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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17237098
log Bayes Factor = 8.24732
Chromosome 3   position 185,176,901  (GRCh37) Explore rs17237098 on Ensembl!
Variant rs17237098 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.997 0.003 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.995 0.005 0.000
R41.0 Disorientation, unspecified
0.991 0.009 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
R41.3 Other amnesia
0.985 0.015 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.979 0.021 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.970 0.030 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.967 0.033 0.000
F31 Bipolar affective disorder
0.966 0.034 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.958 0.042 0.000
E70-E90 Metabolic disorders
0.957 0.043 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.955 0.045 0.000
F33 Recurrent depressive disorder
0.952 0.048 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
E83 Disorders of mineral metabolism
0.943 0.057 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.941 0.059 0.000
F29 Unspecified nonorganic psychosis
0.938 0.062 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.935 0.065 0.000
F60-F69 Disorders of adult personality and behaviour
0.933 0.067 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.925 0.075 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.922 0.078 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.921 0.079 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.915 0.085 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.914 0.086 0.000
C79 Secondary malignant neoplasm of other sites
0.913 0.087 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.909 0.091 0.000
E83.1 Disorders of iron metabolism
0.908 0.092 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.907 0.093 0.000
G90-G99 Other disorders of the nervous system
0.903 0.097 0.000
F41 Other anxiety disorders
0.902 0.098 0.000
E20-E35 Disorders of other endocrine glands
0.899 0.101 0.000
T79-T79 Certain early complications of trauma
0.898 0.102 0.000
E87.7 Fluid overload
0.898 0.102 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.894 0.106 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.893 0.107 0.000
F41.9 Anxiety disorder, unspecified
0.893 0.107 0.000
Y52 Agents primarily affecting the cardiovascular system
0.891 0.109 0.000
E85 Amyloidosis
0.890 0.110 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.890 0.110 0.000
S20-S29 Injuries to the thorax
0.889 0.111 0.000
C80 Malignant neoplasm without specification of site
0.885 0.115 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.880 0.120 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.878 0.122 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.878 0.122 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.874 0.126 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.872 0.128 0.000
Q60-Q64 Congenital malformations of the urinary system
0.871 0.129 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.868 0.132 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.862 0.138 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.860 0.140 0.000
G93 Other disorders of brain
0.860 0.140 0.000
C77.5 Intrapelvic lymph nodes
0.859 0.141 0.000
C77.3 Axillary and upper limb lymph nodes
0.856 0.144 0.000
F99-F99 Unspecified mental disorder
0.855 0.145 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.852 0.148 0.000
C91 Lymphoid leukaemia
0.849 0.151 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.849 0.151 0.000
E83.4 Disorders of magnesium metabolism
0.844 0.156 0.000
S10-S19 Injuries to the neck
0.843 0.157 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.843 0.157 0.000
Chapter XXII Codes for special purposes
0.842 0.158 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.842 0.158 0.000
F60 Specific personality disorders
0.838 0.162 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.836 0.164 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.833 0.167 0.000
E87.6 Hypokalaemia
0.830 0.170 0.000
F33.9 Recurrent depressive disorder, unspecified
0.830 0.170 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.828 0.171 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.828 0.172 0.000
Y57 Other and unspecified drugs and medicaments
0.826 0.174 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.825 0.175 0.000
X50-X57 Overexertion, travel and privation
0.823 0.177 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.823 0.177 0.000
Y44 Agents primarily affecting blood constituents
0.822 0.178 0.000
R41.2 Retrograde amnesia
0.822 0.178 0.000
E85.4 Organ-limited amyloidosis
0.821 0.179 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.820 0.180 0.000
D69 Purpura and other haemorrhagic conditions
0.820 0.180 0.000
T14 Injury of unspecified body region
0.816 0.184 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.816 0.184 0.000
F40 Phobic anxiety disorders
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.810 0.190 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
Q61 Cystic kidney disease
0.807 0.193 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.807 0.193 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.806 0.194 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.805 0.194 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.805 0.195 0.000
G70-G73 Diseases of myoneural junction and muscle
0.805 0.195 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.804 0.196 0.000
R45 Symptoms and signs involving emotional state
0.803 0.197 0.000
G40-G47 Episodic and paroxysmal disorders
0.803 0.197 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.802 0.198 0.000
S40-S49 Injuries to the shoulder and upper arm
0.802 0.198 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.801 0.199 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.799 0.201 0.000
D70 Agranulocytosis
0.798 0.202 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.797 0.203 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.795 0.205 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.795 0.205 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.794 0.206 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.792 0.208 0.000
F31.9 Bipolar affective disorder, unspecified
0.791 0.209 0.000
C85.1 B-cell lymphoma, unspecified
0.790 0.210 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.789 0.211 0.000
E87.5 Hyperkalaemia
0.787 0.213 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.785 0.215 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.784 0.216 0.000
C77.4 Inguinal and lower limb lymph nodes
0.783 0.217 0.000
Q00-Q07 Congenital malformations of the nervous system
0.782 0.218 0.000
Q80-Q89 Other congenital malformations
0.782 0.218 0.000
F34 Persistent mood [affective] disorders
0.781 0.219 0.000
F30 Manic episode
0.781 0.219 0.000
F32 Depressive episode
0.780 0.220 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.779 0.221 0.000
C77.2 Intra-abdominal lymph nodes
0.779 0.221 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.777 0.223 0.000
Y52.1 Calcium-channel blockers
0.777 0.223 0.000
C90.0 Multiple myeloma
0.775 0.225 0.000
T66-T78 Other and unspecified effects of external causes
0.774 0.226 0.000
R44.0 Auditory hallucinations
0.774 0.226 0.000
F20 Schizophrenia
0.773 0.227 0.000
Y48 Anaesthetics and therapeutic gases
0.768 0.231 0.000
R40 Somnolence, stupor and coma
0.767 0.233 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.762 0.237 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.761 0.238 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.761 0.239 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.760 0.240 0.000
Y00-Y09 Assault
0.757 0.243 0.000
F45 Somatoform disorders
0.754 0.246 0.000
V10-V19 Pedal cyclist injured in transport accident
0.754 0.246 0.000
G93.9 Disorder of brain, unspecified
0.754 0.246 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.753 0.247 0.000
V40-V49 Car occupant injured in transport accident
0.752 0.248 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.751 0.249 0.000
F99 Mental disorder, not otherwise specified
0.751 0.249 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.749 0.251 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.749 0.251 0.000
F69 Unspecified disorder of adult personality and behaviour
0.745 0.255 0.000
T51 Toxic effect of alcohol
0.745 0.255 0.000
C91.1 Chronic lymphocytic leukaemia
0.745 0.255 0.000
F64 Gender identity disorders
0.744 0.256 0.000
R46 Symptoms and signs involving appearance and behaviour
0.744 0.256 0.000
S32 Fracture of lumbar spine and pelvis
0.742 0.258 0.000
F22 Persistent delusional disorders
0.741 0.259 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.741 0.259 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.740 0.260 0.000
F80-F89 Disorders of psychological development
0.738 0.262 0.000
D69.6 Thrombocytopenia, unspecified
0.737 0.263 0.000
E29 Testicular dysfunction
0.737 0.263 0.000
Y40 Systemic antibiotics
0.736 0.263 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.736 0.264 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.736 0.264 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.735 0.265 0.000
T14.0 Superficial injury of unspecified body region
0.735 0.265 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.734 0.266 0.000
E83.3 Disorders of phosphorus metabolism
0.733 0.267 0.000
R25 Abnormal involuntary movements
0.731 0.269 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.730 0.270 0.000
F43 Reaction to severe stress, and adjustment disorders
0.730 0.270 0.000
C83.0 Small cell (diffuse)
0.730 0.270 0.000
Q61.0 Congenital single renal cyst
0.729 0.271 0.000
E22 Hyperfunction of pituitary gland
0.729 0.271 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.729 0.271 0.000
T00-T07 Injuries involving multiple body regions
0.727 0.273 0.000
D66 Hereditary factor VIII deficiency
0.726 0.274 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.724 0.276 0.000
E87.0 Hyperosmolality and hypernatraemia
0.723 0.277 0.000
S20 Superficial injury of thorax
0.723 0.277 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.722 0.278 0.000
C92 Myeloid leukaemia
0.722 0.278 0.000
G43 Migraine
0.721 0.279 0.000
Y57.8 Other drugs and medicaments
0.718 0.282 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.718 0.282 0.000
C15-C26 Malignant neoplasms of digestive organs
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
E85.9 Amyloidosis, unspecified
0.716 0.283 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
R41.1 Anterograde amnesia
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.715 0.285 0.000
F39 Unspecified mood [affective] disorder
0.715 0.285 0.000
G93.4 Encephalopathy, unspecified
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
C95 Leukaemia of unspecified cell type
0.714 0.286 0.000
C94 Other leukaemias of specified cell type
0.714 0.286 0.000
C93 Monocytic leukaemia
0.714 0.286 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.286 0.000
R43 Disturbances of smell and taste
0.713 0.287 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.713 0.287 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.711 0.288 0.000
F60.9 Personality disorder, unspecified
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
C83.3 Large cell (diffuse)
0.711 0.289 0.000
F60.3 Emotionally unstable personality disorder
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Y44.2 Anticoagulants
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.709 0.291 0.000
F42 Obsessive-compulsive disorder
0.709 0.291 0.000
C84.5 Other and unspecified T-cell lymphomas
0.708 0.292 0.000
X41.9 Unspecified place
0.707 0.292 0.000
R44.3 Hallucinations, unspecified
0.707 0.293 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.707 0.293 0.000
S12 Fracture of neck
0.707 0.293 0.000
T79.7 Traumatic subcutaneous emphysema
0.706 0.294 0.000
X51 Travel and motion
0.704 0.296 0.000
F40.2 Specific (isolated) phobias
0.704 0.296 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.704 0.296 0.000
Y45.0 Opioids and related analgesics
0.703 0.297 0.000
E21.3 Hyperparathyroidism, unspecified
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.298 0.000
Y58 Bacterial vaccines
0.702 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.702 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
F25 Schizoaffective disorders
0.700 0.300 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.698 0.301 0.000
C79.2 Secondary malignant neoplasm of skin
0.698 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
F32.0 Mild depressive episode
0.697 0.303 0.000
T91 Sequelae of injuries of neck and trunk
0.697 0.303 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.696 0.303 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
F28 Other nonorganic psychotic disorders
0.695 0.305 0.000
F24 Induced delusional disorder
0.695 0.305 0.000
F21 Schizotypal disorder
0.695 0.305 0.000
T23 Burn and corrosion of wrist and hand
0.695 0.305 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.694 0.306 0.000
F48 Other neurotic disorders
0.694 0.306 0.000
F44 Dissociative [conversion] disorders
0.694 0.306 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.693 0.307 0.000
F31.8 Other bipolar affective disorders
0.692 0.308 0.000
F31.7 Bipolar affective disorder, currently in remission
0.692 0.308 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.692 0.308 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.692 0.308 0.000
C88 Malignant immunoproliferative diseases
0.691 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.690 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.689 0.311 0.000
Y45.2 Propionic acid derivatives
0.689 0.311 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.689 0.311 0.000
E83.5 Disorders of calcium metabolism
0.689 0.311 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.313 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.313 0.000
T42.1 Iminostilbenes
0.686 0.313 0.000
Y45.5 4-Aminophenol derivatives
0.686 0.314 0.000
S36 Injury of intra-abdominal organs
0.686 0.314 0.000
E84 Cystic fibrosis
0.686 0.314 0.000
E79 Disorders of purine and pyrimidine metabolism
0.686 0.314 0.000
E77 Disorders of glycoprotein metabolism
0.686 0.314 0.000
E76 Disorders of glycosaminoglycan metabolism
0.686 0.314 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.686 0.314 0.000
E74 Other disorders of carbohydrate metabolism
0.686 0.314 0.000
E73 Lactose intolerance
0.686 0.314 0.000
E72 Other disorders of amino-acid metabolism
0.686 0.314 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.686 0.314 0.000
E70 Disorders of aromatic amino-acid metabolism
0.686 0.314 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.686 0.314 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.686 0.314 0.000
Q61.2 Polycystic kidney, adult type
0.686 0.314 0.000
S22.4 Multiple fractures of ribs
0.686 0.314 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.685 0.315 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.685 0.315 0.000
C85.0 Lymphosarcoma
0.685 0.315 0.000
T43.2 Other and unspecified antidepressants
0.684 0.316 0.000
F33.8 Other recurrent depressive disorders
0.683 0.317 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.683 0.317 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.683 0.317 0.000
L60-L75 Disorders of skin appendages
0.682 0.318 0.000
G72 Other myopathies
0.681 0.319 0.000
C81 Hodgkin's disease
0.681 0.319 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.680 0.320 0.000
E34 Other endocrine disorders
0.680 0.320 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.680 0.320 0.000
C82.0 Small cleaved cell, follicular
0.679 0.321 0.000
T21 Burn and corrosion of trunk
0.679 0.321 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.678 0.322 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.678 0.322 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.677 0.323 0.000
R45.1 Restlessness and agitation
0.677 0.323 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.676 0.324 0.000
E83.8 Other disorders of mineral metabolism
0.676 0.324 0.000
E83.2 Disorders of zinc metabolism
0.676 0.324 0.000
E83.0 Disorders of copper metabolism
0.676 0.324 0.000
T16 Foreign body in ear
0.676 0.324 0.000
Chapter I Certain infectious and parasitic diseases
0.674 0.326 0.000
E21.0 Primary hyperparathyroidism
0.674 0.326 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.674 0.326 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.673 0.327 0.000
S22.5 Flail chest
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.671 0.328 0.000
G91 Hydrocephalus
0.671 0.329 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.671 0.329 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.670 0.330 0.000
F68 Other disorders of adult personality and behaviour
0.669 0.331 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.669 0.331 0.000
F65 Disorders of sexual preference
0.669 0.331 0.000
F63 Habit and impulse disorders
0.669 0.331 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.669 0.331 0.000
F61 Mixed and other personality disorders
0.669 0.331 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.667 0.333 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.666 0.333 0.000
C79.6 Secondary malignant neoplasm of ovary
0.665 0.335 0.000
R20 Disturbances of skin sensation
0.665 0.335 0.000
G95 Other diseases of spinal cord
0.665 0.335 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.664 0.336 0.000
E87.4 Mixed disorder of acid-base balance
0.663 0.336 0.000
Chapter VIII Diseases of the ear and mastoid process
0.663 0.337 0.000
R87 Abnormal findings in specimens from female genital organs
0.663 0.337 0.000
L72.1 Trichilemmal cyst
0.662 0.338 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.662 0.338 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.662 0.338 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.662 0.338 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.662 0.338 0.000
T43.9 Psychotropic drug, unspecified
0.661 0.339 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
T43.6 Psychostimulants with abuse potential
0.661 0.339 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.661 0.339 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.661 0.339 0.000
T14.9 Injury, unspecified
0.659 0.341 0.000
R77 Other abnormalities of plasma proteins
0.657 0.343 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
G93.6 Cerebral oedema
0.657 0.343 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.656 0.344 0.000
G71 Primary disorders of muscles
0.656 0.344 0.000
R44.2 Other hallucinations
0.656 0.344 0.000
C90.2 Plasmacytoma, extramedullary
0.656 0.344 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.655 0.344 0.000
S37 Injury of urinary and pelvic organs
0.655 0.344 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.655 0.344 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.655 0.344 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.655 0.344 0.000
S31 Open wound of abdomen, lower back and pelvis
0.655 0.344 0.000
S27 Injury of other and unspecified intrathoracic organs
0.655 0.345 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.654 0.345 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.654 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.654 0.345 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.654 0.346 0.000
G93.8 Other specified disorders of brain
0.654 0.346 0.000
C11 Malignant neoplasm of nasopharynx
0.654 0.346 0.000
G93.2 Benign intracranial hypertension
0.654 0.346 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.653 0.347 0.000
D69.0 Allergic purpura
0.653 0.347 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.651 0.348 0.000
D00-D09 In situ neoplasms
0.651 0.349 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.651 0.349 0.000
T13 Other injuries of lower limb, level unspecified
0.649 0.350 0.000
S22.1 Multiple fractures of thoracic spine
0.649 0.350 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.649 0.351 0.000
E28 Ovarian dysfunction
0.649 0.351 0.000
C51-C58 Malignant neoplasms of female genital organs
0.649 0.351 0.000
T18 Foreign body in alimentary tract
0.649 0.351 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.648 0.352 0.000
Y42.5 Other oestrogens and progestogens
0.648 0.352 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.648 0.352 0.000
G92 Toxic encephalopathy
0.648 0.352 0.000
C80.9 Malignant neoplasm, unspecified
0.647 0.353 0.000
T79.6 Traumatic ischaemia of muscle
0.647 0.353 0.000
F41.8 Other specified anxiety disorders
0.647 0.353 0.000
F41.3 Other mixed anxiety disorders
0.647 0.353 0.000
T51.9 Alcohol, unspecified
0.647 0.353 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.646 0.354 0.000
F23 Acute and transient psychotic disorders
0.645 0.354 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.645 0.355 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.645 0.355 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.644 0.355 0.000
E32 Diseases of thymus
0.644 0.355 0.000
E31 Polyglandular dysfunction
0.644 0.355 0.000
E30 Disorders of puberty, not elsewhere classified
0.644 0.355 0.000
E26 Hyperaldosteronism
0.644 0.355 0.000
E25 Adrenogenital disorders
0.644 0.355 0.000
E24 Cushing's syndrome
0.644 0.355 0.000
E20 Hypoparathyroidism
0.644 0.355 0.000
F05.9 Delirium, unspecified
0.644 0.356 0.000
T11 Other injuries of upper limb, level unspecified
0.641 0.359 0.000
T09 Other injuries of spine and trunk, level unspecified
0.641 0.359 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.641 0.359 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.641 0.359 0.000
T12 Fracture of lower limb, level unspecified
0.641 0.359 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.641 0.359 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.641 0.359 0.000
T10 Fracture of upper limb, level unspecified
0.641 0.359 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.641 0.359 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.641 0.359 0.000
T08 Fracture of spine, level unspecified
0.641 0.359 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.641 0.359 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.640 0.360 0.000
X48 Accidental poisoning by and exposure to pesticides
0.640 0.360 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.640 0.360 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.640 0.360 0.000
X45 Accidental poisoning by and exposure to alcohol
0.640 0.360 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.640 0.360 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.640 0.360 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.640 0.360 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.640 0.360 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.639 0.361 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.639 0.361 0.000
Y52.7 Peripheral vasodilators
0.639 0.361 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.639 0.361 0.000
E85.8 Other amyloidosis
0.638 0.362 0.000
E85.3 Secondary systemic amyloidosis
0.638 0.362 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.638 0.362 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.638 0.362 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.638 0.362 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.638 0.362 0.000
Y65 Other misadventures during surgical and medical care
0.638 0.362 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.638 0.362 0.000
C83.7 Burkitt's tumour
0.638 0.362 0.000
C83.6 Undifferentiated (diffuse)
0.638 0.362 0.000
C83.5 Lymphoblastic (diffuse)
0.638 0.362 0.000
C83.4 Immunoblastic (diffuse)
0.638 0.362 0.000
C83.2 Mixed small and large cell (diffuse)
0.638 0.362 0.000
C83.1 Small cleaved cell (diffuse)
0.638 0.362 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.637 0.363 0.000
S26 Injury of heart
0.637 0.363 0.000
S25 Injury of blood vessels of thorax
0.637 0.363 0.000
S24 Injury of nerves and spinal cord at thorax level
0.637 0.363 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.637 0.363 0.000
S21 Open wound of thorax
0.637 0.363 0.000
R44.1 Visual hallucinations
0.636 0.364 0.000
Q05 Spina bifida
0.636 0.364 0.000
C77.8 Lymph nodes of multiple regions
0.636 0.364 0.000
S19 Other and unspecified injuries of neck
0.635 0.365 0.000
R79 Other abnormal findings of blood chemistry
0.635 0.365 0.000
G93.3 Postviral fatigue syndrome
0.635 0.365 0.000
C77.0 Lymph nodes of head, face and neck
0.634 0.366 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.633 0.367 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.633 0.367 0.000
Q63 Other congenital malformations of kidney
0.633 0.367 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.631 0.369 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.631 0.369 0.000
Y45.8 Other analgesics and antipyretics
0.631 0.369 0.000
Y45.4 Antirheumatics
0.631 0.369 0.000
R82 Other abnormal findings in urine
0.631 0.369 0.000
X60-X84 Intentional self-harm
0.631 0.369 0.000
G83 Other paralytic syndromes
0.630 0.370 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.630 0.370 0.000
Q85 Phakomatoses, not elsewhere classified
0.629 0.370 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.629 0.371 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.629 0.371 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.629 0.371 0.000
T42.3 Barbiturates
0.629 0.371 0.000
T42.2 Succinimides and oxazolidinediones
0.629 0.371 0.000
T42.0 Hydantoin derivatives
0.629 0.371 0.000
F01 Vascular dementia
0.629 0.371 0.000
Y57.5 X-ray contrast media
0.629 0.371 0.000
R25.1 Tremor, unspecified
0.628 0.372 0.000
Y95 Nosocomial condition
0.627 0.373 0.000
F34.1 Dysthymia
0.627 0.373 0.000
C90.3 Solitary plasmacytoma
0.626 0.373 0.000
C90.1 Plasma cell leukaemia
0.626 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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