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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181319480
log Bayes Factor = 9.5655
Chromosome 3   position 58,793,057  (GRCh37) Explore rs181319480 on Ensembl!
Variant rs181319480 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C50 Malignant neoplasm of breast
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
C50-C50 Malignant neoplasm of breast
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
C50.4 Upper-outer quadrant of breast
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.986 0.014 0.000
I05-I09 Chronic rheumatic heart diseases
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.976 0.024 0.000
F30-F39 Mood [affective] disorders
0.976 0.024 0.000
M05-M14 Inflammatory polyarthropathies
0.973 0.027 0.000
I08 Multiple valve diseases
0.967 0.033 0.000
Chapter VII Diseases of the eye and adnexa
0.963 0.037 0.000
M13 Other arthritis
0.951 0.049 0.000
I08.0 Disorders of both mitral and aortic valves
0.948 0.052 0.000
Chapter I Certain infectious and parasitic diseases
0.940 0.060 0.000
M13.9 Arthritis, unspecified
0.935 0.065 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.935 0.065 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
A30-A49 Other bacterial diseases
0.933 0.067 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.930 0.070 0.000
F32 Depressive episode
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.929 0.071 0.000
C50.9 Breast, unspecified
0.926 0.074 0.000
A41 Other septicaemia
0.922 0.078 0.000
S80-S89 Injuries to the knee and lower leg
0.915 0.085 0.000
T66-T78 Other and unspecified effects of external causes
0.915 0.085 0.000
I47 Paroxysmal tachycardia
0.913 0.087 0.000
M06 Other rheumatoid arthritis
0.912 0.088 0.000
C50.2 Upper-inner quadrant of breast
0.911 0.089 0.000
T39.0 Salicylates
0.908 0.092 0.000
I35 Nonrheumatic aortic valve disorders
0.908 0.092 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.904 0.096 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.901 0.099 0.000
A41.9 Septicaemia, unspecified
0.901 0.099 0.000
R50-R69 General symptoms and signs
0.898 0.102 0.000
R53 Malaise and fatigue
0.895 0.105 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.894 0.106 0.000
F33 Recurrent depressive disorder
0.893 0.107 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.893 0.107 0.000
T39.1 4-Aminophenol derivatives
0.886 0.114 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.885 0.115 0.000
M86-M90 Other osteopathies
0.865 0.135 0.000
I49 Other cardiac arrhythmias
0.862 0.138 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.857 0.143 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.855 0.145 0.000
T78 Adverse effects, not elsewhere classified
0.853 0.147 0.000
T43.2 Other and unspecified antidepressants
0.853 0.147 0.000
F60-F69 Disorders of adult personality and behaviour
0.851 0.149 0.000
R55 Syncope and collapse
0.850 0.150 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.848 0.152 0.000
Chapter VIII Diseases of the ear and mastoid process
0.846 0.154 0.000
S90-S99 Injuries to the ankle and foot
0.846 0.154 0.000
S50-S59 Injuries to the elbow and forearm
0.842 0.158 0.000
M06.9 Rheumatoid arthritis, unspecified
0.841 0.159 0.000
I47.1 Supraventricular tachycardia
0.840 0.160 0.000
M05 Seropositive rheumatoid arthritis
0.840 0.160 0.000
F32.1 Moderate depressive episode
0.834 0.166 0.000
I45 Other conduction disorders
0.833 0.167 0.000
C50.1 Central portion of breast
0.831 0.169 0.000
C50.8 Overlapping lesion of breast
0.825 0.175 0.000
L60-L75 Disorders of skin appendages
0.825 0.175 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.819 0.181 0.000
H55-H59 Other disorders of eye and adnexa
0.818 0.182 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.816 0.184 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.815 0.185 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.813 0.187 0.000
S40-S49 Injuries to the shoulder and upper arm
0.813 0.187 0.000
I51 Complications and ill-defined descriptions of heart disease
0.811 0.189 0.000
H10-H13 Disorders of conjunctiva
0.808 0.192 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.808 0.192 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.805 0.195 0.000
I33 Acute and subacute endocarditis
0.804 0.196 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.804 0.196 0.000
F80-F89 Disorders of psychological development
0.802 0.198 0.000
M07 Psoriatic and enteropathic arthropathies
0.799 0.201 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.798 0.202 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.796 0.204 0.000
A49 Bacterial infection of unspecified site
0.795 0.205 0.000
T78.4 Allergy, unspecified
0.795 0.205 0.000
V98-V99 Other and unspecified transport accidents
0.793 0.207 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.792 0.208 0.000
S70-S79 Injuries to the hip and thigh
0.792 0.208 0.000
I42 Cardiomyopathy
0.790 0.210 0.000
F33.9 Recurrent depressive disorder, unspecified
0.789 0.211 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.789 0.211 0.000
C50.5 Lower-outer quadrant of breast
0.788 0.212 0.000
F03 Unspecified dementia
0.787 0.213 0.000
I44 Atrioventricular and left bundle-branch block
0.787 0.213 0.000
V10-V19 Pedal cyclist injured in transport accident
0.787 0.213 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.785 0.215 0.000
A41.8 Other specified septicaemia
0.783 0.217 0.000
H30-H36 Disorders of choroid and retina
0.781 0.219 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.781 0.219 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.779 0.221 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.778 0.222 0.000
F30 Manic episode
0.778 0.222 0.000
C15-C26 Malignant neoplasms of digestive organs
0.777 0.223 0.000
L50-L54 Urticaria and erythema
0.776 0.224 0.000
I35.0 Aortic (valve) stenosis
0.776 0.224 0.000
L60 Nail disorders
0.773 0.227 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.772 0.228 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.771 0.229 0.000
Q80-Q89 Other congenital malformations
0.768 0.231 0.000
I35.1 Aortic (valve) insufficiency
0.768 0.231 0.000
M89 Other disorders of bone
0.768 0.232 0.000
H40-H42 Glaucoma
0.768 0.232 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.767 0.233 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.767 0.233 0.000
C50.0 Nipple and areola
0.767 0.233 0.000
I51.8 Other ill-defined heart diseases
0.766 0.234 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.766 0.234 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.764 0.236 0.000
S51 Open wound of forearm
0.763 0.237 0.000
R51 Headache
0.762 0.238 0.000
S80 Superficial injury of lower leg
0.761 0.239 0.000
Y40 Systemic antibiotics
0.759 0.241 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.758 0.242 0.000
I05 Rheumatic mitral valve diseases
0.758 0.242 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.758 0.242 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.758 0.242 0.000
M65-M68 Disorders of synovium and tendon
0.756 0.244 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.755 0.245 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
T51 Toxic effect of alcohol
0.755 0.245 0.000
W20-W49 Exposure to inanimate mechanical forces
0.755 0.245 0.000
M06.0 Seronegative rheumatoid arthritis
0.754 0.246 0.000
I77 Other disorders of arteries and arterioles
0.753 0.247 0.000
M13.98 Arthritis, unspecified (Other)
0.752 0.248 0.000
Y44 Agents primarily affecting blood constituents
0.752 0.248 0.000
I35.8 Other aortic valve disorders
0.750 0.250 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.749 0.250 0.000
F60 Specific personality disorders
0.748 0.252 0.000
I38 Endocarditis, valve unspecified
0.746 0.254 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.744 0.256 0.000
I46 Cardiac arrest
0.744 0.256 0.000
C50.3 Lower-inner quadrant of breast
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.742 0.258 0.000
Chapter XXII Codes for special purposes
0.741 0.258 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.741 0.259 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.740 0.260 0.000
T42.4 Benzodiazepines
0.738 0.262 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.734 0.266 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.734 0.266 0.000
Q00-Q07 Congenital malformations of the nervous system
0.733 0.267 0.000
M60-M63 Disorders of muscles
0.733 0.267 0.000
R59 Enlarged lymph nodes
0.733 0.267 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.731 0.269 0.000
I49.3 Ventricular premature depolarisation
0.731 0.269 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.730 0.270 0.000
V40-V49 Car occupant injured in transport accident
0.730 0.270 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.727 0.273 0.000
D00-D09 In situ neoplasms
0.724 0.276 0.000
H34 Retinal vascular occlusions
0.723 0.277 0.000
I30 Acute pericarditis
0.723 0.277 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.723 0.277 0.000
Y52 Agents primarily affecting the cardiovascular system
0.723 0.277 0.000
B65-B83 Helminthiases
0.722 0.278 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
I72 Other aneurysm
0.721 0.279 0.000
S92 Fracture of foot, except ankle
0.720 0.280 0.000
I74 Arterial embolism and thrombosis
0.720 0.280 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.719 0.281 0.000
W00-W19 Falls
0.719 0.281 0.000
V20-V29 Motorcycle rider injured in transport accident
0.719 0.281 0.000
H65-H75 Diseases of middle ear and mastoid
0.718 0.282 0.000
H00 Hordeolum and chalazion
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C50.6 Axillary tail of breast
0.715 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
I47.2 Ventricular tachycardia
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
Chapter VI Diseases of the nervous system
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.713 0.287 0.000
S86 Injury of muscle and tendon at lower leg level
0.712 0.288 0.000
I45.1 Other and unspecified right bundle-branch block
0.712 0.288 0.000
T78.2 Anaphylactic shock, unspecified
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
L20-L30 Dermatitis and eczema
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.289 0.000
I48 Atrial fibrillation and flutter
0.711 0.289 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.289 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.289 0.000
I40 Acute myocarditis
0.711 0.289 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.289 0.000
I37 Pulmonary valve disorders
0.711 0.289 0.000
I36 Nonrheumatic tricuspid valve disorders
0.711 0.289 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.289 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.709 0.291 0.000
L73 Other follicular disorders
0.709 0.291 0.000
I73 Other peripheral vascular diseases
0.708 0.292 0.000
C64-C68 Malignant neoplasms of urinary tract
0.708 0.292 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.707 0.293 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.707 0.293 0.000
T39.4 Antirheumatics, not elsewhere classified
0.707 0.293 0.000
T39.2 Pyrazolone derivatives
0.707 0.293 0.000
S40 Superficial injury of shoulder and upper arm
0.706 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
I09 Other rheumatic heart diseases
0.703 0.297 0.000
I06 Rheumatic aortic valve diseases
0.703 0.297 0.000
M40-M43 Deforming dorsopathies
0.702 0.298 0.000
M91-M94 Chondropathies
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
F38 Other mood [affective] disorders
0.700 0.300 0.000
F34 Persistent mood [affective] disorders
0.700 0.300 0.000
F39 Unspecified mood [affective] disorder
0.700 0.300 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.698 0.301 0.000
M14 Arthropathies in other diseases classified elsewhere
0.698 0.302 0.000
M12 Other specific arthropathies
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.698 0.302 0.000
M08 Juvenile arthritis
0.698 0.302 0.000
M89.9 Disorder of bone, unspecified
0.697 0.303 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.695 0.305 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.695 0.305 0.000
I07 Rheumatic tricuspid valve diseases
0.695 0.305 0.000
I08.9 Multiple valve disease, unspecified
0.693 0.307 0.000
I08.8 Other multiple valve diseases
0.693 0.307 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.693 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
F01 Vascular dementia
0.693 0.307 0.000
F00 Dementia in Alzheimer's disease
0.693 0.307 0.000
M13.93 Arthritis, unspecified (Forearm)
0.692 0.307 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.691 0.309 0.000
L60.0 Ingrowing nail
0.691 0.309 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.690 0.310 0.000
H60-H62 Diseases of external ear
0.688 0.312 0.000
H11 Other disorders of conjunctiva
0.688 0.312 0.000
M13.0 Polyarthritis, unspecified
0.686 0.314 0.000
S20-S29 Injuries to the thorax
0.685 0.315 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.685 0.315 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.684 0.316 0.000
H57 Other disorders of eye and adnexa
0.684 0.316 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
M13.8 Other specified arthritis
0.682 0.318 0.000
M13.1 Monoarthritis, not elsewhere classified
0.682 0.318 0.000
S82 Fracture of lower leg, including ankle
0.681 0.319 0.000
I49.9 Cardiac arrhythmia, unspecified
0.680 0.320 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.679 0.321 0.000
F32.0 Mild depressive episode
0.679 0.321 0.000
I27 Other pulmonary heart diseases
0.676 0.324 0.000
B15-B19 Viral hepatitis
0.675 0.325 0.000
S81 Open wound of lower leg
0.675 0.325 0.000
B99-B99 Other infectious diseases
0.674 0.326 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.326 0.000
B50-B64 Protozoal diseases
0.674 0.326 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.674 0.326 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.326 0.000
A80-A89 Viral infections of the central nervous system
0.674 0.326 0.000
A75-A79 Rickettsioses
0.674 0.326 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.326 0.000
A65-A69 Other spirochaetal diseases
0.674 0.326 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.326 0.000
A15-A19 Tuberculosis
0.674 0.326 0.000
M07.3 Other psoriatic arthropathies
0.674 0.326 0.000
S51.9 Open wound of forearm, part unspecified
0.674 0.326 0.000
L40-L45 Papulosquamous disorders
0.673 0.327 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.672 0.328 0.000
H34.8 Other retinal vascular occlusions
0.672 0.328 0.000
Q21 Congenital malformations of cardiac septa
0.672 0.328 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.671 0.329 0.000
L10-L14 Bullous disorders
0.671 0.329 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.670 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.670 0.330 0.000
I33.0 Acute and subacute infective endocarditis
0.670 0.330 0.000
Q50-Q56 Congenital malformations of genital organs
0.669 0.330 0.000
A48 Other bacterial diseases, not elsewhere classified
0.669 0.331 0.000
A44 Bartonellosis
0.669 0.331 0.000
A43 Nocardiosis
0.669 0.331 0.000
A42 Actinomycosis
0.669 0.331 0.000
A40 Streptococcal septicaemia
0.669 0.331 0.000
A39 Meningococcal infection
0.669 0.331 0.000
A37 Whooping cough
0.669 0.331 0.000
A36 Diphtheria
0.669 0.331 0.000
A32 Listeriosis
0.669 0.331 0.000
A31 Infection due to other mycobacteria
0.669 0.331 0.000
A30 Leprosy [Hansen's disease]
0.669 0.331 0.000
A46 Erysipelas
0.669 0.331 0.000
A38 Scarlet fever
0.669 0.331 0.000
A35 Other tetanus
0.669 0.331 0.000
A34 Obstetrical tetanus
0.669 0.331 0.000
A33 Tetanus neonatorum
0.669 0.331 0.000
M87 Osteonecrosis
0.669 0.331 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
F32.8 Other depressive episodes
0.666 0.334 0.000
H46 Optic neuritis
0.666 0.334 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.666 0.334 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.666 0.334 0.000
Q35-Q37 Cleft lip and cleft palate
0.666 0.334 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.666 0.334 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
F81 Specific developmental disorders of scholastic skills
0.664 0.336 0.000
I49.4 Other and unspecified premature depolarisation
0.664 0.336 0.000
D45 Polycythaemia vera
0.664 0.336 0.000
R57 Shock, not elsewhere classified
0.663 0.337 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.663 0.337 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.663 0.337 0.000
I78 Diseases of capillaries
0.662 0.337 0.000
I35.9 Aortic valve disorder, unspecified
0.662 0.338 0.000
L50 Urticaria
0.662 0.338 0.000
A41.4 Septicaemia due to anaerobes
0.661 0.339 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.661 0.339 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.661 0.339 0.000
V99 Unspecified transport accident
0.661 0.339 0.000
I44.1 Atrioventricular block, second degree
0.661 0.339 0.000
I31 Other diseases of pericardium
0.660 0.340 0.000
S50 Superficial injury of forearm
0.660 0.340 0.000
S60-S69 Injuries to the wrist and hand
0.660 0.340 0.000
T51.0 Ethanol
0.659 0.341 0.000
T79-T79 Certain early complications of trauma
0.658 0.341 0.000
H43-H45 Disorders of vitreous body and globe
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.656 0.343 0.000
S88 Traumatic amputation of lower leg
0.656 0.344 0.000
S87 Crushing injury of lower leg
0.656 0.344 0.000
S85 Injury of blood vessels at lower leg level
0.656 0.344 0.000
S84 Injury of nerves at lower leg level
0.656 0.344 0.000
T75 Effects of other external causes
0.656 0.344 0.000
T74 Maltreatment syndromes
0.656 0.344 0.000
T73 Effects of other deprivation
0.656 0.344 0.000
T70 Effects of air pressure and water pressure
0.656 0.344 0.000
T69 Other effects of reduced temperature
0.656 0.344 0.000
T67 Effects of heat and light
0.656 0.344 0.000
T71 Asphyxiation
0.656 0.344 0.000
T68 Hypothermia
0.656 0.344 0.000
T66 Unspecified effects of radiation
0.656 0.344 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.655 0.345 0.000
I47.0 Reentry ventricular arrhythmia
0.655 0.345 0.000
M06.8 Other specified rheumatoid arthritis
0.654 0.346 0.000
M06.4 Inflammatory polyarthropathy
0.654 0.346 0.000
M06.3 Rheumatoid nodule
0.654 0.346 0.000
M06.2 Rheumatoid bursitis
0.654 0.346 0.000
M06.1 Adult-onset Still's disease
0.654 0.346 0.000
R59.0 Localised enlarged lymph nodes
0.654 0.346 0.000
R60 Oedema, not elsewhere classified
0.654 0.346 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.652 0.348 0.000
M11 Other crystal arthropathies
0.652 0.348 0.000
C71 Malignant neoplasm of brain
0.651 0.349 0.000
A49.0 Staphylococcal infection, unspecified
0.651 0.349 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.651 0.349 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.650 0.350 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.650 0.350 0.000
M70-M79 Other soft tissue disorders
0.649 0.351 0.000
M80-M85 Disorders of bone density and structure
0.649 0.351 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.648 0.351 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.647 0.353 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.647 0.353 0.000
R00 Abnormalities of heart beat
0.647 0.353 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.647 0.353 0.000
S00-S09 Injuries to the head
0.647 0.353 0.000
Q24 Other congenital malformations of heart
0.647 0.353 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.647 0.353 0.000
F60.3 Emotionally unstable personality disorder
0.647 0.353 0.000
T43.9 Psychotropic drug, unspecified
0.646 0.354 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
T43.6 Psychostimulants with abuse potential
0.646 0.354 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.646 0.354 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.646 0.354 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.646 0.354 0.000
S99 Other and unspecified injuries of ankle and foot
0.645 0.355 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.645 0.355 0.000
H90-H95 Other disorders of ear
0.644 0.356 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.644 0.356 0.000
R62 Lack of expected normal physiological development
0.644 0.356 0.000
R64 Cachexia
0.644 0.356 0.000
R58 Haemorrhage, not elsewhere classified
0.644 0.356 0.000
I49.8 Other specified cardiac arrhythmias
0.644 0.356 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.643 0.357 0.000
M88 Paget's disease of bone [osteitis deformans]
0.642 0.358 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.641 0.359 0.000
F33.8 Other recurrent depressive disorders
0.641 0.359 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.641 0.359 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.641 0.359 0.000
A49.8 Other bacterial infections of unspecified site
0.640 0.360 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.640 0.360 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.640 0.360 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.640 0.360 0.000
T42.3 Barbiturates
0.640 0.360 0.000
T42.2 Succinimides and oxazolidinediones
0.640 0.360 0.000
T42.1 Iminostilbenes
0.640 0.360 0.000
T42.0 Hydantoin derivatives
0.640 0.360 0.000
R30-R39 Symptoms and signs involving the urinary system
0.640 0.360 0.000
L60.9 Nail disorder, unspecified
0.639 0.361 0.000
R94 Abnormal results of function studies
0.639 0.361 0.000
I45.5 Other specified heart block
0.639 0.361 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.639 0.361 0.000
I42.8 Other cardiomyopathies
0.638 0.362 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.637 0.363 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.636 0.363 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.636 0.364 0.000
F30.9 Manic episode, unspecified
0.636 0.364 0.000
I51.6 Cardiovascular disease, unspecified
0.635 0.364 0.000
M65 Synovitis and tenosynovitis
0.635 0.365 0.000
S89 Other and unspecified injuries of lower leg
0.635 0.365 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.635 0.365 0.000
F02 Dementia in other diseases classified elsewhere
0.635 0.365 0.000
F09 Unspecified organic or symptomatic mental disorder
0.635 0.365 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.635 0.365 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.634 0.366 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.633 0.367 0.000
S72 Fracture of femur
0.633 0.367 0.000
H25-H28 Disorders of lens
0.632 0.368 0.000
I49.1 Atrial premature depolarisation
0.630 0.370 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.630 0.370 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.629 0.370 0.000
C60-C63 Malignant neoplasms of male genital organs
0.629 0.371 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.628 0.372 0.000
H40 Glaucoma
0.628 0.372 0.000
I42.6 Alcoholic cardiomyopathy
0.627 0.373 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.627 0.373 0.000
F31 Bipolar affective disorder
0.626 0.374 0.000
R54 Senility
0.626 0.374 0.000
S51.0 Open wound of elbow
0.626 0.374 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.626 0.374 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.625 0.375 0.000
S80.9 Superficial injury of lower leg, unspecified
0.625 0.375 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.623 0.377 0.000
B25-B34 Other viral diseases
0.623 0.377 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.623 0.377 0.000
S92.3 Fracture of metatarsal bone
0.622 0.378 0.000
R32 Unspecified urinary incontinence
0.622 0.378 0.000
R00.1 Bradycardia, unspecified
0.621 0.379 0.000
M90 Osteopathies in diseases classified elsewhere
0.620 0.379 0.000
Y44.2 Anticoagulants
0.620 0.380 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.619 0.381 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.618 0.382 0.000
I05.2 Mitral stenosis with insufficiency
0.618 0.382 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.618 0.382 0.000
I49.2 Junctional premature depolarisation
0.618 0.382 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.617 0.383 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.616 0.383 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.616 0.384 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.616 0.384 0.000
C78.0 Secondary malignant neoplasm of lung
0.616 0.384 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.616 0.384 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.615 0.385 0.000
T65 Toxic effect of other and unspecified substances
0.614 0.385 0.000
T63 Toxic effect of contact with venomous animals
0.614 0.385 0.000
T62 Toxic effect of other noxious substances eaten as food
0.614 0.385 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.614 0.385 0.000
T60 Toxic effect of pesticides
0.614 0.385 0.000
T59 Toxic effect of other gases, fumes and vapours
0.614 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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