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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1948390
log Bayes Factor = 10.3593
Chromosome 3   position 161,624,890  (GRCh37) Explore rs1948390 on Ensembl!
Variant rs1948390 is part of Cluster X0264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.999 0.001 0.000
F17.1 Harmful use
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.995 0.005 0.000
S00-S09 Injuries to the head
0.993 0.007 0.000
E10.9 Without complications
0.992 0.008 0.000
E11.3 With ophthalmic complications
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
S01 Open wound of head
0.987 0.013 0.000
M06 Other rheumatoid arthritis
0.985 0.015 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
M06.9 Rheumatoid arthritis, unspecified
0.971 0.029 0.000
E00-E07 Disorders of thyroid gland
0.946 0.054 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.945 0.055 0.000
E20-E35 Disorders of other endocrine glands
0.943 0.057 0.000
Chapter XX External causes of morbidity and mortality
0.929 0.071 0.000
H53-H54 Visual disturbances and blindness
0.925 0.075 0.000
S06 Intracranial injury
0.918 0.082 0.000
S01.0 Open wound of scalp
0.917 0.083 0.000
E04 Other non-toxic goitre
0.907 0.093 0.000
H30-H36 Disorders of choroid and retina
0.905 0.095 0.000
M86-M90 Other osteopathies
0.900 0.100 0.000
E11.2 With renal complications
0.897 0.103 0.000
S90-S99 Injuries to the ankle and foot
0.896 0.104 0.000
S10-S19 Injuries to the neck
0.895 0.105 0.000
F17.2 Dependence syndrome
0.894 0.106 0.000
S01.8 Open wound of other parts of head
0.884 0.116 0.000
E10.5 With peripheral circulatory complications
0.883 0.117 0.000
H36 Retinal disorders in diseases classified elsewhere
0.881 0.119 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.879 0.121 0.000
H54 Blindness and low vision
0.877 0.123 0.000
E10.2 With renal complications
0.870 0.130 0.000
S70-S79 Injuries to the hip and thigh
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.866 0.134 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.865 0.135 0.000
H36.0 Diabetic retinopathy
0.864 0.136 0.000
M06.4 Inflammatory polyarthropathy
0.862 0.138 0.000
E27 Other disorders of adrenal gland
0.859 0.141 0.000
M07 Psoriatic and enteropathic arthropathies
0.858 0.142 0.000
F30-F39 Mood [affective] disorders
0.855 0.145 0.000
S50-S59 Injuries to the elbow and forearm
0.853 0.147 0.000
H18 Other disorders of cornea
0.852 0.148 0.000
E04.2 Non-toxic multinodular goitre
0.852 0.148 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.850 0.150 0.000
S01.1 Open wound of eyelid and periocular area
0.849 0.151 0.000
Y95 Nosocomial condition
0.847 0.153 0.000
S60-S69 Injuries to the wrist and hand
0.846 0.154 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.846 0.154 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.842 0.158 0.000
H54.9 Unspecified visual impairment (binocular)
0.840 0.160 0.000
E40-E46 Malnutrition
0.838 0.162 0.000
S01.9 Open wound of head, part unspecified
0.833 0.167 0.000
E22 Hyperfunction of pituitary gland
0.831 0.169 0.000
M06.0 Seronegative rheumatoid arthritis
0.830 0.170 0.000
H20 Iridocyclitis
0.828 0.172 0.000
M05 Seropositive rheumatoid arthritis
0.825 0.175 0.000
E50-E64 Other nutritional deficiencies
0.823 0.177 0.000
S01.5 Open wound of lip and oral cavity
0.822 0.178 0.000
S05 Injury of eye and orbit
0.821 0.179 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.817 0.183 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.817 0.183 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.811 0.189 0.000
M10 Gout
0.808 0.192 0.000
Chapter IX Diseases of the circulatory system
0.807 0.193 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.805 0.195 0.000
S51 Open wound of forearm
0.804 0.196 0.000
Chapter XXII Codes for special purposes
0.804 0.196 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.803 0.197 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.797 0.203 0.000
W20-W49 Exposure to inanimate mechanical forces
0.796 0.204 0.000
E11.5 With peripheral circulatory complications
0.796 0.204 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.794 0.206 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
I34 Nonrheumatic mitral valve disorders
0.789 0.211 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.788 0.212 0.000
I30-I52 Other forms of heart disease
0.788 0.212 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.787 0.213 0.000
I34.0 Mitral (valve) insufficiency
0.787 0.213 0.000
E11.1 With ketoacidosis
0.785 0.215 0.000
M89 Other disorders of bone
0.785 0.215 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.784 0.216 0.000
M45-M49 Spondylopathies
0.784 0.216 0.000
M86 Osteomyelitis
0.783 0.217 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.781 0.219 0.000
E10.1 With ketoacidosis
0.779 0.221 0.000
F31 Bipolar affective disorder
0.772 0.228 0.000
S19 Other and unspecified injuries of neck
0.770 0.230 0.000
E11.4 With neurological complications
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.767 0.233 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.765 0.235 0.000
L40-L45 Papulosquamous disorders
0.765 0.235 0.000
S92 Fracture of foot, except ankle
0.764 0.236 0.000
M07.3 Other psoriatic arthropathies
0.764 0.236 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.760 0.240 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.760 0.240 0.000
M85 Other disorders of bone density and structure
0.759 0.241 0.000
S06.2 Diffuse brain injury
0.759 0.241 0.000
E04.1 Non-toxic single thyroid nodule
0.758 0.242 0.000
E11.8 With unspecified complications
0.754 0.245 0.000
H34 Retinal vascular occlusions
0.754 0.246 0.000
T00-T07 Injuries involving multiple body regions
0.754 0.246 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.751 0.249 0.000
S06.4 Epidural haemorrhage
0.749 0.251 0.000
Chapter I Certain infectious and parasitic diseases
0.749 0.251 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.748 0.252 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.748 0.252 0.000
H55-H59 Other disorders of eye and adnexa
0.747 0.253 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.746 0.254 0.000
I60-I69 Cerebrovascular diseases
0.745 0.255 0.000
L03 Cellulitis
0.744 0.256 0.000
E11.0 With coma
0.741 0.258 0.000
S06.0 Concussion
0.741 0.259 0.000
S01.4 Open wound of cheek and temporomandibular area
0.740 0.259 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.740 0.260 0.000
E13 Other specified diabetes mellitus
0.740 0.260 0.000
S01.7 Multiple open wounds of head
0.737 0.263 0.000
M14 Arthropathies in other diseases classified elsewhere
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.735 0.265 0.000
E20 Hypoparathyroidism
0.735 0.265 0.000
M06.3 Rheumatoid nodule
0.732 0.268 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.732 0.268 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.732 0.268 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.730 0.270 0.000
W00-W19 Falls
0.729 0.271 0.000
H21 Other disorders of iris and ciliary body
0.728 0.272 0.000
L50-L54 Urticaria and erythema
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.725 0.275 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.725 0.275 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.724 0.275 0.000
S32 Fracture of lumbar spine and pelvis
0.723 0.277 0.000
S91 Open wound of ankle and foot
0.723 0.277 0.000
E46 Unspecified protein-energy malnutrition
0.722 0.278 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.722 0.278 0.000
M84 Disorders of continuity of bone
0.721 0.279 0.000
E11.6 With other specified complications
0.721 0.279 0.000
E34 Other endocrine disorders
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.283 0.000
F17.9 Unspecified mental and behavioural disorder
0.716 0.284 0.000
F17.8 Other mental and behavioural disorders
0.716 0.284 0.000
F17.7 Residual and late-onset psychotic disorder
0.716 0.284 0.000
F17.6 Amnesic syndrome
0.716 0.284 0.000
F17.5 Psychotic disorder
0.716 0.284 0.000
F17.4 Withdrawal state with delirium
0.716 0.284 0.000
F17.3 Withdrawal state
0.716 0.284 0.000
F17.0 Acute intoxication
0.716 0.284 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
E10.8 With unspecified complications
0.716 0.284 0.000
E10.7 With multiple complications
0.716 0.284 0.000
E10.6 With other specified complications
0.716 0.284 0.000
E10.0 With coma
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
L40 Psoriasis
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E16.1 Other hypoglycaemia
0.714 0.286 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.714 0.286 0.000
S01.3 Open wound of ear
0.714 0.286 0.000
E27.2 Addisonian crisis
0.713 0.287 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.713 0.287 0.000
F33 Recurrent depressive disorder
0.712 0.288 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.712 0.288 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
H16 Keratitis
0.711 0.289 0.000
H20.9 Iridocyclitis, unspecified
0.711 0.289 0.000
H54.0 Blindness, both eyes
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.710 0.290 0.000
M12 Other specific arthropathies
0.709 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.290 0.000
M08 Juvenile arthritis
0.709 0.290 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.709 0.291 0.000
T18 Foreign body in alimentary tract
0.709 0.291 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.706 0.294 0.000
M06.2 Rheumatoid bursitis
0.706 0.294 0.000
M06.1 Adult-onset Still's disease
0.706 0.294 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.706 0.294 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
H18.5 Hereditary corneal dystrophies
0.703 0.297 0.000
H53 Visual disturbances
0.702 0.298 0.000
H18.2 Other corneal oedema
0.702 0.298 0.000
S20-S29 Injuries to the thorax
0.700 0.300 0.000
S51.0 Open wound of elbow
0.700 0.300 0.000
S06.8 Other intracranial injuries
0.699 0.301 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.696 0.304 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.696 0.304 0.000
E28 Ovarian dysfunction
0.694 0.305 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.695 0.305 0.000
S05.8 Other injuries of eye and orbit
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.307 0.000
E06 Thyroiditis
0.690 0.310 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
M85.8 Other specified disorders of bone density and structure
0.687 0.313 0.000
S90 Superficial injury of ankle and foot
0.687 0.313 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.687 0.313 0.000
H18.4 Corneal degeneration
0.686 0.314 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.685 0.314 0.000
E61 Deficiency of other nutrient elements
0.685 0.315 0.000
S10 Superficial injury of neck
0.685 0.315 0.000
S79 Other and unspecified injuries of hip and thigh
0.684 0.316 0.000
M45 Ankylosing spondylitis
0.684 0.316 0.000
L20-L30 Dermatitis and eczema
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.683 0.317 0.000
M11 Other crystal arthropathies
0.683 0.317 0.000
H10-H13 Disorders of conjunctiva
0.683 0.317 0.000
E04.9 Non-toxic goitre, unspecified
0.680 0.319 0.000
F12.2 Dependence syndrome
0.680 0.320 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.678 0.321 0.000
E00 Congenital iodine-deficiency syndrome
0.678 0.321 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.678 0.321 0.000
M10.9 Gout, unspecified
0.678 0.322 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.678 0.322 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.678 0.322 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.678 0.322 0.000
H15 Disorders of sclera
0.678 0.322 0.000
S72 Fracture of femur
0.678 0.322 0.000
E24 Cushing's syndrome
0.677 0.323 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.677 0.323 0.000
W19 Unspecified fall
0.677 0.323 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.676 0.324 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.676 0.324 0.000
E32 Diseases of thymus
0.676 0.324 0.000
E31 Polyglandular dysfunction
0.676 0.324 0.000
E30 Disorders of puberty, not elsewhere classified
0.676 0.324 0.000
E26 Hyperaldosteronism
0.676 0.324 0.000
E25 Adrenogenital disorders
0.676 0.324 0.000
E07 Other disorders of thyroid
0.675 0.324 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.675 0.325 0.000
S70 Superficial injury of hip and thigh
0.673 0.327 0.000
B15-B19 Viral hepatitis
0.672 0.328 0.000
E27.8 Other specified disorders of adrenal gland
0.672 0.328 0.000
S51.8 Open wound of other parts of forearm
0.672 0.328 0.000
S06.5 Traumatic subdural haemorrhage
0.671 0.328 0.000
E27.9 Disorder of adrenal gland, unspecified
0.671 0.329 0.000
M89.9 Disorder of bone, unspecified
0.671 0.329 0.000
F99-F99 Unspecified mental disorder
0.671 0.329 0.000
S51.9 Open wound of forearm, part unspecified
0.671 0.329 0.000
X60-X84 Intentional self-harm
0.669 0.331 0.000
L03.1 Cellulitis of other parts of limb
0.669 0.331 0.000
S64 Injury of nerves at wrist and hand level
0.669 0.331 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.668 0.331 0.000
E65-E68 Obesity and other hyperalimentation
0.668 0.331 0.000
T87 Complications peculiar to reattachment and amputation
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.668 0.332 0.000
S02 Fracture of skull and facial bones
0.667 0.333 0.000
M86.9 Osteomyelitis, unspecified
0.667 0.333 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.666 0.334 0.000
Y10-Y34 Event of undetermined intent
0.666 0.334 0.000
Y00-Y09 Assault
0.666 0.334 0.000
X85-X99 Assault
0.666 0.334 0.000
X30-X39 Exposure to forces of nature
0.666 0.334 0.000
X00-X09 Exposure to smoke, fire and flames
0.666 0.334 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.666 0.334 0.000
W75-W84 Other accidental threats to breathing
0.666 0.334 0.000
W65-W74 Accidental drowning and submersion
0.666 0.334 0.000
W50-W64 Exposure to animate mechanical forces
0.666 0.334 0.000
V98-V99 Other and unspecified transport accidents
0.666 0.334 0.000
V95-V97 Air and space transport accidents
0.666 0.334 0.000
V90-V94 Water transport accidents
0.666 0.334 0.000
V70-V79 Bus occupant injured in transport accident
0.666 0.334 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.666 0.334 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.666 0.334 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.666 0.334 0.000
V01-V09 Pedestrian injured in transport accident
0.666 0.334 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.666 0.334 0.000
S62 Fracture at wrist and hand level
0.666 0.334 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.664 0.336 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.664 0.336 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.663 0.337 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.663 0.337 0.000
I45 Other conduction disorders
0.663 0.337 0.000
E55 Vitamin D deficiency
0.662 0.337 0.000
H17 Corneal scars and opacities
0.662 0.338 0.000
S99 Other and unspecified injuries of ankle and foot
0.661 0.338 0.000
S32.5 Fracture of pubis
0.661 0.339 0.000
W44 Foreign body entering into or through eye or natural orifice
0.661 0.339 0.000
E29 Testicular dysfunction
0.661 0.339 0.000
I34.1 Mitral (valve) prolapse
0.659 0.341 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.659 0.341 0.000
H20.8 Other iridocyclitis
0.659 0.341 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.659 0.341 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.658 0.341 0.000
E10.4 With neurological complications
0.658 0.341 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.658 0.342 0.000
S06.9 Intracranial injury, unspecified
0.658 0.342 0.000
S06.7 Intracranial injury with prolonged coma
0.658 0.342 0.000
S06.1 Traumatic cerebral oedema
0.658 0.342 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.658 0.342 0.000
S71 Open wound of hip and thigh
0.658 0.342 0.000
Y65 Other misadventures during surgical and medical care
0.656 0.344 0.000
F30 Manic episode
0.655 0.345 0.000
I42 Cardiomyopathy
0.655 0.345 0.000
M82 Osteoporosis in diseases classified elsewhere
0.654 0.346 0.000
F60-F69 Disorders of adult personality and behaviour
0.654 0.346 0.000
T17 Foreign body in respiratory tract
0.653 0.347 0.000
F43 Reaction to severe stress, and adjustment disorders
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.651 0.349 0.000
S12 Fracture of neck
0.651 0.349 0.000
H31 Other disorders of choroid
0.651 0.349 0.000
E04.8 Other specified non-toxic goitre
0.650 0.350 0.000
E04.0 Non-toxic diffuse goitre
0.650 0.350 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.649 0.351 0.000
H30 Chorioretinal inflammation
0.649 0.351 0.000
O36 Maternal care for other known or suspected foetal problems
0.649 0.351 0.000
F01 Vascular dementia
0.647 0.353 0.000
M90 Osteopathies in diseases classified elsewhere
0.647 0.353 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.645 0.354 0.000
I65.2 Occlusion and stenosis of carotid artery
0.645 0.355 0.000
S56 Injury of muscle and tendon at forearm level
0.645 0.355 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.645 0.355 0.000
E10.3 With ophthalmic complications
0.643 0.357 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.643 0.357 0.000
S98 Traumatic amputation of ankle and foot
0.643 0.357 0.000
S97 Crushing injury of ankle and foot
0.643 0.357 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.643 0.357 0.000
S95 Injury of blood vessels at ankle and foot level
0.643 0.357 0.000
S94 Injury of nerves at ankle and foot level
0.643 0.357 0.000
S19.9 Unspecified injury of neck
0.642 0.358 0.000
S17 Crushing injury of neck
0.642 0.358 0.000
S15 Injury of blood vessels at neck level
0.642 0.358 0.000
S14 Injury of nerves and spinal cord at neck level
0.642 0.358 0.000
S11 Open wound of neck
0.642 0.358 0.000
S18 Traumatic amputation at neck level
0.642 0.358 0.000
S16 Injury of muscle and tendon at neck level
0.642 0.358 0.000
F31.9 Bipolar affective disorder, unspecified
0.641 0.359 0.000
M88 Paget's disease of bone [osteitis deformans]
0.639 0.361 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.638 0.362 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.636 0.364 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.635 0.365 0.000
O47 False labour
0.634 0.366 0.000
H18.6 Keratoconus
0.633 0.367 0.000
T51 Toxic effect of alcohol
0.633 0.367 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.632 0.368 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.632 0.368 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.631 0.369 0.000
Y98 Lifestyle-related condition
0.631 0.369 0.000
Y97 Environmental-pollution-related condition
0.631 0.369 0.000
Y96 Work-related condition
0.631 0.369 0.000
X20-X29 Contact with venomous animals and plants
0.630 0.370 0.000
M83 Adult osteomalacia
0.630 0.370 0.000
H43-H45 Disorders of vitreous body and globe
0.630 0.370 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.630 0.370 0.000
H54.6 Unqualified visual loss, one eye
0.629 0.371 0.000
H54.5 Low vision, one eye
0.629 0.371 0.000
H54.3 Unqualified visual loss, both eyes
0.629 0.371 0.000
H54.2 Low vision, both eyes
0.629 0.371 0.000
H54.1 Blindness, one eye, low vision, other eye
0.629 0.371 0.000
L40.5 Arthropathic psoriasis
0.629 0.371 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.628 0.372 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.628 0.372 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.627 0.373 0.000
M80 Osteoporosis with pathological fracture
0.627 0.373 0.000
Q50-Q56 Congenital malformations of genital organs
0.627 0.373 0.000
M89.5 Osteolysis
0.627 0.373 0.000
S68 Traumatic amputation of wrist and hand
0.626 0.374 0.000
H02 Other disorders of eyelid
0.626 0.374 0.000
L03.3 Cellulitis of trunk
0.625 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.625 0.375 0.000
E27.1 Primary adrenocortical insufficiency
0.625 0.375 0.000
I51 Complications and ill-defined descriptions of heart disease
0.624 0.376 0.000
M86.6 Other chronic osteomyelitis
0.624 0.376 0.000
H02.8 Other specified disorders of eyelid
0.623 0.377 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.622 0.377 0.000
H34.2 Other retinal artery occlusions
0.622 0.378 0.000
S78 Traumatic amputation of hip and thigh
0.621 0.378 0.000
S77 Crushing injury of hip and thigh
0.621 0.378 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.621 0.378 0.000
S75 Injury of blood vessels at hip and thigh level
0.621 0.378 0.000
S74 Injury of nerves at hip and thigh level
0.621 0.378 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.621 0.378 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.622 0.378 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.621 0.378 0.000
Q35-Q37 Cleft lip and cleft palate
0.621 0.378 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.621 0.378 0.000
L10-L14 Bullous disorders
0.621 0.379 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.620 0.380 0.000
I50 Heart failure
0.619 0.381 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.618 0.382 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.618 0.382 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.618 0.382 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.618 0.382 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.618 0.382 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.618 0.382 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.618 0.382 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.618 0.382 0.000
S19.8 Other specified injuries of neck
0.618 0.382 0.000
Q80-Q89 Other congenital malformations
0.618 0.382 0.000
S32.50 Fracture of pubis (closed)
0.617 0.383 0.000
B25-B34 Other viral diseases
0.617 0.383 0.000
E27.5 Adrenomedullary hyperfunction
0.616 0.384 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.616 0.384 0.000
E27.0 Other adrenocortical overactivity
0.616 0.384 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.616 0.384 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.615 0.385 0.000
M07.6 Other enteropathic arthropathies
0.615 0.385 0.000
M07.5 Arthropathy in ulcerative colitis
0.615 0.385 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.615 0.385 0.000
M07.2 Psoriatic spondylitis
0.615 0.385 0.000
M07.1 Arthritis mutilans
0.615 0.385 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.615 0.385 0.000
L03.2 Cellulitis of face
0.615 0.385 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.614 0.386 0.000
S06.00 Concussion (without open intracranial wound)
0.614 0.386 0.000
S01.2 Open wound of nose
0.613 0.386 0.000
F38 Other mood [affective] disorders
0.613 0.387 0.000
F34 Persistent mood [affective] disorders
0.613 0.387 0.000
F39 Unspecified mood [affective] disorder
0.613 0.387 0.000
T85.2 Mechanical complication of intraocular lens
0.613 0.387 0.000
F42 Obsessive-compulsive disorder
0.613 0.387 0.000
V80-V89 Other land transport accidents
0.612 0.388 0.000
B99-B99 Other infectious diseases
0.612 0.388 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.612 0.388 0.000
S59 Other and unspecified injuries of forearm
0.612 0.388 0.000
S58 Traumatic amputation of forearm
0.612 0.388 0.000
S57 Crushing injury of forearm
0.612 0.388 0.000
S55 Injury of blood vessels at forearm level
0.612 0.388 0.000
S54 Injury of nerves at forearm level
0.612 0.388 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.612 0.388 0.000
H18.9 Disorder of cornea, unspecified
0.611 0.389 0.000
H18.7 Other corneal deformities
0.611 0.389 0.000
H18.3 Changes in corneal membranes
0.611 0.389 0.000
H18.1 Bullous keratopathy
0.611 0.389 0.000
H18.0 Corneal pigmentations and deposits
0.611 0.389 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.610 0.389 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.610 0.390 0.000
S09 Other and unspecified injuries of head
0.610 0.390 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.610 0.390 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.610 0.390 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.610 0.390 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.610 0.390 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.610 0.390 0.000
T36 Poisoning by systemic antibiotics
0.610 0.390 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.610 0.390 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.608 0.392 0.000
W25 Contact with sharp glass
0.607 0.393 0.000
S65 Injury of blood vessels at wrist and hand level
0.607 0.393 0.000
T19 Foreign body in genito-urinary tract
0.606 0.393 0.000
T15 Foreign body on external eye
0.606 0.393 0.000
T16 Foreign body in ear
0.606 0.393 0.000
S67 Crushing injury of wrist and hand
0.606 0.394 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.606 0.394 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.606 0.394 0.000
T21 Burn and corrosion of trunk
0.605 0.395 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.605 0.395 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.603 0.397 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.603 0.397 0.000
B18 Chronic viral hepatitis
0.603 0.397 0.000
H55 Nystagmus and other irregular eye movements
0.603 0.397 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.603 0.397 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.602 0.397 0.000
S60 Superficial injury of wrist and hand
0.602 0.398 0.000
O00-O08 Pregnancy with abortive outcome
0.602 0.398 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.601 0.399 0.000
E45 Retarded development following protein-energy malnutrition
0.601 0.399 0.000
E43 Unspecified severe protein-energy malnutrition
0.601 0.399 0.000
E42 Marasmic kwashiorkor
0.601 0.399 0.000
E41 Nutritional marasmus
0.601 0.399 0.000
E40 Kwashiorkor
0.601 0.399 0.000
S92.0 Fracture of calcaneus
0.600 0.400 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.600 0.400 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.599 0.401 0.000
S92.5 Fracture of other toe
0.599 0.401 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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