TreeWAS – Variant ID: rs1704996

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
J43 Emphysema	0.998	0.002	0.000
J43.9 Emphysema, unspecified	0.997	0.003	0.000
M05 Seropositive rheumatoid arthritis	0.996	0.004	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.994	0.006	0.000
J47 Bronchiectasis	0.992	0.008	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.990	0.010	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.990	0.010	0.000
E03 Other hypothyroidism	0.974	0.026	0.000
M13 Other arthritis	0.959	0.041	0.000
M70-M79 Other soft tissue disorders	0.955	0.045	0.000
M20-M25 Other joint disorders	0.949	0.051	0.000
E00-E07 Disorders of thyroid gland	0.941	0.059	0.000
# Top node	0.936	0.064	0.000
Chapter X Diseases of the respiratory system	0.936	0.064	0.000
Chapter II Neoplasms	0.933	0.067	0.000
C15-C26 Malignant neoplasms of digestive organs	0.933	0.067	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.930	0.070	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.929	0.071	0.000
M35 Other systemic involvement of connective tissue	0.929	0.071	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.929	0.071	0.000
M13.9 Arthritis, unspecified	0.929	0.071	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.927	0.073	0.000
C34 Malignant neoplasm of bronchus and lung	0.924	0.076	0.000
C34.9 Bronchus or lung, unspecified	0.920	0.080	0.000
M35.3 Polymyalgia rheumatica	0.919	0.081	0.000
C16 Malignant neoplasm of stomach	0.908	0.092	0.000
M06.3 Rheumatoid nodule	0.900	0.100	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.899	0.101	0.000
C18 Malignant neoplasm of colon	0.892	0.108	0.000
D00-D09 In situ neoplasms	0.883	0.117	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.882	0.118	0.000
M79.8 Other specified soft tissue disorders	0.874	0.126	0.000
C21 Malignant neoplasm of anus and anal canal	0.870	0.130	0.000
M40-M43 Deforming dorsopathies	0.866	0.134	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.863	0.137	0.000
M12 Other specific arthropathies	0.861	0.139	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.850	0.150	0.000
M50-M54 Other dorsopathies	0.842	0.158	0.000
C18.3 Hepatic flexure	0.842	0.158	0.000
M77 Other enthesopathies	0.835	0.165	0.000
C32 Malignant neoplasm of larynx	0.827	0.173	0.000
C16.9 Stomach, unspecified	0.825	0.175	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.819	0.181	0.000
M54.3 Sciatica	0.819	0.181	0.000
C16.0 Cardia	0.818	0.182	0.000
M54 Dorsalgia	0.817	0.183	0.000
M54.39 Sciatica (Site unspecified)	0.816	0.184	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.815	0.185	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.814	0.186	0.000
M31 Other necrotising vasculopathies	0.813	0.187	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.809	0.191	0.000
C18.6 Descending colon	0.806	0.194	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.800	0.200	0.000
J95-J99 Other diseases of the respiratory system	0.799	0.201	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.795	0.205	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.794	0.206	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.785	0.215	0.000
M91-M94 Chondropathies	0.785	0.215	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.784	0.216	0.000
M60-M63 Disorders of muscles	0.781	0.218	0.000
E04 Other non-toxic goitre	0.781	0.219	0.000
M06.4 Inflammatory polyarthropathy	0.779	0.221	0.000
M24 Other specific joint derangements	0.776	0.224	0.000
M11 Other crystal arthropathies	0.775	0.225	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.775	0.225	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.772	0.228	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.771	0.229	0.000
M06.0 Seronegative rheumatoid arthritis	0.769	0.231	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.769	0.231	0.000
C21.1 Anal canal	0.768	0.232	0.000
M65-M68 Disorders of synovium and tendon	0.762	0.237	0.000
S20-S29 Injuries to the thorax	0.762	0.238	0.000
M12.3 Palindromic rheumatism	0.761	0.239	0.000
C21.0 Anus, unspecified	0.760	0.240	0.000
J45.0 Predominantly allergic asthma	0.757	0.243	0.000
Chapter V Mental and behavioural disorders	0.755	0.245	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.754	0.246	0.000
C18.7 Sigmoid colon	0.753	0.247	0.000
M10 Gout	0.753	0.247	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.752	0.248	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.751	0.249	0.000
C16.5 Lesser curvature of stomach, unspecified	0.751	0.249	0.000
C34.3 Lower lobe, bronchus or lung	0.750	0.250	0.000
E20-E35 Disorders of other endocrine glands	0.749	0.251	0.000
M86-M90 Other osteopathies	0.747	0.253	0.000
D06 Carcinoma in situ of cervix uteri	0.742	0.258	0.000
E03.8 Other specified hypothyroidism	0.741	0.259	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.741	0.259	0.000
M06.34 Rheumatoid nodule (Hand)	0.741	0.259	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.741	0.259	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.739	0.261	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.737	0.263	0.000
M79.6 Pain in limb	0.733	0.267	0.000
C32.0 Glottis	0.729	0.271	0.000
M35.1 Other overlap syndromes	0.728	0.272	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.727	0.273	0.000
M41 Scoliosis	0.725	0.275	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.724	0.276	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.723	0.277	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.722	0.278	0.000
T79-T79 Certain early complications of trauma	0.722	0.278	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.720	0.280	0.000
M72 Fibroblastic disorders	0.718	0.282	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283	0.000
J45.8 Mixed asthma	0.717	0.283	0.000
J45.1 Nonallergic asthma	0.717	0.283	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283	0.000
J43.8 Other emphysema	0.715	0.284	0.000
J43.2 Centrilobular emphysema	0.715	0.284	0.000
J43.1 Panlobular emphysema	0.715	0.284	0.000
J43.0 MacLeod's syndrome	0.715	0.284	0.000
S50-S59 Injuries to the elbow and forearm	0.715	0.285	0.000
M05.8 Other seropositive rheumatoid arthritis	0.714	0.286	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.714	0.286	0.000
M05.2 Rheumatoid vasculitis	0.714	0.286	0.000
M05.1 Rheumatoid lung disease	0.714	0.286	0.000
M05.0 Felty's syndrome	0.714	0.286	0.000
M76 Enthesopathies of lower limb, excluding foot	0.714	0.286	0.000
M77.4 Metatarsalgia	0.713	0.287	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.713	0.287	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.713	0.287	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.713	0.287	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.713	0.287	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.713	0.287	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.713	0.287	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.713	0.287	0.000
Q60-Q64 Congenital malformations of the urinary system	0.709	0.291	0.000
M40 Kyphosis and lordosis	0.705	0.295	0.000
C15 Malignant neoplasm of oesophagus	0.704	0.296	0.000
M22 Disorders of patella	0.702	0.298	0.000
M30 Polyarteritis nodosa and related conditions	0.700	0.300	0.000
E03.5 Myxoedema coma	0.698	0.302	0.000
E03.4 Atrophy of thyroid (acquired)	0.698	0.302	0.000
E03.3 Postinfectious hypothyroidism	0.698	0.302	0.000
E03.1 Congenital hypothyroidism without goitre	0.698	0.302	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.698	0.302	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.697	0.303	0.000
M13.0 Polyarthritis, unspecified	0.696	0.304	0.000
Q50-Q56 Congenital malformations of genital organs	0.695	0.305	0.000
M34 Systemic sclerosis	0.695	0.305	0.000
J46 Status asthmaticus	0.695	0.305	0.000
D02.0 Larynx	0.693	0.307	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.692	0.308	0.000
M13.93 Arthritis, unspecified (Forearm)	0.691	0.309	0.000
M13.8 Other specified arthritis	0.687	0.312	0.000
M13.1 Monoarthritis, not elsewhere classified	0.687	0.312	0.000
D03 Melanoma in situ	0.686	0.314	0.000
M00-M03 Infectious arthropathies	0.685	0.315	0.000
D09 Carcinoma in situ of other and unspecified sites	0.685	0.315	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.685	0.315	0.000
E04.1 Non-toxic single thyroid nodule	0.685	0.315	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.682	0.318	0.000
Chapter XX External causes of morbidity and mortality	0.682	0.318	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.681	0.319	0.000
M33 Dermatopolymyositis	0.681	0.319	0.000
M32 Systemic lupus erythematosus	0.681	0.319	0.000
C17 Malignant neoplasm of small intestine	0.678	0.322	0.000
C32.1 Supraglottis	0.676	0.323	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.675	0.325	0.000
E00 Congenital iodine-deficiency syndrome	0.675	0.325	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.675	0.325	0.000
M79.7 Fibromyalgia	0.674	0.326	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.671	0.329	0.000
C18.2 Ascending colon	0.670	0.330	0.000
M31.3 Wegener's granulomatosis	0.670	0.330	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.670	0.330	0.000
M54.37 Sciatica (Lumbosacral region)	0.670	0.330	0.000
M79.9 Soft tissue disorder, unspecified	0.669	0.331	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.669	0.331	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.667	0.333	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.667	0.333	0.000
C31 Malignant neoplasm of accessory sinuses	0.667	0.333	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.667	0.333	0.000
C37 Malignant neoplasm of thymus	0.667	0.333	0.000
C33 Malignant neoplasm of trachea	0.667	0.333	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.666	0.334	0.000
M35.8 Other specified systemic involvement of connective tissue	0.666	0.334	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.666	0.334	0.000
M35.5 Multifocal fibrosclerosis	0.666	0.334	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.666	0.334	0.000
M35.2 Behcet's disease	0.666	0.334	0.000
M77.1 Lateral epicondylitis	0.666	0.334	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.666	0.334	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.666	0.334	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.665	0.335	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.664	0.336	0.000
C23 Malignant neoplasm of gallbladder	0.663	0.337	0.000
M21 Other acquired deformities of limbs	0.663	0.337	0.000
C22.0 Liver cell carcinoma	0.663	0.337	0.000
S20 Superficial injury of thorax	0.663	0.337	0.000
C34.8 Overlapping lesion of bronchus and lung	0.663	0.337	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.662	0.338	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.661	0.339	0.000
S27 Injury of other and unspecified intrathoracic organs	0.660	0.340	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.658	0.341	0.000
D07.1 Vulva	0.657	0.343	0.000
Q43 Other congenital malformations of intestine	0.657	0.343	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.655	0.345	0.000
M07 Psoriatic and enteropathic arthropathies	0.655	0.345	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.653	0.347	0.000
M71 Other bursopathies	0.652	0.348	0.000
M79.2 Neuralgia and neuritis, unspecified	0.652	0.348	0.000
C16.8 Overlapping lesion of stomach	0.651	0.349	0.000
C16.6 Greater curvature of stomach, unspecified	0.651	0.349	0.000
C16.4 Pylorus	0.651	0.349	0.000
C16.3 Pyloric antrum	0.651	0.349	0.000
C16.2 Body of stomach	0.651	0.349	0.000
C16.1 Fundus of stomach	0.651	0.349	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.651	0.349	0.000
S51 Open wound of forearm	0.648	0.352	0.000
M31.6 Other giant cell arteritis	0.647	0.353	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.645	0.354	0.000
M06.38 Rheumatoid nodule (Other)	0.645	0.354	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.645	0.354	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.645	0.354	0.000
M06.33 Rheumatoid nodule (Forearm)	0.645	0.354	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.645	0.354	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.645	0.354	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.645	0.355	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.644	0.356	0.000
M79.3 Panniculitis, unspecified	0.644	0.356	0.000
M24.2 Disorder of ligament	0.644	0.356	0.000
M94 Other disorders of cartilage	0.642	0.358	0.000
C34.2 Middle lobe, bronchus or lung	0.641	0.359	0.000
S10-S19 Injuries to the neck	0.641	0.359	0.000
D06.9 Cervix, unspecified	0.641	0.359	0.000
C18.8 Overlapping lesion of colon	0.639	0.360	0.000
C71 Malignant neoplasm of brain	0.639	0.361	0.000
M66 Spontaneous rupture of synovium and tendon	0.638	0.362	0.000
S80-S89 Injuries to the knee and lower leg	0.638	0.362	0.000
F99-F99 Unspecified mental disorder	0.637	0.363	0.000
E06 Thyroiditis	0.637	0.363	0.000
T66-T78 Other and unspecified effects of external causes	0.636	0.364	0.000
M79.62 Pain in limb (Upper arm)	0.634	0.366	0.000
C34.0 Main bronchus	0.634	0.366	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.633	0.367	0.000
D07.4 Penis	0.633	0.367	0.000
M79.88 Other specified soft tissue disorders (Other)	0.632	0.368	0.000
E07 Other disorders of thyroid	0.632	0.368	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.631	0.369	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.631	0.369	0.000
C18.5 Splenic flexure	0.630	0.370	0.000
C18.1 Appendix	0.629	0.371	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.628	0.372	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.627	0.373	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.627	0.373	0.000
M24.6 Ankylosis of joint	0.626	0.374	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.626	0.374	0.000
C60-C63 Malignant neoplasms of male genital organs	0.625	0.375	0.000
F30-F39 Mood [affective] disorders	0.624	0.376	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.624	0.376	0.000
C21.2 Cloacogenic zone	0.624	0.376	0.000
M41.9 Scoliosis, unspecified	0.624	0.376	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.622	0.378	0.000
M42 Spinal osteochondrosis	0.621	0.379	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.621	0.379	0.000
M79.5 Residual foreign body in soft tissue	0.620	0.380	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.619	0.380	0.000
M72.2 Plantar fascial fibromatosis	0.619	0.381	0.000
F22 Persistent delusional disorders	0.619	0.381	0.000
Q00-Q07 Congenital malformations of the nervous system	0.619	0.381	0.000
M22.4 Chondromalacia patellae	0.619	0.381	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.619	0.381	0.000
Q35-Q37 Cleft lip and cleft palate	0.619	0.381	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.619	0.381	0.000
M35.7 Hypermobility syndrome	0.617	0.383	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.617	0.383	0.000
M12.5 Traumatic arthropathy	0.617	0.383	0.000
M12.4 Intermittent hydrarthrosis	0.617	0.383	0.000
M12.2 Villonodular synovitis (pigmented)	0.617	0.383	0.000
M12.1 Kaschin-Beck disease	0.617	0.383	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.617	0.383	0.000
M70.7 Other bursitis of hip	0.616	0.384	0.000
M43 Other deforming dorsopathies	0.616	0.384	0.000
D01.3 Anus and anal canal	0.615	0.385	0.000
M70.2 Olecranon bursitis	0.614	0.385	0.000
M54.36 Sciatica (Lumbar region)	0.614	0.386	0.000
M11.2 Other chondrocalcinosis	0.614	0.386	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.614	0.386	0.000
S40-S49 Injuries to the shoulder and upper arm	0.613	0.387	0.000
C18.9 Colon, unspecified	0.612	0.388	0.000
J40 Bronchitis, not specified as acute or chronic	0.612	0.388	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.612	0.388	0.000
E04.9 Non-toxic goitre, unspecified	0.612	0.388	0.000
C34.1 Upper lobe, bronchus or lung	0.611	0.389	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.610	0.390	0.000
D07.2 Vagina	0.608	0.392	0.000
W20-W49 Exposure to inanimate mechanical forces	0.607	0.393	0.000
J44 Other chronic obstructive pulmonary disease	0.607	0.393	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.606	0.394	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.606	0.394	0.000
T51 Toxic effect of alcohol	0.606	0.394	0.000
M77.0 Medial epicondylitis	0.605	0.395	0.000
M53 Other dorsopathies, not elsewhere classified	0.605	0.395	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.605	0.395	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.605	0.395	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.605	0.395	0.000
J20-J22 Other acute lower respiratory infections	0.604	0.396	0.000
J42 Unspecified chronic bronchitis	0.603	0.396	0.000
M24.0 Loose body in joint	0.603	0.397	0.000
Q80-Q89 Other congenital malformations	0.601	0.399	0.000
M20 Acquired deformities of fingers and toes	0.600	0.400	0.000
M80-M85 Disorders of bone density and structure	0.599	0.401	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.599	0.401	0.000
M77.5 Other enthesopathy of foot	0.599	0.401	0.000
M77.3 Calcaneal spur	0.599	0.401	0.000
M77.2 Periarthritis of wrist	0.599	0.401	0.000
F80-F89 Disorders of psychological development	0.599	0.401	0.000
M70.4 Prepatellar bursitis	0.598	0.402	0.000
M60 Myositis	0.597	0.403	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.597	0.403	0.000
M62 Other disorders of muscle	0.595	0.405	0.000
M77.9 Enthesopathy, unspecified	0.595	0.405	0.000
E50-E64 Other nutritional deficiencies	0.594	0.406	0.000
J00-J06 Acute upper respiratory infections	0.594	0.406	0.000
C32.8 Overlapping lesion of larynx	0.593	0.407	0.000
C32.3 Laryngeal cartilage	0.593	0.407	0.000
C32.2 Subglottis	0.593	0.407	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.592	0.408	0.000
M40.2 Other and unspecified kyphosis	0.590	0.410	0.000
M70.6 Trochanteric bursitis	0.590	0.410	0.000
J98 Other respiratory disorders	0.590	0.410	0.000
F22.0 Delusional disorder	0.588	0.412	0.000
M54.35 Sciatica (Thoracolumbar region)	0.587	0.413	0.000
M54.34 Sciatica-Thoracic	0.587	0.413	0.000
M54.33 Sciatica-Cervicothoracic	0.587	0.413	0.000
M54.32 Sciatica-Cervical	0.587	0.413	0.000
M54.31 Sciatica-Occipit-atl-axl	0.587	0.413	0.000
M54.30 Sciatica (Multiple sites in spine)	0.587	0.413	0.000
C22.1 Intrahepatic bile duct carcinoma	0.586	0.414	0.000
M54.8 Other dorsalgia	0.586	0.414	0.000
M54.0 Panniculitis affecting regions of neck and back	0.586	0.414	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.586	0.414	0.000
S51.0 Open wound of elbow	0.585	0.415	0.000
M31.9 Necrotising vasculopathy, unspecified	0.583	0.417	0.000
M31.8 Other specified necrotising vasculopathies	0.583	0.417	0.000
M31.7 Microscopic polyangiitis	0.583	0.417	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.583	0.417	0.000
M31.2 Lethal midline granuloma	0.583	0.417	0.000
M31.1 Thrombotic microangiopathy	0.583	0.417	0.000
M31.0 Hypersensitivity angiitis	0.583	0.417	0.000
S90-S99 Injuries to the ankle and foot	0.583	0.417	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.582	0.418	0.000
M54.1 Radiculopathy	0.581	0.419	0.000
W50-W64 Exposure to animate mechanical forces	0.581	0.419	0.000
S22.4 Multiple fractures of ribs	0.581	0.419	0.000
E40-E46 Malnutrition	0.580	0.420	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.579	0.421	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.578	0.421	0.000
E28 Ovarian dysfunction	0.576	0.424	0.000
M10.9 Gout, unspecified	0.576	0.424	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.576	0.424	0.000
T33-T35 Frostbite	0.574	0.426	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.574	0.426	0.000
T00-T07 Injuries involving multiple body regions	0.574	0.426	0.000
J96 Respiratory failure, not elsewhere classified	0.572	0.427	0.000
S86 Injury of muscle and tendon at lower leg level	0.572	0.428	0.000
M45-M49 Spondylopathies	0.572	0.428	0.000
E23 Hypofunction and other disorders of pituitary gland	0.571	0.429	0.000
E34 Other endocrine disorders	0.571	0.429	0.000
S81 Open wound of lower leg	0.571	0.429	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.571	0.429	0.000
S50 Superficial injury of forearm	0.571	0.429	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.570	0.430	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.570	0.430	0.000
M70.5 Other bursitis of knee	0.570	0.430	0.000
M70.3 Other bursitis of elbow	0.570	0.430	0.000
M70.1 Bursitis of hand	0.570	0.430	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.570	0.430	0.000
Q51 Congenital malformations of uterus and cervix	0.569	0.431	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.569	0.431	0.000
Q43.0 Meckel's diverticulum	0.568	0.432	0.000
M89 Other disorders of bone	0.567	0.432	0.000
C26.0 Intestinal tract, part unspecified	0.567	0.433	0.000
M99 Biomechanical lesions, not elsewhere classified	0.565	0.435	0.000
M92 Other juvenile osteochondrosis	0.563	0.437	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.563	0.437	0.000
Q63 Other congenital malformations of kidney	0.561	0.439	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.560	0.439	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.560	0.440	0.000
M61 Calcification and ossification of muscle	0.560	0.440	0.000
E04.8 Other specified non-toxic goitre	0.560	0.440	0.000
T51.0 Ethanol	0.559	0.441	0.000
Q61 Cystic kidney disease	0.559	0.441	0.000
C15.3 Upper third of oesophagus	0.559	0.441	0.000
S29 Other and unspecified injuries of thorax	0.559	0.441	0.000
Q54 Hypospadias	0.558	0.441	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.558	0.441	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.558	0.441	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.558	0.441	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.558	0.441	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.558	0.441	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.558	0.441	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.558	0.441	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.558	0.441	0.000
C15.9 Oesophagus, unspecified	0.559	0.441	0.000
C45 Mesothelioma	0.557	0.443	0.000
M54.4 Lumbago with sciatica	0.557	0.443	0.000
M24.9 Joint derangement, unspecified	0.556	0.444	0.000
M24.7 Protrusio acetabuli	0.556	0.444	0.000
M24.5 Contracture of joint	0.556	0.444	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.556	0.444	0.000
M11.9 Crystal arthropathy, unspecified	0.556	0.444	0.000
M11.8 Other specified crystal arthropathies	0.556	0.444	0.000
M11.1 Familial chondrocalcinosis	0.556	0.444	0.000
M11.0 Hydroxyapatite deposition disease	0.556	0.444	0.000
E29 Testicular dysfunction	0.555	0.444	0.000
M79.60 Pain in limb (Multiple sites)	0.555	0.445	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.555	0.445	0.000
D04 Carcinoma in situ of skin	0.555	0.445	0.000
M79.67 Pain in limb (Ankle and foot)	0.555	0.445	0.000
M90 Osteopathies in diseases classified elsewhere	0.554	0.446	0.000
D02.4 Respiratory system, unspecified	0.554	0.446	0.000
D02.3 Other parts of respiratory system	0.554	0.446	0.000
D02.2 Bronchus and lung	0.554	0.446	0.000
D02.1 Trachea	0.554	0.446	0.000
S41 Open wound of shoulder and upper arm	0.553	0.447	0.000
F99 Mental disorder, not otherwise specified	0.553	0.447	0.000
C32.9 Larynx, unspecified	0.552	0.448	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.552	0.448	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.552	0.448	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.552	0.448	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.552	0.448	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.552	0.448	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.552	0.448	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.552	0.448	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.552	0.448	0.000
C22.7 Other specified carcinomas of liver	0.551	0.449	0.000
C22.4 Other sarcomas of liver	0.551	0.449	0.000
C22.3 Angiosarcoma of liver	0.551	0.449	0.000
C22.2 Hepatoblastoma	0.551	0.449	0.000
C05 Malignant neoplasm of palate	0.550	0.450	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.549	0.451	0.000
M35.0 Sicca syndrome [Sjogren]	0.549	0.451	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.548	0.452	0.000
S22.40 Multiple fractures of ribs (closed)	0.548	0.452	0.000
M65 Synovitis and tenosynovitis	0.548	0.452	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.547	0.453	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.547	0.453	0.000
T79.6 Traumatic ischaemia of muscle	0.547	0.453	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.546	0.454	0.000
S26 Injury of heart	0.546	0.454	0.000
S25 Injury of blood vessels of thorax	0.546	0.454	0.000
S24 Injury of nerves and spinal cord at thorax level	0.546	0.454	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.546	0.454	0.000
S21 Open wound of thorax	0.546	0.454	0.000
M93 Other osteochondropathies	0.546	0.454	0.000
M12.38 Palindromic rheumatism (Other)	0.545	0.455	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.545	0.455	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.545	0.455	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.545	0.455	0.000
M12.34 Palindromic rheumatism (Hand)	0.545	0.455	0.000
M12.33 Palindromic rheumatism (Forearm)	0.545	0.455	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.545	0.455	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.545	0.455	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.545	0.455	0.000
M13.98 Arthritis, unspecified (Other)	0.544	0.456	0.000
S27.0 Traumatic pneumothorax	0.543	0.457	0.000
S54 Injury of nerves at forearm level	0.543	0.457	0.000
D09.0 Bladder	0.543	0.457	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.543	0.457	0.000
E04.0 Non-toxic diffuse goitre	0.543	0.457	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.541	0.458	0.000
F70-F79 Mental retardation	0.541	0.458	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.541	0.459	0.000
C70 Malignant neoplasm of meninges	0.541	0.459	0.000
M88 Paget's disease of bone [osteitis deformans]	0.540	0.459	0.000
M10.4 Other secondary gout	0.540	0.460	0.000
M10.3 Gout due to impairment of renal function	0.540	0.460	0.000
M10.2 Drug-induced gout	0.540	0.460	0.000
M10.1 Lead-induced gout	0.540	0.460	0.000
M10.0 Idiopathic gout	0.540	0.460	0.000
M66.2 Spontaneous rupture of extensor tendons	0.539	0.460	0.000
F31 Bipolar affective disorder	0.539	0.461	0.000
D07.6 Other and unspecified male genital organs	0.539	0.461	0.000
D07.3 Other and unspecified female genital organs	0.539	0.461	0.000
D07.0 Endometrium	0.539	0.461	0.000
C09 Malignant neoplasm of tonsil	0.539	0.461	0.000
M54.6 Pain in thoracic spine	0.538	0.461	0.000
Q45 Other congenital malformations of digestive system	0.538	0.462	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.538	0.462	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.538	0.462	0.000
Q40 Other congenital malformations of upper alimentary tract	0.538	0.462	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations