TreeWAS – Variant ID: rs17398575

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.930	0.070	0.000
I10-I15 Hypertensive diseases	0.879	0.121	0.000
I12 Hypertensive renal disease	0.875	0.125	0.000
I12.0 Hypertensive renal disease with renal failure	0.874	0.126	0.000
I13 Hypertensive heart and renal disease	0.692	0.308	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.558	0.442	0.000
I11 Hypertensive heart disease	0.541	0.459	0.000
I12.9 Hypertensive renal disease without renal failure	0.540	0.460	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.496	0.504	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.496	0.504	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.496	0.504	0.000
I15 Secondary hypertension	0.396	0.603	0.001
I65.2 Occlusion and stenosis of carotid artery	0.369	0.631	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.364	0.636	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.331	0.669	0.000
I15.8 Other secondary hypertension	0.284	0.715	0.001
I15.2 Hypertension secondary to endocrine disorders	0.284	0.715	0.001
I15.0 Renovascular hypertension	0.281	0.718	0.001
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.216	0.784	0.000
I15.9 Seconday hypertension, unspecified	0.213	0.787	0.001
I15.1 Hypertension secondary to other renal disorders	0.189	0.810	0.001
I65.0 Occlusion and stenosis of vertebral artery	0.172	0.828	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.156	0.844	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.155	0.845	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.155	0.845	0.000
I65.1 Occlusion and stenosis of basilar artery	0.155	0.845	0.000
G93 Other disorders of brain	0.000	0.850	0.150
G93.8 Other specified disorders of brain	0.000	0.855	0.145
G93.9 Disorder of brain, unspecified	0.000	0.858	0.142
G93.3 Postviral fatigue syndrome	0.000	0.865	0.135
G93.4 Encephalopathy, unspecified	0.000	0.865	0.135
G90-G99 Other disorders of the nervous system	0.000	0.870	0.130
A04.8 Other specified bacterial intestinal infections	0.000	0.872	0.128
G93.0 Cerebral cysts	0.000	0.875	0.125
G95 Other diseases of spinal cord	0.000	0.878	0.122
G95.9 Disease of spinal cord, unspecified	0.000	0.879	0.121
G93.6 Cerebral oedema	0.000	0.880	0.120
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.889	0.111
G93.7 Reye's syndrome	0.000	0.892	0.108
G96 Other disorders of central nervous system	0.000	0.893	0.107
G93.5 Compression of brain	0.000	0.900	0.100
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.900	0.100
I24.8 Other forms of acute ischaemic heart disease	0.099	0.901	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.901	0.099
G95.1 Vascular myelopathies	0.000	0.904	0.096
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.905	0.095
G97.8 Other postprocedural disorders of nervous system	0.000	0.905	0.095
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.906	0.094
G92 Toxic encephalopathy	0.000	0.907	0.093
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.913	0.087
G90 Disorders of autonomic nervous system	0.000	0.914	0.086
G96.8 Other specified disorders of central nervous system	0.000	0.915	0.085
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.917	0.083
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.919	0.081
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.919	0.081
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.920	0.080
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.920	0.080
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.922	0.078
G91 Hydrocephalus	0.000	0.923	0.077
G96.9 Disorder of central nervous system, unspecified	0.000	0.923	0.077
G93.2 Benign intracranial hypertension	0.000	0.927	0.073
G95.8 Other specified diseases of spinal cord	0.000	0.928	0.072
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.928	0.072
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.928	0.072
G94.1 Hydrocephalus in neoplastic disease	0.000	0.928	0.072
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.928	0.072
Chapter IX Diseases of the circulatory system	0.071	0.929	0.000
I24 Other acute ischaemic heart diseases	0.070	0.930	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.930	0.070
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.934	0.066
I20-I25 Ischaemic heart diseases	0.066	0.934	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.934	0.066
I77 Other disorders of arteries and arterioles	0.064	0.936	0.000
A04 Other bacterial intestinal infections	0.000	0.936	0.064
I70-I79 Diseases of arteries, arterioles and capillaries	0.064	0.936	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.937	0.063
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.937	0.063
G90.4 Autonomic dysreflexia	0.000	0.938	0.062
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.938	0.062
G90.8 Other disorders of autonomic nervous system	0.000	0.938	0.062
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.938	0.062
I70 Atherosclerosis	0.061	0.939	0.000
I60-I69 Cerebrovascular diseases	0.061	0.939	0.000
G90.3 Multisystem degeneration	0.000	0.939	0.061
I77.8 Other specified disorders of arteries and arterioles	0.059	0.941	0.000
I25.1 Atherosclerotic heart disease	0.059	0.941	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.943	0.057
I70.2 Atherosclerosis of arteries of the extremities	0.057	0.943	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.943	0.057
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.944	0.055
I77.1 Stricture of artery	0.055	0.945	0.000
A00-A09 Intestinal infectious diseases	0.000	0.945	0.055
I00-I02 Acute rheumatic fever	0.054	0.946	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.946	0.054
I77.0 Arteriovenous fistula, acquired	0.054	0.946	0.000
A04.9 Bacterial intestinal infection, unspecified	0.000	0.946	0.054
I77.9 Disorder of arteries and arterioles, unspecified	0.054	0.946	0.000
G91.8 Other hydrocephalus	0.000	0.948	0.051
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.051	0.949	0.000
I70.1 Atherosclerosis of renal artery	0.049	0.950	0.000
I70.0 Atherosclerosis of aorta	0.049	0.950	0.000
I77.6 Arteritis, unspecified	0.049	0.951	0.000
I22 Subsequent myocardial infarction	0.048	0.952	0.000
I62 Other nontraumatic intracranial haemorrhage	0.048	0.952	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.048	0.952	0.000
I72 Other aneurysm	0.047	0.953	0.000
A04.4 Other intestinal Escherichia coli infections	0.000	0.953	0.047
I77.5 Necrosis of artery	0.046	0.954	0.000
I77.4 Coeliac artery compression syndrome	0.046	0.954	0.000
I77.3 Arterial fibromuscular dysplasia	0.046	0.954	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.954	0.046
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.954	0.046
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.954	0.046
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.954	0.046
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.954	0.046
I70.9 Generalised and unspecified atherosclerosis	0.045	0.955	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.045	0.955	0.000
I70.8 Atherosclerosis of other arteries	0.045	0.955	0.000
I24.1 Dressler's syndrome	0.044	0.955	0.000
I20 Angina pectoris	0.044	0.956	0.000
G90.2 Horner's syndrome	0.000	0.956	0.043
I77.2 Rupture of artery	0.043	0.957	0.000
G91.0 Communicating hydrocephalus	0.000	0.957	0.043
I22.8 Subsequent myocardial infarction of other sites	0.042	0.958	0.000
I25 Chronic ischaemic heart disease	0.042	0.958	0.000
I72.8 Aneurysm of other specified arteries	0.042	0.958	0.000
G91.1 Obstructive hydrocephalus	0.000	0.958	0.042
I20.9 Angina pectoris, unspecified	0.042	0.958	0.000
I00 Rheumatic fever without mention of heart involvement	0.041	0.958	0.000
I72.0 Aneurysm of carotid artery	0.041	0.959	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.041	0.959	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.041	0.959	0.000
I23 Certain current complications following acute myocardial infarction	0.040	0.960	0.000
A05 Other bacterial foodborne intoxications	0.000	0.960	0.040
I68 Cerebrovascular disorders in diseases classified elsewhere	0.039	0.960	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.039	0.960	0.000
A06 Amoebiasis	0.000	0.961	0.039
A03 Shigellosis	0.000	0.961	0.039
A01 Typhoid and paratyphoid fevers	0.000	0.961	0.039
A00 Cholera	0.000	0.961	0.039
A02 Other Salmonella infections	0.000	0.961	0.039
I02 Rheumatic chorea	0.039	0.961	0.000
I01 Rheumatic fever with heart involvement	0.039	0.961	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.039	0.961	0.000
G95.2 Cord compression, unspecified	0.000	0.961	0.039
I62.1 Nontraumatic extradural haemorrhage	0.038	0.962	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.038	0.962	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.963	0.037
I73 Other peripheral vascular diseases	0.037	0.963	0.000
I72.1 Aneurysm of artery of upper extremity	0.036	0.964	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.036	0.964	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.036	0.964	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.035	0.965	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.034	0.966	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.034	0.966	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.034	0.966	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.033	0.967	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.032	0.967	0.000
A07 Other protozoal intestinal diseases	0.000	0.968	0.032
I70.81 Atherosclerosis of other arteries (with gangrene)	0.032	0.968	0.000
I74 Arterial embolism and thrombosis	0.032	0.968	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.032	0.968	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.032	0.968	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.031	0.969	0.000
I72.9 Aneurysm of unspecified site	0.031	0.969	0.000
I25.6 Silent myocardial ischaemia	0.030	0.969	0.000
I60 Subarachnoid haemorrhage	0.030	0.970	0.000
A05.9 Bacterial foodborne intoxication, unspecified	0.000	0.970	0.030
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.029	0.971	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.029	0.971	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.029	0.971	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.029	0.971	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.029	0.971	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.029	0.971	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.029	0.971	0.000
A05.8 Other specified bacterial foodborne intoxications	0.000	0.971	0.029
A05.4 Foodborne Bacillus cereus intoxication	0.000	0.971	0.029
A05.3 Foodborne Vibrio parahaemolyticus intoxication	0.000	0.971	0.029
A05.2 Foodborne Clostridium perfringens [Clostridium welchii] intoxication	0.000	0.971	0.029
A05.1 Botulism	0.000	0.971	0.029
A05.0 Foodborne staphylococcal intoxication	0.000	0.971	0.029
I64 Stroke, not specified as haemorrhage or infarction	0.029	0.971	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.029	0.971	0.000
A08 Viral and other specified intestinal infections	0.000	0.971	0.029
I20.8 Other forms of angina pectoris	0.029	0.971	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.028	0.971	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.028	0.971	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.028	0.971	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.028	0.971	0.000
I79.1 Aortitis in diseases classified elsewhere	0.028	0.971	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.028	0.971	0.000
A00.9 Cholera, unspecified	0.000	0.971	0.028
A00.1 Cholera due to Vibrio cholerae 01, biovar el tor	0.000	0.971	0.028
A00.0 Cholera due to Vibrio cholerae 01, biovar cholerae	0.000	0.971	0.028
A01.4 Paratyphoid fever, unspecified	0.000	0.971	0.028
A01.3 Paratyphoid fever C	0.000	0.971	0.028
A01.2 Paratyphoid fever B	0.000	0.971	0.028
A01.1 Paratyphoid fever A	0.000	0.971	0.028
A01.0 Typhoid fever	0.000	0.971	0.028
A03.9 Shigellosis, unspecified	0.000	0.971	0.028
A03.8 Other shigellosis	0.000	0.971	0.028
A03.3 Shigellosis due to Shigella sonnei	0.000	0.971	0.028
A03.2 Shigellosis due to Shigella boydii	0.000	0.971	0.028
A03.1 Shigellosis due to Shigella flexneri	0.000	0.971	0.028
A03.0 Shigellosis due to Shigella dysenteriae	0.000	0.971	0.028
A06.9 Amoebiasis, unspecified	0.000	0.971	0.028
A06.8 Amoebic infection of other sites	0.000	0.971	0.028
A06.7 Cutaneous amoebiasis	0.000	0.971	0.028
A06.6 Amoebic brain abscess	0.000	0.971	0.028
A06.5 Amoebic lung abscess	0.000	0.971	0.028
A06.4 Amoebic liver abscess	0.000	0.971	0.028
A06.3 Amoeboma of intestine	0.000	0.971	0.028
A06.2 Amoebic nondysenteric colitis	0.000	0.971	0.028
A06.1 Chronic intestinal amoebiasis	0.000	0.971	0.028
A06.0 Acute amoebic dysentery	0.000	0.971	0.028
A02.9 Salmonella infection, unspecified	0.000	0.972	0.028
A02.8 Other specified Salmonella infections	0.000	0.972	0.028
A02.2 Localised Salmonella infections	0.000	0.972	0.028
A02.1 Salmonella septicaemia	0.000	0.972	0.028
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.028	0.972	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.028	0.972	0.000
I01.8 Other acute rheumatic heart disease	0.028	0.972	0.000
I01.2 Acute rheumatic myocarditis	0.028	0.972	0.000
I01.1 Acute rheumatic endocarditis	0.028	0.972	0.000
I01.0 Acute rheumatic pericarditis	0.028	0.972	0.000
I02.9 Rheumatic chorea without heart involvement	0.028	0.972	0.000
I02.0 Rheumatic chorea with heart involvement	0.028	0.972	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.028	0.972	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.028	0.972	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.028	0.972	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.028	0.972	0.000
A02.0 Salmonella gastro-enteritis	0.000	0.972	0.028
I73.8 Other specified peripheral vascular diseases	0.028	0.972	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.028	0.972	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.027	0.973	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.027	0.973	0.000
I74.8 Embolism and thrombosis of other arteries	0.026	0.974	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.974	0.026
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.025	0.975	0.000
I72.4 Aneurysm of artery of lower extremity	0.025	0.975	0.000
I72.2 Aneurysm of renal artery	0.025	0.975	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.025	0.975	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.025	0.975	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.024	0.975	0.000
I68.0 Cerebral amyloid angiopathy	0.024	0.976	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.024	0.976	0.000
A07.9 Protozoal intestinal disease, unspecified	0.000	0.977	0.023
A07.8 Other specified protozoal intestinal diseases	0.000	0.977	0.023
A07.3 Isosporiasis	0.000	0.977	0.023
A07.2 Cryptosporidiosis	0.000	0.977	0.023
A07.0 Balantidiasis	0.000	0.977	0.023
I20.1 Angina pectoris with documented spasm	0.023	0.977	0.000
I25.4 Coronary artery aneurysm	0.023	0.977	0.000
I72.3 Aneurysm of iliac artery	0.022	0.977	0.000
A08.3 Other viral enteritis	0.000	0.977	0.023
I25.3 Aneurysm of heart	0.022	0.977	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.022	0.978	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.022	0.978	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.022	0.978	0.000
I23.8 Other current complications following acute myocardial infarction	0.021	0.978	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.022	0.978	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.022	0.978	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.021	0.978	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.021	0.979	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.021	0.979	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.021	0.979	0.000
A08.5 Other specified intestinal infections	0.000	0.979	0.021
A08.2 Adenoviral enteritis	0.000	0.979	0.021
A08.0 Rotaviral enteritis	0.000	0.979	0.021
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.979	0.021
I28 Other diseases of pulmonary vessels	0.020	0.980	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.020	0.980	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.020	0.980	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.020	0.980	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.019	0.981	0.000
I05-I09 Chronic rheumatic heart diseases	0.018	0.982	0.000
I61 Intracerebral haemorrhage	0.018	0.982	0.000
I78 Diseases of capillaries	0.018	0.982	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.018	0.982	0.000
I73.0 Raynaud's syndrome	0.017	0.983	0.000
I60.8 Other subarachnoid haemorrhage	0.016	0.983	0.000
I71 Aortic aneurysm and dissection	0.016	0.983	0.000
A07.1 Giardiasis [lambliasis]	0.001	0.984	0.016
I26 Pulmonary embolism	0.016	0.984	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.016	0.984	0.000
I25.5 Ischaemic cardiomyopathy	0.016	0.984	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.016	0.984	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.984	0.016
I95 Hypotension	0.016	0.984	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.000	0.984	0.016
I61.5 Intracerebral haemorrhage, intraventricular	0.015	0.985	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.014	0.985	0.000
I28.1 Aneurysm of pulmonary artery	0.014	0.985	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.014	0.985	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.014	0.985	0.000
I73.9 Peripheral vascular disease, unspecified	0.014	0.986	0.000
I95.2 Hypotension due to drugs	0.014	0.986	0.000
I28.8 Other specified diseases of pulmonary vessels	0.014	0.986	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.014	0.986	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.014	0.986	0.000
I06 Rheumatic aortic valve diseases	0.014	0.986	0.000
I78.8 Other diseases of capillaries	0.013	0.986	0.000
I78.9 Disease of capillaries, unspecified	0.013	0.987	0.000
I95.0 Idiopathic hypotension	0.013	0.987	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.013	0.987	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.013	0.987	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.012	0.988	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.012	0.988	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.012	0.988	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.012	0.988	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.012	0.988	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.012	0.988	0.000
A49 Bacterial infection of unspecified site	0.000	0.988	0.012
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.012	0.988	0.000
I74.5 Embolism and thrombosis of iliac artery	0.011	0.988	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.011	0.988	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.011	0.988	0.000
I98.0 Cardiovascular syphilis	0.011	0.988	0.000
I61.8 Other intracerebral haemorrhage	0.011	0.989	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.011	0.989	0.000
I09 Other rheumatic heart diseases	0.011	0.989	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.011	0.989	0.000
N60.8 Other benign mammary dysplasias	0.011	0.989	0.000
I95.1 Orthostatic hypotension	0.011	0.989	0.000
I05 Rheumatic mitral valve diseases	0.010	0.989	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.010	0.990	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.010	0.990	0.000
I97.0 Postcardiotomy syndrome	0.010	0.990	0.000
I05.1 Rheumatic mitral insufficiency	0.010	0.990	0.000
I95.8 Other hypotension	0.010	0.990	0.000
I06.8 Other rheumatic aortic valve diseases	0.010	0.990	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.010	0.990	0.000
I06.1 Rheumatic aortic insufficiency	0.010	0.990	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.010	0.990	0.000
I20.0 Unstable angina	0.010	0.990	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.009	0.990	0.000
I07 Rheumatic tricuspid valve diseases	0.009	0.991	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.009	0.991	0.000
I27 Other pulmonary heart diseases	0.009	0.991	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.000	0.991	0.009
I99 Other and unspecified disorders of circulatory system	0.009	0.991	0.000
I06.0 Rheumatic aortic stenosis	0.009	0.991	0.000
I97.1 Other functional disturbances following cardiac surgery	0.009	0.991	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.009	0.991	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.991	0.009
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.991	0.009
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.991	0.008
I35 Nonrheumatic aortic valve disorders	0.009	0.991	0.000
I30-I52 Other forms of heart disease	0.008	0.992	0.000
A04.5 Campylobacter enteritis	0.001	0.992	0.008
A49.1 Streptococcal infection, unspecified	0.000	0.992	0.008
Chapter I Certain infectious and parasitic diseases	0.000	0.992	0.008
I09.8 Other specified rheumatic heart diseases	0.008	0.992	0.000
I09.2 Chronic rheumatic pericarditis	0.008	0.992	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.008	0.992	0.000
I09.0 Rheumatic myocarditis	0.008	0.992	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.008	0.992	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.992	0.008
E83.1 Disorders of iron metabolism	0.008	0.992	0.000
I05.8 Other mitral valve diseases	0.008	0.992	0.000
I71.0 Dissection of aorta [any part]	0.008	0.992	0.000
B25-B34 Other viral diseases	0.000	0.992	0.008
I08 Multiple valve diseases	0.008	0.992	0.000
I37 Pulmonary valve disorders	0.008	0.992	0.000
A49.9 Bacterial infection, unspecified	0.000	0.992	0.008
B25.9 Cytomegaloviral disease, unspecified	0.000	0.992	0.008
B25 Cytomegaloviral disease	0.000	0.992	0.008
I51 Complications and ill-defined descriptions of heart disease	0.008	0.992	0.000
I51.9 Heart disease, unspecified	0.008	0.992	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.007	0.993	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.007	0.993	0.000
A80-A89 Viral infections of the central nervous system	0.000	0.993	0.007
E83.5 Disorders of calcium metabolism	0.007	0.993	0.000
I07.9 Tricuspid valve disease, unspecified	0.007	0.993	0.000
I07.8 Other tricuspid valve diseases	0.007	0.993	0.000
I07.2 Tricuspid stenosis with insufficiency	0.007	0.993	0.000
I07.0 Tricuspid stenosis	0.007	0.993	0.000
I34 Nonrheumatic mitral valve disorders	0.007	0.993	0.000
I27.1 Kyphoscoliotic heart disease	0.007	0.993	0.000
I51.0 Cardiac septal defect, acquired	0.007	0.993	0.000
I34.0 Mitral (valve) insufficiency	0.007	0.993	0.000
I42 Cardiomyopathy	0.007	0.993	0.000
I37.1 Pulmonary valve insufficiency	0.007	0.993	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.006	0.993	0.001
A86 Unspecified viral encephalitis	0.000	0.993	0.007
I05.2 Mitral stenosis with insufficiency	0.006	0.993	0.000
B15-B19 Viral hepatitis	0.000	0.993	0.007
I27.8 Other specified pulmonary heart diseases	0.007	0.993	0.000
A65-A69 Other spirochaetal diseases	0.000	0.993	0.006
B27 Infectious mononucleosis	0.000	0.993	0.006
I08.9 Multiple valve disease, unspecified	0.006	0.993	0.000
B99-B99 Other infectious diseases	0.000	0.993	0.006
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.000	0.994	0.006
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.000	0.994	0.006
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.000	0.994	0.006
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.000	0.994	0.006
I37.0 Pulmonary valve stenosis	0.006	0.994	0.000
B50-B64 Protozoal diseases	0.000	0.994	0.006
I52 Other heart disorders in diseases classified elsewhere	0.006	0.994	0.000
I48 Atrial fibrillation and flutter	0.006	0.994	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.006	0.994	0.000
I41 Myocarditis in diseases classified elsewhere	0.006	0.994	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I32 Pericarditis in diseases classified elsewhere	0.006	0.994	0.000
E83 Disorders of mineral metabolism	0.006	0.994	0.000
I51.7 Cardiomegaly	0.006	0.994	0.000
I51.4 Myocarditis, unspecified	0.006	0.994	0.000
I21 Acute myocardial infarction	0.006	0.994	0.000
I40 Acute myocarditis	0.006	0.994	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.000	0.994	0.006
A75-A79 Rickettsioses	0.000	0.994	0.006
A70-A74 Other diseases caused by chlamydiae	0.000	0.994	0.006
A20-A28 Certain zoonotic bacterial diseases	0.000	0.994	0.006
D09.0 Bladder	0.000	0.994	0.006
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.006	0.994	0.000
I42.4 Endocardial fibroelastosis	0.006	0.994	0.000
I08.0 Disorders of both mitral and aortic valves	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
I46 Cardiac arrest	0.006	0.994	0.000
B17 Other acute viral hepatitis	0.000	0.994	0.006
I33 Acute and subacute endocarditis	0.006	0.994	0.000
I09.9 Rheumatic heart disease, unspecified	0.006	0.994	0.001
I38 Endocarditis, valve unspecified	0.006	0.994	0.000
I35.1 Aortic (valve) insufficiency	0.006	0.994	0.000
I27.9 Pulmonary heart disease, unspecified	0.006	0.994	0.000
I35.9 Aortic valve disorder, unspecified	0.006	0.994	0.000
Q43.8 Other specified congenital malformations of intestine	0.006	0.994	0.000
I67 Other cerebrovascular diseases	0.006	0.994	0.000
A30-A49 Other bacterial diseases	0.000	0.994	0.006
B33 Other viral diseases, not elsewhere classified	0.000	0.994	0.006
B30 Viral conjunctivitis	0.000	0.994	0.006
B26 Mumps	0.000	0.994	0.006
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.994	0.006
I37.9 Pulmonary valve disorder, unspecified	0.006	0.994	0.000
I37.8 Other pulmonary valve disorders	0.006	0.994	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
B17.1 Acute hepatitis C	0.000	0.994	0.006
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.994	0.006
B25.8 Other cytomegaloviral diseases	0.000	0.994	0.006
B25.2 Cytomegaloviral pancreatitis	0.000	0.994	0.006
B25.1 Cytomegaloviral hepatitis	0.000	0.994	0.006
B25.0 Cytomegaloviral pneumonitis	0.000	0.994	0.006
I51.5 Myocardial degeneration	0.006	0.994	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.006	0.994	0.000
B59 Pneumocystosis	0.000	0.994	0.006
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.006	0.994	0.000
B27.9 Infectious mononucleosis, unspecified	0.000	0.994	0.006
I46.1 Sudden cardiac death, so described	0.006	0.994	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.005	0.994	0.000
I31 Other diseases of pericardium	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.005	0.994	0.000
Q43 Other congenital malformations of intestine	0.005	0.995	0.000
A88 Other viral infections of central nervous system, not elsewhere classified	0.000	0.995	0.005
A85 Other viral encephalitis, not elsewhere classified	0.000	0.995	0.005
A84 Tick-borne viral encephalitis	0.000	0.995	0.005
A83 Mosquito-borne viral encephalitis	0.000	0.995	0.005
A82 Rabies	0.000	0.995	0.005
A81 Atypical virus infections of central nervous system	0.000	0.995	0.005
A80 Acute poliomyelitis	0.000	0.995	0.005
A91 Dengue haemorrhagic fever	0.000	0.995	0.005
A90 Dengue fever [classical dengue]	0.000	0.995	0.005
A89 Unspecified viral infection of central nervous system	0.000	0.995	0.005
B85-B89 Pediculosis, acariasis and other infestations	0.000	0.995	0.005
A15-A19 Tuberculosis	0.000	0.995	0.005
B16 Acute hepatitis B	0.000	0.995	0.005
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
F32.1 Moderate depressive episode	0.000	0.995	0.005
I34.2 Nonrheumatic mitral (valve) stenosis	0.005	0.995	0.000
I69 Sequelae of cerebrovascular disease	0.005	0.995	0.000
A69 Other spirochaetal infections	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.005	0.995	0.000
I27.2 Other secondary pulmonary hypertension	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.005	0.995	0.000
B99 Other and unspecified infectious diseases	0.000	0.995	0.005
I42.7 Cardiomyopathy due to drugs and other external agents	0.005	0.995	0.000
I42.5 Other restrictive cardiomyopathy	0.005	0.995	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.005	0.995	0.000
I42.6 Alcoholic cardiomyopathy	0.005	0.995	0.000
B18 Chronic viral hepatitis	0.000	0.995	0.005
Z92.2 Personal history of long-term (current) use of other medicaments	0.005	0.995	0.000
B65-B83 Helminthiases	0.000	0.995	0.005
Q24 Other congenital malformations of heart	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
B27.8 Other infectious mononucleosis	0.000	0.995	0.005
B27.1 Cytomegaloviral mononucleosis	0.000	0.995	0.005
B27.0 Gammaherpesviral mononucleosis	0.000	0.995	0.005
A68 Relapsing fevers	0.000	0.995	0.005
A67 Pinta [carate]	0.000	0.995	0.005
A66 Yaws	0.000	0.995	0.005
A65 Non-venereal syphilis	0.000	0.995	0.005
I36 Nonrheumatic tricuspid valve disorders	0.005	0.995	0.000
B20.9 HIV disease resulting in unspecified infectious or parasitic disease	0.000	0.995	0.005
B20.8 HIV disease resulting in other infectious and parasitic diseases	0.000	0.995	0.005
B20.7 HIV disease resulting in multiple infections	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations