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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1800684
log Bayes Factor = 146.577
Chromosome 6   position 32,151,994  (GRCh37) Explore rs1800684 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
I20 Angina pectoris
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
L43 Lichen planus
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
L43.9 Lichen planus, unspecified
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.006 0.994
K51.9 Ulcerative colitis, unspecified
0.994 0.006 0.000
K51 Ulcerative colitis
0.994 0.006 0.000
I22 Subsequent myocardial infarction
0.000 0.006 0.994
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.007 0.993
E14.9 Without complications
0.000 0.007 0.993
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.009 0.991
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.012 0.988
H43-H45 Disorders of vitreous body and globe
0.000 0.012 0.988
I20.0 Unstable angina
0.000 0.013 0.987
E70-E90 Metabolic disorders
0.000 0.013 0.987
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.014 0.986
E14.3 With ophthalmic complications
0.000 0.014 0.986
H43 Disorders of vitreous body
0.000 0.016 0.984
K51.3 Ulcerative (chronic) rectosigmoiditis
0.983 0.017 0.000
I25.1 Atherosclerotic heart disease
0.000 0.020 0.980
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.023 0.977
K70-K77 Diseases of liver
0.000 0.023 0.977
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.027 0.973
I20.9 Angina pectoris, unspecified
0.000 0.030 0.970
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.032 0.968
K55-K64 Other diseases of intestines
0.000 0.033 0.967
I30-I52 Other forms of heart disease
0.000 0.034 0.966
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.036 0.964
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.037 0.963
E10.5 With peripheral circulatory complications
0.000 0.037 0.963
I47 Paroxysmal tachycardia
0.000 0.039 0.961
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.039 0.961
K60 Fissure and fistula of anal and rectal regions
0.000 0.042 0.958
K74 Fibrosis and cirrhosis of liver
0.000 0.046 0.954
H43.8 Other disorders of vitreous body
0.000 0.046 0.954
I24 Other acute ischaemic heart diseases
0.000 0.048 0.952
H43.3 Other vitreous opacities
0.000 0.049 0.951
E11.3 With ophthalmic complications
0.000 0.050 0.950
I47.1 Supraventricular tachycardia
0.000 0.054 0.946
I35 Nonrheumatic aortic valve disorders
0.000 0.055 0.945
I35.0 Aortic (valve) stenosis
0.000 0.057 0.943
J45.9 Asthma, unspecified
0.000 0.057 0.943
K60.2 Anal fissure, unspecified
0.000 0.059 0.941
I12 Hypertensive renal disease
0.000 0.059 0.941
H40-H42 Glaucoma
0.000 0.060 0.940
H34 Retinal vascular occlusions
0.000 0.061 0.939
K74.3 Primary biliary cirrhosis
0.000 0.061 0.939
K82 Other diseases of gallbladder
0.000 0.063 0.937
I21 Acute myocardial infarction
0.000 0.069 0.931
I25.5 Ischaemic cardiomyopathy
0.000 0.072 0.928
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.073 0.927
K51.8 Other ulcerative colitis
0.925 0.075 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.078 0.922
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.083 0.917
K55 Vascular disorders of intestine
0.000 0.084 0.916
E11.1 With ketoacidosis
0.000 0.085 0.915
K82.8 Other specified diseases of gallbladder
0.000 0.086 0.914
E07 Other disorders of thyroid
0.000 0.089 0.911
G37.8 Other specified demyelinating diseases of central nervous system
0.908 0.091 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.092 0.908
K63 Other diseases of intestine
0.000 0.093 0.907
K80 Cholelithiasis
0.000 0.094 0.906
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.095 0.905
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.095 0.905
I15 Secondary hypertension
0.000 0.098 0.902
I31 Other diseases of pericardium
0.000 0.100 0.900
K50-K52 Noninfective enteritis and colitis
0.025 0.101 0.874
H40.9 Glaucoma, unspecified
0.000 0.101 0.899
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.101 0.899
H40 Glaucoma
0.000 0.102 0.898
E11.2 With renal complications
0.000 0.107 0.893
K60.0 Acute anal fissure
0.000 0.108 0.892
E10.2 With renal complications
0.000 0.109 0.890
E05.9 Thyrotoxicosis, unspecified
0.000 0.110 0.890
Chapter VI Diseases of the nervous system
0.889 0.110 0.001
E13 Other specified diabetes mellitus
0.000 0.111 0.889
I20.1 Angina pectoris with documented spasm
0.000 0.116 0.884
K51.2 Ulcerative (chronic) proctitis
0.882 0.118 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.119 0.881
K55.2 Angiodysplasia of colon
0.000 0.122 0.878
I12.9 Hypertensive renal disease without renal failure
0.000 0.123 0.877
E03.8 Other specified hypothyroidism
0.000 0.127 0.873
K81 Cholecystitis
0.000 0.127 0.873
G80-G83 Cerebral palsy and other paralytic syndromes
0.872 0.127 0.000
H34.2 Other retinal artery occlusions
0.000 0.132 0.868
M06.3 Rheumatoid nodule
0.000 0.132 0.868
M07.3 Other psoriatic arthropathies
0.000 0.133 0.867
I21.9 Acute myocardial infarction, unspecified
0.000 0.135 0.865
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.136 0.864
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.137 0.863
E07.9 Disorder of thyroid, unspecified
0.000 0.138 0.862
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.138 0.862
K63.9 Disease of intestine, unspecified
0.000 0.139 0.861
K58 Irritable bowel syndrome
0.000 0.141 0.859
K75 Other inflammatory liver diseases
0.000 0.142 0.858
K72 Hepatic failure, not elsewhere classified
0.000 0.143 0.857
I31.3 Pericardial effusion (noninflammatory)
0.000 0.146 0.854
I47.2 Ventricular tachycardia
0.000 0.153 0.847
K51.5 Mucosal proctocolitis
0.847 0.153 0.000
E11.5 With peripheral circulatory complications
0.000 0.155 0.845
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.155 0.845
M06.4 Inflammatory polyarthropathy
0.000 0.157 0.843
G81 Hemiplegia
0.840 0.160 0.000
K82.1 Hydrops of gallbladder
0.000 0.166 0.834
K81.9 Cholecystitis, unspecified
0.000 0.170 0.830
I46 Cardiac arrest
0.000 0.170 0.830
K50 Crohn's disease [regional enteritis]
0.001 0.171 0.828
G30-G32 Other degenerative diseases of the nervous system
0.825 0.174 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.177 0.823
K60.5 Anorectal fistula
0.000 0.177 0.822
G81.9 Hemiplegia, unspecified
0.821 0.179 0.000
I25.2 Old myocardial infarction
0.000 0.180 0.820
K55.8 Other vascular disorders of intestine
0.000 0.182 0.818
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.184 0.816
K73 Chronic hepatitis, not elsewhere classified
0.000 0.188 0.812
E06 Thyroiditis
0.000 0.189 0.811
E13.9 Without complications
0.000 0.190 0.810
I15.1 Hypertension secondary to other renal disorders
0.000 0.190 0.810
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.191 0.809
G20-G26 Extrapyramidal and movement disorders
0.807 0.192 0.000
J45 Asthma
0.000 0.194 0.806
K63.3 Ulcer of intestine
0.000 0.197 0.803
E16.1 Other hypoglycaemia
0.000 0.198 0.802
I21.4 Acute subendocardial myocardial infarction
0.000 0.198 0.802
E11.0 With coma
0.000 0.200 0.800
G83 Other paralytic syndromes
0.800 0.200 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.799 0.201 0.000
L43.8 Other lichen planus
0.000 0.208 0.792
H43.9 Disorder of vitreous body, unspecified
0.000 0.209 0.791
E74 Other disorders of carbohydrate metabolism
0.000 0.213 0.786
G30 Alzheimer's disease
0.785 0.215 0.000
K81.1 Chronic cholecystitis
0.000 0.216 0.784
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.217 0.783
E83 Disorders of mineral metabolism
0.716 0.217 0.067
E40-E46 Malnutrition
0.000 0.219 0.781
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.222 0.778
I25.3 Aneurysm of heart
0.000 0.222 0.778
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.225 0.775
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.772
L40.8 Other psoriasis
0.000 0.228 0.772
E11.6 With other specified complications
0.000 0.228 0.772
J40-J47 Chronic lower respiratory diseases
0.000 0.230 0.770
M65-M68 Disorders of synovium and tendon
0.000 0.230 0.770
G20 Parkinson's disease
0.769 0.231 0.000
I46.9 Cardiac arrest, unspecified
0.000 0.231 0.769
Chapter X Diseases of the respiratory system
0.000 0.232 0.768
M45-M49 Spondylopathies
0.000 0.235 0.765
K51.4 Pseudopolyposis of colon
0.765 0.235 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.236 0.764
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.237 0.763
M70-M79 Other soft tissue disorders
0.000 0.238 0.762
I23 Certain current complications following acute myocardial infarction
0.000 0.239 0.761
H34.8 Other retinal vascular occlusions
0.000 0.239 0.761
E14.4 With neurological complications
0.000 0.242 0.758
M06.34 Rheumatoid nodule (Hand)
0.000 0.247 0.752
G30.9 Alzheimer's disease, unspecified
0.750 0.250 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.251 0.749
K75.4 Autoimmune hepatitis
0.000 0.253 0.747
M45 Ankylosing spondylitis
0.000 0.254 0.746
M11 Other crystal arthropathies
0.000 0.255 0.745
K51.0 Ulcerative (chronic) enterocolitis
0.745 0.255 0.000
I25.4 Coronary artery aneurysm
0.000 0.255 0.745
K74.6 Other and unspecified cirrhosis of liver
0.000 0.257 0.743
K63.2 Fistula of intestine
0.000 0.257 0.743
K50.8 Other Crohn's disease
0.000 0.263 0.737
G83.4 Cauda equina syndrome
0.737 0.263 0.000
K63.4 Enteroptosis
0.000 0.270 0.730
H30 Chorioretinal inflammation
0.000 0.270 0.730
K72.9 Hepatic failure, unspecified
0.000 0.271 0.729
E78.1 Pure hyperglyceridaemia
0.000 0.273 0.727
K50.9 Crohn's disease, unspecified
0.000 0.275 0.725
K74.5 Biliary cirrhosis, unspecified
0.000 0.278 0.722
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.280 0.720
E88 Other metabolic disorders
0.000 0.282 0.718
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.282 0.718
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
I25.6 Silent myocardial ischaemia
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.715
K90.1 Tropical sprue
0.000 0.284 0.715
L43.3 Subacute (active) lichen planus
0.000 0.284 0.715
L43.2 Lichenoid drug reaction
0.000 0.284 0.715
L43.1 Bullous lichen planus
0.000 0.284 0.715
L43.0 Hypertrophic lichen planus
0.000 0.284 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.287 0.713
M05.8 Other seropositive rheumatoid arthritis
0.000 0.287 0.713
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.287 0.713
M05.2 Rheumatoid vasculitis
0.000 0.287 0.713
M05.1 Rheumatoid lung disease
0.000 0.287 0.713
M05.0 Felty's syndrome
0.000 0.287 0.713
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.288 0.712
I51 Complications and ill-defined descriptions of heart disease
0.000 0.288 0.712
K80.8 Other cholelithiasis
0.000 0.289 0.711
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.289 0.710
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.289 0.710
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.289 0.710
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.289 0.710
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.289 0.710
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.289 0.710
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.289 0.710
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.289 0.710
Chapter VIII Diseases of the ear and mastoid process
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.291 0.709
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.707
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.292 0.707
E72 Other disorders of amino-acid metabolism
0.000 0.292 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.707
E70 Disorders of aromatic amino-acid metabolism
0.000 0.292 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.707
H43.1 Vitreous haemorrhage
0.000 0.293 0.707
M75 Shoulder lesions
0.000 0.293 0.707
H34.1 Central retinal artery occlusion
0.000 0.294 0.706
I15.9 Seconday hypertension, unspecified
0.000 0.294 0.706
H43.2 Crystalline deposits in vitreous body
0.000 0.294 0.706
H43.0 Vitreous prolapse
0.000 0.294 0.706
E78.4 Other hyperlipidaemia
0.000 0.295 0.705
M65 Synovitis and tenosynovitis
0.000 0.295 0.705
K51.1 Ulcerative (chronic) ileocolitis
0.704 0.296 0.000
I44 Atrioventricular and left bundle-branch block
0.000 0.297 0.703
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.297 0.703
K77 Liver disorders in diseases classified elsewhere
0.000 0.300 0.700
K71 Toxic liver disease
0.000 0.300 0.700
L40.0 Psoriasis vulgaris
0.000 0.301 0.699
E06.3 Autoimmune thyroiditis
0.000 0.301 0.699
M75.0 Adhesive capsulitis of shoulder
0.000 0.303 0.697
E78.2 Mixed hyperlipidaemia
0.000 0.303 0.697
K72.0 Acute and subacute hepatic failure
0.000 0.305 0.694
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.306 0.694
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.307 0.693
E11.8 With unspecified complications
0.000 0.307 0.692
I52 Other heart disorders in diseases classified elsewhere
0.000 0.308 0.692
I48 Atrial fibrillation and flutter
0.000 0.308 0.692
I41 Myocarditis in diseases classified elsewhere
0.000 0.308 0.692
I40 Acute myocarditis
0.000 0.308 0.692
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.308 0.692
I32 Pericarditis in diseases classified elsewhere
0.000 0.308 0.692
K82.9 Disease of gallbladder, unspecified
0.000 0.308 0.692
M06.0 Seronegative rheumatoid arthritis
0.000 0.309 0.691
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.309 0.691
J95-J99 Other diseases of the respiratory system
0.000 0.310 0.690
E79 Disorders of purine and pyrimidine metabolism
0.000 0.310 0.690
I31.9 Disease of pericardium, unspecified
0.000 0.311 0.689
I35.8 Other aortic valve disorders
0.000 0.311 0.689
K50.0 Crohn's disease of small intestine
0.000 0.313 0.687
I11 Hypertensive heart disease
0.000 0.313 0.687
K55.1 Chronic vascular disorders of intestine
0.000 0.314 0.686
E78.8 Other disorders of lipoprotein metabolism
0.000 0.315 0.685
K74.4 Secondary biliary cirrhosis
0.000 0.316 0.684
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.316 0.684
K74.1 Hepatic sclerosis
0.000 0.316 0.684
I51.8 Other ill-defined heart diseases
0.000 0.316 0.684
K75.0 Abscess of liver
0.000 0.317 0.683
J46 Status asthmaticus
0.000 0.320 0.680
K82.3 Fistula of gallbladder
0.000 0.321 0.679
L42 Pityriasis rosea
0.000 0.321 0.679
I30 Acute pericarditis
0.000 0.322 0.678
K82.2 Perforation of gallbladder
0.000 0.322 0.678
E83.3 Disorders of phosphorus metabolism
0.659 0.323 0.018
H42 Glaucoma in diseases classified elsewhere
0.000 0.326 0.674
H34.9 Retinal vascular occlusion, unspecified
0.000 0.326 0.674
H34.0 Transient retinal artery occlusion
0.000 0.326 0.674
Q60-Q64 Congenital malformations of the urinary system
0.000 0.327 0.673
J86 Pyothorax
0.000 0.328 0.672
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.329 0.671
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.331 0.669
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.333 0.667
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.333 0.667
M14 Arthropathies in other diseases classified elsewhere
0.000 0.336 0.664
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.336 0.664
K90.9 Intestinal malabsorption, unspecified
0.000 0.336 0.664
M07.6 Other enteropathic arthropathies
0.000 0.339 0.661
M07.5 Arthropathy in ulcerative colitis
0.000 0.339 0.661
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.339 0.661
M07.2 Psoriatic spondylitis
0.000 0.339 0.661
M07.1 Arthritis mutilans
0.000 0.339 0.661
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.339 0.661
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.339 0.660
Q61 Cystic kidney disease
0.000 0.341 0.659
H40.4 Glaucoma secondary to eye inflammation
0.000 0.341 0.659
K73.9 Chronic hepatitis, unspecified
0.000 0.343 0.657
E05.5 Thyroid crisis or storm
0.000 0.343 0.657
E05.4 Thyrotoxicosis factitia
0.000 0.343 0.657
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.343 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.343 0.657
E84 Cystic fibrosis
0.000 0.344 0.656
G83.1 Monoplegia of lower limb
0.656 0.344 0.000
H60-H62 Diseases of external ear
0.000 0.345 0.655
M12 Other specific arthropathies
0.000 0.346 0.654
E07.1 Dyshormogenetic goitre
0.000 0.346 0.653
E07.0 Hypersecretion of calcitonin
0.000 0.346 0.653
K80.3 Calculus of bile duct with cholangitis
0.000 0.350 0.650
I05-I09 Chronic rheumatic heart diseases
0.000 0.351 0.649
I15.8 Other secondary hypertension
0.000 0.353 0.646
I15.2 Hypertension secondary to endocrine disorders
0.000 0.353 0.646
I15.0 Renovascular hypertension
0.000 0.353 0.646
M86-M90 Other osteopathies
0.000 0.354 0.646
I31.8 Other specified diseases of pericardium
0.000 0.355 0.645
I31.2 Haemopericardium, not elsewhere classified
0.000 0.355 0.645
I31.0 Chronic adhesive pericarditis
0.000 0.355 0.645
I44.3 Other and unspecified atrioventricular block
0.000 0.355 0.645
H40.6 Glaucoma secondary to drugs
0.000 0.356 0.644
H40.3 Glaucoma secondary to eye trauma
0.000 0.356 0.644
M77 Other enthesopathies
0.000 0.356 0.644
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.357 0.643
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.641
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.362 0.638
E13.8 With unspecified complications
0.000 0.362 0.638
E13.7 With multiple complications
0.000 0.362 0.638
E13.6 With other specified complications
0.000 0.362 0.638
E13.5 With peripheral circulatory complications
0.000 0.362 0.638
E13.4 With neurological complications
0.000 0.362 0.638
E13.3 With ophthalmic complications
0.000 0.362 0.638
E13.2 With renal complications
0.000 0.362 0.638
E13.1 With ketoacidosis
0.000 0.362 0.638
E13.0 With coma
0.000 0.362 0.638
K90.8 Other intestinal malabsorption
0.000 0.365 0.635
K60.4 Rectal fistula
0.000 0.365 0.635
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.366 0.633
K82.0 Obstruction of gallbladder
0.000 0.367 0.633
E89.3 Postprocedural hypopituitarism
0.000 0.370 0.630
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.371 0.629
G83.9 Paralytic syndrome, unspecified
0.629 0.371 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.371 0.628
Q50-Q56 Congenital malformations of genital organs
0.000 0.373 0.627
M75.2 Bicipital tendinitis
0.000 0.374 0.626
E46 Unspecified protein-energy malnutrition
0.000 0.375 0.625
J98 Other respiratory disorders
0.000 0.376 0.624
I36 Nonrheumatic tricuspid valve disorders
0.000 0.376 0.624
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.378 0.622
M06.38 Rheumatoid nodule (Other)
0.000 0.378 0.622
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.378 0.622
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.378 0.622
M06.33 Rheumatoid nodule (Forearm)
0.000 0.378 0.622
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.378 0.622
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.378 0.622
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.378 0.622
K75.9 Inflammatory liver disease, unspecified
0.000 0.378 0.622
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.621 0.378 0.001
M07.38 Other psoriatic arthropathies (Other)
0.000 0.379 0.621
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.379 0.621
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.379 0.621
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.379 0.621
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.379 0.621
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.379 0.621
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.379 0.621
K63.8 Other specified diseases of intestine
0.000 0.381 0.619
G00-G09 Inflammatory diseases of the central nervous system
0.618 0.382 0.000
K63.0 Abscess of intestine
0.000 0.382 0.617
G80 Infantile cerebral palsy
0.617 0.383 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.383 0.616
I24.1 Dressler's syndrome
0.000 0.384 0.616
H65-H75 Diseases of middle ear and mastoid
0.000 0.384 0.616
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.385 0.615
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.385 0.615
K75.2 Nonspecific reactive hepatitis
0.000 0.385 0.615
K75.1 Phlebitis of portal vein
0.000 0.385 0.615
E83.9 Disorder of mineral metabolism, unspecified
0.574 0.386 0.041
K72.1 Chronic hepatic failure
0.000 0.386 0.614
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.386 0.614
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.387 0.613
E11.4 With neurological complications
0.000 0.388 0.611
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.391 0.609
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.608 0.392 0.000
M77.1 Lateral epicondylitis
0.000 0.395 0.605
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.395 0.605
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.395 0.605
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.395 0.605
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.395 0.605
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.395 0.605
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.395 0.605
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.395 0.605
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.395 0.605
G81.0 Flaccid hemiplegia
0.603 0.397 0.000
K60.1 Chronic anal fissure
0.000 0.397 0.602
J86.9 Pyothorax without fistula
0.000 0.398 0.602
E73 Lactose intolerance
0.000 0.399 0.601
G30.8 Other Alzheimer's disease
0.601 0.399 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.400 0.600
H40.1 Primary open-angle glaucoma
0.000 0.401 0.599
G25 Other extrapyramidal and movement disorders
0.599 0.401 0.000
J43 Emphysema
0.000 0.402 0.598
Q61.3 Polycystic kidney, unspecified
0.000 0.403 0.597
I46.1 Sudden cardiac death, so described
0.000 0.405 0.595
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.406 0.594
Q61.0 Congenital single renal cyst
0.000 0.408 0.592
M10 Gout
0.000 0.409 0.591
I23.8 Other current complications following acute myocardial infarction
0.000 0.410 0.590
K75.8 Other specified inflammatory liver diseases
0.000 0.411 0.589
I37 Pulmonary valve disorders
0.000 0.411 0.588
M88 Paget's disease of bone [osteitis deformans]
0.000 0.412 0.588
I31.1 Chronic constrictive pericarditis
0.000 0.415 0.585
K65-K67 Diseases of peritoneum
0.000 0.416 0.584
H71 Cholesteatoma of middle ear
0.000 0.417 0.583
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.417 0.582
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.417 0.582
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.417 0.582
J86.0 Pyothorax with fistula
0.000 0.417 0.582
Q61.2 Polycystic kidney, adult type
0.000 0.418 0.582
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.418 0.582
E06.5 Other chronic thyroiditis
0.000 0.419 0.581
E06.4 Drug-induced thyroiditis
0.000 0.419 0.581
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.419 0.581
E06.1 Subacute thyroiditis
0.000 0.419 0.581
E06.0 Acute thyroiditis
0.000 0.419 0.581

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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