TreeWAS – Variant ID: rs193141495

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.985	0.015
Chapter IX Diseases of the circulatory system	0.977	0.023
Chapter XXI Factors influencing health status and contact with health services	0.975	0.025
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.972	0.028
I20-I25 Ischaemic heart diseases	0.965	0.035
Z95 Presence of cardiac and vascular implants and grafts	0.946	0.054
Chapter XIV Diseases of the genitourinary system	0.940	0.060
I25 Chronic ischaemic heart disease	0.940	0.060
Chapter VII Diseases of the eye and adnexa	0.912	0.088
Z92 Personal history of medical treatment	0.901	0.099
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.894	0.106
Z95.0 Presence of cardiac pacemaker	0.886	0.114
I25.2 Old myocardial infarction	0.883	0.117
N80-N98 Noninflammatory disorders of female genital tract	0.880	0.120
Chapter II Neoplasms	0.879	0.121
I30-I52 Other forms of heart disease	0.878	0.122
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.859	0.141
Z86 Personal history of certain other diseases	0.857	0.143
Z92.1 Personal history of long-term (current) use of anticoagulants	0.853	0.147
Z95.1 Presence of aortocoronary bypass graft	0.849	0.151
Chapter IV Endocrine, nutritional and metabolic diseases	0.847	0.153
H25-H28 Disorders of lens	0.834	0.166
I21 Acute myocardial infarction	0.832	0.168
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.820	0.180
I25.9 Chronic ischaemic heart disease, unspecified	0.815	0.185
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.809	0.191
Z91 Personal history of risk-factors, not elsewhere classified	0.808	0.192
N17-N19 Renal failure	0.806	0.194
Z87 Personal history of other diseases and conditions	0.804	0.195
T36-T50 Poisoning by drugs, medicaments and biological substances	0.802	0.198
Z86.7 Personal history of diseases of the circulatory system	0.795	0.205
Z95.2 Presence of prosthetic heart valve	0.780	0.220
C43-C44 Melanoma and other malignant neoplasms of skin	0.779	0.221
Chapter XV Pregnancy, childbirth and the puerperium	0.778	0.222
I24 Other acute ischaemic heart diseases	0.777	0.223
H25 Senile cataract	0.772	0.228
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.762	0.238
R10 Abdominal and pelvic pain	0.749	0.251
D10-D36 Benign neoplasms	0.747	0.253
N85 Other noninflammatory disorders of uterus, except cervix	0.737	0.263
N92 Excessive, frequent and irregular menstruation	0.735	0.265
I25.8 Other forms of chronic ischaemic heart disease	0.731	0.269
I10-I15 Hypertensive diseases	0.729	0.271
Z87.4 Personal history of diseases of the genito-urinary system	0.726	0.274
R13 Dysphagia	0.725	0.275
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.722	0.278
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.720	0.280
I51 Complications and ill-defined descriptions of heart disease	0.714	0.286
I34 Nonrheumatic mitral valve disorders	0.714	0.286
R14 Flatulence and related conditions	0.713	0.287
I50 Heart failure	0.711	0.289
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.711	0.289
M05-M14 Inflammatory polyarthropathies	0.710	0.290
Z96 Presence of other functional implants	0.709	0.291
I20 Angina pectoris	0.709	0.291
I25.1 Atherosclerotic heart disease	0.708	0.292
C44 Other malignant neoplasms of skin	0.707	0.293
E00-E07 Disorders of thyroid gland	0.706	0.294
Chapter XXII Codes for special purposes	0.706	0.294
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.706	0.294
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.294
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.705	0.295
Chapter VIII Diseases of the ear and mastoid process	0.704	0.296
I60-I69 Cerebrovascular diseases	0.703	0.297
N25-N29 Other disorders of kidney and ureter	0.703	0.297
N20-N23 Urolithiasis	0.701	0.299
I05-I09 Chronic rheumatic heart diseases	0.700	0.300
I00-I02 Acute rheumatic fever	0.700	0.300
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.699	0.301
N88 Other noninflammatory disorders of cervix uteri	0.697	0.303
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.697	0.303
Z98 Other postsurgical states	0.697	0.303
Z97 Presence of other devices	0.697	0.303
Z94 Transplanted organ and tissue status	0.697	0.303
Z93 Artificial opening status	0.697	0.303
Z89 Acquired absence of limb	0.697	0.303
Z84 Family history of other conditions	0.697	0.303
Z83 Family history of other specific disorders	0.697	0.303
Z81 Family history of mental and behavioural disorders	0.697	0.303
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.693	0.307
I23 Certain current complications following acute myocardial infarction	0.692	0.308
I22 Subsequent myocardial infarction	0.692	0.308
H25.1 Senile nuclear cataract	0.691	0.309
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.691	0.309
N40-N51 Diseases of male genital organs	0.690	0.310
I95-I99 Other and unspecified disorders of the circulatory system	0.689	0.311
H40-H42 Glaucoma	0.688	0.312
H30-H36 Disorders of choroid and retina	0.686	0.314
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.682	0.318
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.678	0.322
Z95.8 Presence of other cardiac and vascular implants and grafts	0.678	0.322
Z95.4 Presence of other heart-valve replacement	0.678	0.322
Z95.3 Presence of xenogenic heart valve	0.678	0.322
N99-N99 Other disorders of the genitourinary system	0.674	0.326
N60-N64 Disorders of breast	0.674	0.326
N10-N16 Renal tubulo-interstitial diseases	0.674	0.326
N00-N08 Glomerular diseases	0.674	0.326
I25.6 Silent myocardial ischaemia	0.674	0.326
I25.5 Ischaemic cardiomyopathy	0.674	0.326
I25.4 Coronary artery aneurysm	0.674	0.326
I25.3 Aneurysm of heart	0.674	0.326
I25.0 Atherosclerotic cardiovascular disease, so described	0.674	0.326
I21.0 Acute transmural myocardial infarction of anterior wall	0.669	0.331
Z91.5 Personal history of self-harm	0.667	0.333
C64-C68 Malignant neoplasms of urinary tract	0.666	0.334
S00-S09 Injuries to the head	0.666	0.334
Z90 Acquired absence of organs, not elsewhere classified	0.666	0.334
E10-E14 Diabetes mellitus	0.666	0.334
N18 Chronic renal failure	0.665	0.335
D27 Benign neoplasm of ovary	0.664	0.336
Z70-Z76 Persons encountering health services in other circumstances	0.664	0.336
S80-S89 Injuries to the knee and lower leg	0.660	0.340
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.659	0.341
I70-I79 Diseases of arteries, arterioles and capillaries	0.658	0.342
R10.3 Pain localised to other parts of lower abdomen	0.658	0.342
I21.9 Acute myocardial infarction, unspecified	0.655	0.345
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.655	0.345
E70-E90 Metabolic disorders	0.654	0.346
H55-H59 Other disorders of eye and adnexa	0.654	0.346
H53-H54 Visual disturbances and blindness	0.654	0.346
H46-H48 Disorders of optic nerve and visual pathways	0.654	0.346
H43-H45 Disorders of vitreous body and globe	0.654	0.346
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.654	0.346
H10-H13 Disorders of conjunctiva	0.654	0.346
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.654	0.346
Chapter V Mental and behavioural disorders	0.653	0.347
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.651	0.349
I21.1 Acute transmural myocardial infarction of inferior wall	0.649	0.351
C15-C26 Malignant neoplasms of digestive organs	0.647	0.352
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.647	0.353
Z00-Z13 Persons encountering health services for examination and investigation	0.647	0.353
N17 Acute renal failure	0.647	0.353
R47-R49 Symptoms and signs involving speech and voice	0.647	0.353
Z92.9 Personal history of medical treatment, unspecified	0.646	0.354
Z92.8 Personal history of other medical treatment	0.646	0.354
Z92.6 Personal history of chemotherapy for neoplastic disease	0.646	0.354
Z92.5 Personal history of rehabilitation measures	0.646	0.354
Z92.4 Personal history of major surgery, not elsewhere classified	0.646	0.354
Z92.3 Personal history of irradiation	0.646	0.354
Z92.0 Personal history of contraception	0.646	0.354
N85.2 Hypertrophy of uterus	0.645	0.355
I24.9 Acute ischaemic heart disease, unspecified	0.642	0.358
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.641	0.359
T79-T79 Certain early complications of trauma	0.641	0.359
T66-T78 Other and unspecified effects of external causes	0.641	0.359
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.641	0.359
T33-T35 Frostbite	0.641	0.359
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.641	0.359
T26-T28 Burns and corrosions confined to eye and internal organs	0.641	0.359
T20-T25 Burns and corrosions of external body surface, specified by site	0.641	0.359
T15-T19 Effects of foreign body entering through natural orifice	0.641	0.359
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.641	0.359
T00-T07 Injuries involving multiple body regions	0.641	0.359
S90-S99 Injuries to the ankle and foot	0.641	0.359
S70-S79 Injuries to the hip and thigh	0.641	0.359
S60-S69 Injuries to the wrist and hand	0.641	0.359
S40-S49 Injuries to the shoulder and upper arm	0.641	0.359
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.641	0.359
S20-S29 Injuries to the thorax	0.641	0.359
S10-S19 Injuries to the neck	0.641	0.359
N70-N77 Inflammatory diseases of female pelvic organs	0.641	0.359
M45-M49 Spondylopathies	0.640	0.360
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.639	0.361
Z92.2 Personal history of long-term (current) use of other medicaments	0.638	0.362
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.636	0.364
I47 Paroxysmal tachycardia	0.635	0.364
Z80 Family history of malignant neoplasm	0.635	0.365
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.634	0.366
R50-R69 General symptoms and signs	0.632	0.368
Chapter XX External causes of morbidity and mortality	0.631	0.369
N98 Complications associated with artificial fertilisation	0.631	0.369
N97 Female infertility	0.631	0.369
N93 Other abnormal uterine and vaginal bleeding	0.631	0.369
N91 Absent, scanty and rare menstruation	0.631	0.369
N90 Other noninflammatory disorders of vulva and perineum	0.631	0.369
N89 Other noninflammatory disorders of vagina	0.631	0.369
N87 Dysplasia of cervix uteri	0.631	0.369
N82 Fistulae involving female genital tract	0.631	0.369
N80 Endometriosis	0.631	0.369
N96 Habitual aborter	0.631	0.369
N86 Erosion and ectropion of cervix uteri	0.631	0.369
Chapter VI Diseases of the nervous system	0.631	0.369
D37-D48 Neoplasms of uncertain or unknown behaviour	0.631	0.369
D00-D09 In situ neoplasms	0.631	0.369
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.631	0.369
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.631	0.369
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.631	0.369
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.631	0.369
C51-C58 Malignant neoplasms of female genital organs	0.631	0.369
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.631	0.369
C40-C41 Malignant neoplasms of bone and articular cartilage	0.631	0.369
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.631	0.369
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.630	0.370
R10.4 Other and unspecified abdominal pain	0.630	0.370
M13 Other arthritis	0.630	0.370
N94.6 Dysmenorrhoea, unspecified	0.630	0.370
I52 Other heart disorders in diseases classified elsewhere	0.629	0.370
I49 Other cardiac arrhythmias	0.629	0.370
I48 Atrial fibrillation and flutter	0.629	0.370
I46 Cardiac arrest	0.629	0.370
I45 Other conduction disorders	0.629	0.370
I44 Atrioventricular and left bundle-branch block	0.629	0.370
I43 Cardiomyopathy in diseases classified elsewhere	0.629	0.370
I42 Cardiomyopathy	0.629	0.370
I41 Myocarditis in diseases classified elsewhere	0.629	0.370
I40 Acute myocarditis	0.629	0.370
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.629	0.370
I37 Pulmonary valve disorders	0.629	0.370
I36 Nonrheumatic tricuspid valve disorders	0.629	0.370
I35 Nonrheumatic aortic valve disorders	0.629	0.370
I33 Acute and subacute endocarditis	0.629	0.370
I32 Pericarditis in diseases classified elsewhere	0.629	0.370
I31 Other diseases of pericardium	0.629	0.370
I30 Acute pericarditis	0.629	0.370
I38 Endocarditis, valve unspecified	0.629	0.370
Chapter I Certain infectious and parasitic diseases	0.629	0.371
R18 Ascites	0.629	0.371
H26 Other cataract	0.626	0.374
S50-S59 Injuries to the elbow and forearm	0.625	0.375
N94.1 Dyspareunia	0.623	0.377
Z86.0 Personal history of other neoplasms	0.620	0.380
O60-O75 Complications of labour and delivery	0.620	0.380
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.616	0.384
Z86.4 Personal history of psychoactive substance abuse	0.616	0.384
R95-R99 Ill-defined and unknown causes of mortality	0.616	0.384
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.616	0.384
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.616	0.384
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.616	0.384
N50 Other disorders of male genital organs	0.615	0.385
R10.2 Pelvic and perineal pain	0.615	0.385
Z86.5 Personal history of other mental and behavioural disorders	0.615	0.385
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.615	0.385
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.615	0.385
Z86.1 Personal history of infectious and parasitic diseases	0.613	0.387
H25.8 Other senile cataract	0.612	0.388
N30-N39 Other diseases of urinary system	0.611	0.388
C44.3 Skin of other and unspecified parts of face	0.611	0.389
E50-E64 Other nutritional deficiencies	0.607	0.393
E40-E46 Malnutrition	0.607	0.393
E20-E35 Disorders of other endocrine glands	0.607	0.393
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.607	0.393
H25.0 Senile incipient cataract	0.606	0.394
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.603	0.397
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.603	0.397
Z85 Personal history of malignant neoplasm	0.601	0.399
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.598	0.402
H27 Other disorders of lens	0.598	0.402
Z96.1 Presence of intraocular lens	0.598	0.402
Chapter XII Diseases of the skin and subcutaneous tissue	0.597	0.403
I51.7 Cardiomegaly	0.597	0.403
M80-M85 Disorders of bone density and structure	0.597	0.403
I21.X Presumed acute myicardial infaction (unconfirmed)	0.597	0.403
I21.4 Acute subendocardial myocardial infarction	0.597	0.403
I21.3 Acute transmural myocardial infarction of unspecified site	0.597	0.403
I21.2 Acute transmural myocardial infarction of other sites	0.597	0.403
I34.0 Mitral (valve) insufficiency	0.596	0.404
N92.0 Excessive and frequent menstruation with regular cycle	0.594	0.406
N81 Female genital prolapse	0.593	0.407
E03 Other hypothyroidism	0.593	0.407
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.592	0.408
T39.1 4-Aminophenol derivatives	0.589	0.411
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.588	0.412
R17 Unspecified jaundice	0.588	0.412
R12 Heartburn	0.588	0.412
M50-M54 Other dorsopathies	0.587	0.413
C44.6 Skin of upper limb, including shoulder	0.586	0.413
N19 Unspecified renal failure	0.584	0.415
Chapter X Diseases of the respiratory system	0.583	0.416
R15 Faecal incontinence	0.583	0.417
N92.1 Excessive and frequent menstruation with irregular cycle	0.583	0.417
N95 Menopausal and other perimenopausal disorders	0.582	0.418
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.580	0.420
M91-M94 Chondropathies	0.580	0.420
M86-M90 Other osteopathies	0.580	0.420
M65-M68 Disorders of synovium and tendon	0.580	0.420
M60-M63 Disorders of muscles	0.580	0.420
M40-M43 Deforming dorsopathies	0.580	0.420
M00-M03 Infectious arthropathies	0.580	0.420
N84 Polyp of female genital tract	0.580	0.420
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.579	0.421
Z91.7 Personal history of female genital mutilation	0.579	0.421
Z91.6 Personal history of other physical trauma	0.579	0.421
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.579	0.421
Z91.3 Personal history of unhealthy sleep-wake schedule	0.579	0.421
Z91.2 Personal history of poor personal hygiene	0.579	0.421
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.579	0.421
C50-C50 Malignant neoplasm of breast	0.579	0.421
D25 Leiomyoma of uterus	0.578	0.422
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.578	0.422
Z87.8 Personal history of other specified conditions	0.577	0.423
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.577	0.423
Z87.6 Personal history of certain conditions arising in the perinatal period	0.577	0.423
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.577	0.423
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.577	0.423
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.577	0.423
Z87.0 Personal history of diseases of the respiratory system	0.577	0.423
R42 Dizziness and giddiness	0.577	0.423
Z95.5 Presence of coronary angioplasty implant and graft	0.576	0.424
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.575	0.425
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.575	0.425
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.575	0.425
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.575	0.425
T46 Poisoning by agents primarily affecting the cardiovascular system	0.575	0.425
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.575	0.425
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.575	0.425
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.575	0.425
T41 Poisoning by anaesthetics and therapeutic gases	0.575	0.425
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.575	0.425
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.575	0.425
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.575	0.425
T36 Poisoning by systemic antibiotics	0.575	0.425
M13.9 Arthritis, unspecified	0.573	0.427
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.571	0.429
E65-E68 Obesity and other hyperalimentation	0.568	0.432
Z90.5 Acquired absence of kidney	0.567	0.432
N88.8 Other specified noninflammatory disorders of cervix uteri	0.566	0.434
N18.9 Chronic renal failure, unspecified	0.566	0.434
C43 Malignant melanoma of skin	0.558	0.441
I12 Hypertensive renal disease	0.558	0.442
O94-O99 Other obstetric conditions, not elsewhere classified	0.558	0.442
O85-O92 Complications predominantly related to the puerperium	0.558	0.442
O80-O84 Delivery	0.558	0.442
O20-O29 Other maternal disorders predominantly related to pregnancy	0.558	0.442
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.558	0.442
O00-O08 Pregnancy with abortive outcome	0.558	0.442
I24.8 Other forms of acute ischaemic heart disease	0.557	0.443
I24.1 Dressler's syndrome	0.557	0.443
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.557	0.443
E87 Other disorders of fluid, electrolyte and acid-base balance	0.557	0.443
I50.1 Left ventricular failure	0.554	0.446
H25.9 Senile cataract, unspecified	0.553	0.447
H25.2 Senile cataract, morgagnian type	0.553	0.447
D24 Benign neoplasm of breast	0.553	0.447
D22 Melanocytic naevi	0.553	0.447
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.551	0.449
I20.0 Unstable angina	0.549	0.451
I50.0 Congestive heart failure	0.546	0.454
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.546	0.454
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.546	0.454
N94.5 Secondary dysmenorrhoea	0.546	0.454
N94.4 Primary dysmenorrhoea	0.546	0.454
N94.3 Premenstrual tension syndrome	0.546	0.454
N94.2 Vaginismus	0.546	0.454
N94.0 Mittelschmerz	0.546	0.454
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.542	0.458
Z60 Problems related to social environment	0.541	0.459
H80-H83 Diseases of inner ear	0.539	0.461
M70-M79 Other soft tissue disorders	0.538	0.461
R10.0 Acute abdomen	0.537	0.463
I26 Pulmonary embolism	0.536	0.463
D36 Benign neoplasm of other and unspecified sites	0.536	0.464
D35 Benign neoplasm of other and unspecified endocrine glands	0.536	0.464
D33 Benign neoplasm of brain and other parts of central nervous system	0.536	0.464
D32 Benign neoplasm of meninges	0.536	0.464
D31 Benign neoplasm of eye and adnexa	0.536	0.464
D30 Benign neoplasm of urinary organs	0.536	0.464
D29 Benign neoplasm of male genital organs	0.536	0.464
D28 Benign neoplasm of other and unspecified female genital organs	0.536	0.464
D26 Other benign neoplasms of uterus	0.536	0.464
D23 Other benign neoplasms of skin	0.536	0.464
D21 Other benign neoplasms of connective and other soft tissue	0.536	0.464
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.536	0.464
D19 Benign neoplasm of mesothelial tissue	0.536	0.464
D18 Haemangioma and lymphangioma, any site	0.536	0.464
D16 Benign neoplasm of bone and articular cartilage	0.536	0.464
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.536	0.464
D14 Benign neoplasm of middle ear and respiratory system	0.536	0.464
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.536	0.464
D11 Benign neoplasm of major salivary glands	0.536	0.464
D10 Benign neoplasm of mouth and pharynx	0.536	0.464
D34 Benign neoplasm of thyroid gland	0.536	0.464
N28 Other disorders of kidney and ureter, not elsewhere classified	0.533	0.467
N17.9 Acute renal failure, unspecified	0.532	0.468
Z86.6 Personal history of diseases of the nervous system and sense organs	0.532	0.468
M06 Other rheumatoid arthritis	0.530	0.470
C44.5 Skin of trunk	0.529	0.470
E05 Thyrotoxicosis [hyperthyroidism]	0.529	0.470
E14 Unspecified diabetes mellitus	0.529	0.471
Z30 Contraceptive management	0.529	0.471
N85.9 Noninflammatory disorder of uterus, unspecified	0.528	0.472
N85.7 Haematometra	0.528	0.472
N85.6 Intra-uterine synechiae	0.528	0.472
N85.5 Inversion of uterus	0.528	0.472
N85.4 Malposition of uterus	0.528	0.472
N85.3 Subinvolution of uterus	0.528	0.472
N85.1 Endometrial adenomatous hyperplasia	0.528	0.472
N85.0 Endometrial glandular hyperplasia	0.528	0.472
H40 Glaucoma	0.528	0.472
N92.6 Irregular menstruation, unspecified	0.527	0.473
N92.5 Other specified irregular menstruation	0.527	0.473
N92.4 Excessive bleeding in the premenopausal period	0.527	0.473
N92.3 Ovulation bleeding	0.527	0.473
N92.2 Excessive menstruation at puberty	0.527	0.473
R53 Malaise and fatigue	0.527	0.473
N50.8 Other specified disorders of male genital organs	0.525	0.475
I50.9 Heart failure, unspecified	0.525	0.475
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.525	0.475
N23 Unspecified renal colic	0.523	0.477
I15 Secondary hypertension	0.523	0.477
I13 Hypertensive heart and renal disease	0.523	0.477
I11 Hypertensive heart disease	0.523	0.477
M20-M25 Other joint disorders	0.522	0.478
T42.4 Benzodiazepines	0.521	0.479
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.519	0.481
H33 Retinal detachments and breaks	0.518	0.482
Z65 Problems related to other psychosocial circumstances	0.518	0.482
Z64 Problems related to certain psychosocial circumstances	0.518	0.482
Z63 Other problems related to primary support group, including family circumstances	0.518	0.482
Z62 Other problems related to upbringing	0.518	0.482
Z61 Problems related to negative life events in childhood	0.518	0.482
Z59 Problems related to housing and economic circumstances	0.518	0.482
Z58 Problems related to physical environment	0.518	0.482
Z57 Occupational exposure to risk-factors	0.518	0.482
Z56 Problems related to employment and unemployment	0.518	0.482
Z55 Problems related to education and literacy	0.518	0.482
H52 Disorders of refraction and accommodation	0.518	0.482
H26.4 After-cataract	0.517	0.483
M15-M19 Arthrosis	0.517	0.483
I28 Other diseases of pulmonary vessels	0.516	0.483
I27 Other pulmonary heart diseases	0.516	0.483
M48 Other spondylopathies	0.516	0.484
I10 Essential (primary) hypertension	0.515	0.485
C64 Malignant neoplasm of kidney, except renal pelvis	0.513	0.487
I51.9 Heart disease, unspecified	0.512	0.488
I51.8 Other ill-defined heart diseases	0.512	0.488
I51.6 Cardiovascular disease, unspecified	0.512	0.488
I51.5 Myocardial degeneration	0.512	0.488
I51.4 Myocarditis, unspecified	0.512	0.488
I51.3 Intracardiac thrombosis, not elsewhere classified	0.512	0.488
I51.2 Rupture of papillary muscle, not elsewhere classified	0.512	0.488
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.512	0.488
I51.0 Cardiac septal defect, acquired	0.512	0.488
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.512	0.488
I34.8 Other nonrheumatic mitral valve disorders	0.512	0.488
I34.2 Nonrheumatic mitral (valve) stenosis	0.512	0.488
I34.1 Mitral (valve) prolapse	0.512	0.488
N50.1 Vascular disorders of male genital organs	0.512	0.488
E03.9 Hypothyroidism, unspecified	0.511	0.489
S01 Open wound of head	0.510	0.490
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.509	0.490
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.509	0.490
T39.4 Antirheumatics, not elsewhere classified	0.509	0.490
T39.2 Pyrazolone derivatives	0.509	0.490
T39.0 Salicylates	0.509	0.490
M14 Arthropathies in other diseases classified elsewhere	0.509	0.491
M12 Other specific arthropathies	0.509	0.491
M11 Other crystal arthropathies	0.509	0.491
M10 Gout	0.509	0.491
M09 Juvenile arthritis in diseases classified elsewhere	0.509	0.491
M08 Juvenile arthritis	0.509	0.491
M07 Psoriatic and enteropathic arthropathies	0.509	0.491
M05 Seropositive rheumatoid arthritis	0.509	0.491
O68 Labour and delivery complicated by foetal stress [distress]	0.509	0.491
N20 Calculus of kidney and ureter	0.509	0.491
Z96.9 Presence of functional implant, unspecified	0.508	0.492
Z96.8 Presence of other specified functional implants	0.508	0.492
Z96.7 Presence of other bone and tendon implants	0.508	0.492
Z96.5 Presence of tooth-root and mandibular implants	0.508	0.492
Z96.4 Presence of endocrine implants	0.508	0.492
Z96.3 Presence of artificial larynx	0.508	0.492
Z96.2 Presence of otological and audiological implants	0.508	0.492
Z96.0 Presence of urogenital implants	0.508	0.492
I20.8 Other forms of angina pectoris	0.508	0.492
I20.1 Angina pectoris with documented spasm	0.508	0.492
C44.9 Malignant neoplasm of skin, unspecified	0.507	0.493
C44.8 Overlapping lesion of skin	0.507	0.493
C44.7 Skin of lower limb, including hip	0.507	0.493
C44.4 Skin of scalp and neck	0.507	0.493
C44.2 Skin of ear and external auricular canal	0.507	0.493
C44.1 Skin of eyelid, including canthus	0.507	0.493
C44.0 Skin of lip	0.507	0.493
I63 Cerebral infarction	0.507	0.493
E07 Other disorders of thyroid	0.506	0.493
E06 Thyroiditis	0.506	0.493
E04 Other non-toxic goitre	0.506	0.493
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.506	0.493
E00 Congenital iodine-deficiency syndrome	0.506	0.493
E02 Subclinical iodine-deficiency hypothyroidism	0.506	0.493
P90-P96 Other disorders originating in the perinatal period	0.506	0.494
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.506	0.494
P75-P78 Digestive system disorders of fetus and newborn	0.506	0.494
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.506	0.494
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.506	0.494
P35-P39 Infections specific to the perinatal period	0.506	0.494
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.506	0.494
P10-P15 Birth trauma	0.506	0.494
P05-P08 Disorders related to length of gestation and fetal growth	0.506	0.494
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.506	0.494
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.506	0.494
Q80-Q89 Other congenital malformations	0.506	0.494
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.506	0.494
Q60-Q64 Congenital malformations of the urinary system	0.506	0.494
Q50-Q56 Congenital malformations of genital organs	0.506	0.494
Q38-Q45 Other congenital malformations of the digestive system	0.506	0.494
Q35-Q37 Cleft lip and cleft palate	0.506	0.494
Q30-Q34 Congenital malformations of the respiratory system	0.506	0.494
Q20-Q28 Congenital malformations of the circulatory system	0.506	0.494
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.506	0.494
Q00-Q07 Congenital malformations of the nervous system	0.506	0.494
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.506	0.494

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations