74 Complications of anaesthesia during labour and delivery	0.710	0.290
O71 Other obstetric trauma	0.710	0.290
O65 Obstructed labour due to maternal pelvic abnormality	0.710	0.290
O62 Abnormalities of forces of labour	0.710	0.290
O61 Failed induction of labour	0.710	0.290
O60 Preterm delivery	0.710	0.290
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.710	0.290
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.710	0.290
M34 Systemic sclerosis	0.710	0.290
M33 Dermatopolymyositis	0.710	0.290
M32 Systemic lupus erythematosus	0.710	0.290
M30 Polyarteritis nodosa and related conditions	0.710	0.290
E87.2 Acidosis	0.708	0.292
M31.6 Other giant cell arteritis	0.708	0.292
E00-E07 Disorders of thyroid gland	0.707	0.293
H46-H48 Disorders of optic nerve and visual pathways	0.707	0.293
T81.9 Unspecified complication of procedure	0.707	0.293
T81.7 Vascular complications following a procedure, not elsewhere classified	0.707	0.293
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.707	0.293
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.707	0.293
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.706	0.294
M14 Arthropathies in other diseases classified elsewhere	0.704	0.296
M12 Other specific arthropathies	0.704	0.296
M09 Juvenile arthritis in diseases classified elsewhere	0.704	0.296
M08 Juvenile arthritis	0.704	0.296
M11 Other crystal arthropathies	0.702	0.298
M80-M85 Disorders of bone density and structure	0.702	0.298
M25.3 Other instability of joint	0.701	0.299
M25.2 Flail joint	0.701	0.299
M25.1 Fistula of joint	0.701	0.299
M25.0 Haemarthrosis	0.701	0.299
O36 Maternal care for other known or suspected foetal problems	0.700	0.299
D10-D36 Benign neoplasms	0.700	0.300
S63.6 Sprain and strain of finger(s)	0.700	0.300
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.700	0.300
C26 Malignant neoplasm of other and ill-defined digestive organs	0.699	0.301
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.699	0.301
C21 Malignant neoplasm of anus and anal canal	0.699	0.301
C17 Malignant neoplasm of small intestine	0.699	0.301
C23 Malignant neoplasm of gallbladder	0.699	0.301
E11 Non-insulin-dependent diabetes mellitus	0.698	0.302
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.697	0.303
T15-T19 Effects of foreign body entering through natural orifice	0.696	0.303
A00-A09 Intestinal infectious diseases	0.696	0.303
M07.3 Other psoriatic arthropathies	0.695	0.305
E40-E46 Malnutrition	0.694	0.306
M25.54 Pain in joint (Hand)	0.694	0.306
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.692	0.308
T86.8 Failure and rejection of other transplanted organs and tissues	0.691	0.309
C77.8 Lymph nodes of multiple regions	0.691	0.309
M75.8 Other shoulder lesions	0.691	0.309
M75.2 Bicipital tendinitis	0.691	0.309
M86-M90 Other osteopathies	0.690	0.310
N03 Chronic nephritic syndrome	0.689	0.311
S64.9 Injury of unspecified nerve at wrist and hand level	0.688	0.312
S64.8 Injury of other nerves at wrist and hand level	0.688	0.312
S64.7 Injury of multiple nerves at wrist and hand level	0.688	0.312
S64.2 Injury of radial nerve at wrist and hand level	0.688	0.312
S64.1 Injury of median nerve at wrist and hand level	0.688	0.312
S64.0 Injury of ulnar nerve at wrist and hand level	0.688	0.312
S01 Open wound of head	0.688	0.312
M79.9 Soft tissue disorder, unspecified	0.687	0.313
M79.5 Residual foreign body in soft tissue	0.687	0.313
M79.4 Hypertrophy of (infrapatellar) fat pad	0.687	0.313
M79.3 Panniculitis, unspecified	0.687	0.313
M79.2 Neuralgia and neuritis, unspecified	0.687	0.313
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.686	0.314
D00-D09 In situ neoplasms	0.686	0.314
S06 Intracranial injury	0.685	0.315
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.685	0.315
M25.57 Pain in joint (Ankle and foot)	0.685	0.315
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.685	0.315
O75 Other complications of labour and delivery, not elsewhere classified	0.685	0.315
E28 Ovarian dysfunction	0.684	0.316
Chapter XXII Codes for special purposes	0.684	0.316
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.683	0.317
E50-E64 Other nutritional deficiencies	0.681	0.319
N02 Recurrent and persistent haematuria	0.680	0.320
O63.2 Delayed delivery of second twin, triplet, etc.	0.679	0.321
F30-F39 Mood [affective] disorders	0.678	0.322
O73 Retained placenta and membranes, without haemorrhage	0.678	0.322
N13.8 Other obstructive and reflux uropathy	0.678	0.322
O42.9 Premature rupture of membranes, unspecified	0.677	0.323
H30-H36 Disorders of choroid and retina	0.677	0.323
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.677	0.323
N20 Calculus of kidney and ureter	0.677	0.323
E24 Cushing's syndrome	0.677	0.323
M25.86 Other specified joint disorders (Lower leg)	0.676	0.324
Chapter XII Diseases of the skin and subcutaneous tissue	0.676	0.324
M06.8 Other specified rheumatoid arthritis	0.675	0.325
M06.4 Inflammatory polyarthropathy	0.675	0.325
M06.3 Rheumatoid nodule	0.675	0.325
M06.2 Rheumatoid bursitis	0.675	0.325
M06.1 Adult-onset Still's disease	0.675	0.325
M06.0 Seronegative rheumatoid arthritis	0.675	0.325
M23.4 Loose body in knee	0.675	0.325
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.675	0.325
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.675	0.325
M24.5 Contracture of joint	0.675	0.325
S61.7 Multiple open wounds of wrist and hand	0.674	0.325
H26 Other cataract	0.674	0.326
S00.0 Superficial injury of scalp	0.674	0.326
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.673	0.327
C77.0 Lymph nodes of head, face and neck	0.670	0.330
T66-T78 Other and unspecified effects of external causes	0.670	0.330
B18 Chronic viral hepatitis	0.669	0.331
C79.2 Secondary malignant neoplasm of skin	0.667	0.333
A50-A64 Infections with a predominantly sexual mode of transmission	0.667	0.333
O81.4 Vacuum extractor delivery	0.666	0.333
N11 Chronic tubulo-interstitial nephritis	0.666	0.334
M10.9 Gout, unspecified	0.666	0.334
T93.2 Sequelae of other fractures of lower limb	0.664	0.336
M35 Other systemic involvement of connective tissue	0.663	0.336
M79.70 Fibromyalgia (Multiple sites)	0.663	0.337
O03.9 Complete or unspecified, without complication	0.663	0.337
T85 Complications of other internal prosthetic devices, implants and grafts	0.662	0.338
C43-C44 Melanoma and other malignant neoplasms of skin	0.662	0.338
T82.1 Mechanical complication of cardiac electronic device	0.661	0.338
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.660	0.339
E23 Hypofunction and other disorders of pituitary gland	0.660	0.340
M25.59 Pain in joint (Site unspecified)	0.659	0.340
M25.58 Pain in joint (Other)	0.659	0.340
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.659	0.341
O47.9 False labour, unspecified	0.659	0.341
C18.2 Ascending colon	0.659	0.341
D37.5 Rectum	0.657	0.343
O30 Multiple gestation	0.656	0.344
A30-A49 Other bacterial diseases	0.656	0.344
M06.98 Rheumatoid arthritis, unspecified (Other)	0.655	0.345
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.655	0.345
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.655	0.345
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.655	0.345
C18.3 Hepatic flexure	0.655	0.345
O84 Multiple delivery	0.654	0.345
O83 Other assisted single delivery	0.654	0.345
N08 Glomerular disorders in diseases classified elsewhere	0.653	0.347
M24.8 Other specific joint derangements, not elsewhere classified	0.653	0.347
E10 Insulin-dependent diabetes mellitus	0.653	0.347
C69 Malignant neoplasm of eye and adnexa	0.653	0.347
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.653	0.347
M77.4 Metatarsalgia	0.652	0.348
C79.6 Secondary malignant neoplasm of ovary	0.652	0.348
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.652	0.348
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.652	0.348
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.652	0.348
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.651	0.349
T98 Sequelae of other and unspecified effects of external causes	0.651	0.349
T95 Sequelae of burns, corrosions and frostbite	0.651	0.349
T94 Sequelae of injuries involving multiple and unspecified body regions	0.651	0.349
T91 Sequelae of injuries of neck and trunk	0.651	0.349
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.651	0.349
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.651	0.349
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.651	0.349
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.651	0.349
T82.4 Mechanical complication of vascular dialysis catheter	0.651	0.349
T82.3 Mechanical complication of other vascular grafts	0.651	0.349
T82.0 Mechanical complication of heart valve prosthesis	0.651	0.349
E29 Testicular dysfunction	0.650	0.350
O23 Infections of genito-urinary tract in pregnancy	0.650	0.350
S63.1 Dislocation finger	0.649	0.350
S63.7 Sprain and strain of other and unspecified parts of hand	0.649	0.350
S63.5 Sprain and strain of wrist	0.649	0.350
S63.3 Traumatic rupture of ligament of wrist and carpus	0.649	0.350
S63.2 Multiple dislocations of fingers	0.649	0.350
S63.0 Dislocation of wrist	0.649	0.350
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.649	0.351
E22 Hyperfunction of pituitary gland	0.648	0.352
Q38-Q45 Other congenital malformations of the digestive system	0.647	0.352
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.647	0.353
C18.8 Overlapping lesion of colon	0.647	0.353
C18.5 Splenic flexure	0.647	0.353
M79.89 Other specified soft tissue disorders (Site unspecified)	0.646	0.354
M79.88 Other specified soft tissue disorders (Other)	0.646	0.354
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.646	0.354
M79.83 Other specified soft tissue disorders (Forearm)	0.646	0.354
M79.82 Other specified soft tissue disorders (Upper arm)	0.646	0.354
M79.81 Other specified soft tissue disorders (Shoulder region)	0.646	0.354
M79.80 Other specified soft tissue disorders (Multiple sites)	0.646	0.354
S22 Fracture of rib(s), sternum and thoracic spine	0.646	0.354
O67.9 Intrapartum haemorrhage, unspecified	0.646	0.354
M77.1 Lateral epicondylitis	0.645	0.355
F33 Recurrent depressive disorder	0.644	0.356
H57 Other disorders of eye and adnexa	0.644	0.356
S27 Injury of other and unspecified intrathoracic organs	0.644	0.356
M79.19 Myalgia (Site unspecified)	0.643	0.357
H80-H83 Diseases of inner ear	0.643	0.357
E87.1 Hypo-osmolality and hyponatraemia	0.643	0.357
M25.77 Osteophyte (Ankle and foot)	0.642	0.358
M25.84 Other specified joint disorders (Hand)	0.642	0.358
C77.3 Axillary and upper limb lymph nodes	0.642	0.358
A80-A89 Viral infections of the central nervous system	0.641	0.359
E87.6 Hypokalaemia	0.641	0.359
C80 Malignant neoplasm without specification of site	0.641	0.359
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.641	0.359
Q50-Q56 Congenital malformations of genital organs	0.641	0.359
S70-S79 Injuries to the hip and thigh	0.639	0.360
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.639	0.361
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.639	0.361
S66.8 Injury of other muscles and tendons at wrist and hand level	0.639	0.361
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.639	0.361
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.639	0.361
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.639	0.361
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.639	0.361
O86.0 Infection of obstetric surgical wound	0.638	0.362
O92 Other disorders of breast and lactation associated with childbirth	0.637	0.362
O91 Infections of breast associated with childbirth	0.637	0.362
O90 Complications of the puerperium, not elsewhere classified	0.637	0.362
O89 Complications of anaesthesia during the puerperium	0.637	0.362
O88 Obstetric embolism	0.637	0.362
O85 Puerperal sepsis	0.637	0.362
H90-H95 Other disorders of ear	0.637	0.363
S00.8 Superficial injury of other parts of head	0.636	0.363
Q80-Q89 Other congenital malformations	0.635	0.364
M65 Synovitis and tenosynovitis	0.635	0.365
M77.9 Enthesopathy, unspecified	0.634	0.366
N20.1 Calculus of ureter	0.634	0.366
L40-L45 Papulosquamous disorders	0.634	0.366
S61.0 Open wound of finger(s) without damage to nail	0.633	0.367
H25 Senile cataract	0.633	0.367
O02 Other abnormal products of conception	0.633	0.367
E35 Disorders of endocrine glands in diseases classified elsewhere	0.632	0.368
E34 Other endocrine disorders	0.632	0.368
E32 Diseases of thymus	0.632	0.368
E31 Polyglandular dysfunction	0.632	0.368
E30 Disorders of puberty, not elsewhere classified	0.632	0.368
E26 Hyperaldosteronism	0.632	0.368
E25 Adrenogenital disorders	0.632	0.368
E20 Hypoparathyroidism	0.632	0.368
M21.0 Valgus deformity, not elsewhere classified	0.631	0.369
C16.9 Stomach, unspecified	0.630	0.369
E87.0 Hyperosmolality and hypernatraemia	0.630	0.370
M66 Spontaneous rupture of synovium and tendon	0.629	0.371
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.629	0.371
S62 Fracture at wrist and hand level	0.628	0.372
Chapter XX External causes of morbidity and mortality	0.628	0.372
B25-B34 Other viral diseases	0.628	0.372
E07 Other disorders of thyroid	0.628	0.372
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.627	0.373
D17 Benign lipomatous neoplasm	0.626	0.374
C15.9 Oesophagus, unspecified	0.624	0.376
E11.3 With ophthalmic complications	0.624	0.376
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.623	0.377
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.623	0.377
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.623	0.377
O24 Diabetes mellitus in pregnancy	0.622	0.377
O20 Haemorrhage in early pregnancy	0.622	0.378
M25.47 Effusion of joint (Ankle and foot)	0.621	0.379
M79.6 Pain in limb	0.621	0.379
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.620	0.380
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.619	0.381
O42.2 Premature rupture of membranes, labour delayed by therapy	0.617	0.382
O47.0 False labour before 37 completed weeks of gestation	0.617	0.382
E80 Disorders of porphyrin and bilirubin metabolism	0.617	0.383
O80 Single spontaneous delivery	0.616	0.384
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.616	0.384
T86.4 Liver transplant failure and rejection	0.616	0.384
T86.3 Heart-lung transplant failure and rejection	0.616	0.384
T86.2 Heart transplant failure and rejection	0.616	0.384
T86.1 Kidney transplant failure and rejection	0.616	0.384
D11 Benign neoplasm of major salivary glands	0.615	0.385
E27.1 Primary adrenocortical insufficiency	0.614	0.386
C61 Malignant neoplasm of prostate	0.614	0.386
C55 Malignant neoplasm of uterus, part unspecified	0.614	0.386
M45-M49 Spondylopathies	0.614	0.386
C25 Malignant neoplasm of pancreas	0.614	0.386
M99 Biomechanical lesions, not elsewhere classified	0.614	0.386
O87.2 Haemorrhoids in the puerperium	0.613	0.387
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.612	0.388
S08 Traumatic amputation of part of head	0.612	0.388
S07 Crushing injury of head	0.612	0.388
S05 Injury of eye and orbit	0.612	0.388
S04 Injury of cranial nerves	0.612	0.388
S03 Dislocation, sprain and strain of joints and ligaments of head	0.612	0.388
O86.4 Pyrexia of unknown origin following delivery	0.612	0.388
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.611	0.389
C70 Malignant neoplasm of meninges	0.611	0.389
C16.0 Cardia	0.611	0.389
T83.1 Mechanical complication of other urinary devices and implants	0.611	0.389
E15 Nondiabetic hypoglycaemic coma	0.611	0.389
F80-F89 Disorders of psychological development	0.611	0.389
L40 Psoriasis	0.611	0.389
B99-B99 Other infectious diseases	0.610	0.390

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations