TreeWAS – Variant ID: rs17735173

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
E10-E14 Diabetes mellitus	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter V Mental and behavioural disorders	0.997	0.003
M45-M49 Spondylopathies	0.996	0.004
M20 Acquired deformities of fingers and toes	0.992	0.008
M20.2 Hallux rigidus	0.991	0.009
Chapter VI Diseases of the nervous system	0.989	0.011
Chapter XV Pregnancy, childbirth and the puerperium	0.987	0.013
M48 Other spondylopathies	0.987	0.013
S80-S89 Injuries to the knee and lower leg	0.983	0.017
Chapter VIII Diseases of the ear and mastoid process	0.982	0.018
G90-G99 Other disorders of the nervous system	0.981	0.019
E70-E90 Metabolic disorders	0.981	0.019
M48.0 Spinal stenosis	0.978	0.022
G99 Other disorders of nervous system in diseases classified elsewhere	0.976	0.024
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.976	0.024
E20-E35 Disorders of other endocrine glands	0.974	0.026
M48.06 Spinal stenosis (Lumbar region)	0.973	0.027
E11.9 Without complications	0.971	0.029
G99.2 Myelopathy in diseases classified elsewhere	0.969	0.031
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.968	0.032
H65-H75 Diseases of middle ear and mastoid	0.967	0.033
S82 Fracture of lower leg, including ankle	0.954	0.046
Chapter XX External causes of morbidity and mortality	0.940	0.060
F00-F09 Organic, including symptomatic, mental disorders	0.939	0.061
E83 Disorders of mineral metabolism	0.937	0.063
F10 Mental and behavioural disorders due to use of alcohol	0.934	0.066
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.933	0.067
E87 Other disorders of fluid, electrolyte and acid-base balance	0.925	0.075
E10 Insulin-dependent diabetes mellitus	0.921	0.079
E11.3 With ophthalmic complications	0.921	0.079
H72 Perforation of tympanic membrane	0.917	0.083
E87.1 Hypo-osmolality and hyponatraemia	0.916	0.084
M22 Disorders of patella	0.905	0.095
H80-H83 Diseases of inner ear	0.903	0.097
S10-S19 Injuries to the neck	0.902	0.098
S82.3 Fracture of lower end of tibia	0.901	0.099
M24 Other specific joint derangements	0.900	0.100
S20-S29 Injuries to the thorax	0.897	0.103
E83.5 Disorders of calcium metabolism	0.897	0.103
O20-O29 Other maternal disorders predominantly related to pregnancy	0.889	0.111
O47 False labour	0.886	0.114
E16 Other disorders of pancreatic internal secretion	0.886	0.114
T36-T50 Poisoning by drugs, medicaments and biological substances	0.885	0.115
G50-G59 Nerve, nerve root and plexus disorders	0.885	0.115
O48 Prolonged pregnancy	0.883	0.117
S82.2 Fracture of shaft of tibia	0.874	0.126
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.874	0.126
M45 Ankylosing spondylitis	0.871	0.129
M05-M14 Inflammatory polyarthropathies	0.870	0.130
M65-M68 Disorders of synovium and tendon	0.867	0.133
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.866	0.134
E11.4 With neurological complications	0.863	0.137
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.861	0.139
F30-F39 Mood [affective] disorders	0.860	0.140
S82.30 Fracture of lower end of tibia (closed)	0.859	0.141
E11.5 With peripheral circulatory complications	0.855	0.145
O43 Placental disorders	0.855	0.145
M86-M90 Other osteopathies	0.851	0.149
F10.1 Harmful use	0.851	0.149
M48.09 Spinal stenosis (Site unspecified)	0.851	0.149
W20-W49 Exposure to inanimate mechanical forces	0.850	0.150
E11.6 With other specified complications	0.848	0.152
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.846	0.154
M22.8 Other disorders of patella	0.845	0.155
W00-W19 Falls	0.842	0.158
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.841	0.159
M34 Systemic sclerosis	0.839	0.161
H72.9 Perforation of tympanic membrane, unspecified	0.839	0.161
M40-M43 Deforming dorsopathies	0.838	0.162
E87.6 Hypokalaemia	0.837	0.163
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.835	0.165
E16.2 Hypoglycaemia, unspecified	0.834	0.166
O32 Maternal care for known or suspected malpresentation of foetus	0.827	0.173
H83 Other diseases of inner ear	0.827	0.173
E26 Hyperaldosteronism	0.825	0.175
Chapter IX Diseases of the circulatory system	0.823	0.177
F31 Bipolar affective disorder	0.823	0.177
E10.3 With ophthalmic complications	0.821	0.179
O47.1 False labour at or after 37 completed weeks of gestation	0.820	0.179
O94-O99 Other obstetric conditions, not elsewhere classified	0.819	0.181
S22 Fracture of rib(s), sternum and thoracic spine	0.818	0.182
F10.3 Withdrawal state	0.816	0.184
E11.2 With renal complications	0.816	0.184
S80 Superficial injury of lower leg	0.816	0.184
S60-S69 Injuries to the wrist and hand	0.813	0.187
M25 Other joint disorders, not elsewhere classified	0.813	0.187
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.813	0.187
M20.3 Other deformity of hallux (acquired)	0.813	0.187
F05 Delirium, not induced by alcohol and other psychoactive substances	0.813	0.187
E27 Other disorders of adrenal gland	0.811	0.189
I30-I52 Other forms of heart disease	0.810	0.190
E20 Hypoparathyroidism	0.809	0.191
E23 Hypofunction and other disorders of pituitary gland	0.809	0.191
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.807	0.192
H69 Other disorders of Eustachian tube	0.806	0.194
M35 Other systemic involvement of connective tissue	0.804	0.196
S70-S79 Injuries to the hip and thigh	0.804	0.196
H71 Cholesteatoma of middle ear	0.803	0.197
I50 Heart failure	0.802	0.198
X40-X49 Accidental poisoning by and exposure to noxious substances	0.800	0.200
G20-G26 Extrapyramidal and movement disorders	0.800	0.200
M20.6 Acquired deformity of toe(s), unspecified	0.798	0.202
G00-G09 Inflammatory diseases of the central nervous system	0.797	0.202
T20-T25 Burns and corrosions of external body surface, specified by site	0.796	0.204
M32 Systemic lupus erythematosus	0.791	0.209
I47 Paroxysmal tachycardia	0.789	0.211
M48.5 Collapsed vertebra, not elsewhere classified	0.789	0.211
M21 Other acquired deformities of limbs	0.787	0.213
M47 Spondylosis	0.787	0.213
F03 Unspecified dementia	0.785	0.215
S22.4 Multiple fractures of ribs	0.784	0.216
F17 Mental and behavioural disorders due to use of tobacco	0.783	0.217
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.783	0.217
M45.X9 Ankylosing spondylitis (Site unspecified)	0.782	0.218
M24.0 Loose body in joint	0.780	0.220
I50.0 Congestive heart failure	0.779	0.221
E11.8 With unspecified complications	0.777	0.223
S90-S99 Injuries to the ankle and foot	0.775	0.225
E83.4 Disorders of magnesium metabolism	0.774	0.226
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.773	0.227
O43.8 Other placental disorders	0.772	0.228
S27 Injury of other and unspecified intrathoracic organs	0.772	0.228
H83.0 Labyrinthitis	0.772	0.228
E89.0 Postprocedural hypothyroidism	0.770	0.230
F80-F89 Disorders of psychological development	0.770	0.230
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.769	0.231
S82.20 Fracture of shaft of tibia (closed)	0.769	0.231
H73 Other disorders of tympanic membrane	0.768	0.232
E10.2 With renal complications	0.767	0.233
O85-O92 Complications predominantly related to the puerperium	0.766	0.234
G51 Facial nerve disorders	0.766	0.234
M80-M85 Disorders of bone density and structure	0.766	0.234
G59 Mononeuropathy in diseases classified elsewhere	0.764	0.236
M66 Spontaneous rupture of synovium and tendon	0.763	0.237
S82.5 Fracture of medial malleolus	0.763	0.237
M05 Seropositive rheumatoid arthritis	0.761	0.239
S22.40 Multiple fractures of ribs (closed)	0.760	0.240
G96 Other disorders of central nervous system	0.760	0.240
O34 Maternal care for known or suspected abnormality of pelvic organs	0.759	0.241
E40-E46 Malnutrition	0.758	0.242
M06 Other rheumatoid arthritis	0.758	0.242
H72.8 Other perforations of tympanic membrane	0.758	0.242
M60-M63 Disorders of muscles	0.755	0.245
G91 Hydrocephalus	0.755	0.245
M20.4 Other hammer toe(s) (acquired)	0.753	0.247
G95 Other diseases of spinal cord	0.753	0.247
H74 Other disorders of middle ear and mastoid	0.751	0.249
F60-F69 Disorders of adult personality and behaviour	0.751	0.249
M91-M94 Chondropathies	0.751	0.249
O44 Placenta praevia	0.750	0.250
T00-T07 Injuries involving multiple body regions	0.749	0.251
F29 Unspecified nonorganic psychosis	0.748	0.252
G70-G73 Diseases of myoneural junction and muscle	0.748	0.252
F10.0 Acute intoxication	0.747	0.253
O40 Polyhydramnios	0.746	0.254
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.744	0.256
I47.1 Supraventricular tachycardia	0.743	0.257
E73 Lactose intolerance	0.742	0.258
I50.1 Left ventricular failure	0.740	0.260
V01-V09 Pedestrian injured in transport accident	0.739	0.261
O47.0 False labour before 37 completed weeks of gestation	0.739	0.261
S82.21 Fracture of shaft of tibia (open)	0.738	0.262
S86 Injury of muscle and tendon at lower leg level	0.738	0.262
O26 Maternal care for other conditions predominantly related to pregnancy	0.737	0.263
M25.7 Osteophyte	0.735	0.265
M47.2 Other spondylosis with radiculopathy	0.734	0.266
G30-G32 Other degenerative diseases of the nervous system	0.732	0.268
F02 Dementia in other diseases classified elsewhere	0.730	0.270
M00-M03 Infectious arthropathies	0.730	0.270
H72.0 Central perforation of tympanic membrane	0.728	0.272
F11 Mental and behavioural disorders due to use of opioids	0.728	0.272
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.726	0.274
I20-I25 Ischaemic heart diseases	0.726	0.274
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.726	0.274
Q38-Q45 Other congenital malformations of the digestive system	0.725	0.275
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.725	0.275
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.725	0.275
X20-X29 Contact with venomous animals and plants	0.724	0.276
S11 Open wound of neck	0.724	0.276
G80-G83 Cerebral palsy and other paralytic syndromes	0.723	0.277
M48.00 Spinal stenosis (Multiple sites in spine)	0.723	0.277
T15-T19 Effects of foreign body entering through natural orifice	0.722	0.278
F05.9 Delirium, unspecified	0.722	0.278
O21 Excessive vomiting in pregnancy	0.722	0.278
F31.0 Bipolar affective disorder, current episode hypomanic	0.721	0.279
F31.9 Bipolar affective disorder, unspecified	0.721	0.279
E10.5 With peripheral circulatory complications	0.721	0.279
I42 Cardiomyopathy	0.719	0.281
E16.0 Drug-induced hypoglycaemia without coma	0.719	0.281
I24 Other acute ischaemic heart diseases	0.719	0.281
E26.0 Primary hyperaldosteronism	0.718	0.281
F17.2 Dependence syndrome	0.718	0.282
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
O80-O84 Delivery	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
O23 Infections of genito-urinary tract in pregnancy	0.717	0.283
S12 Fracture of neck	0.716	0.284
E11.7 With multiple complications	0.716	0.284
E11.0 With coma	0.716	0.284
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.716	0.284
V20-V29 Motorcycle rider injured in transport accident	0.716	0.284
T33-T35 Frostbite	0.715	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284
M35.3 Polymyalgia rheumatica	0.715	0.285
M24.2 Disorder of ligament	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
X60-X84 Intentional self-harm	0.714	0.285
F00 Dementia in Alzheimer's disease	0.714	0.286
T42.4 Benzodiazepines	0.714	0.286
M49 Spondylopathies in diseases classified elsewhere	0.714	0.286
M50-M54 Other dorsopathies	0.713	0.287
O30 Multiple gestation	0.711	0.289
F10.9 Unspecified mental and behavioural disorder	0.710	0.290
W44 Foreign body entering into or through eye or natural orifice	0.710	0.290
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.710	0.290
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.710	0.290
M89 Other disorders of bone	0.710	0.290
W50-W64 Exposure to animate mechanical forces	0.709	0.290
E29 Testicular dysfunction	0.709	0.291
E22 Hyperfunction of pituitary gland	0.709	0.291
E10.9 Without complications	0.709	0.291
S81 Open wound of lower leg	0.708	0.292
M48.9 Spondylopathy, unspecified	0.708	0.292
M48.8 Other specified spondylopathies	0.708	0.292
M48.4 Fatigue fracture of vertebra	0.708	0.292
M48.3 Traumatic spondylopathy	0.708	0.292
M48.2 Kissing spine	0.708	0.292
M48.1 Ankylosing hyperostosis [Forestier]	0.708	0.292
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.708	0.292
F30 Manic episode	0.707	0.293
Chapter XXII Codes for special purposes	0.706	0.294
F01 Vascular dementia	0.706	0.294
S82.6 Fracture of lateral malleolus	0.706	0.294
S88 Traumatic amputation of lower leg	0.705	0.295
S87 Crushing injury of lower leg	0.705	0.295
S85 Injury of blood vessels at lower leg level	0.705	0.295
S84 Injury of nerves at lower leg level	0.705	0.295
S19 Other and unspecified injuries of neck	0.704	0.296
G94 Other disorders of brain in diseases classified elsewhere	0.703	0.297
G90 Disorders of autonomic nervous system	0.703	0.297
G98 Other disorders of nervous system, not elsewhere classified	0.703	0.297
G92 Toxic encephalopathy	0.703	0.297
Chapter VII Diseases of the eye and adnexa	0.703	0.297
E85 Amyloidosis	0.703	0.297
E84 Cystic fibrosis	0.703	0.297
E79 Disorders of purine and pyrimidine metabolism	0.703	0.297
E77 Disorders of glycoprotein metabolism	0.703	0.297
E76 Disorders of glycosaminoglycan metabolism	0.703	0.297
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.703	0.297
E74 Other disorders of carbohydrate metabolism	0.703	0.297
E72 Other disorders of amino-acid metabolism	0.703	0.297
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.703	0.297
E70 Disorders of aromatic amino-acid metabolism	0.703	0.297
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.703	0.297
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.701	0.298
M48.05 Spinal stenosis (Thoracolumbar region)	0.701	0.298
M48.04 Spinal stenosis (Thoracic region)	0.701	0.298
M48.03 Spinal stenosis (Cervicothoracic region)	0.701	0.298
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.701	0.298
S40-S49 Injuries to the shoulder and upper arm	0.701	0.299
M24.8 Other specific joint derangements, not elsewhere classified	0.700	0.300
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.700	0.300
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.700	0.300
O45 Premature separation of placenta [abruptio placentae]	0.700	0.300
O33 Maternal care for known or suspected disproportion	0.700	0.300
O31 Complications specific to multiple gestation	0.700	0.300
E83.3 Disorders of phosphorus metabolism	0.699	0.301
M14 Arthropathies in other diseases classified elsewhere	0.699	0.301
S50-S59 Injuries to the elbow and forearm	0.699	0.301
H80 Otosclerosis	0.698	0.302
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.698	0.302
E35 Disorders of endocrine glands in diseases classified elsewhere	0.698	0.302
E34 Other endocrine disorders	0.698	0.302
E32 Diseases of thymus	0.698	0.302
E31 Polyglandular dysfunction	0.698	0.302
E30 Disorders of puberty, not elsewhere classified	0.698	0.302
E25 Adrenogenital disorders	0.698	0.302
G11 Hereditary ataxia	0.697	0.303
W06 Fall involving bed	0.697	0.303
M24.1 Other articular cartilage disorders	0.696	0.304
Y60-Y69 Misadventures to patients during surgical and medical care	0.695	0.305
M65 Synovitis and tenosynovitis	0.695	0.305
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.694	0.306
F18 Mental and behavioural disorders due to use of volatile solvents	0.694	0.306
F16 Mental and behavioural disorders due to use of hallucinogens	0.694	0.306
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.694	0.306
F14 Mental and behavioural disorders due to use of cocaine	0.694	0.306
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.694	0.306
O46 Antepartum haemorrhage, not elsewhere classified	0.694	0.306
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.693	0.307
H70 Mastoiditis and related conditions	0.693	0.307
H68 Eustachian salpingitis and obstruction	0.693	0.307
H67 Otitis media in diseases classified elsewhere	0.693	0.307
F12 Mental and behavioural disorders due to use of cannabinoids	0.693	0.307
M46 Other inflammatory spondylopathies	0.691	0.308
E20.9 Hypoparathyroidism, unspecified	0.691	0.309
E23.0 Hypopituitarism	0.690	0.310
H69.9 Eustachian tube disorder, unspecified	0.690	0.310
H65 Nonsuppurative otitis media	0.689	0.311
E11.1 With ketoacidosis	0.688	0.312
M66.0 Rupture of popliteal cyst	0.688	0.312
S64 Injury of nerves at wrist and hand level	0.688	0.312
E28 Ovarian dysfunction	0.686	0.314
S60 Superficial injury of wrist and hand	0.685	0.315
T66-T78 Other and unspecified effects of external causes	0.685	0.315
M34.9 Systemic sclerosis, unspecified	0.685	0.315
I24.8 Other forms of acute ischaemic heart disease	0.684	0.316
F99-F99 Unspecified mental disorder	0.684	0.316
G53 Cranial nerve disorders in diseases classified elsewhere	0.684	0.316
S82.9 Fracture of lower leg, part unspecified	0.684	0.316
S82.7 Multiple fractures of lower leg	0.684	0.316
O32.0 Maternal care for unstable lie	0.684	0.316
W03 Other fall on same level due to collision with, or pushing by, another person	0.683	0.317
O24 Diabetes mellitus in pregnancy	0.683	0.317
M05.9 Seropositive rheumatoid arthritis, unspecified	0.682	0.318
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.682	0.318
E24 Cushing's syndrome	0.681	0.319
W29 Contact with other powered hand tools and household machinery	0.681	0.319
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.679	0.321
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.679	0.321
W21 Striking against or struck by sports equipment	0.678	0.321
V40-V49 Car occupant injured in transport accident	0.678	0.322
I30 Acute pericarditis	0.678	0.322
E88 Other metabolic disorders	0.677	0.323
X50-X57 Overexertion, travel and privation	0.676	0.324
G59.0 Diabetic mononeuropathy	0.676	0.324
M43 Other deforming dorsopathies	0.675	0.325
F23 Acute and transient psychotic disorders	0.674	0.326
Y35-Y36 Legal intervention and operations of war	0.674	0.326
Y10-Y34 Event of undetermined intent	0.674	0.326
Y00-Y09 Assault	0.674	0.326
X85-X99 Assault	0.674	0.326
X58-X59 Accidental exposure to other and unspecified factors	0.674	0.326
X30-X39 Exposure to forces of nature	0.674	0.326
X10-X19 Contact with heat and hot substances	0.674	0.326
X00-X09 Exposure to smoke, fire and flames	0.674	0.326
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.674	0.326
W75-W84 Other accidental threats to breathing	0.674	0.326
W65-W74 Accidental drowning and submersion	0.674	0.326
V98-V99 Other and unspecified transport accidents	0.674	0.326
V95-V97 Air and space transport accidents	0.674	0.326
V90-V94 Water transport accidents	0.674	0.326
V70-V79 Bus occupant injured in transport accident	0.674	0.326
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.674	0.326
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.674	0.326
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.674	0.326
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.673	0.327
F09 Unspecified organic or symptomatic mental disorder	0.673	0.327
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.673	0.327
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.673	0.327
E83.9 Disorder of mineral metabolism, unspecified	0.672	0.328
E83.8 Other disorders of mineral metabolism	0.672	0.328
E83.2 Disorders of zinc metabolism	0.672	0.328
E83.0 Disorders of copper metabolism	0.672	0.328
S82.31 Fracture of lower end of tibia (open)	0.672	0.328
E27.4 Other and unspecified adrenocortical insufficiency	0.671	0.329
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.671	0.329
Q80-Q89 Other congenital malformations	0.671	0.329
M41 Scoliosis	0.670	0.330
S83.6 Sprain and strain of other and unspecified parts of knee	0.670	0.330
F10.8 Other mental and behavioural disorders	0.669	0.330
F10.7 Residual and late-onset psychotic disorder	0.669	0.330
F10.6 Amnesic syndrome	0.669	0.330
F10.5 Psychotic disorder	0.669	0.330
E15 Nondiabetic hypoglycaemic coma	0.669	0.331
W10 Fall on and from stairs and steps	0.666	0.334
I31 Other diseases of pericardium	0.666	0.334
T79-T79 Certain early complications of trauma	0.665	0.335
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.665	0.335
H81 Disorders of vestibular function	0.665	0.335
M86 Osteomyelitis	0.664	0.336
E10.4 With neurological complications	0.663	0.336
H53-H54 Visual disturbances and blindness	0.664	0.336
E87.4 Mixed disorder of acid-base balance	0.663	0.337
Q60-Q64 Congenital malformations of the urinary system	0.663	0.337
G51.0 Bell's palsy	0.661	0.339
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.661	0.339
H66 Suppurative and unspecified otitis media	0.661	0.339
M34.1 CR(E)ST syndrome	0.661	0.339
V10-V19 Pedal cyclist injured in transport accident	0.661	0.339
M24.07 Loose body in joint (Ankle and foot)	0.660	0.339
E10.8 With unspecified complications	0.660	0.340
E10.7 With multiple complications	0.660	0.340
E10.6 With other specified complications	0.660	0.340
E10.0 With coma	0.660	0.340
S80.1 Contusion of other and unspecified parts of lower leg	0.660	0.340
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.658	0.342
F10.4 Withdrawal state with delirium	0.658	0.342
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.658	0.342
H72.2 Other marginal perforations of tympanic membrane	0.658	0.342
H72.1 Attic perforation of tympanic membrane	0.658	0.342
M22.2 Patellofemoral disorders	0.657	0.343
E86 Volume depletion	0.657	0.343
S83.2 Tear of meniscus, current	0.656	0.344
I47.2 Ventricular tachycardia	0.655	0.345
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.655	0.345
E89.2 Postprocedural hypoparathyroidism	0.654	0.346
E21.0 Primary hyperparathyroidism	0.654	0.346
O32.4 Maternal care for high head at term	0.654	0.346
O35 Maternal care for known or suspected foetal abnormality and damage	0.653	0.347
I36 Nonrheumatic tricuspid valve disorders	0.652	0.348
W17 Other fall from one level to another	0.652	0.348
W49 Exposure to other and unspecified inanimate mechanical forces	0.651	0.349
T23 Burn and corrosion of wrist and hand	0.651	0.349
O41 Other disorders of amniotic fluid and membranes	0.649	0.350
M22.1 Recurrent subluxation of patella	0.649	0.351
M22.9 Disorder of patella, unspecified	0.649	0.351
M22.0 Recurrent dislocation of patella	0.649	0.351
O26.8 Other specified pregnancy-related conditions	0.649	0.351
I47.0 Reentry ventricular arrhythmia	0.649	0.351
H82 Vertiginous syndromes in diseases classified elsewhere	0.647	0.353
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.647	0.353
F10.2 Dependence syndrome	0.647	0.353
W07 Fall involving chair	0.647	0.353
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.647	0.353
M25.6 Stiffness of joint, not elsewhere classified	0.647	0.353
S17 Crushing injury of neck	0.646	0.353
S15 Injury of blood vessels at neck level	0.646	0.353
S14 Injury of nerves and spinal cord at neck level	0.646	0.353
S10 Superficial injury of neck	0.646	0.353
S18 Traumatic amputation at neck level	0.646	0.353
S16 Injury of muscle and tendon at neck level	0.646	0.353
M24.9 Joint derangement, unspecified	0.645	0.355
M24.7 Protrusio acetabuli	0.645	0.355
M24.6 Ankylosis of joint	0.645	0.355
M24.5 Contracture of joint	0.645	0.355
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.645	0.355
E21.3 Hyperparathyroidism, unspecified	0.645	0.355
O00-O08 Pregnancy with abortive outcome	0.644	0.355
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.644	0.356
M22.3 Other derangements of patella	0.644	0.356
S82.8 Fractures of other parts of lower leg	0.644	0.356
S82.4 Fracture of fibula alone	0.644	0.356
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.643	0.356
S26 Injury of heart	0.643	0.356
S25 Injury of blood vessels of thorax	0.643	0.356
S24 Injury of nerves and spinal cord at thorax level	0.643	0.356
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.643	0.356
S21 Open wound of thorax	0.643	0.356
G58 Other mononeuropathies	0.643	0.357
Q50-Q56 Congenital malformations of genital organs	0.643	0.357
E87.3 Alkalosis	0.642	0.357
X49.9 Unspecified place	0.642	0.358
M87 Osteonecrosis	0.642	0.358
M32.1 Systemic lupus erythematosus with organ or system involvement	0.642	0.358
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.639	0.361
T46 Poisoning by agents primarily affecting the cardiovascular system	0.638	0.362
S82.1 Fracture of upper end of tibia	0.638	0.362
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.637	0.362
O29 Complications of anaesthesia during pregnancy	0.637	0.363
O28 Abnormal findings on antenatal screening of mother	0.637	0.363
O22 Venous complications in pregnancy	0.637	0.363
O25 Malnutrition in pregnancy	0.637	0.363
M25.77 Osteophyte (Ankle and foot)	0.636	0.364
F20 Schizophrenia	0.636	0.364
S27.2 Traumatic heamopneumothorax	0.636	0.364
E16.9 Disorder of pancreatic internal secretion, unspecified	0.635	0.365
E16.8 Other specified disorders of pancreatic internal secretion	0.635	0.365
E16.4 Abnormal secretion of gastrin	0.635	0.365
E16.3 Increased secretion of glucagon	0.635	0.365
E16.1 Other hypoglycaemia	0.635	0.365
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.635	0.365
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.635	0.365
T41 Poisoning by anaesthetics and therapeutic gases	0.635	0.365
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.635	0.365
T36 Poisoning by systemic antibiotics	0.635	0.365
G52 Disorders of other cranial nerves	0.635	0.365
M24.01 Loose body in joint (Shoulder region)	0.634	0.366
M66.06 Rupture of popliteal cyst-Lower leg	0.634	0.366
E27.9 Disorder of adrenal gland, unspecified	0.633	0.366
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.633	0.367
M25.8 Other specified joint disorders	0.632	0.367
W22 Striking against or struck by other objects	0.632	0.368
S70 Superficial injury of hip and thigh	0.632	0.368
S80.0 Contusion of knee	0.630	0.370
S71 Open wound of hip and thigh	0.629	0.370
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.629	0.371
E50-E64 Other nutritional deficiencies	0.629	0.371
S89 Other and unspecified injuries of lower leg	0.628	0.371
S90 Superficial injury of ankle and foot	0.628	0.372
Chapter I Certain infectious and parasitic diseases	0.628	0.372
M06.0 Seronegative rheumatoid arthritis	0.627	0.373
E13 Other specified diabetes mellitus	0.626	0.373
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.626	0.373
Q35-Q37 Cleft lip and cleft palate	0.626	0.373
Q30-Q34 Congenital malformations of the respiratory system	0.626	0.373
S82.50 Fracture of medial malleolus (closed)	0.626	0.374
H73.8 Other specified disorders of tympanic membrane	0.626	0.374

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations