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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1889142
log Bayes Factor = 8.91929
Chromosome 20   position 45,608,700  (GRCh37) Explore rs1889142 on Ensembl!
Variant rs1889142 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
E10 Insulin-dependent diabetes mellitus
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
S00-S09 Injuries to the head
0.991 0.009 0.000
H04 Disorders of lachrymal system
0.991 0.009 0.000
E10.9 Without complications
0.989 0.011 0.000
S01 Open wound of head
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
E20-E35 Disorders of other endocrine glands
0.980 0.020 0.000
Chapter XI Diseases of the digestive system
0.976 0.024 0.000
I73 Other peripheral vascular diseases
0.975 0.025 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.972 0.028 0.000
H02 Other disorders of eyelid
0.968 0.032 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.961 0.039 0.000
H65-H75 Diseases of middle ear and mastoid
0.958 0.042 0.000
I71 Aortic aneurysm and dissection
0.949 0.051 0.000
I73.9 Peripheral vascular disease, unspecified
0.946 0.054 0.000
E11 Non-insulin-dependent diabetes mellitus
0.945 0.055 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.938 0.062 0.000
K70-K77 Diseases of liver
0.937 0.063 0.000
I74 Arterial embolism and thrombosis
0.937 0.063 0.000
K08 Other disorders of teeth and supporting structures
0.933 0.067 0.000
H90-H95 Other disorders of ear
0.932 0.068 0.000
S01.0 Open wound of scalp
0.931 0.069 0.000
H65 Nonsuppurative otitis media
0.931 0.069 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.929 0.071 0.000
W20-W49 Exposure to inanimate mechanical forces
0.924 0.076 0.000
H04.2 Epiphora
0.918 0.082 0.000
E00-E07 Disorders of thyroid gland
0.918 0.082 0.000
H65.3 Chronic mucoid otitis media
0.915 0.085 0.000
H04.1 Other disorders of lachrymal gland
0.915 0.085 0.000
K65-K67 Diseases of peritoneum
0.912 0.088 0.000
H80-H83 Diseases of inner ear
0.911 0.089 0.000
H02.5 Other disorders affecting eyelid function
0.908 0.092 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.901 0.099 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.900 0.100 0.000
K13 Other diseases of lip and oral mucosa
0.899 0.101 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.899 0.101 0.000
K75 Other inflammatory liver diseases
0.898 0.102 0.000
S50-S59 Injuries to the elbow and forearm
0.894 0.106 0.000
K02 Dental caries
0.889 0.111 0.000
S01.8 Open wound of other parts of head
0.887 0.113 0.000
K08.3 Retained dental root
0.884 0.116 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.881 0.119 0.000
H40-H42 Glaucoma
0.880 0.120 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.879 0.121 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.879 0.121 0.000
H81 Disorders of vestibular function
0.878 0.122 0.000
S01.2 Open wound of nose
0.877 0.123 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.877 0.123 0.000
I85 Oesophageal varices
0.874 0.126 0.000
H02.1 Ectropion of eyelid
0.873 0.127 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.860 0.140 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.859 0.141 0.000
I85.9 Oesophageal varices without bleeding
0.856 0.144 0.000
E29 Testicular dysfunction
0.855 0.145 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.853 0.147 0.000
E40-E46 Malnutrition
0.851 0.149 0.000
K75.9 Inflammatory liver disease, unspecified
0.850 0.150 0.000
E27 Other disorders of adrenal gland
0.849 0.151 0.000
H72 Perforation of tympanic membrane
0.849 0.151 0.000
H30-H36 Disorders of choroid and retina
0.847 0.153 0.000
I73.0 Raynaud's syndrome
0.844 0.155 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.844 0.156 0.000
E23 Hypofunction and other disorders of pituitary gland
0.841 0.159 0.000
W22 Striking against or struck by other objects
0.840 0.160 0.000
I72 Other aneurysm
0.838 0.161 0.000
S52 Fracture of forearm
0.838 0.162 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.836 0.164 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.831 0.169 0.000
K11 Diseases of salivary glands
0.830 0.170 0.000
Y43 Primarily systemic agents
0.828 0.172 0.000
I77 Other disorders of arteries and arterioles
0.827 0.173 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.827 0.173 0.000
K02.9 Dental caries, unspecified
0.826 0.174 0.000
S06 Intracranial injury
0.821 0.179 0.000
K74 Fibrosis and cirrhosis of liver
0.818 0.182 0.000
S60-S69 Injuries to the wrist and hand
0.816 0.184 0.000
E10.1 With ketoacidosis
0.815 0.185 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.815 0.185 0.000
H81.0 Meniere's disease
0.813 0.187 0.000
H90 Conductive and sensorineural hearing loss
0.813 0.187 0.000
K66 Other disorders of peritoneum
0.809 0.191 0.000
L20-L30 Dermatitis and eczema
0.808 0.192 0.000
E10.3 With ophthalmic complications
0.807 0.193 0.000
H43-H45 Disorders of vitreous body and globe
0.806 0.194 0.000
W25 Contact with sharp glass
0.806 0.194 0.000
K65 Peritonitis
0.800 0.200 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.800 0.200 0.000
H93 Other disorders of ear, not elsewhere classified
0.799 0.201 0.000
I74.5 Embolism and thrombosis of iliac artery
0.795 0.205 0.000
H40 Glaucoma
0.794 0.206 0.000
L85 Other epidermal thickening
0.793 0.207 0.000
E11.2 With renal complications
0.793 0.207 0.000
H04.4 Chronic inflammation of lachrymal passages
0.792 0.208 0.000
T93 Sequelae of injuries of lower limb
0.792 0.208 0.000
H36 Retinal disorders in diseases classified elsewhere
0.789 0.211 0.000
K14 Diseases of tongue
0.789 0.211 0.000
E24 Cushing's syndrome
0.788 0.212 0.000
E11.5 With peripheral circulatory complications
0.787 0.212 0.000
H81.1 Benign paroxysmal vertigo
0.786 0.214 0.000
L50-L54 Urticaria and erythema
0.785 0.215 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.785 0.215 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.785 0.215 0.000
E26 Hyperaldosteronism
0.785 0.215 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.782 0.218 0.000
H02.3 Blepharochalasis
0.781 0.219 0.000
W22.9 Unspecified place
0.780 0.220 0.000
E11.9 Without complications
0.778 0.222 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.778 0.222 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.778 0.222 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
E05.9 Thyrotoxicosis, unspecified
0.776 0.224 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.775 0.225 0.000
Q60-Q64 Congenital malformations of the urinary system
0.773 0.227 0.000
Y57 Other and unspecified drugs and medicaments
0.773 0.227 0.000
I87 Other disorders of veins
0.772 0.228 0.000
H72.0 Central perforation of tympanic membrane
0.771 0.229 0.000
S90-S99 Injuries to the ankle and foot
0.770 0.230 0.000
L84 Corns and callosities
0.769 0.231 0.000
E20 Hypoparathyroidism
0.768 0.232 0.000
H01 Other inflammation of eyelid
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
S52.6 Fracture of lower end of both ulna and radius
0.766 0.234 0.000
E29.1 Testicular hypofunction
0.766 0.234 0.000
H65.4 Other chronic nonsuppurative otitis media
0.765 0.234 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.765 0.235 0.000
H02.9 Disorder of eyelid, unspecified
0.764 0.236 0.000
K07 Dentofacial anomalies [including malocclusion]
0.763 0.236 0.000
E10.4 With neurological complications
0.762 0.238 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.761 0.239 0.000
E11.3 With ophthalmic complications
0.760 0.240 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.759 0.241 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.755 0.245 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.755 0.245 0.000
X50-X57 Overexertion, travel and privation
0.754 0.245 0.000
L85.9 Epidermal thickening, unspecified
0.754 0.246 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.751 0.249 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.750 0.250 0.000
S01.5 Open wound of lip and oral cavity
0.750 0.250 0.000
Y43.4 Immunosuppressive agents
0.749 0.251 0.000
K35-K38 Diseases of appendix
0.749 0.251 0.000
H36.0 Diabetic retinopathy
0.748 0.252 0.000
K00 Disorders of tooth development and eruption
0.748 0.252 0.000
I71.0 Dissection of aorta [any part]
0.746 0.254 0.000
S01.1 Open wound of eyelid and periocular area
0.745 0.255 0.000
E46 Unspecified protein-energy malnutrition
0.744 0.256 0.000
E22 Hyperfunction of pituitary gland
0.743 0.257 0.000
L40-L45 Papulosquamous disorders
0.742 0.257 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
W50-W64 Exposure to animate mechanical forces
0.742 0.258 0.000
S01.3 Open wound of ear
0.742 0.258 0.000
E23.0 Hypopituitarism
0.742 0.258 0.000
S00 Superficial injury of head
0.741 0.259 0.000
I10-I15 Hypertensive diseases
0.740 0.260 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.738 0.261 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.738 0.262 0.000
H40.2 Primary angle-closure glaucoma
0.737 0.263 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.737 0.263 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.736 0.263 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.734 0.266 0.000
K66.0 Peritoneal adhesions
0.730 0.270 0.000
I05-I09 Chronic rheumatic heart diseases
0.727 0.273 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.726 0.274 0.000
L03 Cellulitis
0.726 0.274 0.000
H44 Disorders of globe
0.724 0.276 0.000
V40-V49 Car occupant injured in transport accident
0.723 0.277 0.000
T90 Sequelae of injuries of head
0.722 0.278 0.000
T66-T78 Other and unspecified effects of external causes
0.722 0.278 0.000
W25.9 Unspecified place
0.721 0.279 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.721 0.279 0.000
H92 Otalgia and effusion of ear
0.718 0.282 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H05 Disorders of orbit
0.716 0.284 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.716 0.284 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
K01 Embedded and impacted teeth
0.715 0.285 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.715 0.285 0.000
S52.1 Fracture of upper end of radius
0.715 0.285 0.000
E10.8 With unspecified complications
0.713 0.287 0.000
E10.7 With multiple complications
0.713 0.287 0.000
E10.6 With other specified complications
0.713 0.287 0.000
E10.2 With renal complications
0.713 0.287 0.000
E10.0 With coma
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.712 0.287 0.000
S40-S49 Injuries to the shoulder and upper arm
0.712 0.288 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.712 0.288 0.000
K75.0 Abscess of liver
0.712 0.288 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.711 0.289 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
H04.9 Disorder of lachrymal system, unspecified
0.710 0.290 0.000
H04.8 Other disorders of lachrymal system
0.710 0.290 0.000
H04.6 Other changes in lachrymal passages
0.710 0.290 0.000
H04.0 Dacryoadenitis
0.710 0.290 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.710 0.290 0.000
S09 Other and unspecified injuries of head
0.710 0.290 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.710 0.290 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.710 0.290 0.000
H40.1 Primary open-angle glaucoma
0.709 0.291 0.000
K75.4 Autoimmune hepatitis
0.708 0.292 0.000
H69 Other disorders of Eustachian tube
0.707 0.293 0.000
K09 Cysts of oral region, not elsewhere classified
0.706 0.294 0.000
S01.7 Multiple open wounds of head
0.705 0.295 0.000
S01.4 Open wound of cheek and temporomandibular area
0.705 0.295 0.000
W44 Foreign body entering into or through eye or natural orifice
0.705 0.295 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.705 0.295 0.000
Q80-Q89 Other congenital malformations
0.704 0.296 0.000
H93.1 Tinnitus
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.702 0.298 0.000
E34 Other endocrine disorders
0.702 0.298 0.000
E32 Diseases of thymus
0.702 0.298 0.000
E31 Polyglandular dysfunction
0.702 0.298 0.000
E30 Disorders of puberty, not elsewhere classified
0.702 0.298 0.000
E25 Adrenogenital disorders
0.702 0.298 0.000
H74 Other disorders of middle ear and mastoid
0.702 0.298 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.701 0.298 0.000
W00-W19 Falls
0.701 0.299 0.000
I70 Atherosclerosis
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.700 0.300 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.700 0.300 0.000
I73.8 Other specified peripheral vascular diseases
0.699 0.301 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.699 0.301 0.000
I72.3 Aneurysm of iliac artery
0.698 0.302 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
S10-S19 Injuries to the neck
0.697 0.302 0.000
E10.5 With peripheral circulatory complications
0.697 0.303 0.000
Q50-Q56 Congenital malformations of genital organs
0.697 0.303 0.000
K03 Other diseases of hard tissues of teeth
0.697 0.303 0.000
H02.4 Ptosis of eyelid
0.696 0.303 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.695 0.305 0.000
T86 Failure and rejection of transplanted organs and tissues
0.695 0.305 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.694 0.306 0.000
H02.2 Lagophthalmos
0.694 0.306 0.000
X60-X84 Intentional self-harm
0.694 0.306 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.694 0.306 0.000
I81 Portal vein thrombosis
0.694 0.306 0.000
E11.0 With coma
0.693 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.691 0.309 0.000
H18 Other disorders of cornea
0.690 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.689 0.311 0.000
L10-L14 Bullous disorders
0.689 0.311 0.000
H91 Other hearing loss
0.687 0.313 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.687 0.313 0.000
H70 Mastoiditis and related conditions
0.687 0.313 0.000
H68 Eustachian salpingitis and obstruction
0.687 0.313 0.000
H67 Otitis media in diseases classified elsewhere
0.687 0.313 0.000
K11.2 Sialoadenitis
0.685 0.315 0.000
L27 Dermatitis due to substances taken internally
0.685 0.315 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.684 0.316 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.683 0.317 0.000
K65.8 Other peritonitis
0.683 0.317 0.000
I12 Hypertensive renal disease
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.680 0.319 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.680 0.320 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.680 0.320 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.680 0.320 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.680 0.320 0.000
E27.8 Other specified disorders of adrenal gland
0.679 0.320 0.000
K72 Hepatic failure, not elsewhere classified
0.678 0.322 0.000
E11.8 With unspecified complications
0.678 0.322 0.000
E11.7 With multiple complications
0.678 0.322 0.000
E11.6 With other specified complications
0.678 0.322 0.000
E11.1 With ketoacidosis
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.677 0.323 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.675 0.325 0.000
K74.3 Primary biliary cirrhosis
0.675 0.325 0.000
K14.0 Glossitis
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.673 0.327 0.000
Y44 Agents primarily affecting blood constituents
0.673 0.327 0.000
T87 Complications peculiar to reattachment and amputation
0.673 0.327 0.000
H31 Other disorders of choroid
0.672 0.328 0.000
K77 Liver disorders in diseases classified elsewhere
0.672 0.328 0.000
K73 Chronic hepatitis, not elsewhere classified
0.672 0.328 0.000
K71 Toxic liver disease
0.672 0.328 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.671 0.328 0.000
I74.8 Embolism and thrombosis of other arteries
0.671 0.328 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.671 0.328 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.671 0.328 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.671 0.328 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.671 0.328 0.000
L43 Lichen planus
0.671 0.329 0.000
E11.4 With neurological complications
0.671 0.329 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.670 0.330 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.669 0.331 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.668 0.332 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.668 0.332 0.000
H65.2 Chronic serous otitis media
0.667 0.332 0.000
H65.1 Other acute nonsuppurative otitis media
0.667 0.332 0.000
H65.0 Acute serous otitis media
0.667 0.332 0.000
L94 Other localised connective tissue disorders
0.667 0.333 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.667 0.333 0.000
I77.6 Arteritis, unspecified
0.666 0.334 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.666 0.334 0.000
Q35-Q37 Cleft lip and cleft palate
0.666 0.334 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.666 0.334 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
H53-H54 Visual disturbances and blindness
0.665 0.335 0.000
S52.0 Fracture of upper end of ulna
0.665 0.335 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.665 0.335 0.000
H72.8 Other perforations of tympanic membrane
0.664 0.336 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.664 0.336 0.000
E70-E90 Metabolic disorders
0.663 0.337 0.000
W46 Contact with hypodermic needle
0.662 0.338 0.000
W45 Foreign body or object entering through skin
0.662 0.338 0.000
W43 Exposure to vibration
0.662 0.338 0.000
W42 Exposure to noise
0.662 0.338 0.000
W41 Exposure to high-pressure jet
0.662 0.338 0.000
W40 Explosion of other materials
0.662 0.338 0.000
W39 Discharge of firework
0.662 0.338 0.000
W38 Explosion and rupture of other specified pressurised devices
0.662 0.338 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.662 0.338 0.000
W36 Explosion and rupture of gas cylinder
0.662 0.338 0.000
W35 Explosion and rupture of boiler
0.662 0.338 0.000
W34 Discharge from other and unspecified firearms
0.662 0.338 0.000
W33 Rifle, shotgun and larger firearm discharge
0.662 0.338 0.000
W32 Handgun discharge
0.662 0.338 0.000
W31 Contact with other and unspecified machinery
0.662 0.338 0.000
W30 Contact with agricultural machinery
0.662 0.338 0.000
W28 Contact with powered lawn mower
0.662 0.338 0.000
W27 Contact with nonpowered hand tool
0.662 0.338 0.000
W26 Contact with knife, sword or dagger
0.662 0.338 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.662 0.338 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.662 0.338 0.000
W21 Striking against or struck by sports equipment
0.662 0.338 0.000
W20 Struck by thrown, projected or falling object
0.662 0.338 0.000
L03.1 Cellulitis of other parts of limb
0.661 0.339 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.661 0.339 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.660 0.339 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.660 0.340 0.000
T92 Sequelae of injuries of upper limb
0.659 0.341 0.000
K10 Other diseases of jaws
0.658 0.342 0.000
H16 Keratitis
0.658 0.342 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.658 0.342 0.000
E00 Congenital iodine-deficiency syndrome
0.658 0.342 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.658 0.342 0.000
L50 Urticaria
0.657 0.343 0.000
H44.2 Degenerative myopia
0.656 0.344 0.000
Chapter VI Diseases of the nervous system
0.656 0.344 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.654 0.346 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.653 0.347 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.653 0.347 0.000
K02.8 Other dental caries
0.653 0.347 0.000
E24.2 Drug-induced Cushing's syndrome
0.652 0.347 0.000
S01.9 Open wound of head, part unspecified
0.651 0.349 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.651 0.349 0.000
Y40 Systemic antibiotics
0.650 0.350 0.000
H40.8 Other glaucoma
0.649 0.351 0.000
E13 Other specified diabetes mellitus
0.649 0.351 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.648 0.352 0.000
K11.5 Sialolithiasis
0.648 0.352 0.000
E05.8 Other thyrotoxicosis
0.646 0.354 0.000
E05.5 Thyroid crisis or storm
0.646 0.354 0.000
E05.4 Thyrotoxicosis factitia
0.646 0.354 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.646 0.354 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.646 0.354 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.646 0.354 0.000
T98 Sequelae of other and unspecified effects of external causes
0.645 0.355 0.000
T95 Sequelae of burns, corrosions and frostbite
0.645 0.355 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.645 0.355 0.000
T91 Sequelae of injuries of neck and trunk
0.645 0.355 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.645 0.355 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.645 0.355 0.000
H02.0 Entropion and trichiasis of eyelid
0.645 0.355 0.000
E27.1 Primary adrenocortical insufficiency
0.645 0.355 0.000
E26.0 Primary hyperaldosteronism
0.645 0.355 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.645 0.355 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.645 0.355 0.000
K13.5 Oral submucous fibrosis
0.645 0.355 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.645 0.355 0.000
K13.3 Hairy leukoplakia
0.645 0.355 0.000
K13.1 Cheek and lip biting
0.645 0.355 0.000
L93 Lupus erythematosus
0.645 0.355 0.000
I88 Nonspecific lymphadenitis
0.644 0.355 0.000
Chapter XXII Codes for special purposes
0.644 0.356 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.644 0.356 0.000
K75.2 Nonspecific reactive hepatitis
0.644 0.356 0.000
K75.1 Phlebitis of portal vein
0.644 0.356 0.000
K74.0 Hepatic fibrosis
0.643 0.357 0.000
S06.5 Traumatic subdural haemorrhage
0.641 0.359 0.000
S59 Other and unspecified injuries of forearm
0.641 0.359 0.000
S58 Traumatic amputation of forearm
0.641 0.359 0.000
S57 Crushing injury of forearm
0.641 0.359 0.000
S56 Injury of muscle and tendon at forearm level
0.641 0.359 0.000
S55 Injury of blood vessels at forearm level
0.641 0.359 0.000
S54 Injury of nerves at forearm level
0.641 0.359 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.641 0.359 0.000
K40-K46 Hernia
0.640 0.360 0.000
T90.9 Sequelae of unspecified injury of head
0.638 0.362 0.000
K02.5 Caries with pulp exposure
0.638 0.362 0.000
K02.4 Odontoclasia
0.638 0.362 0.000
K02.3 Arrested dental caries
0.638 0.362 0.000
K02.2 Caries of cementum
0.638 0.362 0.000
K02.1 Caries of dentin
0.638 0.362 0.000
K02.0 Caries limited to enamel
0.638 0.362 0.000
Q25 Congenital malformations of great arteries
0.637 0.363 0.000
I80 Phlebitis and thrombophlebitis
0.637 0.363 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.637 0.363 0.000
L05 Pilonidal cyst
0.636 0.364 0.000
H17 Corneal scars and opacities
0.636 0.364 0.000
H35 Other retinal disorders
0.635 0.365 0.000
K74.6 Other and unspecified cirrhosis of liver
0.634 0.366 0.000
Y43.0 Antiallergic and antiemetic drugs
0.634 0.366 0.000
K05 Gingivitis and periodontal diseases
0.634 0.366 0.000
I82 Other venous embolism and thrombosis
0.633 0.367 0.000
S06.2 Diffuse brain injury
0.633 0.367 0.000
S00.9 Superficial injury of head, part unspecified
0.633 0.367 0.000
E27.9 Disorder of adrenal gland, unspecified
0.633 0.367 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.367 0.000
K65.9 Peritonitis, unspecified
0.632 0.367 0.000
H06.2 Dysthyroid exophthalmos
0.632 0.368 0.000
T18 Foreign body in alimentary tract
0.632 0.368 0.000
I07 Rheumatic tricuspid valve diseases
0.631 0.369 0.000
H42 Glaucoma in diseases classified elsewhere
0.631 0.369 0.000
K70 Alcoholic liver disease
0.631 0.369 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.630 0.369 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.630 0.369 0.000
L87 Transepidermal elimination disorders
0.630 0.369 0.000
L88 Pyoderma gangrenosum
0.630 0.369 0.000
L86 Keratoderma in diseases classified elsewhere
0.630 0.369 0.000
L83 Acanthosis nigricans
0.630 0.369 0.000
L80 Vitiligo
0.630 0.369 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.630 0.370 0.000
S52.7 Multiple fractures of forearm
0.630 0.370 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.630 0.370 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.630 0.370 0.000
I86 Varicose veins of other sites
0.630 0.370 0.000
I72.4 Aneurysm of artery of lower extremity
0.629 0.371 0.000
H81.9 Disorder of vestibular function, unspecified
0.629 0.371 0.000
H81.8 Other disorders of vestibular function
0.629 0.371 0.000
H81.4 Vertigo of central origin
0.629 0.371 0.000
H81.3 Other peripheral vertigo
0.629 0.371 0.000
H81.2 Vestibular neuronitis
0.629 0.371 0.000
L98.0 Pyogenic granuloma
0.629 0.371 0.000
Y45.2 Propionic acid derivatives
0.629 0.371 0.000
I12.0 Hypertensive renal disease with renal failure
0.629 0.371 0.000
Y57.5 X-ray contrast media
0.628 0.371 0.000
H60-H62 Diseases of external ear
0.628 0.372 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.628 0.372 0.000
K90-K93 Other diseases of the digestive system
0.628 0.372 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.627 0.373 0.000
V10-V19 Pedal cyclist injured in transport accident
0.627 0.373 0.000
I85.0 Oesophageal varices with bleeding
0.626 0.374 0.000
S52.10 Fracture of upper end of radius (closed)
0.626 0.374 0.000
S64 Injury of nerves at wrist and hand level
0.625 0.375 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.625 0.375 0.000
E04 Other non-toxic goitre
0.625 0.375 0.000
I72.8 Aneurysm of other specified arteries
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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