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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17023661
log Bayes Factor = 2.09285
Chromosome 3   position 86,968,509  (GRCh37) Explore rs17023661 on Ensembl!
Variant rs17023661 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
0.991 0.009 0.000
H25-H28 Disorders of lens
0.989 0.011 0.000
H26 Other cataract
0.986 0.014 0.000
H26.9 Cataract, unspecified
0.985 0.015 0.000
# Top node
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.948 0.052 0.000
J20-J22 Other acute lower respiratory infections
0.948 0.052 0.000
Chapter V Mental and behavioural disorders
0.943 0.057 0.000
J22 Unspecified acute lower respiratory infection
0.933 0.067 0.000
H40-H42 Glaucoma
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.889 0.111 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.887 0.113 0.000
H40 Glaucoma
0.886 0.114 0.000
H33 Retinal detachments and breaks
0.885 0.115 0.000
J95-J99 Other diseases of the respiratory system
0.866 0.134 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.865 0.135 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.858 0.142 0.000
F30-F39 Mood [affective] disorders
0.855 0.145 0.000
H25 Senile cataract
0.850 0.150 0.000
Chapter VIII Diseases of the ear and mastoid process
0.831 0.169 0.000
H40.9 Glaucoma, unspecified
0.822 0.178 0.000
H43-H45 Disorders of vitreous body and globe
0.821 0.179 0.000
H35 Other retinal disorders
0.819 0.181 0.000
J09-J18 Influenza and pneumonia
0.809 0.191 0.000
H33.3 Retinal breaks without detachment
0.801 0.199 0.000
Chapter I Certain infectious and parasitic diseases
0.799 0.201 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.797 0.203 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.795 0.205 0.000
J98 Other respiratory disorders
0.791 0.209 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.784 0.216 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.219 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.775 0.225 0.000
F32 Depressive episode
0.771 0.229 0.000
H40.1 Primary open-angle glaucoma
0.769 0.231 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.764 0.236 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.758 0.242 0.000
J90-J94 Other diseases of pleura
0.757 0.243 0.000
J60-J70 Lung diseases due to external agents
0.748 0.252 0.000
H33.2 Serous retinal detachment
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.741 0.259 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.740 0.259 0.000
G40 Epilepsy
0.740 0.260 0.000
F10.1 Harmful use
0.731 0.269 0.000
J98.1 Pulmonary collapse
0.726 0.274 0.000
J00-J06 Acute upper respiratory infections
0.726 0.274 0.000
H25.1 Senile nuclear cataract
0.723 0.277 0.000
H53-H54 Visual disturbances and blindness
0.721 0.279 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.716 0.284 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.713 0.287 0.000
H34 Retinal vascular occlusions
0.712 0.288 0.000
H65-H75 Diseases of middle ear and mastoid
0.711 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.711 0.289 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.711 0.289 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.711 0.289 0.000
H10-H13 Disorders of conjunctiva
0.711 0.289 0.000
G40.9 Epilepsy, unspecified
0.711 0.289 0.000
F32.9 Depressive episode, unspecified
0.710 0.290 0.000
H35.3 Degeneration of macula and posterior pole
0.709 0.291 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.709 0.291 0.000
H27 Other disorders of lens
0.709 0.291 0.000
H26.8 Other specified cataract
0.707 0.293 0.000
H26.3 Drug-induced cataract
0.707 0.293 0.000
H26.2 Complicated cataract
0.707 0.293 0.000
H26.1 Traumatic cataract
0.707 0.293 0.000
H26.0 Infantile, juvenile and presenile cataract
0.707 0.293 0.000
Chapter IX Diseases of the circulatory system
0.705 0.295 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.701 0.299 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.701 0.299 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.701 0.299 0.000
H43 Disorders of vitreous body
0.700 0.300 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.698 0.302 0.000
J40-J47 Chronic lower respiratory diseases
0.698 0.302 0.000
Chapter XX External causes of morbidity and mortality
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.695 0.305 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.695 0.305 0.000
J18 Pneumonia, organism unspecified
0.694 0.306 0.000
B95-B98 Bacterial, viral and other infectious agents
0.690 0.310 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.682 0.318 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.680 0.320 0.000
H31 Other disorders of choroid
0.680 0.320 0.000
H30 Chorioretinal inflammation
0.680 0.320 0.000
J21 Acute bronchiolitis
0.680 0.320 0.000
J20 Acute bronchitis
0.680 0.320 0.000
H25.8 Other senile cataract
0.678 0.322 0.000
F99-F99 Unspecified mental disorder
0.676 0.324 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.676 0.324 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
F70-F79 Mental retardation
0.676 0.324 0.000
F60-F69 Disorders of adult personality and behaviour
0.676 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.676 0.324 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.673 0.327 0.000
H42 Glaucoma in diseases classified elsewhere
0.666 0.333 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
G62 Other polyneuropathies
0.664 0.336 0.000
H40.2 Primary angle-closure glaucoma
0.663 0.337 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.662 0.338 0.000
L03 Cellulitis
0.656 0.344 0.000
H00 Hordeolum and chalazion
0.656 0.344 0.000
A30-A49 Other bacterial diseases
0.655 0.345 0.000
F31 Bipolar affective disorder
0.654 0.346 0.000
L60-L75 Disorders of skin appendages
0.653 0.347 0.000
L20-L30 Dermatitis and eczema
0.650 0.350 0.000
T66-T78 Other and unspecified effects of external causes
0.650 0.350 0.000
H33.0 Retinal detachment with retinal break
0.649 0.351 0.000
I30-I52 Other forms of heart disease
0.648 0.352 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
S80-S89 Injuries to the knee and lower leg
0.642 0.358 0.000
H36 Retinal disorders in diseases classified elsewhere
0.641 0.359 0.000
S50-S59 Injuries to the elbow and forearm
0.641 0.359 0.000
F33 Recurrent depressive disorder
0.640 0.359 0.000
J18.9 Pneumonia, unspecified
0.640 0.360 0.000
H90-H95 Other disorders of ear
0.639 0.361 0.000
G70-G73 Diseases of myoneural junction and muscle
0.637 0.362 0.000
G30-G32 Other degenerative diseases of the nervous system
0.637 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.637 0.362 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.637 0.362 0.000
L50-L54 Urticaria and erythema
0.636 0.364 0.000
L10-L14 Bullous disorders
0.636 0.364 0.000
H40.8 Other glaucoma
0.635 0.365 0.000
H40.6 Glaucoma secondary to drugs
0.635 0.365 0.000
H40.5 Glaucoma secondary to other eye disorders
0.635 0.365 0.000
H40.4 Glaucoma secondary to eye inflammation
0.635 0.365 0.000
H40.3 Glaucoma secondary to eye trauma
0.635 0.365 0.000
S60-S69 Injuries to the wrist and hand
0.635 0.365 0.000
H33.5 Other retinal detachments
0.635 0.365 0.000
H33.4 Traction detachment of retina
0.635 0.365 0.000
H33.1 Retinoschisis and retinal cysts
0.635 0.365 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.632 0.368 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.630 0.370 0.000
H26.4 After-cataract
0.629 0.371 0.000
L82 Seborrhoeic keratosis
0.627 0.373 0.000
S40-S49 Injuries to the shoulder and upper arm
0.627 0.373 0.000
H04 Disorders of lachrymal system
0.624 0.376 0.000
F10.3 Withdrawal state
0.622 0.378 0.000
H35.8 Other specified retinal disorders
0.622 0.378 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.621 0.379 0.000
J96 Respiratory failure, not elsewhere classified
0.621 0.379 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.621 0.379 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.620 0.380 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.620 0.380 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.620 0.380 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.620 0.380 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.620 0.380 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.620 0.380 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.620 0.380 0.000
F11 Mental and behavioural disorders due to use of opioids
0.620 0.380 0.000
H52 Disorders of refraction and accommodation
0.620 0.380 0.000
J92 Pleural plaque
0.615 0.385 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.615 0.385 0.000
T79-T79 Certain early complications of trauma
0.615 0.385 0.000
T33-T35 Frostbite
0.615 0.385 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.615 0.385 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.615 0.385 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.615 0.385 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.615 0.385 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.615 0.385 0.000
T00-T07 Injuries involving multiple body regions
0.615 0.385 0.000
S90-S99 Injuries to the ankle and foot
0.615 0.385 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.615 0.385 0.000
S20-S29 Injuries to the thorax
0.615 0.385 0.000
S10-S19 Injuries to the neck
0.615 0.385 0.000
F38 Other mood [affective] disorders
0.613 0.387 0.000
F34 Persistent mood [affective] disorders
0.613 0.387 0.000
F30 Manic episode
0.613 0.387 0.000
F39 Unspecified mood [affective] disorder
0.613 0.387 0.000
G90-G99 Other disorders of the nervous system
0.609 0.391 0.000
H25.2 Senile cataract, morgagnian type
0.609 0.391 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.607 0.393 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.606 0.394 0.000
S00-S09 Injuries to the head
0.605 0.395 0.000
F10.2 Dependence syndrome
0.597 0.403 0.000
H25.9 Senile cataract, unspecified
0.596 0.403 0.000
G62.9 Polyneuropathy, unspecified
0.596 0.404 0.000
H72 Perforation of tympanic membrane
0.596 0.404 0.000
L08 Other local infections of skin and subcutaneous tissue
0.596 0.404 0.000
H60-H62 Diseases of external ear
0.596 0.404 0.000
H25.0 Senile incipient cataract
0.595 0.404 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.593 0.407 0.000
J69 Pneumonitis due to solids and liquids
0.589 0.411 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.589 0.411 0.000
H44 Disorders of globe
0.589 0.411 0.000
H35.9 Retinal disorder, unspecified
0.587 0.413 0.000
H35.7 Separation of retinal layers
0.587 0.413 0.000
H35.6 Retinal haemorrhage
0.587 0.413 0.000
H35.5 Hereditary retinal dystrophy
0.587 0.413 0.000
H35.4 Peripheral retinal degeneration
0.587 0.413 0.000
H35.2 Other proliferative retinopathy
0.587 0.413 0.000
H35.1 Retinopathy of prematurity
0.587 0.413 0.000
H35.0 Background retinopathy and retinal vascular changes
0.587 0.413 0.000
G81 Hemiplegia
0.587 0.413 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.586 0.414 0.000
H40.0 Glaucoma suspect
0.585 0.415 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.585 0.415 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.584 0.416 0.000
J47 Bronchiectasis
0.583 0.417 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.582 0.418 0.000
J17 Pneumonia in diseases classified elsewhere
0.580 0.420 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.580 0.420 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.580 0.420 0.000
J12 Viral pneumonia, not elsewhere classified
0.580 0.420 0.000
J11 Influenza, virus not identified
0.580 0.420 0.000
J10 Influenza due to identified influenza virus
0.580 0.420 0.000
J14 Pneumonia due to Haemophilus influenzae
0.580 0.420 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.580 0.420 0.000
J09 Influenza due to certain identified influenza virus
0.580 0.420 0.000
H80-H83 Diseases of inner ear
0.580 0.420 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.577 0.423 0.000
H43.3 Other vitreous opacities
0.575 0.425 0.000
I05-I09 Chronic rheumatic heart diseases
0.575 0.425 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.574 0.426 0.000
B99-B99 Other infectious diseases
0.573 0.427 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.573 0.427 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.573 0.427 0.000
B65-B83 Helminthiases
0.573 0.427 0.000
B50-B64 Protozoal diseases
0.573 0.427 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.573 0.427 0.000
B15-B19 Viral hepatitis
0.573 0.427 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.573 0.427 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.573 0.427 0.000
A80-A89 Viral infections of the central nervous system
0.573 0.427 0.000
A75-A79 Rickettsioses
0.573 0.427 0.000
A70-A74 Other diseases caused by chlamydiae
0.573 0.427 0.000
A65-A69 Other spirochaetal diseases
0.573 0.427 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.573 0.427 0.000
A20-A28 Certain zoonotic bacterial diseases
0.573 0.427 0.000
A15-A19 Tuberculosis
0.573 0.427 0.000
G20-G26 Extrapyramidal and movement disorders
0.573 0.427 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.572 0.428 0.000
J40 Bronchitis, not specified as acute or chronic
0.571 0.429 0.000
F10.9 Unspecified mental and behavioural disorder
0.571 0.429 0.000
F10.8 Other mental and behavioural disorders
0.571 0.429 0.000
F10.7 Residual and late-onset psychotic disorder
0.571 0.429 0.000
F10.6 Amnesic syndrome
0.571 0.429 0.000
F10.5 Psychotic disorder
0.571 0.429 0.000
F10.4 Withdrawal state with delirium
0.571 0.429 0.000
L05 Pilonidal cyst
0.570 0.430 0.000
L04 Acute lymphadenitis
0.570 0.430 0.000
L01 Impetigo
0.570 0.430 0.000
L00 Staphylococcal scalded skin syndrome
0.570 0.430 0.000
J98.9 Respiratory disorder, unspecified
0.567 0.433 0.000
J98.8 Other specified respiratory disorders
0.567 0.433 0.000
J98.6 Disorders of diaphragm
0.567 0.433 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.567 0.433 0.000
J98.3 Compensatory emphysema
0.567 0.433 0.000
J98.2 Interstitial emphysema
0.567 0.433 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.565 0.435 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.564 0.436 0.000
H00.1 Chalazion
0.564 0.436 0.000
B35-B49 Mycoses
0.564 0.436 0.000
H43.1 Vitreous haemorrhage
0.563 0.436 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.562 0.438 0.000
H05 Disorders of orbit
0.562 0.438 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.562 0.438 0.000
H01 Other inflammation of eyelid
0.562 0.438 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.560 0.440 0.000
G44 Other headache syndromes
0.560 0.440 0.000
G41 Status epilepticus
0.560 0.440 0.000
H65 Nonsuppurative otitis media
0.560 0.440 0.000
G47 Sleep disorders
0.556 0.444 0.000
H51 Other disorders of binocular movement
0.556 0.444 0.000
H50 Other strabismus
0.556 0.444 0.000
H49 Paralytic strabismus
0.556 0.444 0.000
G35 Multiple sclerosis
0.555 0.444 0.000
F17.2 Dependence syndrome
0.555 0.445 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.554 0.446 0.000
L81 Other disorders of pigmentation
0.553 0.447 0.000
F32.8 Other depressive episodes
0.552 0.447 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.552 0.447 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.552 0.447 0.000
F32.1 Moderate depressive episode
0.552 0.447 0.000
F32.0 Mild depressive episode
0.552 0.447 0.000
A41 Other septicaemia
0.552 0.448 0.000
F10.0 Acute intoxication
0.552 0.448 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.548 0.452 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.548 0.452 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.548 0.452 0.000
L94 Other localised connective tissue disorders
0.548 0.452 0.000
L93 Lupus erythematosus
0.548 0.452 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.548 0.452 0.000
L89 Decubitus ulcer
0.548 0.452 0.000
L87 Transepidermal elimination disorders
0.548 0.452 0.000
L85 Other epidermal thickening
0.548 0.452 0.000
L88 Pyoderma gangrenosum
0.548 0.452 0.000
L86 Keratoderma in diseases classified elsewhere
0.548 0.452 0.000
L84 Corns and callosities
0.548 0.452 0.000
L83 Acanthosis nigricans
0.548 0.452 0.000
L80 Vitiligo
0.548 0.452 0.000
L40-L45 Papulosquamous disorders
0.548 0.452 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.543 0.457 0.000
G61 Inflammatory polyneuropathy
0.543 0.457 0.000
G60 Hereditary and idiopathic neuropathy
0.543 0.457 0.000
G64 Other disorders of peripheral nervous system
0.543 0.457 0.000
F03 Unspecified dementia
0.543 0.457 0.000
J94 Other pleural conditions
0.542 0.457 0.000
J93 Pneumothorax
0.542 0.457 0.000
J91 Pleural effusion in conditions classified elsewhere
0.542 0.457 0.000
H34.8 Other retinal vascular occlusions
0.542 0.458 0.000
L03.1 Cellulitis of other parts of limb
0.540 0.460 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.538 0.462 0.000
D60-D64 Aplastic and other anaemias
0.537 0.463 0.000
J70 Respiratory conditions due to other external agents
0.536 0.464 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.536 0.464 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.536 0.464 0.000
J66 Airway disease due to specific organic dust
0.536 0.464 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.536 0.464 0.000
J62 Pneumoconiosis due to dust containing silica
0.536 0.464 0.000
J65 Pneumoconiosis associated with tuberculosis
0.536 0.464 0.000
J64 Unspecified pneumoconiosis
0.536 0.464 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.536 0.464 0.000
J60 Coalworker's pneumoconiosis
0.536 0.464 0.000
L91 Hypertrophic disorders of skin
0.535 0.465 0.000
J98.4 Other disorders of lung
0.535 0.465 0.000
I50 Heart failure
0.535 0.465 0.000
I60-I69 Cerebrovascular diseases
0.534 0.466 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.534 0.466 0.000
I42 Cardiomyopathy
0.532 0.468 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.531 0.469 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.531 0.469 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.531 0.469 0.000
F02 Dementia in other diseases classified elsewhere
0.531 0.469 0.000
F01 Vascular dementia
0.531 0.469 0.000
F00 Dementia in Alzheimer's disease
0.531 0.469 0.000
F09 Unspecified organic or symptomatic mental disorder
0.531 0.469 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.531 0.469 0.000
G40.8 Other epilepsy
0.530 0.469 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.530 0.469 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.530 0.469 0.000
G40.5 Special epileptic syndromes
0.530 0.469 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.530 0.469 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.530 0.469 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.530 0.469 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.530 0.469 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.530 0.469 0.000
I77 Other disorders of arteries and arterioles
0.530 0.470 0.000
L90 Atrophic disorders of skin
0.529 0.470 0.000
H53 Visual disturbances
0.527 0.473 0.000
I38 Endocarditis, valve unspecified
0.526 0.474 0.000
J90 Pleural effusion, not elsewhere classified
0.525 0.475 0.000
T51 Toxic effect of alcohol
0.525 0.475 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.523 0.477 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.522 0.478 0.000
I71 Aortic aneurysm and dissection
0.522 0.478 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.521 0.479 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.520 0.479 0.000
J04 Acute laryngitis and tracheitis
0.520 0.479 0.000
J03 Acute tonsillitis
0.520 0.479 0.000
J01 Acute sinusitis
0.520 0.479 0.000
J00 Acute nasopharyngitis [common cold]
0.520 0.479 0.000
V10-V19 Pedal cyclist injured in transport accident
0.517 0.483 0.000
H54 Blindness and low vision
0.517 0.483 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.516 0.484 0.000
I31 Other diseases of pericardium
0.516 0.484 0.000
J92.9 Pleural plaque without asbestos
0.514 0.486 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.514 0.486 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.514 0.486 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.514 0.486 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.514 0.486 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.514 0.486 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.514 0.486 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.514 0.486 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.514 0.486 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.514 0.486 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.514 0.486 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.514 0.486 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.514 0.486 0.000
T36 Poisoning by systemic antibiotics
0.514 0.486 0.000
W00-W19 Falls
0.512 0.488 0.000
G83 Other paralytic syndromes
0.511 0.489 0.000
G82 Paraplegia and tetraplegia
0.511 0.489 0.000
G80 Infantile cerebral palsy
0.511 0.489 0.000
H04.2 Epiphora
0.511 0.489 0.000
H34.9 Retinal vascular occlusion, unspecified
0.510 0.490 0.000
H34.2 Other retinal artery occlusions
0.510 0.490 0.000
H34.1 Central retinal artery occlusion
0.510 0.490 0.000
H34.0 Transient retinal artery occlusion
0.510 0.490 0.000
F31.9 Bipolar affective disorder, unspecified
0.510 0.490 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.510 0.490 0.000
H74 Other disorders of middle ear and mastoid
0.510 0.490 0.000
H73 Other disorders of tympanic membrane
0.510 0.490 0.000
H70 Mastoiditis and related conditions
0.510 0.490 0.000
H69 Other disorders of Eustachian tube
0.510 0.490 0.000
H68 Eustachian salpingitis and obstruction
0.510 0.490 0.000
H67 Otitis media in diseases classified elsewhere
0.510 0.490 0.000
H66 Suppurative and unspecified otitis media
0.510 0.490 0.000
H71 Cholesteatoma of middle ear
0.510 0.490 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.509 0.490 0.000
H11 Other disorders of conjunctiva
0.509 0.490 0.000
H10 Conjunctivitis
0.509 0.490 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.509 0.490 0.000
H21 Other disorders of iris and ciliary body
0.509 0.490 0.000
H20 Iridocyclitis
0.509 0.490 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.509 0.490 0.000
H18 Other disorders of cornea
0.509 0.490 0.000
H17 Corneal scars and opacities
0.509 0.490 0.000
H16 Keratitis
0.509 0.490 0.000
H15 Disorders of sclera
0.509 0.490 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.509 0.490 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.509 0.490 0.000
H46 Optic neuritis
0.509 0.490 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.509 0.490 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.509 0.490 0.000
H57 Other disorders of eye and adnexa
0.509 0.490 0.000
H55 Nystagmus and other irregular eye movements
0.509 0.490 0.000
H52.1 Myopia
0.509 0.491 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.509 0.491 0.000
B25-B34 Other viral diseases
0.508 0.491 0.000
H27.9 Disorder of lens, unspecified
0.508 0.491 0.000
H27.8 Other specified disorders of lens
0.508 0.491 0.000
H27.1 Dislocation of lens
0.508 0.491 0.000
H27.0 Aphakia
0.508 0.491 0.000
H28.8 Other disorders of lens in diseases classified elsewhere
0.508 0.491 0.000
H28.2 Cataract in other diseases classified elsewhere
0.508 0.491 0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.508 0.491 0.000
H28.0 Diabetic cataract
0.508 0.491 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.507 0.493 0.000
I00-I02 Acute rheumatic fever
0.505 0.495 0.000
J84 Other interstitial pulmonary diseases
0.504 0.496 0.000
J02 Acute pharyngitis
0.503 0.497 0.000
O85-O92 Complications predominantly related to the puerperium
0.502 0.497 0.000
P90-P96 Other disorders originating in the perinatal period
0.502 0.497 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.502 0.497 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.502 0.497 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.502 0.497 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.502 0.497 0.000
P35-P39 Infections specific to the perinatal period
0.502 0.497 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.502 0.497 0.000
P10-P15 Birth trauma
0.502 0.497 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.502 0.497 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.502 0.497 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.502 0.497 0.000
Q80-Q89 Other congenital malformations
0.502 0.497 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.502 0.497 0.000
Q60-Q64 Congenital malformations of the urinary system
0.502 0.497 0.000
Q50-Q56 Congenital malformations of genital organs
0.502 0.497 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.502 0.497 0.000
Q35-Q37 Cleft lip and cleft palate
0.502 0.497 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.502 0.497 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.502 0.497 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.502 0.497 0.000
Q00-Q07 Congenital malformations of the nervous system
0.502 0.497 0.000
L27 Dermatitis due to substances taken internally
0.502 0.498 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.502 0.498 0.000
H43.9 Disorder of vitreous body, unspecified
0.502 0.498 0.000
H43.2 Crystalline deposits in vitreous body
0.502 0.498 0.000
H43.0 Vitreous prolapse
0.502 0.498 0.000
I51 Complications and ill-defined descriptions of heart disease
0.501 0.499 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.501 0.499 0.000
J81 Pulmonary oedema
0.501 0.499 0.000
J80 Adult respiratory distress syndrome
0.501 0.499 0.000
T78 Adverse effects, not elsewhere classified
0.500 0.499 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.500 0.500 0.000
J41 Simple and mucopurulent chronic bronchitis
0.500 0.500 0.000
J46 Status asthmaticus
0.500 0.500 0.000
J42 Unspecified chronic bronchitis
0.500 0.500 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.500 0.500 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.500 0.500 0.000
Y35-Y36 Legal intervention and operations of war
0.500 0.500 0.000
Y10-Y34 Event of undetermined intent
0.500 0.500 0.000
Y00-Y09 Assault
0.500 0.500 0.000
X85-X99 Assault
0.500 0.500 0.000
X60-X84 Intentional self-harm
0.500 0.500 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.500 0.500 0.000
X50-X57 Overexertion, travel and privation
0.500 0.500 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.500 0.500 0.000
X30-X39 Exposure to forces of nature
0.500 0.500 0.000
X20-X29 Contact with venomous animals and plants
0.500 0.500 0.000
X10-X19 Contact with heat and hot substances
0.500 0.500 0.000
X00-X09 Exposure to smoke, fire and flames
0.500 0.500 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.500 0.500 0.000
W75-W84 Other accidental threats to breathing
0.500 0.500 0.000
W65-W74 Accidental drowning and submersion
0.500 0.500 0.000
W50-W64 Exposure to animate mechanical forces
0.500 0.500 0.000
W20-W49 Exposure to inanimate mechanical forces
0.500 0.500 0.000
V98-V99 Other and unspecified transport accidents
0.500 0.500 0.000
V95-V97 Air and space transport accidents
0.500 0.500 0.000
V90-V94 Water transport accidents
0.500 0.500 0.000
V80-V89 Other land transport accidents
0.500 0.500 0.000
V70-V79 Bus occupant injured in transport accident
0.500 0.500 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.500 0.500 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.500 0.500 0.000
V40-V49 Car occupant injured in transport accident
0.500 0.500 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.500 0.500 0.000
V20-V29 Motorcycle rider injured in transport accident
0.500 0.500 0.000
V01-V09 Pedestrian injured in transport accident
0.500 0.500 0.000
O00-O08 Pregnancy with abortive outcome
0.499 0.500 0.000
H90 Conductive and sensorineural hearing loss
0.499 0.500 0.000
H43.8 Other disorders of vitreous body
0.499 0.501 0.000
J86 Pyothorax
0.498 0.501 0.000
J85 Abscess of lung and mediastinum
0.498 0.501 0.000
G37 Other demyelinating diseases of central nervous system
0.498 0.502 0.000
G36 Other acute disseminated demyelination
0.498 0.502 0.000
J18.8 Other pneumonia, organism unspecified
0.498 0.502 0.000
J18.2 Hypostatic pneumonia, unspecified
0.498 0.502 0.000
J18.0 Bronchopneumonia, unspecified
0.498 0.502 0.000
I34 Nonrheumatic mitral valve disorders
0.497 0.502 0.000
G81.9 Hemiplegia, unspecified
0.497 0.503 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.494 0.505 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.493 0.507 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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