TreeWAS – Variant ID: rs188951355

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.446	0.554
Chapter V Mental and behavioural disorders	0.445	0.555
F40-F48 Neurotic, stress-related and somatoform disorders	0.442	0.558
Chapter IX Diseases of the circulatory system	0.440	0.560
F41 Other anxiety disorders	0.440	0.560
F41.9 Anxiety disorder, unspecified	0.428	0.572
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.425	0.575
I60-I69 Cerebrovascular diseases	0.410	0.590
Chapter X Diseases of the respiratory system	0.405	0.595
Chapter VI Diseases of the nervous system	0.405	0.595
Chapter II Neoplasms	0.400	0.600
F30-F39 Mood [affective] disorders	0.393	0.607
I70-I79 Diseases of arteries, arterioles and capillaries	0.393	0.607
I30-I52 Other forms of heart disease	0.386	0.614
I20-I25 Ischaemic heart diseases	0.383	0.617
Chapter IV Endocrine, nutritional and metabolic diseases	0.382	0.618
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.380	0.620
D10-D36 Benign neoplasms	0.379	0.621
F41.2 Mixed anxiety and depressive disorder	0.373	0.627
J09-J18 Influenza and pneumonia	0.367	0.633
G40-G47 Episodic and paroxysmal disorders	0.367	0.633
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.361	0.639
Chapter XV Pregnancy, childbirth and the puerperium	0.359	0.641
S80-S89 Injuries to the knee and lower leg	0.356	0.644
I67 Other cerebrovascular diseases	0.355	0.645
I20 Angina pectoris	0.353	0.647
Chapter VII Diseases of the eye and adnexa	0.347	0.653
S60-S69 Injuries to the wrist and hand	0.346	0.654
F40 Phobic anxiety disorders	0.342	0.658
I05-I09 Chronic rheumatic heart diseases	0.342	0.658
D24 Benign neoplasm of breast	0.342	0.658
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.342	0.658
I63 Cerebral infarction	0.340	0.659
J18 Pneumonia, organism unspecified	0.340	0.660
I73 Other peripheral vascular diseases	0.339	0.661
E70-E90 Metabolic disorders	0.338	0.662
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.336	0.664
T15-T19 Effects of foreign body entering through natural orifice	0.335	0.664
I95-I99 Other and unspecified disorders of the circulatory system	0.332	0.668
J95-J99 Other diseases of the respiratory system	0.330	0.670
J00-J06 Acute upper respiratory infections	0.329	0.671
I64 Stroke, not specified as haemorrhage or infarction	0.328	0.672
Chapter XI Diseases of the digestive system	0.328	0.672
I45 Other conduction disorders	0.327	0.673
S40-S49 Injuries to the shoulder and upper arm	0.327	0.673
I20.9 Angina pectoris, unspecified	0.326	0.674
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.325	0.675
F32 Depressive episode	0.324	0.676
T36-T50 Poisoning by drugs, medicaments and biological substances	0.324	0.676
Chapter VIII Diseases of the ear and mastoid process	0.323	0.677
G47 Sleep disorders	0.322	0.678
S20-S29 Injuries to the thorax	0.321	0.679
C15-C26 Malignant neoplasms of digestive organs	0.321	0.679
G80-G83 Cerebral palsy and other paralytic syndromes	0.321	0.679
Chapter XXII Codes for special purposes	0.320	0.680
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.320	0.680
Chapter XVI Certain conditions originating in the perinatal period	0.320	0.680
F99-F99 Unspecified mental disorder	0.319	0.681
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.319	0.681
F80-F89 Disorders of psychological development	0.319	0.681
F70-F79 Mental retardation	0.319	0.681
F60-F69 Disorders of adult personality and behaviour	0.319	0.681
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.319	0.681
F00-F09 Organic, including symptomatic, mental disorders	0.319	0.681
D27 Benign neoplasm of ovary	0.319	0.681
I35 Nonrheumatic aortic valve disorders	0.318	0.682
F48 Other neurotic disorders	0.317	0.683
F45 Somatoform disorders	0.317	0.683
F44 Dissociative [conversion] disorders	0.317	0.683
F43 Reaction to severe stress, and adjustment disorders	0.317	0.683
F42 Obsessive-compulsive disorder	0.317	0.683
D37-D48 Neoplasms of uncertain or unknown behaviour	0.316	0.684
T93 Sequelae of injuries of lower limb	0.316	0.684
I00-I02 Acute rheumatic fever	0.316	0.684
F41.8 Other specified anxiety disorders	0.316	0.684
F41.3 Other mixed anxiety disorders	0.316	0.684
F41.1 Generalised anxiety disorder	0.316	0.684
I21 Acute myocardial infarction	0.316	0.684
F31 Bipolar affective disorder	0.315	0.685
S50-S59 Injuries to the elbow and forearm	0.314	0.686
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.314	0.686
G20-G26 Extrapyramidal and movement disorders	0.313	0.687
I73.9 Peripheral vascular disease, unspecified	0.311	0.689
F33 Recurrent depressive disorder	0.310	0.690
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.310	0.690
I60 Subarachnoid haemorrhage	0.309	0.691
G90-G99 Other disorders of the nervous system	0.308	0.692
S82 Fracture of lower leg, including ankle	0.307	0.693
J30-J39 Other diseases of upper respiratory tract	0.306	0.694
I74 Arterial embolism and thrombosis	0.305	0.695
I44 Atrioventricular and left bundle-branch block	0.305	0.695
K58.9 Irritable bowel syndrome without diarrhoea	0.305	0.695
T79-T79 Certain early complications of trauma	0.305	0.695
T66-T78 Other and unspecified effects of external causes	0.305	0.695
T33-T35 Frostbite	0.305	0.695
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.305	0.695
T26-T28 Burns and corrosions confined to eye and internal organs	0.305	0.695
T20-T25 Burns and corrosions of external body surface, specified by site	0.305	0.695
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.305	0.695
T00-T07 Injuries involving multiple body regions	0.305	0.695
S90-S99 Injuries to the ankle and foot	0.305	0.695
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.305	0.695
S10-S19 Injuries to the neck	0.305	0.695
G45 Transient cerebral ischaemic attacks and related syndromes	0.304	0.696
K58 Irritable bowel syndrome	0.304	0.696
I70 Atherosclerosis	0.303	0.696
I69 Sequelae of cerebrovascular disease	0.301	0.698
K55-K64 Other diseases of intestines	0.301	0.699
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.300	0.700
E78.5 Hyperlipidaemia, unspecified	0.299	0.701
S70-S79 Injuries to the hip and thigh	0.298	0.702
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.298	0.702
J18.1 Lobar pneumonia, unspecified	0.298	0.702
I67.8 Other specified cerebrovascular diseases	0.298	0.702
J20-J22 Other acute lower respiratory infections	0.298	0.702
I47 Paroxysmal tachycardia	0.296	0.704
S66 Injury of muscle and tendon at wrist and hand level	0.295	0.704
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.295	0.705
J60-J70 Lung diseases due to external agents	0.295	0.705
J18.9 Pneumonia, unspecified	0.294	0.706
I68 Cerebrovascular disorders in diseases classified elsewhere	0.294	0.706
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.294	0.706
I62 Other nontraumatic intracranial haemorrhage	0.294	0.706
I61 Intracerebral haemorrhage	0.294	0.706
C64-C68 Malignant neoplasms of urinary tract	0.294	0.706
Chapter I Certain infectious and parasitic diseases	0.292	0.708
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.291	0.709
G70-G73 Diseases of myoneural junction and muscle	0.291	0.709
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.291	0.709
G30-G32 Other degenerative diseases of the nervous system	0.291	0.709
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.291	0.709
G00-G09 Inflammatory diseases of the central nervous system	0.291	0.709
I63.9 Cerebral infarction, unspecified	0.291	0.709
G47.3 Sleep apnoea	0.290	0.709
S00-S09 Injuries to the head	0.290	0.710
C50-C50 Malignant neoplasm of breast	0.290	0.710
D36 Benign neoplasm of other and unspecified sites	0.289	0.711
I51 Complications and ill-defined descriptions of heart disease	0.289	0.711
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.287	0.713
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.287	0.713
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.287	0.713
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.287	0.713
C40-C41 Malignant neoplasms of bone and articular cartilage	0.287	0.713
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.287	0.713
I31 Other diseases of pericardium	0.286	0.714
J80-J84 Other respiratory diseases principally affecting the interstitium	0.285	0.714
I45.1 Other and unspecified right bundle-branch block	0.285	0.715
I67.9 Cerebrovascular disease, unspecified	0.285	0.715
D12.3 Transverse colon	0.284	0.716
O80-O84 Delivery	0.283	0.717
F38 Other mood [affective] disorders	0.282	0.718
F34 Persistent mood [affective] disorders	0.282	0.718
F30 Manic episode	0.282	0.718
F39 Unspecified mood [affective] disorder	0.282	0.718
T51 Toxic effect of alcohol	0.282	0.718
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.282	0.718
I78 Diseases of capillaries	0.282	0.718
I72 Other aneurysm	0.282	0.718
I71 Aortic aneurysm and dissection	0.282	0.718
I77 Other disorders of arteries and arterioles	0.281	0.718
E65-E68 Obesity and other hyperalimentation	0.281	0.719
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.280	0.719
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.280	0.719
G40 Epilepsy	0.280	0.720
D22 Melanocytic naevi	0.279	0.721
E83 Disorders of mineral metabolism	0.279	0.721
G50-G59 Nerve, nerve root and plexus disorders	0.277	0.722
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.277	0.723
I52 Other heart disorders in diseases classified elsewhere	0.277	0.723
I48 Atrial fibrillation and flutter	0.277	0.723
I46 Cardiac arrest	0.277	0.723
I43 Cardiomyopathy in diseases classified elsewhere	0.277	0.723
I42 Cardiomyopathy	0.277	0.723
I41 Myocarditis in diseases classified elsewhere	0.277	0.723
I40 Acute myocarditis	0.277	0.723
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.277	0.723
I37 Pulmonary valve disorders	0.277	0.723
I36 Nonrheumatic tricuspid valve disorders	0.277	0.723
I33 Acute and subacute endocarditis	0.277	0.723
I32 Pericarditis in diseases classified elsewhere	0.277	0.723
I30 Acute pericarditis	0.277	0.723
I38 Endocarditis, valve unspecified	0.277	0.723
E10-E14 Diabetes mellitus	0.277	0.723
C51-C58 Malignant neoplasms of female genital organs	0.276	0.723
K13 Other diseases of lip and oral mucosa	0.276	0.724
D23 Other benign neoplasms of skin	0.276	0.724
J98 Other respiratory disorders	0.275	0.725
H30-H36 Disorders of choroid and retina	0.275	0.725
O94-O99 Other obstetric conditions, not elsewhere classified	0.275	0.725
I49 Other cardiac arrhythmias	0.275	0.725
H43-H45 Disorders of vitreous body and globe	0.274	0.725
I23 Certain current complications following acute myocardial infarction	0.274	0.726
I22 Subsequent myocardial infarction	0.274	0.726
F32.9 Depressive episode, unspecified	0.274	0.726
E50-E64 Other nutritional deficiencies	0.274	0.726
E40-E46 Malnutrition	0.274	0.726
E20-E35 Disorders of other endocrine glands	0.274	0.726
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.274	0.726
D25 Leiomyoma of uterus	0.274	0.726
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.273	0.727
O20-O29 Other maternal disorders predominantly related to pregnancy	0.273	0.727
D12.6 Colon, unspecified	0.272	0.728
D35 Benign neoplasm of other and unspecified endocrine glands	0.272	0.728
D33 Benign neoplasm of brain and other parts of central nervous system	0.272	0.728
D32 Benign neoplasm of meninges	0.272	0.728
D31 Benign neoplasm of eye and adnexa	0.272	0.728
D30 Benign neoplasm of urinary organs	0.272	0.728
D29 Benign neoplasm of male genital organs	0.272	0.728
D28 Benign neoplasm of other and unspecified female genital organs	0.272	0.728
D26 Other benign neoplasms of uterus	0.272	0.728
D21 Other benign neoplasms of connective and other soft tissue	0.272	0.728
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.272	0.728
D19 Benign neoplasm of mesothelial tissue	0.272	0.728
D16 Benign neoplasm of bone and articular cartilage	0.272	0.728
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.272	0.728
D14 Benign neoplasm of middle ear and respiratory system	0.272	0.728
D11 Benign neoplasm of major salivary glands	0.272	0.728
D10 Benign neoplasm of mouth and pharynx	0.272	0.728
D34 Benign neoplasm of thyroid gland	0.272	0.728
O00-O08 Pregnancy with abortive outcome	0.272	0.728
I08 Multiple valve diseases	0.272	0.728
J90-J94 Other diseases of pleura	0.271	0.729
T17 Foreign body in respiratory tract	0.271	0.729
F40.2 Specific (isolated) phobias	0.271	0.729
I35.0 Aortic (valve) stenosis	0.270	0.730
K08 Other disorders of teeth and supporting structures	0.269	0.730
I20.0 Unstable angina	0.269	0.731
I24 Other acute ischaemic heart diseases	0.269	0.731
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.267	0.733
D18 Haemangioma and lymphangioma, any site	0.267	0.733
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.267	0.733
D00-D09 In situ neoplasms	0.266	0.734
I21.1 Acute transmural myocardial infarction of inferior wall	0.264	0.736
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.264	0.736
C43-C44 Melanoma and other malignant neoplasms of skin	0.263	0.736
J17 Pneumonia in diseases classified elsewhere	0.263	0.737
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.263	0.737
J15 Bacterial pneumonia, not elsewhere classified	0.263	0.737
J12 Viral pneumonia, not elsewhere classified	0.263	0.737
J11 Influenza, virus not identified	0.263	0.737
J10 Influenza due to identified influenza virus	0.263	0.737
J14 Pneumonia due to Haemophilus influenzae	0.263	0.737
J13 Pneumonia due to Streptococcus pneumoniae	0.263	0.737
J09 Influenza due to certain identified influenza virus	0.263	0.737
G46 Vascular syndromes of brain in cerebrovascular diseases	0.263	0.737
G44 Other headache syndromes	0.263	0.737
G41 Status epilepticus	0.263	0.737
I20.8 Other forms of angina pectoris	0.262	0.738
I34 Nonrheumatic mitral valve disorders	0.261	0.739
S82.8 Fractures of other parts of lower leg	0.260	0.740
G81 Hemiplegia	0.260	0.740
G45.9 Transient cerebral ischaemic attack, unspecified	0.260	0.740
T98 Sequelae of other and unspecified effects of external causes	0.259	0.741
T95 Sequelae of burns, corrosions and frostbite	0.259	0.741
T94 Sequelae of injuries involving multiple and unspecified body regions	0.259	0.741
T92 Sequelae of injuries of upper limb	0.259	0.741
T91 Sequelae of injuries of neck and trunk	0.259	0.741
T90 Sequelae of injuries of head	0.259	0.741
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.259	0.741
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.259	0.741
F31.9 Bipolar affective disorder, unspecified	0.258	0.742
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.258	0.742
J00 Acute nasopharyngitis [common cold]	0.258	0.742
F20 Schizophrenia	0.257	0.742
O85-O92 Complications predominantly related to the puerperium	0.257	0.743
C18 Malignant neoplasm of colon	0.257	0.743
I44.0 Atrioventricular block, first degree	0.257	0.743
Chapter XX External causes of morbidity and mortality	0.256	0.744
S42 Fracture of shoulder and upper arm	0.256	0.744
T93.2 Sequelae of other fractures of lower limb	0.256	0.744
K58.0 Irritable bowel syndrome with diarrhoea	0.256	0.744
D45 Polycythaemia vera	0.256	0.744
S89 Other and unspecified injuries of lower leg	0.256	0.744
S88 Traumatic amputation of lower leg	0.256	0.744
S87 Crushing injury of lower leg	0.256	0.744
S86 Injury of muscle and tendon at lower leg level	0.256	0.744
S85 Injury of blood vessels at lower leg level	0.256	0.744
S84 Injury of nerves at lower leg level	0.256	0.744
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.256	0.744
S81 Open wound of lower leg	0.256	0.744
S80 Superficial injury of lower leg	0.256	0.744
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.255	0.745
H53-H54 Visual disturbances and blindness	0.255	0.745
I67.7 Cerebral arteritis, not elsewhere classified	0.255	0.745
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.255	0.745
I67.5 Moyamoya disease	0.255	0.745
I67.4 Hypertensive encephalopathy	0.255	0.745
I67.3 Progressive vascular leukoencephalopathy	0.255	0.745
I67.2 Cerebral atherosclerosis	0.255	0.745
I67.1 Cerebral aneurysm, nonruptured	0.255	0.745
I67.0 Dissection of cerebral arteries, nonruptured	0.255	0.745
I95 Hypotension	0.254	0.746
I20.1 Angina pectoris with documented spasm	0.254	0.746
H02 Other disorders of eyelid	0.253	0.747
H80-H83 Diseases of inner ear	0.252	0.748
G35-G37 Demyelinating diseases of the central nervous system	0.252	0.748
Chapter XII Diseases of the skin and subcutaneous tissue	0.252	0.748
E00-E07 Disorders of thyroid gland	0.251	0.749
F33.9 Recurrent depressive disorder, unspecified	0.250	0.749
H55-H59 Other disorders of eye and adnexa	0.249	0.751
H46-H48 Disorders of optic nerve and visual pathways	0.249	0.751
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.249	0.751
H10-H13 Disorders of conjunctiva	0.249	0.751
S69 Other and unspecified injuries of wrist and hand	0.248	0.752
S68 Traumatic amputation of wrist and hand	0.248	0.752
S67 Crushing injury of wrist and hand	0.248	0.752
S65 Injury of blood vessels at wrist and hand level	0.248	0.752
S64 Injury of nerves at wrist and hand level	0.248	0.752
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.248	0.752
S60 Superficial injury of wrist and hand	0.248	0.752
J06 Acute upper respiratory infections of multiple and unspecified sites	0.247	0.753
S62 Fracture at wrist and hand level	0.247	0.753
S22 Fracture of rib(s), sternum and thoracic spine	0.247	0.753
G20 Parkinson's disease	0.247	0.753
J02 Acute pharyngitis	0.247	0.753
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.246	0.754
F40.9 Phobic anxiety disorder, unspecified	0.245	0.754
F40.8 Other phobic anxiety disorders	0.245	0.754
F40.1 Social phobias	0.245	0.754
F40.0 Agoraphobia	0.245	0.754
I09 Other rheumatic heart diseases	0.245	0.755
I07 Rheumatic tricuspid valve diseases	0.245	0.755
I06 Rheumatic aortic valve diseases	0.245	0.755
I05 Rheumatic mitral valve diseases	0.245	0.755
T65 Toxic effect of other and unspecified substances	0.245	0.755
T63 Toxic effect of contact with venomous animals	0.245	0.755
T62 Toxic effect of other noxious substances eaten as food	0.245	0.755
T61 Toxic effect of noxious substances eaten as seafood	0.245	0.755
T60 Toxic effect of pesticides	0.245	0.755
T59 Toxic effect of other gases, fumes and vapours	0.245	0.755
T57 Toxic effect of other inorganic substances	0.245	0.755
T56 Toxic effect of metals	0.245	0.755
T54 Toxic effect of corrosive substances	0.245	0.755
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.245	0.755
T52 Toxic effect of organic solvents	0.245	0.755
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.245	0.755
T58 Toxic effect of carbon monoxide	0.245	0.755
T55 Toxic effect of soaps and detergents	0.245	0.755
D12.0 Caecum	0.245	0.755
I63.8 Other cerebral infarction	0.244	0.756
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.244	0.756
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.244	0.756
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.244	0.756
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.244	0.756
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.244	0.756
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.244	0.756
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.244	0.756
K13.0 Diseases of lips	0.244	0.756
J18.8 Other pneumonia, organism unspecified	0.244	0.756
J18.2 Hypostatic pneumonia, unspecified	0.244	0.756
J18.0 Bronchopneumonia, unspecified	0.244	0.756
I47.2 Ventricular tachycardia	0.244	0.756
C20 Malignant neoplasm of rectum	0.244	0.756
I73.8 Other specified peripheral vascular diseases	0.243	0.757
I73.1 Thromboangiitis obliterans [Buerger]	0.243	0.757
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.243	0.757
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.243	0.757
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.242	0.757
E88 Other metabolic disorders	0.242	0.757
E85 Amyloidosis	0.242	0.757
E84 Cystic fibrosis	0.242	0.757
E80 Disorders of porphyrin and bilirubin metabolism	0.242	0.757
E79 Disorders of purine and pyrimidine metabolism	0.242	0.757
E77 Disorders of glycoprotein metabolism	0.242	0.757
E76 Disorders of glycosaminoglycan metabolism	0.242	0.757
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.242	0.757
E74 Other disorders of carbohydrate metabolism	0.242	0.757
E73 Lactose intolerance	0.242	0.757
E72 Other disorders of amino-acid metabolism	0.242	0.757
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.242	0.757
E70 Disorders of aromatic amino-acid metabolism	0.242	0.757
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.242	0.757
S82.3 Fracture of lower end of tibia	0.242	0.758
J33 Nasal polyp	0.242	0.758
F25 Schizoaffective disorders	0.241	0.759
F23 Acute and transient psychotic disorders	0.241	0.759
F22 Persistent delusional disorders	0.241	0.759
F29 Unspecified nonorganic psychosis	0.241	0.759
F28 Other nonorganic psychotic disorders	0.241	0.759
F24 Induced delusional disorder	0.241	0.759
F21 Schizotypal disorder	0.241	0.759
T19 Foreign body in genito-urinary tract	0.241	0.759
T18 Foreign body in alimentary tract	0.241	0.759
T15 Foreign body on external eye	0.241	0.759
T16 Foreign body in ear	0.241	0.759
K08.3 Retained dental root	0.241	0.759
G91 Hydrocephalus	0.240	0.759
I70.2 Atherosclerosis of arteries of the extremities	0.240	0.760
T51.0 Ethanol	0.239	0.761
I98 Other disorders of circulatory system in diseases classified elsewhere	0.238	0.762
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.238	0.762
I99 Other and unspecified disorders of circulatory system	0.238	0.762
G43 Migraine	0.237	0.763
D12.5 Sigmoid colon	0.237	0.763
S61 Open wound of wrist and hand	0.237	0.763
J99 Respiratory disorders in diseases classified elsewhere	0.236	0.763
J96 Respiratory failure, not elsewhere classified	0.236	0.763
J95 Postprocedural respiratory disorders, not elsewhere classified	0.236	0.763
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.236	0.764
I60.9 Subarachnoid haemorrhage, unspecified	0.236	0.764
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.236	0.764
J04 Acute laryngitis and tracheitis	0.236	0.764
J03 Acute tonsillitis	0.236	0.764
J01 Acute sinusitis	0.236	0.764
S52 Fracture of forearm	0.235	0.765
I21.4 Acute subendocardial myocardial infarction	0.235	0.765
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.235	0.765
I45.9 Conduction disorder, unspecified	0.235	0.765
I45.8 Other specified conduction disorders	0.235	0.765
I45.6 Preexcitation syndrome	0.235	0.765
I45.5 Other specified heart block	0.235	0.765
I45.4 Nonspecific intraventricular block	0.235	0.765
I45.3 Trifascicular block	0.235	0.765
I45.2 Bifascicular block	0.235	0.765
I45.0 Right fascicular block	0.235	0.765
S49 Other and unspecified injuries of shoulder and upper arm	0.234	0.765
S48 Traumatic amputation of shoulder and upper arm	0.234	0.765
S46 Injury of muscle and tendon at shoulder and upper arm level	0.234	0.765
S45 Injury of blood vessels at shoulder and upper arm level	0.234	0.765
S44 Injury of nerves at shoulder and upper arm level	0.234	0.765
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.234	0.765
S41 Open wound of shoulder and upper arm	0.234	0.765
S40 Superficial injury of shoulder and upper arm	0.234	0.765
S47 Crushing injury of shoulder and upper arm	0.234	0.765
K70-K77 Diseases of liver	0.234	0.766
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.234	0.766
E83.1 Disorders of iron metabolism	0.234	0.766
D12.2 Ascending colon	0.234	0.766
D12.9 Anus and anal canal	0.233	0.767
D12.7 Rectosigmoid junction	0.233	0.767
D12.1 Appendix	0.233	0.767
H04 Disorders of lachrymal system	0.233	0.767
F32.8 Other depressive episodes	0.232	0.767
F32.3 Severe depressive episode with psychotic symptoms	0.232	0.767
F32.2 Severe depressive episode without psychotic symptoms	0.232	0.767
F32.1 Moderate depressive episode	0.232	0.767
F32.0 Mild depressive episode	0.232	0.767
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.232	0.768
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.232	0.768
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.232	0.768
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.232	0.768
T46 Poisoning by agents primarily affecting the cardiovascular system	0.232	0.768
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.232	0.768
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.232	0.768
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.232	0.768
T41 Poisoning by anaesthetics and therapeutic gases	0.232	0.768
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.232	0.768
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.232	0.768
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.232	0.768
T36 Poisoning by systemic antibiotics	0.232	0.768
H65-H75 Diseases of middle ear and mastoid	0.232	0.768
H60-H62 Diseases of external ear	0.232	0.768
I21.9 Acute myocardial infarction, unspecified	0.231	0.768
G93 Other disorders of brain	0.231	0.769
G47.8 Other sleep disorders	0.231	0.769
G47.4 Narcolepsy and cataplexy	0.231	0.769
G47.2 Disorders of the sleep-wake schedule	0.231	0.769
G47.1 Disorders of excessive somnolence [hypersomnias]	0.231	0.769
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.231	0.769
K04 Diseases of pulp and periapical tissues	0.231	0.769
G47.9 Sleep disorder, unspecified	0.231	0.769
S29 Other and unspecified injuries of thorax	0.230	0.769
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.230	0.769
S27 Injury of other and unspecified intrathoracic organs	0.230	0.769
S26 Injury of heart	0.230	0.769
S25 Injury of blood vessels of thorax	0.230	0.769
S24 Injury of nerves and spinal cord at thorax level	0.230	0.769
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.230	0.769
S21 Open wound of thorax	0.230	0.769
S20 Superficial injury of thorax	0.230	0.769
C26 Malignant neoplasm of other and ill-defined digestive organs	0.230	0.770
C25 Malignant neoplasm of pancreas	0.230	0.770
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.230	0.770
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.230	0.770
C21 Malignant neoplasm of anus and anal canal	0.230	0.770
C17 Malignant neoplasm of small intestine	0.230	0.770
C16 Malignant neoplasm of stomach	0.230	0.770
C15 Malignant neoplasm of oesophagus	0.230	0.770
C23 Malignant neoplasm of gallbladder	0.230	0.770
G83 Other paralytic syndromes	0.230	0.770
G82 Paraplegia and tetraplegia	0.230	0.770
G80 Infantile cerebral palsy	0.230	0.770
P90-P96 Other disorders originating in the perinatal period	0.230	0.770
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.230	0.770
P75-P78 Digestive system disorders of fetus and newborn	0.230	0.770
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.230	0.770
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.230	0.770
P35-P39 Infections specific to the perinatal period	0.230	0.770
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.230	0.770
P10-P15 Birth trauma	0.230	0.770
P05-P08 Disorders related to length of gestation and fetal growth	0.230	0.770
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.230	0.770
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.230	0.770
Q80-Q89 Other congenital malformations	0.230	0.770
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.230	0.770
Q60-Q64 Congenital malformations of the urinary system	0.230	0.770
Q50-Q56 Congenital malformations of genital organs	0.230	0.770
Q38-Q45 Other congenital malformations of the digestive system	0.230	0.770
Q35-Q37 Cleft lip and cleft palate	0.230	0.770
Q30-Q34 Congenital malformations of the respiratory system	0.230	0.770

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations