TreeWAS – Variant ID: rs17684427

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	0.968	0.032	0.000
# Top node	0.965	0.035	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.965	0.035	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.957	0.043	0.000
M20-M25 Other joint disorders	0.956	0.044	0.000
I60-I69 Cerebrovascular diseases	0.941	0.059	0.000
M20 Acquired deformities of fingers and toes	0.940	0.060	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.936	0.064	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.935	0.065	0.000
Chapter X Diseases of the respiratory system	0.933	0.067	0.000
J40-J47 Chronic lower respiratory diseases	0.924	0.076	0.000
M65-M68 Disorders of synovium and tendon	0.918	0.082	0.000
M20.4 Other hammer toe(s) (acquired)	0.918	0.082	0.000
J44 Other chronic obstructive pulmonary disease	0.914	0.086	0.000
I71 Aortic aneurysm and dissection	0.906	0.094	0.000
I67 Other cerebrovascular diseases	0.902	0.098	0.000
M70-M79 Other soft tissue disorders	0.894	0.106	0.000
M65 Synovitis and tenosynovitis	0.893	0.107	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.885	0.115	0.000
M22 Disorders of patella	0.882	0.118	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.880	0.120	0.000
Chapter V Mental and behavioural disorders	0.867	0.133	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.865	0.135	0.000
Chapter VIII Diseases of the ear and mastoid process	0.859	0.141	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.858	0.142	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.855	0.145	0.000
I05-I09 Chronic rheumatic heart diseases	0.850	0.150	0.000
I30-I52 Other forms of heart disease	0.847	0.153	0.000
I63 Cerebral infarction	0.846	0.154	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.837	0.163	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.836	0.164	0.000
O80-O84 Delivery	0.834	0.166	0.000
M24 Other specific joint derangements	0.829	0.170	0.000
I10-I15 Hypertensive diseases	0.828	0.172	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.817	0.183	0.000
O42 Premature rupture of membranes	0.816	0.184	0.000
M86-M90 Other osteopathies	0.814	0.186	0.000
I35 Nonrheumatic aortic valve disorders	0.813	0.187	0.000
O47 False labour	0.804	0.196	0.000
H65-H75 Diseases of middle ear and mastoid	0.804	0.196	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.797	0.203	0.000
I67.8 Other specified cerebrovascular diseases	0.796	0.204	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.794	0.206	0.000
M20.1 Hallux valgus (acquired)	0.793	0.207	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.790	0.210	0.000
I67.9 Cerebrovascular disease, unspecified	0.789	0.211	0.000
I67.1 Cerebral aneurysm, nonruptured	0.788	0.212	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.780	0.220	0.000
M20.5 Other deformities of toe(s) (acquired)	0.773	0.227	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.771	0.229	0.000
J95-J99 Other diseases of the respiratory system	0.770	0.230	0.000
I35.0 Aortic (valve) stenosis	0.770	0.230	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.767	0.233	0.000
E10-E14 Diabetes mellitus	0.767	0.233	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.766	0.233	0.000
M35 Other systemic involvement of connective tissue	0.762	0.238	0.000
M20.3 Other deformity of hallux (acquired)	0.758	0.242	0.000
I73 Other peripheral vascular diseases	0.758	0.242	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.758	0.242	0.000
J47 Bronchiectasis	0.754	0.246	0.000
O80 Single spontaneous delivery	0.754	0.246	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.754	0.246	0.000
M72 Fibroblastic disorders	0.753	0.247	0.000
M75 Shoulder lesions	0.752	0.248	0.000
O26.8 Other specified pregnancy-related conditions	0.751	0.249	0.000
I12 Hypertensive renal disease	0.750	0.250	0.000
I49 Other cardiac arrhythmias	0.749	0.251	0.000
M80-M85 Disorders of bone density and structure	0.747	0.253	0.000
M22.4 Chondromalacia patellae	0.746	0.254	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.743	0.257	0.000
M91-M94 Chondropathies	0.743	0.257	0.000
M60-M63 Disorders of muscles	0.743	0.257	0.000
I60 Subarachnoid haemorrhage	0.742	0.258	0.000
I69 Sequelae of cerebrovascular disease	0.740	0.260	0.000
E10 Insulin-dependent diabetes mellitus	0.737	0.263	0.000
M22.3 Other derangements of patella	0.736	0.264	0.000
H71 Cholesteatoma of middle ear	0.734	0.266	0.000
I70 Atherosclerosis	0.728	0.272	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.728	0.272	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.724	0.276	0.000
J40 Bronchitis, not specified as acute or chronic	0.722	0.278	0.000
O44 Placenta praevia	0.721	0.279	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.719	0.281	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.718	0.282	0.000
M22.8 Other disorders of patella	0.717	0.283	0.000
I07 Rheumatic tricuspid valve diseases	0.716	0.284	0.000
I27 Other pulmonary heart diseases	0.716	0.284	0.000
M77 Other enthesopathies	0.714	0.286	0.000
Chapter XXII Codes for special purposes	0.708	0.292	0.000
I78 Diseases of capillaries	0.707	0.293	0.000
O42.9 Premature rupture of membranes, unspecified	0.706	0.294	0.000
E10.9 Without complications	0.706	0.294	0.000
J42 Unspecified chronic bronchitis	0.705	0.294	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.703	0.297	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.703	0.297	0.000
M40-M43 Deforming dorsopathies	0.701	0.298	0.000
H60-H62 Diseases of external ear	0.699	0.301	0.000
O40 Polyhydramnios	0.699	0.301	0.000
I71.0 Dissection of aorta [any part]	0.697	0.303	0.000
I08 Multiple valve diseases	0.697	0.303	0.000
I45 Other conduction disorders	0.696	0.304	0.000
I34 Nonrheumatic mitral valve disorders	0.696	0.304	0.000
I00-I02 Acute rheumatic fever	0.694	0.306	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.693	0.307	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.692	0.308	0.000
M00-M03 Infectious arthropathies	0.691	0.308	0.000
O26.9 Pregnancy-related condition, unspecified	0.691	0.309	0.000
I72 Other aneurysm	0.690	0.310	0.000
O30 Multiple gestation	0.690	0.310	0.000
I63.9 Cerebral infarction, unspecified	0.690	0.310	0.000
I86 Varicose veins of other sites	0.689	0.311	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.687	0.313	0.000
O85-O92 Complications predominantly related to the puerperium	0.686	0.314	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.685	0.314	0.000
M34 Systemic sclerosis	0.685	0.314	0.000
M33 Dermatopolymyositis	0.685	0.314	0.000
M32 Systemic lupus erythematosus	0.685	0.314	0.000
M30 Polyarteritis nodosa and related conditions	0.685	0.314	0.000
O26.2 Pregnancy care of habitual aborter	0.685	0.315	0.000
I35.8 Other aortic valve disorders	0.684	0.316	0.000
M24.2 Disorder of ligament	0.680	0.320	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.679	0.321	0.000
I85 Oesophageal varices	0.678	0.322	0.000
F42 Obsessive-compulsive disorder	0.677	0.323	0.000
I12.0 Hypertensive renal disease with renal failure	0.676	0.324	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.674	0.326	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.674	0.326	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.673	0.327	0.000
M90 Osteopathies in diseases classified elsewhere	0.672	0.328	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.672	0.328	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.672	0.328	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.671	0.329	0.000
O45 Premature separation of placenta [abruptio placentae]	0.671	0.329	0.000
O43 Placental disorders	0.671	0.329	0.000
O41 Other disorders of amniotic fluid and membranes	0.671	0.329	0.000
O33 Maternal care for known or suspected disproportion	0.671	0.329	0.000
O31 Complications specific to multiple gestation	0.671	0.329	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.667	0.333	0.000
J41 Simple and mucopurulent chronic bronchitis	0.663	0.337	0.000
O00-O08 Pregnancy with abortive outcome	0.662	0.337	0.000
O36 Maternal care for other known or suspected foetal problems	0.662	0.338	0.000
E11 Non-insulin-dependent diabetes mellitus	0.660	0.340	0.000
M35.0 Sicca syndrome [Sjogren]	0.659	0.340	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.659	0.341	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.658	0.341	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.658	0.342	0.000
M66 Spontaneous rupture of synovium and tendon	0.658	0.342	0.000
M21 Other acquired deformities of limbs	0.658	0.342	0.000
I49.3 Ventricular premature depolarisation	0.658	0.342	0.000
M20.0 Deformity of finger(s)	0.657	0.343	0.000
Chapter VI Diseases of the nervous system	0.657	0.343	0.000
J43 Emphysema	0.657	0.343	0.000
J46 Status asthmaticus	0.656	0.344	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.655	0.345	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.655	0.345	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.653	0.347	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.653	0.347	0.000
O24 Diabetes mellitus in pregnancy	0.652	0.347	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.652	0.348	0.000
H73 Other disorders of tympanic membrane	0.650	0.350	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.650	0.350	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.649	0.351	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.649	0.351	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.649	0.351	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.649	0.351	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.649	0.351	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.648	0.352	0.000
I63.8 Other cerebral infarction	0.648	0.352	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.648	0.352	0.000
M71 Other bursopathies	0.647	0.353	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.647	0.353	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.647	0.353	0.000
I67.5 Moyamoya disease	0.647	0.353	0.000
I67.4 Hypertensive encephalopathy	0.647	0.353	0.000
I67.3 Progressive vascular leukoencephalopathy	0.647	0.353	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.647	0.353	0.000
O80.0 Spontaneous vertex delivery	0.646	0.354	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.645	0.355	0.000
F40 Phobic anxiety disorders	0.645	0.355	0.000
J98 Other respiratory disorders	0.644	0.356	0.000
O21 Excessive vomiting in pregnancy	0.643	0.357	0.000
I62 Other nontraumatic intracranial haemorrhage	0.642	0.357	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.642	0.358	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.642	0.358	0.000
M89 Other disorders of bone	0.641	0.359	0.000
F41 Other anxiety disorders	0.641	0.359	0.000
M76 Enthesopathies of lower limb, excluding foot	0.641	0.359	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.641	0.359	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.641	0.359	0.000
O80.9 Single spontaneous delivery, unspecified	0.641	0.359	0.000
M65.8 Other synovitis and tenosynovitis	0.640	0.359	0.000
M65.2 Calcific tendinitis	0.640	0.359	0.000
M65.1 Other infective (teno)synovitis	0.640	0.359	0.000
M65.0 Abscess of tendon sheath	0.640	0.359	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.639	0.361	0.000
M24.1 Other articular cartilage disorders	0.638	0.362	0.000
J60-J70 Lung diseases due to external agents	0.638	0.362	0.000
O29 Complications of anaesthesia during pregnancy	0.635	0.365	0.000
O28 Abnormal findings on antenatal screening of mother	0.635	0.365	0.000
O23 Infections of genito-urinary tract in pregnancy	0.635	0.365	0.000
O22 Venous complications in pregnancy	0.635	0.365	0.000
O25 Malnutrition in pregnancy	0.635	0.365	0.000
M22.1 Recurrent subluxation of patella	0.633	0.367	0.000
M22.9 Disorder of patella, unspecified	0.633	0.367	0.000
M22.0 Recurrent dislocation of patella	0.633	0.367	0.000
O81 Single delivery by forceps and vacuum extractor	0.632	0.368	0.000
M22.2 Patellofemoral disorders	0.632	0.368	0.000
M75.2 Bicipital tendinitis	0.632	0.368	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.631	0.369	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.631	0.369	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.631	0.369	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.631	0.369	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.631	0.369	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.631	0.369	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.631	0.369	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.625	0.375	0.000
O32.1 Maternal care for breech presentation	0.623	0.377	0.000
G90-G99 Other disorders of the nervous system	0.622	0.378	0.000
J84 Other interstitial pulmonary diseases	0.622	0.378	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.621	0.378	0.000
F80-F89 Disorders of psychological development	0.621	0.378	0.000
F70-F79 Mental retardation	0.621	0.378	0.000
F60-F69 Disorders of adult personality and behaviour	0.621	0.378	0.000
I07.1 Tricuspid insufficiency	0.621	0.379	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.620	0.380	0.000
I27.0 Primary pulmonary hypertension	0.618	0.382	0.000
E40-E46 Malnutrition	0.617	0.383	0.000
M87 Osteonecrosis	0.617	0.383	0.000
I85.9 Oesophageal varices without bleeding	0.614	0.386	0.000
H65 Nonsuppurative otitis media	0.614	0.386	0.000
O47.0 False labour before 37 completed weeks of gestation	0.613	0.387	0.000
F10.1 Harmful use	0.612	0.388	0.000
O47.9 False labour, unspecified	0.611	0.389	0.000
I09 Other rheumatic heart diseases	0.609	0.391	0.000
I06 Rheumatic aortic valve diseases	0.609	0.391	0.000
I05 Rheumatic mitral valve diseases	0.609	0.391	0.000
I50 Heart failure	0.608	0.392	0.000
J00-J06 Acute upper respiratory infections	0.607	0.393	0.000
I52 Other heart disorders in diseases classified elsewhere	0.607	0.393	0.000
I48 Atrial fibrillation and flutter	0.607	0.393	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.607	0.393	0.000
I41 Myocarditis in diseases classified elsewhere	0.607	0.393	0.000
I40 Acute myocarditis	0.607	0.393	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.607	0.393	0.000
I37 Pulmonary valve disorders	0.607	0.393	0.000
I36 Nonrheumatic tricuspid valve disorders	0.607	0.393	0.000
I32 Pericarditis in diseases classified elsewhere	0.607	0.393	0.000
J09-J18 Influenza and pneumonia	0.607	0.393	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.607	0.393	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.607	0.393	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.607	0.393	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.607	0.393	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.607	0.393	0.000
I27.2 Other secondary pulmonary hypertension	0.606	0.394	0.000
I88 Nonspecific lymphadenitis	0.606	0.394	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.605	0.395	0.000
H61 Other disorders of external ear	0.604	0.395	0.000
M75.5 Bursitis of shoulder	0.604	0.396	0.000
I77 Other disorders of arteries and arterioles	0.601	0.399	0.000
I11 Hypertensive heart disease	0.601	0.399	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.600	0.400	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.600	0.400	0.000
O26.5 Maternal hypotension syndrome	0.600	0.400	0.000
O26.4 Herpes gestationis	0.600	0.400	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.600	0.400	0.000
O26.1 Low weight gain in pregnancy	0.600	0.400	0.000
O26.0 Excessive weight gain in pregnancy	0.600	0.400	0.000
M05-M14 Inflammatory polyarthropathies	0.600	0.400	0.000
E11.9 Without complications	0.599	0.401	0.000
I30 Acute pericarditis	0.598	0.401	0.000
I81 Portal vein thrombosis	0.598	0.402	0.000
I61 Intracerebral haemorrhage	0.598	0.402	0.000
O84 Multiple delivery	0.598	0.402	0.000
O83 Other assisted single delivery	0.598	0.402	0.000
H69 Other disorders of Eustachian tube	0.597	0.403	0.000
I34.1 Mitral (valve) prolapse	0.596	0.404	0.000
I86.1 Scrotal varices	0.596	0.404	0.000
I73.9 Peripheral vascular disease, unspecified	0.596	0.404	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.595	0.405	0.000
M24.9 Joint derangement, unspecified	0.595	0.405	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.595	0.405	0.000
M24.7 Protrusio acetabuli	0.595	0.405	0.000
M24.6 Ankylosis of joint	0.595	0.405	0.000
M24.5 Contracture of joint	0.595	0.405	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.595	0.405	0.000
M24.0 Loose body in joint	0.595	0.405	0.000
F45 Somatoform disorders	0.595	0.405	0.000
I15 Secondary hypertension	0.594	0.406	0.000
I13 Hypertensive heart and renal disease	0.594	0.406	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.594	0.406	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.590	0.407	0.003
I45.1 Other and unspecified right bundle-branch block	0.593	0.407	0.000
M75.0 Adhesive capsulitis of shoulder	0.592	0.408	0.000
I12.9 Hypertensive renal disease without renal failure	0.592	0.408	0.000
I35.9 Aortic valve disorder, unspecified	0.591	0.409	0.000
I73.0 Raynaud's syndrome	0.590	0.410	0.000
I82 Other venous embolism and thrombosis	0.589	0.411	0.000
H66 Suppurative and unspecified otitis media	0.588	0.412	0.000
M31 Other necrotising vasculopathies	0.587	0.413	0.000
E20-E35 Disorders of other endocrine glands	0.586	0.414	0.000
I33 Acute and subacute endocarditis	0.585	0.415	0.000
O20 Haemorrhage in early pregnancy	0.585	0.415	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.585	0.415	0.000
M62 Other disorders of muscle	0.584	0.416	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.583	0.417	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.583	0.417	0.000
M75.1 Rotator cuff syndrome	0.582	0.418	0.000
M84 Disorders of continuity of bone	0.582	0.418	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.581	0.419	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.581	0.419	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.580	0.419	0.000
F99-F99 Unspecified mental disorder	0.580	0.420	0.000
I46 Cardiac arrest	0.580	0.420	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.580	0.420	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.579	0.421	0.000
I49.5 Sick sinus syndrome	0.579	0.421	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.579	0.421	0.000
I74 Arterial embolism and thrombosis	0.578	0.422	0.000
J45 Asthma	0.578	0.422	0.000
H74 Other disorders of middle ear and mastoid	0.577	0.422	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.576	0.423	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.576	0.423	0.000
H70 Mastoiditis and related conditions	0.576	0.423	0.000
H68 Eustachian salpingitis and obstruction	0.576	0.423	0.000
H67 Otitis media in diseases classified elsewhere	0.576	0.423	0.000
E13 Other specified diabetes mellitus	0.576	0.424	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.576	0.424	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.576	0.424	0.000
S60-S69 Injuries to the wrist and hand	0.575	0.425	0.000
M67 Other disorders of synovium and tendon	0.574	0.426	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.573	0.427	0.000
I38 Endocarditis, valve unspecified	0.572	0.428	0.000
O46.9 Antepartum haemorrhage, unspecified	0.572	0.428	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.572	0.428	0.000
Chapter VII Diseases of the eye and adnexa	0.572	0.428	0.000
I86.4 Gastric varices	0.572	0.428	0.000
M86 Osteomyelitis	0.570	0.429	0.000
M90.7 Fracture of bone in neoplastic disease	0.570	0.429	0.000
F48 Other neurotic disorders	0.569	0.431	0.000
F44 Dissociative [conversion] disorders	0.569	0.431	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.567	0.432	0.000
O48 Prolonged pregnancy	0.567	0.432	0.000
O44.1 Placenta praevia with haemorrhage	0.567	0.433	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.566	0.433	0.000
I28 Other diseases of pulmonary vessels	0.566	0.434	0.000
I67.2 Cerebral atherosclerosis	0.565	0.435	0.000
M94 Other disorders of cartilage	0.564	0.436	0.000
I69.3 Sequelae of cerebral infarction	0.562	0.438	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.562	0.438	0.000
E10.3 With ophthalmic complications	0.561	0.439	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.561	0.439	0.000
E10.1 With ketoacidosis	0.561	0.439	0.000
E16 Other disorders of pancreatic internal secretion	0.560	0.440	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.560	0.440	0.000
O60-O75 Complications of labour and delivery	0.560	0.440	0.000
M85 Other disorders of bone density and structure	0.559	0.441	0.000
F30-F39 Mood [affective] disorders	0.558	0.442	0.000
M88 Paget's disease of bone [osteitis deformans]	0.558	0.442	0.000
M75.3 Calcific tendinitis of shoulder	0.556	0.443	0.000
M93 Other osteochondropathies	0.556	0.444	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.556	0.444	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.553	0.447	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.553	0.447	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.553	0.447	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.553	0.447	0.000
O34.6 Maternal care for abnormality of vagina	0.553	0.447	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.553	0.447	0.000
O34.4 Maternal care for other abnormalities of cervix	0.553	0.447	0.000
O34.3 Maternal care for cervical incompetence	0.553	0.447	0.000
O34.1 Maternal care for tumour of corpus uteri	0.553	0.447	0.000
O34.0 Maternal care for congenital malformation of uterus	0.553	0.447	0.000
J96 Respiratory failure, not elsewhere classified	0.552	0.448	0.000
M77.4 Metatarsalgia	0.552	0.448	0.000
F41.9 Anxiety disorder, unspecified	0.551	0.449	0.000
E12 Malnutrition-related diabetes mellitus	0.550	0.450	0.000
J98.8 Other specified respiratory disorders	0.550	0.450	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.549	0.451	0.000
J80 Adult respiratory distress syndrome	0.548	0.452	0.000
I42 Cardiomyopathy	0.546	0.454	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.546	0.454	0.000
M35.8 Other specified systemic involvement of connective tissue	0.546	0.454	0.000
M35.7 Hypermobility syndrome	0.546	0.454	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.546	0.454	0.000
M35.5 Multifocal fibrosclerosis	0.546	0.454	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.546	0.454	0.000
M35.2 Behcet's disease	0.546	0.454	0.000
M35.1 Other overlap syndromes	0.546	0.454	0.000
I49.9 Cardiac arrhythmia, unspecified	0.546	0.454	0.000
D50-D53 Nutritional anaemias	0.544	0.456	0.000
M45-M49 Spondylopathies	0.544	0.456	0.000
J81 Pulmonary oedema	0.544	0.456	0.000
M77.0 Medial epicondylitis	0.544	0.456	0.000
I49.4 Other and unspecified premature depolarisation	0.544	0.456	0.000
M41 Scoliosis	0.544	0.456	0.000
I73.8 Other specified peripheral vascular diseases	0.544	0.456	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.544	0.456	0.000
M80 Osteoporosis with pathological fracture	0.543	0.456	0.000
M79.1 Myalgia	0.543	0.457	0.000
M25 Other joint disorders, not elsewhere classified	0.543	0.457	0.000
O03 Spontaneous abortion	0.541	0.458	0.000
I89.0 Lymphoedema, not elsewhere classified	0.541	0.459	0.000
O80.8 Other single spontaneous delivery	0.540	0.459	0.000
O80.1 Spontaneous breech delivery	0.540	0.459	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.541	0.459	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.540	0.460	0.000
O32.8 Maternal care for other malpresentation of foetus	0.540	0.460	0.000
O32.6 Maternal care for compound presentation	0.540	0.460	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.540	0.460	0.000
O32.4 Maternal care for high head at term	0.540	0.460	0.000
O32.3 Maternal care for face, brow and chin presentation	0.540	0.460	0.000
O32.2 Maternal care for transverse and oblique lie	0.540	0.460	0.000
O32.0 Maternal care for unstable lie	0.540	0.460	0.000
H73.8 Other specified disorders of tympanic membrane	0.540	0.460	0.000
M72.9 Fibroblastic disorder, unspecified	0.540	0.460	0.000
M72.8 Other fibroblastic disorders	0.540	0.460	0.000
M72.6 Necrotizing fasciitis	0.540	0.460	0.000
M72.5 Fasciitis, not elsewhere classified	0.540	0.460	0.000
M72.4 Pseudosarcomatous fibromatosis	0.540	0.460	0.000
M72.3 Nodular fasciitis	0.540	0.460	0.000
M72.2 Plantar fascial fibromatosis	0.540	0.460	0.000
M72.1 Knuckle pads	0.540	0.460	0.000
F43 Reaction to severe stress, and adjustment disorders	0.540	0.460	0.000
I49.8 Other specified cardiac arrhythmias	0.540	0.460	0.000
M75.8 Other shoulder lesions	0.539	0.461	0.000
M75.9 Shoulder lesion, unspecified	0.539	0.461	0.000
F40.2 Specific (isolated) phobias	0.538	0.462	0.000
H61.2 Impacted cerumen	0.538	0.462	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.538	0.462	0.000
I49.2 Junctional premature depolarisation	0.537	0.463	0.000
I49.1 Atrial premature depolarisation	0.537	0.463	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.537	0.463	0.000
H72 Perforation of tympanic membrane	0.537	0.463	0.000
I87 Other disorders of veins	0.536	0.464	0.000
M83 Adult osteomalacia	0.535	0.464	0.000
M82 Osteoporosis in diseases classified elsewhere	0.535	0.464	0.000
I72.3 Aneurysm of iliac artery	0.535	0.465	0.000
F50 Eating disorders	0.535	0.465	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.534	0.466	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.533	0.467	0.000
Q80-Q89 Other congenital malformations	0.533	0.467	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.533	0.467	0.000
Q35-Q37 Cleft lip and cleft palate	0.533	0.467	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.533	0.467	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.533	0.467	0.000
Q00-Q07 Congenital malformations of the nervous system	0.533	0.467	0.000
M92 Other juvenile osteochondrosis	0.532	0.467	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.532	0.467	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.532	0.467	0.000
M61 Calcification and ossification of muscle	0.532	0.467	0.000
M60 Myositis	0.532	0.467	0.000
I60.8 Other subarachnoid haemorrhage	0.532	0.468	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.532	0.468	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.532	0.468	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.532	0.468	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.532	0.468	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.532	0.468	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.532	0.468	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.532	0.468	0.000
E10.4 With neurological complications	0.532	0.468	0.000
O82 Single delivery by Caesarean section	0.531	0.469	0.000
I49.0 Ventricular fibrillation and flutter	0.531	0.469	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.530	0.469	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.530	0.469	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.530	0.469	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.530	0.470	0.000
E65-E68 Obesity and other hyperalimentation	0.529	0.471	0.000
E10.8 With unspecified complications	0.528	0.472	0.000
E10.7 With multiple complications	0.528	0.472	0.000
E10.6 With other specified complications	0.528	0.472	0.000
E10.5 With peripheral circulatory complications	0.528	0.472	0.000
E10.2 With renal complications	0.528	0.472	0.000
E10.0 With coma	0.528	0.472	0.000
G40-G47 Episodic and paroxysmal disorders	0.525	0.475	0.000
J30-J39 Other diseases of upper respiratory tract	0.525	0.475	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.525	0.475	0.000
M77.1 Lateral epicondylitis	0.524	0.476	0.000
I70.9 Generalised and unspecified atherosclerosis	0.522	0.478	0.000
I70.8 Atherosclerosis of other arteries	0.522	0.478	0.000
I70.1 Atherosclerosis of renal artery	0.522	0.478	0.000
I70.0 Atherosclerosis of aorta	0.522	0.478	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.522	0.478	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.522	0.478	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.522	0.478	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.522	0.478	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.522	0.478	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.522	0.478	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.522	0.478	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.522	0.478	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.522	0.478	0.000
I45.9 Conduction disorder, unspecified	0.519	0.481	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.519	0.481	0.000
O46.8 Other antepartum haemorrhage	0.519	0.481	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.519	0.481	0.000
I10 Essential (primary) hypertension	0.519	0.481	0.000
E11.0 With coma	0.518	0.482	0.000
M89.9 Disorder of bone, unspecified	0.517	0.483	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.517	0.483	0.000
S68 Traumatic amputation of wrist and hand	0.517	0.483	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.515	0.484	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.515	0.484	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations