TreeWAS – Variant ID: rs191780267

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.992	0.008
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.985	0.015
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.976	0.024
Chapter VI Diseases of the nervous system	0.975	0.025
S80-S89 Injuries to the knee and lower leg	0.967	0.033
Chapter I Certain infectious and parasitic diseases	0.966	0.034
T36-T50 Poisoning by drugs, medicaments and biological substances	0.959	0.041
S00-S09 Injuries to the head	0.935	0.065
A00-A09 Intestinal infectious diseases	0.930	0.070
M05-M14 Inflammatory polyarthropathies	0.926	0.074
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.924	0.076
S82 Fracture of lower leg, including ankle	0.920	0.080
O36 Maternal care for other known or suspected foetal problems	0.919	0.081
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.919	0.081
H30-H36 Disorders of choroid and retina	0.914	0.086
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.909	0.091
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.903	0.097
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.897	0.103
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.894	0.106
O34 Maternal care for known or suspected abnormality of pelvic organs	0.894	0.106
H33 Retinal detachments and breaks	0.893	0.107
O94-O99 Other obstetric conditions, not elsewhere classified	0.885	0.115
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.880	0.120
A09.9 Gastroenteritis and colitis of unspecified origin	0.874	0.126
M13 Other arthritis	0.871	0.129
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.867	0.133
T39.1 4-Aminophenol derivatives	0.862	0.138
O60-O75 Complications of labour and delivery	0.857	0.143
M20-M25 Other joint disorders	0.853	0.147
S00 Superficial injury of head	0.851	0.149
O20-O29 Other maternal disorders predominantly related to pregnancy	0.849	0.151
H33.0 Retinal detachment with retinal break	0.846	0.154
M45-M49 Spondylopathies	0.843	0.157
M25 Other joint disorders, not elsewhere classified	0.841	0.159
H52 Disorders of refraction and accommodation	0.840	0.160
G62 Other polyneuropathies	0.836	0.164
H55-H59 Other disorders of eye and adnexa	0.836	0.164
O36.8 Maternal care for other specified foetal problems	0.833	0.167
M13.9 Arthritis, unspecified	0.832	0.168
Chapter XX External causes of morbidity and mortality	0.828	0.172
M65-M68 Disorders of synovium and tendon	0.827	0.173
M86-M90 Other osteopathies	0.825	0.175
S82.8 Fractures of other parts of lower leg	0.825	0.175
M25.7 Osteophyte	0.821	0.179
H53-H54 Visual disturbances and blindness	0.819	0.181
O32 Maternal care for known or suspected malpresentation of foetus	0.816	0.184
T81 Complications of procedures, not elsewhere classified	0.812	0.188
S82.1 Fracture of upper end of tibia	0.811	0.189
T85 Complications of other internal prosthetic devices, implants and grafts	0.809	0.191
O00-O08 Pregnancy with abortive outcome	0.809	0.191
O34.2 Maternal care due to uterine scar from previous surgery	0.805	0.195
B07 Viral warts	0.803	0.197
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.803	0.197
T66-T78 Other and unspecified effects of external causes	0.802	0.198
M25.77 Osteophyte (Ankle and foot)	0.801	0.199
Chapter V Mental and behavioural disorders	0.798	0.202
S90-S99 Injuries to the ankle and foot	0.793	0.207
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.793	0.207
H40-H42 Glaucoma	0.792	0.207
G40-G47 Episodic and paroxysmal disorders	0.791	0.209
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.790	0.210
S80 Superficial injury of lower leg	0.787	0.213
G50-G59 Nerve, nerve root and plexus disorders	0.785	0.215
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.783	0.217
T15-T19 Effects of foreign body entering through natural orifice	0.781	0.219
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.778	0.222
M80-M85 Disorders of bone density and structure	0.778	0.222
S82.3 Fracture of lower end of tibia	0.777	0.223
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.775	0.225
M07 Psoriatic and enteropathic arthropathies	0.774	0.226
S10-S19 Injuries to the neck	0.773	0.227
H33.2 Serous retinal detachment	0.773	0.227
A08 Viral and other specified intestinal infections	0.773	0.227
S20-S29 Injuries to the thorax	0.769	0.231
O42 Premature rupture of membranes	0.768	0.232
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.767	0.233
M13.96 Arthritis, unspecified (Lower leg)	0.766	0.234
H52.1 Myopia	0.763	0.237
G80-G83 Cerebral palsy and other paralytic syndromes	0.762	0.238
H46-H48 Disorders of optic nerve and visual pathways	0.758	0.242
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.757	0.243
S82.80 Fractures of other parts of lower leg (closed)	0.757	0.243
O16 Unspecified maternal hypertension	0.756	0.244
G62.8 Other specified polyneuropathies	0.755	0.245
B02 Zoster [herpes zoster]	0.753	0.247
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.753	0.247
H54 Blindness and low vision	0.751	0.249
S00.9 Superficial injury of head, part unspecified	0.748	0.252
O48 Prolonged pregnancy	0.748	0.252
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.745	0.255
O20 Haemorrhage in early pregnancy	0.740	0.260
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.737	0.263
S00.3 Superficial injury of nose	0.737	0.263
Chapter XXII Codes for special purposes	0.736	0.264
O36.0 Maternal care for rhesus isoimmunisation	0.734	0.265
H25-H28 Disorders of lens	0.733	0.267
S82.10 Fracture of upper end of tibia (closed)	0.733	0.267
A50-A64 Infections with a predominantly sexual mode of transmission	0.731	0.269
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.730	0.270
S06 Intracranial injury	0.730	0.270
G35-G37 Demyelinating diseases of the central nervous system	0.729	0.271
S09 Other and unspecified injuries of head	0.724	0.276
H55 Nystagmus and other irregular eye movements	0.724	0.276
T86 Failure and rejection of transplanted organs and tissues	0.723	0.277
G00-G09 Inflammatory diseases of the central nervous system	0.723	0.277
S32 Fracture of lumbar spine and pelvis	0.723	0.277
B15-B19 Viral hepatitis	0.721	0.279
G30-G32 Other degenerative diseases of the nervous system	0.721	0.279
O36.9 Maternal care for foetal problem, unspecified	0.721	0.279
H43-H45 Disorders of vitreous body and globe	0.718	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.716	0.284
H33.3 Retinal breaks without detachment	0.715	0.285
F40-F48 Neurotic, stress-related and somatoform disorders	0.714	0.286
G70-G73 Diseases of myoneural junction and muscle	0.712	0.288
H10-H13 Disorders of conjunctiva	0.711	0.289
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.710	0.290
O30 Multiple gestation	0.710	0.290
O70 Perineal laceration during delivery	0.709	0.291
G61 Inflammatory polyneuropathy	0.708	0.292
O34.1 Maternal care for tumour of corpus uteri	0.708	0.292
S82.2 Fracture of shaft of tibia	0.708	0.292
G90-G99 Other disorders of the nervous system	0.707	0.293
O45 Premature separation of placenta [abruptio placentae]	0.706	0.294
O44 Placenta praevia	0.706	0.294
O43 Placental disorders	0.706	0.294
O41 Other disorders of amniotic fluid and membranes	0.706	0.294
O35 Maternal care for known or suspected foetal abnormality and damage	0.706	0.294
O33 Maternal care for known or suspected disproportion	0.706	0.294
O31 Complications specific to multiple gestation	0.706	0.294
O40 Polyhydramnios	0.706	0.294
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.705	0.295
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.700	0.300
M91-M94 Chondropathies	0.700	0.300
M60-M63 Disorders of muscles	0.700	0.300
M00-M03 Infectious arthropathies	0.700	0.300
M47 Spondylosis	0.700	0.300
T88 Other complications of surgical and medical care, not elsewhere classified	0.699	0.301
M65 Synovitis and tenosynovitis	0.698	0.302
G62.9 Polyneuropathy, unspecified	0.697	0.303
M11 Other crystal arthropathies	0.697	0.303
O75 Other complications of labour and delivery, not elsewhere classified	0.694	0.306
M48 Other spondylopathies	0.694	0.306
O32.1 Maternal care for breech presentation	0.694	0.306
S88 Traumatic amputation of lower leg	0.693	0.306
S87 Crushing injury of lower leg	0.693	0.306
S86 Injury of muscle and tendon at lower leg level	0.693	0.306
S85 Injury of blood vessels at lower leg level	0.693	0.306
S84 Injury of nerves at lower leg level	0.693	0.306
S89 Other and unspecified injuries of lower leg	0.693	0.307
Chapter VIII Diseases of the ear and mastoid process	0.693	0.307
M13.98 Arthritis, unspecified (Other)	0.693	0.307
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.693	0.307
B99-B99 Other infectious diseases	0.692	0.308
B90-B94 Sequelae of infectious and parasitic diseases	0.692	0.308
B85-B89 Pediculosis, acariasis and other infestations	0.692	0.308
B65-B83 Helminthiases	0.692	0.308
B50-B64 Protozoal diseases	0.692	0.308
B20-B24 Human immunodeficiency virus [HIV] disease	0.692	0.308
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.692	0.308
A80-A89 Viral infections of the central nervous system	0.692	0.308
A75-A79 Rickettsioses	0.692	0.308
A70-A74 Other diseases caused by chlamydiae	0.692	0.308
A65-A69 Other spirochaetal diseases	0.692	0.308
A20-A28 Certain zoonotic bacterial diseases	0.692	0.308
A15-A19 Tuberculosis	0.692	0.308
T42.4 Benzodiazepines	0.692	0.308
O47 False labour	0.692	0.308
S01 Open wound of head	0.690	0.310
M87 Osteonecrosis	0.688	0.312
H52.0 Hypermetropia	0.688	0.312
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.687	0.312
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.687	0.312
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.312
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.687	0.312
T46 Poisoning by agents primarily affecting the cardiovascular system	0.687	0.312
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.687	0.312
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.687	0.312
T41 Poisoning by anaesthetics and therapeutic gases	0.687	0.312
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.687	0.312
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.687	0.312
T36 Poisoning by systemic antibiotics	0.687	0.312
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.686	0.313
G45 Transient cerebral ischaemic attacks and related syndromes	0.686	0.314
H50 Other strabismus	0.686	0.314
M40-M43 Deforming dorsopathies	0.684	0.315
M25.5 Pain in joint	0.684	0.316
S70-S79 Injuries to the hip and thigh	0.684	0.316
S50-S59 Injuries to the elbow and forearm	0.682	0.317
O04 Medical abortion	0.682	0.318
O20.0 Threatened abortion	0.682	0.318
O71 Other obstetric trauma	0.680	0.319
G57 Mononeuropathies of lower limb	0.678	0.322
Y86 Sequelae of other accidents	0.678	0.322
T39.0 Salicylates	0.678	0.322
O46 Antepartum haemorrhage, not elsewhere classified	0.676	0.324
S02 Fracture of skull and facial bones	0.676	0.324
S82.30 Fracture of lower end of tibia (closed)	0.675	0.325
G20-G26 Extrapyramidal and movement disorders	0.674	0.326
M05 Seropositive rheumatoid arthritis	0.673	0.327
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.673	0.327
S08 Traumatic amputation of part of head	0.670	0.330
S07 Crushing injury of head	0.670	0.330
S05 Injury of eye and orbit	0.670	0.330
S04 Injury of cranial nerves	0.670	0.330
S03 Dislocation, sprain and strain of joints and ligaments of head	0.670	0.330
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.667	0.333
A07 Other protozoal intestinal diseases	0.666	0.333
A06 Amoebiasis	0.666	0.333
A05 Other bacterial foodborne intoxications	0.666	0.333
A03 Shigellosis	0.666	0.333
A02 Other Salmonella infections	0.666	0.333
A01 Typhoid and paratyphoid fevers	0.666	0.333
A00 Cholera	0.666	0.333
M07.3 Other psoriatic arthropathies	0.665	0.335
O70.1 Second degree perineal laceration during delivery	0.664	0.336
S81 Open wound of lower leg	0.664	0.336
M14 Arthropathies in other diseases classified elsewhere	0.664	0.336
M12 Other specific arthropathies	0.664	0.336
M09 Juvenile arthritis in diseases classified elsewhere	0.664	0.336
M08 Juvenile arthritis	0.664	0.336
M25.6 Stiffness of joint, not elsewhere classified	0.662	0.338
T87 Complications peculiar to reattachment and amputation	0.662	0.338
T80 Complications following infusion, transfusion and therapeutic injection	0.662	0.338
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.662	0.338
T78 Adverse effects, not elsewhere classified	0.661	0.339
A08.4 Viral intestinal infection, unspecified	0.660	0.340
S82.9 Fracture of lower leg, part unspecified	0.659	0.341
S82.7 Multiple fractures of lower leg	0.659	0.341
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.659	0.341
O36.6 Maternal care for excessive foetal growth	0.659	0.341
O36.5 Maternal care for poor foetal growth	0.659	0.341
O36.4 Maternal care for intra-uterine death	0.659	0.341
O36.3 Maternal care for signs of foetal hypoxia	0.659	0.341
O36.2 Maternal care for hydrops foetalis	0.659	0.341
O36.1 Maternal care for other isoimmunisation	0.659	0.341
S40-S49 Injuries to the shoulder and upper arm	0.659	0.341
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.659	0.341
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.659	0.341
T39.4 Antirheumatics, not elsewhere classified	0.659	0.341
T39.2 Pyrazolone derivatives	0.659	0.341
S80.9 Superficial injury of lower leg, unspecified	0.658	0.341
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.658	0.342
M10 Gout	0.657	0.343
B25-B34 Other viral diseases	0.657	0.343
M13.91 Arthritis, unspecified (Shoulder region)	0.656	0.344
H32 Chorioretinal disorders in diseases classified elsewhere	0.655	0.344
H31 Other disorders of choroid	0.655	0.344
H30 Chorioretinal inflammation	0.655	0.344
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.655	0.345
F41 Other anxiety disorders	0.654	0.346
H51 Other disorders of binocular movement	0.652	0.348
H49 Paralytic strabismus	0.652	0.348
B02.9 Zoster without complication	0.651	0.349
S83.2 Tear of meniscus, current	0.651	0.349
H40 Glaucoma	0.649	0.351
W20-W49 Exposure to inanimate mechanical forces	0.648	0.352
G60 Hereditary and idiopathic neuropathy	0.647	0.353
G64 Other disorders of peripheral nervous system	0.647	0.353
O80-O84 Delivery	0.647	0.353
T81.4 Infection following a procedure, not elsewhere classified	0.647	0.353
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.647	0.353
O72 Postpartum haemorrhage	0.645	0.355
S82.0 Fracture of patella	0.645	0.355
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.645	0.355
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.645	0.355
G56 Mononeuropathies of upper limb	0.645	0.355
S82.4 Fracture of fibula alone	0.645	0.355
Chapter II Neoplasms	0.645	0.355
M13.97 Arthritis, unspecified (Ankle and foot)	0.644	0.356
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.643	0.357
H34 Retinal vascular occlusions	0.642	0.358
M25.78 Osteophyte (Other)	0.642	0.358
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.641	0.359
B06 Rubella [German measles]	0.641	0.359
B05 Measles	0.641	0.359
B01 Varicella [chickenpox]	0.641	0.359
B00 Herpesviral [herpes simplex] infections	0.641	0.359
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.641	0.359
B04 Monkeypox	0.641	0.359
B03 Smallpox	0.641	0.359
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.641	0.359
O34.8 Maternal care for other abnormalities of pelvic organs	0.641	0.359
O34.7 Maternal care for abnormality of vulva and perineum	0.641	0.359
O34.6 Maternal care for abnormality of vagina	0.641	0.359
O34.5 Maternal care for other abnormalities of gravid uterus	0.641	0.359
O34.4 Maternal care for other abnormalities of cervix	0.641	0.359
O34.3 Maternal care for cervical incompetence	0.641	0.359
O34.0 Maternal care for congenital malformation of uterus	0.641	0.359
H33.5 Other retinal detachments	0.640	0.360
H33.4 Traction detachment of retina	0.640	0.360
H33.1 Retinoschisis and retinal cysts	0.640	0.360
G63 Polyneuropathy in diseases classified elsewhere	0.639	0.361
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.638	0.362
O00 Ectopic pregnancy	0.638	0.362
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.637	0.363
M31 Other necrotising vasculopathies	0.637	0.363
H54.9 Unspecified visual impairment (binocular)	0.635	0.365
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.634	0.365
O97 Death from sequelae of direct obstetric causes	0.634	0.365
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.634	0.365
O95 Obstetric death of unspecified cause	0.634	0.365
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.634	0.365
V10-V19 Pedal cyclist injured in transport accident	0.634	0.366
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.633	0.367
M90 Osteopathies in diseases classified elsewhere	0.632	0.368
M67 Other disorders of synovium and tendon	0.632	0.368
O15 Eclampsia	0.631	0.369
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.631	0.369
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.631	0.369
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.631	0.369
M25.4 Effusion of joint	0.629	0.371
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.627	0.372
S82.5 Fracture of medial malleolus	0.626	0.374
M13.8 Other specified arthritis	0.625	0.375
M13.1 Monoarthritis, not elsewhere classified	0.625	0.375
M13.0 Polyarthritis, unspecified	0.625	0.375
M13.90 Arthritis, unspecified (Multiple sites)	0.624	0.376
M13.94 Arthritis, unspecified (Hand)	0.622	0.378
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.622	0.378
S37 Injury of urinary and pelvic organs	0.622	0.378
S36 Injury of intra-abdominal organs	0.622	0.378
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.622	0.378
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.622	0.378
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.622	0.378
S31 Open wound of abdomen, lower back and pelvis	0.622	0.378
S30 Superficial injury of abdomen, lower back and pelvis	0.622	0.378
O63 Long labour	0.621	0.379
S90 Superficial injury of ankle and foot	0.621	0.379
O69 Labour and delivery complicated by umbilical cord complications	0.620	0.380
H54.0 Blindness, both eyes	0.619	0.381
Q60-Q64 Congenital malformations of the urinary system	0.619	0.381
M25.76 Osteophyte (Lower leg)	0.619	0.381
M65.3 Trigger finger	0.616	0.384
O74 Complications of anaesthesia during labour and delivery	0.614	0.385
O73 Retained placenta and membranes, without haemorrhage	0.614	0.385
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.614	0.385
O66 Other obstructed labour	0.614	0.385
O65 Obstructed labour due to maternal pelvic abnormality	0.614	0.385
O64 Obstructed labour due to malposition and malpresentation of foetus	0.614	0.385
O62 Abnormalities of forces of labour	0.614	0.385
O61 Failed induction of labour	0.614	0.385
O60 Preterm delivery	0.614	0.385
H54.4 Blindness, one eye	0.614	0.386
S00.1 Contusion of eyelid and periocular area	0.613	0.387
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.612	0.388
M34 Systemic sclerosis	0.612	0.388
M33 Dermatopolymyositis	0.612	0.388
M32 Systemic lupus erythematosus	0.612	0.388
M30 Polyarteritis nodosa and related conditions	0.612	0.388
O42.9 Premature rupture of membranes, unspecified	0.612	0.388
O26 Maternal care for other conditions predominantly related to pregnancy	0.611	0.389
T18 Foreign body in alimentary tract	0.610	0.390
S00.7 Multiple superficial injuries of head	0.610	0.390
S00.5 Superficial injury of lip and oral cavity	0.610	0.390
S00.4 Superficial injury of ear	0.610	0.390
S00.2 Other superficial injuries of eyelid and periocular area	0.610	0.390
S00.0 Superficial injury of scalp	0.610	0.390
Chapter XI Diseases of the digestive system	0.610	0.390
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.610	0.390
O29 Complications of anaesthesia during pregnancy	0.609	0.391
O28 Abnormal findings on antenatal screening of mother	0.609	0.391
O24 Diabetes mellitus in pregnancy	0.609	0.391
O23 Infections of genito-urinary tract in pregnancy	0.609	0.391
O22 Venous complications in pregnancy	0.609	0.391
O21 Excessive vomiting in pregnancy	0.609	0.391
O25 Malnutrition in pregnancy	0.609	0.391
B95-B98 Bacterial, viral and other infectious agents	0.608	0.392
M80 Osteoporosis with pathological fracture	0.607	0.392
Y60-Y69 Misadventures to patients during surgical and medical care	0.606	0.394
W00-W19 Falls	0.606	0.394
M47.9 Spondylosis, unspecified	0.606	0.394
M49 Spondylopathies in diseases classified elsewhere	0.605	0.395
M89 Other disorders of bone	0.604	0.396
O03 Spontaneous abortion	0.604	0.396
M25.9 Joint disorder, unspecified	0.603	0.397
M25.8 Other specified joint disorders	0.603	0.397
M25.3 Other instability of joint	0.603	0.397
M25.2 Flail joint	0.603	0.397
M25.1 Fistula of joint	0.603	0.397
M25.0 Haemarthrosis	0.603	0.397
H52.7 Disorder of refraction, unspecified	0.602	0.397
H52.6 Other disorders of refraction	0.602	0.397
H52.5 Disorders of accommodation	0.602	0.397
H52.4 Presbyopia	0.602	0.397
H52.3 Anisometropia and aniseikonia	0.602	0.397
H52.2 Astigmatism	0.602	0.397
M45 Ankylosing spondylitis	0.602	0.398
S22 Fracture of rib(s), sternum and thoracic spine	0.602	0.398
M85 Other disorders of bone density and structure	0.601	0.398
M21 Other acquired deformities of limbs	0.600	0.400
G57.6 Lesion of plantar nerve	0.600	0.400
M24 Other specific joint derangements	0.600	0.400
G62.2 Polyneuropathy due to other toxic agents	0.599	0.400
G62.1 Alcoholic polyneuropathy	0.599	0.400
G62.0 Drug-induced polyneuropathy	0.599	0.400
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.600	0.400
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.599	0.401
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.599	0.401
H57 Other disorders of eye and adnexa	0.599	0.401
H36 Retinal disorders in diseases classified elsewhere	0.599	0.401
G80 Infantile cerebral palsy	0.597	0.403
M13.93 Arthritis, unspecified (Forearm)	0.596	0.403
M13.92 Arthritis, unspecified (Upper arm)	0.596	0.403
M22 Disorders of patella	0.596	0.404
S91 Open wound of ankle and foot	0.595	0.405
M25.54 Pain in joint (Hand)	0.595	0.405
Y35-Y36 Legal intervention and operations of war	0.594	0.406
Y10-Y34 Event of undetermined intent	0.594	0.406
Y00-Y09 Assault	0.594	0.406
X85-X99 Assault	0.594	0.406
X58-X59 Accidental exposure to other and unspecified factors	0.594	0.406
X50-X57 Overexertion, travel and privation	0.594	0.406
X40-X49 Accidental poisoning by and exposure to noxious substances	0.594	0.406
X30-X39 Exposure to forces of nature	0.594	0.406
X20-X29 Contact with venomous animals and plants	0.594	0.406
X10-X19 Contact with heat and hot substances	0.594	0.406
X00-X09 Exposure to smoke, fire and flames	0.594	0.406
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.594	0.406
W75-W84 Other accidental threats to breathing	0.594	0.406
W65-W74 Accidental drowning and submersion	0.594	0.406
W50-W64 Exposure to animate mechanical forces	0.594	0.406
V98-V99 Other and unspecified transport accidents	0.594	0.406
V95-V97 Air and space transport accidents	0.594	0.406
V90-V94 Water transport accidents	0.594	0.406
V80-V89 Other land transport accidents	0.594	0.406
V70-V79 Bus occupant injured in transport accident	0.594	0.406
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.594	0.406
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.594	0.406
V40-V49 Car occupant injured in transport accident	0.594	0.406
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.594	0.406
V20-V29 Motorcycle rider injured in transport accident	0.594	0.406
V01-V09 Pedestrian injured in transport accident	0.594	0.406
M46 Other inflammatory spondylopathies	0.594	0.406
H40.0 Glaucoma suspect	0.593	0.407
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.593	0.407
M66 Spontaneous rupture of synovium and tendon	0.593	0.407
M88 Paget's disease of bone [osteitis deformans]	0.592	0.408
M86 Osteomyelitis	0.592	0.408
S82.86 Maisonneuve's fracture	0.591	0.409
S82.81 Fractures of other parts of lower leg (open)	0.591	0.409
Chapter X Diseases of the respiratory system	0.591	0.409
O04.9 Complete or unspecified, without complication	0.591	0.409
X60-X84 Intentional self-harm	0.590	0.409
M35 Other systemic involvement of connective tissue	0.590	0.410
H46 Optic neuritis	0.590	0.410
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.590	0.410
T93 Sequelae of injuries of lower limb	0.590	0.410
G45.4 Transient global amnesia	0.590	0.410
M84 Disorders of continuity of bone	0.590	0.410
M25.79 Osteophyte (Site unspecified)	0.589	0.411
M25.73 Osteophyte (Forearm)	0.589	0.411
M25.72 Osteophyte (Upper arm)	0.589	0.411
M25.71 Osteophyte (Shoulder region)	0.589	0.411
M25.70 Osteophyte (Multiple sites)	0.589	0.411
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.588	0.411
M48.0 Spinal stenosis	0.587	0.412
M06 Other rheumatoid arthritis	0.586	0.414
T85.4 Mechanical complication of breast prosthesis and implant	0.586	0.414
G43 Migraine	0.586	0.414
Q20-Q28 Congenital malformations of the circulatory system	0.585	0.414
T81.8 Other complications of procedures, not elsewhere classified	0.585	0.415
M25.74 Osteophyte (Hand)	0.585	0.415
O32.9 Maternal care for malpresentation of foetus, unspecified	0.585	0.415
O32.8 Maternal care for other malpresentation of foetus	0.585	0.415
O32.6 Maternal care for compound presentation	0.585	0.415
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.585	0.415
O32.4 Maternal care for high head at term	0.585	0.415
O32.3 Maternal care for face, brow and chin presentation	0.585	0.415
O32.2 Maternal care for transverse and oblique lie	0.585	0.415
O32.0 Maternal care for unstable lie	0.585	0.415
J30-J39 Other diseases of upper respiratory tract	0.585	0.415
M87.2 Osteonecrosis due to previous trauma	0.584	0.416
H25 Senile cataract	0.584	0.416
G37 Other demyelinating diseases of central nervous system	0.583	0.417
T81.9 Unspecified complication of procedure	0.582	0.417
T81.7 Vascular complications following a procedure, not elsewhere classified	0.582	0.417
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.582	0.417
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.582	0.417
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.582	0.417
A04 Other bacterial intestinal infections	0.582	0.418
M50-M54 Other dorsopathies	0.582	0.418
S82.11 Fracture of upper end of tibia (open)	0.581	0.418
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.580	0.420
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.580	0.420
T85.2 Mechanical complication of intraocular lens	0.580	0.420
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.580	0.420
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.580	0.420
O08 Complications following abortion and ectopic and molar pregnancy	0.580	0.420
O07 Failed attempted abortion	0.580	0.420
O06 Unspecified abortion	0.580	0.420

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations