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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs183369189
log Bayes Factor = 1.70547
Chromosome 2   position 155,812,392  (GRCh37) Explore rs183369189 on Ensembl!
Variant rs183369189 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.973 0.027 0.000
D12.0 Caecum
0.966 0.034 0.000
D12.5 Sigmoid colon
0.963 0.037 0.000
D12.4 Descending colon
0.931 0.069 0.000
D12.2 Ascending colon
0.904 0.096 0.000
D12.3 Transverse colon
0.876 0.124 0.000
D12.9 Anus and anal canal
0.772 0.228 0.000
D12.7 Rectosigmoid junction
0.769 0.231 0.000
D12.8 Rectum
0.743 0.257 0.000
D12.1 Appendix
0.698 0.302 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.671 0.329 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.647 0.353 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.645 0.355 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
D50.9 Iron deficiency anaemia, unspecified
0.631 0.369 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.627 0.373 0.000
D50 Iron deficiency anaemia
0.625 0.375 0.000
# Top node
0.621 0.379 0.000
D50-D53 Nutritional anaemias
0.618 0.382 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.617 0.383 0.000
T66-T78 Other and unspecified effects of external causes
0.615 0.385 0.000
T42.4 Benzodiazepines
0.602 0.398 0.000
Chapter II Neoplasms
0.594 0.406 0.000
S20-S29 Injuries to the thorax
0.594 0.406 0.000
M20-M25 Other joint disorders
0.590 0.410 0.000
D10-D36 Benign neoplasms
0.590 0.410 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.588 0.412 0.000
M23 Internal derangement of knee
0.586 0.414 0.000
M80-M85 Disorders of bone density and structure
0.583 0.417 0.000
M70-M79 Other soft tissue disorders
0.583 0.417 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.583 0.417 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.577 0.423 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.576 0.424 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.575 0.425 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.572 0.428 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.572 0.428 0.000
T78 Adverse effects, not elsewhere classified
0.570 0.430 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.567 0.433 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.557 0.443 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.554 0.446 0.000
M84 Disorders of continuity of bone
0.545 0.455 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.545 0.455 0.000
D50.8 Other iron deficiency anaemias
0.545 0.455 0.000
T78.4 Allergy, unspecified
0.541 0.459 0.000
Chapter I Certain infectious and parasitic diseases
0.539 0.461 0.000
C64-C68 Malignant neoplasms of urinary tract
0.536 0.464 0.000
M50-M54 Other dorsopathies
0.535 0.465 0.000
T68 Hypothermia
0.529 0.471 0.000
T45.0 Antiallergic and antiemetic drugs
0.528 0.472 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.525 0.475 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.524 0.476 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.523 0.477 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.523 0.477 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.521 0.479 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.520 0.480 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.520 0.480 0.000
M50 Cervical disk disorders
0.520 0.480 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.519 0.481 0.000
M77 Other enthesopathies
0.517 0.483 0.000
Chapter VIII Diseases of the ear and mastoid process
0.517 0.483 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.517 0.483 0.000
S29 Other and unspecified injuries of thorax
0.516 0.484 0.000
M91-M94 Chondropathies
0.514 0.486 0.000
M79.6 Pain in limb
0.514 0.486 0.000
S90-S99 Injuries to the ankle and foot
0.512 0.488 0.000
M45-M49 Spondylopathies
0.511 0.489 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.509 0.491 0.000
S50-S59 Injuries to the elbow and forearm
0.508 0.492 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.505 0.495 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.501 0.499 0.000
Chapter VI Diseases of the nervous system
0.501 0.499 0.000
H65-H75 Diseases of middle ear and mastoid
0.500 0.500 0.000
M79.66 Pain in limb (Lower leg)
0.500 0.500 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.499 0.501 0.000
M24 Other specific joint derangements
0.499 0.501 0.000
T79-T79 Certain early complications of trauma
0.499 0.501 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.497 0.503 0.000
D12.6 Colon, unspecified
0.496 0.504 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.496 0.504 0.000
S40-S49 Injuries to the shoulder and upper arm
0.493 0.507 0.000
T43.2 Other and unspecified antidepressants
0.493 0.507 0.000
M50.2 Other cervical disk displacement
0.493 0.507 0.000
M23.0 Cystic meniscus
0.492 0.508 0.000
D55-D59 Haemolytic anaemias
0.490 0.510 0.000
M50.0 Cervical disk disorder with myelopathy
0.489 0.511 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.489 0.511 0.000
M86-M90 Other osteopathies
0.488 0.512 0.000
D22 Melanocytic naevi
0.488 0.512 0.000
M60-M63 Disorders of muscles
0.487 0.513 0.000
D30 Benign neoplasm of urinary organs
0.485 0.515 0.000
T39.1 4-Aminophenol derivatives
0.484 0.516 0.000
Q60-Q64 Congenital malformations of the urinary system
0.483 0.517 0.000
M85 Other disorders of bone density and structure
0.483 0.517 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.483 0.517 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.481 0.519 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.481 0.519 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.481 0.519 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.481 0.519 0.000
T36 Poisoning by systemic antibiotics
0.481 0.519 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.481 0.519 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.480 0.520 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.479 0.521 0.000
A30-A49 Other bacterial diseases
0.477 0.523 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.477 0.523 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.476 0.524 0.000
M05-M14 Inflammatory polyarthropathies
0.475 0.525 0.000
O42 Premature rupture of membranes
0.475 0.525 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.474 0.526 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.474 0.526 0.000
D00-D09 In situ neoplasms
0.472 0.528 0.000
S22.4 Multiple fractures of ribs
0.471 0.529 0.000
D52 Folate deficiency anaemia
0.469 0.531 0.000
S10-S19 Injuries to the neck
0.469 0.531 0.000
M76 Enthesopathies of lower limb, excluding foot
0.469 0.531 0.000
S70-S79 Injuries to the hip and thigh
0.465 0.535 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.465 0.535 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.464 0.536 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.464 0.536 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.464 0.536 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.464 0.536 0.000
T42.3 Barbiturates
0.464 0.536 0.000
T42.2 Succinimides and oxazolidinediones
0.464 0.536 0.000
T42.1 Iminostilbenes
0.464 0.536 0.000
T42.0 Hydantoin derivatives
0.464 0.536 0.000
T33-T35 Frostbite
0.463 0.537 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.463 0.537 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.463 0.537 0.000
T00-T07 Injuries involving multiple body regions
0.463 0.537 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.462 0.538 0.000
T43.9 Psychotropic drug, unspecified
0.461 0.539 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.461 0.539 0.000
T43.6 Psychostimulants with abuse potential
0.461 0.539 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.461 0.539 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.461 0.539 0.000
M82 Osteoporosis in diseases classified elsewhere
0.461 0.539 0.000
S29.9 Unspecified injury of thorax
0.460 0.540 0.000
M21 Other acquired deformities of limbs
0.460 0.540 0.000
A00-A09 Intestinal infectious diseases
0.458 0.542 0.000
M34 Systemic sclerosis
0.456 0.544 0.000
M23.4 Loose body in knee
0.456 0.544 0.000
Q80-Q89 Other congenital malformations
0.456 0.544 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.455 0.545 0.000
H73 Other disorders of tympanic membrane
0.454 0.546 0.000
O24 Diabetes mellitus in pregnancy
0.452 0.548 0.000
M23.1 Discoid meniscus (congenital)
0.451 0.549 0.000
D17 Benign lipomatous neoplasm
0.451 0.549 0.000
Q00-Q07 Congenital malformations of the nervous system
0.449 0.551 0.000
D80-D89 Certain disorders involving the immune mechanism
0.449 0.551 0.000
D50.1 Sideropenic dysphagia
0.448 0.551 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.448 0.552 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.445 0.555 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.445 0.555 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.444 0.556 0.000
D53 Other nutritional anaemias
0.443 0.557 0.000
D26 Other benign neoplasms of uterus
0.443 0.557 0.000
T75 Effects of other external causes
0.441 0.559 0.000
T74 Maltreatment syndromes
0.441 0.559 0.000
T73 Effects of other deprivation
0.441 0.559 0.000
T70 Effects of air pressure and water pressure
0.441 0.559 0.000
T69 Other effects of reduced temperature
0.441 0.559 0.000
T67 Effects of heat and light
0.441 0.559 0.000
T71 Asphyxiation
0.441 0.559 0.000
T66 Unspecified effects of radiation
0.441 0.559 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.441 0.559 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.441 0.559 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.440 0.560 0.000
O23 Infections of genito-urinary tract in pregnancy
0.440 0.560 0.000
T78.2 Anaphylactic shock, unspecified
0.440 0.560 0.000
C51-C58 Malignant neoplasms of female genital organs
0.439 0.561 0.000
M23.8 Other internal derangements of knee
0.438 0.562 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.438 0.562 0.000
D05 Carcinoma in situ of breast
0.438 0.562 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.438 0.562 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.437 0.563 0.000
M71 Other bursopathies
0.436 0.564 0.000
D16 Benign neoplasm of bone and articular cartilage
0.436 0.564 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.436 0.564 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.435 0.565 0.000
M77.1 Lateral epicondylitis
0.435 0.565 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.434 0.566 0.000
S22.40 Multiple fractures of ribs (closed)
0.433 0.567 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.432 0.568 0.000
M93 Other osteochondropathies
0.432 0.568 0.000
M00-M03 Infectious arthropathies
0.432 0.568 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.432 0.568 0.000
M23.9 Internal derangement of knee, unspecified
0.431 0.569 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.430 0.570 0.000
A08 Viral and other specified intestinal infections
0.430 0.570 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.429 0.571 0.000
M46 Other inflammatory spondylopathies
0.427 0.573 0.000
D45 Polycythaemia vera
0.427 0.573 0.000
Chapter XXII Codes for special purposes
0.426 0.573 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.426 0.574 0.000
M79.5 Residual foreign body in soft tissue
0.426 0.574 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.426 0.574 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.426 0.574 0.000
S26 Injury of heart
0.426 0.574 0.000
S25 Injury of blood vessels of thorax
0.426 0.574 0.000
S24 Injury of nerves and spinal cord at thorax level
0.426 0.574 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.426 0.574 0.000
S21 Open wound of thorax
0.426 0.574 0.000
S51 Open wound of forearm
0.425 0.575 0.000
T14 Injury of unspecified body region
0.425 0.575 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.424 0.576 0.000
D32 Benign neoplasm of meninges
0.424 0.576 0.000
S99 Other and unspecified injuries of ankle and foot
0.424 0.576 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.423 0.577 0.000
M33 Dermatopolymyositis
0.423 0.577 0.000
M32 Systemic lupus erythematosus
0.423 0.577 0.000
M30 Polyarteritis nodosa and related conditions
0.423 0.577 0.000
S42 Fracture of shoulder and upper arm
0.423 0.577 0.000
D31 Benign neoplasm of eye and adnexa
0.423 0.577 0.000
D29 Benign neoplasm of male genital organs
0.423 0.577 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.423 0.577 0.000
D19 Benign neoplasm of mesothelial tissue
0.423 0.577 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.423 0.577 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.422 0.578 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.421 0.579 0.000
T45.8 Other primarily systemic and haematological agents
0.421 0.579 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.421 0.579 0.000
T45.6 Fibrinolysis-affecting drugs
0.421 0.579 0.000
T45.5 Anticoagulants
0.421 0.579 0.000
T45.4 Iron and its compounds
0.421 0.579 0.000
T45.3 Enzymes, not elsewhere classified
0.421 0.579 0.000
T45.2 Vitamins, not elsewhere classified
0.421 0.579 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.421 0.579 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.421 0.579 0.000
H73.8 Other specified disorders of tympanic membrane
0.420 0.580 0.000
D05.1 Intraductal carcinoma in situ
0.420 0.580 0.000
M83 Adult osteomalacia
0.418 0.582 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.418 0.582 0.000
S27 Injury of other and unspecified intrathoracic organs
0.417 0.583 0.000
M87 Osteonecrosis
0.416 0.584 0.000
A15-A19 Tuberculosis
0.416 0.584 0.000
S32 Fracture of lumbar spine and pelvis
0.416 0.584 0.000
H66 Suppurative and unspecified otitis media
0.416 0.584 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.416 0.584 0.000
G57 Mononeuropathies of lower limb
0.415 0.585 0.000
S20 Superficial injury of thorax
0.415 0.585 0.000
M79.1 Myalgia
0.415 0.585 0.000
M45 Ankylosing spondylitis
0.414 0.586 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.414 0.586 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.413 0.587 0.000
M24.1 Other articular cartilage disorders
0.413 0.587 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.413 0.587 0.000
Q35-Q37 Cleft lip and cleft palate
0.413 0.587 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.413 0.587 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.412 0.588 0.000
M48 Other spondylopathies
0.412 0.588 0.000
S22.3 Fracture of rib
0.410 0.590 0.000
M77.9 Enthesopathy, unspecified
0.410 0.590 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.410 0.590 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.410 0.590 0.000
T39.4 Antirheumatics, not elsewhere classified
0.410 0.590 0.000
T39.2 Pyrazolone derivatives
0.410 0.590 0.000
Q17 Other congenital malformations of ear
0.410 0.590 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.409 0.590 0.000
T78.9 Adverse effect, unspecified
0.409 0.591 0.000
T78.8 Other adverse effects, not elsewhere classified
0.409 0.591 0.000
M79.2 Neuralgia and neuritis, unspecified
0.408 0.591 0.000
H72 Perforation of tympanic membrane
0.408 0.592 0.000
M11 Other crystal arthropathies
0.407 0.593 0.000
O43 Placental disorders
0.406 0.594 0.000
C91 Lymphoid leukaemia
0.406 0.594 0.000
O85-O92 Complications predominantly related to the puerperium
0.406 0.594 0.000
B65-B83 Helminthiases
0.405 0.595 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.405 0.595 0.000
M79.63 Pain in limb (Forearm)
0.405 0.595 0.000
S31 Open wound of abdomen, lower back and pelvis
0.405 0.595 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.404 0.596 0.000
A41 Other septicaemia
0.403 0.597 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.403 0.597 0.000
C73 Malignant neoplasm of thyroid gland
0.403 0.597 0.000
Q50-Q56 Congenital malformations of genital organs
0.403 0.597 0.000
M77.5 Other enthesopathy of foot
0.402 0.598 0.000
C54 Malignant neoplasm of corpus uteri
0.402 0.598 0.000
M05 Seropositive rheumatoid arthritis
0.402 0.598 0.000
Q63 Other congenital malformations of kidney
0.402 0.598 0.000
O40 Polyhydramnios
0.401 0.599 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.401 0.599 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.401 0.599 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.401 0.599 0.000
A08.4 Viral intestinal infection, unspecified
0.400 0.600 0.000
S22.5 Flail chest
0.400 0.600 0.000
T50.8 Diagnostic agents
0.400 0.600 0.000
T50.7 Analeptics and opioid receptor antagonists
0.400 0.600 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.400 0.600 0.000
T50.5 Appetite depressants
0.400 0.600 0.000
T50.4 Drugs affecting uric acid metabolism
0.400 0.600 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.400 0.600 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.400 0.600 0.000
T50.1 Loop [high-ceiling] diuretics
0.400 0.600 0.000
T50.0 Mineralocorticoids and their antagonists
0.400 0.600 0.000
T40.2 Other opioids
0.399 0.601 0.000
M31 Other necrotising vasculopathies
0.399 0.601 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.398 0.601 0.000
M79.7 Fibromyalgia
0.398 0.602 0.000
D59 Acquired haemolytic anaemia
0.398 0.602 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.398 0.602 0.000
D30.0 Kidney
0.396 0.604 0.000
H65 Nonsuppurative otitis media
0.396 0.604 0.000
M85.6 Other cyst of bone
0.396 0.604 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.396 0.604 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.394 0.606 0.000
B99-B99 Other infectious diseases
0.394 0.606 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.394 0.606 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.393 0.607 0.000
D69 Purpura and other haemorrhagic conditions
0.393 0.607 0.000
C66 Malignant neoplasm of ureter
0.393 0.607 0.000
O42.9 Premature rupture of membranes, unspecified
0.393 0.607 0.000
S36 Injury of intra-abdominal organs
0.391 0.609 0.000
Q10.0 Congenital ptosis
0.391 0.609 0.000
M84.9 Disorder of continuity of bone, unspecified
0.391 0.609 0.000
M84.8 Other disorders of continuity of bone
0.391 0.609 0.000
M84.4 Pathological fracture, not elsewhere classified
0.391 0.609 0.000
M84.3 Stress fracture, not elsewhere classified
0.391 0.609 0.000
M84.2 Delayed union of fracture
0.391 0.609 0.000
M79.9 Soft tissue disorder, unspecified
0.391 0.609 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.391 0.609 0.000
M79.3 Panniculitis, unspecified
0.391 0.609 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.390 0.609 0.000
M25 Other joint disorders, not elsewhere classified
0.390 0.610 0.000
M79.8 Other specified soft tissue disorders
0.389 0.611 0.000
O41 Other disorders of amniotic fluid and membranes
0.389 0.611 0.000
M53 Other dorsopathies, not elsewhere classified
0.389 0.611 0.000
O32.8 Maternal care for other malpresentation of foetus
0.389 0.611 0.000
M15-M19 Arthrosis
0.389 0.611 0.000
A80-A89 Viral infections of the central nervous system
0.388 0.612 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.388 0.612 0.000
S22.1 Multiple fractures of thoracic spine
0.388 0.612 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.387 0.613 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.387 0.613 0.000
M62 Other disorders of muscle
0.387 0.613 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.387 0.613 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.387 0.613 0.000
D68 Other coagulation defects
0.387 0.613 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.387 0.613 0.000
B50-B64 Protozoal diseases
0.387 0.613 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.387 0.613 0.000
A75-A79 Rickettsioses
0.387 0.613 0.000
A70-A74 Other diseases caused by chlamydiae
0.387 0.613 0.000
A65-A69 Other spirochaetal diseases
0.387 0.613 0.000
A20-A28 Certain zoonotic bacterial diseases
0.387 0.613 0.000
G57.8 Other mononeuropathies of lower limb
0.386 0.614 0.000
G81 Hemiplegia
0.386 0.614 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.385 0.615 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.385 0.615 0.000
M23.5 Chronic instability of knee
0.385 0.615 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.385 0.615 0.000
C65 Malignant neoplasm of renal pelvis
0.385 0.615 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.385 0.615 0.000
O32.0 Maternal care for unstable lie
0.384 0.616 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.384 0.616 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.384 0.616 0.000
B95-B98 Bacterial, viral and other infectious agents
0.384 0.616 0.000
M70.6 Trochanteric bursitis
0.383 0.617 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.383 0.617 0.000
T78.3 Angioneurotic oedema
0.382 0.617 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.382 0.618 0.000
S42.0 Fracture of clavicle
0.382 0.618 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.382 0.618 0.000
M65-M68 Disorders of synovium and tendon
0.381 0.619 0.000
M84.0 Malunion of fracture
0.380 0.620 0.000
D22.0 Melanocytic naevi of lip
0.380 0.620 0.000
A49 Bacterial infection of unspecified site
0.379 0.621 0.000
M85.8 Other specified disorders of bone density and structure
0.379 0.621 0.000
Q85 Phakomatoses, not elsewhere classified
0.379 0.621 0.000
O30 Multiple gestation
0.379 0.621 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.379 0.621 0.000
M24.0 Loose body in joint
0.379 0.621 0.000
M40-M43 Deforming dorsopathies
0.378 0.621 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.377 0.623 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.377 0.623 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.377 0.623 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.377 0.623 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.377 0.623 0.000
C54.1 Endometrium
0.376 0.624 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.376 0.624 0.000
S22.9 Fracture of bony thorax, part unspecified
0.375 0.625 0.000
S22.8 Fracture of other parts of bony thorax
0.375 0.625 0.000
O45 Premature separation of placenta [abruptio placentae]
0.375 0.625 0.000
O33 Maternal care for known or suspected disproportion
0.375 0.625 0.000
O31 Complications specific to multiple gestation
0.375 0.625 0.000
O44 Placenta praevia
0.375 0.625 0.000
Q61 Cystic kidney disease
0.375 0.625 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.374 0.626 0.000
G70-G73 Diseases of myoneural junction and muscle
0.374 0.626 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.374 0.626 0.000
M82.1 Osteoporosis in endocrine disorders
0.374 0.626 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.374 0.626 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.374 0.626 0.000
T46.7 Peripheral vasodilators
0.374 0.626 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.374 0.626 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.374 0.626 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.374 0.626 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.374 0.626 0.000
T46.1 Calcium-channel blockers
0.374 0.626 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.374 0.626 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.374 0.626 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.373 0.626 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.373 0.627 0.000
M93.9 Osteochondropathy, unspecified
0.373 0.627 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.373 0.627 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.373 0.627 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.373 0.627 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.373 0.627 0.000
O29 Complications of anaesthesia during pregnancy
0.373 0.627 0.000
O28 Abnormal findings on antenatal screening of mother
0.373 0.627 0.000
O22 Venous complications in pregnancy
0.373 0.627 0.000
O25 Malnutrition in pregnancy
0.373 0.627 0.000
M50.9 Cervical disk disorder, unspecified
0.373 0.627 0.000
M50.8 Other cervical disk disorders
0.373 0.627 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.372 0.628 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.372 0.628 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.372 0.628 0.000
S37 Injury of urinary and pelvic organs
0.372 0.628 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.372 0.628 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.372 0.628 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.372 0.628 0.000
M77.4 Metatarsalgia
0.372 0.628 0.000
M94 Other disorders of cartilage
0.371 0.629 0.000
O32.1 Maternal care for breech presentation
0.371 0.629 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.371 0.629 0.000
M77.3 Calcaneal spur
0.371 0.629 0.000
M77.2 Periarthritis of wrist
0.371 0.629 0.000
M77.0 Medial epicondylitis
0.371 0.629 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.371 0.629 0.000
T13 Other injuries of lower limb, level unspecified
0.371 0.629 0.000
T11 Other injuries of upper limb, level unspecified
0.371 0.629 0.000
T09 Other injuries of spine and trunk, level unspecified
0.371 0.629 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.371 0.629 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.371 0.629 0.000
T12 Fracture of lower limb, level unspecified
0.371 0.629 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.371 0.629 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.371 0.629 0.000
T10 Fracture of upper limb, level unspecified
0.371 0.629 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.371 0.629 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.371 0.629 0.000
T08 Fracture of spine, level unspecified
0.371 0.629 0.000
C60-C63 Malignant neoplasms of male genital organs
0.371 0.629 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.370 0.630 0.000
S29.8 Other specified injuries of thorax
0.370 0.630 0.000
S29.7 Multiple injuries of thorax
0.370 0.630 0.000
S29.0 Injury of muscle and tendon at thorax level
0.370 0.630 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.370 0.630 0.000
O21 Excessive vomiting in pregnancy
0.370 0.630 0.000
M92 Other juvenile osteochondrosis
0.369 0.631 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.369 0.631 0.000
D30.3 Bladder
0.369 0.631 0.000
D43.2 Brain, unspecified
0.369 0.631 0.000
M79.68 Pain in limb (Other)
0.369 0.631 0.000
M79.61 Pain in limb (Shoulder region)
0.369 0.631 0.000
D47.4 Osteomyelofibrosis
0.369 0.631 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.368 0.632 0.000
S10 Superficial injury of neck
0.367 0.632 0.000
S98 Traumatic amputation of ankle and foot
0.367 0.633 0.000
S97 Crushing injury of ankle and foot
0.367 0.633 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.367 0.633 0.000
S95 Injury of blood vessels at ankle and foot level
0.367 0.633 0.000
S94 Injury of nerves at ankle and foot level
0.367 0.633 0.000
M24.5 Contracture of joint
0.367 0.633 0.000
M79.67 Pain in limb (Ankle and foot)
0.367 0.633 0.000
M49 Spondylopathies in diseases classified elsewhere
0.366 0.633 0.000
C67 Malignant neoplasm of bladder
0.366 0.633 0.000
H74 Other disorders of middle ear and mastoid
0.366 0.634 0.000
M80 Osteoporosis with pathological fracture
0.366 0.634 0.000
G83 Other paralytic syndromes
0.366 0.634 0.000
M24.2 Disorder of ligament
0.366 0.634 0.000
G30-G32 Other degenerative diseases of the nervous system
0.366 0.634 0.000
D36 Benign neoplasm of other and unspecified sites
0.366 0.634 0.000
G57.6 Lesion of plantar nerve
0.366 0.634 0.000
H69 Other disorders of Eustachian tube
0.365 0.635 0.000
Q18 Other congenital malformations of face and neck
0.365 0.635 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.365 0.635 0.000
Q15 Other congenital malformations of eye
0.365 0.635 0.000
Q14 Congenital malformations of posterior segment of eye
0.365 0.635 0.000
Q13 Congenital malformations of anterior segment of eye
0.365 0.635 0.000
Q12 Congenital lens malformations
0.365 0.635 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.365 0.635 0.000
M87.9 Osteonecrosis, unspecified
0.365 0.635 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.365 0.635 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.364 0.636 0.000
S59 Other and unspecified injuries of forearm
0.364 0.636 0.000
S58 Traumatic amputation of forearm
0.364 0.636 0.000
S57 Crushing injury of forearm
0.364 0.636 0.000
S56 Injury of muscle and tendon at forearm level
0.364 0.636 0.000
S55 Injury of blood vessels at forearm level
0.364 0.636 0.000
S54 Injury of nerves at forearm level
0.364 0.636 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.364 0.636 0.000
A48 Other bacterial diseases, not elsewhere classified
0.364 0.636 0.000
O32.4 Maternal care for high head at term
0.364 0.636 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.364 0.636 0.000
T63 Toxic effect of contact with venomous animals
0.364 0.636 0.000
S50 Superficial injury of forearm
0.364 0.636 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.364 0.636 0.000
M23.3 Other meniscus derangements
0.364 0.636 0.000
M23.49 Loose body in knee-Unspec lig/men
0.363 0.637 0.000
D52.9 Folate deficiency anaemia, unspecified
0.363 0.637 0.000
O47 False labour
0.363 0.637 0.000
O20 Haemorrhage in early pregnancy
0.362 0.638 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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