TreeWAS – Variant ID: rs185053659

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S00-S09 Injuries to the head	0.096	0.904	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.096	0.904	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.094	0.906	0.000
S02 Fracture of skull and facial bones	0.093	0.907	0.000
S20-S29 Injuries to the thorax	0.090	0.910	0.000
S80-S89 Injuries to the knee and lower leg	0.087	0.912	0.000
T81 Complications of procedures, not elsewhere classified	0.086	0.914	0.000
S02.6 Fracture of mandible	0.083	0.917	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.083	0.917	0.000
S01 Open wound of head	0.082	0.917	0.000
S80 Superficial injury of lower leg	0.082	0.918	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.082	0.918	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.079	0.921	0.000
S80.9 Superficial injury of lower leg, unspecified	0.078	0.922	0.000
S02.0 Fracture of vault of skull	0.078	0.922	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.078	0.922	0.000
S22.4 Multiple fractures of ribs	0.077	0.923	0.000
S02.60 Fracture of mandible (closed)	0.076	0.923	0.000
S00 Superficial injury of head	0.075	0.925	0.000
S02.5 Fracture of tooth	0.074	0.925	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.074	0.926	0.000
S22.40 Multiple fractures of ribs (closed)	0.073	0.927	0.000
S02.4 Fracture of malar and maxillary bones	0.073	0.927	0.000
S29 Other and unspecified injuries of thorax	0.072	0.927	0.000
T66-T78 Other and unspecified effects of external causes	0.072	0.928	0.000
S70-S79 Injuries to the hip and thigh	0.072	0.928	0.000
S09 Other and unspecified injuries of head	0.072	0.928	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.072	0.928	0.000
S01.8 Open wound of other parts of head	0.071	0.929	0.000
S02.1 Fracture of base of skull	0.070	0.930	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.070	0.930	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.070	0.930	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.069	0.931	0.000
S40-S49 Injuries to the shoulder and upper arm	0.069	0.931	0.000
S50-S59 Injuries to the elbow and forearm	0.069	0.931	0.000
S08 Traumatic amputation of part of head	0.069	0.931	0.000
S07 Crushing injury of head	0.069	0.931	0.000
S05 Injury of eye and orbit	0.069	0.931	0.000
S04 Injury of cranial nerves	0.069	0.931	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.069	0.931	0.000
T79-T79 Certain early complications of trauma	0.069	0.931	0.000
T33-T35 Frostbite	0.069	0.931	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.069	0.931	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.069	0.931	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.069	0.931	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.069	0.931	0.000
T00-T07 Injuries involving multiple body regions	0.069	0.931	0.000
S10-S19 Injuries to the neck	0.069	0.931	0.000
S01.1 Open wound of eyelid and periocular area	0.069	0.931	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.069	0.931	0.000
S81 Open wound of lower leg	0.069	0.931	0.000
S06 Intracranial injury	0.067	0.932	0.000
T87 Complications peculiar to reattachment and amputation	0.067	0.933	0.000
T86 Failure and rejection of transplanted organs and tissues	0.067	0.933	0.000
S01.0 Open wound of scalp	0.067	0.933	0.000
S02.00 Fracture of vault of skull (closed)	0.067	0.933	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.067	0.933	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.067	0.933	0.000
S02.8 Fractures of other skull and facial bones	0.067	0.933	0.000
S02.7 Multiple fractures involving skull and facial bones	0.067	0.933	0.000
S02.3 Fracture of orbital floor	0.067	0.933	0.000
S20 Superficial injury of thorax	0.067	0.933	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.066	0.934	0.000
S60-S69 Injuries to the wrist and hand	0.066	0.934	0.000
S27 Injury of other and unspecified intrathoracic organs	0.066	0.934	0.000
S90-S99 Injuries to the ankle and foot	0.066	0.934	0.000
S89 Other and unspecified injuries of lower leg	0.066	0.934	0.000
S02.2 Fracture of nasal bones	0.065	0.935	0.000
S00.0 Superficial injury of scalp	0.065	0.935	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.064	0.935	0.000
S26 Injury of heart	0.064	0.935	0.000
S25 Injury of blood vessels of thorax	0.064	0.935	0.000
S24 Injury of nerves and spinal cord at thorax level	0.064	0.935	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.064	0.935	0.000
S21 Open wound of thorax	0.064	0.935	0.000
T88.5 Other complications of anaesthesia	0.064	0.936	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.064	0.936	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.063	0.937	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.063	0.937	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.063	0.937	0.000
S88 Traumatic amputation of lower leg	0.063	0.937	0.000
S87 Crushing injury of lower leg	0.063	0.937	0.000
S86 Injury of muscle and tendon at lower leg level	0.063	0.937	0.000
S85 Injury of blood vessels at lower leg level	0.063	0.937	0.000
S84 Injury of nerves at lower leg level	0.063	0.937	0.000
S22.2 Fracture of sternum	0.063	0.937	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.062	0.937	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.062	0.938	0.000
T81.9 Unspecified complication of procedure	0.062	0.938	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.062	0.938	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.062	0.938	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.062	0.938	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.062	0.938	0.000
M70-M79 Other soft tissue disorders	0.060	0.938	0.002
S02.50 Fracture of tooth (closed)	0.061	0.939	0.000
S29.9 Unspecified injury of thorax	0.060	0.940	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.060	0.940	0.000
S02.61 Fracture of mandible (open)	0.060	0.940	0.000
T85.2 Mechanical complication of intraocular lens	0.060	0.940	0.000
S80.8 Other superficial injuries of lower leg	0.060	0.940	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.060	0.940	0.000
M20-M25 Other joint disorders	0.060	0.940	0.000
S01.7 Multiple open wounds of head	0.059	0.941	0.000
S01.4 Open wound of cheek and temporomandibular area	0.059	0.941	0.000
S01.3 Open wound of ear	0.059	0.941	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.059	0.941	0.000
M79.6 Pain in limb	0.059	0.941	0.000
S80.7 Multiple superficial injuries of lower leg	0.059	0.941	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.059	0.941	0.000
S80.0 Contusion of knee	0.059	0.941	0.000
S22.9 Fracture of bony thorax, part unspecified	0.059	0.941	0.000
S22.8 Fracture of other parts of bony thorax	0.059	0.941	0.000
S22.5 Flail chest	0.059	0.941	0.000
S22.1 Multiple fractures of thoracic spine	0.059	0.941	0.000
S22.0 Fracture of thoracic vertebra	0.058	0.942	0.000
S01.9 Open wound of head, part unspecified	0.058	0.942	0.000
M05-M14 Inflammatory polyarthropathies	0.058	0.942	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.056	0.943	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.056	0.943	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.056	0.943	0.000
T83.2 Mechanical complication of graft of urinary organ	0.056	0.943	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.056	0.943	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.056	0.943	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.056	0.944	0.000
S02.01 Fracture of vault of skull (open)	0.056	0.944	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.056	0.944	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.056	0.944	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.056	0.944	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.056	0.944	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.056	0.944	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.056	0.944	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.056	0.944	0.000
S79 Other and unspecified injuries of hip and thigh	0.055	0.944	0.000
S00.1 Contusion of eyelid and periocular area	0.055	0.944	0.000
T78 Adverse effects, not elsewhere classified	0.055	0.945	0.000
S22.41 Multiple fractures of ribs (open)	0.055	0.945	0.000
M31 Other necrotising vasculopathies	0.055	0.945	0.000
S51 Open wound of forearm	0.055	0.945	0.000
S09.9 Unspecified injury of head	0.054	0.946	0.000
S22.3 Fracture of rib	0.054	0.946	0.000
M80-M85 Disorders of bone density and structure	0.054	0.946	0.000
S40 Superficial injury of shoulder and upper arm	0.054	0.946	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.054	0.946	0.000
S00.7 Multiple superficial injuries of head	0.054	0.946	0.000
S00.5 Superficial injury of lip and oral cavity	0.054	0.946	0.000
S00.4 Superficial injury of ear	0.054	0.946	0.000
S00.3 Superficial injury of nose	0.054	0.946	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.054	0.946	0.000
S02.10 Fracture of base of skull (closed)	0.054	0.946	0.000
M35 Other systemic involvement of connective tissue	0.054	0.946	0.000
S02.51 Fracture of tooth (open)	0.053	0.946	0.000
T88.9 Complication of surgical and medical care, unspecified	0.053	0.947	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.053	0.947	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.053	0.947	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.053	0.947	0.000
T88.2 Shock due to anaesthesia	0.053	0.947	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.053	0.947	0.000
T88.0 Infection following immunisation	0.053	0.947	0.000
S01.2 Open wound of nose	0.053	0.947	0.000
S81.8 Open wound of other parts of lower leg	0.053	0.947	0.000
M50-M54 Other dorsopathies	0.053	0.947	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.053	0.947	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.052	0.948	0.000
S29.8 Other specified injuries of thorax	0.052	0.948	0.000
S29.7 Multiple injuries of thorax	0.052	0.948	0.000
S29.0 Injury of muscle and tendon at thorax level	0.052	0.948	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.052	0.948	0.000
S81.9 Open wound of lower leg, part unspecified	0.052	0.948	0.000
T75 Effects of other external causes	0.052	0.948	0.000
T74 Maltreatment syndromes	0.052	0.948	0.000
T73 Effects of other deprivation	0.052	0.948	0.000
T70 Effects of air pressure and water pressure	0.052	0.948	0.000
T69 Other effects of reduced temperature	0.052	0.948	0.000
T67 Effects of heat and light	0.052	0.948	0.000
T71 Asphyxiation	0.052	0.948	0.000
T68 Hypothermia	0.052	0.948	0.000
T66 Unspecified effects of radiation	0.052	0.948	0.000
S78 Traumatic amputation of hip and thigh	0.052	0.948	0.000
S77 Crushing injury of hip and thigh	0.052	0.948	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.052	0.948	0.000
S75 Injury of blood vessels at hip and thigh level	0.052	0.948	0.000
S74 Injury of nerves at hip and thigh level	0.052	0.948	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.052	0.948	0.000
S71 Open wound of hip and thigh	0.052	0.948	0.000
S70 Superficial injury of hip and thigh	0.052	0.948	0.000
S09.8 Other specified injuries of head	0.052	0.948	0.000
S09.7 Multiple injuries of head	0.052	0.948	0.000
S09.2 Traumatic rupture of ear drum	0.052	0.948	0.000
S09.1 Injury of muscle and tendon of head	0.052	0.948	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.052	0.948	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.052	0.948	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.052	0.948	0.000
T80.6 Other serum reactions	0.052	0.948	0.000
T80.5 Anaphylactic shock due to serum	0.052	0.948	0.000
T80.4 Rh incompatibility reaction	0.052	0.948	0.000
T80.3 ABO incompatibility reaction	0.052	0.948	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.052	0.948	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.052	0.948	0.000
M06 Other rheumatoid arthritis	0.052	0.948	0.000
S72 Fracture of femur	0.052	0.948	0.000
T18 Foreign body in alimentary tract	0.051	0.948	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.051	0.948	0.000
S00.9 Superficial injury of head, part unspecified	0.051	0.949	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.051	0.949	0.000
S99 Other and unspecified injuries of ankle and foot	0.051	0.949	0.000
M86-M90 Other osteopathies	0.051	0.949	0.000
S83.2 Tear of meniscus, current	0.050	0.949	0.000
M79.66 Pain in limb (Lower leg)	0.051	0.949	0.000
S02.11 Fracture of base of skull (open)	0.050	0.949	0.000
T19 Foreign body in genito-urinary tract	0.050	0.949	0.000
T17 Foreign body in respiratory tract	0.050	0.949	0.000
T15 Foreign body on external eye	0.050	0.949	0.000
T16 Foreign body in ear	0.050	0.949	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.050	0.950	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.050	0.950	0.000
M23 Internal derangement of knee	0.050	0.950	0.000
M35.3 Polymyalgia rheumatica	0.050	0.950	0.000
S89.9 Unspecified injury of lower leg	0.050	0.950	0.000
M40-M43 Deforming dorsopathies	0.050	0.950	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.050	0.950	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.050	0.950	0.000
S48 Traumatic amputation of shoulder and upper arm	0.050	0.950	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.050	0.950	0.000
S44 Injury of nerves at shoulder and upper arm level	0.050	0.950	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.050	0.950	0.000
S41 Open wound of shoulder and upper arm	0.050	0.950	0.000
S47 Crushing injury of shoulder and upper arm	0.050	0.950	0.000
S59 Other and unspecified injuries of forearm	0.050	0.950	0.000
S58 Traumatic amputation of forearm	0.050	0.950	0.000
S57 Crushing injury of forearm	0.050	0.950	0.000
S56 Injury of muscle and tendon at forearm level	0.050	0.950	0.000
S55 Injury of blood vessels at forearm level	0.050	0.950	0.000
S54 Injury of nerves at forearm level	0.050	0.950	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.050	0.950	0.000
M65-M68 Disorders of synovium and tendon	0.050	0.950	0.000
M72 Fibroblastic disorders	0.049	0.950	0.001
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.050	0.950	0.000
S03.4 Sprain and strain of jaw	0.050	0.950	0.000
S03.3 Dislocation of other and unspecified parts of head	0.050	0.950	0.000
S03.2 Dislocation of tooth	0.050	0.950	0.000
S03.1 Dislocation of septal cartilage of nose	0.050	0.950	0.000
S03.0 Dislocation of jaw	0.050	0.950	0.000
S04.9 Injury of unspecified cranial nerve	0.050	0.950	0.000
S04.8 Injury of other cranial nerves	0.050	0.950	0.000
S04.7 Injury of accessory nerve	0.050	0.950	0.000
S04.6 Injury of acoustic nerve	0.050	0.950	0.000
S04.5 Injury of facial nerve	0.050	0.950	0.000
S04.4 Injury of abducent nerve	0.050	0.950	0.000
S04.3 Injury of trigeminal nerve	0.050	0.950	0.000
S04.2 Injury of trochlear nerve	0.050	0.950	0.000
S04.1 Injury of oculomotor nerve	0.050	0.950	0.000
S04.0 Injury of optic nerve and pathways	0.050	0.950	0.000
S05.9 Injury of eye and orbit, part unspecified	0.050	0.950	0.000
S05.8 Other injuries of eye and orbit	0.050	0.950	0.000
S05.7 Avulsion of eye	0.050	0.950	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.050	0.950	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.050	0.950	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.050	0.950	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.050	0.950	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.050	0.950	0.000
S05.1 Contusion of eyeball and orbital tissues	0.050	0.950	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.050	0.950	0.000
S07.9 Crushing injury of head, part unspecified	0.050	0.950	0.000
S07.8 Crushing injury of other parts of head	0.050	0.950	0.000
S07.1 Crushing injury of skull	0.050	0.950	0.000
S07.0 Crushing injury of face	0.050	0.950	0.000
S08.9 Traumatic amputation of unspecified part of head	0.050	0.950	0.000
S08.8 Traumatic amputation of other parts of head	0.050	0.950	0.000
S08.1 Traumatic amputation of ear	0.050	0.950	0.000
S08.0 Avulsion of scalp	0.050	0.950	0.000
S19 Other and unspecified injuries of neck	0.049	0.950	0.000
S17 Crushing injury of neck	0.049	0.950	0.000
S15 Injury of blood vessels at neck level	0.049	0.950	0.000
S14 Injury of nerves and spinal cord at neck level	0.049	0.950	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.049	0.950	0.000
S12 Fracture of neck	0.049	0.950	0.000
S11 Open wound of neck	0.049	0.950	0.000
S10 Superficial injury of neck	0.049	0.950	0.000
S18 Traumatic amputation at neck level	0.049	0.950	0.000
S16 Injury of muscle and tendon at neck level	0.049	0.950	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.049	0.950	0.000
T05 Traumatic amputations involving multiple body regions	0.049	0.950	0.000
T04 Crushing injuries involving multiple body regions	0.049	0.950	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.049	0.950	0.000
T02 Fractures involving multiple body regions	0.049	0.950	0.000
T01 Open wounds involving multiple body regions	0.049	0.950	0.000
T00 Superficial injuries involving multiple body regions	0.049	0.950	0.000
T07 Unspecified multiple injuries	0.049	0.950	0.000
T14 Injury of unspecified body region	0.049	0.950	0.000
T13 Other injuries of lower limb, level unspecified	0.049	0.950	0.000
T11 Other injuries of upper limb, level unspecified	0.049	0.950	0.000
T09 Other injuries of spine and trunk, level unspecified	0.049	0.950	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.049	0.950	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.049	0.950	0.000
T12 Fracture of lower limb, level unspecified	0.049	0.950	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.049	0.950	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.049	0.950	0.000
T10 Fracture of upper limb, level unspecified	0.049	0.950	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.049	0.950	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.049	0.950	0.000
T08 Fracture of spine, level unspecified	0.049	0.950	0.000
T25 Burn and corrosion of ankle and foot	0.049	0.950	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.049	0.950	0.000
T23 Burn and corrosion of wrist and hand	0.049	0.950	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.049	0.950	0.000
T21 Burn and corrosion of trunk	0.049	0.950	0.000
T20 Burn and corrosion of head and neck	0.049	0.950	0.000
T28 Burn and corrosion of other internal organs	0.049	0.950	0.000
T27 Burn and corrosion of respiratory tract	0.049	0.950	0.000
T26 Burn and corrosion confined to eye and adnexa	0.049	0.950	0.000
T32 Corrosions classified according to extent of body surface involved	0.049	0.950	0.000
T31 Burns classified according to extent of body surface involved	0.049	0.950	0.000
T30 Burn and corrosion, body region unspecified	0.049	0.950	0.000
T29 Burns and corrosions of multiple body regions	0.049	0.950	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.049	0.950	0.000
T34 Frostbite with tissue necrosis	0.049	0.950	0.000
T33 Superficial frostbite	0.049	0.950	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.049	0.950	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.049	0.950	0.000
S37 Injury of urinary and pelvic organs	0.049	0.950	0.000
S36 Injury of intra-abdominal organs	0.049	0.950	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.049	0.950	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.049	0.950	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.049	0.950	0.000
S31 Open wound of abdomen, lower back and pelvis	0.049	0.950	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.049	0.950	0.000
M54 Dorsalgia	0.050	0.950	0.000
S81.7 Multiple open wounds of lower leg	0.049	0.951	0.000
S81.0 Open wound of knee	0.049	0.951	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.049	0.951	0.000
S50 Superficial injury of forearm	0.049	0.951	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.049	0.951	0.000
M79.64 Pain in limb (Hand)	0.049	0.951	0.000
S22.20 Fracture of sternum (closed)	0.049	0.951	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.049	0.951	0.000
M91-M94 Chondropathies	0.049	0.951	0.000
S62 Fracture at wrist and hand level	0.049	0.951	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.049	0.951	0.000
S27.0 Traumatic pneumothorax	0.049	0.951	0.000
S06.9 Intracranial injury, unspecified	0.048	0.951	0.000
S06.8 Other intracranial injuries	0.048	0.951	0.000
S06.7 Intracranial injury with prolonged coma	0.048	0.951	0.000
S06.4 Epidural haemorrhage	0.048	0.951	0.000
S06.3 Focal brain injury	0.048	0.951	0.000
S06.2 Diffuse brain injury	0.048	0.951	0.000
S06.1 Traumatic cerebral oedema	0.048	0.951	0.000
S06.0 Concussion	0.048	0.951	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.048	0.951	0.000
S06.5 Traumatic subdural haemorrhage	0.048	0.951	0.000
S68 Traumatic amputation of wrist and hand	0.049	0.951	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.048	0.951	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.048	0.951	0.000
T86.4 Liver transplant failure and rejection	0.048	0.951	0.000
T86.3 Heart-lung transplant failure and rejection	0.048	0.951	0.000
T86.2 Heart transplant failure and rejection	0.048	0.951	0.000
T86.1 Kidney transplant failure and rejection	0.048	0.951	0.000
T86.0 Bone-marrow transplant rejection	0.048	0.951	0.000
T87.6 Other and unspecified complications of amputation stump	0.048	0.951	0.000
T87.5 Necrosis of amputation stump	0.048	0.951	0.000
T87.4 Infection of amputation stump	0.048	0.951	0.000
T87.3 Neuroma of amputation stump	0.048	0.951	0.000
T87.2 Complications of other reattached body part	0.048	0.951	0.000
T87.1 Complications of reattached (part of) lower extremity	0.048	0.951	0.000
T87.0 Complications of reattached (part of) upper extremity	0.048	0.951	0.000
M31.6 Other giant cell arteritis	0.048	0.951	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.048	0.951	0.000
S64 Injury of nerves at wrist and hand level	0.048	0.952	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.048	0.952	0.000
S67 Crushing injury of wrist and hand	0.048	0.952	0.000
S02.31 Fracture of orbital floor (open)	0.048	0.952	0.000
S02.30 Fracture of orbital floor (closed)	0.048	0.952	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.048	0.952	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.048	0.952	0.000
S02.81 Fractures of other skull and facial bones (open)	0.048	0.952	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.048	0.952	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.048	0.952	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.048	0.952	0.000
S20.7 Multiple superficial injuries of thorax	0.048	0.952	0.000
S20.4 Other superficial injuries of back wall of thorax	0.048	0.952	0.000
S20.3 Other superficial injuries of front wall of thorax	0.048	0.952	0.000
S20.2 Contusion of thorax	0.048	0.952	0.000
S20.1 Other and unspecified superficial injuries of breast	0.048	0.952	0.000
S20.0 Contusion of breast	0.048	0.952	0.000
M79.8 Other specified soft tissue disorders	0.048	0.952	0.000
M24 Other specific joint derangements	0.048	0.952	0.000
M76 Enthesopathies of lower limb, excluding foot	0.047	0.952	0.001
S83.7 Injury to multiple structures of knee	0.048	0.952	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.048	0.952	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.048	0.952	0.000
S83.3 Tear of articular cartilage of knee, current	0.048	0.952	0.000
S83.1 Dislocation of knee	0.048	0.952	0.000
S83.0 Dislocation of patella	0.048	0.952	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.048	0.952	0.000
S69 Other and unspecified injuries of wrist and hand	0.048	0.952	0.000
S65 Injury of blood vessels at wrist and hand level	0.048	0.952	0.000
S60 Superficial injury of wrist and hand	0.048	0.952	0.000
T88.4 Failed or difficult intubation	0.048	0.952	0.000
M23.3 Other meniscus derangements	0.048	0.952	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.048	0.952	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.047	0.952	0.000
S27.9 Injury of unspecified intrathoracic organ	0.047	0.953	0.000
S27.8 Injury of other specified intrathoracic organs	0.047	0.953	0.000
S27.7 Multiple injuries of intrathoracic organs	0.047	0.953	0.000
S27.6 Injury of pleura	0.047	0.953	0.000
S27.5 Injury of thoracic trachea	0.047	0.953	0.000
S27.4 Injury of bronchus	0.047	0.953	0.000
S27.3 Other injuries of lung	0.047	0.953	0.000
S27.2 Traumatic heamopneumothorax	0.047	0.953	0.000
S27.1 Traumatic haemothorax	0.047	0.953	0.000
S98 Traumatic amputation of ankle and foot	0.047	0.953	0.000
S97 Crushing injury of ankle and foot	0.047	0.953	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.047	0.953	0.000
S95 Injury of blood vessels at ankle and foot level	0.047	0.953	0.000
S94 Injury of nerves at ankle and foot level	0.047	0.953	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.047	0.953	0.000
S90 Superficial injury of ankle and foot	0.047	0.953	0.000
S89.8 Other specified injuries of lower leg	0.047	0.953	0.000
S89.7 Multiple injuries of lower leg	0.047	0.953	0.000
S89.1 Other specified injuries of lower leg	0.047	0.953	0.000
S89.0 Multiple injuries of lower leg	0.047	0.953	0.000
T92 Sequelae of injuries of upper limb	0.047	0.953	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.047	0.953	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.047	0.953	0.000
S02.21 Fracture of nasal bones (open)	0.047	0.953	0.000
M11 Other crystal arthropathies	0.047	0.953	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.047	0.953	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.046	0.953	0.000
S21.9 Open wound of thorax, part unspecified	0.046	0.953	0.000
S21.8 Open wound of other parts of thorax	0.046	0.953	0.000
S21.7 Multiple open wounds of thoracic wall	0.046	0.953	0.000
S21.2 Open wound of back wall of thorax	0.046	0.953	0.000
S21.1 Open wound of front wall of thorax	0.046	0.953	0.000
S21.0 Open wound of breast	0.046	0.953	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.046	0.953	0.000
S23.4 Sprain and strain of ribs and sternum	0.046	0.953	0.000
S23.3 Sprain and strain of thoracic spine	0.046	0.953	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.046	0.953	0.000
S23.1 Dislocation of thoracic vertebra	0.046	0.953	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.046	0.953	0.000
S24.6 Injury of unspecified nerve of thorax	0.046	0.953	0.000
S24.5 Injury of other nerves of thorax	0.046	0.953	0.000
S24.4 Injury of thoracic sympathetic nerves	0.046	0.953	0.000
S24.3 Injury of peripheral nerves of thorax	0.046	0.953	0.000
S24.2 Injury of nerve root of thoracic spine	0.046	0.953	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.046	0.953	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.046	0.953	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.046	0.953	0.000
S25.8 Injury of other blood vessels of thorax	0.046	0.953	0.000
S25.7 Injury of multiple blood vessels of thorax	0.046	0.953	0.000
S25.5 Injury of intercostal blood vessels	0.046	0.953	0.000
S25.4 Injury of pulmonary blood vessels	0.046	0.953	0.000
S25.3 Injury of innominate or subclavian vein	0.046	0.953	0.000
S25.2 Injury of superior vena cava	0.046	0.953	0.000
S25.1 Injury of innominate or subclavian artery	0.046	0.953	0.000
S25.0 Injury of thoracic aorta	0.046	0.953	0.000
S26.9 Injury of heart, unspecified	0.046	0.953	0.000
S26.8 Other injuries of heart	0.046	0.953	0.000
S26.0 Injury of heart with haemopericardium	0.046	0.953	0.000
S28.1 Traumatic amputation of part of thorax	0.046	0.953	0.000
S28.0 Crushed chest	0.046	0.953	0.000
S91 Open wound of ankle and foot	0.046	0.953	0.000
M79.62 Pain in limb (Upper arm)	0.046	0.954	0.000
M79.7 Fibromyalgia	0.046	0.954	0.000
T78.3 Angioneurotic oedema	0.046	0.954	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.045	0.954	0.001
M07 Psoriatic and enteropathic arthropathies	0.046	0.954	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.046	0.954	0.000
T98 Sequelae of other and unspecified effects of external causes	0.046	0.954	0.000
T95 Sequelae of burns, corrosions and frostbite	0.046	0.954	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.046	0.954	0.000
T91 Sequelae of injuries of neck and trunk	0.046	0.954	0.000
T90 Sequelae of injuries of head	0.046	0.954	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.046	0.954	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.046	0.954	0.000
M60-M63 Disorders of muscles	0.046	0.954	0.000
M00-M03 Infectious arthropathies	0.046	0.954	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.045	0.954	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.045	0.954	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.045	0.954	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.045	0.954	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.045	0.954	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.045	0.954	0.000
T82.3 Mechanical complication of other vascular grafts	0.045	0.954	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.045	0.954	0.000
T82.1 Mechanical complication of cardiac electronic device	0.045	0.954	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.045	0.954	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.045	0.955	0.000
S84.8 Injury of other nerves at lower leg level	0.045	0.955	0.000
S84.7 Injury of multiple nerves at lower leg level	0.045	0.955	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.045	0.955	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.045	0.955	0.000
S84.0 Injury of tibial nerve at lower leg level	0.045	0.955	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.045	0.955	0.000
S85.8 Injury of other blood vessels at lower leg level	0.045	0.955	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.045	0.955	0.000
S85.5 Injury of popliteal vein	0.045	0.955	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.045	0.955	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.045	0.955	0.000
S85.2 Injury of peroneal artery	0.045	0.955	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.045	0.955	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations