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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16991615
log Bayes Factor = 13.5331
Chromosome 20   position 5,948,227  (GRCh37) Explore rs16991615 on Ensembl!
Variant rs16991615 is listed in the   GWAS Catalog   ⇪
Variant rs16991615 is part of Cluster X0306

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N92 Excessive, frequent and irregular menstruation
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
N92.0 Excessive and frequent menstruation with regular cycle
1.000 0.000 0.000
N84 Polyp of female genital tract
1.000 0.000 0.000
N84.0 Polyp of corpus uteri
0.999 0.001 0.000
N95.0 Postmenopausal bleeding
0.999 0.001 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.999 0.001 0.000
N95 Menopausal and other perimenopausal disorders
0.998 0.002 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.996 0.004 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.991 0.009 0.000
N80 Endometriosis
0.991 0.009 0.000
N92.6 Irregular menstruation, unspecified
0.985 0.015 0.000
N80.0 Endometriosis of uterus
0.979 0.021 0.000
D25.9 Leiomyoma of uterus, unspecified
0.978 0.022 0.000
D25 Leiomyoma of uterus
0.975 0.025 0.000
N83.2 Other and unspecified ovarian cysts
0.968 0.032 0.000
C15-C26 Malignant neoplasms of digestive organs
0.962 0.038 0.000
N83.1 Corpus luteum cyst
0.957 0.043 0.000
N85.2 Hypertrophy of uterus
0.956 0.044 0.000
N84.1 Polyp of cervix uteri
0.947 0.053 0.000
C20 Malignant neoplasm of rectum
0.946 0.054 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.943 0.057 0.000
D10-D36 Benign neoplasms
0.933 0.067 0.000
D25.2 Subserosal leiomyoma of uterus
0.932 0.068 0.000
N85.0 Endometrial glandular hyperplasia
0.926 0.074 0.000
C18 Malignant neoplasm of colon
0.925 0.075 0.000
N86 Erosion and ectropion of cervix uteri
0.920 0.080 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.911 0.089 0.000
N83.0 Follicular cyst of ovary
0.907 0.093 0.000
N80.1 Endometriosis of ovary
0.902 0.098 0.000
D25.1 Intramural leiomyoma of uterus
0.899 0.101 0.000
C18.9 Colon, unspecified
0.885 0.115 0.000
N97 Female infertility
0.876 0.124 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.873 0.127 0.000
D12.3 Transverse colon
0.867 0.133 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.856 0.144 0.000
C22.1 Intrahepatic bile duct carcinoma
0.844 0.156 0.000
N88 Other noninflammatory disorders of cervix uteri
0.844 0.156 0.000
N82 Fistulae involving female genital tract
0.840 0.160 0.000
D24 Benign neoplasm of breast
0.831 0.169 0.000
Chapter II Neoplasms
0.827 0.173 0.000
C16 Malignant neoplasm of stomach
0.824 0.176 0.000
D12.4 Descending colon
0.823 0.177 0.000
D23 Other benign neoplasms of skin
0.821 0.179 0.000
C18.2 Ascending colon
0.811 0.189 0.000
C23 Malignant neoplasm of gallbladder
0.799 0.201 0.000
D16 Benign neoplasm of bone and articular cartilage
0.794 0.206 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.786 0.214 0.000
N80.5 Endometriosis of intestine
0.785 0.215 0.000
N80.3 Endometriosis of pelvic peritoneum
0.782 0.218 0.000
N85.6 Intra-uterine synechiae
0.774 0.225 0.000
C18.3 Hepatic flexure
0.762 0.238 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.755 0.245 0.000
D34 Benign neoplasm of thyroid gland
0.747 0.253 0.000
D27 Benign neoplasm of ovary
0.742 0.258 0.000
N97.1 Female infertility of tubal origin
0.740 0.260 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.736 0.264 0.000
C22.9 Liver, unspecified
0.734 0.266 0.000
D00-D09 In situ neoplasms
0.721 0.279 0.000
D23.0 Skin of lip
0.720 0.280 0.000
N92.2 Excessive menstruation at puberty
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
N84.9 Polyp of female genital tract, unspecified
0.717 0.283 0.000
N84.8 Polyp of other parts of female genital tract
0.717 0.283 0.000
C25 Malignant neoplasm of pancreas
0.716 0.284 0.000
N97.9 Female infertility, unspecified
0.716 0.284 0.000
N85.1 Endometrial adenomatous hyperplasia
0.716 0.284 0.000
C16.0 Cardia
0.715 0.285 0.000
N83.7 Haematoma of broad ligament
0.714 0.286 0.000
N83.6 Haematosalpinx
0.714 0.286 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.714 0.286 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.714 0.286 0.000
D30 Benign neoplasm of urinary organs
0.712 0.288 0.000
D23.3 Skin of other and unspecified parts of face
0.712 0.288 0.000
D31 Benign neoplasm of eye and adnexa
0.711 0.289 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.711 0.289 0.000
N85.7 Haematometra
0.710 0.290 0.000
N85.5 Inversion of uterus
0.710 0.290 0.000
N85.3 Subinvolution of uterus
0.710 0.290 0.000
N80.6 Endometriosis in cutaneous scar
0.710 0.290 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.710 0.290 0.000
N88.2 Stricture and stenosis of cervix uteri
0.710 0.290 0.000
C22.0 Liver cell carcinoma
0.707 0.293 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.705 0.295 0.000
N91 Absent, scanty and rare menstruation
0.705 0.295 0.000
C18.4 Transverse colon
0.700 0.300 0.000
N80.2 Endometriosis of Fallopian tube
0.698 0.302 0.000
D29 Benign neoplasm of male genital organs
0.698 0.302 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.691 0.309 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.690 0.310 0.000
N82.4 Other female intestinal-genital tract fistulae
0.686 0.314 0.000
C17 Malignant neoplasm of small intestine
0.684 0.316 0.000
D23.1 Skin of eyelid, including canthus
0.681 0.319 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.678 0.322 0.000
N84.3 Polyp of vulva
0.678 0.322 0.000
C21 Malignant neoplasm of anus and anal canal
0.678 0.322 0.000
D16.5 Lower jaw bone
0.678 0.322 0.000
N88.1 Old laceration of cervix uteri
0.677 0.322 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.676 0.324 0.000
N92.4 Excessive bleeding in the premenopausal period
0.675 0.325 0.000
N92.5 Other specified irregular menstruation
0.675 0.325 0.000
N85.4 Malposition of uterus
0.673 0.327 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.669 0.331 0.000
D19 Benign neoplasm of mesothelial tissue
0.669 0.331 0.000
D32 Benign neoplasm of meninges
0.666 0.334 0.000
N82.3 Fistula of vagina to large intestine
0.664 0.336 0.000
N84.2 Polyp of vagina
0.664 0.336 0.000
C18.8 Overlapping lesion of colon
0.663 0.337 0.000
C18.1 Appendix
0.660 0.340 0.000
C26.0 Intestinal tract, part unspecified
0.660 0.340 0.000
D12.9 Anus and anal canal
0.659 0.341 0.000
C22.7 Other specified carcinomas of liver
0.653 0.347 0.000
C22.4 Other sarcomas of liver
0.653 0.347 0.000
C22.3 Angiosarcoma of liver
0.653 0.347 0.000
C22.2 Hepatoblastoma
0.653 0.347 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.652 0.348 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.650 0.350 0.000
D23.9 Skin, unspecified
0.649 0.351 0.000
D12.2 Ascending colon
0.646 0.354 0.000
D28.1 Vagina
0.643 0.357 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.629 0.371 0.000
N97.8 Female infertility of other origin
0.628 0.371 0.000
N97.4 Female infertility associated with male factors
0.628 0.371 0.000
N97.3 Female infertility of cervical origin
0.628 0.371 0.000
N97.2 Female infertility of uterine origin
0.628 0.371 0.000
N97.0 Female infertility associated with anovulation
0.628 0.371 0.000
N80.8 Other endometriosis
0.627 0.372 0.000
D12.1 Appendix
0.626 0.374 0.000
D16.2 Long bones of lower limb
0.623 0.377 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.622 0.378 0.000
D25.0 Submucous leiomyoma of uterus
0.621 0.379 0.000
D17 Benign lipomatous neoplasm
0.620 0.380 0.000
C18.6 Descending colon
0.618 0.382 0.000
D23.7 Skin of lower limb, including hip
0.615 0.385 0.000
D16.1 Short bones of upper limb
0.615 0.385 0.000
C16.9 Stomach, unspecified
0.612 0.388 0.000
C18.5 Splenic flexure
0.610 0.389 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.607 0.392 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.605 0.395 0.000
N88.3 Incompetence of cervix uteri
0.605 0.395 0.000
N88.0 Leukoplakia of cervix uteri
0.605 0.395 0.000
N82.9 Female genital tract fistula, unspecified
0.603 0.397 0.000
N82.8 Other female genital tract fistulae
0.603 0.397 0.000
N82.5 Female genital tract-skin fistulae
0.603 0.397 0.000
N82.2 Fistula of vagina to small intestine
0.603 0.397 0.000
N82.1 Other female urinary-genital tract fistulae
0.603 0.397 0.000
N82.0 Vesicovaginal fistula
0.603 0.397 0.000
C18.7 Sigmoid colon
0.602 0.398 0.000
D11 Benign neoplasm of major salivary glands
0.598 0.402 0.000
D30.0 Kidney
0.596 0.404 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.593 0.407 0.000
C16.8 Overlapping lesion of stomach
0.591 0.409 0.000
C16.6 Greater curvature of stomach, unspecified
0.591 0.409 0.000
C16.5 Lesser curvature of stomach, unspecified
0.591 0.409 0.000
C16.4 Pylorus
0.591 0.409 0.000
C16.3 Pyloric antrum
0.591 0.409 0.000
C16.2 Body of stomach
0.591 0.409 0.000
C16.1 Fundus of stomach
0.591 0.409 0.000
D13.2 Duodenum
0.590 0.410 0.000
N95.3 States associated with artificial menopause
0.590 0.410 0.000
D23.6 Skin of upper limb, including shoulder
0.585 0.415 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.582 0.418 0.000
D05 Carcinoma in situ of breast
0.581 0.419 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.580 0.420 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.573 0.427 0.000
D13.3 Other and unspecified parts of small intestine
0.571 0.429 0.000
D16.9 Bone and articular cartilage, unspecified
0.569 0.431 0.000
D16.8 Pelvic bones, sacrum and coccyx
0.569 0.431 0.000
D16.7 Ribs, sternum and clavicle
0.569 0.431 0.000
D16.6 Vertebral column
0.569 0.431 0.000
D16.0 Scapula and long bones of upper limb
0.569 0.431 0.000
D23.2 Skin of ear and external auricular canal
0.568 0.432 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.566 0.434 0.000
D26 Other benign neoplasms of uterus
0.566 0.434 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.564 0.436 0.000
C26.9 Ill-defined sites within the digestive system
0.564 0.436 0.000
C26.8 Overlapping lesion of digestive system
0.564 0.436 0.000
C26.1 Spleen
0.564 0.436 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.562 0.438 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.558 0.442 0.000
D16.3 Short bones of lower limb
0.558 0.442 0.000
D04 Carcinoma in situ of skin
0.554 0.446 0.000
D12.8 Rectum
0.552 0.448 0.000
D28.2 Uterine tubes and ligaments
0.549 0.451 0.000
C25.9 Pancreas, unspecified
0.549 0.451 0.000
D13.5 Extrahepatic bile ducts
0.546 0.454 0.000
D28.9 Female genital organ, unspecified
0.541 0.459 0.000
D28.7 Other specified female genital organs
0.541 0.459 0.000
D32.1 Spinal meninges
0.539 0.461 0.000
D03 Melanoma in situ
0.538 0.462 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.535 0.465 0.000
D31.0 Conjunctiva
0.534 0.466 0.000
D05.1 Intraductal carcinoma in situ
0.533 0.467 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.532 0.468 0.000
D31.3 Choroid
0.529 0.471 0.000
D29.1 Prostate
0.528 0.471 0.000
D36 Benign neoplasm of other and unspecified sites
0.528 0.472 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.527 0.473 0.000
D00.0 Lip, oral cavity and pharynx
0.526 0.474 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.517 0.483 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.516 0.484 0.000
D15.1 Heart
0.515 0.484 0.000
D09 Carcinoma in situ of other and unspecified sites
0.515 0.485 0.000
N98.9 Complication associated with artificial fertilisation, unspecified
0.514 0.486 0.000
N98.8 Other complications associated with artificial fertilisation
0.514 0.486 0.000
N98.3 Complications of attempted introduction of embryo in embryo transfer
0.514 0.486 0.000
N98.2 Complications of attempted introduction of fertilised ovum following in vitro fertilisation
0.514 0.486 0.000
N98.1 Hyperstimulation of ovaries
0.514 0.486 0.000
N98.0 Infection associated with artificial insemination
0.514 0.486 0.000
C25.8 Overlapping lesion of pancreas
0.513 0.486 0.000
C25.7 Other parts of pancreas
0.513 0.486 0.000
C25.4 Endocrine pancreas
0.513 0.486 0.000
C25.3 Pancreatic duct
0.513 0.486 0.000
C25.2 Tail of pancreas
0.513 0.486 0.000
C25.1 Body of pancreas
0.513 0.486 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.512 0.488 0.000
D13.9 Ill-defined sites within the digestive system
0.512 0.488 0.000
D13.7 Endocrine pancreas
0.512 0.488 0.000
D13.6 Pancreas
0.512 0.488 0.000
D13.4 Liver
0.512 0.488 0.000
D30.9 Urinary organ, unspecified
0.511 0.489 0.000
D30.7 Other urinary organs
0.511 0.489 0.000
D30.4 Urethra
0.511 0.489 0.000
D30.2 Ureter
0.511 0.489 0.000
D30.1 Renal pelvis
0.511 0.489 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.510 0.490 0.000
D31.9 Eye, unspecified
0.509 0.490 0.000
D31.6 Orbit, unspecified
0.509 0.490 0.000
D31.5 Lachrymal gland and duct
0.509 0.490 0.000
D31.4 Ciliary body
0.509 0.490 0.000
D31.2 Retina
0.509 0.490 0.000
D31.1 Cornea
0.509 0.490 0.000
N91.5 Oligomenorrhoea, unspecified
0.505 0.495 0.000
N91.4 Secondary oligomenorrhoea
0.505 0.495 0.000
N91.3 Primary oligomenorrhoea
0.505 0.495 0.000
N91.1 Secondary amenorrhoea
0.505 0.495 0.000
N91.0 Primary amenorrhoea
0.505 0.495 0.000
C15 Malignant neoplasm of oesophagus
0.505 0.495 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.504 0.496 0.000
C17.2 Ileum
0.503 0.496 0.000
C25.0 Head of pancreas
0.502 0.498 0.000
D28.0 Vulva
0.501 0.499 0.000
C18.0 Caecum
0.500 0.499 0.000
D29.9 Male genital organ, unspecified
0.500 0.500 0.000
D29.7 Other male genital organs
0.500 0.500 0.000
D29.4 Scrotum
0.500 0.500 0.000
D29.3 Epididymis
0.500 0.500 0.000
D29.2 Testis
0.500 0.500 0.000
D29.0 Penis
0.500 0.500 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.500 0.500 0.000
C24.0 Extrahepatic bile duct
0.495 0.505 0.000
D15.9 Intrathoracic organ, unspecified
0.495 0.505 0.000
D15.7 Other specified intrathoracic organs
0.495 0.505 0.000
D15.2 Mediastinum
0.495 0.505 0.000
D15.0 Thymus
0.495 0.505 0.000
D04.3 Skin of other and unspecified parts of face
0.495 0.505 0.000
D06 Carcinoma in situ of cervix uteri
0.494 0.506 0.000
N91.2 Amenorrhoea, unspecified
0.493 0.507 0.000
C17.0 Duodenum
0.492 0.508 0.000
C50-C50 Malignant neoplasm of breast
0.492 0.508 0.000
C17.8 Overlapping lesion of small intestine
0.490 0.510 0.000
C17.3 Meckel's diverticulum
0.490 0.510 0.000
C17.1 Jejunum
0.490 0.510 0.000
C21.0 Anus, unspecified
0.489 0.511 0.000
D16.4 Bones of skull and face
0.487 0.512 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.486 0.513 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.486 0.514 0.000
C21.2 Cloacogenic zone
0.486 0.514 0.000
C24.9 Biliary tract, unspecified
0.484 0.515 0.000
C24.8 Overlapping lesion of biliary tract
0.484 0.515 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.485 0.515 0.000
D19.9 Mesothelial tissue, unspecified
0.480 0.520 0.000
D19.7 Mesothelial tissue of other sites
0.480 0.520 0.000
D19.1 Mesothelial tissue of peritoneum
0.480 0.520 0.000
D19.0 Mesothelial tissue of pleura
0.480 0.520 0.000
D20.1 Peritoneum
0.480 0.520 0.000
D20.0 Retroperitoneum
0.480 0.520 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.478 0.522 0.000
D13.0 Oesophagus
0.478 0.522 0.000
D37.2 Small intestine
0.478 0.522 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.476 0.524 0.000
D45 Polycythaemia vera
0.475 0.525 0.000
N95.1 Menopausal and female climacteric states
0.474 0.526 0.001
D21.2 Connective and other soft tissue of lower limb, including hip
0.474 0.526 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.473 0.527 0.000
D32.9 Meninges, unspecified
0.473 0.527 0.000
C21.1 Anal canal
0.470 0.530 0.000
D44.1 Adrenal gland
0.468 0.532 0.000
D48.5 Skin
0.468 0.532 0.000
D21.9 Connective and other soft tissue, unspecified
0.467 0.533 0.000
D21.6 Connective and other soft tissue of trunk, unspecified
0.467 0.533 0.000
D21.5 Connective and other soft tissue of pelvis
0.467 0.533 0.000
D21.4 Connective and other soft tissue of abdomen
0.467 0.533 0.000
D21.3 Connective and other soft tissue of thorax
0.467 0.533 0.000
C17.9 Small intestine, unspecified
0.467 0.533 0.000
D33.9 Central nervous system, unspecified
0.466 0.534 0.000
D33.7 Other specified parts of central nervous system
0.466 0.534 0.000
D33.4 Spinal cord
0.466 0.534 0.000
D33.2 Brain, unspecified
0.466 0.534 0.000
D33.1 Brain, infratentorial
0.466 0.534 0.000
D33.0 Brain, supratentorial
0.466 0.534 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.465 0.535 0.000
D05.7 Other carcinoma in situ of breast
0.463 0.537 0.000
D23.5 Skin of trunk
0.463 0.537 0.000
C24.1 Ampulla of Vater
0.459 0.541 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.453 0.546 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.453 0.547 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.450 0.550 0.000
D37.7 Other digestive organs
0.450 0.550 0.000
D37.5 Rectum
0.449 0.550 0.000
D02.0 Larynx
0.448 0.552 0.000
D33.3 Cranial nerves
0.447 0.553 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.445 0.555 0.000
D35.2 Pituitary gland
0.442 0.558 0.000
N89 Other noninflammatory disorders of vagina
0.439 0.561 0.000
D03.4 Melanoma in situ of scalp and neck
0.437 0.563 0.000
D30.3 Bladder
0.436 0.564 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.436 0.564 0.000
N92.3 Ovulation bleeding
0.436 0.564 0.000
D00.2 Stomach
0.436 0.564 0.000
D00.1 Oesophagus
0.436 0.564 0.000
D10 Benign neoplasm of mouth and pharynx
0.429 0.570 0.001
D37.0 Lip, oral cavity and pharynx
0.430 0.570 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.429 0.571 0.000
D11.9 Major salivary gland, unspecified
0.429 0.571 0.000
D11.7 Other major salivary glands
0.429 0.571 0.000
D40.1 Testis
0.427 0.573 0.000
C60-C63 Malignant neoplasms of male genital organs
0.425 0.575 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.425 0.575 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.425 0.575 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.425 0.575 0.000
D26.9 Uterus, unspecified
0.423 0.577 0.000
D18 Haemangioma and lymphangioma, any site
0.419 0.580 0.000
C37 Malignant neoplasm of thymus
0.418 0.582 0.000
D14.4 Respiratory system, unspecified
0.416 0.584 0.000
D14.3 Bronchus and lung
0.416 0.584 0.000
D14.2 Trachea
0.416 0.584 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.413 0.587 0.000
D48.0 Bone and articular cartilage
0.413 0.587 0.000
D05.0 Lobular carcinoma in situ
0.411 0.589 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.410 0.589 0.001
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.411 0.589 0.000
C46 Kaposi's sarcoma
0.411 0.589 0.000
C81 Hodgkin's disease
0.409 0.591 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.407 0.593 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.407 0.593 0.000
D44.3 Pituitary gland
0.406 0.594 0.000
D26.7 Other parts of uterus
0.406 0.594 0.000
D37.9 Digestive organ, unspecified
0.405 0.595 0.000
D37.6 Liver, gallbladder and bile ducts
0.405 0.595 0.000
D37.3 Appendix
0.405 0.595 0.000
C45 Mesothelioma
0.404 0.596 0.000
D02.4 Respiratory system, unspecified
0.403 0.597 0.000
D02.3 Other parts of respiratory system
0.403 0.597 0.000
D02.2 Bronchus and lung
0.403 0.597 0.000
D02.1 Trachea
0.403 0.597 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.402 0.598 0.000
D44.9 Endocrine gland, unspecified
0.400 0.600 0.000
D44.8 Pluriglandular involvement
0.400 0.600 0.000
D44.7 Aortic body and other paraganglia
0.400 0.600 0.000
D44.6 Carotid body
0.400 0.600 0.000
D44.5 Pineal gland
0.400 0.600 0.000
D44.4 Craniopharyngeal duct
0.400 0.600 0.000
D44.2 Parathyroid gland
0.400 0.600 0.000
D44.0 Thyroid gland
0.400 0.600 0.000
D46 Myelodysplastic syndromes
0.398 0.602 0.000
D48.7 Other specified sites
0.398 0.602 0.000
D04.9 Skin, unspecified
0.397 0.603 0.000
D04.8 Skin of other sites
0.397 0.603 0.000
D04.4 Skin of scalp and neck
0.397 0.603 0.000
D04.2 Skin of ear and external auricular canal
0.397 0.603 0.000
D04.1 Skin of eyelid, including canthus
0.397 0.603 0.000
D04.0 Skin of lip
0.397 0.603 0.000
D36.7 Other specified sites
0.397 0.603 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.397 0.603 0.000
D14.1 Larynx
0.396 0.604 0.000
D12.7 Rectosigmoid junction
0.394 0.606 0.000
D12.0 Caecum
0.393 0.607 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.393 0.607 0.000
D04.7 Skin of lower limb, including hip
0.392 0.608 0.000
C15.3 Upper third of oesophagus
0.391 0.609 0.000
C05 Malignant neoplasm of palate
0.387 0.613 0.000
D03.9 Melanoma in situ, unspecified
0.386 0.614 0.000
D03.8 Melanoma in situ of other sites
0.386 0.614 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.386 0.614 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.386 0.614 0.000
D03.0 Melanoma in situ of lip
0.386 0.614 0.000
D32.0 Cerebral meninges
0.386 0.614 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.384 0.616 0.001
D35.9 Endocrine gland, unspecified
0.384 0.616 0.000
D35.8 Pluriglandular involvement
0.384 0.616 0.000
D35.7 Other specified endocrine glands
0.384 0.616 0.000
D35.6 Aortic body and other paraganglia
0.384 0.616 0.000
D35.5 Carotid body
0.384 0.616 0.000
D35.4 Pineal gland
0.384 0.616 0.000
D35.3 Craniopharyngeal duct
0.384 0.616 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.384 0.616 0.000
D40.9 Male genital organ, unspecified
0.381 0.618 0.000
D40.7 Other male genital organs
0.381 0.618 0.000
D40.0 Prostate
0.381 0.618 0.000
D37.1 Stomach
0.380 0.620 0.000
D36.9 Benign neoplasm of unspecified site
0.379 0.621 0.000
D36.0 Lymph nodes
0.379 0.621 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.378 0.621 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.378 0.622 0.000
D48.4 Peritoneum
0.378 0.622 0.000
D48.3 Retroperitoneum
0.378 0.622 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.378 0.622 0.000
C15.4 Middle third of oesophagus
0.375 0.624 0.000
D26.1 Corpus uteri
0.373 0.627 0.000
C10 Malignant neoplasm of oropharynx
0.372 0.628 0.000
D01.9 Digestive organ, unspecified
0.371 0.629 0.000
D01.7 Other specified digestive organs
0.371 0.629 0.000
D01.5 Liver, gallbladder and bile ducts
0.371 0.629 0.000
D01.4 Other and unspecified parts of intestine
0.371 0.629 0.000
D01.3 Anus and anal canal
0.371 0.629 0.000
D01.2 Rectum
0.371 0.629 0.000
D01.1 Rectosigmoid junction
0.371 0.629 0.000
D01.0 Colon
0.371 0.629 0.000
D09.9 Carcinoma in situ, unspecified
0.369 0.630 0.000
D09.7 Carcinoma in situ of other specified sites
0.369 0.630 0.000
D09.3 Thyroid and other endocrine glands
0.369 0.630 0.000
D09.2 Eye
0.369 0.630 0.000
D09.1 Other and unspecified urinary organs
0.369 0.630 0.000
D09.0 Bladder
0.368 0.632 0.000
C51-C58 Malignant neoplasms of female genital organs
0.367 0.633 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.367 0.633 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.366 0.634 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.366 0.634 0.000
C31 Malignant neoplasm of accessory sinuses
0.366 0.634 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.366 0.634 0.000
C33 Malignant neoplasm of trachea
0.366 0.634 0.000
C07 Malignant neoplasm of parotid gland
0.364 0.636 0.000
D47.2 Monoclonal gammopathy
0.363 0.637 0.000
C15.8 Overlapping lesion of oesophagus
0.362 0.637 0.000
C15.2 Abdominal part of oesophagus
0.362 0.637 0.000
C15.1 Thoracic part of oesophagus
0.362 0.637 0.000
C15.0 Cervical part of oesophagus
0.362 0.637 0.000
C13 Malignant neoplasm of hypopharynx
0.362 0.638 0.000
C11 Malignant neoplasm of nasopharynx
0.362 0.638 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.362 0.638 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.362 0.638 0.000
C04 Malignant neoplasm of floor of mouth
0.362 0.638 0.000
C03 Malignant neoplasm of gum
0.362 0.638 0.000
C00 Malignant neoplasm of lip
0.362 0.638 0.000
C12 Malignant neoplasm of pyriform sinus
0.362 0.638 0.000
D04.6 Skin of upper limb, including shoulder
0.358 0.642 0.000
D11.0 Parotid gland
0.357 0.643 0.000
D06.7 Other parts of cervix
0.354 0.646 0.000
D06.1 Exocervix
0.354 0.646 0.000
D06.0 Endocervix
0.354 0.646 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.353 0.647 0.000
C91 Lymphoid leukaemia
0.350 0.650 0.000
D42.9 Meninges, unspecified
0.349 0.651 0.000
D42.1 Spinal meninges
0.349 0.651 0.000
D42.0 Cerebral meninges
0.349 0.651 0.000
D39.9 Female genital organ, unspecified
0.347 0.652 0.000
D39.7 Other female genital organs
0.347 0.652 0.000
D39.2 Placenta
0.347 0.652 0.000
D39.0 Uterus
0.347 0.652 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.346 0.653 0.000
D39.1 Ovary
0.345 0.654 0.000
C48.1 Specified parts of peritoneum
0.344 0.656 0.000
D13.1 Stomach
0.342 0.658 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.341 0.658 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.341 0.658 0.000
D47.4 Osteomyelofibrosis
0.341 0.658 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.341 0.658 0.000
D43.9 Central nervous system, unspecified
0.339 0.661 0.000
D43.7 Other parts of central nervous system
0.339 0.661 0.000
D43.4 Spinal cord
0.339 0.661 0.000
D43.3 Cranial nerves
0.339 0.661 0.000
D43.1 Brain, infratentorial
0.339 0.661 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.337 0.663 0.000
C88 Malignant immunoproliferative diseases
0.336 0.664 0.000
C81.9 Hodgkin's disease, unspecified
0.335 0.665 0.000
D43.0 Brain, supratentorial
0.335 0.665 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.333 0.666 0.000
C95 Leukaemia of unspecified cell type
0.333 0.666 0.000
C94 Other leukaemias of specified cell type
0.333 0.666 0.000
C93 Monocytic leukaemia
0.333 0.666 0.000
C86 Other specified types of T/NK-cell lymphoma
0.333 0.666 0.000
C62 Malignant neoplasm of testis
0.332 0.668 0.000
D06.9 Cervix, unspecified
0.331 0.669 0.000
D43.2 Brain, unspecified
0.331 0.669 0.000
N95.2 Postmenopausal atrophic vaginitis
0.328 0.671 0.000
C81.0 Lymphocytic predominance
0.328 0.672 0.000
D35.0 Adrenal gland
0.326 0.673 0.000
D38.6 Respiratory organ, unspecified
0.325 0.675 0.000
D38.5 Other respiratory organs
0.325 0.675 0.000
D38.4 Thymus
0.325 0.675 0.000
D38.3 Mediastinum
0.325 0.675 0.000
D38.2 Pleura
0.325 0.675 0.000
D38.0 Larynx
0.325 0.675 0.000
C09 Malignant neoplasm of tonsil
0.325 0.675 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.324 0.676 0.000
D41.0 Kidney
0.323 0.677 0.000
D41.9 Urinary organ, unspecified
0.323 0.677 0.000
D41.7 Other urinary organs
0.323 0.677 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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