TreeWAS – Variant ID: rs185832426

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	0.178	0.822
I20-I25 Ischaemic heart diseases	0.169	0.831
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.168	0.832
I30-I52 Other forms of heart disease	0.164	0.836
I60-I69 Cerebrovascular diseases	0.159	0.841
I83 Varicose veins of lower extremities	0.153	0.847
I21 Acute myocardial infarction	0.152	0.848
I70-I79 Diseases of arteries, arterioles and capillaries	0.152	0.848
# Top node	0.150	0.850
Chapter II Neoplasms	0.149	0.851
I20 Angina pectoris	0.146	0.854
I84 Haemorrhoids	0.146	0.854
C43-C44 Melanoma and other malignant neoplasms of skin	0.142	0.858
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.142	0.858
I20.9 Angina pectoris, unspecified	0.140	0.860
C44 Other malignant neoplasms of skin	0.138	0.862
Chapter XII Diseases of the skin and subcutaneous tissue	0.138	0.862
I50 Heart failure	0.138	0.862
I34 Nonrheumatic mitral valve disorders	0.138	0.862
I82 Other venous embolism and thrombosis	0.136	0.863
I45 Other conduction disorders	0.136	0.864
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.136	0.864
Chapter IV Endocrine, nutritional and metabolic diseases	0.135	0.865
Chapter XV Pregnancy, childbirth and the puerperium	0.134	0.866
I84.8 Unspecified haemorrhoids with other complications	0.134	0.866
Chapter VII Diseases of the eye and adnexa	0.132	0.868
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.131	0.869
I78 Diseases of capillaries	0.130	0.870
I35 Nonrheumatic aortic valve disorders	0.130	0.870
I21.9 Acute myocardial infarction, unspecified	0.129	0.871
I63 Cerebral infarction	0.128	0.872
I05-I09 Chronic rheumatic heart diseases	0.128	0.872
I00-I02 Acute rheumatic fever	0.128	0.872
C44.3 Skin of other and unspecified parts of face	0.127	0.872
I21.0 Acute transmural myocardial infarction of anterior wall	0.127	0.873
Chapter XX External causes of morbidity and mortality	0.125	0.875
I25 Chronic ischaemic heart disease	0.125	0.875
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.125	0.875
I21.4 Acute subendocardial myocardial infarction	0.124	0.876
I67 Other cerebrovascular diseases	0.124	0.876
I64 Stroke, not specified as haemorrhage or infarction	0.123	0.877
I69 Sequelae of cerebrovascular disease	0.122	0.878
L40-L45 Papulosquamous disorders	0.122	0.878
I24 Other acute ischaemic heart diseases	0.121	0.879
I23 Certain current complications following acute myocardial infarction	0.121	0.879
I22 Subsequent myocardial infarction	0.121	0.879
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.121	0.879
I88 Nonspecific lymphadenitis	0.121	0.879
I87 Other disorders of veins	0.121	0.879
I86 Varicose veins of other sites	0.121	0.879
I85 Oesophageal varices	0.121	0.879
I81 Portal vein thrombosis	0.121	0.879
E10-E14 Diabetes mellitus	0.120	0.879
D10-D36 Benign neoplasms	0.120	0.880
L80-L99 Other disorders of the skin and subcutaneous tissue	0.120	0.880
I49 Other cardiac arrhythmias	0.119	0.881
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.118	0.882
I52 Other heart disorders in diseases classified elsewhere	0.118	0.882
I48 Atrial fibrillation and flutter	0.118	0.882
I46 Cardiac arrest	0.118	0.882
I43 Cardiomyopathy in diseases classified elsewhere	0.118	0.882
I42 Cardiomyopathy	0.118	0.882
I41 Myocarditis in diseases classified elsewhere	0.118	0.882
I40 Acute myocarditis	0.118	0.882
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.118	0.882
I37 Pulmonary valve disorders	0.118	0.882
I36 Nonrheumatic tricuspid valve disorders	0.118	0.882
I33 Acute and subacute endocarditis	0.118	0.882
I32 Pericarditis in diseases classified elsewhere	0.118	0.882
I31 Other diseases of pericardium	0.118	0.882
I30 Acute pericarditis	0.118	0.882
I38 Endocarditis, valve unspecified	0.118	0.882
O60-O75 Complications of labour and delivery	0.117	0.883
C44.5 Skin of trunk	0.116	0.884
I45.1 Other and unspecified right bundle-branch block	0.116	0.884
I77 Other disorders of arteries and arterioles	0.115	0.885
I78.1 Naevus, nonneoplastic	0.115	0.885
I95-I99 Other and unspecified disorders of the circulatory system	0.114	0.885
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.114	0.886
I68 Cerebrovascular disorders in diseases classified elsewhere	0.114	0.886
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.114	0.886
I62 Other nontraumatic intracranial haemorrhage	0.114	0.886
I61 Intracerebral haemorrhage	0.114	0.886
I60 Subarachnoid haemorrhage	0.114	0.886
I82.8 Embolism and thrombosis of other specified veins	0.114	0.886
C15-C26 Malignant neoplasms of digestive organs	0.114	0.886
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.113	0.887
I71 Aortic aneurysm and dissection	0.113	0.887
I34.0 Mitral (valve) insufficiency	0.113	0.887
D37-D48 Neoplasms of uncertain or unknown behaviour	0.113	0.887
I84.9 Unspecified haemorrhoids without complication	0.113	0.887
C44.4 Skin of scalp and neck	0.112	0.888
I50.1 Left ventricular failure	0.112	0.888
C64-C68 Malignant neoplasms of urinary tract	0.111	0.888
I84.2 Internal haemorrhoids without complication	0.111	0.889
I47 Paroxysmal tachycardia	0.111	0.889
L40 Psoriasis	0.110	0.890
I51 Complications and ill-defined descriptions of heart disease	0.110	0.890
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.110	0.890
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.110	0.890
I83.1 Varicose veins of lower extremities with inflammation	0.110	0.890
I83.0 Varicose veins of lower extremities with ulcer	0.110	0.890
I21.X Presumed acute myicardial infaction (unconfirmed)	0.109	0.890
I21.3 Acute transmural myocardial infarction of unspecified site	0.109	0.890
I21.2 Acute transmural myocardial infarction of other sites	0.109	0.890
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.109	0.890
I74 Arterial embolism and thrombosis	0.109	0.890
I72 Other aneurysm	0.109	0.890
I70 Atherosclerosis	0.109	0.890
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.109	0.891
I44 Atrioventricular and left bundle-branch block	0.109	0.891
C77.2 Intra-abdominal lymph nodes	0.109	0.891
D23 Other benign neoplasms of skin	0.109	0.891
C44.2 Skin of ear and external auricular canal	0.109	0.891
I50.0 Congestive heart failure	0.108	0.891
I73 Other peripheral vascular diseases	0.108	0.892
E65-E68 Obesity and other hyperalimentation	0.108	0.892
Chapter XXII Codes for special purposes	0.108	0.892
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.108	0.892
Chapter XVI Certain conditions originating in the perinatal period	0.108	0.892
I34.1 Mitral (valve) prolapse	0.107	0.892
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.107	0.893
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.107	0.893
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.107	0.893
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.107	0.893
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.107	0.893
C40-C41 Malignant neoplasms of bone and articular cartilage	0.107	0.893
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.107	0.893
Chapter VI Diseases of the nervous system	0.107	0.893
L82 Seborrhoeic keratosis	0.107	0.893
E50-E64 Other nutritional deficiencies	0.106	0.893
I63.9 Cerebral infarction, unspecified	0.106	0.894
I35.0 Aortic (valve) stenosis	0.106	0.894
I25.1 Atherosclerotic heart disease	0.106	0.894
C77.0 Lymph nodes of head, face and neck	0.105	0.895
E11 Non-insulin-dependent diabetes mellitus	0.105	0.895
I20.8 Other forms of angina pectoris	0.105	0.895
I20.1 Angina pectoris with documented spasm	0.105	0.895
I84.7 Unspecified thrombosed haemorrhoids	0.105	0.895
I84.5 External haemorrhoids without complication	0.105	0.895
I84.4 External haemorrhoids with other complications	0.105	0.895
I84.3 External thrombosed haemorrhoids	0.105	0.895
I84.0 Internal thrombosed haemorrhoids	0.105	0.895
I84.1 Internal haemorrhoids with other complications	0.105	0.895
D22 Melanocytic naevi	0.104	0.896
Chapter VIII Diseases of the ear and mastoid process	0.104	0.896
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.104	0.896
H43-H45 Disorders of vitreous body and globe	0.104	0.896
O80-O84 Delivery	0.104	0.896
D00-D09 In situ neoplasms	0.104	0.896
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.103	0.897
C51-C58 Malignant neoplasms of female genital organs	0.103	0.897
W00-W19 Falls	0.103	0.897
C43 Malignant melanoma of skin	0.102	0.898
I27 Other pulmonary heart diseases	0.102	0.898
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.102	0.898
O70 Perineal laceration during delivery	0.101	0.898
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.101	0.899
C77.5 Intrapelvic lymph nodes	0.101	0.899
I10-I15 Hypertensive diseases	0.101	0.899
I50.9 Heart failure, unspecified	0.101	0.899
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.100	0.900
L20-L30 Dermatitis and eczema	0.100	0.900
C60-C63 Malignant neoplasms of male genital organs	0.099	0.901
H00 Hordeolum and chalazion	0.099	0.901
C44.9 Malignant neoplasm of skin, unspecified	0.099	0.901
C44.8 Overlapping lesion of skin	0.099	0.901
C44.0 Skin of lip	0.099	0.901
L50-L54 Urticaria and erythema	0.099	0.901
L10-L14 Bullous disorders	0.099	0.901
L40.9 Psoriasis, unspecified	0.099	0.901
I67.9 Cerebrovascular disease, unspecified	0.099	0.901
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.099	0.901
I34.8 Other nonrheumatic mitral valve disorders	0.099	0.901
I34.2 Nonrheumatic mitral (valve) stenosis	0.099	0.901
C44.1 Skin of eyelid, including canthus	0.099	0.901
I82.9 Embolism and thrombosis of unspecified vein	0.098	0.902
I82.3 Embolism and thrombosis of renal vein	0.098	0.902
I82.2 Embolism and thrombosis of vena cava	0.098	0.902
I82.1 Thrombophlebitis migrans	0.098	0.902
I82.0 Budd-Chiari syndrome	0.098	0.902
I80 Phlebitis and thrombophlebitis	0.098	0.902
I45.9 Conduction disorder, unspecified	0.098	0.902
I45.8 Other specified conduction disorders	0.098	0.902
I45.6 Preexcitation syndrome	0.098	0.902
I45.5 Other specified heart block	0.098	0.902
I45.4 Nonspecific intraventricular block	0.098	0.902
I45.3 Trifascicular block	0.098	0.902
I45.2 Bifascicular block	0.098	0.902
I45.0 Right fascicular block	0.098	0.902
C80 Malignant neoplasm without specification of site	0.098	0.902
C76 Malignant neoplasm of other and ill-defined sites	0.098	0.902
O94-O99 Other obstetric conditions, not elsewhere classified	0.097	0.902
Chapter I Certain infectious and parasitic diseases	0.097	0.903
E40-E46 Malnutrition	0.097	0.903
E20-E35 Disorders of other endocrine glands	0.097	0.903
D11 Benign neoplasm of major salivary glands	0.097	0.903
H30-H36 Disorders of choroid and retina	0.097	0.903
H53-H54 Visual disturbances and blindness	0.097	0.903
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.096	0.903
O85-O92 Complications predominantly related to the puerperium	0.096	0.903
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.096	0.903
O00-O08 Pregnancy with abortive outcome	0.096	0.903
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.096	0.904
I21.1 Acute transmural myocardial infarction of inferior wall	0.096	0.904
O68 Labour and delivery complicated by foetal stress [distress]	0.096	0.904
C44.7 Skin of lower limb, including hip	0.095	0.904
H55-H59 Other disorders of eye and adnexa	0.095	0.905
H46-H48 Disorders of optic nerve and visual pathways	0.095	0.905
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.095	0.905
H10-H13 Disorders of conjunctiva	0.095	0.905
L60-L75 Disorders of skin appendages	0.095	0.905
O20-O29 Other maternal disorders predominantly related to pregnancy	0.095	0.905
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.095	0.905
E14 Unspecified diabetes mellitus	0.095	0.905
I28 Other diseases of pulmonary vessels	0.094	0.906
L00-L08 Infections of the skin and subcutaneous tissue	0.094	0.906
D23.3 Skin of other and unspecified parts of face	0.094	0.906
I78.9 Disease of capillaries, unspecified	0.094	0.906
I78.8 Other diseases of capillaries	0.094	0.906
I78.0 Hereditary haemorrhagic telangiectasia	0.094	0.906
C78.7 Secondary malignant neoplasm of liver	0.094	0.906
I35.9 Aortic valve disorder, unspecified	0.093	0.906
I35.8 Other aortic valve disorders	0.093	0.906
I35.2 Aortic (valve) stenosis with insufficiency	0.093	0.906
I35.1 Aortic (valve) insufficiency	0.093	0.906
D24 Benign neoplasm of breast	0.093	0.906
C44.6 Skin of upper limb, including shoulder	0.093	0.906
E11.9 Without complications	0.093	0.907
C50-C50 Malignant neoplasm of breast	0.093	0.907
H40-H42 Glaucoma	0.093	0.907
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.093	0.907
L91 Hypertrophic disorders of skin	0.093	0.907
D22.3 Melanocytic naevi of other and unspecified parts of face	0.093	0.907
C77.1 Intrathoracic lymph nodes	0.092	0.907
L81 Other disorders of pigmentation	0.092	0.908
E16 Other disorders of pancreatic internal secretion	0.092	0.908
I63.8 Other cerebral infarction	0.092	0.908
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.092	0.908
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.092	0.908
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.092	0.908
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.092	0.908
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.092	0.908
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.092	0.908
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.092	0.908
I02 Rheumatic chorea	0.092	0.908
I01 Rheumatic fever with heart involvement	0.092	0.908
I00 Rheumatic fever without mention of heart involvement	0.092	0.908
I09 Other rheumatic heart diseases	0.092	0.908
I08 Multiple valve diseases	0.092	0.908
I07 Rheumatic tricuspid valve diseases	0.092	0.908
I06 Rheumatic aortic valve diseases	0.092	0.908
I05 Rheumatic mitral valve diseases	0.092	0.908
L97 Ulcer of lower limb, not elsewhere classified	0.091	0.909
S70-S79 Injuries to the hip and thigh	0.090	0.909
E10 Insulin-dependent diabetes mellitus	0.090	0.910
O70.1 Second degree perineal laceration during delivery	0.090	0.910
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.090	0.910
Y60-Y69 Misadventures to patients during surgical and medical care	0.090	0.910
Y35-Y36 Legal intervention and operations of war	0.090	0.910
Y10-Y34 Event of undetermined intent	0.090	0.910
Y00-Y09 Assault	0.090	0.910
X85-X99 Assault	0.090	0.910
X60-X84 Intentional self-harm	0.090	0.910
X58-X59 Accidental exposure to other and unspecified factors	0.090	0.910
X50-X57 Overexertion, travel and privation	0.090	0.910
X40-X49 Accidental poisoning by and exposure to noxious substances	0.090	0.910
X30-X39 Exposure to forces of nature	0.090	0.910
X20-X29 Contact with venomous animals and plants	0.090	0.910
X10-X19 Contact with heat and hot substances	0.090	0.910
X00-X09 Exposure to smoke, fire and flames	0.090	0.910
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.090	0.910
W75-W84 Other accidental threats to breathing	0.090	0.910
W65-W74 Accidental drowning and submersion	0.090	0.910
W50-W64 Exposure to animate mechanical forces	0.090	0.910
W20-W49 Exposure to inanimate mechanical forces	0.090	0.910
V98-V99 Other and unspecified transport accidents	0.090	0.910
V95-V97 Air and space transport accidents	0.090	0.910
V90-V94 Water transport accidents	0.090	0.910
V80-V89 Other land transport accidents	0.090	0.910
V70-V79 Bus occupant injured in transport accident	0.090	0.910
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.090	0.910
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.090	0.910
V40-V49 Car occupant injured in transport accident	0.090	0.910
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.090	0.910
V20-V29 Motorcycle rider injured in transport accident	0.090	0.910
V10-V19 Pedal cyclist injured in transport accident	0.090	0.910
V01-V09 Pedestrian injured in transport accident	0.090	0.910
I25.6 Silent myocardial ischaemia	0.090	0.910
I25.5 Ischaemic cardiomyopathy	0.090	0.910
I25.4 Coronary artery aneurysm	0.090	0.910
I25.3 Aneurysm of heart	0.090	0.910
I25.0 Atherosclerotic cardiovascular disease, so described	0.090	0.910
C18 Malignant neoplasm of colon	0.090	0.910
C77.9 Lymph node, unspecified	0.090	0.910
C77.8 Lymph nodes of multiple regions	0.090	0.910
C77.4 Inguinal and lower limb lymph nodes	0.090	0.910
D23.5 Skin of trunk	0.090	0.910
E00-E07 Disorders of thyroid gland	0.090	0.910
I26 Pulmonary embolism	0.089	0.911
H00.1 Chalazion	0.089	0.911
I67.8 Other specified cerebrovascular diseases	0.089	0.911
I67.7 Cerebral arteritis, not elsewhere classified	0.089	0.911
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.089	0.911
I67.5 Moyamoya disease	0.089	0.911
I67.4 Hypertensive encephalopathy	0.089	0.911
I67.3 Progressive vascular leukoencephalopathy	0.089	0.911
I67.2 Cerebral atherosclerosis	0.089	0.911
I67.1 Cerebral aneurysm, nonruptured	0.089	0.911
I67.0 Dissection of cerebral arteries, nonruptured	0.089	0.911
H25-H28 Disorders of lens	0.089	0.911
I65.2 Occlusion and stenosis of carotid artery	0.088	0.911
E66 Obesity	0.088	0.911
C79 Secondary malignant neoplasm of other sites	0.088	0.912
I77.1 Stricture of artery	0.088	0.912
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.088	0.912
I69.3 Sequelae of cerebral infarction	0.088	0.912
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.088	0.912
I69.1 Sequelae of intracerebral haemorrhage	0.088	0.912
I69.0 Sequelae of subarachnoid haemorrhage	0.088	0.912
L40.5 Arthropathic psoriasis	0.088	0.912
L44 Other papulosquamous disorders	0.087	0.912
L43 Lichen planus	0.087	0.912
L41 Parapsoriasis	0.087	0.912
L45 Papulosquamous disorders in diseases classified elsewhere	0.087	0.912
L42 Pityriasis rosea	0.087	0.912
I49.9 Cardiac arrhythmia, unspecified	0.087	0.912
I25.8 Other forms of chronic ischaemic heart disease	0.087	0.913
I22.9 Subsequent myocardial infarction of unspecified site	0.087	0.913
I22.8 Subsequent myocardial infarction of other sites	0.087	0.913
I22.1 Subsequent myocardial infarction of inferior wall	0.087	0.913
I22.0 Subsequent myocardial infarction of anterior wall	0.087	0.913
I23.8 Other current complications following acute myocardial infarction	0.087	0.913
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.087	0.913
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.087	0.913
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.087	0.913
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.087	0.913
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.087	0.913
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.087	0.913
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.087	0.913
I24.9 Acute ischaemic heart disease, unspecified	0.087	0.913
I24.8 Other forms of acute ischaemic heart disease	0.087	0.913
I24.1 Dressler's syndrome	0.087	0.913
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.087	0.913
I85.9 Oesophageal varices without bleeding	0.087	0.913
I85.0 Oesophageal varices with bleeding	0.087	0.913
I86.8 Varicose veins of other specified sites	0.087	0.913
I86.4 Gastric varices	0.087	0.913
I86.3 Vulval varices	0.087	0.913
I86.2 Pelvic varices	0.087	0.913
I86.1 Scrotal varices	0.087	0.913
I86.0 Sublingual varices	0.087	0.913
I87.9 Disorder of vein, unspecified	0.087	0.913
I87.8 Other specified disorders of veins	0.087	0.913
I87.2 Venous insufficiency (chronic) (peripheral)	0.087	0.913
I87.1 Compression of vein	0.087	0.913
I87.0 Postphlebitic syndrome	0.087	0.913
I88.9 Nonspecific lymphadenitis, unspecified	0.087	0.913
I88.8 Other nonspecific lymphadenitis	0.087	0.913
I88.1 Chronic lymphadenitis, except mesenteric	0.087	0.913
I88.0 Nonspecific mesenteric lymphadenitis	0.087	0.913
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.087	0.913
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.087	0.913
I89.1 Lymphangitis	0.087	0.913
I89.0 Lymphoedema, not elsewhere classified	0.087	0.913
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.087	0.913
E13 Other specified diabetes mellitus	0.086	0.913
E12 Malnutrition-related diabetes mellitus	0.086	0.913
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.086	0.913
D36 Benign neoplasm of other and unspecified sites	0.086	0.914
D35 Benign neoplasm of other and unspecified endocrine glands	0.086	0.914
D33 Benign neoplasm of brain and other parts of central nervous system	0.086	0.914
D32 Benign neoplasm of meninges	0.086	0.914
D31 Benign neoplasm of eye and adnexa	0.086	0.914
D30 Benign neoplasm of urinary organs	0.086	0.914
D29 Benign neoplasm of male genital organs	0.086	0.914
D28 Benign neoplasm of other and unspecified female genital organs	0.086	0.914
D26 Other benign neoplasms of uterus	0.086	0.914
D21 Other benign neoplasms of connective and other soft tissue	0.086	0.914
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.086	0.914
D19 Benign neoplasm of mesothelial tissue	0.086	0.914
D16 Benign neoplasm of bone and articular cartilage	0.086	0.914
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.086	0.914
D14 Benign neoplasm of middle ear and respiratory system	0.086	0.914
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.086	0.914
D10 Benign neoplasm of mouth and pharynx	0.086	0.914
D34 Benign neoplasm of thyroid gland	0.086	0.914
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.086	0.914
L95 Vasculitis limited to skin, not elsewhere classified	0.086	0.914
L94 Other localised connective tissue disorders	0.086	0.914
L93 Lupus erythematosus	0.086	0.914
L92 Granulomatous disorders of skin and subcutaneous tissue	0.086	0.914
L89 Decubitus ulcer	0.086	0.914
L87 Transepidermal elimination disorders	0.086	0.914
L85 Other epidermal thickening	0.086	0.914
L88 Pyoderma gangrenosum	0.086	0.914
L86 Keratoderma in diseases classified elsewhere	0.086	0.914
L84 Corns and callosities	0.086	0.914
L83 Acanthosis nigricans	0.086	0.914
L80 Vitiligo	0.086	0.914
W19 Unspecified fall	0.086	0.914
E55 Vitamin D deficiency	0.086	0.914
C64 Malignant neoplasm of kidney, except renal pelvis	0.086	0.914
I49.8 Other specified cardiac arrhythmias	0.086	0.914
I49.5 Sick sinus syndrome	0.086	0.914
I49.4 Other and unspecified premature depolarisation	0.086	0.914
I49.3 Ventricular premature depolarisation	0.086	0.914
I49.2 Junctional premature depolarisation	0.086	0.914
I49.1 Atrial premature depolarisation	0.086	0.914
I49.0 Ventricular fibrillation and flutter	0.086	0.914
I25.9 Chronic ischaemic heart disease, unspecified	0.086	0.914
S80-S89 Injuries to the knee and lower leg	0.085	0.915
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.085	0.915
C19 Malignant neoplasm of rectosigmoid junction	0.085	0.915
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.085	0.915
I65.8 Occlusion and stenosis of other precerebral artery	0.085	0.915
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.085	0.915
I65.1 Occlusion and stenosis of basilar artery	0.085	0.915
I65.0 Occlusion and stenosis of vertebral artery	0.085	0.915
I30.9 Acute pericarditis, unspecified	0.084	0.915
I30.8 Other forms of acute pericarditis	0.084	0.915
I30.1 Infective pericarditis	0.084	0.915
I30.0 Acute nonspecific idiopathic pericarditis	0.084	0.915
I31.9 Disease of pericardium, unspecified	0.084	0.915
I31.8 Other specified diseases of pericardium	0.084	0.915
I31.3 Pericardial effusion (noninflammatory)	0.084	0.915
I31.2 Haemopericardium, not elsewhere classified	0.084	0.915
I31.1 Chronic constrictive pericarditis	0.084	0.915
I31.0 Chronic adhesive pericarditis	0.084	0.915
I32.8 Pericarditis in other diseases classified elsewhere	0.084	0.915
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.084	0.915
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.084	0.915
I33.9 Acute endocarditis, unspecified	0.084	0.915
I33.0 Acute and subacute infective endocarditis	0.084	0.915
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.084	0.915
I36.8 Other nonrheumatic tricuspid valve disorders	0.084	0.915
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.084	0.915
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.084	0.915
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.084	0.915
I37.9 Pulmonary valve disorder, unspecified	0.084	0.915
I37.8 Other pulmonary valve disorders	0.084	0.915
I37.2 Pulmonary valve stenosis with insufficiency	0.084	0.915
I37.1 Pulmonary valve insufficiency	0.084	0.915
I37.0 Pulmonary valve stenosis	0.084	0.915
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.084	0.915
I39.4 Multiple valve disorders in diseases classified elsewhere	0.084	0.915
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.084	0.915
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.084	0.915
I39.1 Aortic valve disorders in diseases classified elsewhere	0.084	0.915
I39.0 Mitral valve disorders in diseases classified elsewhere	0.084	0.915
I40.9 Acute myocarditis, unspecified	0.084	0.915
I40.8 Other acute myocarditis	0.084	0.915
I40.1 Isolated myocarditis	0.084	0.915
I40.0 Infective myocarditis	0.084	0.915
I41.8 Myocarditis in other diseases classified elsewhere	0.084	0.915
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.084	0.915
I41.1 Myocarditis in viral diseases classified elsewhere	0.084	0.915
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.084	0.915
I42.9 Cardiomyopathy, unspecified	0.084	0.915
I42.8 Other cardiomyopathies	0.084	0.915
I42.7 Cardiomyopathy due to drugs and other external agents	0.084	0.915
I42.6 Alcoholic cardiomyopathy	0.084	0.915
I42.5 Other restrictive cardiomyopathy	0.084	0.915
I42.4 Endocardial fibroelastosis	0.084	0.915
I42.3 Endomyocardial (eosinophilic) disease	0.084	0.915
I42.2 Other hypertrophic cardiomyopathy	0.084	0.915
I42.1 Obstructive hypertrophic cardiomyopathy	0.084	0.915
I42.0 Dilated cardiomyopathy	0.084	0.915
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.084	0.915
I43.2 Cardiomyopathy in nutritional diseases	0.084	0.915
I43.1 Cardiomyopathy in metabolic diseases	0.084	0.915
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.084	0.915
I46.9 Cardiac arrest, unspecified	0.084	0.915
I46.1 Sudden cardiac death, so described	0.084	0.915
I46.0 Cardiac arrest with successful resuscitation	0.084	0.915
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.084	0.915
I48.4 Atypical atrial flutter	0.084	0.915
I48.3 Typical atrial flutter	0.084	0.915
I48.2 Chronic atrial fibrillation	0.084	0.915
I48.1 Persistent atrial fibrillation	0.084	0.915
I48.0 Paroxysmal atrial fibrillation	0.084	0.915
I52.8 Other heart disorders in other diseases classified elsewhere	0.084	0.915
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.084	0.915
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.084	0.915
G80-G83 Cerebral palsy and other paralytic syndromes	0.084	0.916
O75 Other complications of labour and delivery, not elsewhere classified	0.084	0.916
O74 Complications of anaesthesia during labour and delivery	0.084	0.916
O73 Retained placenta and membranes, without haemorrhage	0.084	0.916
O71 Other obstetric trauma	0.084	0.916
O69 Labour and delivery complicated by umbilical cord complications	0.084	0.916
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.084	0.916
O66 Other obstructed labour	0.084	0.916
O65 Obstructed labour due to maternal pelvic abnormality	0.084	0.916
O64 Obstructed labour due to malposition and malpresentation of foetus	0.084	0.916
O62 Abnormalities of forces of labour	0.084	0.916
O61 Failed induction of labour	0.084	0.916
O60 Preterm delivery	0.084	0.916
O72 Postpartum haemorrhage	0.084	0.916
H02 Other disorders of eyelid	0.084	0.916
H43 Disorders of vitreous body	0.083	0.916

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations