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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181741409
log Bayes Factor = 4.98731
Chromosome 6   position 45,157,786  (GRCh37) Explore rs181741409 on Ensembl!
Variant rs181741409 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
I30-I52 Other forms of heart disease
0.968 0.032 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.960 0.040 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.950 0.050 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.949 0.051 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.949 0.051 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.940 0.060 0.000
Chapter VII Diseases of the eye and adnexa
0.928 0.072 0.000
F17.1 Harmful use
0.925 0.075 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.912 0.088 0.000
I51 Complications and ill-defined descriptions of heart disease
0.910 0.090 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.893 0.107 0.000
H30-H36 Disorders of choroid and retina
0.887 0.113 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.866 0.134 0.000
E10-E14 Diabetes mellitus
0.866 0.134 0.000
I71 Aortic aneurysm and dissection
0.859 0.141 0.000
I60-I69 Cerebrovascular diseases
0.858 0.142 0.000
Chapter VIII Diseases of the ear and mastoid process
0.857 0.143 0.000
C60-C63 Malignant neoplasms of male genital organs
0.850 0.150 0.000
E70-E90 Metabolic disorders
0.847 0.153 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.846 0.153 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.846 0.154 0.000
C51-C58 Malignant neoplasms of female genital organs
0.844 0.156 0.000
I46 Cardiac arrest
0.843 0.157 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.840 0.160 0.000
I05-I09 Chronic rheumatic heart diseases
0.840 0.160 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.839 0.161 0.000
C64-C68 Malignant neoplasms of urinary tract
0.832 0.168 0.000
Chapter I Certain infectious and parasitic diseases
0.829 0.171 0.000
I51.7 Cardiomegaly
0.828 0.172 0.000
I20-I25 Ischaemic heart diseases
0.828 0.172 0.000
Chapter X Diseases of the respiratory system
0.824 0.176 0.000
C15-C26 Malignant neoplasms of digestive organs
0.821 0.179 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.810 0.190 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.803 0.197 0.000
C79 Secondary malignant neoplasm of other sites
0.801 0.199 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.800 0.200 0.000
S90-S99 Injuries to the ankle and foot
0.796 0.204 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.794 0.206 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.794 0.206 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
F99-F99 Unspecified mental disorder
0.790 0.210 0.000
E10 Insulin-dependent diabetes mellitus
0.787 0.213 0.000
F30-F39 Mood [affective] disorders
0.787 0.213 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.785 0.215 0.000
I35 Nonrheumatic aortic valve disorders
0.783 0.217 0.000
S60-S69 Injuries to the wrist and hand
0.782 0.218 0.000
I51.8 Other ill-defined heart diseases
0.779 0.221 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.778 0.222 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.777 0.223 0.000
C34 Malignant neoplasm of bronchus and lung
0.775 0.225 0.000
I50 Heart failure
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.768 0.232 0.000
I73 Other peripheral vascular diseases
0.767 0.233 0.000
I74 Arterial embolism and thrombosis
0.766 0.234 0.000
C50-C50 Malignant neoplasm of breast
0.764 0.236 0.000
B95-B98 Bacterial, viral and other infectious agents
0.762 0.238 0.000
D00-D09 In situ neoplasms
0.761 0.239 0.000
H35 Other retinal disorders
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.754 0.246 0.000
I21 Acute myocardial infarction
0.754 0.246 0.000
L40-L45 Papulosquamous disorders
0.751 0.249 0.000
H33 Retinal detachments and breaks
0.750 0.250 0.000
C67 Malignant neoplasm of bladder
0.750 0.250 0.000
I49 Other cardiac arrhythmias
0.748 0.252 0.000
I38 Endocarditis, valve unspecified
0.746 0.253 0.000
W20-W49 Exposure to inanimate mechanical forces
0.746 0.254 0.000
C61 Malignant neoplasm of prostate
0.744 0.256 0.000
C56 Malignant neoplasm of ovary
0.741 0.259 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.741 0.259 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.736 0.264 0.000
H36 Retinal disorders in diseases classified elsewhere
0.736 0.264 0.000
C32 Malignant neoplasm of larynx
0.734 0.265 0.000
I46.9 Cardiac arrest, unspecified
0.733 0.267 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.731 0.269 0.000
L60-L75 Disorders of skin appendages
0.730 0.270 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.730 0.270 0.000
J30-J39 Other diseases of upper respiratory tract
0.727 0.273 0.000
L50-L54 Urticaria and erythema
0.727 0.273 0.000
I08 Multiple valve diseases
0.726 0.274 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.725 0.275 0.000
S80-S89 Injuries to the knee and lower leg
0.725 0.275 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.723 0.277 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
O36 Maternal care for other known or suspected foetal problems
0.722 0.278 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.719 0.281 0.000
E50-E64 Other nutritional deficiencies
0.718 0.282 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
S50-S59 Injuries to the elbow and forearm
0.716 0.284 0.000
I44 Atrioventricular and left bundle-branch block
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.715 0.285 0.000
E10.9 Without complications
0.711 0.289 0.000
H34 Retinal vascular occlusions
0.710 0.289 0.000
I24 Other acute ischaemic heart diseases
0.709 0.291 0.000
H52 Disorders of refraction and accommodation
0.708 0.292 0.000
I77 Other disorders of arteries and arterioles
0.707 0.293 0.000
E13 Other specified diabetes mellitus
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.293 0.000
F80-F89 Disorders of psychological development
0.706 0.293 0.000
F70-F79 Mental retardation
0.706 0.293 0.000
F60-F69 Disorders of adult personality and behaviour
0.706 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.293 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.706 0.293 0.000
H90-H95 Other disorders of ear
0.706 0.294 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.703 0.297 0.000
I78 Diseases of capillaries
0.700 0.300 0.000
Y95 Nosocomial condition
0.699 0.301 0.000
O00-O08 Pregnancy with abortive outcome
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.303 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.697 0.303 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.697 0.303 0.000
T00-T07 Injuries involving multiple body regions
0.697 0.303 0.000
S10-S19 Injuries to the neck
0.697 0.303 0.000
O23 Infections of genito-urinary tract in pregnancy
0.696 0.304 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
O60-O75 Complications of labour and delivery
0.695 0.305 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.695 0.305 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.694 0.306 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.694 0.306 0.000
I52 Other heart disorders in diseases classified elsewhere
0.694 0.306 0.000
I48 Atrial fibrillation and flutter
0.694 0.306 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.694 0.306 0.000
I41 Myocarditis in diseases classified elsewhere
0.694 0.306 0.000
I40 Acute myocarditis
0.694 0.306 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.694 0.306 0.000
I37 Pulmonary valve disorders
0.694 0.306 0.000
I36 Nonrheumatic tricuspid valve disorders
0.694 0.306 0.000
I33 Acute and subacute endocarditis
0.694 0.306 0.000
I32 Pericarditis in diseases classified elsewhere
0.694 0.306 0.000
I30 Acute pericarditis
0.694 0.306 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.692 0.307 0.000
C67.9 Bladder, unspecified
0.692 0.308 0.000
O41 Other disorders of amniotic fluid and membranes
0.692 0.308 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.692 0.308 0.000
O48 Prolonged pregnancy
0.691 0.309 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.691 0.309 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.690 0.310 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.311 0.000
I21.9 Acute myocardial infarction, unspecified
0.689 0.311 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.688 0.311 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.688 0.311 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.688 0.311 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.688 0.311 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.688 0.311 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.688 0.311 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.688 0.311 0.000
F11 Mental and behavioural disorders due to use of opioids
0.688 0.311 0.000
L20-L30 Dermatitis and eczema
0.688 0.312 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.688 0.312 0.000
I62 Other nontraumatic intracranial haemorrhage
0.687 0.313 0.000
C80 Malignant neoplasm without specification of site
0.686 0.314 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.314 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.686 0.314 0.000
E86 Volume depletion
0.685 0.315 0.000
I73.9 Peripheral vascular disease, unspecified
0.684 0.316 0.000
E00-E07 Disorders of thyroid gland
0.683 0.317 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.319 0.000
I72 Other aneurysm
0.681 0.319 0.000
I70 Atherosclerosis
0.681 0.319 0.000
E40-E46 Malnutrition
0.681 0.319 0.000
E20-E35 Disorders of other endocrine glands
0.681 0.319 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.319 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.319 0.000
Y10-Y34 Event of undetermined intent
0.680 0.319 0.000
Y00-Y09 Assault
0.680 0.319 0.000
X85-X99 Assault
0.680 0.319 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.319 0.000
X50-X57 Overexertion, travel and privation
0.680 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.680 0.319 0.000
X30-X39 Exposure to forces of nature
0.680 0.319 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.319 0.000
X10-X19 Contact with heat and hot substances
0.680 0.319 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.319 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.319 0.000
W75-W84 Other accidental threats to breathing
0.680 0.319 0.000
W65-W74 Accidental drowning and submersion
0.680 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.319 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.319 0.000
V95-V97 Air and space transport accidents
0.680 0.319 0.000
V90-V94 Water transport accidents
0.680 0.319 0.000
V80-V89 Other land transport accidents
0.680 0.319 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.319 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.319 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.319 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.319 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.319 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.319 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.319 0.000
O20 Haemorrhage in early pregnancy
0.680 0.320 0.000
O85-O92 Complications predominantly related to the puerperium
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.679 0.321 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.679 0.321 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.678 0.322 0.000
C77.5 Intrapelvic lymph nodes
0.678 0.322 0.000
C77.3 Axillary and upper limb lymph nodes
0.674 0.326 0.000
F17.9 Unspecified mental and behavioural disorder
0.674 0.326 0.000
F17.8 Other mental and behavioural disorders
0.674 0.326 0.000
F17.7 Residual and late-onset psychotic disorder
0.674 0.326 0.000
F17.6 Amnesic syndrome
0.674 0.326 0.000
F17.5 Psychotic disorder
0.674 0.326 0.000
F17.4 Withdrawal state with delirium
0.674 0.326 0.000
F17.3 Withdrawal state
0.674 0.326 0.000
F17.0 Acute intoxication
0.674 0.326 0.000
W00-W19 Falls
0.673 0.327 0.000
E14 Unspecified diabetes mellitus
0.673 0.327 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.671 0.328 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.669 0.331 0.000
T93 Sequelae of injuries of lower limb
0.667 0.333 0.000
F17.2 Dependence syndrome
0.667 0.333 0.000
C77.1 Intrathoracic lymph nodes
0.666 0.334 0.000
H55-H59 Other disorders of eye and adnexa
0.666 0.334 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.666 0.334 0.000
H10-H13 Disorders of conjunctiva
0.666 0.334 0.000
I10-I15 Hypertensive diseases
0.665 0.335 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
H60-H62 Diseases of external ear
0.664 0.336 0.000
I67 Other cerebrovascular diseases
0.662 0.338 0.000
C79.2 Secondary malignant neoplasm of skin
0.661 0.339 0.000
O80-O84 Delivery
0.660 0.340 0.000
C78.2 Secondary malignant neoplasm of pleura
0.659 0.341 0.000
C15 Malignant neoplasm of oesophagus
0.657 0.343 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.657 0.343 0.000
H65-H75 Diseases of middle ear and mastoid
0.656 0.344 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.656 0.344 0.000
C78.7 Secondary malignant neoplasm of liver
0.655 0.345 0.000
I42 Cardiomyopathy
0.655 0.345 0.000
H35.8 Other specified retinal disorders
0.654 0.346 0.000
L10-L14 Bullous disorders
0.654 0.346 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.654 0.346 0.000
C34.9 Bronchus or lung, unspecified
0.653 0.347 0.000
I51.9 Heart disease, unspecified
0.652 0.348 0.000
I51.6 Cardiovascular disease, unspecified
0.652 0.348 0.000
I51.5 Myocardial degeneration
0.652 0.348 0.000
I51.4 Myocarditis, unspecified
0.652 0.348 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.652 0.348 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.652 0.348 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.652 0.348 0.000
I51.0 Cardiac septal defect, acquired
0.652 0.348 0.000
E83 Disorders of mineral metabolism
0.652 0.348 0.000
J40-J47 Chronic lower respiratory diseases
0.652 0.348 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
F99 Mental disorder, not otherwise specified
0.650 0.350 0.000
E88 Other metabolic disorders
0.650 0.350 0.000
I46.0 Cardiac arrest with successful resuscitation
0.649 0.350 0.000
S42 Fracture of shoulder and upper arm
0.648 0.352 0.000
C77.9 Lymph node, unspecified
0.647 0.353 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.646 0.354 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.646 0.354 0.000
H33.2 Serous retinal detachment
0.646 0.354 0.000
S91 Open wound of ankle and foot
0.645 0.354 0.000
I60 Subarachnoid haemorrhage
0.645 0.355 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.640 0.359 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.640 0.359 0.000
C31 Malignant neoplasm of accessory sinuses
0.640 0.359 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.640 0.359 0.000
C37 Malignant neoplasm of thymus
0.640 0.359 0.000
C33 Malignant neoplasm of trachea
0.640 0.359 0.000
L40 Psoriasis
0.640 0.360 0.000
I45 Other conduction disorders
0.640 0.360 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.639 0.361 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.639 0.361 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.638 0.362 0.000
H53-H54 Visual disturbances and blindness
0.637 0.362 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.636 0.364 0.000
H31 Other disorders of choroid
0.636 0.364 0.000
H30 Chorioretinal inflammation
0.636 0.364 0.000
I26 Pulmonary embolism
0.634 0.366 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.634 0.366 0.000
C18 Malignant neoplasm of colon
0.633 0.367 0.000
Y86 Sequelae of other accidents
0.632 0.368 0.000
S00-S09 Injuries to the head
0.629 0.371 0.000
O42 Premature rupture of membranes
0.629 0.371 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.629 0.371 0.000
I31 Other diseases of pericardium
0.628 0.372 0.000
F43 Reaction to severe stress, and adjustment disorders
0.627 0.372 0.000
H36.0 Diabetic retinopathy
0.628 0.372 0.000
H52.0 Hypermetropia
0.626 0.374 0.000
C34.1 Upper lobe, bronchus or lung
0.625 0.375 0.000
C77.0 Lymph nodes of head, face and neck
0.625 0.375 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.625 0.375 0.000
C16 Malignant neoplasm of stomach
0.624 0.375 0.000
I61 Intracerebral haemorrhage
0.624 0.376 0.000
E10.3 With ophthalmic complications
0.623 0.377 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.621 0.379 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.621 0.379 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.621 0.379 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.621 0.379 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.621 0.379 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.621 0.379 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.621 0.379 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.621 0.379 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.621 0.379 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.621 0.379 0.000
T36 Poisoning by systemic antibiotics
0.621 0.379 0.000
S62 Fracture at wrist and hand level
0.621 0.379 0.000
E12 Malnutrition-related diabetes mellitus
0.621 0.379 0.000
C32.0 Glottis
0.621 0.379 0.000
H50 Other strabismus
0.620 0.380 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.619 0.381 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.618 0.382 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.618 0.382 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.617 0.383 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.616 0.384 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.616 0.384 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.616 0.384 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.616 0.384 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.616 0.384 0.000
I71.0 Dissection of aorta [any part]
0.616 0.384 0.000
J60-J70 Lung diseases due to external agents
0.615 0.385 0.000
I47 Paroxysmal tachycardia
0.615 0.385 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.615 0.385 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.615 0.385 0.000
B35-B49 Mycoses
0.614 0.385 0.000
F31 Bipolar affective disorder
0.614 0.386 0.000
Y85 Sequelae of transport accidents
0.614 0.386 0.000
I35.0 Aortic (valve) stenosis
0.613 0.387 0.000
O47 False labour
0.613 0.387 0.000
D45 Polycythaemia vera
0.612 0.387 0.000
O04 Medical abortion
0.612 0.388 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.611 0.389 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.609 0.390 0.000
C62 Malignant neoplasm of testis
0.609 0.390 0.000
C60 Malignant neoplasm of penis
0.609 0.390 0.000
I49.8 Other specified cardiac arrhythmias
0.609 0.391 0.000
S92 Fracture of foot, except ankle
0.608 0.392 0.000
E85 Amyloidosis
0.608 0.392 0.000
E84 Cystic fibrosis
0.608 0.392 0.000
E79 Disorders of purine and pyrimidine metabolism
0.608 0.392 0.000
E77 Disorders of glycoprotein metabolism
0.608 0.392 0.000
E76 Disorders of glycosaminoglycan metabolism
0.608 0.392 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.608 0.392 0.000
E74 Other disorders of carbohydrate metabolism
0.608 0.392 0.000
E73 Lactose intolerance
0.608 0.392 0.000
E72 Other disorders of amino-acid metabolism
0.608 0.392 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.608 0.392 0.000
E70 Disorders of aromatic amino-acid metabolism
0.608 0.392 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.608 0.392 0.000
J90-J94 Other diseases of pleura
0.607 0.393 0.000
O29 Complications of anaesthesia during pregnancy
0.607 0.393 0.000
O28 Abnormal findings on antenatal screening of mother
0.607 0.393 0.000
O24 Diabetes mellitus in pregnancy
0.607 0.393 0.000
O22 Venous complications in pregnancy
0.607 0.393 0.000
O21 Excessive vomiting in pregnancy
0.607 0.393 0.000
O25 Malnutrition in pregnancy
0.607 0.393 0.000
O45 Premature separation of placenta [abruptio placentae]
0.607 0.393 0.000
O44 Placenta praevia
0.607 0.393 0.000
O43 Placental disorders
0.607 0.393 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.607 0.393 0.000
O33 Maternal care for known or suspected disproportion
0.607 0.393 0.000
O31 Complications specific to multiple gestation
0.607 0.393 0.000
O30 Multiple gestation
0.607 0.393 0.000
O40 Polyhydramnios
0.607 0.393 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.606 0.393 0.000
I27 Other pulmonary heart diseases
0.606 0.394 0.000
H80-H83 Diseases of inner ear
0.606 0.394 0.000
I50.0 Congestive heart failure
0.605 0.394 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.605 0.395 0.000
C53 Malignant neoplasm of cervix uteri
0.605 0.395 0.000
C51 Malignant neoplasm of vulva
0.605 0.395 0.000
C58 Malignant neoplasm of placenta
0.605 0.395 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.605 0.395 0.000
C52 Malignant neoplasm of vagina
0.605 0.395 0.000
I46.1 Sudden cardiac death, so described
0.604 0.396 0.000
S68 Traumatic amputation of wrist and hand
0.604 0.396 0.000
F32 Depressive episode
0.604 0.396 0.000
Y44 Agents primarily affecting blood constituents
0.603 0.397 0.000
C77.8 Lymph nodes of multiple regions
0.602 0.397 0.000
C77.4 Inguinal and lower limb lymph nodes
0.602 0.397 0.000
I09 Other rheumatic heart diseases
0.602 0.398 0.000
I07 Rheumatic tricuspid valve diseases
0.602 0.398 0.000
I06 Rheumatic aortic valve diseases
0.602 0.398 0.000
I05 Rheumatic mitral valve diseases
0.602 0.398 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.601 0.398 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.601 0.398 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.601 0.398 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.601 0.398 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.601 0.399 0.000
I08.0 Disorders of both mitral and aortic valves
0.601 0.399 0.000
W22 Striking against or struck by other objects
0.601 0.399 0.000
F45 Somatoform disorders
0.599 0.401 0.000
O36.8 Maternal care for other specified foetal problems
0.598 0.402 0.000
Y40 Systemic antibiotics
0.598 0.402 0.000
J34 Other disorders of nose and nasal sinuses
0.598 0.402 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.598 0.402 0.000
S72 Fracture of femur
0.597 0.403 0.000
F10.0 Acute intoxication
0.597 0.403 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.597 0.403 0.000
I34 Nonrheumatic mitral valve disorders
0.597 0.403 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.597 0.403 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.596 0.404 0.000
C66 Malignant neoplasm of ureter
0.596 0.404 0.000
C65 Malignant neoplasm of renal pelvis
0.596 0.404 0.000
C50 Malignant neoplasm of breast
0.596 0.404 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.596 0.404 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.595 0.405 0.000
C25 Malignant neoplasm of pancreas
0.595 0.405 0.000
B99-B99 Other infectious diseases
0.594 0.406 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.594 0.406 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.594 0.406 0.000
B65-B83 Helminthiases
0.594 0.406 0.000
B50-B64 Protozoal diseases
0.594 0.406 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.594 0.406 0.000
B15-B19 Viral hepatitis
0.594 0.406 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.594 0.406 0.000
A80-A89 Viral infections of the central nervous system
0.594 0.406 0.000
A75-A79 Rickettsioses
0.594 0.406 0.000
A70-A74 Other diseases caused by chlamydiae
0.594 0.406 0.000
A65-A69 Other spirochaetal diseases
0.594 0.406 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.594 0.406 0.000
A20-A28 Certain zoonotic bacterial diseases
0.594 0.406 0.000
A15-A19 Tuberculosis
0.594 0.406 0.000
I23 Certain current complications following acute myocardial infarction
0.593 0.407 0.000
L50 Urticaria
0.593 0.407 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.593 0.407 0.000
E13.9 Without complications
0.592 0.407 0.000
I35.1 Aortic (valve) insufficiency
0.592 0.408 0.000
D09 Carcinoma in situ of other and unspecified sites
0.592 0.408 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.590 0.409 0.000
I49.4 Other and unspecified premature depolarisation
0.590 0.410 0.000
I63 Cerebral infarction
0.589 0.411 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.589 0.411 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.589 0.411 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.589 0.411 0.000
C21 Malignant neoplasm of anus and anal canal
0.589 0.411 0.000
C17 Malignant neoplasm of small intestine
0.589 0.411 0.000
C23 Malignant neoplasm of gallbladder
0.589 0.411 0.000
C54 Malignant neoplasm of corpus uteri
0.588 0.412 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.587 0.412 0.000
A00-A09 Intestinal infectious diseases
0.587 0.413 0.000
T40.2 Other opioids
0.587 0.413 0.000
E80.4 Gilbert's syndrome
0.585 0.415 0.000
H34.8 Other retinal vascular occlusions
0.584 0.416 0.000
I50.9 Heart failure, unspecified
0.584 0.416 0.000
E16 Other disorders of pancreatic internal secretion
0.584 0.416 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.584 0.416 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.582 0.417 0.000
O41.0 Oligohydramnios
0.581 0.419 0.000
H51 Other disorders of binocular movement
0.581 0.419 0.000
H49 Paralytic strabismus
0.581 0.419 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.581 0.419 0.000
I22 Subsequent myocardial infarction
0.579 0.420 0.000
F10.2 Dependence syndrome
0.577 0.423 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.576 0.424 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.576 0.424 0.000
Y98 Lifestyle-related condition
0.576 0.424 0.000
Y97 Environmental-pollution-related condition
0.576 0.424 0.000
Y96 Work-related condition
0.576 0.424 0.000
O36.5 Maternal care for poor foetal growth
0.576 0.424 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.574 0.425 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.574 0.425 0.000
C79.6 Secondary malignant neoplasm of ovary
0.574 0.425 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.574 0.425 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.574 0.425 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.574 0.425 0.000
I28 Other diseases of pulmonary vessels
0.574 0.426 0.000
L82 Seborrhoeic keratosis
0.574 0.426 0.000
J33 Nasal polyp
0.573 0.427 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.573 0.427 0.000
C20 Malignant neoplasm of rectum
0.572 0.428 0.000
D06 Carcinoma in situ of cervix uteri
0.571 0.429 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.571 0.429 0.000
J95-J99 Other diseases of the respiratory system
0.571 0.429 0.000
S99 Other and unspecified injuries of ankle and foot
0.571 0.429 0.000
S98 Traumatic amputation of ankle and foot
0.571 0.429 0.000
S97 Crushing injury of ankle and foot
0.571 0.429 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.571 0.429 0.000
S95 Injury of blood vessels at ankle and foot level
0.571 0.429 0.000
S94 Injury of nerves at ankle and foot level
0.571 0.429 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.571 0.429 0.000
S90 Superficial injury of ankle and foot
0.571 0.429 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.571 0.429 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.570 0.430 0.000
T98 Sequelae of other and unspecified effects of external causes
0.570 0.430 0.000
T95 Sequelae of burns, corrosions and frostbite
0.570 0.430 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.570 0.430 0.000
T92 Sequelae of injuries of upper limb
0.570 0.430 0.000
T91 Sequelae of injuries of neck and trunk
0.570 0.430 0.000
T90 Sequelae of injuries of head
0.570 0.430 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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