TreeWAS – Variant ID: rs16950650

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.502	0.498
Chapter II Neoplasms	0.502	0.498
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.501	0.499
L72 Follicular cysts of skin and subcutaneous tissue	0.499	0.501
L60-L75 Disorders of skin appendages	0.498	0.502
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.497	0.503
Chapter XII Diseases of the skin and subcutaneous tissue	0.497	0.503
L72.1 Trichilemmal cyst	0.494	0.506
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.477	0.523
C15-C26 Malignant neoplasms of digestive organs	0.477	0.523
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.468	0.532
Chapter X Diseases of the respiratory system	0.462	0.538
J40-J47 Chronic lower respiratory diseases	0.461	0.539
J44 Other chronic obstructive pulmonary disease	0.455	0.545
M80-M85 Disorders of bone density and structure	0.452	0.548
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.448	0.552
D10-D36 Benign neoplasms	0.448	0.552
T85 Complications of other internal prosthetic devices, implants and grafts	0.445	0.555
C16 Malignant neoplasm of stomach	0.442	0.558
S80-S89 Injuries to the knee and lower leg	0.440	0.560
M05-M14 Inflammatory polyarthropathies	0.439	0.561
L72.0 Epidermal cyst	0.432	0.568
C15 Malignant neoplasm of oesophagus	0.432	0.568
S50-S59 Injuries to the elbow and forearm	0.431	0.569
C77.2 Intra-abdominal lymph nodes	0.430	0.570
D00-D09 In situ neoplasms	0.429	0.571
J44.9 Chronic obstructive pulmonary disease, unspecified	0.428	0.572
M70-M79 Other soft tissue disorders	0.423	0.577
L20-L30 Dermatitis and eczema	0.423	0.577
M50-M54 Other dorsopathies	0.423	0.577
Chapter XXII Codes for special purposes	0.422	0.578
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.421	0.579
D23 Other benign neoplasms of skin	0.418	0.582
C19 Malignant neoplasm of rectosigmoid junction	0.417	0.583
J43 Emphysema	0.416	0.584
S10-S19 Injuries to the neck	0.415	0.585
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.413	0.587
C16.0 Cardia	0.413	0.587
S90-S99 Injuries to the ankle and foot	0.410	0.590
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.409	0.591
D25 Leiomyoma of uterus	0.409	0.591
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.408	0.592
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.406	0.594
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.404	0.596
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.403	0.597
Chapter XX External causes of morbidity and mortality	0.398	0.602
S20-S29 Injuries to the thorax	0.396	0.603
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.396	0.604
L60 Nail disorders	0.393	0.607
M65-M68 Disorders of synovium and tendon	0.392	0.608
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.389	0.611
M20-M25 Other joint disorders	0.388	0.612
D05 Carcinoma in situ of breast	0.387	0.613
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.387	0.613
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.385	0.615
J43.9 Emphysema, unspecified	0.385	0.615
D23.7 Skin of lower limb, including hip	0.384	0.616
M75 Shoulder lesions	0.384	0.616
Chapter V Mental and behavioural disorders	0.382	0.618
C15.5 Lower third of oesophagus	0.382	0.618
L50-L54 Urticaria and erythema	0.382	0.618
D50-D53 Nutritional anaemias	0.381	0.619
M06 Other rheumatoid arthritis	0.380	0.620
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.380	0.620
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.379	0.620
M84 Disorders of continuity of bone	0.378	0.622
S70-S79 Injuries to the hip and thigh	0.377	0.622
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.376	0.624
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.375	0.624
T85.4 Mechanical complication of breast prosthesis and implant	0.375	0.625
M81 Osteoporosis without pathological fracture	0.374	0.625
D37-D48 Neoplasms of uncertain or unknown behaviour	0.374	0.626
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.373	0.627
M54 Dorsalgia	0.373	0.627
M40-M43 Deforming dorsopathies	0.372	0.628
D05.1 Intraductal carcinoma in situ	0.370	0.630
C79 Secondary malignant neoplasm of other sites	0.367	0.633
J47 Bronchiectasis	0.367	0.633
D23.0 Skin of lip	0.366	0.634
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.366	0.634
D25.9 Leiomyoma of uterus, unspecified	0.366	0.634
T66-T78 Other and unspecified effects of external causes	0.365	0.635
T88 Other complications of surgical and medical care, not elsewhere classified	0.363	0.637
S80 Superficial injury of lower leg	0.361	0.639
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.360	0.640
C60-C63 Malignant neoplasms of male genital organs	0.360	0.640
Chapter XVI Certain conditions originating in the perinatal period	0.360	0.640
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.360	0.640
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.360	0.640
C40-C41 Malignant neoplasms of bone and articular cartilage	0.360	0.640
S51 Open wound of forearm	0.360	0.640
T79-T79 Certain early complications of trauma	0.359	0.641
T33-T35 Frostbite	0.359	0.641
T26-T28 Burns and corrosions confined to eye and internal organs	0.359	0.641
T20-T25 Burns and corrosions of external body surface, specified by site	0.359	0.641
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.359	0.641
T00-T07 Injuries involving multiple body regions	0.359	0.641
T15-T19 Effects of foreign body entering through natural orifice	0.359	0.641
M11 Other crystal arthropathies	0.359	0.641
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.358	0.642
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.358	0.642
L72.2 Steatocystoma multiplex	0.358	0.642
D36 Benign neoplasm of other and unspecified sites	0.358	0.642
L75 Apocrine sweat disorders	0.357	0.643
L74 Eccrine sweat disorders	0.357	0.643
L73 Other follicular disorders	0.357	0.643
L70 Acne	0.357	0.643
L68 Hypertrichosis	0.357	0.643
L67 Hair colour and hair shaft abnormalities	0.357	0.643
L66 Cicatricial alopecia [scarring hair loss]	0.357	0.643
L65 Other nonscarring hair loss	0.357	0.643
L64 Androgenic alopecia	0.357	0.643
L63 Alopecia areata	0.357	0.643
L62 Nail disorders in diseases classified elsewhere	0.357	0.643
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.357	0.643
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.356	0.644
M91-M94 Chondropathies	0.356	0.644
M86-M90 Other osteopathies	0.356	0.644
M60-M63 Disorders of muscles	0.356	0.644
M00-M03 Infectious arthropathies	0.356	0.644
L10-L14 Bullous disorders	0.356	0.644
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.355	0.644
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.355	0.645
L71 Rosacea	0.353	0.646
J30-J39 Other diseases of upper respiratory tract	0.351	0.648
J60-J70 Lung diseases due to external agents	0.351	0.649
C15.9 Oesophagus, unspecified	0.350	0.649
C77.5 Intrapelvic lymph nodes	0.350	0.650
L30 Other dermatitis	0.350	0.650
J42 Unspecified chronic bronchitis	0.350	0.650
M50 Cervical disk disorders	0.350	0.650
C77.0 Lymph nodes of head, face and neck	0.347	0.652
D32 Benign neoplasm of meninges	0.347	0.653
S52 Fracture of forearm	0.346	0.653
D34 Benign neoplasm of thyroid gland	0.346	0.654
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.345	0.654
C80 Malignant neoplasm without specification of site	0.345	0.655
L29 Pruritus	0.344	0.656
M85 Other disorders of bone density and structure	0.343	0.657
M80 Osteoporosis with pathological fracture	0.343	0.657
C26 Malignant neoplasm of other and ill-defined digestive organs	0.342	0.658
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.342	0.658
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.342	0.658
C21 Malignant neoplasm of anus and anal canal	0.342	0.658
C17 Malignant neoplasm of small intestine	0.342	0.658
C23 Malignant neoplasm of gallbladder	0.342	0.658
C76 Malignant neoplasm of other and ill-defined sites	0.342	0.658
D25.0 Submucous leiomyoma of uterus	0.342	0.658
D13.2 Duodenum	0.341	0.659
C77.1 Intrathoracic lymph nodes	0.341	0.659
M54.5 Low back pain	0.341	0.659
L40-L45 Papulosquamous disorders	0.341	0.659
D26 Other benign neoplasms of uterus	0.341	0.659
D13.0 Oesophagus	0.340	0.660
D10 Benign neoplasm of mouth and pharynx	0.340	0.660
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.339	0.660
J09-J18 Influenza and pneumonia	0.339	0.661
M06.9 Rheumatoid arthritis, unspecified	0.339	0.661
D50 Iron deficiency anaemia	0.338	0.662
C51-C58 Malignant neoplasms of female genital organs	0.336	0.664
C16.9 Stomach, unspecified	0.336	0.664
S92 Fracture of foot, except ankle	0.336	0.664
S19 Other and unspecified injuries of neck	0.335	0.664
T87 Complications peculiar to reattachment and amputation	0.335	0.664
T86 Failure and rejection of transplanted organs and tissues	0.335	0.664
T80 Complications following infusion, transfusion and therapeutic injection	0.335	0.664
D35 Benign neoplasm of other and unspecified endocrine glands	0.335	0.665
C77.4 Inguinal and lower limb lymph nodes	0.334	0.666
C20 Malignant neoplasm of rectum	0.334	0.666
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.331	0.669
D23.2 Skin of ear and external auricular canal	0.331	0.669
J41 Simple and mucopurulent chronic bronchitis	0.330	0.670
J46 Status asthmaticus	0.330	0.670
M75.4 Impingement syndrome of shoulder	0.330	0.670
C78.2 Secondary malignant neoplasm of pleura	0.328	0.672
M70 Soft tissue disorders related to use, overuse and pressure	0.326	0.674
M75.3 Calcific tendinitis of shoulder	0.326	0.674
S89 Other and unspecified injuries of lower leg	0.326	0.674
S60-S69 Injuries to the wrist and hand	0.326	0.674
D13.1 Stomach	0.326	0.674
M77 Other enthesopathies	0.326	0.674
M84.1 Nonunion of fracture [pseudarthrosis]	0.325	0.675
S12 Fracture of neck	0.324	0.676
C64-C68 Malignant neoplasms of urinary tract	0.324	0.676
M83 Adult osteomalacia	0.324	0.676
M82 Osteoporosis in diseases classified elsewhere	0.324	0.676
S32 Fracture of lumbar spine and pelvis	0.323	0.677
Chapter I Certain infectious and parasitic diseases	0.322	0.678
S81 Open wound of lower leg	0.322	0.678
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.322	0.678
C77.8 Lymph nodes of multiple regions	0.321	0.679
M54.1 Radiculopathy	0.321	0.679
D31 Benign neoplasm of eye and adnexa	0.321	0.679
D30 Benign neoplasm of urinary organs	0.321	0.679
D29 Benign neoplasm of male genital organs	0.321	0.679
D28 Benign neoplasm of other and unspecified female genital organs	0.321	0.679
D21 Other benign neoplasms of connective and other soft tissue	0.321	0.679
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.321	0.679
D19 Benign neoplasm of mesothelial tissue	0.321	0.679
D16 Benign neoplasm of bone and articular cartilage	0.321	0.679
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.321	0.679
D14 Benign neoplasm of middle ear and respiratory system	0.321	0.679
M10 Gout	0.320	0.680
D33 Benign neoplasm of brain and other parts of central nervous system	0.320	0.680
S40-S49 Injuries to the shoulder and upper arm	0.319	0.680
D25.2 Subserosal leiomyoma of uterus	0.319	0.681
M81.9 Osteoporosis, unspecified	0.319	0.681
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.319	0.681
T85.2 Mechanical complication of intraocular lens	0.319	0.681
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.319	0.681
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.319	0.681
S82 Fracture of lower leg, including ankle	0.319	0.681
J80-J84 Other respiratory diseases principally affecting the interstitium	0.319	0.681
M24 Other specific joint derangements	0.319	0.681
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.318	0.682
D70-D77 Other diseases of blood and blood-forming organs	0.318	0.682
C16.8 Overlapping lesion of stomach	0.317	0.683
C16.6 Greater curvature of stomach, unspecified	0.317	0.683
C16.5 Lesser curvature of stomach, unspecified	0.317	0.683
C16.4 Pylorus	0.317	0.683
C16.3 Pyloric antrum	0.317	0.683
C16.2 Body of stomach	0.317	0.683
C16.1 Fundus of stomach	0.317	0.683
M25 Other joint disorders, not elsewhere classified	0.316	0.684
W00-W19 Falls	0.316	0.684
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.316	0.684
S88 Traumatic amputation of lower leg	0.316	0.684
S87 Crushing injury of lower leg	0.316	0.684
S86 Injury of muscle and tendon at lower leg level	0.316	0.684
S85 Injury of blood vessels at lower leg level	0.316	0.684
S84 Injury of nerves at lower leg level	0.316	0.684
Chapter VIII Diseases of the ear and mastoid process	0.316	0.684
M14 Arthropathies in other diseases classified elsewhere	0.315	0.685
M12 Other specific arthropathies	0.315	0.685
M09 Juvenile arthritis in diseases classified elsewhere	0.315	0.685
M08 Juvenile arthritis	0.315	0.685
M05 Seropositive rheumatoid arthritis	0.315	0.685
C77.9 Lymph node, unspecified	0.315	0.685
M23 Internal derangement of knee	0.314	0.686
M65 Synovitis and tenosynovitis	0.314	0.686
S22 Fracture of rib(s), sternum and thoracic spine	0.314	0.686
T90 Sequelae of injuries of head	0.314	0.686
D23.6 Skin of upper limb, including shoulder	0.313	0.687
M07 Psoriatic and enteropathic arthropathies	0.313	0.687
T93 Sequelae of injuries of lower limb	0.313	0.687
M45-M49 Spondylopathies	0.313	0.687
J40 Bronchitis, not specified as acute or chronic	0.312	0.687
C25 Malignant neoplasm of pancreas	0.312	0.688
M75.5 Bursitis of shoulder	0.311	0.689
F30-F39 Mood [affective] disorders	0.310	0.690
C15.8 Overlapping lesion of oesophagus	0.309	0.690
C15.4 Middle third of oesophagus	0.309	0.690
C15.3 Upper third of oesophagus	0.309	0.690
C15.2 Abdominal part of oesophagus	0.309	0.690
C15.1 Thoracic part of oesophagus	0.309	0.690
C15.0 Cervical part of oesophagus	0.309	0.690
S59 Other and unspecified injuries of forearm	0.309	0.691
S58 Traumatic amputation of forearm	0.309	0.691
S57 Crushing injury of forearm	0.309	0.691
S56 Injury of muscle and tendon at forearm level	0.309	0.691
S55 Injury of blood vessels at forearm level	0.309	0.691
S54 Injury of nerves at forearm level	0.309	0.691
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.309	0.691
S50 Superficial injury of forearm	0.309	0.691
D80-D89 Certain disorders involving the immune mechanism	0.309	0.691
M75.0 Adhesive capsulitis of shoulder	0.308	0.692
L60.8 Other nail disorders	0.308	0.692
S51.0 Open wound of elbow	0.308	0.692
S91 Open wound of ankle and foot	0.308	0.692
D09 Carcinoma in situ of other and unspecified sites	0.308	0.692
D04 Carcinoma in situ of skin	0.308	0.692
D02 Carcinoma in situ of middle ear and respiratory system	0.308	0.692
D01 Carcinoma in situ of other and unspecified digestive organs	0.308	0.692
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.308	0.692
M34 Systemic sclerosis	0.308	0.692
D51 Vitamin B12 deficiency anaemia	0.307	0.693
Chapter VI Diseases of the nervous system	0.307	0.693
C69 Malignant neoplasm of eye and adnexa	0.306	0.694
D50.9 Iron deficiency anaemia, unspecified	0.304	0.696
D23.1 Skin of eyelid, including canthus	0.304	0.696
S80.9 Superficial injury of lower leg, unspecified	0.304	0.696
F00-F09 Organic, including symptomatic, mental disorders	0.304	0.696
M76 Enthesopathies of lower limb, excluding foot	0.303	0.696
M73 Soft tissue disorders in diseases classified elsewhere	0.303	0.696
M71 Other bursopathies	0.303	0.696
L28 Lichen simplex chronicus and prurigo	0.303	0.696
L25 Unspecified contact dermatitis	0.303	0.696
L24 Irritant contact dermatitis	0.303	0.696
L23 Allergic contact dermatitis	0.303	0.696
L21 Seborrhoeic dermatitis	0.303	0.696
L20 Atopic dermatitis	0.303	0.696
L26 Exfoliative dermatitis	0.303	0.696
L22 Diaper [napkin] dermatitis	0.303	0.696
M53 Other dorsopathies, not elsewhere classified	0.303	0.697
D55-D59 Haemolytic anaemias	0.302	0.698
C02 Malignant neoplasm of other and unspecified parts of tongue	0.302	0.698
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.302	0.698
Q38-Q45 Other congenital malformations of the digestive system	0.302	0.698
D07 Carcinoma in situ of other and unspecified genital organs	0.301	0.698
M11.2 Other chondrocalcinosis	0.301	0.698
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.301	0.699
M50.3 Other cervical disk degeneration	0.301	0.699
W20-W49 Exposure to inanimate mechanical forces	0.300	0.700
S79 Other and unspecified injuries of hip and thigh	0.300	0.700
D23.9 Skin, unspecified	0.300	0.700
D03 Melanoma in situ	0.300	0.700
V20-V29 Motorcycle rider injured in transport accident	0.299	0.701
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.299	0.701
D18 Haemangioma and lymphangioma, any site	0.299	0.701
J43.8 Other emphysema	0.298	0.701
J43.2 Centrilobular emphysema	0.298	0.701
J43.1 Panlobular emphysema	0.298	0.701
J43.0 MacLeod's syndrome	0.298	0.701
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.298	0.702
S17 Crushing injury of neck	0.298	0.702
S15 Injury of blood vessels at neck level	0.298	0.702
S14 Injury of nerves and spinal cord at neck level	0.298	0.702
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.298	0.702
S11 Open wound of neck	0.298	0.702
S10 Superficial injury of neck	0.298	0.702
S18 Traumatic amputation at neck level	0.298	0.702
S16 Injury of muscle and tendon at neck level	0.298	0.702
M13 Other arthritis	0.298	0.702
S83.2 Tear of meniscus, current	0.297	0.703
D23.4 Skin of scalp and neck	0.296	0.704
C79.7 Secondary malignant neoplasm of adrenal gland	0.296	0.704
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.296	0.704
S37 Injury of urinary and pelvic organs	0.296	0.704
S36 Injury of intra-abdominal organs	0.296	0.704
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.296	0.704
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.296	0.704
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.296	0.704
S31 Open wound of abdomen, lower back and pelvis	0.296	0.704
S30 Superficial injury of abdomen, lower back and pelvis	0.296	0.704
D06 Carcinoma in situ of cervix uteri	0.296	0.704
L60.0 Ingrowing nail	0.295	0.705
S27 Injury of other and unspecified intrathoracic organs	0.295	0.705
U80 Agent resistant to penicillin and related antibiotics	0.294	0.705
S99 Other and unspecified injuries of ankle and foot	0.294	0.706
S98 Traumatic amputation of ankle and foot	0.294	0.706
S97 Crushing injury of ankle and foot	0.294	0.706
S96 Injury of muscle and tendon at ankle and foot level	0.294	0.706
S95 Injury of blood vessels at ankle and foot level	0.294	0.706
S94 Injury of nerves at ankle and foot level	0.294	0.706
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.294	0.706
S90 Superficial injury of ankle and foot	0.294	0.706
M15-M19 Arthrosis	0.294	0.706
C79.2 Secondary malignant neoplasm of skin	0.293	0.706
D36.1 Peripheral nerves and autonomic nervous system	0.293	0.707
D13.9 Ill-defined sites within the digestive system	0.293	0.707
D13.7 Endocrine pancreas	0.293	0.707
D13.6 Pancreas	0.293	0.707
D13.5 Extrahepatic bile ducts	0.293	0.707
D13.4 Liver	0.293	0.707
D13.3 Other and unspecified parts of small intestine	0.293	0.707
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.293	0.707
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.292	0.707
L27 Dermatitis due to substances taken internally	0.292	0.708
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.292	0.708
M54.4 Lumbago with sciatica	0.292	0.708
C73 Malignant neoplasm of thyroid gland	0.292	0.708
Q00-Q07 Congenital malformations of the nervous system	0.292	0.708
M31 Other necrotising vasculopathies	0.291	0.709
F80-F89 Disorders of psychological development	0.291	0.709
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.290	0.710
M43 Other deforming dorsopathies	0.289	0.710
M21 Other acquired deformities of limbs	0.289	0.711
L53 Other erythematous conditions	0.289	0.711
T98 Sequelae of other and unspecified effects of external causes	0.289	0.711
T95 Sequelae of burns, corrosions and frostbite	0.289	0.711
T94 Sequelae of injuries involving multiple and unspecified body regions	0.289	0.711
T92 Sequelae of injuries of upper limb	0.289	0.711
T91 Sequelae of injuries of neck and trunk	0.289	0.711
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.289	0.711
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.289	0.711
T88.7 Unspecified adverse effect of drug or medicament	0.288	0.712
M25.7 Osteophyte	0.288	0.712
D45 Polycythaemia vera	0.286	0.714
L50 Urticaria	0.286	0.714
U51 Admission status on psychiatric patients	0.285	0.714
Q60-Q64 Congenital malformations of the urinary system	0.285	0.714
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.285	0.715
Y35-Y36 Legal intervention and operations of war	0.285	0.715
Y10-Y34 Event of undetermined intent	0.285	0.715
Y00-Y09 Assault	0.285	0.715
X85-X99 Assault	0.285	0.715
X60-X84 Intentional self-harm	0.285	0.715
X58-X59 Accidental exposure to other and unspecified factors	0.285	0.715
X50-X57 Overexertion, travel and privation	0.285	0.715
X40-X49 Accidental poisoning by and exposure to noxious substances	0.285	0.715
X30-X39 Exposure to forces of nature	0.285	0.715
X20-X29 Contact with venomous animals and plants	0.285	0.715
X10-X19 Contact with heat and hot substances	0.285	0.715
X00-X09 Exposure to smoke, fire and flames	0.285	0.715
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.285	0.715
W75-W84 Other accidental threats to breathing	0.285	0.715
W65-W74 Accidental drowning and submersion	0.285	0.715
W50-W64 Exposure to animate mechanical forces	0.285	0.715
V98-V99 Other and unspecified transport accidents	0.285	0.715
V95-V97 Air and space transport accidents	0.285	0.715
V90-V94 Water transport accidents	0.285	0.715
V80-V89 Other land transport accidents	0.285	0.715
V70-V79 Bus occupant injured in transport accident	0.285	0.715
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.285	0.715
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.285	0.715
V40-V49 Car occupant injured in transport accident	0.285	0.715
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.285	0.715
V01-V09 Pedestrian injured in transport accident	0.285	0.715
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.285	0.715
M67 Other disorders of synovium and tendon	0.285	0.715
S29 Other and unspecified injuries of thorax	0.284	0.715
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.284	0.715
S26 Injury of heart	0.284	0.715
S25 Injury of blood vessels of thorax	0.284	0.715
S24 Injury of nerves and spinal cord at thorax level	0.284	0.715
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.284	0.715
S21 Open wound of thorax	0.284	0.715
S20 Superficial injury of thorax	0.284	0.715
T36-T50 Poisoning by drugs, medicaments and biological substances	0.284	0.716
D11 Benign neoplasm of major salivary glands	0.284	0.716
M54.57 Low back pain (Lumbosacral region)	0.283	0.716
T83.0 Mechanical complication of urinary (indwelling) catheter	0.283	0.717
J32 Chronic sinusitis	0.283	0.717
C71 Malignant neoplasm of brain	0.282	0.717
Y60-Y69 Misadventures to patients during surgical and medical care	0.282	0.718
L60.9 Nail disorder, unspecified	0.282	0.718
L60.5 Yellow nail syndrome	0.282	0.718
L60.4 Beau's lines	0.282	0.718
L60.3 Nail dystrophy	0.282	0.718
L60.2 Onychogryphosis	0.282	0.718
L60.1 Onycholysis	0.282	0.718
T31 Burns classified according to extent of body surface involved	0.282	0.718
D46 Myelodysplastic syndromes	0.282	0.718
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.281	0.719
M66 Spontaneous rupture of synovium and tendon	0.281	0.719
J36 Peritonsillar abscess	0.281	0.719
M54.56 Low back pain (Lumbar region)	0.281	0.719
M22 Disorders of patella	0.281	0.719
T81 Complications of procedures, not elsewhere classified	0.281	0.719
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.280	0.719
M54.59 Low back pain (Site unspecified)	0.280	0.719
L30.8 Other specified dermatitis	0.280	0.720
J13 Pneumonia due to Streptococcus pneumoniae	0.280	0.720
C78.0 Secondary malignant neoplasm of lung	0.280	0.720
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.279	0.721
C70 Malignant neoplasm of meninges	0.279	0.721
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.278	0.721
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.278	0.721
M33 Dermatopolymyositis	0.278	0.721
M32 Systemic lupus erythematosus	0.278	0.721
M30 Polyarteritis nodosa and related conditions	0.278	0.721
S19.9 Unspecified injury of neck	0.278	0.722
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.278	0.722
D05.7 Other carcinoma in situ of breast	0.278	0.722
D05.0 Lobular carcinoma in situ	0.278	0.722
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.277	0.722
Q80-Q89 Other congenital malformations	0.277	0.722
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.277	0.722
Q50-Q56 Congenital malformations of genital organs	0.277	0.722
Q35-Q37 Cleft lip and cleft palate	0.277	0.722
Q30-Q34 Congenital malformations of the respiratory system	0.277	0.722
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.277	0.722
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.276	0.723
C13 Malignant neoplasm of hypopharynx	0.276	0.723
C11 Malignant neoplasm of nasopharynx	0.276	0.723
C10 Malignant neoplasm of oropharynx	0.276	0.723
C09 Malignant neoplasm of tonsil	0.276	0.723
C08 Malignant neoplasm of other and unspecified major salivary glands	0.276	0.723
C06 Malignant neoplasm of other and unspecified parts of mouth	0.276	0.723
C05 Malignant neoplasm of palate	0.276	0.723
C04 Malignant neoplasm of floor of mouth	0.276	0.723
C03 Malignant neoplasm of gum	0.276	0.723
C00 Malignant neoplasm of lip	0.276	0.723
C12 Malignant neoplasm of pyriform sinus	0.276	0.723
C07 Malignant neoplasm of parotid gland	0.276	0.723
C01 Malignant neoplasm of base of tongue	0.276	0.723
C50-C50 Malignant neoplasm of breast	0.276	0.724
J35 Chronic diseases of tonsils and adenoids	0.276	0.724
J20-J22 Other acute lower respiratory infections	0.276	0.724
M75.8 Other shoulder lesions	0.276	0.724
M75.9 Shoulder lesion, unspecified	0.276	0.724
M75.2 Bicipital tendinitis	0.276	0.724
L30.9 Dermatitis, unspecified	0.275	0.725
S52.0 Fracture of upper end of ulna	0.275	0.725
D32.0 Cerebral meninges	0.275	0.725
F99-F99 Unspecified mental disorder	0.274	0.726
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.274	0.726
F70-F79 Mental retardation	0.274	0.726
F60-F69 Disorders of adult personality and behaviour	0.274	0.726
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.274	0.726
L54 Erythema in diseases classified elsewhere	0.274	0.726
L51 Erythema multiforme	0.274	0.726
L52 Erythema nodosum	0.274	0.726
L00-L08 Infections of the skin and subcutaneous tissue	0.274	0.726
S52.5 Fracture of lower end of radius	0.274	0.726
M81.99 Osteoporosis, unspecified (Site unspecified)	0.274	0.726
M54.16 Radiculopathy (Lumbar region)	0.274	0.726
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.273	0.727
L29.0 Pruritus ani	0.273	0.727
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.273	0.727

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations