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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs189578969
log Bayes Factor = 2.27923
Chromosome 4   position 46,732,290  (GRCh37) Explore rs189578969 on Ensembl!
Variant rs189578969 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
Chapter II Neoplasms
0.966 0.034 0.000
Chapter XXI Factors influencing health status and contact with health services
0.964 0.036 0.000
D10-D36 Benign neoplasms
0.904 0.096 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.899 0.101 0.000
Chapter XIV Diseases of the genitourinary system
0.895 0.105 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.894 0.106 0.000
R50-R69 General symptoms and signs
0.892 0.108 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.876 0.124 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.852 0.148 0.000
Chapter V Mental and behavioural disorders
0.841 0.159 0.000
Chapter X Diseases of the respiratory system
0.841 0.159 0.000
Chapter IX Diseases of the circulatory system
0.827 0.173 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.826 0.174 0.000
R07 Pain in throat and chest
0.824 0.176 0.000
Chapter VII Diseases of the eye and adnexa
0.823 0.177 0.000
D25 Leiomyoma of uterus
0.812 0.188 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.810 0.190 0.000
R55 Syncope and collapse
0.808 0.192 0.000
C15-C26 Malignant neoplasms of digestive organs
0.777 0.223 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.773 0.227 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.772 0.228 0.000
M20-M25 Other joint disorders
0.771 0.229 0.000
Chapter I Certain infectious and parasitic diseases
0.768 0.232 0.000
Chapter VIII Diseases of the ear and mastoid process
0.766 0.234 0.000
Chapter XI Diseases of the digestive system
0.764 0.236 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.762 0.238 0.000
C60-C63 Malignant neoplasms of male genital organs
0.761 0.239 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.761 0.239 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.757 0.243 0.000
Z04 Examination and observation for other reasons
0.750 0.250 0.000
D25.9 Leiomyoma of uterus, unspecified
0.746 0.254 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.745 0.255 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.744 0.256 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.744 0.256 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.743 0.257 0.000
R07.4 Chest pain, unspecified
0.740 0.260 0.000
D36 Benign neoplasm of other and unspecified sites
0.737 0.263 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.733 0.267 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.732 0.268 0.000
N84 Polyp of female genital tract
0.726 0.274 0.000
N17-N19 Renal failure
0.725 0.274 0.000
I30-I52 Other forms of heart disease
0.715 0.285 0.000
J40-J47 Chronic lower respiratory diseases
0.714 0.286 0.000
R63 Symptoms and signs concerning food and fluid intake
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
M50-M54 Other dorsopathies
0.709 0.291 0.000
D27 Benign neoplasm of ovary
0.708 0.291 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.708 0.292 0.000
G40-G47 Episodic and paroxysmal disorders
0.708 0.292 0.000
Z45 Adjustment and management of implanted device
0.703 0.297 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.702 0.297 0.000
R30-R39 Symptoms and signs involving the urinary system
0.702 0.298 0.000
C50-C50 Malignant neoplasm of breast
0.701 0.299 0.000
R51 Headache
0.700 0.300 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.301 0.000
R47-R49 Symptoms and signs involving speech and voice
0.699 0.301 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.699 0.301 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.699 0.301 0.000
M20 Acquired deformities of fingers and toes
0.698 0.302 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.697 0.303 0.000
R60 Oedema, not elsewhere classified
0.693 0.307 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.692 0.308 0.000
D00-D09 In situ neoplasms
0.692 0.308 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.692 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.692 0.308 0.000
C64-C68 Malignant neoplasms of urinary tract
0.692 0.308 0.000
C51-C58 Malignant neoplasms of female genital organs
0.692 0.308 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.692 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.692 0.308 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.692 0.308 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.691 0.309 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.691 0.309 0.000
R04 Haemorrhage from respiratory passages
0.690 0.309 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.690 0.310 0.000
N92 Excessive, frequent and irregular menstruation
0.686 0.314 0.000
F30-F39 Mood [affective] disorders
0.685 0.315 0.000
R07.3 Other chest pain
0.684 0.316 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.683 0.317 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.683 0.317 0.000
M45-M49 Spondylopathies
0.680 0.320 0.000
Chapter XX External causes of morbidity and mortality
0.678 0.321 0.000
Z13 Special screening examination for other diseases and disorders
0.673 0.327 0.000
R59 Enlarged lymph nodes
0.672 0.328 0.000
I20-I25 Ischaemic heart diseases
0.671 0.329 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.667 0.333 0.000
H30-H36 Disorders of choroid and retina
0.666 0.334 0.000
Z03.8 Observation for other suspected diseases and conditions
0.666 0.334 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.661 0.339 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.659 0.341 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.658 0.342 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.658 0.342 0.000
J09-J18 Influenza and pneumonia
0.657 0.342 0.000
K55-K64 Other diseases of intestines
0.656 0.344 0.000
R00 Abnormalities of heart beat
0.655 0.344 0.000
R53 Malaise and fatigue
0.655 0.345 0.000
R06 Abnormalities of breathing
0.653 0.347 0.000
N84.0 Polyp of corpus uteri
0.653 0.347 0.000
M05-M14 Inflammatory polyarthropathies
0.649 0.351 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.648 0.352 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.648 0.352 0.000
D32 Benign neoplasm of meninges
0.648 0.352 0.000
D31 Benign neoplasm of eye and adnexa
0.648 0.352 0.000
D30 Benign neoplasm of urinary organs
0.648 0.352 0.000
D29 Benign neoplasm of male genital organs
0.648 0.352 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.648 0.352 0.000
D26 Other benign neoplasms of uterus
0.648 0.352 0.000
D23 Other benign neoplasms of skin
0.648 0.352 0.000
D22 Melanocytic naevi
0.648 0.352 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.648 0.352 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.648 0.352 0.000
D19 Benign neoplasm of mesothelial tissue
0.648 0.352 0.000
D18 Haemangioma and lymphangioma, any site
0.648 0.352 0.000
D17 Benign lipomatous neoplasm
0.648 0.352 0.000
D16 Benign neoplasm of bone and articular cartilage
0.648 0.352 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.648 0.352 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.648 0.352 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.648 0.352 0.000
D11 Benign neoplasm of major salivary glands
0.648 0.352 0.000
D10 Benign neoplasm of mouth and pharynx
0.648 0.352 0.000
D34 Benign neoplasm of thyroid gland
0.648 0.352 0.000
D24 Benign neoplasm of breast
0.648 0.352 0.000
Z43 Attention to artificial openings
0.646 0.354 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.644 0.356 0.000
Z10 Routine general health check-up of defined subpopulation
0.644 0.356 0.000
Z02 Examination and encounter for administrative purposes
0.644 0.356 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.644 0.356 0.000
Z04.3 Examination and observation following other accident
0.644 0.356 0.000
C20 Malignant neoplasm of rectum
0.643 0.357 0.000
L60-L75 Disorders of skin appendages
0.642 0.358 0.000
N99-N99 Other disorders of the genitourinary system
0.641 0.358 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.641 0.358 0.000
N60-N64 Disorders of breast
0.641 0.358 0.000
N25-N29 Other disorders of kidney and ureter
0.641 0.358 0.000
N20-N23 Urolithiasis
0.641 0.358 0.000
N10-N16 Renal tubulo-interstitial diseases
0.641 0.358 0.000
N00-N08 Glomerular diseases
0.641 0.358 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.641 0.359 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.641 0.359 0.000
R01 Cardiac murmurs and other cardiac sounds
0.641 0.359 0.000
R02 Gangrene, not elsewhere classified
0.641 0.359 0.000
R68 Other general symptoms and signs
0.640 0.360 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.640 0.360 0.000
R62 Lack of expected normal physiological development
0.640 0.360 0.000
R61 Hyperhidrosis
0.640 0.360 0.000
R57 Shock, not elsewhere classified
0.640 0.360 0.000
R56 Convulsions, not elsewhere classified
0.640 0.360 0.000
R52 Pain, not elsewhere classified
0.640 0.360 0.000
R64 Cachexia
0.640 0.360 0.000
R58 Haemorrhage, not elsewhere classified
0.640 0.360 0.000
R54 Senility
0.640 0.360 0.000
Z72 Problems related to lifestyle
0.635 0.365 0.000
N93 Other abnormal uterine and vaginal bleeding
0.633 0.367 0.000
M70-M79 Other soft tissue disorders
0.631 0.368 0.000
G56 Mononeuropathies of upper limb
0.630 0.370 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.628 0.372 0.000
M91-M94 Chondropathies
0.628 0.372 0.000
M86-M90 Other osteopathies
0.628 0.372 0.000
M65-M68 Disorders of synovium and tendon
0.628 0.372 0.000
M60-M63 Disorders of muscles
0.628 0.372 0.000
M40-M43 Deforming dorsopathies
0.628 0.372 0.000
M00-M03 Infectious arthropathies
0.628 0.372 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.624 0.375 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.624 0.376 0.000
G90-G99 Other disorders of the nervous system
0.623 0.376 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.623 0.376 0.000
G70-G73 Diseases of myoneural junction and muscle
0.623 0.376 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.623 0.376 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.623 0.376 0.000
G30-G32 Other degenerative diseases of the nervous system
0.623 0.376 0.000
G20-G26 Extrapyramidal and movement disorders
0.623 0.376 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.623 0.376 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.623 0.376 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.623 0.377 0.000
N95 Menopausal and other perimenopausal disorders
0.623 0.377 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.622 0.377 0.000
H25-H28 Disorders of lens
0.621 0.379 0.000
R50 Fever of unknown origin
0.620 0.380 0.000
M80-M85 Disorders of bone density and structure
0.617 0.382 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.617 0.383 0.000
Z12 Special screening examination for neoplasms
0.617 0.383 0.000
J30-J39 Other diseases of upper respiratory tract
0.615 0.385 0.000
C61 Malignant neoplasm of prostate
0.614 0.386 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.612 0.388 0.000
R94 Abnormal results of function studies
0.611 0.389 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.611 0.389 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.611 0.389 0.000
F99-F99 Unspecified mental disorder
0.603 0.397 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.603 0.397 0.000
F80-F89 Disorders of psychological development
0.603 0.397 0.000
F70-F79 Mental retardation
0.603 0.397 0.000
F60-F69 Disorders of adult personality and behaviour
0.603 0.397 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.603 0.397 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.603 0.397 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.603 0.397 0.000
R05 Cough
0.603 0.397 0.000
J95-J99 Other diseases of the respiratory system
0.603 0.397 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.603 0.397 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.603 0.397 0.000
J60-J70 Lung diseases due to external agents
0.603 0.397 0.000
J00-J06 Acute upper respiratory infections
0.603 0.397 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.602 0.398 0.000
H65-H75 Diseases of middle ear and mastoid
0.602 0.398 0.000
N18 Chronic renal failure
0.601 0.399 0.000
S00-S09 Injuries to the head
0.599 0.400 0.000
J90-J94 Other diseases of pleura
0.599 0.401 0.000
M20.1 Hallux valgus (acquired)
0.599 0.401 0.000
O00-O08 Pregnancy with abortive outcome
0.599 0.401 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.597 0.403 0.000
A00-A09 Intestinal infectious diseases
0.596 0.404 0.000
M20.4 Other hammer toe(s) (acquired)
0.593 0.407 0.000
I60-I69 Cerebrovascular diseases
0.593 0.407 0.000
I05-I09 Chronic rheumatic heart diseases
0.593 0.407 0.000
I00-I02 Acute rheumatic fever
0.593 0.407 0.000
N98 Complications associated with artificial fertilisation
0.592 0.408 0.000
N97 Female infertility
0.592 0.408 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.592 0.408 0.000
N91 Absent, scanty and rare menstruation
0.592 0.408 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.592 0.408 0.000
N89 Other noninflammatory disorders of vagina
0.592 0.408 0.000
N88 Other noninflammatory disorders of cervix uteri
0.592 0.408 0.000
N87 Dysplasia of cervix uteri
0.592 0.408 0.000
N82 Fistulae involving female genital tract
0.592 0.408 0.000
N80 Endometriosis
0.592 0.408 0.000
N96 Habitual aborter
0.592 0.408 0.000
N86 Erosion and ectropion of cervix uteri
0.592 0.408 0.000
R07.2 Precordial pain
0.591 0.409 0.000
R07.1 Chest pain on breathing
0.591 0.409 0.000
R07.0 Pain in throat
0.591 0.409 0.000
Z37 Outcome of delivery
0.590 0.410 0.000
H55-H59 Other disorders of eye and adnexa
0.590 0.410 0.000
H53-H54 Visual disturbances and blindness
0.590 0.410 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.590 0.410 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.590 0.410 0.000
H43-H45 Disorders of vitreous body and globe
0.590 0.410 0.000
H40-H42 Glaucoma
0.590 0.410 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.590 0.410 0.000
H10-H13 Disorders of conjunctiva
0.590 0.410 0.000
Z51 Other medical care
0.589 0.411 0.000
I25 Chronic ischaemic heart disease
0.589 0.411 0.000
K35-K38 Diseases of appendix
0.588 0.412 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.588 0.412 0.000
N30-N39 Other diseases of urinary system
0.588 0.412 0.000
R63.4 Abnormal weight loss
0.586 0.414 0.000
K70-K77 Diseases of liver
0.584 0.416 0.000
D25.2 Subserosal leiomyoma of uterus
0.582 0.418 0.000
D25.1 Intramural leiomyoma of uterus
0.582 0.418 0.000
D25.0 Submucous leiomyoma of uterus
0.582 0.418 0.000
Z54 Convalescence
0.581 0.419 0.000
Z52 Donors of organs and tissues
0.581 0.419 0.000
Z49 Care involving dialysis
0.581 0.419 0.000
Z48 Other surgical follow-up care
0.581 0.419 0.000
Z47 Other orthopaedic follow-up care
0.581 0.419 0.000
Z44 Fitting and adjustment of external prosthetic device
0.581 0.419 0.000
Z42 Follow-up care involving plastic surgery
0.581 0.419 0.000
Z41 Procedures for purposes other than remedying health state
0.581 0.419 0.000
Z40 Prophylactic surgery
0.581 0.419 0.000
Z50 Care involving use of rehabilitation procedures
0.580 0.420 0.000
R87 Abnormal findings in specimens from female genital organs
0.578 0.421 0.000
I51 Complications and ill-defined descriptions of heart disease
0.577 0.423 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.576 0.423 0.000
G40 Epilepsy
0.576 0.424 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.576 0.424 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.575 0.425 0.000
N81 Female genital prolapse
0.574 0.426 0.000
F32 Depressive episode
0.572 0.428 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.572 0.428 0.000
J47 Bronchiectasis
0.572 0.428 0.000
I71 Aortic aneurysm and dissection
0.570 0.430 0.000
Z45.8 Adjustment and management of other implanted devices
0.570 0.430 0.000
N40-N51 Diseases of male genital organs
0.570 0.430 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.569 0.431 0.000
I34 Nonrheumatic mitral valve disorders
0.568 0.432 0.000
K90-K93 Other diseases of the digestive system
0.564 0.436 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.563 0.437 0.000
C79 Secondary malignant neoplasm of other sites
0.562 0.438 0.000
M51 Other intervertebral disk disorders
0.562 0.438 0.000
B95-B98 Bacterial, viral and other infectious agents
0.561 0.439 0.000
J20-J22 Other acute lower respiratory infections
0.560 0.440 0.000
J44 Other chronic obstructive pulmonary disease
0.560 0.440 0.000
M25 Other joint disorders, not elsewhere classified
0.559 0.440 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.557 0.442 0.000
C25 Malignant neoplasm of pancreas
0.557 0.442 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.557 0.442 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.557 0.442 0.000
C21 Malignant neoplasm of anus and anal canal
0.557 0.442 0.000
C18 Malignant neoplasm of colon
0.557 0.442 0.000
C17 Malignant neoplasm of small intestine
0.557 0.442 0.000
C16 Malignant neoplasm of stomach
0.557 0.442 0.000
C15 Malignant neoplasm of oesophagus
0.557 0.442 0.000
C23 Malignant neoplasm of gallbladder
0.557 0.442 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.557 0.442 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.556 0.444 0.000
I50 Heart failure
0.556 0.444 0.000
G56.0 Carpal tunnel syndrome
0.556 0.444 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.555 0.444 0.000
D60-D64 Aplastic and other anaemias
0.554 0.446 0.000
C80 Malignant neoplasm without specification of site
0.554 0.446 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.554 0.446 0.000
Z76 Persons encountering health services in other circumstances
0.554 0.446 0.000
Z75 Problems related to medical facilities and other health care
0.554 0.446 0.000
Z74 Problems related to care-provider dependency
0.554 0.446 0.000
Z73 Problems related to life-management difficulty
0.554 0.446 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.554 0.446 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.554 0.446 0.000
I77 Other disorders of arteries and arterioles
0.554 0.446 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.553 0.447 0.000
M35 Other systemic involvement of connective tissue
0.553 0.447 0.000
M34 Systemic sclerosis
0.553 0.447 0.000
M33 Dermatopolymyositis
0.553 0.447 0.000
M32 Systemic lupus erythematosus
0.553 0.447 0.000
M31 Other necrotising vasculopathies
0.553 0.447 0.000
M30 Polyarteritis nodosa and related conditions
0.553 0.447 0.000
M24 Other specific joint derangements
0.553 0.447 0.000
M22 Disorders of patella
0.553 0.447 0.000
M21 Other acquired deformities of limbs
0.553 0.447 0.000
B99-B99 Other infectious diseases
0.550 0.449 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.550 0.449 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.550 0.449 0.000
B65-B83 Helminthiases
0.550 0.449 0.000
B50-B64 Protozoal diseases
0.550 0.449 0.000
B35-B49 Mycoses
0.550 0.449 0.000
B25-B34 Other viral diseases
0.550 0.449 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.550 0.449 0.000
B15-B19 Viral hepatitis
0.550 0.449 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.550 0.449 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.550 0.449 0.000
A80-A89 Viral infections of the central nervous system
0.550 0.449 0.000
A75-A79 Rickettsioses
0.550 0.449 0.000
A70-A74 Other diseases caused by chlamydiae
0.550 0.449 0.000
A65-A69 Other spirochaetal diseases
0.550 0.449 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.550 0.449 0.000
A30-A49 Other bacterial diseases
0.550 0.449 0.000
A20-A28 Certain zoonotic bacterial diseases
0.550 0.449 0.000
A15-A19 Tuberculosis
0.550 0.449 0.000
R60.0 Localised oedema
0.550 0.450 0.000
H90-H95 Other disorders of ear
0.549 0.451 0.000
H80-H83 Diseases of inner ear
0.549 0.451 0.000
H60-H62 Diseases of external ear
0.549 0.451 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.548 0.452 0.000
K65-K67 Diseases of peritoneum
0.548 0.452 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.548 0.452 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.546 0.454 0.000
L50-L54 Urticaria and erythema
0.546 0.454 0.000
L40-L45 Papulosquamous disorders
0.546 0.454 0.000
L20-L30 Dermatitis and eczema
0.546 0.454 0.000
L10-L14 Bullous disorders
0.546 0.454 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.546 0.454 0.000
C62 Malignant neoplasm of testis
0.546 0.454 0.000
C60 Malignant neoplasm of penis
0.546 0.454 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.546 0.454 0.000
O85-O92 Complications predominantly related to the puerperium
0.546 0.454 0.000
O80-O84 Delivery
0.546 0.454 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.546 0.454 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.546 0.454 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.546 0.454 0.000
R31 Unspecified haematuria
0.545 0.455 0.000
R04.2 Haemoptysis
0.545 0.455 0.000
M54 Dorsalgia
0.544 0.455 0.000
J45 Asthma
0.544 0.456 0.000
K50-K52 Noninfective enteritis and colitis
0.544 0.456 0.000
D50-D53 Nutritional anaemias
0.544 0.456 0.000
R39 Other symptoms and signs involving the urinary system
0.543 0.456 0.000
Z46 Fitting and adjustment of other devices
0.543 0.457 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.543 0.457 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.543 0.457 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.543 0.457 0.000
Z03.3 Observation for suspected nervous system disorder
0.543 0.457 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.543 0.457 0.000
Z03.1 Observation for suspected malignant neoplasm
0.543 0.457 0.000
Z03.0 Observation for suspected tuberculosis
0.543 0.457 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.543 0.457 0.000
K62 Other diseases of anus and rectum
0.541 0.459 0.000
Z01.8 Other specified special examinations
0.541 0.459 0.000
Z72.0 Tobacco use
0.540 0.460 0.000
M47 Spondylosis
0.539 0.461 0.000
O60-O75 Complications of labour and delivery
0.539 0.461 0.000
M23 Internal derangement of knee
0.538 0.462 0.000
Z04.9 Examination and observation for unspecified reason
0.538 0.462 0.000
Z04.8 Examination and observation for other specified reasons
0.538 0.462 0.000
Z04.6 General psychiatric examination, requested by authority
0.538 0.462 0.000
Z04.5 Examination and observation following other inflicted injury
0.538 0.462 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.538 0.462 0.000
Z04.2 Examination and observation following work accident
0.538 0.462 0.000
Z04.1 Examination and observation following transport accident
0.538 0.462 0.000
Z04.0 Blood-alcohol and blood-drug test
0.538 0.462 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.537 0.463 0.000
Z39 Postpartum care and examination
0.534 0.465 0.000
Z38 Liveborn infants according to place of birth
0.534 0.465 0.000
Z36 Antenatal screening
0.534 0.465 0.000
Z35 Supervision of high-risk pregnancy
0.534 0.465 0.000
Z34 Supervision of normal pregnancy
0.534 0.465 0.000
Z32 Pregnancy examination and test
0.534 0.465 0.000
Z31 Procreative management
0.534 0.465 0.000
Z33 Pregnant state, incidental
0.534 0.465 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.533 0.466 0.000
R86 Abnormal findings in specimens from male genital organs
0.533 0.466 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.533 0.466 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.533 0.466 0.000
R83 Abnormal findings in cerebrospinal fluid
0.533 0.466 0.000
D80-D89 Certain disorders involving the immune mechanism
0.533 0.467 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.533 0.467 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.533 0.467 0.000
D55-D59 Haemolytic anaemias
0.533 0.467 0.000
Z30 Contraceptive management
0.533 0.467 0.000
D36.9 Benign neoplasm of unspecified site
0.528 0.471 0.000
D36.7 Other specified sites
0.528 0.471 0.000
D36.0 Lymph nodes
0.528 0.471 0.000
H36 Retinal disorders in diseases classified elsewhere
0.528 0.472 0.000
Z43.2 Attention to ileostomy
0.528 0.472 0.000
J18 Pneumonia, organism unspecified
0.526 0.474 0.000
K58 Irritable bowel syndrome
0.526 0.474 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.526 0.474 0.000
G58 Other mononeuropathies
0.526 0.474 0.000
G57 Mononeuropathies of lower limb
0.526 0.474 0.000
G54 Nerve root and plexus disorders
0.526 0.474 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.526 0.474 0.000
G52 Disorders of other cranial nerves
0.526 0.474 0.000
G51 Facial nerve disorders
0.526 0.474 0.000
G50 Disorders of trigeminal nerve
0.526 0.474 0.000
N17 Acute renal failure
0.525 0.474 0.000
N84.1 Polyp of cervix uteri
0.525 0.475 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.525 0.475 0.000
T79-T79 Certain early complications of trauma
0.525 0.475 0.000
T66-T78 Other and unspecified effects of external causes
0.525 0.475 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.525 0.475 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.525 0.475 0.000
T33-T35 Frostbite
0.525 0.475 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.525 0.475 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.525 0.475 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.525 0.475 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.525 0.475 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.525 0.475 0.000
T00-T07 Injuries involving multiple body regions
0.525 0.475 0.000
S90-S99 Injuries to the ankle and foot
0.525 0.475 0.000
S80-S89 Injuries to the knee and lower leg
0.525 0.475 0.000
S70-S79 Injuries to the hip and thigh
0.525 0.475 0.000
S60-S69 Injuries to the wrist and hand
0.525 0.475 0.000
S40-S49 Injuries to the shoulder and upper arm
0.525 0.475 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.525 0.475 0.000
S20-S29 Injuries to the thorax
0.525 0.475 0.000
S10-S19 Injuries to the neck
0.525 0.475 0.000
R00.1 Bradycardia, unspecified
0.523 0.477 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.521 0.479 0.000
N84.9 Polyp of female genital tract, unspecified
0.521 0.479 0.000
N84.8 Polyp of other parts of female genital tract
0.521 0.479 0.000
N84.3 Polyp of vulva
0.521 0.479 0.000
N84.2 Polyp of vagina
0.521 0.479 0.000
N19 Unspecified renal failure
0.520 0.480 0.000
Z03.4 Observation for suspected myocardial infarction
0.520 0.480 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.519 0.480 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.517 0.483 0.000
S50-S59 Injuries to the elbow and forearm
0.516 0.484 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.516 0.484 0.000
C78.0 Secondary malignant neoplasm of lung
0.516 0.484 0.000
C44 Other malignant neoplasms of skin
0.514 0.486 0.000
R59.0 Localised enlarged lymph nodes
0.514 0.486 0.000
I52 Other heart disorders in diseases classified elsewhere
0.513 0.487 0.000
I49 Other cardiac arrhythmias
0.513 0.487 0.000
I48 Atrial fibrillation and flutter
0.513 0.487 0.000
I47 Paroxysmal tachycardia
0.513 0.487 0.000
I46 Cardiac arrest
0.513 0.487 0.000
I45 Other conduction disorders
0.513 0.487 0.000
I44 Atrioventricular and left bundle-branch block
0.513 0.487 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.513 0.487 0.000
I42 Cardiomyopathy
0.513 0.487 0.000
I41 Myocarditis in diseases classified elsewhere
0.513 0.487 0.000
I40 Acute myocarditis
0.513 0.487 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I37 Pulmonary valve disorders
0.513 0.487 0.000
I36 Nonrheumatic tricuspid valve disorders
0.513 0.487 0.000
I35 Nonrheumatic aortic valve disorders
0.513 0.487 0.000
I33 Acute and subacute endocarditis
0.513 0.487 0.000
I32 Pericarditis in diseases classified elsewhere
0.513 0.487 0.000
I31 Other diseases of pericardium
0.513 0.487 0.000
I30 Acute pericarditis
0.513 0.487 0.000
I38 Endocarditis, valve unspecified
0.513 0.487 0.000
Z92 Personal history of medical treatment
0.512 0.487 0.000
H35 Other retinal disorders
0.512 0.487 0.000
J43 Emphysema
0.512 0.488 0.000
J41 Simple and mucopurulent chronic bronchitis
0.512 0.488 0.000
J46 Status asthmaticus
0.512 0.488 0.000
J42 Unspecified chronic bronchitis
0.512 0.488 0.000
J40 Bronchitis, not specified as acute or chronic
0.512 0.488 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.512 0.488 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.512 0.488 0.000
R63.5 Abnormal weight gain
0.512 0.488 0.000
R63.3 Feeding difficulties and mismanagement
0.512 0.488 0.000
R63.2 Polyphagia
0.512 0.488 0.000
R63.1 Polydipsia
0.512 0.488 0.000
R63.0 Anorexia
0.512 0.488 0.000
C50 Malignant neoplasm of breast
0.511 0.488 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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