TreeWAS – Variant ID: rs17020489

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.997	0.003
Chapter XI Diseases of the digestive system	0.994	0.006
Chapter XXI Factors influencing health status and contact with health services	0.987	0.013
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.970	0.030
K55-K64 Other diseases of intestines	0.956	0.044
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.951	0.049
Chapter IX Diseases of the circulatory system	0.946	0.054
K57 Diverticular disease of intestine	0.912	0.088
Chapter XII Diseases of the skin and subcutaneous tissue	0.893	0.107
K40-K46 Hernia	0.885	0.115
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.885	0.115
Z95 Presence of cardiac and vascular implants and grafts	0.884	0.116
K57.3 Diverticular disease of large intestine without perforation or abscess	0.881	0.119
Chapter VI Diseases of the nervous system	0.862	0.138
Z00-Z13 Persons encountering health services for examination and investigation	0.849	0.151
I20-I25 Ischaemic heart diseases	0.845	0.155
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.839	0.161
R50-R69 General symptoms and signs	0.838	0.162
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.838	0.162
Chapter XIV Diseases of the genitourinary system	0.829	0.171
Chapter VII Diseases of the eye and adnexa	0.828	0.172
K20-K31 Diseases of oesophagus, stomach and duodenum	0.826	0.174
K44 Diaphragmatic hernia	0.820	0.180
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.814	0.186
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.807	0.193
K59 Other functional intestinal disorders	0.797	0.203
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.797	0.203
K65-K67 Diseases of peritoneum	0.788	0.212
Z87 Personal history of other diseases and conditions	0.786	0.214
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.779	0.221
I25 Chronic ischaemic heart disease	0.779	0.221
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.773	0.227
Z95.0 Presence of cardiac pacemaker	0.769	0.231
Z92 Personal history of medical treatment	0.762	0.238
Z80 Family history of malignant neoplasm	0.759	0.241
L80-L99 Other disorders of the skin and subcutaneous tissue	0.756	0.244
Chapter II Neoplasms	0.753	0.247
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.752	0.248
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.751	0.249
I30-I52 Other forms of heart disease	0.751	0.249
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.747	0.252
G40-G47 Episodic and paroxysmal disorders	0.747	0.253
N80-N98 Noninflammatory disorders of female genital tract	0.747	0.253
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.743	0.257
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.740	0.260
I10-I15 Hypertensive diseases	0.738	0.262
Z37 Outcome of delivery	0.736	0.264
Chapter XV Pregnancy, childbirth and the puerperium	0.734	0.266
K02 Dental caries	0.731	0.269
K05 Gingivitis and periodontal diseases	0.728	0.272
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.719	0.281
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.718	0.282
K58 Irritable bowel syndrome	0.718	0.282
R69 Unknown and unspecified causes of morbidity	0.717	0.283
L00-L08 Infections of the skin and subcutaneous tissue	0.715	0.285
Chapter XXII Codes for special purposes	0.715	0.285
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
Chapter VIII Diseases of the ear and mastoid process	0.715	0.285
Z86 Personal history of certain other diseases	0.713	0.287
K70-K77 Diseases of liver	0.713	0.287
K35-K38 Diseases of appendix	0.713	0.287
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.707	0.292
I70-I79 Diseases of arteries, arterioles and capillaries	0.707	0.293
Chapter XX External causes of morbidity and mortality	0.705	0.295
Z95.5 Presence of coronary angioplasty implant and graft	0.705	0.295
K90-K93 Other diseases of the digestive system	0.704	0.296
R51 Headache	0.702	0.298
L40-L45 Papulosquamous disorders	0.700	0.299
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.698	0.302
Chapter I Certain infectious and parasitic diseases	0.697	0.303
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.696	0.304
Z98 Other postsurgical states	0.696	0.304
Z97 Presence of other devices	0.696	0.304
Z94 Transplanted organ and tissue status	0.696	0.304
Z93 Artificial opening status	0.696	0.304
Z91 Personal history of risk-factors, not elsewhere classified	0.696	0.304
Z89 Acquired absence of limb	0.696	0.304
Z84 Family history of other conditions	0.696	0.304
Z83 Family history of other specific disorders	0.696	0.304
Z81 Family history of mental and behavioural disorders	0.696	0.304
Z95.1 Presence of aortocoronary bypass graft	0.694	0.306
K63 Other diseases of intestine	0.693	0.307
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.693	0.307
Z96 Presence of other functional implants	0.692	0.308
Z90 Acquired absence of organs, not elsewhere classified	0.688	0.312
K42 Umbilical hernia	0.687	0.313
Z87.1 Personal history of diseases of the digestive system	0.686	0.314
K64 Haemorrhoids and perianal venous thrombosis	0.685	0.315
K61 Abscess of anal and rectal regions	0.685	0.315
K60 Fissure and fistula of anal and rectal regions	0.685	0.315
K56 Paralytic ileus and intestinal obstruction without hernia	0.685	0.315
K55 Vascular disorders of intestine	0.685	0.315
K59.0 Constipation	0.684	0.316
R95-R99 Ill-defined and unknown causes of mortality	0.682	0.318
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.682	0.318
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.682	0.318
R47-R49 Symptoms and signs involving speech and voice	0.682	0.318
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.682	0.318
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.682	0.318
K22 Other diseases of oesophagus	0.682	0.318
K01 Embedded and impacted teeth	0.682	0.318
Z85 Personal history of malignant neoplasm	0.679	0.321
I95-I99 Other and unspecified disorders of the circulatory system	0.678	0.322
I60-I69 Cerebrovascular diseases	0.678	0.322
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.678	0.322
I05-I09 Chronic rheumatic heart diseases	0.678	0.322
I00-I02 Acute rheumatic fever	0.678	0.322
K50-K52 Noninfective enteritis and colitis	0.673	0.327
N17-N19 Renal failure	0.673	0.327
Z03 Medical observation and evaluation for suspected diseases and conditions	0.673	0.327
I25.2 Old myocardial infarction	0.669	0.331
H25-H28 Disorders of lens	0.667	0.333
Chapter IV Endocrine, nutritional and metabolic diseases	0.665	0.335
Chapter V Mental and behavioural disorders	0.661	0.339
Z37.0 Single live birth	0.661	0.339
N92 Excessive, frequent and irregular menstruation	0.661	0.339
R41 Other symptoms and signs involving cognitive functions and awareness	0.658	0.342
G50-G59 Nerve, nerve root and plexus disorders	0.657	0.343
K80 Cholelithiasis	0.655	0.345
I83 Varicose veins of lower extremities	0.654	0.346
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.654	0.346
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.654	0.346
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.654	0.346
K57.2 Diverticular disease of large intestine with perforation and abscess	0.654	0.346
K57.1 Diverticular disease of small intestine without perforation or abscess	0.654	0.346
K57.0 Diverticular disease of small intestine with perforation and abscess	0.654	0.346
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.653	0.347
Z88.1 Personal history of allergy to other antibiotic agents	0.651	0.349
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.651	0.349
I25.8 Other forms of chronic ischaemic heart disease	0.651	0.349
R42 Dizziness and giddiness	0.650	0.350
R00 Abnormalities of heart beat	0.649	0.351
R06 Abnormalities of breathing	0.647	0.353
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.641	0.359
K66 Other disorders of peritoneum	0.640	0.360
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.640	0.360
L50-L54 Urticaria and erythema	0.640	0.360
L20-L30 Dermatitis and eczema	0.640	0.360
L10-L14 Bullous disorders	0.640	0.360
I25.9 Chronic ischaemic heart disease, unspecified	0.638	0.362
R04 Haemorrhage from respiratory passages	0.637	0.363
Z12 Special screening examination for neoplasms	0.637	0.363
L97 Ulcer of lower limb, not elsewhere classified	0.635	0.365
L60-L75 Disorders of skin appendages	0.635	0.365
K46 Unspecified abdominal hernia	0.634	0.365
K45 Other abdominal hernia	0.634	0.365
K41 Femoral hernia	0.634	0.365
K14 Diseases of tongue	0.634	0.365
K13 Other diseases of lip and oral mucosa	0.634	0.365
K12 Stomatitis and related lesions	0.634	0.365
K11 Diseases of salivary glands	0.634	0.365
K10 Other diseases of jaws	0.634	0.365
K09 Cysts of oral region, not elsewhere classified	0.634	0.365
K08 Other disorders of teeth and supporting structures	0.634	0.365
K07 Dentofacial anomalies [including malocclusion]	0.634	0.365
K06 Other disorders of gingiva and edentulous alveolar ridge	0.634	0.365
K04 Diseases of pulp and periapical tissues	0.634	0.365
K03 Other diseases of hard tissues of teeth	0.634	0.365
K00 Disorders of tooth development and eruption	0.634	0.365
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.634	0.366
Z95.8 Presence of other cardiac and vascular implants and grafts	0.634	0.366
Z95.4 Presence of other heart-valve replacement	0.634	0.366
Z95.3 Presence of xenogenic heart valve	0.634	0.366
Z95.2 Presence of prosthetic heart valve	0.634	0.366
K43 Ventral hernia	0.630	0.370
Z92.1 Personal history of long-term (current) use of anticoagulants	0.630	0.370
G47 Sleep disorders	0.628	0.372
Z70-Z76 Persons encountering health services in other circumstances	0.627	0.372
K31 Other diseases of stomach and duodenum	0.623	0.377
Z13 Special screening examination for other diseases and disorders	0.623	0.377
K02.9 Dental caries, unspecified	0.621	0.379
K21 Gastro-oesophageal reflux disease	0.619	0.381
G90-G99 Other disorders of the nervous system	0.618	0.382
G80-G83 Cerebral palsy and other paralytic syndromes	0.618	0.382
G70-G73 Diseases of myoneural junction and muscle	0.618	0.382
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.618	0.382
G35-G37 Demyelinating diseases of the central nervous system	0.618	0.382
G30-G32 Other degenerative diseases of the nervous system	0.618	0.382
G20-G26 Extrapyramidal and movement disorders	0.618	0.382
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.618	0.382
G00-G09 Inflammatory diseases of the central nervous system	0.618	0.382
R53 Malaise and fatigue	0.616	0.384
K05.3 Chronic periodontitis	0.615	0.385
R55 Syncope and collapse	0.614	0.386
D10-D36 Benign neoplasms	0.614	0.386
K25 Gastric ulcer	0.612	0.388
K62 Other diseases of anus and rectum	0.612	0.388
Z11 Special screening examination for infectious and parasitic diseases	0.609	0.391
Z10 Routine general health check-up of defined subpopulation	0.609	0.391
Z04 Examination and observation for other reasons	0.609	0.391
Z02 Examination and encounter for administrative purposes	0.609	0.391
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.609	0.391
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.609	0.391
Z80.0 Family history of malignant neoplasm of digestive organs	0.608	0.392
Z86.4 Personal history of psychoactive substance abuse	0.607	0.393
H40-H42 Glaucoma	0.607	0.393
I24 Other acute ischaemic heart diseases	0.606	0.394
I23 Certain current complications following acute myocardial infarction	0.606	0.394
I22 Subsequent myocardial infarction	0.606	0.394
Z39 Postpartum care and examination	0.602	0.398
Z38 Liveborn infants according to place of birth	0.602	0.398
Z36 Antenatal screening	0.602	0.398
Z35 Supervision of high-risk pregnancy	0.602	0.398
Z34 Supervision of normal pregnancy	0.602	0.398
Z32 Pregnancy examination and test	0.602	0.398
Z31 Procreative management	0.602	0.398
Z33 Pregnant state, incidental	0.602	0.398
R68 Other general symptoms and signs	0.601	0.399
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.601	0.399
R62 Lack of expected normal physiological development	0.601	0.399
R61 Hyperhidrosis	0.601	0.399
R60 Oedema, not elsewhere classified	0.601	0.399
R59 Enlarged lymph nodes	0.601	0.399
R57 Shock, not elsewhere classified	0.601	0.399
R56 Convulsions, not elsewhere classified	0.601	0.399
R52 Pain, not elsewhere classified	0.601	0.399
R64 Cachexia	0.601	0.399
R58 Haemorrhage, not elsewhere classified	0.601	0.399
R54 Senility	0.601	0.399
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.601	0.399
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.601	0.399
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.601	0.399
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.601	0.399
Z82.3 Family history of stroke	0.601	0.399
Z82.2 Family history of deafness and hearing loss	0.601	0.399
Z82.1 Family history of blindness and visual loss	0.601	0.399
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.601	0.399
G45 Transient cerebral ischaemic attacks and related syndromes	0.600	0.400
I20 Angina pectoris	0.599	0.401
I34 Nonrheumatic mitral valve disorders	0.598	0.401
Z30 Contraceptive management	0.597	0.403
I21 Acute myocardial infarction	0.595	0.404
K20 Oesophagitis	0.595	0.405
N99-N99 Other disorders of the genitourinary system	0.594	0.406
N70-N77 Inflammatory diseases of female pelvic organs	0.594	0.406
N60-N64 Disorders of breast	0.594	0.406
N25-N29 Other disorders of kidney and ureter	0.594	0.406
N20-N23 Urolithiasis	0.594	0.406
N10-N16 Renal tubulo-interstitial diseases	0.594	0.406
N00-N08 Glomerular diseases	0.594	0.406
H55-H59 Other disorders of eye and adnexa	0.594	0.406
H53-H54 Visual disturbances and blindness	0.594	0.406
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.594	0.406
H46-H48 Disorders of optic nerve and visual pathways	0.594	0.406
H43-H45 Disorders of vitreous body and globe	0.594	0.406
H30-H36 Disorders of choroid and retina	0.594	0.406
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.594	0.406
H10-H13 Disorders of conjunctiva	0.594	0.406
K28 Gastrojejunal ulcer	0.592	0.407
K27 Peptic ulcer, site unspecified	0.592	0.407
K26 Duodenal ulcer	0.592	0.407
K23 Disorders of oesophagus in diseases classified elsewhere	0.592	0.407
Z08 Follow-up examination after treatment for malignant neoplasm	0.591	0.408
D50-D53 Nutritional anaemias	0.590	0.410
I10 Essential (primary) hypertension	0.589	0.411
L03 Cellulitis	0.588	0.412
N81 Female genital prolapse	0.588	0.412
K44.1 Diaphragmatic hernia with gangrene	0.588	0.412
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.588	0.412
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.584	0.416
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.583	0.416
R03 Abnormal blood-pressure reading, without diagnosis	0.583	0.416
R01 Cardiac murmurs and other cardiac sounds	0.583	0.416
R05 Cough	0.583	0.416
R02 Gangrene, not elsewhere classified	0.583	0.416
R50 Fever of unknown origin	0.583	0.417
K29 Gastritis and duodenitis	0.583	0.417
N92.0 Excessive and frequent menstruation with regular cycle	0.582	0.418
R46 Symptoms and signs involving appearance and behaviour	0.579	0.421
R45 Symptoms and signs involving emotional state	0.579	0.421
R44 Other symptoms and signs involving general sensations and perceptions	0.579	0.421
R43 Disturbances of smell and taste	0.579	0.421
R40 Somnolence, stupor and coma	0.579	0.421
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.575	0.425
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.574	0.426
K59.9 Functional intestinal disorder, unspecified	0.572	0.428
K59.8 Other specified functional intestinal disorders	0.572	0.428
K59.4 Anal spasm	0.572	0.428
K59.3 Megacolon, not elsewhere classified	0.572	0.428
K59.2 Neurogenic bowel, not elsewhere classified	0.572	0.428
K59.1 Functional diarrhoea	0.572	0.428
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.571	0.428
K86 Other diseases of pancreas	0.571	0.428
K85 Acute pancreatitis	0.571	0.428
K83 Other diseases of biliary tract	0.571	0.428
K82 Other diseases of gallbladder	0.571	0.428
K81 Cholecystitis	0.571	0.428
Z92.3 Personal history of irradiation	0.570	0.430
D70-D77 Other diseases of blood and blood-forming organs	0.566	0.434
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.565	0.435
K65 Peritonitis	0.565	0.435
L82 Seborrhoeic keratosis	0.565	0.435
R07 Pain in throat and chest	0.565	0.435
Z87.8 Personal history of other specified conditions	0.564	0.436
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.564	0.436
Z87.6 Personal history of certain conditions arising in the perinatal period	0.564	0.436
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.564	0.436
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.564	0.436
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.564	0.436
Z87.0 Personal history of diseases of the respiratory system	0.564	0.436
L40 Psoriasis	0.563	0.437
Z60 Problems related to social environment	0.562	0.437
C43-C44 Melanoma and other malignant neoplasms of skin	0.561	0.438
N85 Other noninflammatory disorders of uterus, except cervix	0.561	0.439
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.560	0.440
Chapter X Diseases of the respiratory system	0.559	0.441
N18 Chronic renal failure	0.559	0.441
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.559	0.441
Z88.7 Personal history of allergy to serum and vaccine	0.559	0.441
Z88.5 Personal history of allergy to narcotic agent	0.559	0.441
Z88.4 Personal history of allergy to anaesthetic agent	0.559	0.441
Z88.3 Personal history of allergy to other anti-infective agents	0.559	0.441
Z88.2 Personal history of allergy to sulphonamides	0.559	0.441
I25.6 Silent myocardial ischaemia	0.558	0.442
I25.5 Ischaemic cardiomyopathy	0.558	0.442
I25.4 Coronary artery aneurysm	0.558	0.442
I25.3 Aneurysm of heart	0.558	0.442
I25.0 Atherosclerotic cardiovascular disease, so described	0.558	0.442
K30 Dyspepsia	0.558	0.442
R12 Heartburn	0.557	0.443
K22.1 Ulcer of oesophagus	0.556	0.444
Z40-Z54 Persons encountering health services for specific procedures and health care	0.556	0.444
K80.1 Calculus of gallbladder with other cholecystitis	0.554	0.446
I51 Complications and ill-defined descriptions of heart disease	0.553	0.447
R94 Abnormal results of function studies	0.552	0.448
Z09.0 Follow-up examination after surgery for other conditions	0.552	0.448
H26 Other cataract	0.552	0.448
Z09.8 Follow-up examination after other treatment for other conditions	0.552	0.448
R30-R39 Symptoms and signs involving the urinary system	0.551	0.449
R79 Other abnormal findings of blood chemistry	0.551	0.449
R41.0 Disorientation, unspecified	0.550	0.449
Z88.0 Personal history of allergy to penicillin	0.550	0.450
K58.9 Irritable bowel syndrome without diarrhoea	0.547	0.453
Z03.5 Observation for other suspected cardiovascular diseases	0.547	0.453
Z92.9 Personal history of medical treatment, unspecified	0.546	0.453
Z92.8 Personal history of other medical treatment	0.546	0.453
Z92.6 Personal history of chemotherapy for neoplastic disease	0.546	0.453
Z92.5 Personal history of rehabilitation measures	0.546	0.453
Z92.4 Personal history of major surgery, not elsewhere classified	0.546	0.453
Z92.0 Personal history of contraception	0.546	0.453
K42.9 Umbilical hernia without obstruction or gangrene	0.545	0.455
O60-O75 Complications of labour and delivery	0.545	0.455
Z80.9 Family history of malignant neoplasm, unspecified	0.544	0.456
Z80.8 Family history of malignant neoplasm of other organs or systems	0.544	0.456
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.544	0.456
Z80.6 Family history of leukaemia	0.544	0.456
Z80.5 Family history of malignant neoplasm of urinary tract	0.544	0.456
Z80.4 Family history of malignant neoplasm of genital organs	0.544	0.456
Z80.3 Family history of malignant neoplasm of breast	0.544	0.456
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.544	0.456
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.544	0.456
R63 Symptoms and signs concerning food and fluid intake	0.544	0.456
G47.3 Sleep apnoea	0.543	0.457
C50-C50 Malignant neoplasm of breast	0.543	0.457
I50 Heart failure	0.542	0.458
I80 Phlebitis and thrombophlebitis	0.542	0.458
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.542	0.458
L95 Vasculitis limited to skin, not elsewhere classified	0.542	0.458
L94 Other localised connective tissue disorders	0.542	0.458
L93 Lupus erythematosus	0.542	0.458
L92 Granulomatous disorders of skin and subcutaneous tissue	0.542	0.458
L91 Hypertrophic disorders of skin	0.542	0.458
L90 Atrophic disorders of skin	0.542	0.458
L89 Decubitus ulcer	0.542	0.458
L87 Transepidermal elimination disorders	0.542	0.458
L85 Other epidermal thickening	0.542	0.458
L81 Other disorders of pigmentation	0.542	0.458
L88 Pyoderma gangrenosum	0.542	0.458
L86 Keratoderma in diseases classified elsewhere	0.542	0.458
L84 Corns and callosities	0.542	0.458
L83 Acanthosis nigricans	0.542	0.458
L80 Vitiligo	0.542	0.458
D37-D48 Neoplasms of uncertain or unknown behaviour	0.540	0.460
D00-D09 In situ neoplasms	0.540	0.460
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.540	0.460
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.540	0.460
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.540	0.460
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.540	0.460
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.540	0.460
C64-C68 Malignant neoplasms of urinary tract	0.540	0.460
C51-C58 Malignant neoplasms of female genital organs	0.540	0.460
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.540	0.460
C40-C41 Malignant neoplasms of bone and articular cartilage	0.540	0.460
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.540	0.460
C15-C26 Malignant neoplasms of digestive organs	0.540	0.460
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.540	0.460
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.539	0.461
I88 Nonspecific lymphadenitis	0.539	0.461
I87 Other disorders of veins	0.539	0.461
I86 Varicose veins of other sites	0.539	0.461
I85 Oesophageal varices	0.539	0.461
I82 Other venous embolism and thrombosis	0.539	0.461
I81 Portal vein thrombosis	0.539	0.461
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.538	0.461
T79-T79 Certain early complications of trauma	0.538	0.461
T66-T78 Other and unspecified effects of external causes	0.538	0.461
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.538	0.461
T36-T50 Poisoning by drugs, medicaments and biological substances	0.538	0.461
T33-T35 Frostbite	0.538	0.461
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.538	0.461
T26-T28 Burns and corrosions confined to eye and internal organs	0.538	0.461
T20-T25 Burns and corrosions of external body surface, specified by site	0.538	0.461
T15-T19 Effects of foreign body entering through natural orifice	0.538	0.461
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.538	0.461
T00-T07 Injuries involving multiple body regions	0.538	0.461
S90-S99 Injuries to the ankle and foot	0.538	0.461
S80-S89 Injuries to the knee and lower leg	0.538	0.461
S70-S79 Injuries to the hip and thigh	0.538	0.461
S60-S69 Injuries to the wrist and hand	0.538	0.461
S50-S59 Injuries to the elbow and forearm	0.538	0.461
S40-S49 Injuries to the shoulder and upper arm	0.538	0.461
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.538	0.461
S20-S29 Injuries to the thorax	0.538	0.461
S10-S19 Injuries to the neck	0.538	0.461
S00-S09 Injuries to the head	0.538	0.461
I52 Other heart disorders in diseases classified elsewhere	0.538	0.461
I49 Other cardiac arrhythmias	0.538	0.461
I48 Atrial fibrillation and flutter	0.538	0.461
I47 Paroxysmal tachycardia	0.538	0.461
I46 Cardiac arrest	0.538	0.461
I45 Other conduction disorders	0.538	0.461
I44 Atrioventricular and left bundle-branch block	0.538	0.461
I43 Cardiomyopathy in diseases classified elsewhere	0.538	0.461
I42 Cardiomyopathy	0.538	0.461
I41 Myocarditis in diseases classified elsewhere	0.538	0.461
I40 Acute myocarditis	0.538	0.461
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.538	0.461
I37 Pulmonary valve disorders	0.538	0.461
I36 Nonrheumatic tricuspid valve disorders	0.538	0.461
I35 Nonrheumatic aortic valve disorders	0.538	0.461
I33 Acute and subacute endocarditis	0.538	0.461
I32 Pericarditis in diseases classified elsewhere	0.538	0.461
I31 Other diseases of pericardium	0.538	0.461
I30 Acute pericarditis	0.538	0.461
I38 Endocarditis, valve unspecified	0.538	0.461
I73 Other peripheral vascular diseases	0.536	0.464
D80-D89 Certain disorders involving the immune mechanism	0.536	0.464
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.536	0.464
D55-D59 Haemolytic anaemias	0.536	0.464
K01.1 Impacted teeth	0.536	0.464
G46 Vascular syndromes of brain in cerebrovascular diseases	0.535	0.464
G44 Other headache syndromes	0.535	0.464
G43 Migraine	0.535	0.464
G41 Status epilepticus	0.535	0.464
G40 Epilepsy	0.535	0.464
N98 Complications associated with artificial fertilisation	0.535	0.464
N97 Female infertility	0.535	0.464
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.535	0.464
N93 Other abnormal uterine and vaginal bleeding	0.535	0.464
N91 Absent, scanty and rare menstruation	0.535	0.464
N90 Other noninflammatory disorders of vulva and perineum	0.535	0.464
N89 Other noninflammatory disorders of vagina	0.535	0.464
N88 Other noninflammatory disorders of cervix uteri	0.535	0.464
N87 Dysplasia of cervix uteri	0.535	0.464
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.535	0.464
N82 Fistulae involving female genital tract	0.535	0.464
N80 Endometriosis	0.535	0.464
N96 Habitual aborter	0.535	0.464
N86 Erosion and ectropion of cervix uteri	0.535	0.464
K66.0 Peritoneal adhesions	0.534	0.466
Z88.6 Personal history of allergy to analgesic agent	0.534	0.466
N95 Menopausal and other perimenopausal disorders	0.534	0.466
Z90.7 Acquired absence of genital organ(s)	0.533	0.466
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.532	0.468
R00.0 Tachycardia, unspecified	0.531	0.468
Z65 Problems related to other psychosocial circumstances	0.530	0.470
Z64 Problems related to certain psychosocial circumstances	0.530	0.470
Z63 Other problems related to primary support group, including family circumstances	0.530	0.470
Z62 Other problems related to upbringing	0.530	0.470
Z61 Problems related to negative life events in childhood	0.530	0.470
Z59 Problems related to housing and economic circumstances	0.530	0.470
Z58 Problems related to physical environment	0.530	0.470
Z57 Occupational exposure to risk-factors	0.530	0.470
Z56 Problems related to employment and unemployment	0.530	0.470
Z55 Problems related to education and literacy	0.530	0.470
I15 Secondary hypertension	0.529	0.471
I13 Hypertensive heart and renal disease	0.529	0.471
I12 Hypertensive renal disease	0.529	0.471
I11 Hypertensive heart disease	0.529	0.471
N84 Polyp of female genital tract	0.529	0.471
R06.0 Dyspnoea	0.528	0.472
Z37.9 Outcome of delivery unspecified	0.527	0.472
Z37.7 Other multiple births, all stillborn	0.527	0.472
Z37.6 Other multiple births, some liveborn	0.527	0.472
Z37.5 Other multiple births, all liveborn	0.527	0.472
Z37.4 Twins, both stillborn	0.527	0.472
Z37.3 Twins, one liveborn and one stillborn	0.527	0.472
Z37.2 Twins, both liveborn	0.527	0.472
Z37.1 Single stillbirth	0.527	0.472
O94-O99 Other obstetric conditions, not elsewhere classified	0.526	0.474
O85-O92 Complications predominantly related to the puerperium	0.526	0.474
O80-O84 Delivery	0.526	0.474
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.526	0.474
O20-O29 Other maternal disorders predominantly related to pregnancy	0.526	0.474
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.526	0.474
O00-O08 Pregnancy with abortive outcome	0.526	0.474
K02.8 Other dental caries	0.524	0.476
K02.5 Caries with pulp exposure	0.524	0.476
K02.4 Odontoclasia	0.524	0.476

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations