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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17211510
log Bayes Factor = 186.894
Chromosome 6   position 32,602,430  (GRCh37) Explore rs17211510 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
D51 Vitamin B12 deficiency anaemia
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.000 1.000
Chapter VI Diseases of the nervous system
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.000 1.000
D06 Carcinoma in situ of cervix uteri
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E27 Other disorders of adrenal gland
0.000 0.001 0.999
D06.9 Cervix, unspecified
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
D07.1 Vulva
0.000 0.001 0.999
E27.1 Primary adrenocortical insufficiency
0.000 0.001 0.999
D64.9 Anaemia, unspecified
0.000 0.001 0.999
D64 Other anaemias
0.000 0.002 0.998
D60-D64 Aplastic and other anaemias
0.000 0.002 0.998
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.003 0.997
K50-K52 Noninfective enteritis and colitis
0.997 0.003 0.000
E11.9 Without complications
0.000 0.003 0.997
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.003 0.997
K50 Crohn's disease [regional enteritis]
0.997 0.003 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
K50.1 Crohn's disease of large intestine
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.005 0.995
E11.3 With ophthalmic complications
0.000 0.006 0.994
E16 Other disorders of pancreatic internal secretion
0.000 0.006 0.994
C80 Malignant neoplasm without specification of site
0.000 0.009 0.991
C15-C26 Malignant neoplasms of digestive organs
0.000 0.009 0.991
C21 Malignant neoplasm of anus and anal canal
0.000 0.010 0.990
E10.1 With ketoacidosis
0.000 0.010 0.990
L90 Atrophic disorders of skin
0.000 0.010 0.990
E16.2 Hypoglycaemia, unspecified
0.000 0.010 0.990
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.013 0.987
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.014 0.986
K51.4 Pseudopolyposis of colon
0.985 0.015 0.000
E50-E64 Other nutritional deficiencies
0.000 0.015 0.985
E14 Unspecified diabetes mellitus
0.000 0.015 0.985
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.016 0.984
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.018 0.982
E53 Deficiency of other B group vitamins
0.000 0.018 0.982
D50 Iron deficiency anaemia
0.000 0.018 0.982
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.019 0.981
E53.8 Deficiency of other specified B group vitamins
0.000 0.021 0.979
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.021 0.979
D50.9 Iron deficiency anaemia, unspecified
0.000 0.022 0.978
L90.0 Lichen sclerosus et atrophicus
0.000 0.022 0.978
C21.1 Anal canal
0.000 0.024 0.976
C21.0 Anus, unspecified
0.000 0.027 0.973
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.042 0.958
K90 Intestinal malabsorption
0.000 0.044 0.956
G00 Bacterial meningitis, not elsewhere classified
0.000 0.047 0.953
G81 Hemiplegia
0.000 0.056 0.944
E27.2 Addisonian crisis
0.000 0.057 0.943
L91 Hypertrophic disorders of skin
0.000 0.059 0.941
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.066 0.934
E14.3 With ophthalmic complications
0.000 0.068 0.932
E21.0 Primary hyperparathyroidism
0.000 0.074 0.926
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.075 0.925
L92.0 Granuloma annulare
0.000 0.080 0.920
G81.9 Hemiplegia, unspecified
0.000 0.083 0.917
G37 Other demyelinating diseases of central nervous system
0.000 0.084 0.916
L91.8 Other hypertrophic disorders of skin
0.000 0.093 0.907
E10.4 With neurological complications
0.000 0.094 0.906
C20 Malignant neoplasm of rectum
0.000 0.095 0.905
G83 Other paralytic syndromes
0.000 0.096 0.904
L50-L54 Urticaria and erythema
0.000 0.105 0.895
E10.6 With other specified complications
0.000 0.108 0.892
G00.1 Pneumococcal meningitis
0.000 0.111 0.889
E14.9 Without complications
0.000 0.112 0.888
E10.5 With peripheral circulatory complications
0.000 0.120 0.880
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.124 0.876
L89 Decubitus ulcer
0.000 0.124 0.876
E11.1 With ketoacidosis
0.000 0.127 0.873
D07.4 Penis
0.000 0.127 0.873
L50 Urticaria
0.000 0.127 0.873
L90.5 Scar conditions and fibrosis of skin
0.000 0.128 0.872
G00.9 Bacterial meningitis, unspecified
0.000 0.138 0.862
K50.9 Crohn's disease, unspecified
0.862 0.138 0.000
L10-L14 Bullous disorders
0.000 0.139 0.861
E20 Hypoparathyroidism
0.000 0.140 0.860
K51.5 Mucosal proctocolitis
0.856 0.144 0.000
C22.1 Intrahepatic bile duct carcinoma
0.000 0.146 0.854
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.146 0.854
Chapter XXII Codes for special purposes
0.000 0.151 0.849
K50.8 Other Crohn's disease
0.848 0.152 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.152 0.848
K51.2 Ulcerative (chronic) proctitis
0.846 0.154 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.156 0.844
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.157 0.843
E10.0 With coma
0.000 0.162 0.838
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.162 0.838
C34 Malignant neoplasm of bronchus and lung
0.000 0.165 0.835
J45 Asthma
0.000 0.168 0.832
E16.1 Other hypoglycaemia
0.000 0.169 0.831
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.173 0.827
C44 Other malignant neoplasms of skin
0.826 0.174 0.000
C17 Malignant neoplasm of small intestine
0.000 0.174 0.826
C44.2 Skin of ear and external auricular canal
0.825 0.175 0.000
G83.1 Monoplegia of lower limb
0.000 0.176 0.824
C44.3 Skin of other and unspecified parts of face
0.822 0.178 0.000
C77.0 Lymph nodes of head, face and neck
0.000 0.183 0.817
K90.9 Intestinal malabsorption, unspecified
0.000 0.184 0.816
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.185 0.815
E10.2 With renal complications
0.000 0.186 0.814
K90-K93 Other diseases of the digestive system
0.000 0.187 0.813
C80.9 Malignant neoplasm, unspecified
0.000 0.188 0.812
D07.2 Vagina
0.000 0.192 0.808
L80 Vitiligo
0.000 0.193 0.807
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.194 0.806
K51.0 Ulcerative (chronic) enterocolitis
0.805 0.195 0.000
Chapter XI Diseases of the digestive system
0.000 0.198 0.802
C22.9 Liver, unspecified
0.000 0.201 0.799
C77.4 Inguinal and lower limb lymph nodes
0.000 0.201 0.799
L50.0 Allergic urticaria
0.000 0.202 0.798
C91.1 Chronic lymphocytic leukaemia
0.000 0.205 0.795
H36.0 Diabetic retinopathy
0.000 0.207 0.793
C91 Lymphoid leukaemia
0.000 0.207 0.793
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.208 0.792
D64.8 Other specified anaemias
0.000 0.208 0.791
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.211 0.789
E11.5 With peripheral circulatory complications
0.000 0.212 0.788
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.212 0.787
C79 Secondary malignant neoplasm of other sites
0.000 0.213 0.787
E05.8 Other thyrotoxicosis
0.000 0.213 0.787
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.214 0.786
L89.2 Stage III decubitus ulcer
0.000 0.216 0.784
J45.0 Predominantly allergic asthma
0.000 0.219 0.781
E10.8 With unspecified complications
0.000 0.225 0.775
D52 Folate deficiency anaemia
0.000 0.225 0.775
C23 Malignant neoplasm of gallbladder
0.000 0.226 0.774
L50.9 Urticaria, unspecified
0.000 0.226 0.774
E14.8 With unspecified complications
0.000 0.226 0.774
E53.9 Vitamin B deficiency, unspecified
0.000 0.228 0.772
E22 Hyperfunction of pituitary gland
0.000 0.230 0.770
E21.3 Hyperparathyroidism, unspecified
0.000 0.230 0.770
D55-D59 Haemolytic anaemias
0.000 0.233 0.766
L88 Pyoderma gangrenosum
0.000 0.234 0.766
G82 Paraplegia and tetraplegia
0.000 0.237 0.763
E20.9 Hypoparathyroidism, unspecified
0.000 0.240 0.760
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.240 0.759
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.242 0.758
E14.5 With peripheral circulatory complications
0.000 0.244 0.756
C09 Malignant neoplasm of tonsil
0.000 0.245 0.755
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.247 0.753
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.248 0.752
C79.2 Secondary malignant neoplasm of skin
0.000 0.249 0.751
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.249 0.751
C34.9 Bronchus or lung, unspecified
0.000 0.250 0.750
L13 Other bullous disorders
0.000 0.251 0.749
L83 Acanthosis nigricans
0.000 0.251 0.749
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.254 0.746
H36 Retinal disorders in diseases classified elsewhere
0.000 0.257 0.743
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.258 0.742
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.260 0.740
E11.0 With coma
0.000 0.261 0.739
G03 Meningitis due to other and unspecified causes
0.000 0.265 0.735
E14.1 With ketoacidosis
0.000 0.266 0.734
C44.4 Skin of scalp and neck
0.732 0.268 0.000
K70-K77 Diseases of liver
0.000 0.273 0.727
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.274 0.726
C44.6 Skin of upper limb, including shoulder
0.725 0.275 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.278 0.722
E11.2 With renal complications
0.000 0.278 0.722
C34.1 Upper lobe, bronchus or lung
0.000 0.278 0.722
C77.8 Lymph nodes of multiple regions
0.000 0.280 0.720
C34.0 Main bronchus
0.000 0.281 0.719
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.281 0.719
C09.9 Tonsil, unspecified
0.000 0.281 0.719
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.282 0.718
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.283 0.717
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.283 0.717
D51.2 Transcobalamin II deficiency
0.000 0.283 0.717
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
D07.6 Other and unspecified male genital organs
0.000 0.283 0.717
D07.3 Other and unspecified female genital organs
0.000 0.283 0.717
D07.0 Endometrium
0.000 0.283 0.717
D06.7 Other parts of cervix
0.000 0.283 0.717
D06.1 Exocervix
0.000 0.283 0.717
D06.0 Endocervix
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E32 Diseases of thymus
0.000 0.283 0.716
E31 Polyglandular dysfunction
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.283 0.716
E27.0 Other adrenocortical overactivity
0.000 0.283 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.3 Other sideroblastic anaemias
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.285 0.715
L87 Transepidermal elimination disorders
0.000 0.285 0.715
L86 Keratoderma in diseases classified elsewhere
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.714
K75 Other inflammatory liver diseases
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.287 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.287 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.287 0.713
E16.3 Increased secretion of glucagon
0.000 0.287 0.713
D72 Other disorders of white blood cells
0.000 0.289 0.711
C21.2 Cloacogenic zone
0.000 0.290 0.710
L90.9 Atrophic disorder of skin, unspecified
0.000 0.290 0.710
L90.8 Other atrophic disorders of skin
0.000 0.290 0.710
L90.6 Striae atrophicae
0.000 0.290 0.710
L90.4 Acrodermatitis chronica atrophicans
0.000 0.290 0.710
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.290 0.710
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.290 0.710
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.290 0.710
C91.4 Hairy-cell leukaemia
0.000 0.291 0.709
E14.6 With other specified complications
0.000 0.291 0.709
H30-H36 Disorders of choroid and retina
0.000 0.293 0.707
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.294 0.706
E63 Other nutritional deficiencies
0.000 0.294 0.706
E56 Other vitamin deficiencies
0.000 0.294 0.706
E50 Vitamin A deficiency
0.000 0.294 0.706
E60 Dietary zinc deficiency
0.000 0.294 0.706
E59 Dietary selenium deficiency
0.000 0.294 0.706
E54 Ascorbic acid deficiency
0.000 0.294 0.706
E52 Niacin deficiency [pellagra]
0.000 0.294 0.706
E14.7 With multiple complications
0.000 0.294 0.706
E14.2 Withrenal complications
0.000 0.294 0.706
E14.0 With coma
0.000 0.294 0.706
K51.1 Ulcerative (chronic) ileocolitis
0.706 0.294 0.000
K75.4 Autoimmune hepatitis
0.000 0.294 0.706
L50.1 Idiopathic urticaria
0.000 0.295 0.705
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.295 0.705
D80-D89 Certain disorders involving the immune mechanism
0.000 0.296 0.704
E53.1 Pyridoxine deficiency
0.000 0.296 0.704
E53.0 Riboflavin deficiency
0.000 0.296 0.704
D50.1 Sideropenic dysphagia
0.000 0.296 0.704
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.296 0.703
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.296 0.703
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.297 0.703
G81.1 Spastic hemiplegia
0.000 0.297 0.703
L95.9 Vasculitis limited to skin, unspecified
0.000 0.297 0.703
E13 Other specified diabetes mellitus
0.000 0.299 0.701
L91.0 Keloid scar
0.000 0.300 0.700
G36 Other acute disseminated demyelination
0.000 0.302 0.698
D72.8 Other specified disorders of white blood cells
0.000 0.303 0.697
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.305 0.695
C17.9 Small intestine, unspecified
0.000 0.305 0.695
C44.5 Skin of trunk
0.695 0.305 0.000
C07 Malignant neoplasm of parotid gland
0.000 0.306 0.694
E14.4 With neurological complications
0.000 0.307 0.693
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.308 0.692
E58 Dietary calcium deficiency
0.000 0.308 0.692
Chapter VII Diseases of the eye and adnexa
0.000 0.310 0.690
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.310 0.690
E21.4 Other specified disorders of parathyroid gland
0.000 0.313 0.687
E21.2 Other hyperparathyroidism
0.000 0.313 0.687
D59 Acquired haemolytic anaemia
0.000 0.313 0.686
K90.3 Pancreatic steatorrhoea
0.000 0.315 0.685
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.315 0.685
K90.1 Tropical sprue
0.000 0.315 0.685
G83.4 Cauda equina syndrome
0.000 0.315 0.685
G00.8 Other bacterial meningitis
0.000 0.316 0.683
G00.3 Staphylococcal meningitis
0.000 0.316 0.683
G00.2 Streptococcal meningitis
0.000 0.316 0.683
G00.0 Haemophilus meningitis
0.000 0.316 0.683
E07 Other disorders of thyroid
0.000 0.317 0.683
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.319 0.681
L50.8 Other urticaria
0.000 0.319 0.681
G70-G73 Diseases of myoneural junction and muscle
0.000 0.319 0.681
G83.8 Other specified paralytic syndromes
0.000 0.320 0.680
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.321 0.679
E11.6 With other specified complications
0.000 0.323 0.677
G81.0 Flaccid hemiplegia
0.000 0.323 0.677
K90.8 Other intestinal malabsorption
0.000 0.324 0.676
G83.9 Paralytic syndrome, unspecified
0.000 0.325 0.675
C60-C63 Malignant neoplasms of male genital organs
0.000 0.327 0.673
E24 Cushing's syndrome
0.000 0.327 0.673
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.328 0.672
D86 Sarcoidosis
0.000 0.328 0.672
L95.8 Other vasculitis limited to skin
0.000 0.328 0.672
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.329 0.671
D09 Carcinoma in situ of other and unspecified sites
0.000 0.330 0.670
L13.0 Dermatitis herpetiformis
0.000 0.330 0.670
E25 Adrenogenital disorders
0.000 0.332 0.668
E11.8 With unspecified complications
0.000 0.336 0.664
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.336 0.664
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.336 0.664
C22.7 Other specified carcinomas of liver
0.000 0.336 0.663
C22.4 Other sarcomas of liver
0.000 0.336 0.663
C22.3 Angiosarcoma of liver
0.000 0.336 0.663
C22.2 Hepatoblastoma
0.000 0.336 0.663
E51 Thiamine deficiency
0.000 0.337 0.663
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.339 0.661
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.340 0.660
E34 Other endocrine disorders
0.000 0.342 0.658
N48 Other disorders of penis
0.000 0.342 0.658
C44.7 Skin of lower limb, including hip
0.657 0.343 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.343 0.657
G37.4 Subacute necrotising myelitis
0.000 0.343 0.657
G37.2 Central pontine myelinolysis
0.000 0.343 0.657
G37.1 Central demyelination of corpus callosum
0.000 0.343 0.657
G37.0 Diffuse sclerosis
0.000 0.343 0.657
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.344 0.655
N48.1 Balanoposthitis
0.000 0.345 0.655
L52 Erythema nodosum
0.000 0.345 0.655
G83.2 Monoplegia of upper limb
0.000 0.346 0.654
D05 Carcinoma in situ of breast
0.000 0.347 0.653
D53 Other nutritional anaemias
0.000 0.348 0.652
L12 Pemphigoid
0.000 0.348 0.651
L93 Lupus erythematosus
0.000 0.349 0.651
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.349 0.651
G83.5 Locked-in syndrome
0.000 0.351 0.648
G83.3 Monoplegia, unspecified
0.000 0.351 0.648
G83.0 Diplegia of upper limbs
0.000 0.351 0.648
D04 Carcinoma in situ of skin
0.000 0.353 0.647
C91.0 Acute lymphoblastic leukaemia
0.000 0.354 0.646
N48.6 Balanitis xerotica obliterans
0.000 0.354 0.646
L11 Other acantholytic disorders
0.000 0.355 0.645
K75.8 Other specified inflammatory liver diseases
0.000 0.356 0.644
C04 Malignant neoplasm of floor of mouth
0.000 0.356 0.644
L54 Erythema in diseases classified elsewhere
0.000 0.358 0.642
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.358 0.642
L20-L30 Dermatitis and eczema
0.000 0.360 0.640
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.363 0.637
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.368 0.632
L89.3 Stage IV decubitus ulcer
0.000 0.371 0.629
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.371 0.628
C31 Malignant neoplasm of accessory sinuses
0.000 0.371 0.628
C33 Malignant neoplasm of trachea
0.000 0.371 0.628
L50.6 Contact urticaria
0.000 0.374 0.626
L50.5 Cholinergic urticaria
0.000 0.374 0.626
L50.4 Vibratory urticaria
0.000 0.374 0.626
L50.3 Dermatographic urticaria
0.000 0.374 0.626
L50.2 Urticaria due to cold and heat
0.000 0.374 0.626
C17.0 Duodenum
0.000 0.379 0.621
C37 Malignant neoplasm of thymus
0.000 0.380 0.619
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.382 0.618
L14 Bullous disorders in diseases classified elsewhere
0.000 0.383 0.617
E20.8 Other hypoparathyroidism
0.000 0.383 0.617
E20.1 Pseudohypoparathyroidism
0.000 0.383 0.617
E20.0 Idiopathic hypoparathyroidism
0.000 0.383 0.617
G82.5 Tetraplegia, unspecified
0.000 0.383 0.617
G82.4 Spastic tetraplegia
0.000 0.384 0.616
K51.8 Other ulcerative colitis
0.616 0.384 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.386 0.614
E03.8 Other specified hypothyroidism
0.000 0.386 0.614
L94 Other localised connective tissue disorders
0.000 0.386 0.614
H31 Other disorders of choroid
0.000 0.387 0.613
G63.2 Diabetic polyneuropathy
0.000 0.388 0.612
J45.1 Nonallergic asthma
0.000 0.388 0.611
C34.3 Lower lobe, bronchus or lung
0.000 0.390 0.610
D59.1 Other autoimmune haemolytic anaemias
0.000 0.392 0.608
L95.1 Erythema elevatum diutinum
0.000 0.392 0.608
L95.0 Livedoid vasculitis
0.000 0.392 0.608
D50.8 Other iron deficiency anaemias
0.000 0.393 0.607
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.394 0.606
C12 Malignant neoplasm of pyriform sinus
0.000 0.395 0.605
C62 Malignant neoplasm of testis
0.000 0.396 0.604
U88 Agent resistant to multiple antibiotics
0.000 0.399 0.601
D05.1 Intraductal carcinoma in situ
0.000 0.401 0.599
C34.8 Overlapping lesion of bronchus and lung
0.000 0.401 0.599
G82.1 Spastic paraplegia
0.000 0.401 0.599
N48.4 Impotence of organic origin
0.000 0.403 0.597
J45.8 Mixed asthma
0.000 0.403 0.597
C17.1 Jejunum
0.000 0.404 0.596
K65-K67 Diseases of peritoneum
0.000 0.407 0.593
C44.8 Overlapping lesion of skin
0.592 0.408 0.000
C17.8 Overlapping lesion of small intestine
0.000 0.408 0.592
C17.3 Meckel's diverticulum
0.000 0.408 0.592
K73 Chronic hepatitis, not elsewhere classified
0.000 0.408 0.592
G06.2 Extradural and subdural abscess, unspecified
0.000 0.409 0.591
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.409 0.591
L91.9 Hypertrophic disorder of skin, unspecified
0.000 0.412 0.588
C43-C44 Melanoma and other malignant neoplasms of skin
0.342 0.413 0.245
K70 Alcoholic liver disease
0.000 0.414 0.586
C10 Malignant neoplasm of oropharynx
0.000 0.417 0.583
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.417 0.583
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.418 0.582
C93 Monocytic leukaemia
0.000 0.418 0.582
L10 Pemphigus
0.000 0.419 0.581
C17.2 Ileum
0.000 0.420 0.580
C01 Malignant neoplasm of base of tongue
0.000 0.421 0.579
G70 Myasthenia gravis and other myoneural disorders
0.000 0.421 0.579
C13 Malignant neoplasm of hypopharynx
0.000 0.422 0.578
E40-E46 Malnutrition
0.000 0.423 0.576
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.424 0.576
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.424 0.576
D86.0 Sarcoidosis of lung
0.000 0.427 0.573
D86.1 Sarcoidosis of lymph nodes
0.000 0.428 0.572
C00 Malignant neoplasm of lip
0.000 0.430 0.570
U80 Agent resistant to penicillin and related antibiotics
0.000 0.430 0.570
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.431 0.569
C11 Malignant neoplasm of nasopharynx
0.000 0.431 0.569
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.431 0.569
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.431 0.569
C91.7 Other lymphoid leukaemia
0.000 0.431 0.569
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.431 0.569
C91.3 Prolymphocytic leukaemia
0.000 0.431 0.569
C91.2 Subacute lymphocytic leukaemia
0.000 0.431 0.569
E06 Thyroiditis
0.000 0.432 0.568
E61 Deficiency of other nutrient elements
0.000 0.432 0.568
C22.0 Liver cell carcinoma
0.000 0.432 0.567
C95 Leukaemia of unspecified cell type
0.000 0.433 0.567
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.435 0.565
C94 Other leukaemias of specified cell type
0.000 0.435 0.565
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.437 0.563
D63.0 Anaemia in neoplastic disease
0.000 0.437 0.563
D86.9 Sarcoidosis, unspecified
0.000 0.438 0.562
L23 Allergic contact dermatitis
0.000 0.440 0.560
C32 Malignant neoplasm of larynx
0.000 0.440 0.560
C51-C58 Malignant neoplasms of female genital organs
0.000 0.441 0.559
E29 Testicular dysfunction
0.000 0.443 0.557
C86 Other specified types of T/NK-cell lymphoma
0.000 0.443 0.557
U89 Agent resistant to other and unspecified antibiotics
0.000 0.443 0.557
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.443 0.557
G03.9 Meningitis, unspecified
0.000 0.443 0.557
E34.0 Carcinoid syndrome
0.000 0.444 0.556
D52.8 Other folate deficiency anaemias
0.000 0.444 0.556
D52.1 Drug-induced folate deficiency anaemia
0.000 0.444 0.556
D52.0 Dietary folate deficiency anaemia
0.000 0.444 0.556
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.444 0.556
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.445 0.555
D00.0 Lip, oral cavity and pharynx
0.000 0.445 0.554
N48.0 Leukoplakia of penis
0.000 0.446 0.554
H31.0 Chorioretinal scars
0.000 0.447 0.553
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.447 0.552
E22.8 Other hyperfunction of pituitary gland
0.000 0.447 0.552
D07.5 Prostate
0.000 0.449 0.551
D57 Sickle-cell disorders
0.000 0.450 0.550
D55 Anaemia due to enzyme disorders
0.000 0.450 0.550
G06.1 Intraspinal abscess and granuloma
0.000 0.452 0.548
G82.3 Flaccid tetraplegia
0.000 0.453 0.547
G82.0 Flaccid paraplegia
0.000 0.453 0.547
C77.9 Lymph node, unspecified
0.000 0.455 0.545
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.456 0.544
C62.9 Testis, unspecified
0.000 0.456 0.544
D04.6 Skin of upper limb, including shoulder
0.000 0.457 0.543
C88 Malignant immunoproliferative diseases
0.000 0.458 0.542
C09.8 Overlapping lesion of tonsil
0.000 0.458 0.541
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.458 0.541
C09.0 Tonsillar fossa
0.000 0.458 0.541
G64 Other disorders of peripheral nervous system
0.000 0.460 0.539
D74 Methaemoglobinaemia
0.000 0.462 0.538
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.462 0.538
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.462 0.538
L13.9 Bullous disorder, unspecified
0.000 0.463 0.537
L13.8 Other specified bullous disorders
0.000 0.463 0.537
L13.1 Subcorneal pustular dermatitis
0.000 0.463 0.537
C76.0 Head, face and neck
0.000 0.463 0.537
H30 Chorioretinal inflammation
0.000 0.464 0.536
H35 Other retinal disorders
0.000 0.465 0.535
C91.9 Lymphoid leukaemia, unspecified
0.000 0.466 0.533
C44.9 Malignant neoplasm of skin, unspecified
0.533 0.467 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.467 0.533
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.468 0.532
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.468 0.532
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.468 0.532
L21 Seborrhoeic dermatitis
0.000 0.470 0.530
E55 Vitamin D deficiency
0.000 0.470 0.530
C04.9 Floor of mouth, unspecified
0.000 0.472 0.527
G03.8 Meningitis due to other specified causes
0.000 0.473 0.527
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.473 0.527
G03.1 Chronic meningitis
0.000 0.473 0.527
G03.0 Nonpyogenic meningitis
0.000 0.473 0.527
D86.8 Sarcoidosis of other and combined sites
0.000 0.474 0.526
L12.0 Bullous pemphigoid
0.000 0.475 0.525
D01.0 Colon
0.000 0.477 0.523
N48.2 Other inflammatory disorders of penis
0.000 0.477 0.522
E22.1 Hyperprolactinaemia
0.000 0.478 0.522
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.479 0.521

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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