TreeWAS – Variant ID: rs17477177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.973	0.027	0.000
I10-I15 Hypertensive diseases	0.803	0.197	0.000
I12 Hypertensive renal disease	0.776	0.224	0.000
I12.0 Hypertensive renal disease with renal failure	0.766	0.234	0.000
I13 Hypertensive heart and renal disease	0.575	0.424	0.000
I11 Hypertensive heart disease	0.560	0.440	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.414	0.586	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.413	0.587	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.413	0.587	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.413	0.587	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.413	0.587	0.000
I12.9 Hypertensive renal disease without renal failure	0.399	0.601	0.000
I15 Secondary hypertension	0.371	0.628	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.371	0.629	0.000
I65.2 Occlusion and stenosis of carotid artery	0.355	0.645	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.675	0.325
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.311	0.689	0.000
Chapter IX Diseases of the circulatory system	0.292	0.708	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.280	0.720	0.000
I77 Other disorders of arteries and arterioles	0.277	0.723	0.000
I60-I69 Cerebrovascular diseases	0.275	0.725	0.000
I15.8 Other secondary hypertension	0.266	0.733	0.001
I15.2 Hypertension secondary to endocrine disorders	0.266	0.733	0.001
I15.0 Renovascular hypertension	0.266	0.733	0.001
I70 Atherosclerosis	0.266	0.734	0.000
I77.8 Other specified disorders of arteries and arterioles	0.252	0.748	0.000
I77.1 Stricture of artery	0.251	0.749	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.246	0.754	0.000
I24.8 Other forms of acute ischaemic heart disease	0.241	0.759	0.000
I20-I25 Ischaemic heart diseases	0.238	0.762	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.234	0.766	0.000
I24 Other acute ischaemic heart diseases	0.233	0.767	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.233	0.767	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.233	0.767	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.229	0.771	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.223	0.777	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.223	0.777	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.223	0.777	0.000
I65.1 Occlusion and stenosis of basilar artery	0.223	0.777	0.000
I00-I02 Acute rheumatic fever	0.222	0.778	0.000
I77.0 Arteriovenous fistula, acquired	0.221	0.779	0.000
I73 Other peripheral vascular diseases	0.219	0.781	0.000
I70.0 Atherosclerosis of aorta	0.217	0.783	0.000
I15.9 Seconday hypertension, unspecified	0.207	0.792	0.001
I25.1 Atherosclerotic heart disease	0.208	0.792	0.000
I77.6 Arteritis, unspecified	0.204	0.796	0.000
I62 Other nontraumatic intracranial haemorrhage	0.203	0.797	0.000
I70.1 Atherosclerosis of renal artery	0.203	0.797	0.000
I72 Other aneurysm	0.202	0.798	0.000
I25 Chronic ischaemic heart disease	0.199	0.801	0.000
I77.5 Necrosis of artery	0.199	0.801	0.000
I77.4 Coeliac artery compression syndrome	0.199	0.801	0.000
I77.3 Arterial fibromuscular dysplasia	0.199	0.801	0.000
I70.8 Atherosclerosis of other arteries	0.194	0.806	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.191	0.809	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.191	0.809	0.000
I70.9 Generalised and unspecified atherosclerosis	0.191	0.809	0.000
I60 Subarachnoid haemorrhage	0.191	0.809	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.188	0.812	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.185	0.814	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.185	0.815	0.000
E86 Volume depletion	0.185	0.815	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.183	0.817	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.182	0.818	0.000
I77.2 Rupture of artery	0.176	0.824	0.000
I72.0 Aneurysm of carotid artery	0.174	0.826	0.000
I15.1 Hypertension secondary to other renal disorders	0.172	0.827	0.001
I00 Rheumatic fever without mention of heart involvement	0.172	0.828	0.000
I74 Arterial embolism and thrombosis	0.171	0.829	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.170	0.830	0.000
I72.8 Aneurysm of other specified arteries	0.169	0.831	0.000
E87.6 Hypokalaemia	0.165	0.835	0.000
I73.8 Other specified peripheral vascular diseases	0.164	0.836	0.000
I95 Hypotension	0.160	0.840	0.000
I02 Rheumatic chorea	0.159	0.840	0.000
I01 Rheumatic fever with heart involvement	0.159	0.840	0.000
E70-E90 Metabolic disorders	0.157	0.843	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.157	0.843	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.156	0.844	0.000
I24.1 Dressler's syndrome	0.156	0.844	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.155	0.844	0.000
I62.1 Nontraumatic extradural haemorrhage	0.154	0.846	0.000
I95.2 Hypotension due to drugs	0.152	0.848	0.000
I73.0 Raynaud's syndrome	0.151	0.849	0.000
I23 Certain current complications following acute myocardial infarction	0.150	0.850	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.149	0.851	0.000
E83 Disorders of mineral metabolism	0.148	0.852	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.146	0.854	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.145	0.854	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.145	0.855	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.145	0.855	0.000
I72.1 Aneurysm of artery of upper extremity	0.145	0.855	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.145	0.855	0.000
I72.9 Aneurysm of unspecified site	0.144	0.856	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.144	0.856	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.143	0.857	0.000
I25.6 Silent myocardial ischaemia	0.143	0.857	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.142	0.858	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.141	0.859	0.000
I22 Subsequent myocardial infarction	0.140	0.860	0.000
E83.1 Disorders of iron metabolism	0.140	0.860	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.139	0.861	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.139	0.861	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.137	0.863	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.137	0.863	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.137	0.863	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.137	0.863	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.137	0.863	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.137	0.863	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.137	0.863	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.137	0.863	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.137	0.863	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.137	0.863	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.137	0.863	0.000
I25.3 Aneurysm of heart	0.137	0.863	0.000
E83.5 Disorders of calcium metabolism	0.134	0.866	0.000
I95.0 Idiopathic hypotension	0.133	0.867	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.133	0.867	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.133	0.867	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.133	0.867	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.132	0.868	0.000
I20 Angina pectoris	0.132	0.868	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.132	0.868	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.131	0.868	0.000
I79.1 Aortitis in diseases classified elsewhere	0.131	0.868	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.131	0.868	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.131	0.869	0.000
E80.1 Porphyria cutanea tarda	0.129	0.871	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.129	0.871	0.000
E80.6 Other disorders of bilirubin metabolism	0.128	0.872	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.127	0.872	0.000
I72.2 Aneurysm of renal artery	0.127	0.873	0.000
I25.5 Ischaemic cardiomyopathy	0.127	0.873	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.127	0.873	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.126	0.873	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.126	0.874	0.000
I74.8 Embolism and thrombosis of other arteries	0.125	0.875	0.000
A04 Other bacterial intestinal infections	0.000	0.876	0.124
I74.9 Embolism and thrombosis of unspecified artery	0.123	0.877	0.000
E80.4 Gilbert's syndrome	0.122	0.878	0.000
I68.0 Cerebral amyloid angiopathy	0.121	0.879	0.000
I73.9 Peripheral vascular disease, unspecified	0.119	0.881	0.000
I22.8 Subsequent myocardial infarction of other sites	0.119	0.881	0.000
I61 Intracerebral haemorrhage	0.119	0.881	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.119	0.881	0.000
E88 Other metabolic disorders	0.118	0.882	0.000
I95.1 Orthostatic hypotension	0.118	0.882	0.000
I72.4 Aneurysm of artery of lower extremity	0.117	0.882	0.000
I05-I09 Chronic rheumatic heart diseases	0.117	0.883	0.000
E74 Other disorders of carbohydrate metabolism	0.116	0.884	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.115	0.884	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.114	0.885	0.000
I01.8 Other acute rheumatic heart disease	0.114	0.885	0.000
I01.2 Acute rheumatic myocarditis	0.114	0.885	0.000
I01.1 Acute rheumatic endocarditis	0.114	0.885	0.000
I01.0 Acute rheumatic pericarditis	0.114	0.885	0.000
I02.9 Rheumatic chorea without heart involvement	0.114	0.885	0.000
I02.0 Rheumatic chorea with heart involvement	0.114	0.885	0.000
I20.9 Angina pectoris, unspecified	0.114	0.886	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.113	0.886	0.000
E84 Cystic fibrosis	0.113	0.887	0.000
E79 Disorders of purine and pyrimidine metabolism	0.113	0.887	0.000
E77 Disorders of glycoprotein metabolism	0.113	0.887	0.000
E76 Disorders of glycosaminoglycan metabolism	0.113	0.887	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.113	0.887	0.000
E72 Other disorders of amino-acid metabolism	0.113	0.887	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.113	0.887	0.000
E70 Disorders of aromatic amino-acid metabolism	0.113	0.887	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.113	0.887	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.112	0.888	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.111	0.889	0.000
E80.2 Other porphyria	0.108	0.891	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.107	0.892	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.107	0.892	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.107	0.892	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.107	0.892	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.107	0.892	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.107	0.892	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.107	0.892	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.107	0.893	0.000
E80.5 Crigler-Najjar syndrome	0.107	0.893	0.000
E80.3 Defects of catalase and peroxydase	0.107	0.893	0.000
E80.0 Hereditary erythropoietic porphyria	0.107	0.893	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.106	0.894	0.000
E83.8 Other disorders of mineral metabolism	0.106	0.894	0.000
E83.2 Disorders of zinc metabolism	0.106	0.894	0.000
E83.0 Disorders of copper metabolism	0.106	0.894	0.000
I72.3 Aneurysm of iliac artery	0.106	0.894	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.106	0.894	0.000
E87.4 Mixed disorder of acid-base balance	0.103	0.897	0.000
A04.9 Bacterial intestinal infection, unspecified	0.000	0.897	0.103
I60.8 Other subarachnoid haemorrhage	0.102	0.897	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.102	0.898	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.101	0.899	0.000
I25.4 Coronary artery aneurysm	0.100	0.900	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.099	0.900	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.098	0.902	0.000
I97.0 Postcardiotomy syndrome	0.098	0.902	0.000
E83.4 Disorders of magnesium metabolism	0.098	0.902	0.000
E87.7 Fluid overload	0.097	0.903	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.905	0.095
A00-A09 Intestinal infectious diseases	0.000	0.905	0.095
I74.5 Embolism and thrombosis of iliac artery	0.095	0.905	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.095	0.905	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.095	0.905	0.000
I98.0 Cardiovascular syphilis	0.095	0.905	0.000
E88.8 Other specified metabolic disorders	0.093	0.906	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.093	0.907	0.000
E73 Lactose intolerance	0.093	0.907	0.000
I06 Rheumatic aortic valve diseases	0.093	0.907	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.907	0.093
E85 Amyloidosis	0.092	0.907	0.000
I95.8 Other hypotension	0.092	0.908	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.091	0.908	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.090	0.910	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.911	0.089
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.911	0.089
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.911	0.089
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.911	0.089
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.911	0.089
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.089	0.911	0.000
E87.3 Alkalosis	0.089	0.911	0.000
I97.1 Other functional disturbances following cardiac surgery	0.089	0.911	0.000
E87.5 Hyperkalaemia	0.089	0.911	0.000
A04.4 Other intestinal Escherichia coli infections	0.000	0.914	0.086
I23.8 Other current complications following acute myocardial infarction	0.086	0.914	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.086	0.914	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.085	0.914	0.000
E88.2 Lipomatosis, not elsewhere classified	0.085	0.914	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.085	0.915	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.085	0.915	0.000
I61.8 Other intracerebral haemorrhage	0.085	0.915	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.085	0.915	0.000
E88.9 Metabolic disorder, unspecified	0.084	0.915	0.000
E88.3 Tumour lysis syndrome	0.084	0.915	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.084	0.915	0.000
I78 Diseases of capillaries	0.084	0.916	0.001
I20.8 Other forms of angina pectoris	0.084	0.916	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.083	0.917	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.083	0.917	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.083	0.917	0.000
E74.2 Disorders of galactose metabolism	0.083	0.917	0.000
E74.1 Disorders of fructose metabolism	0.083	0.917	0.000
E74.0 Glycogen storage disease	0.083	0.917	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.082	0.918	0.000
I20.1 Angina pectoris with documented spasm	0.082	0.918	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.081	0.919	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.081	0.919	0.000
E70.3 Albinism	0.081	0.919	0.000
E70.2 Disorders of tyrosine metabolism	0.081	0.919	0.000
E70.1 Other hyperphenylalaninaemias	0.081	0.919	0.000
E70.0 Classical phenylketonuria	0.081	0.919	0.000
E71.3 Disorders of fatty-acid metabolism	0.081	0.919	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.081	0.919	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.081	0.919	0.000
E71.0 Maple-syrup-urine disease	0.081	0.919	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.081	0.919	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.081	0.919	0.000
E72.5 Disorders of glycine metabolism	0.081	0.919	0.000
E72.4 Disorders of ornithine metabolism	0.081	0.919	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.081	0.919	0.000
E72.2 Disorders of urea cycle metabolism	0.081	0.919	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.081	0.919	0.000
E72.0 Disorders of amino-acid transport	0.081	0.919	0.000
E75.6 Lipid storage disorder, unspecified	0.081	0.919	0.000
E75.5 Other lipid storage disorders	0.081	0.919	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.081	0.919	0.000
E75.3 Sphingolipidosis, unspecified	0.081	0.919	0.000
E75.2 Other sphingolipidosis	0.081	0.919	0.000
E75.1 Other gangliosidosis	0.081	0.919	0.000
E75.0 GM2 gangliosidosis	0.081	0.919	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.081	0.919	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.081	0.919	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.081	0.919	0.000
E76.2 Other mucopolysaccharidoses	0.081	0.919	0.000
E76.1 Mucopolysaccharidosis, type II	0.081	0.919	0.000
E76.0 Mucopolysaccharidosis, type I	0.081	0.919	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.081	0.919	0.000
E77.8 Other disorders of glycoprotein metabolism	0.081	0.919	0.000
E77.1 Defects in glycoprotein degradation	0.081	0.919	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.081	0.919	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.081	0.919	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.081	0.919	0.000
E79.1 Lesch-Nyhan syndrome	0.081	0.919	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.081	0.919	0.000
E84.9 Cystic fibrosis, unspecified	0.081	0.919	0.000
E84.8 Cystic fibrosis with other manifestations	0.081	0.919	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.081	0.919	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.081	0.919	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.080	0.920	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.079	0.921	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.077	0.923	0.000
I05 Rheumatic mitral valve diseases	0.077	0.923	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.076	0.924	0.000
I09 Other rheumatic heart diseases	0.073	0.926	0.000
E89.2 Postprocedural hypoparathyroidism	0.073	0.927	0.000
E83.3 Disorders of phosphorus metabolism	0.072	0.928	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.071	0.929	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.071	0.929	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.070	0.930	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.069	0.930	0.000
I05.1 Rheumatic mitral insufficiency	0.069	0.931	0.000
I28 Other diseases of pulmonary vessels	0.069	0.931	0.000
A06 Amoebiasis	0.000	0.931	0.068
A05 Other bacterial foodborne intoxications	0.000	0.931	0.068
A03 Shigellosis	0.000	0.931	0.068
A01 Typhoid and paratyphoid fevers	0.000	0.931	0.068
A00 Cholera	0.000	0.931	0.068
E87.0 Hyperosmolality and hypernatraemia	0.068	0.932	0.000
I71 Aortic aneurysm and dissection	0.068	0.932	0.000
E73.8 Other lactose intolerance	0.067	0.933	0.000
E73.1 Secondary lactase deficiency	0.067	0.933	0.000
E73.0 Congenital lactase deficiency	0.067	0.933	0.000
I06.8 Other rheumatic aortic valve diseases	0.067	0.933	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.067	0.933	0.000
I06.1 Rheumatic aortic insufficiency	0.067	0.933	0.000
I06.0 Rheumatic aortic stenosis	0.067	0.933	0.000
A02 Other Salmonella infections	0.000	0.933	0.067
E85.8 Other amyloidosis	0.066	0.933	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.066	0.933	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.066	0.933	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.066	0.933	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.065	0.935	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.065	0.935	0.000
E89.5 Postprocedural testicular hypofunction	0.065	0.935	0.000
E89.1 Postprocedural hypoinsulinaemia	0.065	0.935	0.000
E85.3 Secondary systemic amyloidosis	0.064	0.936	0.000
I78.8 Other diseases of capillaries	0.063	0.936	0.000
E89.4 Postprocedural ovarian failure	0.063	0.937	0.000
E85.9 Amyloidosis, unspecified	0.062	0.937	0.000
I07 Rheumatic tricuspid valve diseases	0.062	0.938	0.000
A08 Viral and other specified intestinal infections	0.000	0.938	0.061
E89.3 Postprocedural hypopituitarism	0.061	0.939	0.000
I78.9 Disease of capillaries, unspecified	0.060	0.939	0.001
A07 Other protozoal intestinal diseases	0.000	0.943	0.057
I05.2 Mitral stenosis with insufficiency	0.056	0.944	0.000
E85.4 Organ-limited amyloidosis	0.055	0.945	0.000
I05.8 Other mitral valve diseases	0.055	0.945	0.000
G93 Other disorders of brain	0.000	0.945	0.055
I08 Multiple valve diseases	0.055	0.945	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.055	0.945	0.000
G93.9 Disorder of brain, unspecified	0.000	0.946	0.054
I09.8 Other specified rheumatic heart diseases	0.053	0.947	0.000
I09.2 Chronic rheumatic pericarditis	0.053	0.947	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.053	0.947	0.000
I09.0 Rheumatic myocarditis	0.053	0.947	0.000
G93.8 Other specified disorders of brain	0.000	0.949	0.051
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.949	0.051
I99 Other and unspecified disorders of circulatory system	0.049	0.950	0.001
I28.9 Disease of pulmonary vessels, unspecified	0.049	0.950	0.000
I28.1 Aneurysm of pulmonary artery	0.049	0.950	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.049	0.950	0.000
A00.9 Cholera, unspecified	0.000	0.951	0.049
A00.1 Cholera due to Vibrio cholerae 01, biovar el tor	0.000	0.951	0.049
A00.0 Cholera due to Vibrio cholerae 01, biovar cholerae	0.000	0.951	0.049
A01.4 Paratyphoid fever, unspecified	0.000	0.951	0.049
A01.3 Paratyphoid fever C	0.000	0.951	0.049
A01.2 Paratyphoid fever B	0.000	0.951	0.049
A01.1 Paratyphoid fever A	0.000	0.951	0.049
A01.0 Typhoid fever	0.000	0.951	0.049
A03.9 Shigellosis, unspecified	0.000	0.951	0.049
A03.8 Other shigellosis	0.000	0.951	0.049
A03.3 Shigellosis due to Shigella sonnei	0.000	0.951	0.049
A03.2 Shigellosis due to Shigella boydii	0.000	0.951	0.049
A03.1 Shigellosis due to Shigella flexneri	0.000	0.951	0.049
A03.0 Shigellosis due to Shigella dysenteriae	0.000	0.951	0.049
A05.9 Bacterial foodborne intoxication, unspecified	0.000	0.951	0.049
A05.8 Other specified bacterial foodborne intoxications	0.000	0.951	0.049
A05.4 Foodborne Bacillus cereus intoxication	0.000	0.951	0.049
A05.3 Foodborne Vibrio parahaemolyticus intoxication	0.000	0.951	0.049
A05.2 Foodborne Clostridium perfringens [Clostridium welchii] intoxication	0.000	0.951	0.049
A05.1 Botulism	0.000	0.951	0.049
A05.0 Foodborne staphylococcal intoxication	0.000	0.951	0.049
A06.9 Amoebiasis, unspecified	0.000	0.951	0.049
A06.8 Amoebic infection of other sites	0.000	0.951	0.049
A06.7 Cutaneous amoebiasis	0.000	0.951	0.049
A06.6 Amoebic brain abscess	0.000	0.951	0.049
A06.5 Amoebic lung abscess	0.000	0.951	0.049
A06.4 Amoebic liver abscess	0.000	0.951	0.049
A06.3 Amoeboma of intestine	0.000	0.951	0.049
A06.2 Amoebic nondysenteric colitis	0.000	0.951	0.049
A06.1 Chronic intestinal amoebiasis	0.000	0.951	0.049
A06.0 Acute amoebic dysentery	0.000	0.951	0.049
G93.4 Encephalopathy, unspecified	0.000	0.951	0.049
I71.3 Abdominal aortic aneurysm, ruptured	0.049	0.951	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.049	0.951	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.049	0.951	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.049	0.951	0.000
G93.0 Cerebral cysts	0.000	0.951	0.049
A02.9 Salmonella infection, unspecified	0.000	0.952	0.048
A02.8 Other specified Salmonella infections	0.000	0.952	0.048
A02.2 Localised Salmonella infections	0.000	0.952	0.048
A02.1 Salmonella septicaemia	0.000	0.952	0.048
E73.9 Lactose intolerance, unspecified	0.047	0.953	0.000
G93.3 Postviral fatigue syndrome	0.000	0.953	0.047
A02.0 Salmonella gastro-enteritis	0.000	0.953	0.046
I28.8 Other specified diseases of pulmonary vessels	0.045	0.955	0.000
I67 Other cerebrovascular diseases	0.045	0.955	0.000
I26 Pulmonary embolism	0.045	0.955	0.000
I07.9 Tricuspid valve disease, unspecified	0.044	0.955	0.000
I07.8 Other tricuspid valve diseases	0.044	0.955	0.000
I07.2 Tricuspid stenosis with insufficiency	0.044	0.955	0.000
I07.0 Tricuspid stenosis	0.044	0.955	0.000
A08.5 Other specified intestinal infections	0.000	0.956	0.044
A08.3 Other viral enteritis	0.000	0.956	0.044
A08.2 Adenoviral enteritis	0.000	0.956	0.044
A08.0 Rotaviral enteritis	0.000	0.956	0.044
I08.9 Multiple valve disease, unspecified	0.042	0.958	0.000
I09.9 Rheumatic heart disease, unspecified	0.042	0.958	0.000
I20.0 Unstable angina	0.042	0.958	0.000
A07.9 Protozoal intestinal disease, unspecified	0.000	0.959	0.041
A07.8 Other specified protozoal intestinal diseases	0.000	0.959	0.041
A07.3 Isosporiasis	0.000	0.959	0.041
A07.2 Cryptosporidiosis	0.000	0.959	0.041
A07.0 Balantidiasis	0.000	0.959	0.041
I08.2 Disorders of both aortic and tricuspid valves	0.041	0.959	0.000
I27 Other pulmonary heart diseases	0.041	0.959	0.000
G93.6 Cerebral oedema	0.000	0.960	0.040
G93.7 Reye's syndrome	0.000	0.960	0.040
I95.9 Hypotension, unspecified	0.039	0.961	0.000
G93.5 Compression of brain	0.000	0.961	0.039
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.038	0.961	0.000
G90-G99 Other disorders of the nervous system	0.000	0.962	0.038
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.037	0.963	0.000
I05.9 Mitral valve disease, unspecified	0.037	0.963	0.000
I08.0 Disorders of both mitral and aortic valves	0.037	0.963	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.964	0.036
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.964	0.036
N60.8 Other benign mammary dysplasias	0.036	0.964	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.000	0.965	0.035
G95 Other diseases of spinal cord	0.000	0.965	0.035
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.035	0.965	0.000
E87.2 Acidosis	0.035	0.965	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.035	0.965	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.966	0.034
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.966	0.034
I08.8 Other multiple valve diseases	0.033	0.966	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.032	0.967	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.032	0.967	0.000
I67.5 Moyamoya disease	0.032	0.967	0.000
I67.4 Hypertensive encephalopathy	0.032	0.967	0.000
I67.3 Progressive vascular leukoencephalopathy	0.032	0.967	0.000
I05.0 Mitral stenosis	0.031	0.968	0.000
G93.2 Benign intracranial hypertension	0.000	0.968	0.031
I71.0 Dissection of aorta [any part]	0.031	0.969	0.000
A07.1 Giardiasis [lambliasis]	0.001	0.970	0.029
I27.1 Kyphoscoliotic heart disease	0.029	0.970	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.971	0.029
G97.8 Other postprocedural disorders of nervous system	0.000	0.971	0.029
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.029	0.971	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.028	0.971	0.001
G96 Other disorders of central nervous system	0.000	0.971	0.029
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.028	0.972	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.972	0.028
I27.2 Other secondary pulmonary hypertension	0.028	0.972	0.000
G95.1 Vascular myelopathies	0.000	0.972	0.027
G92 Toxic encephalopathy	0.000	0.972	0.027
I67.9 Cerebrovascular disease, unspecified	0.027	0.973	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.973	0.027
I27.8 Other specified pulmonary heart diseases	0.027	0.973	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.973	0.026
I27.9 Pulmonary heart disease, unspecified	0.026	0.974	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.025	0.974	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.025	0.975	0.000
I69 Sequelae of cerebrovascular disease	0.025	0.975	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.976	0.024
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.976	0.024
A04.5 Campylobacter enteritis	0.000	0.976	0.024
G90 Disorders of autonomic nervous system	0.000	0.976	0.024
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.976	0.024
I63 Cerebral infarction	0.024	0.976	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.976	0.023
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.977	0.023
A08.4 Viral intestinal infection, unspecified	0.000	0.977	0.023
G91 Hydrocephalus	0.000	0.977	0.022
I88 Nonspecific lymphadenitis	0.022	0.978	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.978	0.022
I07.1 Tricuspid insufficiency	0.022	0.978	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.979	0.021
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.979	0.021
I67.8 Other specified cerebrovascular diseases	0.021	0.979	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.979	0.021
G96.8 Other specified disorders of central nervous system	0.000	0.979	0.021
I84 Haemorrhoids	0.021	0.979	0.000
G94.1 Hydrocephalus in neoplastic disease	0.000	0.979	0.021
I85 Oesophageal varices	0.021	0.979	0.000
I84.6 Residual haemorrhoidal skin tags	0.020	0.980	0.000
I84.9 Unspecified haemorrhoids without complication	0.020	0.980	0.000
I86 Varicose veins of other sites	0.020	0.980	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.019	0.981	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.019	0.981	0.000
I87 Other disorders of veins	0.019	0.981	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.981	0.019
I88.0 Nonspecific mesenteric lymphadenitis	0.019	0.981	0.000
I67.1 Cerebral aneurysm, nonruptured	0.019	0.981	0.000
I21 Acute myocardial infarction	0.019	0.981	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.981	0.018
G91.9 Hydrocephalus, unspecified	0.000	0.981	0.018
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.982	0.018
G96.0 Cerebrospinal fluid leak	0.000	0.982	0.018

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations