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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181704351
log Bayes Factor = 8.19928
Chromosome 1   position 70,147,866  (GRCh37) Explore rs181704351 on Ensembl!
Variant rs181704351 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.977 0.023 0.000
J20-J22 Other acute lower respiratory infections
0.977 0.023 0.000
R63 Symptoms and signs concerning food and fluid intake
0.974 0.026 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.963 0.037 0.000
J22 Unspecified acute lower respiratory infection
0.960 0.040 0.000
Chapter V Mental and behavioural disorders
0.953 0.047 0.000
J90-J94 Other diseases of pleura
0.951 0.049 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.948 0.052 0.000
R51 Headache
0.943 0.057 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.939 0.061 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
R69 Unknown and unspecified causes of morbidity
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
R63.4 Abnormal weight loss
0.922 0.078 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.916 0.084 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.916 0.084 0.000
R53 Malaise and fatigue
0.913 0.087 0.000
J90 Pleural effusion, not elsewhere classified
0.903 0.097 0.000
J40-J47 Chronic lower respiratory diseases
0.899 0.101 0.000
M20-M25 Other joint disorders
0.894 0.106 0.000
R63.0 Anorexia
0.879 0.121 0.000
Chapter IX Diseases of the circulatory system
0.874 0.126 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.870 0.130 0.000
D70 Agranulocytosis
0.869 0.131 0.000
Chapter XIV Diseases of the genitourinary system
0.868 0.132 0.000
J00-J06 Acute upper respiratory infections
0.866 0.134 0.000
B95-B98 Bacterial, viral and other infectious agents
0.865 0.135 0.000
R59 Enlarged lymph nodes
0.855 0.145 0.000
Chapter XI Diseases of the digestive system
0.855 0.145 0.000
J09-J18 Influenza and pneumonia
0.853 0.147 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.853 0.147 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.849 0.151 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.845 0.155 0.000
Chapter VIII Diseases of the ear and mastoid process
0.843 0.157 0.000
N40-N51 Diseases of male genital organs
0.841 0.159 0.000
M23 Internal derangement of knee
0.837 0.163 0.000
J47 Bronchiectasis
0.837 0.163 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.836 0.164 0.000
K55-K64 Other diseases of intestines
0.835 0.165 0.000
F30-F39 Mood [affective] disorders
0.834 0.166 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.825 0.174 0.000
R94 Abnormal results of function studies
0.821 0.179 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.820 0.180 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.817 0.183 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.816 0.184 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.814 0.186 0.000
K63 Other diseases of intestine
0.812 0.188 0.000
D60-D64 Aplastic and other anaemias
0.803 0.197 0.000
K59 Other functional intestinal disorders
0.800 0.200 0.000
I30-I52 Other forms of heart disease
0.794 0.206 0.000
D69 Purpura and other haemorrhagic conditions
0.793 0.207 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.791 0.209 0.000
K63.5 Polyp of colon
0.790 0.210 0.000
R79 Other abnormal findings of blood chemistry
0.787 0.213 0.000
S60-S69 Injuries to the wrist and hand
0.783 0.217 0.000
M25 Other joint disorders, not elsewhere classified
0.780 0.220 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.769 0.231 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.768 0.232 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.766 0.234 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.764 0.236 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.762 0.238 0.000
K59.0 Constipation
0.760 0.240 0.000
Chapter II Neoplasms
0.759 0.241 0.000
F31 Bipolar affective disorder
0.759 0.241 0.000
R47-R49 Symptoms and signs involving speech and voice
0.758 0.242 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.758 0.242 0.000
R60 Oedema, not elsewhere classified
0.757 0.243 0.000
J40 Bronchitis, not specified as acute or chronic
0.756 0.244 0.000
R06 Abnormalities of breathing
0.749 0.251 0.000
Y43 Primarily systemic agents
0.746 0.254 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.746 0.254 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.745 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.744 0.255 0.000
J92 Pleural plaque
0.744 0.256 0.000
M23.3 Other meniscus derangements
0.744 0.256 0.000
L50-L54 Urticaria and erythema
0.743 0.257 0.000
J30-J39 Other diseases of upper respiratory tract
0.741 0.259 0.000
D69.6 Thrombocytopenia, unspecified
0.738 0.261 0.000
M45-M49 Spondylopathies
0.736 0.264 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.735 0.265 0.000
N48 Other disorders of penis
0.733 0.267 0.000
Y95 Nosocomial condition
0.733 0.267 0.000
N60-N64 Disorders of breast
0.732 0.268 0.000
R94.5 Abnormal results of liver function studies
0.730 0.270 0.000
L20-L30 Dermatitis and eczema
0.727 0.273 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.725 0.275 0.000
N40 Hyperplasia of prostate
0.723 0.277 0.000
L08 Other local infections of skin and subcutaneous tissue
0.722 0.278 0.000
S40-S49 Injuries to the shoulder and upper arm
0.722 0.278 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
M65-M68 Disorders of synovium and tendon
0.718 0.281 0.000
B25-B34 Other viral diseases
0.718 0.282 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.718 0.282 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.717 0.282 0.000
R90.0 Intracranial space-occupying lesion
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
R68 Other general symptoms and signs
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R57 Shock, not elsewhere classified
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
R54 Senility
0.716 0.284 0.000
R61 Hyperhidrosis
0.715 0.285 0.000
M86-M90 Other osteopathies
0.714 0.286 0.000
H90-H95 Other disorders of ear
0.714 0.286 0.000
R73 Elevated blood glucose level
0.712 0.288 0.000
R06.0 Dyspnoea
0.712 0.288 0.000
J60-J70 Lung diseases due to external agents
0.711 0.288 0.000
J18 Pneumonia, organism unspecified
0.711 0.289 0.000
F03 Unspecified dementia
0.711 0.289 0.000
A30-A49 Other bacterial diseases
0.711 0.289 0.000
S80-S89 Injuries to the knee and lower leg
0.709 0.291 0.000
L40-L45 Papulosquamous disorders
0.708 0.291 0.000
I51 Complications and ill-defined descriptions of heart disease
0.708 0.292 0.000
R52 Pain, not elsewhere classified
0.706 0.293 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.706 0.294 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.705 0.295 0.000
L03 Cellulitis
0.703 0.297 0.000
M40-M43 Deforming dorsopathies
0.703 0.297 0.000
D80-D89 Certain disorders involving the immune mechanism
0.700 0.300 0.000
D55-D59 Haemolytic anaemias
0.700 0.300 0.000
J21 Acute bronchiolitis
0.700 0.300 0.000
J20 Acute bronchitis
0.700 0.300 0.000
J93 Pneumothorax
0.699 0.301 0.000
S00-S09 Injuries to the head
0.699 0.301 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.698 0.302 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.698 0.302 0.000
R63.5 Abnormal weight gain
0.698 0.302 0.000
R63.3 Feeding difficulties and mismanagement
0.698 0.302 0.000
R63.2 Polyphagia
0.698 0.302 0.000
R63.1 Polydipsia
0.698 0.302 0.000
N41 Inflammatory diseases of prostate
0.697 0.303 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.695 0.305 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.695 0.305 0.000
K90-K93 Other diseases of the digestive system
0.695 0.305 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.694 0.306 0.000
R50 Fever of unknown origin
0.692 0.308 0.000
J44 Other chronic obstructive pulmonary disease
0.691 0.309 0.000
M05-M14 Inflammatory polyarthropathies
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.691 0.309 0.000
T66-T78 Other and unspecified effects of external causes
0.691 0.309 0.000
T33-T35 Frostbite
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.691 0.309 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.691 0.309 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.691 0.309 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.691 0.309 0.000
T00-T07 Injuries involving multiple body regions
0.691 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.691 0.309 0.000
S10-S19 Injuries to the neck
0.691 0.309 0.000
K63.1 Perforation of intestine (nontraumatic)
0.689 0.311 0.000
D61 Other aplastic anaemias
0.689 0.311 0.000
M50-M54 Other dorsopathies
0.689 0.311 0.000
S20-S29 Injuries to the thorax
0.688 0.312 0.000
I80 Phlebitis and thrombophlebitis
0.688 0.312 0.000
R56 Convulsions, not elsewhere classified
0.685 0.315 0.000
K55 Vascular disorders of intestine
0.683 0.317 0.000
F99-F99 Unspecified mental disorder
0.683 0.317 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
F70-F79 Mental retardation
0.683 0.317 0.000
F60-F69 Disorders of adult personality and behaviour
0.683 0.317 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.683 0.317 0.000
J94 Other pleural conditions
0.682 0.318 0.000
J91 Pleural effusion in conditions classified elsewhere
0.682 0.318 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.682 0.318 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.682 0.318 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
J02 Acute pharyngitis
0.681 0.319 0.000
R59.0 Localised enlarged lymph nodes
0.681 0.319 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.680 0.320 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.320 0.000
K63.9 Disease of intestine, unspecified
0.679 0.321 0.000
D73 Diseases of spleen
0.678 0.322 0.000
M80-M85 Disorders of bone density and structure
0.676 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.675 0.325 0.000
J03 Acute tonsillitis
0.675 0.325 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.675 0.325 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.673 0.326 0.000
M91-M94 Chondropathies
0.673 0.326 0.000
M60-M63 Disorders of muscles
0.673 0.326 0.000
M00-M03 Infectious arthropathies
0.673 0.326 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.673 0.327 0.000
R59.1 Generalised enlarged lymph nodes
0.673 0.327 0.000
Y43.3 Other antineoplastic drugs
0.669 0.331 0.000
B35-B49 Mycoses
0.669 0.331 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.669 0.331 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X60-X84 Intentional self-harm
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
W50-W64 Exposure to animate mechanical forces
0.669 0.331 0.000
W20-W49 Exposure to inanimate mechanical forces
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.668 0.332 0.000
F31.9 Bipolar affective disorder, unspecified
0.667 0.333 0.000
D50-D53 Nutritional anaemias
0.664 0.336 0.000
R59.9 Enlarged lymph nodes, unspecified
0.664 0.336 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.664 0.336 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.664 0.336 0.000
L10-L14 Bullous disorders
0.663 0.336 0.000
S50-S59 Injuries to the elbow and forearm
0.662 0.338 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.662 0.338 0.000
L05 Pilonidal cyst
0.662 0.338 0.000
I46 Cardiac arrest
0.660 0.340 0.000
B99-B99 Other infectious diseases
0.659 0.341 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.659 0.341 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.659 0.341 0.000
B65-B83 Helminthiases
0.659 0.341 0.000
B50-B64 Protozoal diseases
0.659 0.341 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
B15-B19 Viral hepatitis
0.659 0.341 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.659 0.341 0.000
A80-A89 Viral infections of the central nervous system
0.659 0.341 0.000
A75-A79 Rickettsioses
0.659 0.341 0.000
A70-A74 Other diseases caused by chlamydiae
0.659 0.341 0.000
A65-A69 Other spirochaetal diseases
0.659 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
A20-A28 Certain zoonotic bacterial diseases
0.659 0.341 0.000
A15-A19 Tuberculosis
0.659 0.341 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.659 0.341 0.000
I50 Heart failure
0.658 0.342 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.658 0.342 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.657 0.343 0.000
R77 Other abnormalities of plasma proteins
0.657 0.343 0.000
R76 Other abnormal immunological findings in serum
0.657 0.343 0.000
R74 Abnormal serum enzyme levels
0.657 0.343 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.657 0.343 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.657 0.343 0.000
R71 Abnormality of red blood cells
0.657 0.343 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.657 0.343 0.000
D75 Other diseases of blood and blood-forming organs
0.657 0.343 0.000
D74 Methaemoglobinaemia
0.657 0.343 0.000
D72 Other disorders of white blood cells
0.657 0.343 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.657 0.343 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.657 0.343 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.656 0.344 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.656 0.344 0.000
K59.8 Other specified functional intestinal disorders
0.656 0.344 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
M70-M79 Other soft tissue disorders
0.654 0.346 0.000
N30-N39 Other diseases of urinary system
0.654 0.346 0.000
M20 Acquired deformities of fingers and toes
0.654 0.346 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.654 0.346 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.654 0.346 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.653 0.347 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.652 0.348 0.000
I05-I09 Chronic rheumatic heart diseases
0.651 0.348 0.000
Y40 Systemic antibiotics
0.651 0.349 0.000
S70-S79 Injuries to the hip and thigh
0.649 0.351 0.000
J41 Simple and mucopurulent chronic bronchitis
0.645 0.355 0.000
J46 Status asthmaticus
0.645 0.355 0.000
J42 Unspecified chronic bronchitis
0.645 0.355 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.641 0.359 0.000
M34 Systemic sclerosis
0.641 0.359 0.000
M33 Dermatopolymyositis
0.641 0.359 0.000
M32 Systemic lupus erythematosus
0.641 0.359 0.000
M31 Other necrotising vasculopathies
0.641 0.359 0.000
M30 Polyarteritis nodosa and related conditions
0.641 0.359 0.000
M24 Other specific joint derangements
0.641 0.359 0.000
M22 Disorders of patella
0.641 0.359 0.000
M21 Other acquired deformities of limbs
0.641 0.359 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.641 0.359 0.000
H60-H62 Diseases of external ear
0.640 0.359 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.640 0.360 0.000
L60-L75 Disorders of skin appendages
0.639 0.361 0.000
N42 Other disorders of prostate
0.639 0.361 0.000
J95-J99 Other diseases of the respiratory system
0.638 0.361 0.000
N45 Orchitis and epididymitis
0.638 0.362 0.000
I51.7 Cardiomegaly
0.637 0.363 0.000
M25.5 Pain in joint
0.637 0.363 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.637 0.363 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.636 0.364 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.636 0.364 0.000
T81 Complications of procedures, not elsewhere classified
0.635 0.365 0.000
N25-N29 Other disorders of kidney and ureter
0.633 0.367 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.632 0.368 0.000
N48.6 Balanitis xerotica obliterans
0.632 0.368 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.631 0.369 0.000
M25.7 Osteophyte
0.629 0.371 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.627 0.372 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.627 0.373 0.000
R21 Rash and other nonspecific skin eruption
0.627 0.373 0.000
I00-I02 Acute rheumatic fever
0.627 0.373 0.000
C77.3 Axillary and upper limb lymph nodes
0.627 0.373 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.626 0.374 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.626 0.374 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.624 0.376 0.000
D68 Other coagulation defects
0.624 0.376 0.000
D67 Hereditary factor IX deficiency
0.624 0.376 0.000
D66 Hereditary factor VIII deficiency
0.624 0.376 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.624 0.376 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.623 0.377 0.000
N99-N99 Other disorders of the genitourinary system
0.622 0.377 0.000
N00-N08 Glomerular diseases
0.622 0.378 0.000
H65-H75 Diseases of middle ear and mastoid
0.622 0.378 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.621 0.379 0.000
J04 Acute laryngitis and tracheitis
0.621 0.379 0.000
J01 Acute sinusitis
0.621 0.379 0.000
J00 Acute nasopharyngitis [common cold]
0.621 0.379 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.620 0.379 0.000
D00-D09 In situ neoplasms
0.620 0.380 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.619 0.381 0.000
M23.8 Other internal derangements of knee
0.619 0.381 0.000
L03.3 Cellulitis of trunk
0.617 0.382 0.000
S62 Fracture at wrist and hand level
0.617 0.383 0.000
N50 Other disorders of male genital organs
0.615 0.385 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.615 0.385 0.000
N63 Unspecified lump in breast
0.614 0.386 0.000
W00-W19 Falls
0.613 0.387 0.000
L53 Other erythematous conditions
0.613 0.387 0.000
J17 Pneumonia in diseases classified elsewhere
0.611 0.388 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.611 0.388 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.611 0.388 0.000
J12 Viral pneumonia, not elsewhere classified
0.611 0.388 0.000
J11 Influenza, virus not identified
0.611 0.388 0.000
J10 Influenza due to identified influenza virus
0.611 0.388 0.000
J14 Pneumonia due to Haemophilus influenzae
0.611 0.388 0.000
J09 Influenza due to certain identified influenza virus
0.611 0.388 0.000
Y59 Other and unspecified vaccines and biological substances
0.611 0.388 0.000
Y58 Bacterial vaccines
0.611 0.388 0.000
Y57 Other and unspecified drugs and medicaments
0.611 0.388 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.611 0.388 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.611 0.388 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.611 0.388 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.611 0.388 0.000
Y52 Agents primarily affecting the cardiovascular system
0.611 0.388 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.611 0.388 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.611 0.388 0.000
Y48 Anaesthetics and therapeutic gases
0.611 0.388 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.611 0.388 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.611 0.388 0.000
Y44 Agents primarily affecting blood constituents
0.611 0.388 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.611 0.388 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.611 0.388 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.611 0.389 0.000
S61 Open wound of wrist and hand
0.611 0.389 0.000
M20.5 Other deformities of toe(s) (acquired)
0.609 0.391 0.000
L04 Acute lymphadenitis
0.609 0.391 0.000
L01 Impetigo
0.609 0.391 0.000
L00 Staphylococcal scalded skin syndrome
0.609 0.391 0.000
C15-C26 Malignant neoplasms of digestive organs
0.608 0.392 0.000
D61.9 Aplastic anaemia, unspecified
0.608 0.392 0.000
R07 Pain in throat and chest
0.607 0.393 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.607 0.393 0.000
N17-N19 Renal failure
0.606 0.394 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.606 0.394 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.605 0.394 0.000
T87 Complications peculiar to reattachment and amputation
0.605 0.394 0.000
T86 Failure and rejection of transplanted organs and tissues
0.605 0.394 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.605 0.394 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.605 0.395 0.000
K35-K38 Diseases of appendix
0.605 0.395 0.000
K70-K77 Diseases of liver
0.604 0.395 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.603 0.397 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.603 0.397 0.000
N46 Male infertility
0.603 0.397 0.000
N44 Torsion of testis
0.603 0.397 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.601 0.399 0.000
J33 Nasal polyp
0.601 0.399 0.000
M23.9 Internal derangement of knee, unspecified
0.600 0.400 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.600 0.400 0.000
M23.5 Chronic instability of knee
0.600 0.400 0.000
M23.4 Loose body in knee
0.600 0.400 0.000
M23.1 Discoid meniscus (congenital)
0.600 0.400 0.000
M23.0 Cystic meniscus
0.600 0.400 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.600 0.400 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.600 0.400 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.599 0.400 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.599 0.400 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.599 0.400 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.599 0.400 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.599 0.400 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.599 0.400 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.599 0.400 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.599 0.400 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.599 0.400 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.599 0.400 0.000
T36 Poisoning by systemic antibiotics
0.599 0.400 0.000
I60-I69 Cerebrovascular diseases
0.599 0.401 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.599 0.401 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.598 0.401 0.000
F38 Other mood [affective] disorders
0.598 0.402 0.000
F34 Persistent mood [affective] disorders
0.598 0.402 0.000
F33 Recurrent depressive disorder
0.598 0.402 0.000
F30 Manic episode
0.598 0.402 0.000
F39 Unspecified mood [affective] disorder
0.598 0.402 0.000
F20 Schizophrenia
0.597 0.403 0.000
J92.0 Pleural plaque with presence of asbestos
0.596 0.404 0.000
N60 Benign mammary dysplasia
0.596 0.404 0.000
M25.4 Effusion of joint
0.594 0.406 0.000
R01 Cardiac murmurs and other cardiac sounds
0.594 0.406 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.592 0.408 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.592 0.408 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.592 0.408 0.000
F02 Dementia in other diseases classified elsewhere
0.592 0.408 0.000
F01 Vascular dementia
0.592 0.408 0.000
F00 Dementia in Alzheimer's disease
0.592 0.408 0.000
F09 Unspecified organic or symptomatic mental disorder
0.592 0.408 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.592 0.408 0.000
O80-O84 Delivery
0.591 0.409 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.591 0.409 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.589 0.410 0.000
J06.9 Acute upper respiratory infection, unspecified
0.589 0.411 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.589 0.411 0.000
R94.7 Abnormal results of other endocrine function studies
0.589 0.411 0.000
R94.6 Abnormal results of thyroid function studies
0.589 0.411 0.000
R94.4 Abnormal results of kidney function studies
0.589 0.411 0.000
R94.3 Abnormal results of cardiovascular function studies
0.589 0.411 0.000
R94.2 Abnormal results of pulmonary function studies
0.589 0.411 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.589 0.411 0.000
R94.0 Abnormal results of function studies of central nervous system
0.589 0.411 0.000
O85-O92 Complications predominantly related to the puerperium
0.588 0.412 0.000
I38 Endocarditis, valve unspecified
0.588 0.412 0.000
T92 Sequelae of injuries of upper limb
0.588 0.412 0.000
R02 Gangrene, not elsewhere classified
0.585 0.414 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.585 0.415 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.585 0.415 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.585 0.415 0.000
Y98 Lifestyle-related condition
0.585 0.415 0.000
Y97 Environmental-pollution-related condition
0.585 0.415 0.000
Y96 Work-related condition
0.585 0.415 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.584 0.416 0.000
I49 Other cardiac arrhythmias
0.584 0.416 0.000
R60.0 Localised oedema
0.583 0.416 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.583 0.417 0.000
K63.4 Enteroptosis
0.582 0.418 0.000
K63.2 Fistula of intestine
0.582 0.418 0.000
K63.0 Abscess of intestine
0.582 0.418 0.000
I84 Haemorrhoids
0.580 0.420 0.000
I31 Other diseases of pericardium
0.580 0.420 0.000
L27 Dermatitis due to substances taken internally
0.580 0.420 0.000
H80-H83 Diseases of inner ear
0.579 0.421 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.578 0.422 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.577 0.423 0.000
H93 Other disorders of ear, not elsewhere classified
0.577 0.423 0.000
M47 Spondylosis
0.577 0.423 0.000
R49 Voice disturbances
0.576 0.423 0.000
J18.9 Pneumonia, unspecified
0.576 0.424 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.575 0.424 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.575 0.424 0.000
D62 Acute posthaemorrhagic anaemia
0.575 0.424 0.000
K55.9 Vascular disorder of intestine, unspecified
0.575 0.425 0.000
S05 Injury of eye and orbit
0.574 0.425 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.574 0.426 0.000
N48.8 Other specified disorders of penis
0.574 0.426 0.000
B34 Viral infection of unspecified site
0.574 0.426 0.000
K59.9 Functional intestinal disorder, unspecified
0.573 0.426 0.000
K59.4 Anal spasm
0.573 0.426 0.000
K59.3 Megacolon, not elsewhere classified
0.573 0.426 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.573 0.426 0.000
K59.1 Functional diarrhoea
0.573 0.426 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.571 0.429 0.000
F32 Depressive episode
0.570 0.430 0.000
O00-O08 Pregnancy with abortive outcome
0.570 0.430 0.000
Chapter VI Diseases of the nervous system
0.570 0.430 0.000
I52 Other heart disorders in diseases classified elsewhere
0.569 0.431 0.000
I48 Atrial fibrillation and flutter
0.569 0.431 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.569 0.431 0.000
I41 Myocarditis in diseases classified elsewhere
0.569 0.431 0.000
I40 Acute myocarditis
0.569 0.431 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.569 0.431 0.000
I37 Pulmonary valve disorders
0.569 0.431 0.000
I36 Nonrheumatic tricuspid valve disorders
0.569 0.431 0.000
I33 Acute and subacute endocarditis
0.569 0.431 0.000
I32 Pericarditis in diseases classified elsewhere
0.569 0.431 0.000
I30 Acute pericarditis
0.569 0.431 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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