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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs192549394
log Bayes Factor = 1.61666
Chromosome 14   position 52,293,779  (GRCh37) Explore rs192549394 on Ensembl!
Variant rs192549394 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.975 0.025 0.000
Chapter IX Diseases of the circulatory system
0.967 0.033 0.000
Chapter VII Diseases of the eye and adnexa
0.966 0.034 0.000
Chapter II Neoplasms
0.956 0.044 0.000
I30-I52 Other forms of heart disease
0.940 0.060 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.934 0.066 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.931 0.069 0.000
H30-H36 Disorders of choroid and retina
0.930 0.070 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.921 0.079 0.000
H33 Retinal detachments and breaks
0.897 0.103 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.896 0.104 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.895 0.105 0.000
I51 Complications and ill-defined descriptions of heart disease
0.894 0.106 0.000
I50 Heart failure
0.889 0.111 0.000
C79 Secondary malignant neoplasm of other sites
0.885 0.115 0.000
Chapter V Mental and behavioural disorders
0.874 0.126 0.000
O60-O75 Complications of labour and delivery
0.869 0.131 0.000
I78 Diseases of capillaries
0.856 0.144 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.853 0.147 0.000
D60-D64 Aplastic and other anaemias
0.852 0.148 0.000
I77 Other disorders of arteries and arterioles
0.851 0.149 0.000
H33.2 Serous retinal detachment
0.847 0.153 0.000
C15-C26 Malignant neoplasms of digestive organs
0.847 0.153 0.000
I51.7 Cardiomegaly
0.846 0.154 0.000
Chapter VIII Diseases of the ear and mastoid process
0.845 0.155 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.845 0.155 0.000
I34 Nonrheumatic mitral valve disorders
0.831 0.169 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.829 0.171 0.000
H53-H54 Visual disturbances and blindness
0.826 0.174 0.000
Chapter X Diseases of the respiratory system
0.815 0.185 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.814 0.185 0.000
H43-H45 Disorders of vitreous body and globe
0.806 0.194 0.000
I20-I25 Ischaemic heart diseases
0.805 0.195 0.000
H10-H13 Disorders of conjunctiva
0.802 0.197 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.802 0.198 0.000
C50-C50 Malignant neoplasm of breast
0.794 0.206 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.792 0.208 0.000
I50.1 Left ventricular failure
0.791 0.209 0.000
H33.3 Retinal breaks without detachment
0.778 0.222 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
I34.0 Mitral (valve) insufficiency
0.776 0.224 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.772 0.228 0.000
I73 Other peripheral vascular diseases
0.768 0.232 0.000
C64-C68 Malignant neoplasms of urinary tract
0.765 0.235 0.000
D00-D09 In situ neoplasms
0.762 0.238 0.000
I95 Hypotension
0.761 0.239 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.759 0.241 0.000
I78.1 Naevus, nonneoplastic
0.759 0.241 0.000
I77.6 Arteritis, unspecified
0.758 0.242 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.756 0.243 0.000
I50.9 Heart failure, unspecified
0.756 0.244 0.000
J40-J47 Chronic lower respiratory diseases
0.756 0.244 0.000
O00-O08 Pregnancy with abortive outcome
0.753 0.247 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.753 0.247 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.750 0.250 0.000
F20 Schizophrenia
0.747 0.253 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.745 0.255 0.000
H65-H75 Diseases of middle ear and mastoid
0.745 0.255 0.000
H35 Other retinal disorders
0.741 0.259 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.736 0.264 0.000
C18 Malignant neoplasm of colon
0.736 0.264 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.735 0.265 0.000
D64 Other anaemias
0.734 0.266 0.000
I33 Acute and subacute endocarditis
0.734 0.266 0.000
S10-S19 Injuries to the neck
0.730 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.729 0.271 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.727 0.273 0.000
S80-S89 Injuries to the knee and lower leg
0.725 0.275 0.000
H90-H95 Other disorders of ear
0.725 0.275 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.723 0.277 0.000
H34 Retinal vascular occlusions
0.723 0.277 0.000
M70-M79 Other soft tissue disorders
0.720 0.280 0.000
D50-D53 Nutritional anaemias
0.720 0.280 0.000
H54 Blindness and low vision
0.720 0.280 0.000
I38 Endocarditis, valve unspecified
0.719 0.281 0.000
C79.2 Secondary malignant neoplasm of skin
0.719 0.281 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.718 0.282 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.716 0.283 0.000
I42 Cardiomyopathy
0.716 0.284 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
O73 Retained placenta and membranes, without haemorrhage
0.714 0.286 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.713 0.286 0.000
C34 Malignant neoplasm of bronchus and lung
0.713 0.287 0.000
C15 Malignant neoplasm of oesophagus
0.712 0.288 0.000
I50.0 Congestive heart failure
0.712 0.288 0.000
D61 Other aplastic anaemias
0.712 0.288 0.000
I51.8 Other ill-defined heart diseases
0.708 0.292 0.000
S00-S09 Injuries to the head
0.706 0.294 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.699 0.301 0.000
S60-S69 Injuries to the wrist and hand
0.698 0.302 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.698 0.302 0.000
I74 Arterial embolism and thrombosis
0.697 0.303 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.697 0.303 0.000
S40-S49 Injuries to the shoulder and upper arm
0.695 0.305 0.000
I00-I02 Acute rheumatic fever
0.693 0.307 0.000
H43 Disorders of vitreous body
0.691 0.309 0.000
I46 Cardiac arrest
0.687 0.312 0.000
I73.9 Peripheral vascular disease, unspecified
0.687 0.313 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.686 0.314 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.685 0.315 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.685 0.315 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.685 0.315 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.685 0.315 0.000
M75 Shoulder lesions
0.684 0.316 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.684 0.316 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.683 0.317 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.683 0.317 0.000
O70 Perineal laceration during delivery
0.681 0.319 0.000
O04 Medical abortion
0.680 0.319 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.681 0.319 0.000
I77.8 Other specified disorders of arteries and arterioles
0.679 0.321 0.000
I21 Acute myocardial infarction
0.679 0.321 0.000
S70-S79 Injuries to the hip and thigh
0.679 0.321 0.000
J47 Bronchiectasis
0.679 0.321 0.000
C50 Malignant neoplasm of breast
0.678 0.322 0.000
F29 Unspecified nonorganic psychosis
0.676 0.324 0.000
D80-D89 Certain disorders involving the immune mechanism
0.674 0.326 0.000
I52 Other heart disorders in diseases classified elsewhere
0.674 0.326 0.000
I48 Atrial fibrillation and flutter
0.674 0.326 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.674 0.326 0.000
I41 Myocarditis in diseases classified elsewhere
0.674 0.326 0.000
I40 Acute myocarditis
0.674 0.326 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.674 0.326 0.000
I37 Pulmonary valve disorders
0.674 0.326 0.000
I36 Nonrheumatic tricuspid valve disorders
0.674 0.326 0.000
I32 Pericarditis in diseases classified elsewhere
0.674 0.326 0.000
I30 Acute pericarditis
0.674 0.326 0.000
J09-J18 Influenza and pneumonia
0.673 0.327 0.000
C25 Malignant neoplasm of pancreas
0.671 0.329 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.670 0.330 0.000
I72 Other aneurysm
0.670 0.330 0.000
I70 Atherosclerosis
0.670 0.330 0.000
O85-O92 Complications predominantly related to the puerperium
0.667 0.333 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.667 0.333 0.000
H31 Other disorders of choroid
0.667 0.333 0.000
H30 Chorioretinal inflammation
0.667 0.333 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.665 0.335 0.000
I51.9 Heart disease, unspecified
0.665 0.335 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.664 0.336 0.000
C18.2 Ascending colon
0.664 0.336 0.000
D62 Acute posthaemorrhagic anaemia
0.662 0.338 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.661 0.339 0.000
I23 Certain current complications following acute myocardial infarction
0.661 0.339 0.000
D55-D59 Haemolytic anaemias
0.661 0.339 0.000
J95-J99 Other diseases of the respiratory system
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
F25 Schizoaffective disorders
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.656 0.344 0.000
D03 Melanoma in situ
0.654 0.346 0.000
C80 Malignant neoplasm without specification of site
0.653 0.347 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.652 0.347 0.000
H52 Disorders of refraction and accommodation
0.651 0.349 0.000
D64.9 Anaemia, unspecified
0.650 0.350 0.000
H73 Other disorders of tympanic membrane
0.649 0.351 0.000
O43 Placental disorders
0.649 0.351 0.000
M75.1 Rotator cuff syndrome
0.648 0.352 0.000
F20.0 Paranoid schizophrenia
0.647 0.353 0.000
H11 Other disorders of conjunctiva
0.647 0.353 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.645 0.355 0.000
H33.5 Other retinal detachments
0.643 0.357 0.000
H33.4 Traction detachment of retina
0.643 0.357 0.000
H33.1 Retinoschisis and retinal cysts
0.643 0.357 0.000
T33-T35 Frostbite
0.642 0.358 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.642 0.358 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.642 0.358 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.642 0.358 0.000
T00-T07 Injuries involving multiple body regions
0.642 0.358 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.642 0.358 0.000
I51.6 Cardiovascular disease, unspecified
0.641 0.359 0.000
I51.5 Myocardial degeneration
0.641 0.359 0.000
I51.4 Myocarditis, unspecified
0.641 0.359 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.641 0.359 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.641 0.359 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.641 0.359 0.000
I51.0 Cardiac septal defect, acquired
0.641 0.359 0.000
T79-T79 Certain early complications of trauma
0.640 0.359 0.000
E70-E90 Metabolic disorders
0.639 0.361 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.638 0.362 0.000
D69 Purpura and other haemorrhagic conditions
0.638 0.362 0.000
I77.1 Stricture of artery
0.638 0.362 0.000
H33.0 Retinal detachment with retinal break
0.637 0.363 0.000
F22 Persistent delusional disorders
0.635 0.365 0.000
J46 Status asthmaticus
0.635 0.365 0.000
I95.1 Orthostatic hypotension
0.634 0.365 0.000
C79.6 Secondary malignant neoplasm of ovary
0.634 0.366 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.634 0.366 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.634 0.366 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.634 0.366 0.000
M72 Fibroblastic disorders
0.633 0.367 0.000
S90-S99 Injuries to the ankle and foot
0.632 0.368 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.632 0.368 0.000
H10 Conjunctivitis
0.631 0.369 0.000
O04.9 Complete or unspecified, without complication
0.629 0.371 0.000
O41 Other disorders of amniotic fluid and membranes
0.628 0.372 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.627 0.373 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.627 0.373 0.000
I27 Other pulmonary heart diseases
0.627 0.373 0.000
F99-F99 Unspecified mental disorder
0.627 0.373 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.627 0.373 0.000
F80-F89 Disorders of psychological development
0.627 0.373 0.000
F70-F79 Mental retardation
0.627 0.373 0.000
F60-F69 Disorders of adult personality and behaviour
0.627 0.373 0.000
H40-H42 Glaucoma
0.624 0.376 0.000
O74 Complications of anaesthesia during labour and delivery
0.623 0.377 0.000
O71 Other obstetric trauma
0.623 0.377 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.623 0.377 0.000
O66 Other obstructed labour
0.623 0.377 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.623 0.377 0.000
O62 Abnormalities of forces of labour
0.623 0.377 0.000
O61 Failed induction of labour
0.623 0.377 0.000
O60 Preterm delivery
0.623 0.377 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.622 0.378 0.000
F20.9 Schizophrenia, unspecified
0.622 0.378 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.622 0.378 0.000
S32 Fracture of lumbar spine and pelvis
0.621 0.378 0.000
C67 Malignant neoplasm of bladder
0.621 0.379 0.000
J42 Unspecified chronic bronchitis
0.620 0.380 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.618 0.382 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.615 0.385 0.000
H91 Other hearing loss
0.615 0.385 0.000
I78.9 Disease of capillaries, unspecified
0.614 0.386 0.000
I78.8 Other diseases of capillaries
0.614 0.386 0.000
I45 Other conduction disorders
0.613 0.386 0.000
I95.2 Hypotension due to drugs
0.613 0.387 0.000
C34.9 Bronchus or lung, unspecified
0.612 0.388 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.611 0.388 0.000
I99 Other and unspecified disorders of circulatory system
0.611 0.388 0.000
D61.9 Aplastic anaemia, unspecified
0.611 0.389 0.000
O80-O84 Delivery
0.611 0.389 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.611 0.389 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.610 0.389 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.610 0.390 0.000
I77.5 Necrosis of artery
0.610 0.390 0.000
I77.4 Coeliac artery compression syndrome
0.610 0.390 0.000
I77.3 Arterial fibromuscular dysplasia
0.610 0.390 0.000
I77.2 Rupture of artery
0.610 0.390 0.000
I77.0 Arteriovenous fistula, acquired
0.610 0.390 0.000
I22 Subsequent myocardial infarction
0.609 0.391 0.000
I24 Other acute ischaemic heart diseases
0.608 0.392 0.000
O48 Prolonged pregnancy
0.608 0.392 0.000
M80-M85 Disorders of bone density and structure
0.607 0.393 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.607 0.393 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.607 0.393 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.607 0.393 0.000
C21 Malignant neoplasm of anus and anal canal
0.607 0.393 0.000
C17 Malignant neoplasm of small intestine
0.607 0.393 0.000
C16 Malignant neoplasm of stomach
0.607 0.393 0.000
C23 Malignant neoplasm of gallbladder
0.607 0.393 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.607 0.393 0.000
H18 Other disorders of cornea
0.606 0.394 0.000
J40 Bronchitis, not specified as acute or chronic
0.606 0.394 0.000
S80 Superficial injury of lower leg
0.606 0.394 0.000
H53 Visual disturbances
0.604 0.396 0.000
O72 Postpartum haemorrhage
0.603 0.397 0.000
O73.0 Retained placenta, without haemorrhage
0.602 0.397 0.000
D68 Other coagulation defects
0.600 0.400 0.000
I95.9 Hypotension, unspecified
0.598 0.402 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.597 0.403 0.000
I31 Other diseases of pericardium
0.597 0.403 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.595 0.404 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.595 0.404 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.595 0.404 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.595 0.405 0.000
F23 Acute and transient psychotic disorders
0.594 0.406 0.000
F28 Other nonorganic psychotic disorders
0.594 0.406 0.000
F24 Induced delusional disorder
0.594 0.406 0.000
F21 Schizotypal disorder
0.594 0.406 0.000
O63 Long labour
0.594 0.406 0.000
H50 Other strabismus
0.593 0.407 0.000
H35.8 Other specified retinal disorders
0.593 0.407 0.000
E50-E64 Other nutritional deficiencies
0.592 0.408 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.592 0.408 0.000
C18.4 Transverse colon
0.590 0.410 0.000
S20-S29 Injuries to the thorax
0.589 0.411 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.588 0.412 0.000
H46 Optic neuritis
0.587 0.413 0.000
I33.0 Acute and subacute infective endocarditis
0.587 0.413 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.587 0.413 0.000
O20 Haemorrhage in early pregnancy
0.586 0.413 0.000
H43.3 Other vitreous opacities
0.586 0.414 0.000
H25-H28 Disorders of lens
0.586 0.414 0.000
H74 Other disorders of middle ear and mastoid
0.585 0.415 0.000
O00 Ectopic pregnancy
0.584 0.416 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.584 0.416 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.584 0.416 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.584 0.416 0.000
C32 Malignant neoplasm of larynx
0.584 0.416 0.000
C31 Malignant neoplasm of accessory sinuses
0.584 0.416 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.584 0.416 0.000
C37 Malignant neoplasm of thymus
0.584 0.416 0.000
C33 Malignant neoplasm of trachea
0.584 0.416 0.000
D51 Vitamin B12 deficiency anaemia
0.584 0.416 0.000
I21.9 Acute myocardial infarction, unspecified
0.581 0.419 0.000
H73.8 Other specified disorders of tympanic membrane
0.580 0.420 0.000
C50.4 Upper-outer quadrant of breast
0.580 0.420 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.580 0.420 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.579 0.421 0.000
O21 Excessive vomiting in pregnancy
0.579 0.421 0.000
S01 Open wound of head
0.578 0.421 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.578 0.422 0.000
M77 Other enthesopathies
0.578 0.422 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.578 0.422 0.000
H44 Disorders of globe
0.578 0.422 0.000
H71 Cholesteatoma of middle ear
0.577 0.423 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.577 0.423 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.577 0.423 0.000
O36 Maternal care for other known or suspected foetal problems
0.577 0.423 0.000
D04 Carcinoma in situ of skin
0.576 0.424 0.000
J00-J06 Acute upper respiratory infections
0.576 0.424 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.575 0.424 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.575 0.425 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.575 0.425 0.000
E83 Disorders of mineral metabolism
0.575 0.425 0.000
H34.8 Other retinal vascular occlusions
0.575 0.425 0.000
O45 Premature separation of placenta [abruptio placentae]
0.575 0.425 0.000
O44 Placenta praevia
0.575 0.425 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.575 0.425 0.000
O33 Maternal care for known or suspected disproportion
0.575 0.425 0.000
O31 Complications specific to multiple gestation
0.575 0.425 0.000
O40 Polyhydramnios
0.575 0.425 0.000
H54.9 Unspecified visual impairment (binocular)
0.574 0.426 0.000
J30-J39 Other diseases of upper respiratory tract
0.574 0.426 0.000
C15.9 Oesophagus, unspecified
0.574 0.426 0.000
H60-H62 Diseases of external ear
0.573 0.427 0.000
C15.5 Lower third of oesophagus
0.572 0.428 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.571 0.429 0.000
O30 Multiple gestation
0.570 0.430 0.000
H36 Retinal disorders in diseases classified elsewhere
0.569 0.430 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.569 0.430 0.000
Q50-Q56 Congenital malformations of genital organs
0.568 0.431 0.000
H51 Other disorders of binocular movement
0.568 0.432 0.000
H49 Paralytic strabismus
0.568 0.432 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.568 0.432 0.000
S50-S59 Injuries to the elbow and forearm
0.567 0.433 0.000
T78 Adverse effects, not elsewhere classified
0.567 0.433 0.000
Chapter VI Diseases of the nervous system
0.566 0.433 0.000
O42 Premature rupture of membranes
0.566 0.434 0.000
S67 Crushing injury of wrist and hand
0.564 0.436 0.000
C73 Malignant neoplasm of thyroid gland
0.563 0.437 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.562 0.437 0.000
C50.9 Breast, unspecified
0.562 0.438 0.000
H54.7 Unspecified visual loss
0.561 0.439 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.561 0.439 0.000
H90 Conductive and sensorineural hearing loss
0.559 0.441 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.559 0.441 0.000
D52 Folate deficiency anaemia
0.559 0.441 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.558 0.442 0.000
C34.1 Upper lobe, bronchus or lung
0.558 0.442 0.000
I23.8 Other current complications following acute myocardial infarction
0.558 0.442 0.000
O47 False labour
0.557 0.443 0.000
H57 Other disorders of eye and adnexa
0.557 0.443 0.000
E20-E35 Disorders of other endocrine glands
0.557 0.443 0.000
C54 Malignant neoplasm of corpus uteri
0.556 0.444 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.555 0.445 0.000
J98 Other respiratory disorders
0.555 0.445 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.555 0.445 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.555 0.445 0.000
S81 Open wound of lower leg
0.554 0.446 0.000
D67 Hereditary factor IX deficiency
0.554 0.446 0.000
D66 Hereditary factor VIII deficiency
0.554 0.446 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.554 0.446 0.000
H55 Nystagmus and other irregular eye movements
0.554 0.446 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.553 0.447 0.000
Q80-Q89 Other congenital malformations
0.553 0.447 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.553 0.447 0.000
Q60-Q64 Congenital malformations of the urinary system
0.553 0.447 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.553 0.447 0.000
Q35-Q37 Cleft lip and cleft palate
0.553 0.447 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.553 0.447 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.553 0.447 0.000
Q00-Q07 Congenital malformations of the nervous system
0.553 0.447 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.553 0.447 0.000
H54.0 Blindness, both eyes
0.553 0.447 0.000
H54.4 Blindness, one eye
0.552 0.448 0.000
S42 Fracture of shoulder and upper arm
0.551 0.449 0.000
I73.8 Other specified peripheral vascular diseases
0.550 0.449 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.550 0.449 0.000
I42.9 Cardiomyopathy, unspecified
0.549 0.450 0.000
S32.5 Fracture of pubis
0.549 0.451 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.549 0.451 0.000
C66 Malignant neoplasm of ureter
0.549 0.451 0.000
C65 Malignant neoplasm of renal pelvis
0.549 0.451 0.000
C92 Myeloid leukaemia
0.548 0.452 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.548 0.452 0.000
H35.3 Degeneration of macula and posterior pole
0.548 0.452 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.547 0.452 0.000
F43 Reaction to severe stress, and adjustment disorders
0.547 0.453 0.000
I05-I09 Chronic rheumatic heart diseases
0.546 0.453 0.000
D09 Carcinoma in situ of other and unspecified sites
0.546 0.454 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.546 0.454 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.546 0.454 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.546 0.454 0.000
J60-J70 Lung diseases due to external agents
0.546 0.454 0.000
I95.8 Other hypotension
0.546 0.454 0.000
I95.0 Idiopathic hypotension
0.546 0.454 0.000
S06 Intracranial injury
0.545 0.455 0.000
H92 Otalgia and effusion of ear
0.545 0.455 0.000
O70.9 Perineal laceration during delivery, unspecified
0.545 0.455 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.544 0.455 0.000
E83.5 Disorders of calcium metabolism
0.543 0.457 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.542 0.457 0.000
H21 Other disorders of iris and ciliary body
0.542 0.457 0.000
H20 Iridocyclitis
0.542 0.457 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.542 0.457 0.000
H17 Corneal scars and opacities
0.542 0.457 0.000
H16 Keratitis
0.542 0.457 0.000
H15 Disorders of sclera
0.542 0.457 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.542 0.458 0.000
J41 Simple and mucopurulent chronic bronchitis
0.542 0.458 0.000
C81 Hodgkin's disease
0.541 0.459 0.000
D46 Myelodysplastic syndromes
0.540 0.459 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.540 0.460 0.000
O07 Failed attempted abortion
0.540 0.460 0.000
O06 Unspecified abortion
0.540 0.460 0.000
O05 Other abortion
0.540 0.460 0.000
O01 Hydatidiform mole
0.540 0.460 0.000
I28 Other diseases of pulmonary vessels
0.540 0.460 0.000
O43.1 Malformation of placenta
0.539 0.461 0.000
M86-M90 Other osteopathies
0.538 0.461 0.000
M71 Other bursopathies
0.538 0.462 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.537 0.462 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.537 0.462 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.537 0.462 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.537 0.462 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.537 0.462 0.000
M75.3 Calcific tendinitis of shoulder
0.536 0.464 0.000
I35 Nonrheumatic aortic valve disorders
0.536 0.464 0.000
H91.9 Hearing loss, unspecified
0.536 0.464 0.000
F20.8 Other schizophrenia
0.535 0.465 0.000
F20.6 Simple schizophrenia
0.535 0.465 0.000
F20.5 Residual schizophrenia
0.535 0.465 0.000
F20.4 Postschizophrenic depression
0.535 0.465 0.000
F20.3 Undifferentiated schizophrenia
0.535 0.465 0.000
F20.2 Catatonic schizophrenia
0.535 0.465 0.000
F20.1 Hebephrenic schizophrenia
0.535 0.465 0.000
H52.1 Myopia
0.535 0.465 0.000
C20 Malignant neoplasm of rectum
0.535 0.465 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.534 0.465 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.534 0.465 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.534 0.466 0.000
H70 Mastoiditis and related conditions
0.534 0.466 0.000
H69 Other disorders of Eustachian tube
0.534 0.466 0.000
H68 Eustachian salpingitis and obstruction
0.534 0.466 0.000
H67 Otitis media in diseases classified elsewhere
0.534 0.466 0.000
M75.2 Bicipital tendinitis
0.533 0.467 0.000
I27.2 Other secondary pulmonary hypertension
0.533 0.467 0.000
F25.9 Schizoaffective disorder, unspecified
0.533 0.467 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.532 0.468 0.000
J44 Other chronic obstructive pulmonary disease
0.532 0.468 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.531 0.469 0.000
H35.9 Retinal disorder, unspecified
0.531 0.469 0.000
H35.7 Separation of retinal layers
0.531 0.469 0.000
H35.6 Retinal haemorrhage
0.531 0.469 0.000
H35.5 Hereditary retinal dystrophy
0.531 0.469 0.000
H35.4 Peripheral retinal degeneration
0.531 0.469 0.000
H35.2 Other proliferative retinopathy
0.531 0.469 0.000
H35.1 Retinopathy of prematurity
0.531 0.469 0.000
H35.0 Background retinopathy and retinal vascular changes
0.531 0.469 0.000
S89 Other and unspecified injuries of lower leg
0.530 0.470 0.000
C18.7 Sigmoid colon
0.530 0.470 0.000
H72 Perforation of tympanic membrane
0.529 0.471 0.000
M91-M94 Chondropathies
0.528 0.472 0.000
M60-M63 Disorders of muscles
0.528 0.472 0.000
M00-M03 Infectious arthropathies
0.528 0.472 0.000
C18.8 Overlapping lesion of colon
0.528 0.472 0.000
C18.6 Descending colon
0.528 0.472 0.000
C18.5 Splenic flexure
0.528 0.472 0.000
C18.3 Hepatic flexure
0.528 0.472 0.000
C18.1 Appendix
0.528 0.472 0.000
F52.2 Failure of genital response
0.527 0.473 0.000
O29 Complications of anaesthesia during pregnancy
0.527 0.473 0.000
O28 Abnormal findings on antenatal screening of mother
0.527 0.473 0.000
O24 Diabetes mellitus in pregnancy
0.527 0.473 0.000
O23 Infections of genito-urinary tract in pregnancy
0.527 0.473 0.000
O22 Venous complications in pregnancy
0.527 0.473 0.000
O25 Malnutrition in pregnancy
0.527 0.473 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.527 0.473 0.000
D64.8 Other specified anaemias
0.527 0.473 0.000
D64.4 Congenital dyserythropoietic anaemia
0.527 0.473 0.000
D64.3 Other sideroblastic anaemias
0.527 0.473 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.527 0.473 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.527 0.473 0.000
D64.0 Hereditary sideroblastic anaemia
0.527 0.473 0.000
I33.9 Acute endocarditis, unspecified
0.526 0.474 0.000
C34.3 Lower lobe, bronchus or lung
0.526 0.474 0.000
H43.8 Other disorders of vitreous body
0.525 0.475 0.000
S13.4 Sprain and strain of cervical spine
0.525 0.475 0.000
T92 Sequelae of injuries of upper limb
0.524 0.476 0.000
J43 Emphysema
0.524 0.476 0.000
D69.5 Secondary thrombocytopenia
0.524 0.476 0.000
D06 Carcinoma in situ of cervix uteri
0.524 0.476 0.000
S19 Other and unspecified injuries of neck
0.523 0.477 0.000
S17 Crushing injury of neck
0.523 0.477 0.000
S15 Injury of blood vessels at neck level
0.523 0.477 0.000
S14 Injury of nerves and spinal cord at neck level
0.523 0.477 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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