TreeWAS – Variant ID: rs17104944

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	0.985	0.015
Chapter V Mental and behavioural disorders	0.985	0.015
F10 Mental and behavioural disorders due to use of alcohol	0.984	0.016
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.984	0.016
Chapter XX External causes of morbidity and mortality	0.976	0.024
S40-S49 Injuries to the shoulder and upper arm	0.974	0.026
S00-S09 Injuries to the head	0.971	0.029
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.967	0.033
F10.0 Acute intoxication	0.964	0.036
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.963	0.037
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.962	0.038
Chapter VI Diseases of the nervous system	0.960	0.040
S20-S29 Injuries to the thorax	0.959	0.041
F00-F09 Organic, including symptomatic, mental disorders	0.951	0.049
T20-T25 Burns and corrosions of external body surface, specified by site	0.948	0.052
G90-G99 Other disorders of the nervous system	0.946	0.054
Chapter VII Diseases of the eye and adnexa	0.940	0.060
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.937	0.063
Y40 Systemic antibiotics	0.936	0.064
Q00-Q07 Congenital malformations of the nervous system	0.935	0.065
F10.1 Harmful use	0.935	0.065
S60-S69 Injuries to the wrist and hand	0.922	0.078
G91 Hydrocephalus	0.922	0.078
S40 Superficial injury of shoulder and upper arm	0.919	0.081
S01 Open wound of head	0.916	0.084
T36-T50 Poisoning by drugs, medicaments and biological substances	0.915	0.085
S32 Fracture of lumbar spine and pelvis	0.913	0.087
F05 Delirium, not induced by alcohol and other psychoactive substances	0.912	0.088
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.912	0.088
Q07 Other congenital malformations of nervous system	0.905	0.095
G91.9 Hydrocephalus, unspecified	0.904	0.096
G40-G47 Episodic and paroxysmal disorders	0.896	0.104
G40 Epilepsy	0.893	0.107
G30-G32 Other degenerative diseases of the nervous system	0.889	0.111
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.883	0.117
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.883	0.117
Q07.0 Arnold-Chiari syndrome	0.883	0.117
F05.9 Delirium, unspecified	0.882	0.118
S09 Other and unspecified injuries of head	0.881	0.119
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.878	0.122
S22 Fracture of rib(s), sternum and thoracic spine	0.877	0.123
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.877	0.123
G40.9 Epilepsy, unspecified	0.877	0.123
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.875	0.125
Y52 Agents primarily affecting the cardiovascular system	0.875	0.125
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.872	0.128
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.870	0.130
S27 Injury of other and unspecified intrathoracic organs	0.862	0.138
S70-S79 Injuries to the hip and thigh	0.862	0.138
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.860	0.140
F10.5 Psychotic disorder	0.858	0.142
S01.1 Open wound of eyelid and periocular area	0.857	0.143
S10-S19 Injuries to the neck	0.856	0.144
Y40.0 Penicillins	0.856	0.144
F10.3 Withdrawal state	0.846	0.154
Y40.8 Other systemic antibiotics	0.843	0.157
T51 Toxic effect of alcohol	0.836	0.164
H43-H45 Disorders of vitreous body and globe	0.832	0.168
G93 Other disorders of brain	0.830	0.170
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.829	0.171
H18 Other disorders of cornea	0.828	0.172
S00 Superficial injury of head	0.828	0.172
S62 Fracture at wrist and hand level	0.828	0.172
X60-X84 Intentional self-harm	0.826	0.174
S30 Superficial injury of abdomen, lower back and pelvis	0.823	0.177
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.821	0.179
Q20-Q28 Congenital malformations of the circulatory system	0.820	0.180
S32.7 Multiple fractures of lumbar spine and pelvis	0.819	0.181
T43.2 Other and unspecified antidepressants	0.817	0.183
F10.4 Withdrawal state with delirium	0.815	0.184
S01.0 Open wound of scalp	0.813	0.187
R25 Abnormal involuntary movements	0.811	0.189
H53-H54 Visual disturbances and blindness	0.808	0.192
R45 Symptoms and signs involving emotional state	0.807	0.193
R47-R49 Symptoms and signs involving speech and voice	0.800	0.200
G30 Alzheimer's disease	0.799	0.201
W20-W49 Exposure to inanimate mechanical forces	0.795	0.205
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.793	0.207
R41 Other symptoms and signs involving cognitive functions and awareness	0.793	0.207
Y40.1 Cefalosporins and other -lactam antibiotics	0.792	0.208
H20 Iridocyclitis	0.792	0.208
S09.9 Unspecified injury of head	0.790	0.210
S69 Other and unspecified injuries of wrist and hand	0.790	0.210
W00-W19 Falls	0.790	0.210
S42 Fracture of shoulder and upper arm	0.790	0.210
F01 Vascular dementia	0.787	0.213
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.787	0.213
S66 Injury of muscle and tendon at wrist and hand level	0.786	0.214
S01.5 Open wound of lip and oral cavity	0.785	0.215
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.784	0.216
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.781	0.219
S46 Injury of muscle and tendon at shoulder and upper arm level	0.778	0.222
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.773	0.226
T21 Burn and corrosion of trunk	0.772	0.228
Y53 Agents primarily affecting the gastro-intestinal system	0.772	0.228
S22.0 Fracture of thoracic vertebra	0.771	0.229
T15-T19 Effects of foreign body entering through natural orifice	0.770	0.230
T23 Burn and corrosion of wrist and hand	0.769	0.231
F00 Dementia in Alzheimer's disease	0.765	0.235
S41 Open wound of shoulder and upper arm	0.763	0.237
Y52.4 Angiotensin-converting-enzyme inhibitors	0.762	0.238
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.761	0.239
T51.0 Ethanol	0.760	0.240
F10.2 Dependence syndrome	0.759	0.241
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.758	0.242
S32.1 Fracture of sacrum	0.758	0.242
H55-H59 Other disorders of eye and adnexa	0.757	0.243
G93.6 Cerebral oedema	0.757	0.243
S90-S99 Injuries to the ankle and foot	0.756	0.244
H21 Other disorders of iris and ciliary body	0.755	0.245
Y47 Sedatives, hypnotics and antianxiety drugs	0.752	0.248
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.751	0.249
V40-V49 Car occupant injured in transport accident	0.751	0.249
S21 Open wound of thorax	0.751	0.249
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.751	0.249
Y49 Psychotropic drugs, not elsewhere classified	0.751	0.249
S50-S59 Injuries to the elbow and forearm	0.750	0.250
H46-H48 Disorders of optic nerve and visual pathways	0.749	0.251
X50-X57 Overexertion, travel and privation	0.748	0.252
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.747	0.253
S32.5 Fracture of pubis	0.747	0.253
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.746	0.254
Q05 Spina bifida	0.744	0.256
T63 Toxic effect of contact with venomous animals	0.744	0.256
T20 Burn and corrosion of head and neck	0.743	0.257
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.741	0.259
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.739	0.261
H30-H36 Disorders of choroid and retina	0.739	0.261
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.738	0.261
G96 Other disorders of central nervous system	0.736	0.264
G30.9 Alzheimer's disease, unspecified	0.735	0.265
T56 Toxic effect of metals	0.732	0.268
X20-X29 Contact with venomous animals and plants	0.729	0.271
T58 Toxic effect of carbon monoxide	0.729	0.271
S22.5 Flail chest	0.729	0.271
R47 Speech disturbances, not elsewhere classified	0.728	0.272
T00-T07 Injuries involving multiple body regions	0.728	0.272
Q38-Q45 Other congenital malformations of the digestive system	0.727	0.273
R44 Other symptoms and signs involving general sensations and perceptions	0.727	0.273
R87 Abnormal findings in specimens from female genital organs	0.727	0.273
H54 Blindness and low vision	0.727	0.273
Y41 Other systemic anti-infectives and antiparasitics	0.727	0.273
V80-V89 Other land transport accidents	0.727	0.273
Q50-Q56 Congenital malformations of genital organs	0.726	0.273
S80-S89 Injuries to the knee and lower leg	0.726	0.274
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.726	0.274
F99-F99 Unspecified mental disorder	0.724	0.276
S05 Injury of eye and orbit	0.723	0.277
S68 Traumatic amputation of wrist and hand	0.722	0.278
Y46 Antiepileptics and anti-Parkinsonism drugs	0.721	0.279
R25.2 Cramp and spasm	0.721	0.279
X58-X59 Accidental exposure to other and unspecified factors	0.720	0.279
S62.3 Fracture of other metacarpal bone	0.719	0.281
H44 Disorders of globe	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
G94 Other disorders of brain in diseases classified elsewhere	0.716	0.283
S36 Injury of intra-abdominal organs	0.716	0.284
G90 Disorders of autonomic nervous system	0.716	0.284
T79-T79 Certain early complications of trauma	0.715	0.285
W22 Striking against or struck by other objects	0.712	0.288
R45.8 Other symptoms and signs involving emotional state	0.712	0.288
S10 Superficial injury of neck	0.711	0.289
R47.0 Dysphasia and aphasia	0.710	0.290
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.710	0.290
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.291
R25.1 Tremor, unspecified	0.708	0.292
F80-F89 Disorders of psychological development	0.707	0.292
S27.2 Traumatic heamopneumothorax	0.707	0.293
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.293
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294
F70-F79 Mental retardation	0.706	0.294
H20.9 Iridocyclitis, unspecified	0.706	0.294
F10.8 Other mental and behavioural disorders	0.706	0.294
F10.7 Residual and late-onset psychotic disorder	0.706	0.294
F10.6 Amnesic syndrome	0.706	0.294
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.706	0.294
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.705	0.295
F18 Mental and behavioural disorders due to use of volatile solvents	0.705	0.295
F16 Mental and behavioural disorders due to use of hallucinogens	0.705	0.295
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.705	0.295
F14 Mental and behavioural disorders due to use of cocaine	0.705	0.295
F11 Mental and behavioural disorders due to use of opioids	0.705	0.295
T98 Sequelae of other and unspecified effects of external causes	0.705	0.295
S09.8 Other specified injuries of head	0.705	0.295
S22.2 Fracture of sternum	0.703	0.297
T43.3 Phenothiazine antipsychotics and neuroleptics	0.703	0.297
X10-X19 Contact with heat and hot substances	0.702	0.298
Y00-Y09 Assault	0.701	0.299
H17 Corneal scars and opacities	0.701	0.299
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.701	0.299
T95 Sequelae of burns, corrosions and frostbite	0.700	0.300
T46 Poisoning by agents primarily affecting the cardiovascular system	0.699	0.300
Y35-Y36 Legal intervention and operations of war	0.699	0.300
Y10-Y34 Event of undetermined intent	0.699	0.300
X85-X99 Assault	0.699	0.300
X30-X39 Exposure to forces of nature	0.699	0.300
X00-X09 Exposure to smoke, fire and flames	0.699	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.699	0.300
W75-W84 Other accidental threats to breathing	0.699	0.300
W65-W74 Accidental drowning and submersion	0.699	0.300
V98-V99 Other and unspecified transport accidents	0.699	0.300
V95-V97 Air and space transport accidents	0.699	0.300
V90-V94 Water transport accidents	0.699	0.300
V70-V79 Bus occupant injured in transport accident	0.699	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.699	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.699	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.699	0.300
V01-V09 Pedestrian injured in transport accident	0.699	0.300
S67 Crushing injury of wrist and hand	0.699	0.301
S72 Fracture of femur	0.699	0.301
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.699	0.301
W50-W64 Exposure to animate mechanical forces	0.699	0.301
S48 Traumatic amputation of shoulder and upper arm	0.698	0.302
S45 Injury of blood vessels at shoulder and upper arm level	0.698	0.302
S44 Injury of nerves at shoulder and upper arm level	0.698	0.302
S47 Crushing injury of shoulder and upper arm	0.698	0.302
T43.0 Tricyclic and tetracyclic antidepressants	0.698	0.302
H40-H42 Glaucoma	0.698	0.302
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.698	0.302
S80 Superficial injury of lower leg	0.697	0.303
G00-G09 Inflammatory diseases of the central nervous system	0.696	0.304
F10.9 Unspecified mental and behavioural disorder	0.696	0.304
S08 Traumatic amputation of part of head	0.696	0.304
S07 Crushing injury of head	0.696	0.304
S04 Injury of cranial nerves	0.696	0.304
S03 Dislocation, sprain and strain of joints and ligaments of head	0.696	0.304
S62.5 Fracture of thumb	0.695	0.305
S22.00 Fracture of thoracic vertebra (closed)	0.695	0.305
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.693	0.307
Q35-Q37 Cleft lip and cleft palate	0.693	0.307
Q30-Q34 Congenital malformations of the respiratory system	0.693	0.307
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.692	0.307
S19 Other and unspecified injuries of neck	0.692	0.308
S70 Superficial injury of hip and thigh	0.691	0.308
T66-T78 Other and unspecified effects of external causes	0.691	0.309
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.691	0.309
S27.3 Other injuries of lung	0.691	0.309
X40-X49 Accidental poisoning by and exposure to noxious substances	0.691	0.309
Y59 Other and unspecified vaccines and biological substances	0.690	0.310
Y58 Bacterial vaccines	0.690	0.310
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.690	0.310
Y50 Central nervous system stimulants, not elsewhere classified	0.690	0.310
Y48 Anaesthetics and therapeutic gases	0.690	0.310
S32.3 Fracture of ilium	0.690	0.310
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.689	0.310
S37 Injury of urinary and pelvic organs	0.689	0.310
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.689	0.310
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.689	0.310
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.689	0.310
S31 Open wound of abdomen, lower back and pelvis	0.689	0.310
T91 Sequelae of injuries of neck and trunk	0.689	0.311
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.689	0.311
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.688	0.312
S26 Injury of heart	0.688	0.312
S25 Injury of blood vessels of thorax	0.688	0.312
S24 Injury of nerves and spinal cord at thorax level	0.688	0.312
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.688	0.312
S27.8 Injury of other specified intrathoracic organs	0.687	0.313
Y60-Y69 Misadventures to patients during surgical and medical care	0.686	0.313
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.686	0.314
H18.8 Other specified disorders of cornea	0.685	0.315
F02 Dementia in other diseases classified elsewhere	0.685	0.315
S01.3 Open wound of ear	0.684	0.316
R41.0 Disorientation, unspecified	0.683	0.317
F05.8 Other delirium	0.682	0.318
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.682	0.318
F09 Unspecified organic or symptomatic mental disorder	0.682	0.318
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.682	0.318
T25 Burn and corrosion of ankle and foot	0.680	0.320
R27 Other lack of coordination	0.680	0.320
S00.5 Superficial injury of lip and oral cavity	0.679	0.321
Y40.3 Macrolides	0.679	0.321
S40.0 Contusion of shoulder and upper arm	0.679	0.321
F12 Mental and behavioural disorders due to use of cannabinoids	0.678	0.322
G98 Other disorders of nervous system, not elsewhere classified	0.678	0.322
G92 Toxic encephalopathy	0.678	0.322
R45.5 Hostility	0.678	0.322
R87.6 Abnormal cytological findings	0.677	0.323
S00.9 Superficial injury of head, part unspecified	0.676	0.324
S60 Superficial injury of wrist and hand	0.675	0.325
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.675	0.325
T36 Poisoning by systemic antibiotics	0.673	0.327
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.672	0.328
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.672	0.328
T65 Toxic effect of other and unspecified substances	0.672	0.328
T62 Toxic effect of other noxious substances eaten as food	0.672	0.328
T61 Toxic effect of noxious substances eaten as seafood	0.672	0.328
T60 Toxic effect of pesticides	0.672	0.328
T59 Toxic effect of other gases, fumes and vapours	0.672	0.328
T57 Toxic effect of other inorganic substances	0.672	0.328
T54 Toxic effect of corrosive substances	0.672	0.328
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.672	0.328
T52 Toxic effect of organic solvents	0.672	0.328
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.672	0.328
T55 Toxic effect of soaps and detergents	0.672	0.328
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.672	0.328
Y40.7 Antifungal antibiotics, systemically used	0.671	0.329
Y40.6 Rifamycins	0.671	0.329
Y40.5 Aminoglycosides	0.671	0.329
Y40.4 Tetracyclines	0.671	0.329
Y40.2 Chloramphenicol group	0.671	0.329
G40.7 Petit mal, unspecified, without grand mal seizures	0.671	0.329
Q06 Other congenital malformations of spinal cord	0.671	0.329
Q04 Other congenital malformations of brain	0.671	0.329
Q03 Congenital hydrocephalus	0.671	0.329
Q01 Encephalocele	0.671	0.329
Q00 Anencephaly and similar malformations	0.671	0.329
Q02 Microcephaly	0.671	0.329
H43 Disorders of vitreous body	0.671	0.329
F01.9 Vascular dementia, unspecified	0.670	0.330
Q27 Other congenital malformations of peripheral vascular system	0.669	0.331
H18.9 Disorder of cornea, unspecified	0.668	0.331
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.667	0.332
T90 Sequelae of injuries of head	0.667	0.333
G91.1 Obstructive hydrocephalus	0.667	0.333
S00.4 Superficial injury of ear	0.667	0.333
S20 Superficial injury of thorax	0.663	0.336
V20-V29 Motorcycle rider injured in transport accident	0.663	0.337
G93.1 Anoxic brain damage, not elsewhere classified	0.662	0.338
S32.0 Fracture of lumbar vertebra	0.661	0.339
Y57 Other and unspecified drugs and medicaments	0.661	0.339
S65 Injury of blood vessels at wrist and hand level	0.661	0.339
G91.8 Other hydrocephalus	0.661	0.339
G91.3 Posttraumatic hydrocephalus, unspecified	0.661	0.339
G91.2 Normal-pressure hydrocephalus	0.661	0.339
G91.0 Communicating hydrocephalus	0.661	0.339
G70-G73 Diseases of myoneural junction and muscle	0.660	0.339
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.660	0.340
S40.8 Other superficial injuries of shoulder and upper arm	0.659	0.341
S40.7 Multiple superficial injuries of shoulder and upper arm	0.659	0.341
R44.3 Hallucinations, unspecified	0.659	0.341
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.658	0.342
S22.3 Fracture of rib	0.657	0.342
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.656	0.344
S71 Open wound of hip and thigh	0.656	0.344
S22.1 Multiple fractures of thoracic spine	0.656	0.344
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.656	0.344
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.656	0.344
T41 Poisoning by anaesthetics and therapeutic gases	0.656	0.344
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.656	0.344
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.656	0.344
Y52.3 Coronary vasodilators, not elsewhere classified	0.656	0.344
G97.8 Other postprocedural disorders of nervous system	0.655	0.345
S32.2 Fracture of coccyx	0.655	0.345
F05.1 Delirium superimposed on dementia	0.654	0.346
F05.0 Delirium not superimposed on dementia, so described	0.654	0.346
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.654	0.346
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.654	0.346
H15 Disorders of sclera	0.654	0.346
S80.9 Superficial injury of lower leg, unspecified	0.654	0.346
W22.9 Unspecified place	0.653	0.347
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.651	0.348
S01.7 Multiple open wounds of head	0.651	0.349
Chapter XXII Codes for special purposes	0.651	0.349
G93.8 Other specified disorders of brain	0.650	0.350
X78 Intentional self-harm by sharp object	0.650	0.350
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.650	0.350
H18.4 Corneal degeneration	0.649	0.351
H34 Retinal vascular occlusions	0.649	0.351
H47 Other disorders of optic [2nd] nerve and visual pathways	0.649	0.351
Q07.9 Congenital malformation of nervous system, unspecified	0.649	0.351
Q07.8 Other specified congenital malformations of nervous system	0.649	0.351
H54.7 Unspecified visual loss	0.648	0.352
R43 Disturbances of smell and taste	0.647	0.353
S32.10 Fracture of sacrum (closed)	0.647	0.353
R41.3 Other amnesia	0.647	0.353
G93.9 Disorder of brain, unspecified	0.646	0.354
S69.9 Unspecified injury of wrist and hand	0.646	0.354
T21.0 Burn of unspecified degree of trunk	0.646	0.354
S01.4 Open wound of cheek and temporomandibular area	0.646	0.354
H21.5 Other adhesions and disruptions of iris and ciliary body	0.645	0.355
H16 Keratitis	0.644	0.356
S69.8 Other specified injuries of wrist and hand	0.644	0.356
Q80-Q89 Other congenital malformations	0.642	0.357
W08 Fall involving other furniture	0.642	0.358
G46 Vascular syndromes of brain in cerebrovascular diseases	0.642	0.358
Chapter VIII Diseases of the ear and mastoid process	0.641	0.359
G40.5 Special epileptic syndromes	0.640	0.359
G40.4 Other generalised epilepsy and epileptic syndromes	0.640	0.359
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.640	0.359
S62.30 Fracture of other metacarpal bone (closed)	0.640	0.359
T23.2 Burn of second degree of wrist and hand	0.640	0.360
H18.5 Hereditary corneal dystrophies	0.639	0.361
S29 Other and unspecified injuries of thorax	0.639	0.361
R25.3 Fasciculation	0.638	0.362
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.638	0.362
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.638	0.362
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.637	0.363
Y51 Drugs primarily affecting the autonomic nervous system	0.637	0.363
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.636	0.364
Y53.4 Other laxatives	0.636	0.364
F13.2 Dependence syndrome	0.636	0.364
S49 Other and unspecified injuries of shoulder and upper arm	0.635	0.365
S27.0 Traumatic pneumothorax	0.634	0.366
S06 Intracranial injury	0.634	0.366
S00.3 Superficial injury of nose	0.634	0.366
R95-R99 Ill-defined and unknown causes of mortality	0.633	0.367
S42.1 Fracture of scapula	0.633	0.367
Y52.1 Calcium-channel blockers	0.633	0.367
F00.9 Dementia in Alzheimer's disease, unspecified	0.632	0.368
S27.1 Traumatic haemothorax	0.632	0.368
Y44 Agents primarily affecting blood constituents	0.632	0.368
S09.7 Multiple injuries of head	0.632	0.368
S09.2 Traumatic rupture of ear drum	0.632	0.368
S09.1 Injury of muscle and tendon of head	0.632	0.368
S09.0 Injury of blood vessels of head, not elsewhere classified	0.632	0.368
T92 Sequelae of injuries of upper limb	0.629	0.371
W14 Fall from tree	0.629	0.371
S22.9 Fracture of bony thorax, part unspecified	0.629	0.371
S22.8 Fracture of other parts of bony thorax	0.629	0.371
R29.4 Clicking hip	0.629	0.371
R29.3 Abnormal posture	0.629	0.371
R29.2 Abnormal reflex	0.629	0.371
R29.1 Meningismus	0.629	0.371
R29.0 Tetany	0.629	0.371
R45.4 Irritability and anger	0.629	0.371
S32.50 Fracture of pubis (closed)	0.628	0.372
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.628	0.372
S14 Injury of nerves and spinal cord at neck level	0.627	0.373
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.627	0.373
Y52.8 Antivaricose drugs, including sclerosing agents	0.627	0.373
Y52.7 Peripheral vasodilators	0.627	0.373
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.627	0.373
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.627	0.373
S46.0 Injury of tendon of the rotator cuff of shoulder	0.627	0.373
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.627	0.373
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.626	0.374
Q66 Congenital deformities of feet	0.626	0.374
T43.9 Psychotropic drug, unspecified	0.625	0.375
T43.8 Other psychotropic drugs, not elsewhere classified	0.625	0.375
T43.6 Psychostimulants with abuse potential	0.625	0.375
T43.4 Butyrophenone and thioxanthene neuroleptics	0.625	0.375
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.625	0.375
W13 Fall from, out of or through building or structure	0.624	0.376
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.624	0.376
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.624	0.376
S43.5 Sprain and strain of acromioclavicular joint	0.624	0.376
R41.1 Anterograde amnesia	0.623	0.377
S32.4 Fracture of acetabulum	0.623	0.377
S42.0 Fracture of clavicle	0.623	0.377
S22.50 Flail chest (closed)	0.622	0.378
R45.1 Restlessness and agitation	0.620	0.380
H44.2 Degenerative myopia	0.619	0.381
Q23 Congenital malformations of aortic and mitral valves	0.619	0.381
S01.2 Open wound of nose	0.619	0.381
S27.9 Injury of unspecified intrathoracic organ	0.618	0.382
S27.7 Multiple injuries of intrathoracic organs	0.618	0.382
S27.6 Injury of pleura	0.618	0.382
S27.5 Injury of thoracic trachea	0.618	0.382
S27.4 Injury of bronchus	0.618	0.382
S78 Traumatic amputation of hip and thigh	0.618	0.382
S77 Crushing injury of hip and thigh	0.618	0.382
S76 Injury of muscle and tendon at hip and thigh level	0.618	0.382
S75 Injury of blood vessels at hip and thigh level	0.618	0.382
S74 Injury of nerves at hip and thigh level	0.618	0.382
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.618	0.382
Q21 Congenital malformations of cardiac septa	0.618	0.382
G31.9 Degenerative disease of nervous system, unspecified	0.617	0.383
S12 Fracture of neck	0.617	0.383
R49 Voice disturbances	0.616	0.384
Q24 Other congenital malformations of heart	0.614	0.385
G97.1 Other reaction to spinal and lumbar puncture	0.614	0.386
G93.2 Benign intracranial hypertension	0.614	0.386
S17 Crushing injury of neck	0.614	0.386
S15 Injury of blood vessels at neck level	0.614	0.386
S11 Open wound of neck	0.614	0.386
S18 Traumatic amputation at neck level	0.614	0.386
S16 Injury of muscle and tendon at neck level	0.614	0.386
H54.4 Blindness, one eye	0.613	0.387
S62.8 Fracture of other and unspecified parts of wrist and hand	0.612	0.388
S41.1 Open wound of upper arm	0.612	0.388
W20 Struck by thrown, projected or falling object	0.611	0.389
S79 Other and unspecified injuries of hip and thigh	0.609	0.391
T51.9 Alcohol, unspecified	0.609	0.391
S00.7 Multiple superficial injuries of head	0.608	0.392
Q05.9 Spina bifida, unspecified	0.607	0.392
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.607	0.392
W17 Other fall from one level to another	0.607	0.393
Y42.0 Glucocorticoids and synthetic analogs	0.607	0.393
Y91 Evidence of alcohol involvement determined by level of intoxication	0.607	0.393
S10.9 Superficial injury of neck, part unspecified	0.607	0.393
R26 Abnormalities of gait and mobility	0.606	0.394
R46 Symptoms and signs involving appearance and behaviour	0.606	0.394
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.606	0.394
G41 Status epilepticus	0.606	0.394
Q78 Other osteochondrodysplasias	0.606	0.394
Y40.9 Systemic antibiotic, unspecified	0.606	0.394
W05 Fall involving wheelchair	0.605	0.395
T63.4 Venom of other arthropods	0.605	0.395
W06 Fall involving bed	0.604	0.396
G80-G83 Cerebral palsy and other paralytic syndromes	0.604	0.396
S50 Superficial injury of forearm	0.603	0.397
F30-F39 Mood [affective] disorders	0.603	0.397
Q60-Q64 Congenital malformations of the urinary system	0.603	0.397
S72.3 Fracture of shaft of femur	0.602	0.398
S21.1 Open wound of front wall of thorax	0.602	0.398
Y47.1 Benzodiazepines	0.602	0.398
T94 Sequelae of injuries involving multiple and unspecified body regions	0.600	0.400

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations