TreeWAS – Variant ID: rs17412531

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
I10-I15 Hypertensive diseases	0.993	0.007
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
I10 Essential (primary) hypertension	0.988	0.012
I51 Complications and ill-defined descriptions of heart disease	0.987	0.013
M70-M79 Other soft tissue disorders	0.983	0.017
Chapter VIII Diseases of the ear and mastoid process	0.983	0.017
M50-M54 Other dorsopathies	0.983	0.017
Chapter II Neoplasms	0.982	0.018
M72 Fibroblastic disorders	0.982	0.018
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.981	0.019
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.981	0.019
M54 Dorsalgia	0.979	0.021
Chapter IV Endocrine, nutritional and metabolic diseases	0.978	0.022
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.975	0.025
M20-M25 Other joint disorders	0.966	0.034
M54.5 Low back pain	0.961	0.039
C15-C26 Malignant neoplasms of digestive organs	0.960	0.040
M54.9 Dorsalgia, unspecified	0.955	0.045
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.954	0.046
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.953	0.047
E70-E90 Metabolic disorders	0.952	0.048
H90-H95 Other disorders of ear	0.944	0.056
M54.59 Low back pain (Site unspecified)	0.941	0.059
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.941	0.059
M54.99 Dorsalgia, unspecified (Site unspecified)	0.939	0.061
I51.7 Cardiomegaly	0.935	0.065
I49 Other cardiac arrhythmias	0.935	0.065
Chapter XII Diseases of the skin and subcutaneous tissue	0.934	0.066
I35 Nonrheumatic aortic valve disorders	0.930	0.070
I42 Cardiomyopathy	0.924	0.076
C20 Malignant neoplasm of rectum	0.922	0.078
I44 Atrioventricular and left bundle-branch block	0.920	0.080
D37-D48 Neoplasms of uncertain or unknown behaviour	0.918	0.082
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.916	0.084
E87 Other disorders of fluid, electrolyte and acid-base balance	0.908	0.092
H80-H83 Diseases of inner ear	0.908	0.092
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.907	0.093
I38 Endocarditis, valve unspecified	0.902	0.098
S20-S29 Injuries to the thorax	0.899	0.101
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.899	0.101
R06 Abnormalities of breathing	0.895	0.105
M80-M85 Disorders of bone density and structure	0.891	0.109
L80-L99 Other disorders of the skin and subcutaneous tissue	0.888	0.112
R73 Elevated blood glucose level	0.885	0.115
S00-S09 Injuries to the head	0.881	0.119
R06.0 Dyspnoea	0.880	0.120
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.880	0.120
I49.9 Cardiac arrhythmia, unspecified	0.879	0.121
H90 Conductive and sensorineural hearing loss	0.878	0.122
I51.9 Heart disease, unspecified	0.872	0.128
I50 Heart failure	0.869	0.131
E00-E07 Disorders of thyroid gland	0.869	0.131
I42.9 Cardiomyopathy, unspecified	0.869	0.131
H83 Other diseases of inner ear	0.865	0.135
Chapter XX External causes of morbidity and mortality	0.849	0.151
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.847	0.153
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.846	0.154
M20 Acquired deformities of fingers and toes	0.844	0.156
M34 Systemic sclerosis	0.843	0.157
R02 Gangrene, not elsewhere classified	0.842	0.158
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.838	0.161
L89 Decubitus ulcer	0.837	0.163
S10-S19 Injuries to the neck	0.835	0.165
H83.0 Labyrinthitis	0.834	0.166
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.833	0.167
I35.0 Aortic (valve) stenosis	0.832	0.168
R07 Pain in throat and chest	0.828	0.172
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.827	0.173
I35.2 Aortic (valve) stenosis with insufficiency	0.824	0.176
D45 Polycythaemia vera	0.822	0.178
L97 Ulcer of lower limb, not elsewhere classified	0.822	0.178
M05-M14 Inflammatory polyarthropathies	0.821	0.179
H91 Other hearing loss	0.820	0.180
S01 Open wound of head	0.819	0.181
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.818	0.182
I31 Other diseases of pericardium	0.816	0.184
M20.4 Other hammer toe(s) (acquired)	0.815	0.185
E80 Disorders of porphyrin and bilirubin metabolism	0.813	0.187
R50-R69 General symptoms and signs	0.811	0.189
E20-E35 Disorders of other endocrine glands	0.808	0.192
I44.0 Atrioventricular block, first degree	0.808	0.192
C85.1 B-cell lymphoma, unspecified	0.806	0.194
R73.0 Abnormal glucose tolerance test	0.804	0.196
D00-D09 In situ neoplasms	0.803	0.197
C21 Malignant neoplasm of anus and anal canal	0.802	0.198
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.800	0.200
Chapter XXII Codes for special purposes	0.800	0.200
R07.3 Other chest pain	0.800	0.200
R03 Abnormal blood-pressure reading, without diagnosis	0.799	0.201
R79 Other abnormal findings of blood chemistry	0.798	0.202
S60-S69 Injuries to the wrist and hand	0.796	0.204
M31 Other necrotising vasculopathies	0.795	0.205
M30 Polyarteritis nodosa and related conditions	0.793	0.207
H90.2 Conductive hearing loss, unspecified	0.792	0.208
I33 Acute and subacute endocarditis	0.792	0.208
M91-M94 Chondropathies	0.791	0.209
M25 Other joint disorders, not elsewhere classified	0.790	0.210
S90-S99 Injuries to the ankle and foot	0.789	0.211
M86-M90 Other osteopathies	0.788	0.212
E87.7 Fluid overload	0.788	0.212
E87.6 Hypokalaemia	0.788	0.212
M84 Disorders of continuity of bone	0.784	0.216
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.781	0.218
C81 Hodgkin's disease	0.781	0.219
M54.3 Sciatica	0.781	0.219
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.781	0.219
R63 Symptoms and signs concerning food and fluid intake	0.780	0.220
I15 Secondary hypertension	0.779	0.221
L00-L08 Infections of the skin and subcutaneous tissue	0.778	0.222
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.777	0.223
I45 Other conduction disorders	0.777	0.223
C17 Malignant neoplasm of small intestine	0.776	0.224
T84.0 Mechanical complication of internal joint prosthesis	0.775	0.225
M40-M43 Deforming dorsopathies	0.774	0.226
I51.3 Intracardiac thrombosis, not elsewhere classified	0.771	0.229
T15-T19 Effects of foreign body entering through natural orifice	0.771	0.229
Q20-Q28 Congenital malformations of the circulatory system	0.770	0.230
L89.9 Decubitus ulcer and pressure area, unspecified	0.769	0.231
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.768	0.232
M60-M63 Disorders of muscles	0.767	0.232
L50-L54 Urticaria and erythema	0.767	0.233
R72 Abnormality of white blood cells, not elsewhere classified	0.767	0.233
E87.2 Acidosis	0.767	0.233
R77 Other abnormalities of plasma proteins	0.766	0.234
I44.3 Other and unspecified atrioventricular block	0.766	0.234
Chapter XV Pregnancy, childbirth and the puerperium	0.765	0.235
E04 Other non-toxic goitre	0.764	0.236
E74 Other disorders of carbohydrate metabolism	0.764	0.236
I35.1 Aortic (valve) insufficiency	0.761	0.239
S09 Other and unspecified injuries of head	0.761	0.239
I49.5 Sick sinus syndrome	0.760	0.240
I50.1 Left ventricular failure	0.759	0.241
M54.57 Low back pain (Lumbosacral region)	0.758	0.242
R63.8 Other symptoms and signs concerning food and fluid intake	0.758	0.242
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.758	0.242
R01 Cardiac murmurs and other cardiac sounds	0.754	0.246
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.754	0.246
R60 Oedema, not elsewhere classified	0.753	0.247
E88 Other metabolic disorders	0.753	0.247
M06 Other rheumatoid arthritis	0.753	0.247
M45-M49 Spondylopathies	0.753	0.247
T79-T79 Certain early complications of trauma	0.753	0.247
M53 Other dorsopathies, not elsewhere classified	0.753	0.247
M32 Systemic lupus erythematosus	0.752	0.248
M22 Disorders of patella	0.750	0.250
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.750	0.250
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.747	0.253
S01.8 Open wound of other parts of head	0.746	0.254
H60-H62 Diseases of external ear	0.746	0.254
C16 Malignant neoplasm of stomach	0.745	0.255
I70-I79 Diseases of arteries, arterioles and capillaries	0.745	0.255
I36 Nonrheumatic tricuspid valve disorders	0.744	0.256
M24 Other specific joint derangements	0.744	0.256
S29 Other and unspecified injuries of thorax	0.744	0.256
R74 Abnormal serum enzyme levels	0.744	0.256
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.744	0.256
I44.1 Atrioventricular block, second degree	0.743	0.257
C19 Malignant neoplasm of rectosigmoid junction	0.743	0.257
S27 Injury of other and unspecified intrathoracic organs	0.742	0.258
L85 Other epidermal thickening	0.739	0.261
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.738	0.262
S22 Fracture of rib(s), sternum and thoracic spine	0.738	0.262
I27 Other pulmonary heart diseases	0.737	0.263
M65-M68 Disorders of synovium and tendon	0.737	0.263
T87 Complications peculiar to reattachment and amputation	0.735	0.265
I50.0 Congestive heart failure	0.734	0.266
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.734	0.266
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.733	0.267
C82.1 Mixed small cleaved and large cell, follicular	0.732	0.268
R73.9 Hyperglycaemia, unspecified	0.732	0.268
S30 Superficial injury of abdomen, lower back and pelvis	0.731	0.269
H91.9 Hearing loss, unspecified	0.731	0.269
M00-M03 Infectious arthropathies	0.729	0.270
M54.50 Low back pain (Multiple sites in spine)	0.729	0.271
I37 Pulmonary valve disorders	0.727	0.273
Y95 Nosocomial condition	0.727	0.273
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.726	0.274
S01.1 Open wound of eyelid and periocular area	0.724	0.276
M25.5 Pain in joint	0.723	0.277
I42.8 Other cardiomyopathies	0.722	0.278
I31.3 Pericardial effusion (noninflammatory)	0.722	0.278
I51.8 Other ill-defined heart diseases	0.722	0.278
C23 Malignant neoplasm of gallbladder	0.721	0.279
I46 Cardiac arrest	0.721	0.279
I42.6 Alcoholic cardiomyopathy	0.721	0.279
E05 Thyrotoxicosis [hyperthyroidism]	0.721	0.279
I51.4 Myocarditis, unspecified	0.720	0.280
Q80-Q89 Other congenital malformations	0.720	0.280
C51-C58 Malignant neoplasms of female genital organs	0.720	0.280
C25 Malignant neoplasm of pancreas	0.719	0.280
S70-S79 Injuries to the hip and thigh	0.719	0.281
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
H92 Otalgia and effusion of ear	0.716	0.284
X60-X84 Intentional self-harm	0.716	0.284
Y60-Y69 Misadventures to patients during surgical and medical care	0.715	0.285
C64-C68 Malignant neoplasms of urinary tract	0.715	0.285
L89.1 Stage II decubitus ulcer	0.715	0.285
S68 Traumatic amputation of wrist and hand	0.714	0.286
E80.4 Gilbert's syndrome	0.713	0.287
R06.6 Hiccough	0.712	0.288
I13 Hypertensive heart and renal disease	0.712	0.288
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
I51.6 Cardiovascular disease, unspecified	0.708	0.292
I51.5 Myocardial degeneration	0.708	0.292
I51.2 Rupture of papillary muscle, not elsewhere classified	0.708	0.292
I51.0 Cardiac septal defect, acquired	0.708	0.292
M06.9 Rheumatoid arthritis, unspecified	0.705	0.295
M76 Enthesopathies of lower limb, excluding foot	0.705	0.295
M73 Soft tissue disorders in diseases classified elsewhere	0.705	0.295
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.704	0.296
C40-C41 Malignant neoplasms of bone and articular cartilage	0.704	0.296
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.704	0.296
M72.9 Fibroblastic disorder, unspecified	0.704	0.296
M72.8 Other fibroblastic disorders	0.704	0.296
M72.6 Necrotizing fasciitis	0.704	0.296
M72.5 Fasciitis, not elsewhere classified	0.704	0.296
M72.4 Pseudosarcomatous fibromatosis	0.704	0.296
M72.3 Nodular fasciitis	0.704	0.296
M72.1 Knuckle pads	0.704	0.296
E87.1 Hypo-osmolality and hyponatraemia	0.704	0.296
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.703	0.297
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.703	0.297
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.703	0.297
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.703	0.297
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.703	0.297
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.703	0.297
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.703	0.297
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.703	0.297
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.703	0.297
R09.1 Pleurisy	0.703	0.297
I11 Hypertensive heart disease	0.703	0.297
R07.1 Chest pain on breathing	0.702	0.298
M54.8 Other dorsalgia	0.702	0.298
M54.0 Panniculitis affecting regions of neck and back	0.702	0.298
T84.2 Mechanical complication of internal fixation device of other bones	0.702	0.298
D46 Myelodysplastic syndromes	0.702	0.298
R61 Hyperhidrosis	0.700	0.300
E10-E14 Diabetes mellitus	0.700	0.300
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.699	0.300
R95-R99 Ill-defined and unknown causes of mortality	0.699	0.301
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.699	0.301
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.697	0.303
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.697	0.303
I49.4 Other and unspecified premature depolarisation	0.696	0.304
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.694	0.305
M84.1 Nonunion of fracture [pseudarthrosis]	0.694	0.306
I49.0 Ventricular fibrillation and flutter	0.694	0.306
M72.2 Plantar fascial fibromatosis	0.694	0.306
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.692	0.307
M33 Dermatopolymyositis	0.692	0.307
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.692	0.308
I44.7 Left bundle-branch block, unspecified	0.692	0.308
M25.57 Pain in joint (Ankle and foot)	0.691	0.309
I42.0 Dilated cardiomyopathy	0.691	0.309
M77 Other enthesopathies	0.690	0.310
M34.9 Systemic sclerosis, unspecified	0.690	0.310
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.690	0.310
E87.5 Hyperkalaemia	0.689	0.311
M54.55 Low back pain (Thoracolumbar region)	0.689	0.311
M54.54 Low back pain-Thoracic	0.689	0.311
M54.53 Low back pain-Cervicothoracic	0.689	0.311
M54.52 Low back pain-Cervical	0.689	0.311
M54.51 Low back pain-Occipit-atl-axl	0.689	0.311
M54.36 Sciatica (Lumbar region)	0.689	0.311
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.689	0.311
C88 Malignant immunoproliferative diseases	0.688	0.312
C26 Malignant neoplasm of other and ill-defined digestive organs	0.688	0.312
C80 Malignant neoplasm without specification of site	0.687	0.313
I12 Hypertensive renal disease	0.685	0.315
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.685	0.315
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.685	0.315
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.685	0.315
M54.94 Dorsalgia, unspecified (Thoracic region)	0.685	0.315
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.685	0.315
M54.92 Dorsalgia, unspecified (Cervical region)	0.685	0.315
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.685	0.315
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.685	0.315
R78 Findings of drugs and other substances, not normally found in blood	0.684	0.316
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.684	0.316
R71 Abnormality of red blood cells	0.684	0.316
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.683	0.316
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.683	0.317
E85 Amyloidosis	0.682	0.318
E84 Cystic fibrosis	0.682	0.318
E79 Disorders of purine and pyrimidine metabolism	0.682	0.318
E77 Disorders of glycoprotein metabolism	0.682	0.318
E76 Disorders of glycosaminoglycan metabolism	0.682	0.318
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.682	0.318
E73 Lactose intolerance	0.682	0.318
E72 Other disorders of amino-acid metabolism	0.682	0.318
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.682	0.318
E70 Disorders of aromatic amino-acid metabolism	0.682	0.318
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.682	0.318
L91 Hypertrophic disorders of skin	0.682	0.318
M82 Osteoporosis in diseases classified elsewhere	0.681	0.319
C21.0 Anus, unspecified	0.681	0.319
E29 Testicular dysfunction	0.681	0.319
H90.3 Sensorineural hearing loss, bilateral	0.680	0.320
I49.8 Other specified cardiac arrhythmias	0.680	0.320
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.679	0.321
T88 Other complications of surgical and medical care, not elsewhere classified	0.678	0.322
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.678	0.322
T36-T50 Poisoning by drugs, medicaments and biological substances	0.678	0.322
I34 Nonrheumatic mitral valve disorders	0.678	0.322
R94 Abnormal results of function studies	0.677	0.323
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.677	0.323
H94 Other disorders of ear in diseases classified elsewhere	0.677	0.323
E40-E46 Malnutrition	0.677	0.323
I05-I09 Chronic rheumatic heart diseases	0.676	0.324
E24 Cushing's syndrome	0.676	0.324
L03 Cellulitis	0.676	0.324
S09.9 Unspecified injury of head	0.675	0.324
R59 Enlarged lymph nodes	0.675	0.325
I45.1 Other and unspecified right bundle-branch block	0.675	0.325
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.675	0.325
C95 Leukaemia of unspecified cell type	0.675	0.325
C94 Other leukaemias of specified cell type	0.675	0.325
C93 Monocytic leukaemia	0.675	0.325
C86 Other specified types of T/NK-cell lymphoma	0.675	0.325
C84 Peripheral and cutaneous T-cell lymphomas	0.675	0.325
R60.0 Localised oedema	0.674	0.326
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.672	0.328
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.671	0.329
M34.8 Other forms of systemic sclerosis	0.670	0.330
L60-L75 Disorders of skin appendages	0.670	0.330
I49.2 Junctional premature depolarisation	0.670	0.330
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.670	0.330
L94 Other localised connective tissue disorders	0.670	0.330
L10-L14 Bullous disorders	0.670	0.330
M81 Osteoporosis without pathological fracture	0.670	0.330
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.669	0.331
Q50-Q56 Congenital malformations of genital organs	0.669	0.331
R09.0 Asphyxia	0.668	0.332
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.668	0.332
T80 Complications following infusion, transfusion and therapeutic injection	0.668	0.332
H93 Other disorders of ear, not elsewhere classified	0.668	0.332
H81 Disorders of vestibular function	0.668	0.332
M71 Other bursopathies	0.667	0.333
S36 Injury of intra-abdominal organs	0.666	0.334
M70 Soft tissue disorders related to use, overuse and pressure	0.665	0.335
M20.1 Hallux valgus (acquired)	0.665	0.335
M25.51 Pain in joint (Shoulder region)	0.664	0.336
E04.2 Non-toxic multinodular goitre	0.664	0.336
S69 Other and unspecified injuries of wrist and hand	0.664	0.336
L83 Acanthosis nigricans	0.663	0.337
I42.7 Cardiomyopathy due to drugs and other external agents	0.662	0.337
I42.5 Other restrictive cardiomyopathy	0.662	0.337
I42.4 Endocardial fibroelastosis	0.662	0.337
I42.3 Endomyocardial (eosinophilic) disease	0.662	0.337
M54.96 Dorsalgia, unspecified (Lumbar region)	0.662	0.338
R58 Haemorrhage, not elsewhere classified	0.662	0.338
S05 Injury of eye and orbit	0.661	0.338
S19 Other and unspecified injuries of neck	0.661	0.339
T90 Sequelae of injuries of head	0.660	0.340
I44.6 Other and unspecified fascicular block	0.659	0.341
I44.5 Left posterior fascicular block	0.659	0.341
I44.4 Left anterior fascicular block	0.659	0.341
V10-V19 Pedal cyclist injured in transport accident	0.659	0.341
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.659	0.341
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.658	0.342
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.658	0.342
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.658	0.342
M85 Other disorders of bone density and structure	0.657	0.343
M94 Other disorders of cartilage	0.657	0.343
R76 Other abnormal immunological findings in serum	0.657	0.343
M45 Ankylosing spondylitis	0.656	0.344
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.655	0.345
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.655	0.345
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.655	0.345
M34.1 CR(E)ST syndrome	0.654	0.346
L85.9 Epidermal thickening, unspecified	0.653	0.347
R57 Shock, not elsewhere classified	0.653	0.347
E87.4 Mixed disorder of acid-base balance	0.651	0.349
S01.2 Open wound of nose	0.651	0.349
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.651	0.349
H82 Vertiginous syndromes in diseases classified elsewhere	0.651	0.349
C85.7 Other specified types of non-Hodgkin's lymphoma	0.651	0.349
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.651	0.349
C85.0 Lymphosarcoma	0.651	0.349
H90.5 Sensorineural hearing loss, unspecified	0.650	0.350
X58-X59 Accidental exposure to other and unspecified factors	0.649	0.351
L02 Cutaneous abscess, furuncle and carbuncle	0.649	0.351
Q23 Congenital malformations of aortic and mitral valves	0.648	0.352
L95 Vasculitis limited to skin, not elsewhere classified	0.647	0.353
L82 Seborrhoeic keratosis	0.646	0.354
M54.2 Cervicalgia	0.646	0.354
E06 Thyroiditis	0.646	0.354
M54.6 Pain in thoracic spine	0.645	0.354
M22.2 Patellofemoral disorders	0.646	0.354
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.645	0.355
Q35-Q37 Cleft lip and cleft palate	0.645	0.355
Q30-Q34 Congenital malformations of the respiratory system	0.645	0.355
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.645	0.355
S26 Injury of heart	0.645	0.355
S25 Injury of blood vessels of thorax	0.645	0.355
S24 Injury of nerves and spinal cord at thorax level	0.645	0.355
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.645	0.355
S21 Open wound of thorax	0.645	0.355
O00-O08 Pregnancy with abortive outcome	0.645	0.355
M54.1 Radiculopathy	0.643	0.356
I33.0 Acute and subacute infective endocarditis	0.643	0.357
R06.7 Sneezing	0.642	0.358
R06.3 Periodic breathing	0.642	0.358
R06.1 Stridor	0.642	0.358
D05 Carcinoma in situ of breast	0.642	0.358
V20-V29 Motorcycle rider injured in transport accident	0.641	0.359
V40-V49 Car occupant injured in transport accident	0.641	0.359
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.641	0.359
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.641	0.359
T86 Failure and rejection of transplanted organs and tissues	0.641	0.359
E83 Disorders of mineral metabolism	0.640	0.360
S01.5 Open wound of lip and oral cavity	0.640	0.360
I30 Acute pericarditis	0.639	0.361
M83 Adult osteomalacia	0.638	0.361
S90 Superficial injury of ankle and foot	0.638	0.362
C81.9 Hodgkin's disease, unspecified	0.638	0.362
M21 Other acquired deformities of limbs	0.638	0.362
E87.0 Hyperosmolality and hypernatraemia	0.638	0.362
Q38-Q45 Other congenital malformations of the digestive system	0.638	0.362
C18 Malignant neoplasm of colon	0.637	0.363
M31.6 Other giant cell arteritis	0.637	0.363
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.637	0.363
L93 Lupus erythematosus	0.637	0.363
L87 Transepidermal elimination disorders	0.637	0.363
L88 Pyoderma gangrenosum	0.637	0.363
L86 Keratoderma in diseases classified elsewhere	0.637	0.363
L80 Vitiligo	0.637	0.363
I71 Aortic aneurysm and dissection	0.637	0.363
M25.6 Stiffness of joint, not elsewhere classified	0.636	0.363
M20.5 Other deformities of toe(s) (acquired)	0.636	0.364
E87.3 Alkalosis	0.635	0.365
E07 Other disorders of thyroid	0.633	0.366
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.633	0.367
S29.9 Unspecified injury of thorax	0.633	0.367
I95-I99 Other and unspecified disorders of the circulatory system	0.633	0.367
R77.9 Abnormality of plasma protein, unspecified	0.632	0.368
R79.8 Other specified abnormal findings of blood chemistry	0.631	0.369
S08 Traumatic amputation of part of head	0.631	0.369
S07 Crushing injury of head	0.631	0.369
S04 Injury of cranial nerves	0.631	0.369
S03 Dislocation, sprain and strain of joints and ligaments of head	0.631	0.369
R21 Rash and other nonspecific skin eruption	0.631	0.369
R52 Pain, not elsewhere classified	0.630	0.370
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.629	0.370
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.629	0.370
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.629	0.370
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.629	0.370
H90.0 Conductive hearing loss, bilateral	0.629	0.370
E74.3 Other disorders of intestinal carbohydrate absorption	0.629	0.371
T81 Complications of procedures, not elsewhere classified	0.629	0.371
R93 Abnormal findings on diagnostic imaging of other body structures	0.628	0.372
S67 Crushing injury of wrist and hand	0.626	0.374
I15.1 Hypertension secondary to other renal disorders	0.626	0.374
S30.1 Contusion of abdominal wall	0.626	0.374
Q24 Other congenital malformations of heart	0.626	0.374
M35 Other systemic involvement of connective tissue	0.624	0.376
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.623	0.377
E00 Congenital iodine-deficiency syndrome	0.623	0.377
E02 Subclinical iodine-deficiency hypothyroidism	0.623	0.377
W20-W49 Exposure to inanimate mechanical forces	0.623	0.377
C56 Malignant neoplasm of ovary	0.622	0.378
M31.3 Wegener's granulomatosis	0.622	0.378
D07 Carcinoma in situ of other and unspecified genital organs	0.622	0.378
S06 Intracranial injury	0.622	0.378
S20 Superficial injury of thorax	0.621	0.379
R61.9 Hyperhidrosis, unspecified	0.621	0.379
M54.56 Low back pain (Lumbar region)	0.621	0.379
D47.2 Monoclonal gammopathy	0.620	0.379
H83.9 Disease of inner ear, unspecified	0.620	0.380
H83.8 Other specified diseases of inner ear	0.620	0.380
H83.3 Noise effects on inner ear	0.620	0.380
H83.2 Labyrinthine dysfunction	0.620	0.380
H83.1 Labyrinthine fistula	0.620	0.380
L91.0 Keloid scar	0.620	0.380
L40-L45 Papulosquamous disorders	0.619	0.381
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.619	0.381
R60.1 Generalised oedema	0.619	0.381
R79.9 Abnormal finding of blood chemistry, unspecified	0.618	0.382
I27.0 Primary pulmonary hypertension	0.617	0.383
D37.4 Colon	0.617	0.383
R09.2 Respiratory arrest	0.617	0.383
M41 Scoliosis	0.616	0.384
R01.1 Cardiac murmur, unspecified	0.616	0.384

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations