TreeWAS – Variant ID: rs192256367

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
K20-K31 Diseases of oesophagus, stomach and duodenum	0.003	0.997
Chapter XI Diseases of the digestive system	0.003	0.997
# Top node	0.003	0.997
K22 Other diseases of oesophagus	0.002	0.997
Chapter IX Diseases of the circulatory system	0.002	0.997
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.002	0.997
K29 Gastritis and duodenitis	0.002	0.997
K20 Oesophagitis	0.002	0.998
K40-K46 Hernia	0.002	0.998
Chapter VII Diseases of the eye and adnexa	0.002	0.998
K31 Other diseases of stomach and duodenum	0.002	0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.002	0.998
K26 Duodenal ulcer	0.002	0.998
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.002	0.998
Chapter V Mental and behavioural disorders	0.002	0.998
K22.7 Barrett's oesophagus	0.002	0.998
K21 Gastro-oesophageal reflux disease	0.002	0.998
I20-I25 Ischaemic heart diseases	0.002	0.998
I10-I15 Hypertensive diseases	0.002	0.998
K22.1 Ulcer of oesophagus	0.002	0.998
K90-K93 Other diseases of the digestive system	0.002	0.998
K70-K77 Diseases of liver	0.002	0.998
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.002	0.998
Chapter X Diseases of the respiratory system	0.002	0.998
K28 Gastrojejunal ulcer	0.002	0.998
K27 Peptic ulcer, site unspecified	0.002	0.998
K23 Disorders of oesophagus in diseases classified elsewhere	0.002	0.998
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998
Chapter XII Diseases of the skin and subcutaneous tissue	0.002	0.998
K25 Gastric ulcer	0.002	0.998
K65-K67 Diseases of peritoneum	0.002	0.998
K35-K38 Diseases of appendix	0.002	0.998
Chapter XXII Codes for special purposes	0.002	0.998
Chapter XX External causes of morbidity and mortality	0.002	0.998
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998
Chapter XVI Certain conditions originating in the perinatal period	0.002	0.998
Chapter VI Diseases of the nervous system	0.002	0.998
K55-K64 Other diseases of intestines	0.002	0.998
K50-K52 Noninfective enteritis and colitis	0.002	0.998
Chapter XV Pregnancy, childbirth and the puerperium	0.002	0.998
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998
I30-I52 Other forms of heart disease	0.002	0.998
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.002	0.998
Chapter I Certain infectious and parasitic diseases	0.002	0.998
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998
Chapter XIV Diseases of the genitourinary system	0.002	0.998
K29.5 Chronic gastritis, unspecified	0.002	0.998
K30 Dyspepsia	0.002	0.998
K29.6 Other gastritis	0.002	0.998
R30-R39 Symptoms and signs involving the urinary system	0.002	0.998
K29.8 Duodenitis	0.002	0.998
I10 Essential (primary) hypertension	0.002	0.998
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.002	0.998
R50-R69 General symptoms and signs	0.002	0.998
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.002	0.998
K22.9 Disease of oesophagus, unspecified	0.002	0.998
K22.8 Other specified diseases of oesophagus	0.002	0.998
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.002	0.998
K22.5 Diverticulum of oesophagus, acquired	0.002	0.998
K22.4 Dyskinesia of oesophagus	0.002	0.998
K22.3 Perforation of oesophagus	0.002	0.998
K22.2 Oesophageal obstruction	0.002	0.998
K22.0 Achalasia of cardia	0.002	0.998
I05-I09 Chronic rheumatic heart diseases	0.002	0.998
I00-I02 Acute rheumatic fever	0.002	0.998
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.002	0.998
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998
I60-I69 Cerebrovascular diseases	0.002	0.998
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998
R95-R99 Ill-defined and unknown causes of mortality	0.002	0.998
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.002	0.998
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998
Chapter XXI Factors influencing health status and contact with health services	0.002	0.998
Chapter II Neoplasms	0.002	0.998
K44 Diaphragmatic hernia	0.002	0.998
H30-H36 Disorders of choroid and retina	0.002	0.998
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.002	0.998
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.002	0.998
K29.9 Gastroduodenitis, unspecified	0.002	0.998
K29.4 Chronic atrophic gastritis	0.002	0.998
K29.3 Chronic superficial gastritis	0.002	0.998
K29.2 Alcoholic gastritis	0.002	0.998
K29.1 Other acute gastritis	0.002	0.998
K29.0 Acute haemorrhagic gastritis	0.002	0.998
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.002	0.998
K29.7 Gastritis, unspecified	0.002	0.998
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.002	0.998
R10 Abdominal and pelvic pain	0.002	0.998
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.002	0.998
J40-J47 Chronic lower respiratory diseases	0.002	0.998
M70-M79 Other soft tissue disorders	0.002	0.998
I25 Chronic ischaemic heart disease	0.002	0.998
I20 Angina pectoris	0.002	0.998
R19 Other symptoms and signs involving the digestive system and abdomen	0.002	0.998
M20-M25 Other joint disorders	0.002	0.998
K31.8 Other specified diseases of stomach and duodenum	0.002	0.998
K31.7 Polyp of stomach and duodenum	0.002	0.998
K43 Ventral hernia	0.002	0.998
R14 Flatulence and related conditions	0.002	0.998
R11 Nausea and vomiting	0.002	0.998
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.002	0.998
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998
I21 Acute myocardial infarction	0.002	0.998
K46 Unspecified abdominal hernia	0.002	0.998
K45 Other abdominal hernia	0.002	0.998
K41 Femoral hernia	0.002	0.998
R13 Dysphagia	0.002	0.998
F30-F39 Mood [affective] disorders	0.002	0.998
H55-H59 Other disorders of eye and adnexa	0.002	0.998
H53-H54 Visual disturbances and blindness	0.002	0.998
H46-H48 Disorders of optic nerve and visual pathways	0.002	0.998
H43-H45 Disorders of vitreous body and globe	0.002	0.998
H25-H28 Disorders of lens	0.002	0.998
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998
H10-H13 Disorders of conjunctiva	0.002	0.998
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998
K31.6 Fistula of stomach and duodenum	0.002	0.998
K31.5 Obstruction of duodenum	0.002	0.998
K31.4 Gastric diverticulum	0.002	0.998
K31.3 Pylorospasm, not elsewhere classified	0.002	0.998
K31.2 Hourglass stricture and stenosis of stomach	0.002	0.998
K31.1 Adult hypertrophic pyloric stenosis	0.002	0.998
K31.0 Acute dilatation of stomach	0.002	0.998
K04 Diseases of pulp and periapical tissues	0.002	0.998
K02 Dental caries	0.002	0.998
K42 Umbilical hernia	0.002	0.998
K63 Other diseases of intestine	0.002	0.998
K76 Other diseases of liver	0.002	0.998
K90 Intestinal malabsorption	0.002	0.998
F99-F99 Unspecified mental disorder	0.002	0.998
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998
F80-F89 Disorders of psychological development	0.002	0.998
F70-F79 Mental retardation	0.002	0.998
F60-F69 Disorders of adult personality and behaviour	0.002	0.998
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998
H40-H42 Glaucoma	0.002	0.998
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.998
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.002	0.998
M91-M94 Chondropathies	0.002	0.998
M86-M90 Other osteopathies	0.002	0.998
M80-M85 Disorders of bone density and structure	0.002	0.998
M65-M68 Disorders of synovium and tendon	0.002	0.998
M60-M63 Disorders of muscles	0.002	0.998
M50-M54 Other dorsopathies	0.002	0.998
M40-M43 Deforming dorsopathies	0.002	0.998
M00-M03 Infectious arthropathies	0.002	0.998
K26.7 Chronic without haemorrhage or perforation	0.002	0.998
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998
K26.5 Chronic or unspecified with perforation	0.002	0.998
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998
K26.3 Acute without haemorrhage or perforation	0.002	0.998
K26.2 Acute with both haemorrhage and perforation	0.002	0.998
K26.1 Acute with perforation	0.002	0.998
K26.0 Acute with haemorrhage	0.002	0.998
I15 Secondary hypertension	0.002	0.998
I13 Hypertensive heart and renal disease	0.002	0.998
I12 Hypertensive renal disease	0.002	0.998
I11 Hypertensive heart disease	0.002	0.998
K40 Inguinal hernia	0.002	0.998
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998
R18 Ascites	0.002	0.998
R17 Unspecified jaundice	0.002	0.998
R15 Faecal incontinence	0.002	0.998
E70-E90 Metabolic disorders	0.002	0.998
E65-E68 Obesity and other hyperalimentation	0.002	0.998
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998
J20-J22 Other acute lower respiratory infections	0.002	0.998
L60-L75 Disorders of skin appendages	0.002	0.998
M45-M49 Spondylopathies	0.002	0.998
M15-M19 Arthrosis	0.002	0.998
M05-M14 Inflammatory polyarthropathies	0.002	0.998
I24 Other acute ischaemic heart diseases	0.002	0.998
I23 Certain current complications following acute myocardial infarction	0.002	0.998
I22 Subsequent myocardial infarction	0.002	0.998
I50 Heart failure	0.002	0.998
K14 Diseases of tongue	0.002	0.998
K13 Other diseases of lip and oral mucosa	0.002	0.998
K12 Stomatitis and related lesions	0.002	0.998
K11 Diseases of salivary glands	0.002	0.998
K10 Other diseases of jaws	0.002	0.998
K09 Cysts of oral region, not elsewhere classified	0.002	0.998
K08 Other disorders of teeth and supporting structures	0.002	0.998
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998
K06 Other disorders of gingiva and edentulous alveolar ridge	0.002	0.998
K05 Gingivitis and periodontal diseases	0.002	0.998
K03 Other diseases of hard tissues of teeth	0.002	0.998
K01 Embedded and impacted teeth	0.002	0.998
K00 Disorders of tooth development and eruption	0.002	0.998
K77 Liver disorders in diseases classified elsewhere	0.002	0.998
K75 Other inflammatory liver diseases	0.002	0.998
K74 Fibrosis and cirrhosis of liver	0.002	0.998
K73 Chronic hepatitis, not elsewhere classified	0.002	0.998
K72 Hepatic failure, not elsewhere classified	0.002	0.998
K71 Toxic liver disease	0.002	0.998
K70 Alcoholic liver disease	0.002	0.998
K93 Disorders of other digestive organs in diseases classified elsewhere	0.002	0.998
K92 Other diseases of digestive system	0.002	0.998
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998
R12 Heartburn	0.002	0.998
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998
J95-J99 Other diseases of the respiratory system	0.002	0.998
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.002	0.998
J80-J84 Other respiratory diseases principally affecting the interstitium	0.002	0.998
J60-J70 Lung diseases due to external agents	0.002	0.998
J09-J18 Influenza and pneumonia	0.002	0.998
J00-J06 Acute upper respiratory infections	0.002	0.998
N20-N23 Urolithiasis	0.002	0.998
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.002	0.998
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.002	0.998
K23.1 Megaoesophagus in Chagas' disease	0.002	0.998
K23.0 Tuberculous oesophagitis	0.002	0.998
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998
K27.7 Chronic without haemorrhage or perforation	0.002	0.998
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998
K27.5 Chronic or unspecified with perforation	0.002	0.998
K27.4 Chronic or unspecified with haemorrhage	0.002	0.998
K27.3 Acute without haemorrhage or perforation	0.002	0.998
K27.2 Acute with both haemorrhage and perforation	0.002	0.998
K27.1 Acute with perforation	0.002	0.998
K27.0 Acute with haemorrhage	0.002	0.998
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998
K28.7 Chronic without haemorrhage or perforation	0.002	0.998
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998
K28.5 Chronic or unspecified with perforation	0.002	0.998
K28.4 Chronic or unspecified with haemorrhage	0.002	0.998
K28.3 Acute without haemorrhage or perforation	0.002	0.998
K28.2 Acute with both haemorrhage and perforation	0.002	0.998
K28.1 Acute with perforation	0.002	0.998
K28.0 Acute with haemorrhage	0.002	0.998
I47 Paroxysmal tachycardia	0.002	0.998
I34 Nonrheumatic mitral valve disorders	0.002	0.998
K51 Ulcerative colitis	0.002	0.998
K62 Other diseases of anus and rectum	0.002	0.998
E50-E64 Other nutritional deficiencies	0.002	0.998
E40-E46 Malnutrition	0.002	0.998
E20-E35 Disorders of other endocrine glands	0.002	0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998
E10-E14 Diabetes mellitus	0.002	0.998
E00-E07 Disorders of thyroid gland	0.002	0.998
G50-G59 Nerve, nerve root and plexus disorders	0.002	0.998
J90-J94 Other diseases of pleura	0.002	0.998
L50-L54 Urticaria and erythema	0.002	0.998
L10-L14 Bullous disorders	0.002	0.998
L00-L08 Infections of the skin and subcutaneous tissue	0.002	0.998
O80-O84 Delivery	0.002	0.998
W00-W19 Falls	0.002	0.998
K25.7 Chronic without haemorrhage or perforation	0.002	0.998
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998
K25.5 Chronic or unspecified with perforation	0.002	0.998
K25.4 Chronic or unspecified with haemorrhage	0.002	0.998
K25.3 Acute without haemorrhage or perforation	0.002	0.998
K25.2 Acute with both haemorrhage and perforation	0.002	0.998
K25.1 Acute with perforation	0.002	0.998
K25.0 Acute with haemorrhage	0.002	0.998
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.002	0.998
I44 Atrioventricular and left bundle-branch block	0.002	0.998
K38 Other diseases of appendix	0.002	0.998
K35 Acute appendicitis	0.002	0.998
K37 Unspecified appendicitis	0.002	0.998
K36 Other appendicitis	0.002	0.998
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.002	0.998
K65 Peritonitis	0.002	0.998
R69 Unknown and unspecified causes of morbidity	0.002	0.998
D50-D53 Nutritional anaemias	0.002	0.998
G90-G99 Other disorders of the nervous system	0.002	0.998
G80-G83 Cerebral palsy and other paralytic syndromes	0.002	0.998
G70-G73 Diseases of myoneural junction and muscle	0.002	0.998
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998
G20-G26 Extrapyramidal and movement disorders	0.002	0.998
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.002	0.998
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998
J30-J39 Other diseases of upper respiratory tract	0.002	0.998
L80-L99 Other disorders of the skin and subcutaneous tissue	0.002	0.998
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.002	0.998
L40-L45 Papulosquamous disorders	0.002	0.998
L20-L30 Dermatitis and eczema	0.002	0.998
N17-N19 Renal failure	0.002	0.998
P90-P96 Other disorders originating in the perinatal period	0.002	0.998
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.002	0.998
P75-P78 Digestive system disorders of fetus and newborn	0.002	0.998
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.002	0.998
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.002	0.998
P35-P39 Infections specific to the perinatal period	0.002	0.998
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.002	0.998
P10-P15 Birth trauma	0.002	0.998
P05-P08 Disorders related to length of gestation and fetal growth	0.002	0.998
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.002	0.998
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998
Q80-Q89 Other congenital malformations	0.002	0.998
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998
Q50-Q56 Congenital malformations of genital organs	0.002	0.998
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998
Q35-Q37 Cleft lip and cleft palate	0.002	0.998
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998
Y35-Y36 Legal intervention and operations of war	0.002	0.998
Y10-Y34 Event of undetermined intent	0.002	0.998
Y00-Y09 Assault	0.002	0.998
X85-X99 Assault	0.002	0.998
X60-X84 Intentional self-harm	0.002	0.998
X58-X59 Accidental exposure to other and unspecified factors	0.002	0.998
X50-X57 Overexertion, travel and privation	0.002	0.998
X40-X49 Accidental poisoning by and exposure to noxious substances	0.002	0.998
X30-X39 Exposure to forces of nature	0.002	0.998
X20-X29 Contact with venomous animals and plants	0.002	0.998
X10-X19 Contact with heat and hot substances	0.002	0.998
X00-X09 Exposure to smoke, fire and flames	0.002	0.998
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.002	0.998
W75-W84 Other accidental threats to breathing	0.002	0.998
W65-W74 Accidental drowning and submersion	0.002	0.998
W50-W64 Exposure to animate mechanical forces	0.002	0.998
W20-W49 Exposure to inanimate mechanical forces	0.002	0.998
V98-V99 Other and unspecified transport accidents	0.002	0.998
V95-V97 Air and space transport accidents	0.002	0.998
V90-V94 Water transport accidents	0.002	0.998
V80-V89 Other land transport accidents	0.002	0.998
V70-V79 Bus occupant injured in transport accident	0.002	0.998
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.002	0.998
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.002	0.998
V40-V49 Car occupant injured in transport accident	0.002	0.998
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.002	0.998
V20-V29 Motorcycle rider injured in transport accident	0.002	0.998
V10-V19 Pedal cyclist injured in transport accident	0.002	0.998
V01-V09 Pedestrian injured in transport accident	0.002	0.998
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.002	0.998
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998
H33 Retinal detachments and breaks	0.002	0.998
I52 Other heart disorders in diseases classified elsewhere	0.002	0.998
I48 Atrial fibrillation and flutter	0.002	0.998
I46 Cardiac arrest	0.002	0.998
I43 Cardiomyopathy in diseases classified elsewhere	0.002	0.998
I42 Cardiomyopathy	0.002	0.998
I41 Myocarditis in diseases classified elsewhere	0.002	0.998
I40 Acute myocarditis	0.002	0.998
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.998
I37 Pulmonary valve disorders	0.002	0.998
I36 Nonrheumatic tricuspid valve disorders	0.002	0.998
I33 Acute and subacute endocarditis	0.002	0.998
I32 Pericarditis in diseases classified elsewhere	0.002	0.998
I31 Other diseases of pericardium	0.002	0.998
I30 Acute pericarditis	0.002	0.998
I38 Endocarditis, valve unspecified	0.002	0.998
K50 Crohn's disease [regional enteritis]	0.002	0.998
K64 Haemorrhoids and perianal venous thrombosis	0.002	0.998
K61 Abscess of anal and rectal regions	0.002	0.998
K59 Other functional intestinal disorders	0.002	0.998
K55 Vascular disorders of intestine	0.002	0.998
K66 Other disorders of peritoneum	0.002	0.998
R80 Isolated proteinuria	0.002	0.998
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998
D60-D64 Aplastic and other anaemias	0.002	0.998
D55-D59 Haemolytic anaemias	0.002	0.998
H90-H95 Other disorders of ear	0.002	0.998
H80-H83 Diseases of inner ear	0.002	0.998
H65-H75 Diseases of middle ear and mastoid	0.002	0.998
H60-H62 Diseases of external ear	0.002	0.998
N80-N98 Noninflammatory disorders of female genital tract	0.002	0.998
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998
S60-S69 Injuries to the wrist and hand	0.002	0.998
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998
O85-O92 Complications predominantly related to the puerperium	0.002	0.998
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998
O00-O08 Pregnancy with abortive outcome	0.002	0.998
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.002	0.998
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998
I49 Other cardiac arrhythmias	0.002	0.998
I45 Other conduction disorders	0.002	0.998
I35 Nonrheumatic aortic valve disorders	0.002	0.998
K60 Fissure and fistula of anal and rectal regions	0.002	0.998
K58 Irritable bowel syndrome	0.002	0.998
K56 Paralytic ileus and intestinal obstruction without hernia	0.002	0.998
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.002	0.998
K86 Other diseases of pancreas	0.002	0.998
K85 Acute pancreatitis	0.002	0.998
K83 Other diseases of biliary tract	0.002	0.998
K82 Other diseases of gallbladder	0.002	0.998
K81 Cholecystitis	0.002	0.998
R00 Abnormalities of heart beat	0.002	0.998
R39 Other symptoms and signs involving the urinary system	0.002	0.998
R35 Polyuria	0.002	0.998
R31 Unspecified haematuria	0.002	0.998
R53 Malaise and fatigue	0.002	0.998
B99-B99 Other infectious diseases	0.002	0.998
B95-B98 Bacterial, viral and other infectious agents	0.002	0.998
B90-B94 Sequelae of infectious and parasitic diseases	0.002	0.998
B85-B89 Pediculosis, acariasis and other infestations	0.002	0.998
B65-B83 Helminthiases	0.002	0.998
B50-B64 Protozoal diseases	0.002	0.998
B35-B49 Mycoses	0.002	0.998
B25-B34 Other viral diseases	0.002	0.998
B20-B24 Human immunodeficiency virus [HIV] disease	0.002	0.998
B15-B19 Viral hepatitis	0.002	0.998
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.002	0.998
A80-A89 Viral infections of the central nervous system	0.002	0.998
A75-A79 Rickettsioses	0.002	0.998
A70-A74 Other diseases caused by chlamydiae	0.002	0.998
A65-A69 Other spirochaetal diseases	0.002	0.998
A50-A64 Infections with a predominantly sexual mode of transmission	0.002	0.998
A30-A49 Other bacterial diseases	0.002	0.998
A20-A28 Certain zoonotic bacterial diseases	0.002	0.998
A15-A19 Tuberculosis	0.002	0.998
G40-G47 Episodic and paroxysmal disorders	0.002	0.998
N99-N99 Other disorders of the genitourinary system	0.002	0.998
N00-N08 Glomerular diseases	0.002	0.998
O60-O75 Complications of labour and delivery	0.002	0.998
K80 Cholelithiasis	0.002	0.998
R33 Retention of urine	0.002	0.998
R63 Symptoms and signs concerning food and fluid intake	0.002	0.998
R51 Headache	0.002	0.998
A00-A09 Intestinal infectious diseases	0.002	0.998
N70-N77 Inflammatory diseases of female pelvic organs	0.002	0.998
N60-N64 Disorders of breast	0.002	0.998
N25-N29 Other disorders of kidney and ureter	0.002	0.998
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998
T79-T79 Certain early complications of trauma	0.002	0.998
T66-T78 Other and unspecified effects of external causes	0.002	0.998
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998
T33-T35 Frostbite	0.002	0.998
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998
T00-T07 Injuries involving multiple body regions	0.002	0.998
S90-S99 Injuries to the ankle and foot	0.002	0.998
S80-S89 Injuries to the knee and lower leg	0.002	0.998
S70-S79 Injuries to the hip and thigh	0.002	0.998
S50-S59 Injuries to the elbow and forearm	0.002	0.998
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998
S20-S29 Injuries to the thorax	0.002	0.998
S10-S19 Injuries to the neck	0.002	0.998
S00-S09 Injuries to the head	0.002	0.998
J44 Other chronic obstructive pulmonary disease	0.002	0.998
K52 Other non-infective gastro-enteritis and colitis	0.002	0.998
M75 Shoulder lesions	0.002	0.998
R07 Pain in throat and chest	0.002	0.998
R30 Pain associated with micturition	0.002	0.998
R36 Urethral discharge	0.002	0.998
R34 Anuria and oliguria	0.002	0.998
R68 Other general symptoms and signs	0.002	0.998
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.002	0.998
R62 Lack of expected normal physiological development	0.002	0.998
R61 Hyperhidrosis	0.002	0.998
R57 Shock, not elsewhere classified	0.002	0.998
R52 Pain, not elsewhere classified	0.002	0.998
R64 Cachexia	0.002	0.998
R58 Haemorrhage, not elsewhere classified	0.002	0.998
R54 Senility	0.002	0.998
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998
I25.8 Other forms of chronic ischaemic heart disease	0.002	0.998
M20 Acquired deformities of fingers and toes	0.002	0.998
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.002	0.998
R06 Abnormalities of breathing	0.002	0.998
R01 Cardiac murmurs and other cardiac sounds	0.002	0.998
R02 Gangrene, not elsewhere classified	0.002	0.998
R32 Unspecified urinary incontinence	0.002	0.998
R60 Oedema, not elsewhere classified	0.002	0.998
R59 Enlarged lymph nodes	0.002	0.998
R56 Convulsions, not elsewhere classified	0.002	0.998
R50 Fever of unknown origin	0.002	0.998
R82 Other abnormal findings in urine	0.002	0.998
R81 Glycosuria	0.002	0.998
Z70-Z76 Persons encountering health services in other circumstances	0.002	0.998
H35 Other retinal disorders	0.002	0.998
R04 Haemorrhage from respiratory passages	0.002	0.998
R03 Abnormal blood-pressure reading, without diagnosis	0.002	0.998
R05 Cough	0.002	0.998
R79 Other abnormal findings of blood chemistry	0.002	0.998
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998
I20.0 Unstable angina	0.002	0.998
R10.1 Pain localised to upper abdomen	0.002	0.998
I02 Rheumatic chorea	0.002	0.998
I01 Rheumatic fever with heart involvement	0.002	0.998
I00 Rheumatic fever without mention of heart involvement	0.002	0.998
I09 Other rheumatic heart diseases	0.002	0.998
I08 Multiple valve diseases	0.002	0.998
I07 Rheumatic tricuspid valve diseases	0.002	0.998

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations